fruit

Summary

Summary: The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.

Top Publications

  1. pmc An oligo-based microarray offers novel transcriptomic approaches for the analysis of pathogen resistance and fruit quality traits in melon (Cucumis melo L.)
    Albert Mascarell-Creus
    Molecular Genetics Department, Centre for Research in Agricultural Genomics CRAG CSIC IRTA UAB, Barcelona 08034, Spain
    BMC Genomics 10:467. 2009
  2. pmc Engineering melon plants with improved fruit shelf life using the TILLING approach
    Fatima Dahmani-Mardas
    Unite de Recherche en Genomique Vegetale, UMR1165 ERL8196 INRA UEVE CNRS, Evry, France
    PLoS ONE 5:e15776. 2010
  3. ncbi The genome of the domesticated apple (Malus × domestica Borkh.)
    Riccardo Velasco
    Istituto Agrario San Michele all Adige Research and Innovation Centre, Foundation Edmund Mach, Trento, Italy
    Nat Genet 42:833-9. 2010
  4. ncbi Loosening of plant cell walls by expansins
    D J Cosgrove
    Department of Biology, Pennsylvania State University, University Park 16802, USA
    Nature 407:321-6. 2000
  5. pmc The contextual effect of the local food environment on residents' diets: the atherosclerosis risk in communities study
    Kimberly Morland
    Department of Epidemiology, University of North Carolina, Chapel Hill, USA
    Am J Public Health 92:1761-7. 2002
  6. ncbi A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening
    Kenneth Manning
    Warwick Horticulture Research International HRI, University of Warwick, Wellesbourne, Warwick CV35 9EF, UK
    Nat Genet 38:948-52. 2006
  7. pmc Tissue- and cell-type specific transcriptome profiling of expanding tomato fruit provides insights into metabolic and regulatory specialization and cuticle formation
    Antonio J Matas
    Department of Plant Biology, Cornell University, Ithaca, New York 14853, USA
    Plant Cell 23:3893-910. 2011
  8. pmc Deep sequencing of tomato short RNAs identifies microRNAs targeting genes involved in fruit ripening
    Simon Moxon
    School of Computing, University of East Anglia, Norwich NR4 7TJ, United Kingdom
    Genome Res 18:1602-9. 2008
  9. pmc Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development
    Laurent G Deluc
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557 0014, USA
    BMC Genomics 8:429. 2007
  10. pmc Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development
    Fiammetta Alagna
    CNR Institute of Plant Genetics, Via Madonna Alta 130, 06128 Perugia, Italy
    BMC Genomics 10:399. 2009

Detail Information

Publications351 found, 100 shown here

  1. pmc An oligo-based microarray offers novel transcriptomic approaches for the analysis of pathogen resistance and fruit quality traits in melon (Cucumis melo L.)
    Albert Mascarell-Creus
    Molecular Genetics Department, Centre for Research in Agricultural Genomics CRAG CSIC IRTA UAB, Barcelona 08034, Spain
    BMC Genomics 10:467. 2009
    ..However, the unprecedented existence of a transcriptomic approaches in melon, highlight the importance of designing new tools for high-throughput analysis of gene expression...
  2. pmc Engineering melon plants with improved fruit shelf life using the TILLING approach
    Fatima Dahmani-Mardas
    Unite de Recherche en Genomique Vegetale, UMR1165 ERL8196 INRA UEVE CNRS, Evry, France
    PLoS ONE 5:e15776. 2010
    b>Fruit ripening and softening are key traits that have an effect on food supply, fruit nutritional value and consequently, human health...
  3. ncbi The genome of the domesticated apple (Malus × domestica Borkh.)
    Riccardo Velasco
    Istituto Agrario San Michele all Adige Research and Innovation Centre, Foundation Edmund Mach, Trento, Italy
    Nat Genet 42:833-9. 2010
    ..sieversii. Expansion of gene families reported to be involved in fruit development may explain formation of the pome, a Pyreae-specific false fruit that develops by proliferation of the ..
  4. ncbi Loosening of plant cell walls by expansins
    D J Cosgrove
    Department of Biology, Pennsylvania State University, University Park 16802, USA
    Nature 407:321-6. 2000
    ..Expansin's action has puzzling implications for plant cell-wall structure. The recent explosion of gene sequences and expression data has given new hints of additional biological functions for expansins...
  5. pmc The contextual effect of the local food environment on residents' diets: the atherosclerosis risk in communities study
    Kimberly Morland
    Department of Epidemiology, University of North Carolina, Chapel Hill, USA
    Am J Public Health 92:1761-7. 2002
    ..We studied the association between the local food environment and residents' report of recommended dietary intake...
  6. ncbi A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening
    Kenneth Manning
    Warwick Horticulture Research International HRI, University of Warwick, Wellesbourne, Warwick CV35 9EF, UK
    Nat Genet 38:948-52. 2006
    A major component in the regulatory network controlling fruit ripening is likely to be the gene at the tomato Colorless non-ripening (Cnr) locus...
  7. pmc Tissue- and cell-type specific transcriptome profiling of expanding tomato fruit provides insights into metabolic and regulatory specialization and cuticle formation
    Antonio J Matas
    Department of Plant Biology, Cornell University, Ithaca, New York 14853, USA
    Plant Cell 23:3893-910. 2011
    ..is the primary model for the study of fleshy fruits, and research in this species has elucidated many aspects of fruit physiology, development, and metabolism...
  8. pmc Deep sequencing of tomato short RNAs identifies microRNAs targeting genes involved in fruit ripening
    Simon Moxon
    School of Computing, University of East Anglia, Norwich NR4 7TJ, United Kingdom
    Genome Res 18:1602-9. 2008
    ..used high-throughput pyrosequencing to identify conserved and nonconserved miRNAs and other short RNAs in tomato fruit and leaf...
  9. pmc Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development
    Laurent G Deluc
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557 0014, USA
    BMC Genomics 8:429. 2007
    ....
  10. pmc Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development
    Fiammetta Alagna
    CNR Institute of Plant Genetics, Via Madonna Alta 130, 06128 Perugia, Italy
    BMC Genomics 10:399. 2009
    ..454 pyrosequencing was used to enrich the very few sequence data currently available for the Olea europaea species and to identify genes involved in expression of fruit quality traits.
  11. pmc Transcriptomic analysis of Chinese bayberry (Myrica rubra) fruit development and ripening using RNA-Seq
    Chao Feng
    Laboratory of Fruit Quality Biology The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang University, Hangzhou 310058, PR China
    BMC Genomics 13:19. 2012
    Chinese bayberry (Myrica rubra Sieb. and Zucc.) is an important subtropical fruit crop and an ideal species for fruit quality research due to the rapid and substantial changes that occur during development and ripening, including changes ..
  12. pmc Red colouration in apple fruit is due to the activity of the MYB transcription factor, MdMYB10
    Richard V Espley
    HortResearch, Mt Albert Research Centre, Private Bag 92169, Auckland, New Zealand
    Plant J 49:414-27. 2007
    ..The apple fruit cortex is usually colourless, although germplasm does exist where the cortex is highly pigmented due to the ..
  13. pmc Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis
    Patrice Carter
    Diabetes Research, Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 5WW
    BMJ 341:c4229. 2010
    To investigate the independent effects of intake of fruit and vegetables on incidence of type 2 diabetes.
  14. ncbi Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies
    Luc Dauchet
    INSERM U557, INRA U1125, CNAM, University Paris 13, Centre de Recherche en Nutrition Humaine, 93017 Bobigny, France
    J Nutr 136:2588-93. 2006
    The consumption of fruit and vegetables is associated with a reduced rate of coronary heart disease (CHD) in observational cohorts. The purpose of this study was to assess the strength of this association in a meta-analysis...
  15. pmc The global burden of disease attributable to low consumption of fruit and vegetables: implications for the global strategy on diet
    Karen Lock
    European Centre on Health of Societies in Transition, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
    Bull World Health Organ 83:100-8. 2005
    We estimated the global burden of disease attributable to low consumption of fruit and vegetables, an increasingly recognized risk factor for cardiovascular disease and cancer, and compared its impact with that of other major risk ..
  16. ncbi Validation of reference genes for RT-qPCR studies of gene expression in banana fruit under different experimental conditions
    Lei Chen
    Guangdong Key Laboratory for Postharvest Science, College of Horticultural Science, South China Agricultural University, Guangzhou, 510642, People s Republic of China
    Planta 234:377-90. 2011
    ..Only a few studies on validation of reference genes have been conducted in fruit trees and none in banana yet...
  17. pmc A SEPALLATA gene is involved in the development and ripening of strawberry (Fragaria x ananassa Duch.) fruit, a non-climacteric tissue
    Graham B Seymour
    Division of Plant and Crop Sciences, University of Nottingham, School of Biosciences, Sutton Bonington Campus, Loughborough, Leics LE12 5RD, UK
    J Exp Bot 62:1179-88. 2011
    ..It has been demonstrated here that silencing a fruit-related SEP1/2-like (FaMADS9) gene in strawberry leads to the inhibition of normal development and ripening in the ..
  18. ncbi Food store types, availability, and cost of foods in a rural environment
    Angela D Liese
    Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
    J Am Diet Assoc 107:1916-23. 2007
    ..To characterize the built nutritional environment in terms of types and number of food stores, availability, and cost of selected food items in a rural area...
  19. pmc Comparative transcriptome and metabolite analysis of oil palm and date palm mesocarp that differ dramatically in carbon partitioning
    Fabienne Bourgis
    Université de Bordeaux Ségalen, Laboratoire de Biogenese Membranaire, Bordeaux, France
    Proc Natl Acad Sci U S A 108:12527-32. 2011
    ....
  20. ncbi Fruit and vegetable consumption and stroke: meta-analysis of cohort studies
    Feng J He
    Blood Pressure Unit, Cardiac and Vascular Sciences, St George s University of London, London, UK
    Lancet 367:320-6. 2006
    Increased consumption of fruit and vegetables has been shown to be associated with a reduced risk of stroke in most epidemiological studies, although the extent of the association is uncertain...
  21. pmc Americans do not meet federal dietary recommendations
    Susan M Krebs-Smith
    National Cancer Institute, Bethesda, MD 20892, USA
    J Nutr 140:1832-8. 2010
    ..In conclusion, nearly the entire U.S. population consumes a diet that is not on par with recommendations. These findings add another piece to the rather disturbing picture that is emerging of a nation's diet in crisis...
  22. ncbi Genetics and control of tomato fruit ripening and quality attributes
    Harry J Klee
    University of Florida, Horticultural Sciences, Gainesville, Florida 32611, USA
    Annu Rev Genet 45:41-59. 2011
    ..Regulated expression of thousands of genes controls fruit softening as well as accumulation of pigments, sugars, acids, and volatile compounds that increase attraction to ..
  23. ncbi Ethylene biosynthesis and action in tomato: a model for climacteric fruit ripening
    Lucille Alexander
    Plant Science Division, School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK
    J Exp Bot 53:2039-55. 2002
    Elucidating the mechanisms involved in ripening of climacteric fruit and the role that ethylene plays in the process are key to understanding fruit production and quality...
  24. ncbi Fruit and vegetable intake in relation to risk of ischemic stroke
    K J Joshipura
    Department of Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    JAMA 282:1233-9. 1999
    Few studies have evaluated the relationship between fruit and vegetable intake and cardiovascular disease.
  25. ncbi Global variability in fruit and vegetable consumption
    Justin N Hall
    School of Kinesiology and Health Studies, Queen s University, Kingston, Ontario, Canada
    Am J Prev Med 36:402-409.e5. 2009
    Low fruit and vegetable consumption is an important risk factor for chronic diseases, but for many (mainly developing) countries, no prevalence data have ever been published...
  26. ncbi A MADS-box gene necessary for fruit ripening at the tomato ripening-inhibitor (rin) locus
    Julia Vrebalov
    U S Department of Agriculture Agricultural Research Service USDA ARS Plant, Soil and Nutrition Lab and Boyce Thompson Institute for Plant Research, Cornell University, Ithaca, NY 14853, USA
    Science 296:343-6. 2002
    ..locus revealed two tandem MADS-box genes (LeMADS-RIN and LeMADS-MC), whose expression patterns suggested roles in fruit ripening and sepal development, respectively. The rin mutation alters expression of both genes...
  27. pmc The grapevine R2R3-MYB transcription factor VvMYBF1 regulates flavonol synthesis in developing grape berries
    Stefan Czemmel
    Heidelberger Institut für Pflanzenwissenschaften, 69120 Heidelberg, Germany
    Plant Physiol 151:1513-30. 2009
    ..To study the regulation of flavonol synthesis in fruit, we isolated and characterized the grapevine (Vitis vinifera 'Shiraz') R2R3-MYB transcription factor VvMYBF1...
  28. pmc Genome-wide transcriptional analysis of grapevine berry ripening reveals a set of genes similarly modulated during three seasons and the occurrence of an oxidative burst at vèraison
    Stefania Pilati
    Department of Genetics and Molecular Biology IASMA Research Center, Via E, Mach 1, 38010 S, Michele a Adige TN, Italy
    BMC Genomics 8:428. 2007
    Grapevine (Vitis species) is among the most important fruit crops in terms of cultivated area and economic impact...
  29. pmc Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay
    Laurent G Deluc
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NV 89557, USA
    BMC Genomics 10:212. 2009
    ..While some pathways or enzymes affected by water deficit have been identified, little is known about the global effects of water deficit on grape berry metabolism...
  30. ncbi Increasing caloric contribution from sugar-sweetened beverages and 100% fruit juices among US children and adolescents, 1988-2004
    Y Claire Wang
    Columbia Mailman School of Public Health, Department of Health Policy and Management, 600 West 168th St, 6th Floor, New York, NY 10032, USA
    Pediatrics 121:e1604-14. 2008
    We sought to document increases in caloric contributions from sugar-sweetened beverages and 100% fruit juice among US youth during 1988-2004.
  31. ncbi What can intervention studies tell us about the relationship between fruit and vegetable consumption and weight management?
    Barbara J Rolls
    The Pennsylvania State University, Department of Nutritional Sciences, 226 Henderson Building, University Park, PA 16802 6501, USA
    Nutr Rev 62:1-17. 2004
    ..Although few interventions have specifically addressed fruit and vegetable consumption, evidence suggests that coupling advice to increase intake of these foods with advice to ..
  32. ncbi The strawberry FaMYB1 transcription factor suppresses anthocyanin and flavonol accumulation in transgenic tobacco
    A Aharoni
    Business Unit Cell Cybernetics, Plant Research International, PO Box 16, 6700 AA Wageningen, The Netherlands
    Plant J 28:319-32. 2001
    b>Fruit ripening is characterized by dramatic changes in gene expression, enzymatic activities and metabolism...
  33. ncbi Ripening of fleshy fruit: molecular insight and the role of ethylene
    Vishwas A Bapat
    Department of Biotechnology, Shivaji University, Kolhapur 416 004, India
    Biotechnol Adv 28:94-107. 2010
    Development and ripening in fruit is a unique phase in the life cycle of higher plants which encompasses several stages progressively such as fruit development, its maturation, ripening and finally senescence...
  34. ncbi Effect of post-harvest heat treatment on proteome change of peach fruit during ripening
    Li Zhang
    College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China
    J Proteomics 74:1135-49. 2011
    The extracted proteins from the heat-treated peach fruit (dipped in hot water at 48°C for 10min and then stored at room temperature (20°C-25°C) for up to 6 days) were used for proteomic analysis in order to understand the response of ..
  35. ncbi Profiling of short RNAs during fleshy fruit development reveals stage-specific sRNAome expression patterns
    Irina Mohorianu
    School of Computing Sciences, University of East Anglia, Norwich, UK
    Plant J 67:232-46. 2011
    ..of sRNA expression that often coincide with stages of the developmental process such as flowering, early and late fruit maturation...
  36. ncbi Combined transcription factor profiling, microarray analysis and metabolite profiling reveals the transcriptional control of metabolic shifts occurring during tomato fruit development
    Johannes Rohrmann
    Max Planck Institute of Molecular Plant Physiology, Am Muehlenberg 1, D 14476 Potsdam, Germany
    Plant J 68:999-1013. 2011
    ..We applied these platforms to pericarp material harvested throughout fruit development, studying both wild-type Solanum lycopersicum cv. Ailsa Craig and the hp1 mutant...
  37. pmc Reciprocity between abscisic acid and ethylene at the onset of berry ripening and after harvest
    Liang Sun
    College of Agronomy and Biotechnology, China Agricultural University, Yuanmingyuan West Road, Beijing, PR China
    BMC Plant Biol 10:257. 2010
    ..However, functional interaction and synergism between ABA and ethylene during the beginning of grape berry ripening (véraison) has been found recently...
  38. ncbi A retrotransposon-mediated gene duplication underlies morphological variation of tomato fruit
    Han Xiao
    Department of Horticulture and Crop Science, Ohio State University Ohio Agricultural Research and Development Center, Wooster, OH 44691, USA
    Science 319:1527-30. 2008
    ..SUN, one of the major genes controlling the elongated fruit shape of tomato, was positionally cloned and found to encode a member of the IQ67 domain-containing family...
  39. ncbi Family correlates of fruit and vegetable consumption in children and adolescents: a systematic review
    Natalie Pearson
    School of Sport and Exercise Sciences, Loughborough University, Loughborough, Leicestershire LE11 3TU, UK
    Public Health Nutr 12:267-83. 2009
    To review associations between the family environment and young people's fruit and vegetable consumption.
  40. ncbi Neighbourhood food environment and area deprivation: spatial accessibility to grocery stores selling fresh fruit and vegetables in urban and rural settings
    Dianna M Smith
    Healthy Environments Research Programme, Department of Geography, Queen Mary University of London, London, UK
    Int J Epidemiol 39:277-84. 2010
    ..This paper presents results from a study that quantified access to grocery stores selling fresh fruit and vegetables in four environmental settings in Scotland, UK.
  41. ncbi Higher fat intake and lower fruit and vegetables intakes are associated with greater acculturation among Mexicans living in Washington State
    Marian L Neuhouser
    Cancer Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Am Diet Assoc 104:51-7. 2004
    ..To examine associations of diet with acculturation among Hispanic immigrants from Mexico to Washington state and to compare dietary patterns of Hispanic with non-Hispanic white residents...
  42. pmc Proanthocyanidin synthesis and expression of genes encoding leucoanthocyanidin reductase and anthocyanidin reductase in developing grape berries and grapevine leaves
    Jochen Bogs
    Commonwealth Scientific and Industrial Research Organization, Plant Industry, Horticulture Unit, Glen Osmond, South Australia
    Plant Physiol 139:652-63. 2005
    ..Grape flowers had high levels of PA, and accumulation continued in skin and seeds from fruit set until the onset of ripening...
  43. ncbi Sequestration of auxin by the indole-3-acetic acid-amido synthetase GH3-1 in grape berry (Vitis vinifera L.) and the proposed role of auxin conjugation during ripening
    Christine Böttcher
    CSIRO Plant Industry, PO Box 350, Glen Osmond, SA 5064, Australia
    J Exp Bot 61:3615-25. 2010
    In fleshy fruit, levels of indole-3-acetic acid (IAA), the most abundant auxin, decline towards the onset of ripening. The application of auxins to immature fruit can delay the ripening processes...
  44. pmc The grapevine transcription factor VvMYBPA1 regulates proanthocyanidin synthesis during fruit development
    Jochen Bogs
    Commonwealth Scientific and Industrial Research Organization Plant Industry, Glen Osmond, 5064, Australia
    Plant Physiol 143:1347-61. 2007
    ..To our knowledge, this is the first report of a MYB factor that controls genes of the PA pathway in fruit, including both LAR and ANR, and this single MYB factor can induce ectopic PA accumulation in Arabidopsis.
  45. ncbi Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals
    Rui Hai Liu
    Department of Food Science and the Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, NY 14853, USA
    Am J Clin Nutr 78:517S-520S. 2003
    ..Regular consumption of fruit and vegetables is associated with reduced risks of cancer, cardiovascular disease, stroke, Alzheimer disease, ..
  46. pmc The role of ethylene and cold temperature in the regulation of the apple POLYGALACTURONASE1 gene and fruit softening
    Emma Tacken
    New Zealand Institute of Plant and Food Research, Auckland 1142, New Zealand
    Plant Physiol 153:294-305. 2010
    b>Fruit softening in apple (Malus x domestica) is associated with an increase in the ripening hormone ethylene...
  47. ncbi Neighbourhood fruit and vegetable availability and consumption: the role of small food stores in an urban environment
    J Nicholas Bodor
    Department of Community Health Sciences, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2301, New Orleans, LA 70112, USA
    Public Health Nutr 11:413-20. 2008
    ..This study synthesises both types of information - store access and in-store availability - to determine their potential relationship to fruit and vegetable consumption.
  48. ncbi Fresh fruit and vegetables as vehicles for the transmission of human pathogens
    Cedric N Berger
    Centre for Molecular Microbiology and Infection, Division of Cell and Molecular Biology, Imperial College London, London SW7 2AZ, UK
    Environ Microbiol 12:2385-97. 2010
    ....
  49. ncbi The Solanum lycopersicum auxin response factor 7 (SlARF7) regulates auxin signaling during tomato fruit set and development
    Maaike de Jong
    Department of Plant Cell Biology, Institute for Water and Wetland Research, Radboud University Nijmegen, Heyendaalseweg 135, Nijmegen, The Netherlands
    Plant J 57:160-70. 2009
    ..The expression analysis, together with the parthenocarpic fruit phenotype of the transgenic lines, suggests that, in tomato, SlARF7 acts as a negative regulator of fruit set ..
  50. pmc Global gene expression analysis of apple fruit development from the floral bud to ripe fruit
    Bart J Janssen
    The Horticulture and Food Research Institute of New Zealand Ltd, Mt Albert, Private Bag 92169, Auckland Mail Centre, Auckland 1142, New Zealand
    BMC Plant Biol 8:16. 2008
    Apple fruit develop over a period of 150 days from anthesis to fully ripe...
  51. ncbi Changes in tomato ovary transcriptome demonstrate complex hormonal regulation of fruit set
    Wim H Vriezen
    Department of Plant Cell Biology, Radboud University Nijmegen, Toernooiveld 1, 6525ED Nijmegen, The Netherlands
    New Phytol 177:60-76. 2008
    Plant hormones are considered to be important mediators of the fruit developmental signal after pollination. The role of phytohormones in tomato (Solanum lycopersicum) fruit set was investigated here...
  52. pmc Reconfiguration of the achene and receptacle metabolic networks during strawberry fruit development
    Aaron Fait
    Abteilung Willmitzer, Max Planck Institut fur Molekulare Pflanzenphysiologie, Potsdam Golm, Germany
    Plant Physiol 148:730-50. 2008
    The anatomy of strawberry (Fragaria x ananassa) fruit, in which the achene is found on the outer part of the fruit, makes it an excellent species for studying the regulation of fruit development...
  53. ncbi Effectiveness of school-based interventions in Europe to promote healthy nutrition in children and adolescents: systematic review of published and 'grey' literature
    Eveline Van Cauwenberghe
    Department of Movement and Sport Sciences, Ghent University, 9000 Ghent, Belgium
    Br J Nutr 103:781-97. 2010
    ..In children, strong evidence of effect was found for multicomponent interventions on fruit and vegetable intakes...
  54. pmc Computational annotation of genes differentially expressed along olive fruit development
    Giulio Galla
    Scuola Superiore Sant Anna Pisa, Piazza Martiri della Libertà 33, 56127 Pisa, Italy
    BMC Plant Biol 9:128. 2009
    ..Differently from other fruit tree species, little is known about the physiological and molecular basis of the olive fruit development and a few ..
  55. pmc DkMyb4 is a Myb transcription factor involved in proanthocyanidin biosynthesis in persimmon fruit
    Takashi Akagi
    Laboratory of Pomology, Graduate School of Agriculture, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Plant Physiol 151:2028-45. 2009
    ..PAs) are secondary metabolites that contribute to the protection of the plant and also to the taste of the fruit, mainly through astringency...
  56. ncbi Relationship of fruit and vegetable intake with adiposity: a systematic review
    T A Ledoux
    Department of Pediatrics, USDA ARS Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA
    Obes Rev 12:e143-50. 2011
    b>Fruit and vegetable (FV) intake has been proposed to protect against obesity. The purpose of this paper was to assess the FV consumption to adiposity relationship. Twenty-three publications were included.
  57. ncbi Influences on child fruit and vegetable intake: sociodemographic, parental and child factors in a longitudinal cohort study
    Louise R Jones
    Department of Social Medicine, University of Bristol, Bristol, UK
    Public Health Nutr 13:1122-30. 2010
    To examine the sociodemographic, parental and child factors that predict fruit and vegetable consumption in 7-year-old children.
  58. ncbi Loss of anthocyanins in red-wine grape under high temperature
    Kentaro Mori
    National Research Institute of Brewing, Higashi Hiroshima, Hiroshima 739 0046, Japan
    J Exp Bot 58:1935-45. 2007
    ..These data suggest that the decrease in anthocyanin accumulation under high temperature results from factors such as anthocyanin degradation as well as the inhibition of mRNA transcription of the anthocyanin biosynthetic genes...
  59. pmc The role of ABA in triggering ethylene biosynthesis and ripening of tomato fruit
    Mei Zhang
    College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, PR China
    J Exp Bot 60:1579-88. 2009
    In order to understand more details about the role of abscisic acid (ABA) in fruit ripening and senescence of tomato, two cDNAs (LeNCED1 and LeNCED2) which encode 9-cis-epoxycarotenoid dioxygenase (NCED) as a key enzyme in ABA ..
  60. ncbi Microbiological quality of fresh, minimally-processed fruit and vegetables, and sprouts from retail establishments
    M Abadias
    IRTA, Centre UdL IRTA, XaRTA Postharvest, 191 Rovira Roure, 25198 Lleida, Catalonia, Spain
    Int J Food Microbiol 123:121-9. 2008
    A survey of fresh and minimally-processed fruit and vegetables, and sprouts was conducted in several retail establishments in the Lleida area (Catalonia, Spain) during 2005-2006 to determine whether microbial contamination, and in ..
  61. ncbi Reliability and validity of a questionnaire to measure personal, social and environmental correlates of fruit and vegetable intake in 10-11-year-old children in five European countries
    I De Bourdeaudhuij
    Department of Movement and Sport Sciences, Ghent University, Ghent, Belgium
    Public Health Nutr 8:189-200. 2005
    ..consistency of the scales and the test-retest reliability and predictive validity of behaviour theory-based constructs measuring personal, social and environmental correlates of fruit and vegetable intake in 10-11-year-old children.
  62. ncbi Design and serendipity in establishing a large cohort with wide dietary intake distributions : the National Institutes of Health-American Association of Retired Persons Diet and Health Study
    A Schatzkin
    National Cancer Institute, Bethesda, MD 20892 7232, USA
    Am J Epidemiol 154:1119-25. 2001
    ..The large size and wide intake range of the cohort will provide ample power for examining a number of important diet and cancer hypotheses...
  63. pmc Metabolic profiling during peach fruit development and ripening reveals the metabolic networks that underpin each developmental stage
    Verónica A Lombardo
    Centro de Estudios Fotosintéticos y Bioquímicos, Facultad de Ciencias Bioquimicas y Farmaceuticas, Rosario 2000, Argentina
    Plant Physiol 157:1696-710. 2011
    b>Fruit from rosaceous species collectively display a great variety of flavors and textures as well as a generally high content of nutritionally beneficial metabolites...
  64. ncbi Auxin-induced fruit-set in tomato is mediated in part by gibberellins
    Juan Carlos Serrani
    Instituto de Biología Molecular y Celular de Plantas Universidad Politécnica de Valencia CSIC, Valencia, Spain
    Plant J 56:922-34. 2008
    Tomato (Solanum lycopersicum L.) fruit-set and growth depend on gibberellins (GAs). Auxins, another kind of hormone, can also induce parthenocarpic fruit growth in tomato, although their possible interaction with GAs is unknown...
  65. ncbi FaPYR1 is involved in strawberry fruit ripening
    Ye Mao Chai
    Beijing Key Laboratory of New Technology in Agricultural Application, College of Plant Science and Technology, Beijing University of Agriculture, No 7 Beinong Road, Changping District, Beijing 102206, PR China
    J Exp Bot 62:5079-89. 2011
    Although the plant hormone abscisic acid (ABA) has been suggested to play a role in the ripening of non-climatic fruit, direct genetic/molecular evidence is lacking...
  66. ncbi Study on ionic liquid-based ultrasonic-assisted extraction of biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill
    Chun Hui Ma
    Key Laboratory of Forest Plant Ecology, Northeast Forestry University, 150040 Harbin, PR China
    Anal Chim Acta 689:110-6. 2011
    ..extraction (ILUAE) has been successfully applied in extracting four biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill...
  67. ncbi Genome-wide analysis of auxin response factor (ARF) gene family from tomato and analysis of their role in flower and fruit development
    Rahul Kumar
    Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi 110021, India
    Mol Genet Genomics 285:245-60. 2011
    ..responses during various developmental processes ranging from root and shoot development to flower and fruit development in plants...
  68. ncbi Proteomic analysis of papaya fruit ripening using 2DE-DIGE
    Silvia Beserra Nogueira
    Laboratorio de Quimica, Bioquimica e Biologia Molecular de Alimentos, FCF, Universidade de Sao Paulo, SP, Brazil
    J Proteomics 75:1428-39. 2012
    ..was some correspondence between the identified proteins and the data from previous transcript profiling of papaya fruit, but new, accumulated proteins were identified, which reinforces the importance of differential proteomics as a ..
  69. pmc Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening
    Ana M Fortes
    Plant Systems Biology Lab, Departmento de Biologia Vegetal ICAT, Center for Biodiversity, Functional and Integrative Genomics BioFIG, FCUL, 1749 016 Lisboa, Portugal
    BMC Plant Biol 11:149. 2011
    Grapes (Vitis vinifera L.) are economically the most important fruit crop worldwide...
  70. ncbi A DIGE-based quantitative proteomic analysis of grape berry flesh development and ripening reveals key events in sugar and organic acid metabolism
    Maria José Martínez-Esteso
    Grupo de Proteomica y Genomica Funcional de Plantas, Dept Agroquímica y Bioquímica, Facultad de Ciencias, Universidad de Alicante, Apartado 99, E 03080 Alicante, Spain
    J Exp Bot 62:2521-69. 2011
    Grapevine (Vitis vinifera L.) is an economically important fruit crop. Quality-determining grape components, such as sugars, acids, flavours, anthocyanins, tannins, etc...
  71. ncbi Fruit and vegetable intakes and subsequent changes in body weight in European populations: results from the project on Diet, Obesity, and Genes (DiOGenes)
    Brian Buijsse
    German Institute of Human Nutrition Potsdam Rehbrucke, Department of Epidemiology, Nuthetal, Germany
    Am J Clin Nutr 90:202-9. 2009
    High fruit and vegetable intakes may limit weight gain, particularly in susceptible persons, such as those who stop smoking.
  72. pmc Differential expression of anthocyanin biosynthetic genes in relation to anthocyanin accumulation in the pericarp of Litchi chinensis Sonn
    Yong Zan Wei
    Physiological Laboratory for South China Fruits, College of Horticulture, South China Agricultural University, Guangzhou, China
    PLoS ONE 6:e19455. 2011
    Litchi has diverse fruit color phenotypes, yet no research reflects the biochemical background of this diversity...
  73. pmc Food access and perceptions of the community and household food environment as correlates of fruit and vegetable intake among rural seniors
    Joseph R Sharkey
    Program for Research in Nutrition and Health Disparities, School of Rural Public Health, Texas A and M Health Science Center, MS 1266, College Station, TX 77843 1266, USA
    BMC Geriatr 10:32. 2010
    Although the importance of fruit and vegetable consumption to health has been well established, few studies have focused on access to fruits and vegetables in rural areas; even fewer examined the relationship between food access and ..
  74. ncbi The role of auxin and gibberellin in tomato fruit set
    Maaike de Jong
    Department of Plant Cell Biology, Institute for Water and Wetland Research, Radboud University Nijmegen, Heyendaalseweg, The Netherlands
    J Exp Bot 60:1523-32. 2009
    The initiation of tomato fruit growth, fruit set, is very sensitive to environmental conditions...
  75. ncbi A new proposed guidance system for beverage consumption in the United States
    Barry M Popkin
    Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516 3997, USA
    Am J Clin Nutr 83:529-42. 2006
    ..nonfat) milk and soy beverages, noncalorically sweetened beverages, beverages with some nutritional benefits (fruit and vegetable juices, whole milk, alcohol, and sports drinks), and calorically sweetened, nutrient-poor beverages...
  76. ncbi Antioxidant activity of apple peels
    Kelly Wolfe
    Institute of Comparative and Environmental Toxicology and Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 51:609-14. 2003
    ..The high content of phenolic compounds, antioxidant activity, and antiproliferative activity of apple peels indicate that they may impart health benefits when consumed and should be regarded as a valuable source of antioxidants...
  77. ncbi Antioxidant activity, polyphenol content, and related compounds in different fruit juices and homogenates prepared from 29 different pomegranate accessions
    Revital Tzulker
    Migal Galilee Technology Center, P O Box 831, Kiryat Shmona, 11016, Israel
    J Agric Food Chem 55:9559-70. 2007
    ..of four major hydrolyzable tannins in four different juices/homogenates prepared from different sections of the fruit. To this end, 29 different accessions were tested...
  78. ncbi The potential association between fruit intake and body weight--a review
    S Alinia
    Department of Nutrition, National Food Institute, Technical University of Denmark, Søborg, Denmark
    Obes Rev 10:639-47. 2009
    ..review and analyse published human intervention, prospective observational and cross-sectional studies on fruit intake and body weight in adults...
  79. ncbi Variations in fresh fruit and vegetable quality by store type, urban-rural setting and neighbourhood deprivation in Scotland
    Steven Cummins
    Healthy Environments Research Programme, Department of Geography, Queen Mary, University of London, Mile End Road, London E1 4NS, UK
    Public Health Nutr 12:2044-50. 2009
    Neighbourhood differences in access to fresh fruit and vegetables may explain social inequalities in diet...
  80. ncbi Cultivar and growing region determine the antioxidant polyphenolic concentration and composition of apples grown in New Zealand
    Tony K McGhie
    The Horticulture and Food Research Institute of New Zealand Limited, Private Bag 11030, Palmerston North, New Zealand
    J Agric Food Chem 53:3065-70. 2005
    Evidence suggests that increasing consumption of fruit and vegetables contributes to improved health and well-being by providing protection from diseases including various cancers and cardiovascular disease...
  81. ncbi Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit
    Ammar Saleem
    Department of Chemistry, University of Turku, Kiinamyllynkatu 10, FIN 20014 Turku, Finland
    J Ethnopharmacol 81:327-36. 2002
    A 70% methanol extract of Terminalia chebula fruit, was studied for its effects on growth in several malignant cell lines including a human (MCF-7) and mouse (S115) breast cancer cell line, a human osteosarcoma cell line (HOS-1), a human ..
  82. ncbi Stability in consumption of fruit, vegetables, and sugary foods in a cohort from age 14 to age 21
    N Lien
    Institute for Nutrition Research, University of Oslo, 0316 Oslo, Norway
    Prev Med 33:217-26. 2001
    ..Knowledge about the stability of eating behavior during the transition from adolescence to early adulthood has implication for dietary interventions for children and young adolescents...
  83. ncbi Free school fruit--sustained effect 1 year later
    E Bere
    Department of Nutrition, University of Oslo, Norway
    Health Educ Res 21:268-75. 2006
    This study reports the effect of a school-randomized fruit and vegetable intervention consisting of a subscription to the Norwegian School Fruit Programme at no parental cost, and the Fruit and Vegetables Make the Marks (FVMM) ..
  84. ncbi Fruit, vegetable, and antioxidant intake and all-cause, cancer, and cardiovascular disease mortality in a community-dwelling population in Washington County, Maryland
    Jeanine M Genkinger
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Am J Epidemiol 160:1223-33. 2004
    ..This Washington County, Maryland, prospective study examined the association of fruit, vegetable, and antioxidant intake with all-cause, cancer, and cardiovascular disease death...
  85. ncbi The involvement of auxin in the ripening of climacteric fruits comes of age: the hormone plays a role of its own and has an intense interplay with ethylene in ripening peaches
    Livio Trainotti
    Dipartimento di Biologia, Universita di Padova, Via G Colombo 3, I 35131 Padova, Italy
    J Exp Bot 58:3299-308. 2007
    ..with exogenous ethylene, has shown that other factors also play an important role in the control of climacteric fruit ripening...
  86. ncbi Associations of plant food, dairy product, and meat intakes with 15-y incidence of elevated blood pressure in young black and white adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    Lyn M Steffen
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA
    Am J Clin Nutr 82:1169-77; quiz 1363-4. 2005
    ..Consumption of plant foods and dairy and meat products may moderate increases in blood pressure...
  87. ncbi Functional analysis of the anaphase promoting complex activator CCS52A highlights the crucial role of endo-reduplication for fruit growth in tomato
    Elodie Mathieu-Rivet
    Institut National de la Recherche Agronomique, Universite de Bordeaux, Unité Mixte de Recherche 619 sur la Biologie du Fruit, Institut Fédératif de Recherche 103, Institut National de la Recherche Agronomique, BP 81, F 33883 Villenave d Ornon Cedex, France
    Plant J 62:727-41. 2010
    Tomato fruit growth is characterized by the occurrence of numerous rounds of DNA endo-reduplication in connection with cell expansion and final fruit size determination...
  88. pmc The regulation of MADS-box gene expression during ripening of banana and their regulatory interaction with ethylene
    Tomer Elitzur
    Department of Postharvest Science of Fresh Produce, Agricultural Research Organization ARO, The Volcani Center, PO Box 6, Bet Dagan 50250, Israel
    J Exp Bot 61:1523-35. 2010
    Six MaMADS-box genes have been cloned from the banana fruit cultivar Grand Nain. The similarity of these genes to tomato LeRIN is low and neither MaMADS2 nor MaMADS1 complement the tomato rin mutation...
  89. pmc Enhancement of fruit shelf life by suppressing N-glycan processing enzymes
    Vijaykumar S Meli
    National Institute of Plant Genome Research, New Delhi 110067, India
    Proc Natl Acad Sci U S A 107:2413-8. 2010
    In a globalized economy, the control of fruit ripening is of strategic importance because excessive softening limits shelf life...
  90. pmc Expression profiling of ascorbic acid-related genes during tomato fruit development and ripening and in response to stress conditions
    Eugenia Ioannidi
    Group of Biotechnology of Pharmaceutical Plants, Division of Pharmacognosy Pharmacology, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
    J Exp Bot 60:663-78. 2009
    ..To study the regulation of accumulation of this important nutraceutical in fruit, the expression of 24 tomato (Solanum lycopersicon) genes involved in the biosynthesis, oxidation, and recycling ..
  91. ncbi Food group intake and central obesity among children and adolescents in the Third National Health and Nutrition Examination Survey (NHANES III)
    M Loring Bradlee
    Boston University School of Medicine, Boston, MA 02118, USA
    Public Health Nutr 13:797-805. 2010
    ..To explore mean food group intakes associated with central obesity anthropometry among children and adolescents enrolled in the Third National Health and Nutrition Examination Survey (NHANES III)...
  92. pmc Gene and metabolite regulatory network analysis of early developing fruit tissues highlights new candidate genes for the control of tomato fruit composition and development
    Fabien Mounet
    INRA UMR 619 Biologie du Fruit, Centre de Bordeaux, F 33140 Villenave d Ornon, France
    Plant Physiol 149:1505-28. 2009
    Variations in early fruit development and composition may have major impacts on the taste and the overall quality of ripe tomato (Solanum lycopersicum) fruit...
  93. ncbi Increasing fruit and vegetable intake and decreasing fat and sugar intake in families at risk for childhood obesity
    L H Epstein
    Department of Pediatrics, State University of New York, Buffalo, NY 14214 3000, USA
    Obes Res 9:171-8. 2001
    ....
  94. pmc Proteome changes in the skin of the grape cultivar Barbera among different stages of ripening
    Alfredo S Negri
    Dipartimento di Produzione Vegetale, University of Milan, Via Celoria 2, 20133 Milano, Italy
    BMC Genomics 9:378. 2008
    ....
  95. pmc Prolonged root hypoxia effects on ethylene biosynthesis and perception in tomato fruit
    Faouzi Horchani
    UR d Ecologie Végétale, Departement des Sciences Biologiques, Faculte des Sciences de Tunis, Campus Universitaire, Tunis, Tunisia
    Plant Signal Behav 6:1-4. 2011
    ..on ethylene biosynthesis and perception have been documented in many vegetative organs, but not extensively in fruit. Therefore, in the present study, the effects of root hypoxia on ethylene biosynthesis and perception were ..
  96. ncbi Fruit and vegetable intake and risk of major chronic disease
    Hsin Chia Hung
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 96:1577-84. 2004
    Studies of fruit and vegetable consumption in relation to overall health are limited...
  97. pmc Fruit and vegetables and cancer risk
    T J Key
    Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, Oxford University, Richard Doll Building, Roosevelt Drive, Oxford OX3 7LF, UK
    Br J Cancer 104:6-11. 2011
    The possibility that fruit and vegetables may help to reduce the risk of cancer has been studied for over 30 years, but no protective effects have been firmly established...
  98. pmc Biochemical and molecular analysis of pink tomatoes: deregulated expression of the gene encoding transcription factor SlMYB12 leads to pink tomato fruit color
    Ana Rosa Ballester
    Plant Research International, 6700 AA Wageningen, The Netherlands
    Plant Physiol 152:71-84. 2010
    The color of tomato fruit is mainly determined by carotenoids and flavonoids...
  99. pmc Regulatory features underlying pollination-dependent and -independent tomato fruit set revealed by transcript and primary metabolite profiling
    Hua Wang
    Universite de Toulouse, Institut National Polytechnique Ecole Nationale Superieure Agronomique Toulouse, Génomique et Biotechnologie des Fruits, Castanet Tolosan F 31326, France
    Plant Cell 21:1428-52. 2009
    ..auxin response regulator belonging to the Aux/IAA transcription factor gene family whose downregulation triggers fruit set before pollination, thus giving rise to parthenocarpy...
  100. ncbi Fruit and vegetable intake and risk of cardiovascular disease: the Women's Health Study
    S Liu
    Division of Preventive Medicine and Channing Laboratory, The Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 72:922-8. 2000
    Prospective data relating fruit and vegetable intake to cardiovascular disease (CVD) risk are sparse, particularly for women.
  101. ncbi Anti-atherogenic effects of seabuckthorn (Hippophaea rhamnoides) seed oil
    M Basu
    Defence Institute of Physiology and Allied Sciences, Lucknow Road, Timarpur, Delhi 110054, India
    Phytomedicine 14:770-7. 2007
    ..These observations suggest that supercritical CO(2) extracted SBT seed oil has significant anti-atherogenic and cardioprotective activity...

Research Grants76

  1. Neighborhood Environments and Disparities in Obesity Rates in New York City
    Andrew G Rundle; Fiscal Year: 2010
    ..g. gyms, parks, pleasant walking environments) and healthy diets (e.g. grocery stores, fruit markets, healthy food restaurants) across neighborhoods in New York...
  2. Ceramide Metabolism and Photoreceptor Homeostasis
    Usha R Acharya; Fiscal Year: 2013
    ..The eye of the fruit fly is an excellent model to understand normal pathways in the visual process and to pinpoint mutated genes that ..
  3. Diet Quality and CVD Risk Factors in a Family Based Weight Management Study
    Alice H Lichtenstein; Fiscal Year: 2013
    ..Targeted diet strategies in the core curriculum include increasing highly pigmented fruit and vegetable, and fish intake;substituting non-fat and low-fat for full-fat milk and dairy products;and reducing ..
  4. Oxidative stress and neurogenetic networks in Drosophila
    Robert R H Anholt; Fiscal Year: 2010
    ..The fruit fly, Drosophila melanogaster, provides such a model...
  5. Genetic Control of Axial Patterning in Drosophila Eye
    Amit Singh; Fiscal Year: 2010
    ..The fruit fly, Drosophila, provides an ideal model for genetic analysis of dorsoventral (DV) patterning and growth of the ..
  6. Tunable Insulin Resistance in a Drosophila Model of Diabetes
    ELENA M GRACHEVA; Fiscal Year: 2010
    ..on a proprietary platform optimized for high-throughput drug screening in situ by generating human diseases in the fruit fly Drosophila...
  7. Molecular Genetics of Caloric Restriction in Aging Flies
    Blanka Rogina; Fiscal Year: 2013
    ..Mutation in the Indy gene in the fruit fly, Drosophila melanogaster, dramatically extends life span...
  8. Analyzing Anthrax Toxins in Drosophilia
    Ethan Bier; Fiscal Year: 2013
    ..We discovered this novel effect of anthrax toxins using the model genetic system Drosophila melanogaster (fruit fly) and then validated these effects in human vascular endothelial cells as well as in vivo in mice...
  9. CHONDROPROTECTIVE ACTIVITY OF POMEGRANATE EXTRACT
    Tariq M Haqqi; Fiscal Year: 2010
    ..Pomegranate fruit (Punica granatum L) is revered through the ages for its medicinal properties...
  10. The Regulation of Mitochondrial Function by SIRT3
    Qiang Tong; Fiscal Year: 2010
    ..elegans and fruit flies...
  11. Delivery of Polyphenols in Gum for Treatment of Gingivitis
    Craig S Miller; Fiscal Year: 2013
    ..together will lead to the manufacture and commercial availability of an innovative blackberry chewing gum that releases and delivers natural bioactive substances from freeze-dried fruit powder that will help prevent/treat gingivitis.
  12. Pregnancy and EARly Lifestyle improvement Study (PEARLS)
    Kaumudi J Joshipura; Fiscal Year: 2013
    ..Puerto Rico is a predominantly Hispanic U.S. territory with among the lowest levels of physical activity and fruit, vegetable and whole grain intake, and the highest rates of diabetes, childhood obesity and infant mortality of ..
  13. How do Amine Neurons Work?
    Edward A Kravitz; Fiscal Year: 2013
    ..These experimental approaches are the farthest advanced in fruit flies (Drosophila melanogaster) where powerful genetic methods allow identification and manipulation of single ..
  14. Using Drosophila as a model to understand TDP-43 function in ALS
    David B Morton; Fiscal Year: 2012
    ..We are using the fruit fly, Drosophila melanogaster, as a model to understand the function of TDP- 43 in neurons and the consequences of ..
  15. Evaluating Economic Subsidies To Improve Dietary Intake Among Low Income Families
    Marian L Fitzgibbon; Fiscal Year: 2010
    ..g., whole grain bread) of foods approved for purchase with WIC vouchers and the addition of a monthly fruit and vegetable voucher. These proposed changes will go into effect in August 2009...
  16. MECHANISMS OF CHONDROPROTECTION BY POMEGRANATE FRUIT EXTRACT
    Tariq M Haqqi; Fiscal Year: 2011
    ..Pomegranate fruit (Punica granatum L) is revered through the ages for its medicinal properties...
  17. De novo establishment of Polycomb-group-mediated repression
    Richard S Jones; Fiscal Year: 2010
    ..gene expression, which maintain the silence of numerous developmentally important genes in organisms ranging from fruit flies to humans...
  18. Nutrition Intervention to Reduce Symptoms in Patients with Advanced Heart Failure
    Terry A Lennie; Fiscal Year: 2013
    ..They will take 3 placebo capsules containing soybean oil (500 mg/capsule) and consume their choice of fruit juices that do not contain lycopene daily for six months...
  19. Sugar-sweetened beverage taxes, beverage purchasing patterns, and weight
    Jamie F Chriqui; Fiscal Year: 2013
    ..the relationship between state and local sales taxes on sports drinks, juice drinks containing less than 50% fruit juice, sweetened iced teas, and regular (non-diet) soda and: (1) beverage purchasing patterns for SSBs and non- ..
  20. IL-15 Characterization Through Experimental Immunology
    Michael A Caligiuri; Fiscal Year: 2013
    ..for early phase clinical trials in cancer patients, and work outlined in this proposal will likely bear fruit for such trials...
  21. Flavonoids, esophageal/gastric cardia adenocarcinoma and Barretts Esophagus Risk
    Marilie D Gammon; Fiscal Year: 2013
    ..Epidemiologic studies have shown that diets high in fruit and vegetable consumption are inversely associated with EA/GCA and BE...
  22. Mechanisms of glucosensation mediating food choice behavior in Drosophila
    Monica Dus; Fiscal Year: 2013
    ..Thus, using a genetically amenable model organism such as the fruit fly provides an ideal strategy to complement mammalian research...
  23. Development of a recombinant Nipah virus vaccine for wildlife
    MILOSZ ANDRZEJ FABER; Fiscal Year: 2010
    ..Nipah virus are believed to be caused by contact with pigs infected through the consumption of bat saliva-tainted fruit or bat excrement in pig fodder...
  24. GLUTATHIONE TRANSFERASES IN HUMANS: DIETARY INFLUENCES
    Johanna Lampe; Fiscal Year: 2009
    ..Participants will receive 3 controlled diets in assigned random order: 1) a fruit-and vegetable-free basal diet;2) basal diet + broccoli;and 3) basal diet + green cabbage...
  25. A Drosophila Model for Genetic Studies of Metabolism
    Carl S Thummel; Fiscal Year: 2010
    ..The goal of our research is to use the fruit fly, Drosophila melanogaster, as a simple model system to define the central regulatory pathways that control ..
  26. Proteomics of Cell Death via 2-D Microfluidic Profiling
    DON DEVOE; Fiscal Year: 2009
    ..By using the fruit fly Drosophila melanogaster as a model system, these studies will explore pathways and identify biomarkers ..
  27. Genetic and Molecular Mechanisms of Ethanol-Induced Developmental Defects
    RACHAEL LOUISE FRENCH; Fiscal Year: 2013
    ..Drosophila melanogaster, the common fruit fly, has been utilized extensively in biological research, particularly in genetics and development...
  28. The Ecology, Emergence and Pandemic Potential of Nipah virus in Bangladesh
    Peter Daszak; Fiscal Year: 2012
    Nipah virus (NiV) is a lethal zoonotic paramyxovirus with fruit bat (Pteropus spp.) reservoir hosts. It emerged in 1999 in Malaysia via domestic pig amplifier hosts, causing an encephalitis outbreak with a 40% case fatality rate...
  29. Identifying novel anti-infectives by high through-put screening in whole animals
    Frederick M Ausubel; Fiscal Year: 2013
    ..of nematodes in 384-well plates is followed by secondary screening in a more highly evolved model host, the fruit fly Drosophila melanogaster, increasing the likelihood of isolating drugs that will work in humans...
  30. Identification of Mammalian Genes Promoting Life Extension
    SIU HUNG CHICK; Fiscal Year: 2013
    ..resistance to stress and extended life span has been extensively demonstrated in invertebrates such as yeast, the fruit fly, and C. elegans...
  31. Octopamine Neuroanatomy and Functioning in Fruit Fly Social Behavior
    KYLE LYNN GOBROGGE; Fiscal Year: 2013
    ..The fruit fly (Drosophila melanogaster) genome is fully sequenced, and as a model system, fruit flies offer numerous ..
  32. Steroid-Dependent Changes in the Yorkie Interactome
    Alexey Veraksa; Fiscal Year: 2013
    ..alvador/Warts/Hippo, SWH) pathway is a well-conserved metazoan signaling cascade that restricts organ size in the fruit fly Drosophila melanogaster and limits tumorigenesis in mammals...
  33. Molecular Basis of Noonan Syndrome and Related Disorder
    Bruce D Gelb; Fiscal Year: 2013
    ..therapies for RAF1- related HCM can be identified through screening FDA-approved drugs using a transgenic fruit fly model and that candidate RASopathy therapies identified in fruit flies will prove effective in preventing ..
  34. Redefining Human Myocardial Biology
    Annarosa Leri; Fiscal Year: 2013
    ..Findings in nematodes, fruit flies, zebra fish and rodents have often been translated to human beings with little caution, emphasizing the ..
  35. Drosophila feeding behavior: New tools for the genetic dissection of prandiology
    William W Ja; Fiscal Year: 2012
    ..The fruit fly, Drosophila melanogaster, is a powerful system for studying the relationship of genes with behavior and ..
  36. Hormonal Modulation of Aggression in Drosophila
    Edward A Kravitz; Fiscal Year: 2013
    ..Amines have been shown to be important in aggression in all species of animals examined thus far. Fruit flies are no exception...
  37. Interplay between the Endocrine and Innate Systems of Drosphila
    Neal Silverman; Fiscal Year: 2013
    ..This proposal uses the fruit fly Drosophila melanogaster as a model for the study of these interactions...
  38. Developing cell lines from clock neurons in Drosophila
    Paul E Hardin; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The identification and analysis of clock genes in the fruit fly, Drosophila melanogaster, revealed that the circadian clock is based on autoregulatory feedback loops in gene expression...
  39. Fruit exosome-like particles for therapeutic delivery of extracellular miRNAs
    Huang Ge Zhang; Fiscal Year: 2013
    ..We will accomplish this in our study by knock-out and knock-in strategies. ..
  40. Risk Factors for Urinary Incontinence in Women
    Francine Grodstein; Fiscal Year: 2010
    ..older women;women with incontinence are often given advice to reduce certain foods, such as caffeine, and acidic fruit/vegetables...
  41. Inhibition in the progression of preinvasive lung cancer by pomegranate.
    Naghma Khan; Fiscal Year: 2012
    ..matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis, pomegranate fruit extract (PFE) was found to contain anthocyanins (such as delphinidin, cyanidin and pelargonidin) and several ..
  42. Mitochondrial Dysfunction in Neurodegeneration of Aging
    Gary E Gibson; Fiscal Year: 2013
    ..will be tested at multiple levels of biological complexity: isolated proteins, gene transcription, cultured cells, fruit flies and transgenic mice...
  43. Translational regulation of cellular morphogenesis in early Drosophila embryos
    Paul M Macdonald; Fiscal Year: 2012
    ..We have found that the Drosophila (fruit fly) counterpart of this protein is required for an early stage of embryonic development that is evolutionarily ..
  44. Mothers in Motion Program to Prevent Weight Gain in Overweight/Obese WIC Mothers
    Mei Wei Chang; Fiscal Year: 2013
    ..Mediating factors will include improvements in dietary fat, fruit, and vegetable intake;physical activity;stress;feelings;and personal (self-efficacy and emotional coping response) ..
  45. Retinal Cell-Fate Determination and Pattern Formation
    Graeme Mardon; Fiscal Year: 2012
    ..Both genes are highly conserved from fruit flies to humans and are known to play essential roles in human development, including the eye...
  46. Function of the Six and Eya Genes in Retinal Development
    Justin P Kumar; Fiscal Year: 2012
    ..retinal defects in human patients and mouse model systems as well as total elimination of the compound eyes of the fruit fly, Drosophila melanogaster...
  47. Role of ERK1/2 in Neuromuscular Synapses and Myofiber Development in vivo
    Mendell Rimer; Fiscal Year: 2013
    ..A strategy of conditional gene targeting that has recently bear fruit in other cells of the peripheral nervous system will be used to selectively inactivate Erk1/2 in skeletal muscle ..
  48. Taste and feeding circuits in Drosophila
    MICHAEL DOUGLAS GORDON; Fiscal Year: 2010
    ..Experiments in this proposal will examine the neural substrates of taste perception and feeding behavior in the fruit fly Drosophila melanogaster...
  49. Ecdysone modulation of sexual behavior in Drosophila melanogaster
    GEOFFREY GANTER; Fiscal Year: 2009
    We will explore the control of sexual behavior of the fruit fly by the steroid hormone ecdysone...
  50. Benzophenones: Novel natural agents which inhibits HIV and Candida
    Ramiro Mendonca Murata; Fiscal Year: 2013
    ..Phytochemical investigations of the Rheedia brasiliensis'fruit resulted in the isolation and identification of new potentially bioactive benzophenones...
  51. Epigenetic regulation of metabolism in Drosophila
    Carl S Thummel; Fiscal Year: 2013
    ..We have discovered that the fruit fly Drosophila shares the ability to link the metabolic status of parents with that of their offspring, that ..
  52. Benzophenones: Novel natural agents which inhibits HIV and Candida
    Ramiro Mendonca Murata; Fiscal Year: 2011
    ..Phytochemical investigations of the Rheedia brasiliensis'fruit resulted in the isolation and identification of new potentially bioactive benzophenones...
  53. Native Healthy Lifestyle: A Return to Balance
    ELISA TAN LEE; Fiscal Year: 2010
    ..The primary outcome measures will be behavioral modification outcomes, including caloric intake, sodium intake and fruit and vegetable consumption for diet and pedometer measurements for physical activity...
  54. Neuronal Cell Cycle and Survival
    Nicholas E Baker; Fiscal Year: 2013
    ..The eye of the fruit fly Drosophila melanogaster will be used to evaluate this new hypothesis, and to identify specific aspects of cell ..
  55. Molecular Mechanisms of Lifespan Extension by Dietary Restriction in Drosophila
    Pankaj Kapahi; Fiscal Year: 2013
    ..restriction (DR) provides the most robust method of lifespan extension in species as diverse as yeast, worms, fruit flies and rodents...
  56. A Drosophila Model for Williams Syndrome Cognitive Processing
    Ralph J Greenspan; Fiscal Year: 2010
    ..We will then use the tools of Drosophila genetics to identify the key interacting genes. The fruit fly has emerged in recent years not only as a powerful experimental system for understanding how genes influence ..
  57. Mechanisms of receptor protein tyrosine phosphatase signaling in Drosophila devel
    Jessica E Treisman; Fiscal Year: 2013
    ..The fruit fly Drosophila offers an attractive model system in which to address the mechanisms of RPTP function in vivo...
  58. Function of the Six and Eya Genes in Retinal Development
    JUSTIN KUMAR; Fiscal Year: 2009
    ..retinal defects in human patients and mouse model systems as well as total elimination of the compound eyes of the fruit fly, Drosophila melanogaster...
  59. Bacterial fermentation in skin microbiome as probiotics (Bfismp) against S. aureu
    Chun Ming Huang; Fiscal Year: 2013
    ..Like microbial competition via fermentation in a ripening fruit, bacterial interference via fermentation has been found in the deep-seated skin abscesses where is an anaerobic ..
  60. Runt-dependent regulation of enhancer-promoter interactions
    JOHN PETER GERGEN; Fiscal Year: 2013
    ..upstream, downstream, or even within the transcribed region of a gene, and in animal systems extending from fruit fly to man are frequently many kilobases removed from the transcription start site...
  61. Integration and Excision by Serine Intergrases
    Graham F Hatfull; Fiscal Year: 2013
    ..for adaptation to work in heterologous genetic systems including in other bacterial pathogens, malaria, in worms, fruit flies, mammalian cell culture, and in mice...
  62. Manipulation of stem cell activity and cell death by intracellular bacteria
    Horacio M Frydman; Fiscal Year: 2013
    ..b>Fruit fly Wolbachia strains can invade and sustain themselves in mosquito populations, reduce adult lifespan, affect ..
  63. A New Point of Use Decontamination Method for Fresh Produce
    ADRIAN J DENVIR; Fiscal Year: 2010
    ..As fruit and vegetable consumption continues to increase, fresh produce has become the second most common medium for ..
  64. Establishing Drosophila as a Model to Study Hutchinson-Gilford Progeria Syndrome
    Sandra Schulze; Fiscal Year: 2009
    ..The experiments described in this proposal will establish the fruit fly Drosophila as a model to study human Lamin A processing...
  65. Nutrition Program-Caribbean Hispanic elders & diabetes
    ODILIA BERMUDEZ; Fiscal Year: 2003
    ..care of Hispanics with diabetes, an ethnically and culturally specific nutrition program will result in improved fruit and vegetable and fiber intakes...
  66. Are anthocyanins necessary for oral cancer chemoprevention by berries?
    CHRISTOPHER WEGHORST; Fiscal Year: 2009
    ..A pressing, yet unanswered, question remains "What types of polyphenols in fruit are primarily responsible for these activities?" Prior studies have employed lyophilized powders or extracts of ..
  67. Novel Simulated Moving Bed Chromatography Device to Purify Recombinant Proteins
    ROBERT MIERENDORF; Fiscal Year: 2007
    ..methods for structural determination of recombinant proteins, focusing on the so-called "low-hanging fruit", i.e. proteins which are expressed at high levels as soluble, correctly folded species in E...
  68. Defining the Mammalian Intercellular Bridge Interactome
    Martin M Matzuk; Fiscal Year: 2010
    ..Although several fruit fly intercellular bridge (ring canal) proteins have been uncovered, until our knockout of testis expressed gene 14 ..
  69. Genetic and Biochemical Analyses of Germline Development in Drosophila
    Alexey Arkov; Fiscal Year: 2009
    ..genes show striking similarity to human genes and many developmental processes follow the same rules in both fruit flies and humans...
  70. A web-based tailored health behavior intervention for African American colon canc
    Marlyn Allicock; Fiscal Year: 2010
    ..Results showed significant improvements (p<.05) for fruit and vegetable consumption (0.6 servings) and recreational physical activity (2.5 MET hours per week)...
  71. Cancer Chemoprevention by Pomegranate Fruit Extract
    Farrukh Afaq; Fiscal Year: 2006
    ..Pomegranate fruit extract (PFE), derived from the tree of Punica granatum, is a rich source of two types of polyphenolic compounds; ..
  72. Clade-specific changes in transcription of olfactory genes in fruit flies
    EREZYILMAZ DENIZ; Fiscal Year: 2009
    ..sechellia. While D. melanogaster and D. simulans are generalists, D. sechellia only lays eggs on the morinda fruit. A key component of this ecological specialization involves evolution of the olfactory system...
  73. Analysis of Phenolic Phytochemical by ESI-MS
    Jennifer Brodbelt; Fiscal Year: 2003
    ..of phenolic phytochemicals and their metabolites in urine, tissue and food, especially soybeans, kale and citrus fruit. Many phenolic compounds are plant pigments that are known to yield health benefits as dietary phytochemicals, ..
  74. Translating a nutrition intervention thru WIC & Minority Health Promotion Centers
    Kim Gans; Fiscal Year: 2009
    ..the process of disseminating a tailored nutrition intervention that has been shown to be efficacious in improving fruit and vegetable (FV) intake in diverse low income audiences as part of a NCI-funded efficacy study entitled Your ..
  75. NEUROBIOLOGY OF DROSOPHILA CONFERENCE
    David Stewart; Fiscal Year: 2007
    ..the latest advances in neurobiology research that are being made in the highly successful model system of the fruit fly Drosophila melanogaster...
  76. 2009 Neurobiology of Drosophila Conference
    David Stewart; Fiscal Year: 2009
    ..the latest advances in the neurobiology research that are being made in the highly successful model system the fruit fly Drosophila melanogaster...