fortified food

Summary

Summary: Any food that has been supplemented with essential nutrients either in quantities that are greater than those present normally, or which are not present in the fortified food. The supplementation of cereals with iron and vitamins is an example of fortified food. Fortified food includes also enriched food to which various nutrients have been added to compensate for those essential nutrients removed by refinement or processing. (From Segen, Dictionary of Modern Medicine, 1992)

Top Publications

  1. ncbi A safe strategy for addition of vitamins and minerals to foods
    S E Rasmussen
    Danish Institute for Food and Veterinary Research, 19 Mørkhøj Bygade, 2860, Søborg, Denmark
    Eur J Nutr 45:123-35. 2006
  2. ncbi Conclusions of a WHO Technical Consultation on folate and vitamin B12 deficiencies
    Bruno de Benoist
    Department of Nutrition for Health and Development, World Health Organization, 20 Avenue Appia, CH 1211, Geneva 27, Switzerland
    Food Nutr Bull 29:S238-44. 2008
  3. ncbi Vitamins and minerals: a model for safe addition to foods
    Albert Flynn
    University College Cork, Department of Food and Nutritional Sciences, Cork, Ireland
    Eur J Nutr 42:118-30. 2003
  4. ncbi Iron-biofortified rice improves the iron stores of nonanemic Filipino women
    Jere D Haas
    Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
    J Nutr 135:2823-30. 2005
  5. ncbi Randomized, double-blind, placebo-controlled trial of an iron-fortified food product in female soldiers during military training: relations between iron status, serum hepcidin, and inflammation
    J Philip Karl
    US Army Research Institute of Environmental Medicine, Natick, MA, USA
    Am J Clin Nutr 92:93-100. 2010
  6. pmc Micronutrient sprinkles to control childhood anaemia
    Stanley H Zlotkin
    Division of GI Nutrition at the Hospital for Sick Children, Toronto, Ontario, Canada
    PLoS Med 2:e1. 2005
  7. ncbi Reduction of birth prevalence rates of neural tube defects after folic acid fortification in Chile
    Jorge S Lopez-Camelo
    Estudo Colaborativo Latino Americano de Malformações Congênitas, ECLAMC at IMBICE, Instituto Multidisciplinario de Biologia Celular, La Plata, Argentina
    Am J Med Genet A 135:120-5. 2005
  8. ncbi Vitamin intakes from supplements and fortified food in German children and adolescents: results from the DONALD study
    Wolfgang Sichert-Hellert
    Research Institute of Child Nutrition FKE, Dortmund and Rheinische Friedrich Wilhelms Universität, Bonn, Germany
    J Nutr 136:1329-33. 2006
  9. ncbi Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial
    D L O'Connor
    Ross Products Division, Abbott Labs, Columbus, Ohio, USA
    Pediatrics 108:359-71. 2001
  10. ncbi The effect of folate fortification of cereal-grain products on blood folate status, dietary folate intake, and dietary folate sources among adult non-supplement users in the United States
    Marion Dietrich
    School of Public Health, University of California Berkeley, Berkeley, CA, USA
    J Am Coll Nutr 24:266-74. 2005

Research Grants

Detail Information

Publications194 found, 100 shown here

  1. ncbi A safe strategy for addition of vitamins and minerals to foods
    S E Rasmussen
    Danish Institute for Food and Veterinary Research, 19 Mørkhøj Bygade, 2860, Søborg, Denmark
    Eur J Nutr 45:123-35. 2006
    ..We suggest that the MA should be expressed in weight units per energy unit in order to distribute it equally between potentially fortifiable food groups according to their usual contribution to total energy intakes...
  2. ncbi Conclusions of a WHO Technical Consultation on folate and vitamin B12 deficiencies
    Bruno de Benoist
    Department of Nutrition for Health and Development, World Health Organization, 20 Avenue Appia, CH 1211, Geneva 27, Switzerland
    Food Nutr Bull 29:S238-44. 2008
  3. ncbi Vitamins and minerals: a model for safe addition to foods
    Albert Flynn
    University College Cork, Department of Food and Nutritional Sciences, Cork, Ireland
    Eur J Nutr 42:118-30. 2003
    ..However, concerns need to be addressed regarding the potential for unacceptably high intakes, particularly for those people consuming very large amounts of food...
  4. ncbi Iron-biofortified rice improves the iron stores of nonanemic Filipino women
    Jere D Haas
    Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
    J Nutr 135:2823-30. 2005
    ..Consumption of biofortified rice, without any other changes in diet, is efficacious in improving iron stores of women with iron-poor diets in the developing world...
  5. ncbi Randomized, double-blind, placebo-controlled trial of an iron-fortified food product in female soldiers during military training: relations between iron status, serum hepcidin, and inflammation
    J Philip Karl
    US Army Research Institute of Environmental Medicine, Natick, MA, USA
    Am J Clin Nutr 92:93-100. 2010
    ..Iron status degrades in female soldiers during military training. Inflammation-mediated up-regulation of hepcidin, a key mediator of iron homeostasis, may be a contributing factor...
  6. pmc Micronutrient sprinkles to control childhood anaemia
    Stanley H Zlotkin
    Division of GI Nutrition at the Hospital for Sick Children, Toronto, Ontario, Canada
    PLoS Med 2:e1. 2005
  7. ncbi Reduction of birth prevalence rates of neural tube defects after folic acid fortification in Chile
    Jorge S Lopez-Camelo
    Estudo Colaborativo Latino Americano de Malformações Congênitas, ECLAMC at IMBICE, Instituto Multidisciplinario de Biologia Celular, La Plata, Argentina
    Am J Med Genet A 135:120-5. 2005
    ..Within the methodological constraints of this study we conclude that the birth prevalence rates for both spina bifida and anencephaly decreased as a result of folic acid fortification, without interference of decreasing secular trends...
  8. ncbi Vitamin intakes from supplements and fortified food in German children and adolescents: results from the DONALD study
    Wolfgang Sichert-Hellert
    Research Institute of Child Nutrition FKE, Dortmund and Rheinische Friedrich Wilhelms Universität, Bonn, Germany
    J Nutr 136:1329-33. 2006
    ..K, thiamin, riboflavin, vitamin B-6, vitamin B-12, niacin, biotin, and vitamin C), intake from usual and fortified food already reached or exceeded 80% of the recommended dietary allowances in all age groups...
  9. ncbi Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial
    D L O'Connor
    Ross Products Division, Abbott Labs, Columbus, Ohio, USA
    Pediatrics 108:359-71. 2001
    ....
  10. ncbi The effect of folate fortification of cereal-grain products on blood folate status, dietary folate intake, and dietary folate sources among adult non-supplement users in the United States
    Marion Dietrich
    School of Public Health, University of California Berkeley, Berkeley, CA, USA
    J Am Coll Nutr 24:266-74. 2005
    ..S. population following folic acid fortification of enriched cereal-grain products and to explore accompanying changes in food sources and dietary total folate intake...
  11. ncbi Iron fortification and iron supplementation are cost-effective interventions to reduce iron deficiency in four subregions of the world
    Rob Baltussen
    WHO CHOICE, Institute for Medical Technology Assessment, Erasmus Medical Center, Rotterdam, The Netherlands
    J Nutr 134:2678-84. 2004
    ..The results should be interpreted with caution, because evidence of intervention effectiveness predominantly relates to small-scale efficacy trials, which may not reflect the actual effect under expected conditions...
  12. ncbi How to ensure adequate iron absorption from iron-fortified food
    Richard Hurrell
    Laboratory of Human Nutrition, Institute of Food Science EHZ, Ruschlikon, Switzerland
    Nutr Rev 60:S7-15; discussion S43. 2002
  13. ncbi The use of high-selenium yeast to raise selenium status: how does it measure up?
    Margaret P Rayman
    Centre for Nutrition and Food Safety, School of Biomedical and Molecular Sciences, University of Surrey, UK
    Br J Nutr 92:557-73. 2004
    ..It is concluded that Se-yeast from reputable manufacturers is adequately characterised, of reproducible quality, and that there is no evidence of toxicity even at levels far above the EC tolerable upper intake level of 300 microg/d...
  14. ncbi Home-fortification with iron and zinc sprinkles or iron sprinkles alone successfully treats anemia in infants and young children
    Stanley Zlotkin
    Departments of Paediatrics and Nutritional Sciences, University of Toronto, Canada
    J Nutr 133:1075-80. 2003
    ....
  15. ncbi Impact of foods enriched with n-3 long-chain polyunsaturated fatty acids on erythrocyte n-3 levels and cardiovascular risk factors
    Karen J Murphy
    Nutritional Physiology Research Centre, Division of Health Sciences, University of South Australia and School of Molecular and Biomedical Science, University of Adelaide, Adelaide, SA
    Br J Nutr 97:749-57. 2007
    ..Sustainable increases in dietary intakes and erythrocyte levels of n-3 long-chain PUFA can be achieved through regular consumption of suitably enriched processed foods. Such increases may be associated with reduced CV risk...
  16. ncbi Ten-year trends in vitamin and mineral intake from fortified food in German children and adolescents
    W Sichert-Hellert
    Research Institute of Child Nutrition FKE, Dortmund, Germany
    Eur J Clin Nutr 54:81-6. 2000
    ..patterns, and energy and nutrient intakes (protein, fat, carbohydrates, added sugars, vitamins A, E, C, B1, B2 and B6, niacin, folate, calcium and iron) from fortified food in children and adolescents between 1987 and 1996 in Germany.
  17. pmc Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada
    Raluca Ionescu-Ittu
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada
    BMJ 338:b1673. 2009
    ..To investigate whether the 1998 government policy for mandatory fortification of flour and pasta products with folate was followed by a reduction in the prevalence of severe congenital heart defects...
  18. ncbi Effect of a fortified maize-meal porridge on anemia, micronutrient status, and motor development of infants
    Mieke Faber
    Nutritional Intervention Research Unit, Medical Research Council, Tygerberg, South Africa
    Am J Clin Nutr 82:1032-9. 2005
    ..A low-cost, finely milled, maize-meal porridge was fortified with beta-carotene, iron, and zinc (100% of recommended dietary allowance), as well as ascorbic acid, copper, selenium, riboflavin, vitamin B-6, vitamin B-12, and vitamin E...
  19. ncbi Folate intakes and awareness of folate to prevent neural tube defects: a survey of women living in Vancouver, Canada
    Melissa R French
    Osteoporosis Research Program, Sunnybrook and Women s College Health Sciences Centre, Toronto, ON, Canada
    J Am Diet Assoc 103:181-5. 2003
    ..To estimate folate intake and knowledge in women of childbearing age, in relation to risk of neural tube defects...
  20. ncbi The use of NaFeEDTA-fortified fish sauce is an effective tool for controlling iron deficiency in women of childbearing age in rural Vietnam
    Pham Van Thuy
    The National Institute of Nutrition, Hanoi, Vietnam
    J Nutr 135:2596-601. 2005
    ..7 to 8.5% in Group F with no significant changes in Group C. NaFeEDTA fortification of fish sauce is an effective method for reducing the prevalence of iron deficiency in women in Vietnam...
  21. ncbi One-third of pregnant and lactating women may not be meeting their folate requirements from diet alone based on mandated levels of folic acid fortification
    Kelly L Sherwood
    Department of Nutritional Sciences, University of Toronto, Toronto, Canada
    J Nutr 136:2820-6. 2006
    ....
  22. ncbi Growth and change in blood haemoglobin concentration among underweight Malawian infants receiving fortified spreads for 12 weeks: a preliminary trial
    Heli Kuusipalo
    Department of International Health, University of Tampere Medical School, Tampere, Finland
    J Pediatr Gastroenterol Nutr 43:525-32. 2006
    ..We examined acceptability, growth and change in blood haemoglobin (Hb) concentration among moderately underweight ambulatory infants given FS...
  23. ncbi Regular consumption of NaFeEDTA-fortified fish sauce improves iron status and reduces the prevalence of anemia in anemic Vietnamese women
    Pham Van Thuy
    National Institute of Nutrition, Hanoi, Vietnam
    Am J Clin Nutr 78:284-90. 2003
    ..Fish sauce is consumed daily by a large proportion of the Vietnamese population and could therefore be a potentially useful food vehicle for iron-fortification programs...
  24. pmc Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians
    John C Phuka
    College of Medicine, University of Malawi, PO Box 431, Mangochi, Malawi
    Arch Pediatr Adolesc Med 162:619-26. 2008
    ..To compare growth and incidence of malnutrition in infants receiving long-term dietary supplementation with ready-to-use fortified spread (FS) or micronutrient-fortified maize-soy flour (likuni phala [LP])...
  25. ncbi Traditional foods vs. manufactured baby foods
    Elaine L Ferguson
    Department of Human Nutrition, University of Otago, Dunedin, New Zealand
    Nestle Nutr Workshop Ser Pediatr Program 60:43-61; discussion 61-3. 2007
    ..In all environments, the promotion of breastfeeding, active feeding and high levels of hygiene is essential to ensure optimal nutritional status...
  26. ncbi Reduction in neural-tube defects after folic acid fortification in Canada
    Philippe De Wals
    Laval University, Quebec, Canada
    N Engl J Med 357:135-42. 2007
    ..We assessed changes in the prevalence of neural-tube defects in Canada before and after food fortification with folic acid was implemented...
  27. ncbi Effect of iron-, iodine-, and beta-carotene-fortified biscuits on the micronutrient status of primary school children: a randomized controlled trial
    M E Van Stuijvenberg
    National Research Programme for Nutritional Intervention, Medical Research Council, Parow, South Africa
    Am J Clin Nutr 69:497-503. 1999
    ..Deficiencies of iron, iodine, and vitamin A are prevalent worldwide and can affect the mental development and learning ability of schoolchildren...
  28. ncbi A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis
    Joel B Mason
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Cancer Epidemiol Biomarkers Prev 16:1325-9. 2007
    ..Further work is needed to definitively establish the nature of this relationship. In the meantime, deliberations about the institution or enhancement of fortification programs should be undertaken with these considerations in mind...
  29. ncbi Proposed nutrient composition for fortified complementary foods
    Chessa K Lutter
    Nutrition Unit, Pan American Health Organization, Washington DC 20037, USA
    J Nutr 133:3011S-20S. 2003
    ..To prevent micronutrient losses, it is recommended that the FPCF be precooked. The knowledge base to develop an FPCF is quite limited, and much additional research is needed before an optimal formulation can be recommended...
  30. ncbi Comparison of the effects of zinc delivered in a fortified food or a liquid supplement on the growth, morbidity, and plasma zinc concentrations of young Peruvian children
    Kenneth H Brown
    Department of Nutrition and Program in International and Community Nutrition, University of California, Davis, CA 95616, USA
    Am J Clin Nutr 85:538-47. 2007
    ..Zinc supplementation decreases morbidity from infections and increases growth of stunted children, but there is little information on functional responses to zinc delivered in fortified foods...
  31. ncbi Association of neural tube defects and folic acid food fortification in Canada
    Joel G Ray
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Lancet 360:2047-8. 2002
    ..58 per 1000 pregnancies thereafter (prevalence ratio 0.52, 95% CI 0.40-0.67, p<0.0001). At a population level, folic acid food fortification is associated with a pronounced reduction in open neural tube defects...
  32. ncbi Changes in time-trends of nutrient intake from fortified and non-fortified food in German children and adolescents--15 year results of the DONALD study. Dortmund Nutritional and Anthropometric Longitudinally Designed Study
    W Sichert-Hellert
    Forschungsinstitut für Kinderernährung Dortmund FKE, Germany
    Eur J Nutr 40:49-55. 2001
    Although fortified products have played an increasing role in food marketing since the 1980s in Germany, data as to the consumption of fortified food is sparse.
  33. ncbi Increased food intake after the addition of amylase-rich flour to supplementary food for malnourished children in rural communities of Bangladesh
    M Iqbal Hossain
    International Centre for Diarrhoeal Disease Research, Bangladesh, Centre for Health and Population Research, Mohakhali, Dhaka, Bangladesh
    Food Nutr Bull 26:323-9. 2005
    ..In Bangladesh, as in other developing countries, protein-energy malnutrition is mostprevalent among children during weaning. After weaning, children are often fed cereal-based diluted low-calorie porridge, resulting in growth-faltering...
  34. ncbi Effect of a multiple-micronutrient-fortified fruit powder beverage on the nutrition status, physical fitness, and cognitive performance of schoolchildren in the Philippines
    Florentino S Solon
    Nutrition Center of the Philippines, Western Bicutan, Taguig, Metro Manila
    Food Nutr Bull 24:S129-40. 2003
    ..The results from the clinical study showed that a multiple-micronutrient-fortified beverage could play an important role in preventing and controlling micronutrient deficiencies...
  35. ncbi Folic acid food fortification in Canada
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Nutr Rev 62:S35-9. 2004
    ..The current report outlines some of the changes to the health status of Canadians in relation to its folic acid food fortification initiative...
  36. ncbi Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids
    Eduardo Lopez-Huertas
    Institute of Food Research, Norwich, United Kingdom
    Am J Clin Nutr 83:310-6. 2006
    ..Adequate intakes of calcium are required for optimal bone health and protection against chronic disease. Dairy products are an excellent source of calcium...
  37. ncbi Survival of infants with neural tube defects in the presence of folic acid fortification
    Kirk A Bol
    Colorado Responds to Children With Special Needs, Colorado Department of Public Health and Environment, Denver, CO 80246, USA
    Pediatrics 117:803-13. 2006
    ....
  38. ncbi Breast milk intake is not reduced more by the introduction of energy dense complementary food than by typical infant porridge
    Lauren Galpin
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA
    J Nutr 137:1828-33. 2007
    ..69 for effect of type of food). The results suggest that complementary feeding of Malawian infants with FS has the same effect on their breast milk intake as complementary feeding with traditional CSB porridge...
  39. ncbi Biofortification of staple food crops
    Penelope Nestel
    HarvestPlus, International Food Policy Research Institute, Washington, DC, USA
    J Nutr 136:1064-7. 2006
    ..With the advent of good seed systems, the development of markets and products, and demand creation, this can be achieved...
  40. ncbi Folic acid - vitamin and panacea or genetic time bomb?
    Mark Lucock
    School of Applied Sciences, University of Newcastle, Brush Rd, Ourimbah, NSW 2258, Australia
    Nat Rev Genet 6:235-40. 2005
    ..Are we affecting our genetics - is this a case of human evolution in progress by altering our diet?..
  41. ncbi Spread fortified with vitamins and minerals induces catch-up growth and eradicates severe anemia in stunted refugee children aged 3-6 y
    Cristina Lopriore
    Department of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Am J Clin Nutr 80:973-81. 2004
    ..No generally accepted recommendations for micronutrient intakes for recovery from stunting are available...
  42. ncbi Calcium absorption is not increased by caseinophosphopeptides
    Birgit Teucher
    Institute of Food Research, Norwich, United Kingdom
    Am J Clin Nutr 84:162-6. 2006
    ..This possibility is based on the assumption that they resist proteolysis in the upper gastrointestinal tract and maintain calcium in a soluble form at alkaline pH in the distal ileum...
  43. ncbi Neural tube defect rates before and after food fortification with folic acid
    James L Mills
    Division of Epidemiology, Statistics and Prevention Research, NICHD, NIH, HHS, Bethesda, Maryland 20892, USA
    Birth Defects Res A Clin Mol Teratol 70:844-5. 2004
    ..However, accurate determination of NTD rates requires counting antenatally detected cases; the CDC study noted that the number of prenatally diagnosed cases was likely underestimated...
  44. ncbi Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2000
    Christine M Pfeiffer
    National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Clin Nutr 82:442-50. 2005
    ..Mandatory folic acid fortification of cereal-grain products was introduced in the United States in 1998 to decrease the risk that women will have children with neural tube defects...
  45. pmc Effects of fortified milk on morbidity in young children in north India: community based, randomised, double masked placebo controlled trial
    Sunil Sazawal
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    BMJ 334:140. 2007
    ..To evaluate the efficacy of milk fortified with specific multiple micronutrients on morbidity in children compared with the same milk without fortification...
  46. ncbi Will mandatory folic acid fortification prevent or promote cancer?
    Young In Kim
    Department of Medicine and Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    Am J Clin Nutr 80:1123-8. 2004
    ..The potential cancer-promoting effect of folic acid supplementation needs to be considered in carefully monitoring the long-term effect of folic acid fortification on the vast majority of the US population, who are not at risk of NTDs...
  47. ncbi Wheat flour fortification is unlikely to benefit the neediest in Guatemala
    Beth Imhoff-Kunsch
    Nutrition and Health Sciences Program, Emory University, Atlanta, GA, USA
    J Nutr 137:1017-22. 2007
    ..The poorest, rural, indigenous populations who suffer the highest burden of nutritional deficiencies likely benefit least from wheat flour fortification...
  48. ncbi Enhancing the absorption of fortification iron. A SUSTAIN Task Force report
    Richard F Hurrell
    Laboratory for Human Nutrition, Swiss Federal Institute of Technology Zurich, Ruschlikon, Switzerland
    Int J Vitam Nutr Res 74:387-401. 2004
    ..An approach to the calculation of cost using a conservative estimate of the enhancing effects of the innovative technologies discussed in the supplement is given in the final section...
  49. ncbi Should calcium and vitamin D be added to the current enrichment program for cereal-grain products?
    Harold L Newmark
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
    Am J Clin Nutr 80:264-70. 2004
    ..We suggest a full scientific review of cereal-grain enrichment with calcium and vitamin D...
  50. ncbi Trend in prevalence of neural tube defects in Quebec
    Philippe De Wals
    Departement de Medecine sociale et preventive, Universite Laval, Quebec, Canada
    Birth Defects Res A Clin Mol Teratol 67:919-23. 2003
    ..In 1998, fortification of flour with FA became mandatory. The objective of this study was to assess the impact of these measures on the prevalence of neural tube defects (NTDs) in the province of Quebec...
  51. ncbi Effect of food fortification on folic acid intake in the United States
    Eoin P Quinlivan
    Food Science and Human Nutrition Department, University of Florida, Gainesville, USA
    Am J Clin Nutr 77:221-5. 2003
    ....
  52. ncbi Feeding patterns of underweight children in rural Malawi given supplementary fortified spread at home
    Valerie L Flax
    School of Public Health, Tampere University, Tampere, Finland
    Matern Child Nutr 4:65-73. 2008
    ..To limit wastage, caregivers should be advised to serve FS plain or to mix it with only a small quantity of porridge...
  53. ncbi Home fortification of complementary foods with micronutrient supplements is well accepted and has positive effects on infant iron status in Ghana
    Seth Adu-Afarwuah
    Program in International and Community Nutrition, University of California, Davis, CA 95616 8669, USA
    Am J Clin Nutr 87:929-38. 2008
    ..Micronutrient deficiencies are common during infancy, and optimal approaches for their prevention need to be identified...
  54. ncbi Randomized efficacy trial of a micronutrient-fortified beverage in primary school children in Tanzania
    Deborah M Ash
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    Am J Clin Nutr 77:891-8. 2003
    ..Dietary supplements providing physiologic amounts of several micronutrients simultaneously have not been thoroughly tested for combating micronutrient deficiencies...
  55. ncbi Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects
    M A Honein
    National Center on Birth Defects and Developmental Disabilities, Mailstop F 45, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Atlanta, GA 30341 3724, USA
    JAMA 285:2981-6. 2001
    ..The US Food and Drug Administration authorized addition of folic acid to enriched grain products in March 1996, with compliance mandatory by January 1998...
  56. ncbi Sustainable universal salt iodization in low-income countries - time to re-think strategies?
    V D Assey
    IDD Control Program, Tanzania Food and Nutrition Centre TFNC, Dar es Salaam, Tanzania
    Eur J Clin Nutr 62:292-4. 2008
    ..Sustained iodine deficiency control requires sustainable mechanisms for iodine supplementation. We aim to describe the status of salt iodation machines, salt producers' experiences and quality of salt produced in Tanzania...
  57. ncbi Zinc and iron nutrition in Chilean children fed fortified milk provided by the Complementary National Food Program
    Claudia S Torrejón
    Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Santiago, Chile
    Nutrition 20:177-80. 2004
    ..5 mg/L) to be provided to infants until age 18 mo and to pregnant women. We analyzed the nutrition status of zinc and iron at age 18 mo in infants who consumed the fortified cow's milk...
  58. pmc Iron fortified follow on formula from 9 to 18 months improves iron status but not development or growth: a randomised trial
    R Morley
    Menzies Centre for Population Health Research, Tasmania and Clinical Epidemiology and Biostatistics Unit, University of Melbourne Department of Paediatrics, Royal Children s Hospital, Parkville, VIC 3052, Australia
    Arch Dis Child 81:247-52. 1999
    ..Iron deficiency anaemia is associated, in observational studies, with developmental disadvantage. This study tested the hypothesis that feeding iron supplemented formula from 9 to 18 months of age would improve developmental performance...
  59. ncbi Supplementary feeding of underweight, stunted Malawian children with a ready-to-use food
    Kenneth Maleta
    College of Medicine, University of Malawi, Blantyre, Malawi
    J Pediatr Gastroenterol Nutr 38:152-8. 2004
    ..The authors compared the effect of maize and soy flour with that of RTUF in the home treatment of moderately malnourished children...
  60. ncbi Recent experience with fortification of foods and beverages with iron for the control of iron-deficiency anemia in Brazilian children
    Mark Anthony Beinner
    Department of Health Sciences, University of Brasilia, Brazil
    Food Nutr Bull 24:268-74. 2003
    ..A review of the available reports from experience in Brazil with iron fortification of foods and liquids is presented...
  61. ncbi Colon cancer in Chile before and after the start of the flour fortification program with folic acid
    Sandra Hirsch
    Aging and chronic diseases program, INTA, University of Chile, Santiago, Chile
    Eur J Gastroenterol Hepatol 21:436-9. 2009
    ..A temporal association between folic acid fortification of enriched cereal grains and an increase in the incidence of colorectal cancer in the USA and Canada has, however, been recently reported...
  62. ncbi Interactive effects of iron and zinc on biochemical and functional outcomes in supplementation trials
    Christa Fischer Walker
    Bloomberg School of Public Health, Department of International Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Clin Nutr 82:5-12. 2005
    ..Further research is needed before health policies on joint supplementation programs can be established...
  63. ncbi Decline in the prevalence of spina bifida and anencephaly by race/ethnicity: 1995-2002
    Laura J Williams
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Pediatrics 116:580-6. 2005
    ..We sought to characterize the decline in the prevalence of spina bifida and anencephaly among specific racial/ethnic groups during the transition to mandatory folic acid fortification in the United States...
  64. ncbi Optimizing bone health and calcium intakes of infants, children, and adolescents
    Frank R Greer
    Pediatrics 117:578-85. 2006
    ..Establishing these practices in childhood is important so that they will be followed throughout the life span...
  65. ncbi Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States
    Laura J Williams
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Teratology 66:33-9. 2002
    ..We sought to determine the prevalences of spina bifida and anencephaly during the transition to mandatory folic acid fortification...
  66. ncbi The use of novel foods enriched with long-chain n-3 fatty acids to increase dietary intake: a comparison of methodologies assessing nutrient intake
    Craig S Patch
    National Centre of Excellence in Functional Foods, University of Wollongong, New South Wales, Australia
    J Am Diet Assoc 105:1918-26. 2005
    ..To evaluate the effect of consuming a variety of foods enriched in long-chain n-3 fatty acids in low fish eaters...
  67. ncbi Supplemental feeding with ready-to-use therapeutic food in Malawian children at risk of malnutrition
    Monica P Patel
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Health Popul Nutr 23:351-7. 2005
    ..The results of this preliminary work suggest that supplementary feeding with RUTF promotes better growth in children at risk of malnutrition than the standard fortified cereal/legume-blended food...
  68. ncbi The effects of eicosapentaenoic acid-fortified food on inflammatory markers in healthy subjects--A randomized, placebo-controlled, double-blind study
    Shuntaro Fujioka
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama 930 0194, Japan
    J Nutr Sci Vitaminol (Tokyo) 52:261-5. 2006
    ..68%). The inflammatory markers did not change in either group. It is likely that fish oil does not change hs-CRP or sTNF-Rs 1 or 2 in subjects without active inflammation...
  69. ncbi Comparison of home-based therapy with ready-to-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: a controlled, clinical effectiveness trial
    Michael A Ciliberto
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA
    Am J Clin Nutr 81:864-70. 2005
    ..Higher recovery rates have been seen in pilot studies of home-based therapy with ready-to-use therapeutic food (RUTF)...
  70. ncbi Effect of micronutrient supplement on health and nutritional status of schoolchildren: biochemical status
    Battiprolu Sivakumar
    Division of Biophysics, National Institute of Nutrition Indian Council of Medical Research, Hyderabad, India
    Nutrition 22:S15-25. 2006
    ..We assessed the effect of a daily intake of a micronutrient-fortified beverage for 14 mo on indicators of biochemical status of important micronutrients in schoolchildren...
  71. ncbi Fortified complementary foods with or without alpha-amylase treatment increase hemoglobin but do not reduce breast milk intake of 9-mo-old Zambian infants
    Victor O Owino
    Center for International Child Health, Institute of Child Health, London, United Kingdom
    Am J Clin Nutr 86:1094-103. 2007
    ..Malnutrition in late infancy in developing countries may result from poor-quality complementary foods that displace breast milk...
  72. ncbi Bioequivalence of Docosahexaenoic acid from different algal oils in capsules and in a DHA-fortified food
    Linda M Arterburn
    Martek Biosciences Corporation, 6480 Dobbin Road, Columbia, MD 21045, USA
    Lipids 42:1011-24. 2007
    ..of DHA oils in capsules from two different algal strains versus bioavailability from an algal-DHA-fortified food. Our 28-day randomized, placebo-controlled, parallel group study compared bioavailability of (a) two different ..
  73. ncbi Folate content in commercial white and whole wheat sandwich breads
    Kelley E Johnston
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Agric Food Chem 52:6338-40. 2004
    ..These percentages were markedly higher than those in 2001. Our data suggest that folic acid in breads containing enriched flour declined after 2001 and monitoring of fortification may be necessary...
  74. ncbi Prevalence of neural tube defects, folate status, and folate fortification of enriched cereal-grain products in the United States
    Jeanne I Rader
    Office of Nutritional Products, Labeling and Dietary Supplements, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, MD 20740, USA
    Pediatrics 117:1394-9. 2006
  75. ncbi Sources of folate and serum folate levels in older adults
    Jessica E Mulligan
    Department of Nutrition and Food Sciences, Univeristy of Rhode Island, Kingston, RI 02881, USA
    J Am Diet Assoc 107:495-9. 2007
    ..However, older adults may be at risk for excess folic acid intake if they consume both a supplement and fortified cereals...
  76. ncbi Efficacy of Canadian folic acid food fortification
    Joel G Ray
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Food Nutr Bull 29:S225-30. 2008
    ..The current paper describes how this took place, and the epidemiological effects that occurred in the Canadian population, including higher blood folate levels and a decline in the prevalence of neural tube defects...
  77. ncbi Harmonization of nutrient intake values
    Janet C King
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Food Nutr Bull 28:S3-12. 2007
    ..Some examples include regulatory issues and trade, labeling, planning programs for alleviating public health nutrition problems, food fortification, and dietary guidance...
  78. ncbi Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: findings from the National Health and Nutrition Examination Survey, 2001-2002
    Quan He Yang
    Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Clin Nutr 85:1409-16. 2007
    ..Neural tube defects are serious birth defects of the brain and spinal cord. Up to 70% of neural tube defects can be prevented by the consumption of folic acid by women before and early during pregnancy...
  79. ncbi Reduced folate status is common and increases disease risk. It can be corrected by daily ingestion of supplements or fortification
    John M Scott
    School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland
    Novartis Found Symp 282:105-17; discussion 117-22, 212-8. 2007
    ..The level for such fortification is suboptimal for NTD prevention, because of fear of overexposure in the elderly. Thus even fortified communities require advice to take supplements for optimum NTD prevention...
  80. ncbi The folate debate
    Robert L Brent
    Department of Pediatrics, Radiology, and Pathology, Thomas Jefferson University, A I duPont Hospital for Children, Wilmington, Delaware, USA
    Pediatrics 117:1418-9. 2006
  81. ncbi To B or not to B? Interview by Angela Foster
    Gail Johnson
    Nurs Stand 22:21. 2008
    ..Increasing evidence of the important role of folic acid in pregnancy has led to further calls for the mandatory fortification of foods such as bread and flour. But not everyone is convinced...
  82. ncbi Barriers to optimizing vitamin D3 intake for the elderly
    Robert P Heaney
    Creighton University, Omaha, NE 68178, USA
    J Nutr 136:1123-5. 2006
    ..The age-related decline in cutaneous input, taken together with the UL, creates a substantial barrier to the deployment of public health strategies to optimize vitamin D status in the elderly...
  83. ncbi Overview of the proceedings from Experimental Biology 2005 symposium: Optimizing Vitamin D Intake for Populations with Special Needs: Barriers to Effective Food Fortification and Supplementation
    Susan J Whiting
    College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5C9, Canada
    J Nutr 136:1114-6. 2006
  84. ncbi Calcium supplementation in clinical practice: a review of forms, doses, and indications
    Deborah A Straub
    Canyon Ranch, 10237 East Desert Flower Place, Tucson, AZ 85749, USA
    Nutr Clin Pract 22:286-96. 2007
    ..Renal calculi in most studies have not been associated with calcium supplementation. The risk of advanced and fatal prostate cancer has been associated with calcium intakes from food or supplements in amounts >1500 mg/d...
  85. ncbi Framework for intake simulation of functional ingredients
    Janneke Kloosterman
    National Institute for Public Health and the Environment, PO Box 1, 3720, BA Bilthoven, The Netherlands
    Public Health Nutr 11:279-87. 2008
    ..To create a general framework for the simulation of intakes from mandatory or voluntary fortification, which will make outcomes of simulation studies more comparable and give insight on uncertainties...
  86. ncbi Public health significance of supplementation or fortification of grain products with folic acid
    Jacob Selhub
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Food Nutr Bull 29:S173-6. 2008
  87. ncbi Folate and human reproduction
    Tsunenobu Tamura
    Department of Nutrition Sciences, University of Alabama at Birmingham, AL 35294, USA
    Am J Clin Nutr 83:993-1016. 2006
    ....
  88. ncbi A high prevalence of biochemical evidence of vitamin B12 or folate deficiency does not translate into a comparable prevalence of anemia
    Jack Metz
    Dorevitch Pathology, Australia
    Food Nutr Bull 29:S74-85. 2008
    ..There are numerous reports of the effect of folic acid fortification of food on tests of folate status, but only a single published report on the hematological response was found...
  89. ncbi Improved iron bioavailability in an oat-based beverage: the combined effect of citric acid addition, dephytinization and iron supplementation
    Huanmei Zhang
    Biomedical Nutrition, P O Box 124, Centre for Chemistry and Chemical Engineering, Lund University, 22100 Lund, Sweden
    Eur J Nutr 46:95-102. 2007
    ..Iron deficiency in children is a major worldwide nutritional problem. An oat beverage was developed for 1- to 3-year-old children and different treatments were used to improve the iron bioavailability...
  90. ncbi Will increasing folic acid in fortified grain products further reduce neural tube defects without causing harm?: consideration of the evidence
    Richard B Johnston
    Department of Pediatrics, University of Colorado School of Medicine and National Jewish Medical and Research Center, Denver, CO 80262, USA
    Pediatr Res 63:2-8. 2008
    ..The published data indicate that it is appropriate that the FDA conduct or commission a balanced analysis of the evidence by scientists who will act on that evidence to decide this important question...
  91. ncbi Malnutrition: supplements and food fortification in the older population
    Annette Dunne
    Cardiff, Wales
    Br J Community Nurs 12:494-9. 2007
    ..Failure to acknowledge the risks of malnutrition can seriously impact on morbidity and mortality rates...
  92. ncbi Food fortification with folic acid: has the other shoe dropped?
    Noel W Solomons
    Center for Studies of Sensory Impairment, Aging, and Metabolism, Guatemala City, Guatemala
    Nutr Rev 65:512-5. 2007
    ..However, a recent note of caution has been raised concerning a possible negative effect of mandatory FA fortification on the incidence of colorectal cancer...
  93. ncbi Folic acid fortification and supplementation--good for some but not so good for others
    Young In Kim
    Department of Medicine, University of Toronto, Toronto, Canada
    Nutr Rev 65:504-11. 2007
    ....
  94. ncbi Calcium fortificants: overview and strategies for improving calcium nutriture of the U.S. population
    K Rafferty
    Creighton Univ, Osteoporosis Research Center, 601 N 30th St, Suite 4820, Omaha, NE 68131, USA
    J Food Sci 72:R152-8. 2007
    ..As a consequence, each product must be explicitly tested to establish the degree to which its calcium is available to consumers...
  95. ncbi Mandatory folic acid fortification in Newfoundland and Labrador
    Barbara V Roebothan
    Deivision of Community Health, Memorial University, St John s, NL
    Can J Diet Pract Res 68:143-5. 2007
    ..The analyses were an attempt to estimate the amount of FA they would consume solely because of mandatory fortification of foods...
  96. ncbi Iron status in Swedish teenage girls: impact of low dietary iron bioavailability
    Michael Hoppe
    Department of Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    Nutrition 24:638-45. 2008
    ..We investigated iron intake and iron absorption in the ordinary diet of free-living individuals in relation to iron status and assessed iron requirements...
  97. ncbi Fortifying food in the field to boost nutrition: case studies from Afghanistan, Angola, and Zambia
    Tina van den Briel
    Food Nutr Bull 28:353-64. 2007
    ....
  98. ncbi N-3 fatty acids: food or supplements?
    Penny M Kris-Etherton
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Am Diet Assoc 108:1125-30. 2008
  99. ncbi Folate intake and food-related behaviors in nonpregnant, low-income women of childbearing age
    Emily R Cena
    Department of Nutrition and Food Services, University of California, San Francisco Medical Center, San Francisco, CA 94143 0212, USA
    J Am Diet Assoc 108:1364-8. 2008
    ..Nutrition education that includes information about folic acid may be one way to improve folate intake and other healthful food behaviors among low-income women of childbearing age...
  100. ncbi Community-level micronutrient fortification of a food supplement in India: a controlled trial in preschool children aged 36-66 mo
    Jessica L Varma
    Tufts University Friedman School of Nutrition Science and Policy, Boston, MA, USA
    Am J Clin Nutr 85:1127-33. 2007
    ..Children participating in the Integrated Child Development Service (ICDS) in India have high rates of iron and vitamin A deficiency...
  101. ncbi Are we ready for mandatory fortification with vitamin B-12?
    Helga Refsum
    Am J Clin Nutr 88:253-4. 2008

Research Grants63

  1. Effect of a sanitation &nutrition intervention on HIV-exposed infant health
    JEAN HAWES HUMPHREY; Fiscal Year: 2012
    ..testing PCR-positive at 6 months;improved feeding practices;and provision of Nutributter, a micronutrient fortified food)...
  2. Complementary feeding: a Global Network cluster randomized controlled trial
    K Michael Hambidge; Fiscal Year: 2012
    ..The broad goal of this proposal is to determine the multicultural potential of a non-fortified food-based approach (with continued breastfeeding), to achieve a nutritionally complete diet between 6-18 mo of age,..
  3. B12 Nutrition in the Aged
    Sally Stabler; Fiscal Year: 2007
    ..high serum total homocysteine) remains a problem for seniors even in this era of highly folate-fortified food in the United States...
  4. Psychophysics of Divalent Salts and Metallic Taste
    HARRY LAWLESS; Fiscal Year: 2006
    ..dietary calcium insufficiency is a growing concern and is being addressed by an increasing number of calcium fortified food products. Iron deficiency is a continuing problem in the third world, affecting billions of people worldwide...
  5. ISOFLAVONE-RICH PASTA--CLINICAL AND COMMERCIAL POTENTIAL
    RICHARDUS ROSS; Fiscal Year: 2000
    ..formulations and production operating parameters allowing the test manufacture of several soy isoflavone fortified food prototypes based on the ailmentary pasta format which will subsequently be chemically evaluated for isoflavone ..
  6. WHO MULTICENTER GROWTH REFERENCE STUDY: U.S. SITE
    Kathryn Dewey; Fiscal Year: 2002
    ..The data will be pooled by WHO to create a new growth reference, applicable to all infants and children internationally. ..
  7. Bone-Sparing by Ca Salts With & Without Extra Phosphorus
    Robert Heaney; Fiscal Year: 2008
    ..1 Description, ..
  8. BONY EFFECTS OF TRANSIENT NONSKELETAL ILLNESS
    Robert Heaney; Fiscal Year: 2001
    ....
  9. Effects of Folate Fortification on Cancer Prevention an*
    Chandrika Piyathilake; Fiscal Year: 2005
    ....
  10. Prognostic Significance of DNA and Histone Methylation
    Chandrika Piyathilake; Fiscal Year: 2007
    ..Investigator talent, equipment, facilities and access to study subjects at UAB are ideal for conducting this study. ..
  11. HPV Clearance by Folic Acid Supplementation
    Chandrika J Piyathilake; Fiscal Year: 2010
    ..Because this study will be conducted among women positive for HPV 16, the most prevalent and powerful causative agent of CC, the public health significance of this study could be enormous and will complement HPV vaccine studies. ..
  12. Prognostic Significance of Altered DNA Methylation
    Chandrika Piyathilake; Fiscal Year: 2002
    ..A newly developed and tested immunohistochemical technique, which measures the degree of global methylation in intact and specific types of cells, will be used to evaluate global DNA methylation in the proposed study. ..
  13. Zn & Maternal-Infant Brain Function in S. Ethiopia: Randomized Controlled Trials
    K Hambidge; Fiscal Year: 2009
    ....
  14. Renal Transplantation, Homocysteine Lowering & Cognition
    Irwin Rosenberg; Fiscal Year: 2007
    ..Demonstrating the cognitive benefits of lowering homocysteine may pave the way to nutritional modification of cognitive decline in RTRs and other high-risk groups and even in the general population. ..
  15. Micronutrients, stroke and cognition in aging
    Irwin Rosenberg; Fiscal Year: 2006
    ..abstract_text> ..
  16. RESEARCH TRAINING IN MATERNAL, INFANT & CHILD NUTRITION
    William Heird; Fiscal Year: 2008
    ..abstract_text> ..
  17. Calcium Absorption and Bone Formation During Puberty
    Steven Abrams; Fiscal Year: 2005
    ....
  18. Vitamin B12 and Folate in Relation to Cognition in the Framingham Offspring Study
    Jacob Selhub; Fiscal Year: 2010
    ..5 About 3-5 percent of seniors have low circulating vitamin B12 levels;6 however, about 20 percent of seniors are found to be deficient when those with elevated methylmalonic acid levels are included. ..
  19. THE PHOTOBIOLOGY OF VITAMIN D
    Michael Holick; Fiscal Year: 2005
    ..Results from this study should provide important new insights into the photoproduction of toxisterols and suprasterols in human skin and provide new information about their potential biologic functions in the skin. ..
  20. Impact of Development on Protein Utilization and Growth
    William Heird; Fiscal Year: 2007
    ..Overall, the findings of this project are expected to contribute to further improvements in nutritional management and, hence, outcome of LBW infants. ..
  21. DIETARY OMEGA-3 FATTY ACIDS, GENE EXPRESSION AND GROWTH
    William Heird; Fiscal Year: 2001
    ..abstract_text> ..
  22. Measurement of folate in fortified cereal grain products
    Jacob Selhub; Fiscal Year: 2003
    ..In order to assess the impact of folic acid fortification, it is necessary to have valid data on the actual synthetic folic acid content of fortified foods. ..
  23. FOOD FOLATE FORTIFICATION EFFECT ON FOLATE STATUS
    Jacob Selhub; Fiscal Year: 2001
    ..abstract_text> ..
  24. PTH (7-34) for Chemotherapy alopecia in Breast Cancer
    Michael Holick; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  25. MEASURING & DOCUMENTING DISPARITIES IN ORAL HEALTH: A PRACTICAL APPROACH
    Luisa Borrell; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  26. Exercise effects on oxidative damage among women
    Cornelia Ulrich; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  27. FATTY ACID MODULATION OF COLON CELL TRANSFORMATION
    Leonard Augenlicht; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  28. Coordination of Proliferation and Apoptosis
    Leonard Augenlicht; Fiscal Year: 2002
    ..Understanding the mechanism by which mitochondrial function coordinates cell maturation pathways in the intestinal mucosa has profound implications for understanding tumorigenesis and for effecting chemoprevention. ..
  29. IRON SUPPLEMENTS AND ZINC IN PREGNANCY AND LACTATION
    Janet King; Fiscal Year: 2001
    ..Results from this comprehensive, longitudinal study will provide new data on the effects of iron supplementation on zinc utilization during pregnancy and lactation. ..
  30. Nutritional mechanisms and intestinal tumorigenesis
    Leonard Augenlicht; Fiscal Year: 2009
    ....
  31. COLON CANCER--MOLECULAR BIOLOGY OF CELL RESPONSE TO DIET
    Leonard Augenlicht; Fiscal Year: 2001
    ....
  32. Dairy Foods and Blood Pressure in Multi-Ethnic Children
    Debra Sullivan; Fiscal Year: 2008
    ..If successful, this trial will illustrate a simple, minimal interventions strategy that can be easily disseminated and will diminish health risk in children. [unreadable] [unreadable] [unreadable]..
  33. Hepcidin and the pathogenesis of anemia in older adults.
    Richard D Semba; Fiscal Year: 2010
    ..This study should provide new insight into the epidemiology and biological mechanisms of anemia among older adults and help identify strategies aimed at the prevention and treatment of anemia. ..
  34. SIGNALING IN INTESTINAL CANCER
    Leonard H Augenlicht; Fiscal Year: 2010
    ..abstract_text> ..
  35. Homeostatic Regulation of Folate Metabolism
    Patrick J Stover; Fiscal Year: 2010
    ..5. regulation of cSHMT by folate/choline preserves dTMP pools at the expense of AdoMet synthesis. The long-term goals of this project are: 1. to define homeostatic mechanisms used bv cells to regulate folate metabolism. ..
  36. NSAID and COX/PG Metabolism and Colorectal Cancer
    Cornelia Ulrich; Fiscal Year: 2009
    ..Ultimately, such information on the metabolic variation will be useful in optimizing NSAIDs and NSAID regimens and will allow individual tailoring of chemoprevention. ..
  37. CURCUMIN--MECHANISMS OF CHEMOPREVENTION
    Leonard Augenlicht; Fiscal Year: 2001
    ..On the other hand, differences in mechanism could suggest a study design in which curcumin was combined with sulindac or to other NSAIDs in a prevention trial to test whether the two agents give additive, or synergistic, effects. ..
  38. DIET GLYCEMIC LOAD & METABOLISM IN OBESE PREGNANT WOMEN
    Janet King; Fiscal Year: 2009
    ..In addition, new information on how the source of maternal carbohydrate intake affects carbohydrate and lipid metabolism in pregnancy will be generated. ..
  39. NUTRITIONAL PROPERTIES OF PYRIDOXINE-BETA-GLUCOSIDE
    JESSE GREGORY; Fiscal Year: 2001
    ..These studies will provide new insight into the regulation of PNG hydrolase that is the rate-limiting enzyme for the utilization of glycosylated B6 in human diets. ..
  40. Genetic Study of Prostaglandin Synthesis/EGFR and Risk of Colorectal Neoplasia
    Cornelia Ulrich; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  41. Serum Total Homocysteine and C-Reactive Protein as Pred
    Andrew Bostom; Fiscal Year: 2002
    ....
  42. FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDY
    Maria Martinez; Fiscal Year: 2003
    ..C-peptide, glycosylated hemoglobin, IGF-1, and IGFBP3 will be evaluated with respect to breast and endometrial cancer in a subset of women. ..
  43. ADJUNCT VITAMIN A THERAPY FOR TUBERCULOSIS AND HIV/AIDS
    Richard Semba; Fiscal Year: 2005
    ....
  44. SITE SPECIFICITY OF GASTROINTESTINAL TUMORIGENESIS
    Leonard Augenlicht; Fiscal Year: 2004
    ..Lastly, using microarray analyses, the profiles of gene expression that characterize genetic and dietary modulation of risk will be defined. ..
  45. MOLECULAR CLASSIFICATION OF COLON TUMORS
    Leonard Augenlicht; Fiscal Year: 2004
    ..abstract_text> ..
  46. Role of 10-formyldihydrofolate in purine biosynthesis
    Tsunenobu Tamura; Fiscal Year: 2004
    ..If this pathway is proven, derivatives of 10-HCO-H2folate could be used to inhibit de novo purine biosynthesis for developing new anticancer drugs. ..
  47. DIETARY FAT, PLASMA LIPIDS AND OTHER CHD RISK FACTORS.
    Alice Lichtenstein; Fiscal Year: 2003
    ..The investigators state that data derived from the proposed studies could contribute to the database on which to formulate more specific public health recommendations regarding the variables described. ..
  48. Getting a Head Start on Healthier Eating Habits
    Theresa Nicklas; Fiscal Year: 2006
    ..g., role modeling, encouragement, repeated exposure) that would be used to reinforce the impact of the FJV commercials on children's FJV preferences and consumption in an ensuing R01 grant. ..
  49. CANCER DIET KNOWLEDGE AND BELIEFS IN AFRICAN AMERICANS
    ADELIA BOVELL BENJAMIN; Fiscal Year: 2003
    ..abstract_text> ..
  50. POLYMORPHISMS IN PG/COX PATHWAY AND COLORECTAL POLYPS
    Cornelia Ulrich; Fiscal Year: 2003
    ..Finally, we plan to develop a model for integrating information on genetic variability at multiple points in this metabolic pathway. ..
  51. GENE INTERACTIONS IN COLON CANCER
    Leonard Augenlicht; Fiscal Year: 2003
    ....
  52. Cholesterol Homeostasis in Framingham Offspring Study
    Alice Lichtenstein; Fiscal Year: 2006
    ..abstract_text> ..
  53. NUTRITIONAL BIOCHEMISTRY AND EPIDEMIOLOGY OF CANCER
    Steven Zeisel; Fiscal Year: 2006
    ..We are requesting two postdoctoral and six predoctoral trainee positions each year for this purpose. ..
  54. Predictors of Children's Serving Sizes & Mealtime Intake
    Theresa Nicklas; Fiscal Year: 2007
    ..Understanding what influences the portion sizes of energy dense foods and FV will provide insight on intervention strategies for decreasing excessive intake of energy dense foods and increasing FV intake early in childhood. ..
  55. Mammalian Lactoferrin Receptors: Structure and Function
    Bo Lonnerdal; Fiscal Year: 2007
    ..Overall, our understanding of the physiological significance of Lf and its receptor will be increased. ..
  56. FASEB Summer Conference: Folate, B12 and 1C Metabolism
    PATRICK STOVER; Fiscal Year: 2004
    ..Similarly, the poster sessions also highlight the activities and needs of the younger participants. ..
  57. SUBTLE DISTURBANCES OF COBALAMIN STATUS
    Ralph Carmel; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  58. Iron and the Breast-fed Infant
    Ekhard Ziegler; Fiscal Year: 2005
    ..We expect to find that infants re-excrete iron into the feces when their iron stores are full, but retain most of the absorbed iron when iron stores are low. ..
  59. Diethanolamine, brain development and adult memory
    Steven Zeisel; Fiscal Year: 2006
    ..abstract_text> ..
  60. Vitamin B6, Vascular Dysfunction and Adhesion Molecules in Sickle Cell Disease
    Ralph Green; Fiscal Year: 2010
    ..The positive health impact of vitamin supplementation that could ameliorate the high morbidity and mortality associated with this disorder has the potential for high benefit with minimal cost and risk. ..
  61. VITAMIN A SUPPLEMENTATION FOR HIV INFECTED CHILDREN
    Richard Semba; Fiscal Year: 2002
    ....
  62. Oxidative Stress and the Pathogenesis of Sarcopenia and Disability in Older Women
    Richard Semba; Fiscal Year: 2008
    ..AGEs are a potentially modifiable risk factor, as circulating AGEs can be lowered by dietary modification and by pharmacological intervention. ..
  63. Effect of diet on insulin sensitivity and energy balance
    NICHOLAS HAYS; Fiscal Year: 2005
    ..S. population, completion of this project will more clearly define the specific dietary and exercise interventions that have the greatest potential positive impact on health in older individuals. ..