dietary fiber

Summary

Summary: The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins.

Top Publications

  1. ncbi Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study
    Sheila A Bingham
    MRC Dunn Human Nutrition Unit, Cambridge, UK
    Lancet 361:1496-501. 2003
  2. ncbi Effect of a low-glycemic index or a high-cereal fiber diet on type 2 diabetes: a randomized trial
    David J A Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
    JAMA 300:2742-53. 2008
  3. ncbi Dietary fiber and colorectal cancer risk: a nested case-control study using food diaries
    Christina C Dahm
    Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK
    J Natl Cancer Inst 102:614-26. 2010
  4. ncbi Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides
    D L Topping
    Commonwealth Scientific and Industrial Research Organization, Health Sciences and Nutrition, Adelaide, Australia
    Physiol Rev 81:1031-64. 2001
  5. ncbi Colonic health: fermentation and short chain fatty acids
    Julia M W Wong
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ont, Canada
    J Clin Gastroenterol 40:235-43. 2006
  6. ncbi Health benefits of dietary fiber
    James W Anderson
    Department of Internal Medicine and Nutritional Sciences Program, University of Kentucky, Lexington, Kentucky 40502, USA
    Nutr Rev 67:188-205. 2009
  7. pmc Whole grain, bran, and germ intake and risk of type 2 diabetes: a prospective cohort study and systematic review
    Jeroen S L de Munter
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 4:e261. 2007
  8. ncbi Review article: the role of butyrate on colonic function
    H M Hamer
    TI Food and Nutrition, Wageningen, The Netherlands
    Aliment Pharmacol Ther 27:104-19. 2008
  9. ncbi New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
    Anthony Fardet
    INRA, UMR 1019 Nutrition Humaine, F 63122 Saint Genes Champanelle, France
    Nutr Res Rev 23:65-134. 2010
  10. ncbi Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis
    Matthias B Schulze
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Arch Intern Med 167:956-65. 2007

Detail Information

Publications371 found, 100 shown here

  1. ncbi Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study
    Sheila A Bingham
    MRC Dunn Human Nutrition Unit, Cambridge, UK
    Lancet 361:1496-501. 2003
    ..Dietary fibre is thought to protect against colorectal cancer but this view has been challenged by recent prospective and intervention studies that showed no protective effect...
  2. ncbi Effect of a low-glycemic index or a high-cereal fiber diet on type 2 diabetes: a randomized trial
    David J A Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
    JAMA 300:2742-53. 2008
    ..Low-glycemic index diets may improve both glycemic control and cardiovascular risk factors for patients with type 2 diabetes but debate over their effectiveness continues due to trial limitations...
  3. ncbi Dietary fiber and colorectal cancer risk: a nested case-control study using food diaries
    Christina C Dahm
    Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK
    J Natl Cancer Inst 102:614-26. 2010
    Results of epidemiological studies of dietary fiber and colorectal cancer risk have not been consistent, possibly because of attenuation of associations due to measurement error in dietary exposure ascertainment.
  4. ncbi Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides
    D L Topping
    Commonwealth Scientific and Industrial Research Organization, Health Sciences and Nutrition, Adelaide, Australia
    Physiol Rev 81:1031-64. 2001
    ..Human colonic bacteria ferment RS and nonstarch polysaccharides (NSP; major components of dietary fiber) to short-chain fatty acids (SCFA), mainly acetate, propionate, and butyrate...
  5. ncbi Colonic health: fermentation and short chain fatty acids
    Julia M W Wong
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ont, Canada
    J Clin Gastroenterol 40:235-43. 2006
    ..Dietary carbohydrates, specifically resistant starches and dietary fiber, are substrates for fermentation that produce SCFAs, primarily acetate, propionate, and butyrate, as end ..
  6. ncbi Health benefits of dietary fiber
    James W Anderson
    Department of Internal Medicine and Nutritional Sciences Program, University of Kentucky, Lexington, Kentucky 40502, USA
    Nutr Rev 67:188-205. 2009
    b>Dietary fiber intake provides many health benefits. However, average fiber intakes for US children and adults are less than half of the recommended levels...
  7. pmc Whole grain, bran, and germ intake and risk of type 2 diabetes: a prospective cohort study and systematic review
    Jeroen S L de Munter
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 4:e261. 2007
    ..We evaluated intakes of whole grain, bran, and germ in relation to risk of type 2 diabetes in prospective cohort studies...
  8. ncbi Review article: the role of butyrate on colonic function
    H M Hamer
    TI Food and Nutrition, Wageningen, The Netherlands
    Aliment Pharmacol Ther 27:104-19. 2008
    ..Butyrate is an important energy source for intestinal epithelial cells and plays a role in the maintenance of colonic homeostasis...
  9. ncbi New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
    Anthony Fardet
    INRA, UMR 1019 Nutrition Humaine, F 63122 Saint Genes Champanelle, France
    Nutr Res Rev 23:65-134. 2010
    ..Finally, benefits of nutrigenomics to study complex physiological effects of the 'whole-grain package', and the most promising ways for improving the nutritional quality of cereal products are discussed...
  10. ncbi Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis
    Matthias B Schulze
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Arch Intern Med 167:956-65. 2007
    ..We examined associations between fiber and magnesium intake and risk of type 2 diabetes and summarized existing prospective studies by meta-analysis...
  11. ncbi Dietary fiber and breast cancer risk: a systematic review and meta-analysis of prospective studies
    D Aune
    Department of Epidemiology and Biostatistics, Imperial College, London, UK
    Ann Oncol 23:1394-402. 2012
    Evidence from case-control studies suggest that dietary fiber may be inversely related to breast cancer risk, but it is unclear if this is supported by prospective data...
  12. pmc The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer
    Melissa M Kaczmarczyk
    Division of Nutritional Sciences, College of Medicine, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Metabolism 61:1058-66. 2012
    b>Dietary fiber (DF) is deemed to be a key component in healthy eating...
  13. pmc Effects of dietary fiber and its components on metabolic health
    James M Lattimer
    Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA
    Nutrients 2:1266-89. 2010
    b>Dietary fiber and whole grains contain a unique blend of bioactive components including resistant starches, vitamins, minerals, phytochemicals and antioxidants...
  14. ncbi Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal
    Patrice D Cani
    Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Universite Catholique de Louvain, Brussels, Belgium
    Am J Clin Nutr 90:1236-43. 2009
    ..In rodents, these effects are associated with an increase in plasma gut peptide concentrations, which are involved in appetite regulation and glucose homeostasis...
  15. ncbi Resistant starch improves insulin sensitivity in metabolic syndrome
    K L Johnston
    Diabetes and Endocrinology, Postgraduate Medical School, University of Surrey, Guildford, UK
    Diabet Med 27:391-7. 2010
    ..This study was undertaken to assess whether chronic consumption of this type of fibre in individuals with the metabolic syndrome would improve insulin sensitivity via changes in ectopic fat storage...
  16. pmc Dietary fiber and saturated fat intake associations with cardiovascular disease differ by sex in the Malmö Diet and Cancer Cohort: a prospective study
    Peter Wallström
    Nutrition Epidemiology Research Group, Department of Clinical Sciences, Lund University, Malmo, Sweden
    PLoS ONE 7:e31637. 2012
    The aim of the study was to examine associations between intake of macronutrients and dietary fiber and incident ischemic cardiovascular disease (iCVD) in men and women.
  17. ncbi Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women
    Simin Liu
    Division of Preventive Medicine and the Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 78:920-7. 2003
    Although increased consumption of dietary fiber and grain products is widely recommended to maintain healthy body weight, little is known about the relation of whole grains to body weight and long-term weight changes.
  18. pmc Dietary fibre intake and risks of cancers of the colon and rectum in the European prospective investigation into cancer and nutrition (EPIC)
    Neil Murphy
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    PLoS ONE 7:e39361. 2012
    ..We explored whether the association remained after longer follow-up with a near threefold increase in colorectal cancer cases, and if the association varied by gender and tumour location...
  19. ncbi Dietary fiber for the treatment of type 2 diabetes mellitus: a meta-analysis
    Robert E Post
    Department of Family Medicine, Medical University of South Carolina, Charleston, USA
    J Am Board Fam Med 25:16-23. 2012
    ..The purpose of this study was to determine if an increase in dietary fiber affects glycosylated hemoglobin (HbA1c) and fasting blood glucose in patients with type 2 diabetes mellitus.
  20. ncbi Effects of dietary fiber on the feline gastrointestinal metagenome
    Kathleen A Barry
    Department of Animal Sciences, University of Illinois, Urbana, Illinois 61801, United States
    J Proteome Res 11:5924-33. 2012
    ..While the cat is an obligate carnivore, its gut microbiome is similar regarding microbial phylogeny and gene content to omnivores...
  21. ncbi Position of the American Dietetic Association: health implications of dietary fiber
    Joanne L Slavin
    American Dietetic Association, USA
    J Am Diet Assoc 108:1716-31. 2008
    It is the position of the American Dietetic Association that the public should consume adequate amounts of dietary fiber from a variety of plant foods. Populations that consume more dietary fiber have less chronic disease...
  22. ncbi Adaptation of colonic fermentation and glucagon-like peptide-1 secretion with increased wheat fibre intake for 1 year in hyperinsulinaemic human subjects
    Kristin R Freeland
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    Br J Nutr 103:82-90. 2010
    ..Since GLP-1 may increase insulin sensitivity and secretion, these results may provide a mechanism for the epidemiological association between high cereal fibre intake and reduced risk for diabetes...
  23. pmc Putting the whole grain puzzle together: health benefits associated with whole grains--summary of American Society for Nutrition 2010 Satellite Symposium
    Satya S Jonnalagadda
    General Mills Bell Institute of Health and Nutrition, Golden Valley, MN 55427, USA
    J Nutr 141:1011S-22S. 2011
    ..The symposium also highlighted the need for further research to examine the role of whole grain foods in disease prevention and management to gain a better understanding of their mechanisms of action...
  24. ncbi Evidence-based nutritional approaches to the treatment and prevention of diabetes mellitus
    J I Mann
    Edgar National Centre for Diabetes Research, Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Nutr Metab Cardiovasc Dis 14:373-94. 2004
  25. ncbi Dietary fiber and weight regulation
    N C Howarth
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Nutr Rev 59:129-39. 2001
    The influence of dietary fiber on energy regulation remains controversial. This review summarizes published studies on the effects of dietary fiber on hunger, satiety, energy intake, and body composition in healthy individuals...
  26. ncbi Dietary fiber and body weight
    Joanne L Slavin
    Department of Food Science and Nutrition, University of Minnesota, St Paul, Minnesota, USA
    Nutrition 21:411-8. 2005
    This review provides an update of recent studies of dietary fiber and weight and includes a discussion of potential mechanisms of how dietary fiber can aid weight loss and weight maintenance.
  27. ncbi Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies
    Mark A Pereira
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN55454, USA
    Arch Intern Med 164:370-6. 2004
    Few epidemiologic studies of dietary fiber intake and risk of coronary heart disease have compared fiber types (cereal, fruit, and vegetable) or included sex-specific results...
  28. pmc Functional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes
    Lena Tasse
    Universite de Toulouse, INSA, UPS, INP, LISBP, F 31077 Toulouse, France
    Genome Res 20:1605-12. 2010
    ..the in-depth pyrosequencing of specific regions of the human gut metagenome encoding the CAZymes involved in dietary fiber breakdown. High-throughput functional screens were first applied to a library covering 5...
  29. ncbi The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome
    Heather I Katcher
    The Huck Institutes of the Life Sciences, Department of Nutritional Sciences, Core Endocrine Laboratory, Pennsylvania State University, University Park 16802, USA
    Am J Clin Nutr 87:79-90. 2008
    ..However, few clinical trials have tested whether incorporating whole grains into a hypocaloric diet increases weight loss and improves CVD risk factors...
  30. ncbi Dietary intake of whole and refined grain breakfast cereals and weight gain in men
    Lydia A Bazzano
    Department of Medicine, Beth Israel Deaconess Hospital, Boston, Massachusetts, USA
    Obes Res 13:1952-60. 2005
    ..The aim of this study was to prospectively assess the association between whole and refined grain breakfast cereal intakes and risk of overweight (BMI >or= 25 kg/m(2)) and weight gain...
  31. ncbi Glycemic index, glycemic load, and cereal fiber intake and risk of type 2 diabetes in US black women
    Supriya Krishnan
    Slone Epidemiology Center, Boston, MA 02215, USA
    Arch Intern Med 167:2304-9. 2007
    ..Previous studies of carbohydrate quality and risk of type 2 diabetes mellitus have yielded inconsistent findings. Because diet is in part culturally determined, a study of dietary factors in US black women is of interest...
  32. pmc Whole-grain, cereal fiber, bran, and germ intake and the risks of all-cause and cardiovascular disease-specific mortality among women with type 2 diabetes mellitus
    Meian He
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 121:2162-8. 2010
    ..This study investigated whole grain and its components cereal fiber, bran, and germ in relation to all-cause and CVD-specific mortality in patients with type 2 diabetes mellitus...
  33. ncbi Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose
    Kaisa Raninen
    Food and Health Research Centre, Department of Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Nutr Rev 69:9-21. 2011
    b>Dietary fiber is a nutritional concept based not on physiological functions but on defined chemical and physical properties...
  34. pmc Dietary fiber, carbohydrate quality and quantity, and mortality risk of individuals with diabetes mellitus
    Koert N J Burger
    University Medical Center, Utrecht, The Netherlands
    PLoS ONE 7:e43127. 2012
    b>Dietary fiber, carbohydrate quality and quantity are associated with mortality risk in the general population. Whether this is also the case among diabetes patients is unknown.
  35. ncbi Fiber intake and total and cause-specific mortality in the European Prospective Investigation into Cancer and Nutrition cohort
    Shu Chun Chuang
    School of Public Health, Imperial College London, London, United Kingdom
    Am J Clin Nutr 96:164-74. 2012
    Previous studies have shown that high fiber intake is associated with lower mortality. However, little is known about the association of dietary fiber with specific causes of death other than cardiovascular disease (CVD).
  36. ncbi Whole-grain ready-to-eat oat cereal, as part of a dietary program for weight loss, reduces low-density lipoprotein cholesterol in adults with overweight and obesity more than a dietary program including low-fiber control foods
    Kevin C Maki
    Provident Clinical Research, Glen Ellyn, IL 60137, USA
    J Am Diet Assoc 110:205-14. 2010
    ....
  37. ncbi Trends in dietary fiber intake in the United States, 1999-2008
    Dana E King
    Department of Family Medicine, Medical University of South Carolina, 295 Calhoun St, Charleston, SC 29425, USA
    J Acad Nutr Diet 112:642-8. 2012
    Intake of dietary fiber has been recommended for many years as part of the guidelines from the American Heart Association, the Institute of Medicine, and other groups...
  38. ncbi Plausible mechanisms for the protectiveness of whole grains
    J L Slavin
    Department of Food Science and Nutrition, University of Minnesota, St Paul, MN 55108, USA
    Am J Clin Nutr 70:459S-463S. 1999
    ..Components in whole grains that may be protective include compounds that affect the gut environment, such as dietary fiber, resistant starch, and oligosaccharides...
  39. pmc Intake of whole grains, refined grains, and cereal fiber measured with 7-d diet records and associations with risk factors for chronic disease
    P K Newby
    Department of Pediatrics, Boston University School of Medicine, Boston Medical Center, Boston, MA 02118, USA
    Am J Clin Nutr 86:1745-53. 2007
    ..Single-nutrient studies are also needed to explore the mechanisms by which foods may be protective...
  40. ncbi The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects
    Joshua Tarini
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON M5S 3E2, Canada
    Appl Physiol Nutr Metab 35:9-16. 2010
    ....
  41. pmc Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial
    Katie M Queenan
    Department of Food Science and Nutrition, University of Minnesota, St Paul, MN, USA
    Nutr J 6:6. 2007
    ..We also compared the fermentability of concentrated oat beta-glucan with inulin and guar gum in a model intestinal fermentation system...
  42. pmc Dietary fiber, magnesium, and glycemic load alter risk of type 2 diabetes in a multiethnic cohort in Hawaii
    Beth N Hopping
    Department of Epidemiology, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    J Nutr 140:68-74. 2010
    The influence of dietary fiber, magnesium (Mg), and glycemic load (GL) on diabetes was examined in the Hawaii component of the Multiethnic Cohort...
  43. ncbi EPIC-Oxford: lifestyle characteristics and nutrient intakes in a cohort of 33 883 meat-eaters and 31 546 non meat-eaters in the UK
    Gwyneth K Davey
    Cancer Research UK Epidemiology Unit, University of Oxford, Gibson Building, Radcliffe Infirmary, Oxford OX2 6HE, UK
    Public Health Nutr 6:259-69. 2003
    ..To describe the lifestyle characteristics and nutrient intakes of the Oxford cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  44. ncbi A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women
    S Liu
    Departments of Epidemiology and Nutrition, The Harvard School of Public Health, Boston, MA 02215, USA
    Am J Clin Nutr 71:1455-61. 2000
    ..Little is known about the effects of the amount and type of carbohydrates on risk of coronary heart disease (CHD)...
  45. ncbi Cereal fiber improves whole-body insulin sensitivity in overweight and obese women
    Martin O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal 14558, Germany
    Diabetes Care 29:775-80. 2006
    ..The pathogenic background of this phenomenon is unknown. Based on recent findings, we hypothesized that intake of purified insoluble oat fiber may improve whole-body insulin sensitivity...
  46. ncbi Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study
    Angela D Liese
    Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, 29208, USA
    Am J Clin Nutr 78:965-71. 2003
    ..Increased intake of whole-grain foods has been related to a reduced risk of developing diabetes and heart disease. One underlying pathway for this relation may be increased insulin sensitivity...
  47. ncbi Glycemic index and dietary fiber and the risk of type 2 diabetes
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Diabetes Care 27:2701-6. 2004
    ..To examine associations between type 2 diabetes and fiber, glycemic load (GL), dietary glycemic index (GI), and fiber-rich foods...
  48. ncbi Dietary fiber intake is associated with reduced risk of mortality from cardiovascular disease among Japanese men and women
    Ehab S Eshak
    Public Health, Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Suita Shi, Osaka, Japan
    J Nutr 140:1445-53. 2010
    b>Dietary fiber protects against coronary heart disease (CHD), but evidence in Asia is limited...
  49. ncbi Effects of dietary fibre on subjective appetite, energy intake and body weight: a systematic review of randomized controlled trials
    A J Wanders
    Division of Human Nutrition, Wageningen University, The Netherlands
    Obes Rev 12:724-39. 2011
    ..Short- and long-term effects of dietary fibres appear to differ and multiple mechanisms relating to their different physicochemical properties seem to interplay. This warrants further exploration...
  50. ncbi Dietary fiber and subsequent changes in body weight and waist circumference in European men and women
    Huaidong Du
    National Institute for Public Health and the Environment RIVM, Bilthoven, Netherlands
    Am J Clin Nutr 91:329-36. 2010
    b>Dietary fiber may play a role in obesity prevention. Until now, the role that fiber from different sources plays in weight change had rarely been studied.
  51. pmc Dietary fiber supplements: effects in obesity and metabolic syndrome and relationship to gastrointestinal functions
    Athanasios Papathanasopoulos
    Clinical Enteric Neuroscience Translational and Epidemiological Research, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Gastroenterology 138:65-72.e1-2. 2010
    b>Dietary fiber is a term that reflects a heterogeneous group of natural food sources, processed grains, and commercial supplements...
  52. ncbi Cholesterol-lowering effect of beta-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when beta-glucan is incorporated into bread and cookies
    Daniëlle A J M Kerckhoffs
    Department of Human Biology, Maastricht University, Maastricht, The Netherlands
    Am J Clin Nutr 78:221-7. 2003
    ..Findings about the effects of beta-glucan on serum lipoproteins are conflicting...
  53. ncbi Why whole grains are protective: biological mechanisms
    Joanne Slavin
    Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, St Paul, MN 55108, USA
    Proc Nutr Soc 62:129-34. 2003
    ..The few whole-grain feeding studies that are available show improvements in biomarkers with whole-grain consumption, such as weight loss, blood lipid improvement and antioxidant protection...
  54. ncbi A diet rich in dietary fiber from cocoa improves lipid profile and reduces malondialdehyde in hypercholesterolemic rats
    Elena Lecumberri
    Department of Metabolism and Nutrition, Instituto del Frio CSIC, Madrid, Spain
    Nutrition 23:332-41. 2007
    The potential hypolipidemic effect of a new cocoa product rich in dietary fiber (DF) naturally containing antioxidant polyphenols (cocoa fiber [CF]) was studied in a rat model of dietary-induced hypercholesterolemia.
  55. pmc Dietary fiber intake and mortality in the NIH-AARP diet and health study
    Yikyung Park
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA
    Arch Intern Med 171:1061-8. 2011
    b>Dietary fiber has been hypothesized to lower the risk of coronary heart disease, diabetes, and some cancers. However, little is known of the effect of dietary fiber intake on total death and cause-specific deaths.
  56. ncbi Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat
    Michael J Keenan
    Human Nutrition and Food Division, School of Human Ecology, Louisiana State University Agriculture Center, Baton Rouge, LA 70803, USA
    Obesity (Silver Spring) 14:1523-34. 2006
    ....
  57. ncbi Whole-grain and fiber intake and the incidence of type 2 diabetes
    Jukka Montonen
    National Public Health Institute, Helsinki, Finland
    Am J Clin Nutr 77:622-9. 2003
    ..Epidemiologic evidence of a preventive effect of whole grain against type 2 diabetes is mainly based on data from women. Information specific to men and women is needed...
  58. ncbi Carbohydrate intake, glycemic index, glycemic load, and dietary fiber in relation to risk of stroke in women
    Kyungwon Oh
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:161-9. 2005
    ..In addition, high consumption of cereal fiber was associated with lower risk of total and hemorrhagic stroke...
  59. ncbi Intake of refined carbohydrates and whole grain foods in relation to risk of type 2 diabetes mellitus and coronary heart disease
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard School of Medicine, Boston, Massachusetts 02115, USA
    J Am Coll Nutr 21:298-306. 2002
    ..It seems prudent, therefore, to distinguish whole-grain rather than refined-grain cereal products for the prevention of chronic diseases...
  60. ncbi Dietary fiber and blood pressure: a meta-analysis of randomized placebo-controlled trials
    Martinette T Streppel
    Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Arch Intern Med 165:150-6. 2005
    b>Dietary fiber is part of a healthy diet and may exert a protective effect in the cardiovascular system. The effect of fiber intake on blood pressure (BP) has not yet been established.
  61. ncbi Relationship between number of metabolic syndrome components and dietary factors in middle-aged and elderly Japanese subjects
    Rei Otsuka
    Department of Epidemiology, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Aichi, Japan
    Hypertens Res 33:548-54. 2010
    ..for age, energy intake, alcohol intake, smoking status and physical activity, a lower intake of vitamin B6 and dietary fiber in men, and lower intake of calcium, milk and dairy products and higher intake of cereal in women were related ..
  62. ncbi Absorption of hydroxycinnamates in humans after high-bran cereal consumption
    Sandra M Kern
    Institute of Food Research, Nutrition Division, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    J Agric Food Chem 51:6050-5. 2003
    ..The data show that ferulic and sinapic acids are taken up in humans from dietary high bran wheat but that absorption is limited and may originate only from the free and soluble portions present in the cereal...
  63. ncbi Dietary fiber intake and risk of breast cancer: a meta-analysis of prospective cohort studies
    Jia Yi Dong
    Department of Nutrition and Food Hygiene, School of Radiation Medicine and Public Health, Soochow University, Suzhou, China
    Am J Clin Nutr 94:900-5. 2011
    Observational and preclinical studies suggest that dietary fiber intake may reduce the risk of breast cancer, but the results are inconclusive.
  64. ncbi Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma
    Hui Min Chen
    Division of Gastroenterology and Hepatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institution of Digestive Disease, Shanghai, China
    Am J Clin Nutr 97:1044-52. 2013
    ..Accumulating evidence indicates that diet is one of the most important environmental factors involved in the progression from advanced colorectal adenoma (A-CRA) to colorectal cancer...
  65. ncbi Digestibility of dietary fiber in distillers coproducts fed to growing pigs
    P E Urriola
    Department of Animal Sciences, University of Illinois, Urbana, Illinois 61801, USA
    J Anim Sci 88:2373-81. 2010
    ..was to measure the apparent ileal digestibility (AID) and the apparent total tract digestibility (ATTD) of dietary fiber in different sources of distillers dried grains with solubles (DDGS) and to calculate hindgut fermentation of ..
  66. pmc Phylogenetic characterization of fecal microbial communities of dogs fed diets with or without supplemental dietary fiber using 454 pyrosequencing
    Ingmar S Middelbos
    Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America
    PLoS ONE 5:e9768. 2010
    ..This work aimed to use 16S rDNA tag pyrosequencing to phylogenetically characterize hindgut microbiome in dogs and determine how consumption of dietary fiber affects community structure.
  67. ncbi Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
    Aurelien Trompette
    Faculty of Biology and Medicine, University of Lausanne, Service de Pneumologie, BH19 206 Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, Switzerland
    Nat Med 20:159-66. 2014
    ..Our results show that dietary fermentable fiber and SCFAs can shape the immunological environment in the lung and influence the severity of allergic inflammation. ..
  68. ncbi A randomized controlled trial of dietary fiber intake on serum lipids
    J Chen
    Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA
    Eur J Clin Nutr 60:62-8. 2006
    ..We examined the effect of dietary fiber intake on serum lipids among persons without hypercholesterolemia.
  69. pmc Prebiotic fiber increases hepatic acetyl CoA carboxylase phosphorylation and suppresses glucose-dependent insulinotropic polypeptide secretion more effectively when used with metformin in obese rats
    Kim A Pyra
    Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada
    J Nutr 142:213-20. 2012
    ..In conclusion, the combined actions of OFS and MET were associated with important interaction effects that have the potential to improve metabolic outcomes associated with obesity...
  70. ncbi Increased prevalence of constipation in pre-school children is attributable to under-consumption of plant foods: A community-based study
    Warren T K Lee
    Division of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK
    J Paediatr Child Health 44:170-5. 2008
    ..To evaluate consumption of foods rich in dietary fibre and its relation to the prevalence of constipation in pre-school children...
  71. ncbi Assessment of dietary adequacy in a remote Inuvialuit population
    E Erber
    Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC, USA
    J Hum Nutr Diet 23:35-42. 2010
    ..The present study aimed to characterise energy, nutrient and food intakes amongst adult Inuvialuit...
  72. ncbi Lupin kernel fiber consumption modifies fecal microbiota in healthy men as determined by rRNA gene fluorescent in situ hybridization
    Stuart C Smith
    School of Exercise and Nutrition Sciences, Deakin University, 221 Burwood Hwy, Burwood, Vic, Australia
    Eur J Nutr 45:335-41. 2006
    ..However, the capacity of lupin kernel fiber (LKFibre), a novel legume-derived food ingredient, to act as a prebiotic and modulate the colonic microbiota in humans needed investigation...
  73. ncbi Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment
    Lee S Gross
    Inter Medic Medical Group, 2630 Bobcat Village Center Road, North Port, FL 34288, USA
    Am J Clin Nutr 79:774-9. 2004
    ....
  74. ncbi Dietary fiber intake and risk of cardiovascular disease in the Japanese population: the Japan Public Health Center-based study cohort
    Y Kokubo
    Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Osaka, Japan
    Eur J Clin Nutr 65:1233-41. 2011
    ..We investigated the association between dietary fiber and the risk of cardiovascular disease (CVD), which we defined as stroke or CHD, in a Japanese population.
  75. ncbi Guar gum consumption increases hepatic nuclear SREBP2 and LDL receptor expression in pigs fed an atherogenic diet
    Todd C Rideout
    Centre for Nutrition Modelling, Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    J Nutr 137:568-72. 2007
    ..We conclude that the hypocholesterolemic effects of GG consumption are related to a reduction in hepatic free cholesterol concentration and associated increases in nuclear active SREBP2 expression and hepatic LDLr abundance...
  76. ncbi A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: the Sysdimet study
    V D F de Mello
    Department of Clinical Nutrition Food and Health Research Centre, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, P O Box 1627, FIN 70211 Kuopio, Finland
    Diabetologia 54:2755-67. 2011
    ..We evaluated whether a diet high in fatty fish, bilberries and wholegrain products (Healthy Diet) improves biomarkers reflecting inflammation and endothelial dysfunction in individuals with impaired glucose metabolism...
  77. ncbi Effect of legumes as part of a low glycemic index diet on glycemic control and cardiovascular risk factors in type 2 diabetes mellitus: a randomized controlled trial
    David J A Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
    Arch Intern Med 172:1653-60. 2012
    ..Yet, to our knowledge, they have never been used specifically to lower the GI of the diet. We have therefore undertaken a study of low-GI foods in type 2 DM with a focus on legumes in the intervention...
  78. ncbi Effect of dietary fiber intake on breast cancer risk according to estrogen and progesterone receptor status
    C X Zhang
    Centre of Research and Promotion of Women s Health, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, People s Republic of China
    Eur J Clin Nutr 65:929-36. 2011
    There is few data on the association between dietary fiber intake and estrogen receptor (ER)/progesterone receptor (PR)-defined breast cancer risk...
  79. pmc TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women
    Marilyn C Cornelis
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 89:1256-62. 2009
    ..Dietary factors that increase the insulin demand might enhance the risk of T2D associated with TCF7L2 variants...
  80. ncbi The effect of a fibre supplement compared to a healthy diet on body composition, lipids, glucose, insulin and other metabolic syndrome risk factors in overweight and obese individuals
    Sebely Pal
    School of Public Health, Curtin Health Innovation Research Institute, ATN Centre for Metabolic Fitness, Curtin University of Technology, GPO Box U1987, Perth, WA, Australia 6485
    Br J Nutr 105:90-100. 2011
    ..However, a high-fibre diet consisting of a psyllium supplement plus fibre from a healthy diet provided the greatest improvements in metabolic syndrome risk factors...
  81. ncbi Nutritional overview on the management of type 2 diabetes and the prevention of its complications
    Kyriaki Pegklidou
    Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
    Curr Diabetes Rev 6:400-9. 2010
    ....
  82. ncbi Phytochemical and dietary fiber components in barley varieties in the HEALTHGRAIN Diversity Screen
    Annica A M Andersson
    Department of Food Science, Swedish University of Agricultural Sciences, P O Box 7051, SE 750 07 Uppsala, Sweden
    J Agric Food Chem 56:9767-76. 2008
    ..studied for their content of tocols, folate, plant sterols, alkylresorcinols, and phenolic acids, as well as dietary fiber components (arabinoxylan and beta-glucan)...
  83. ncbi Lignans are involved in the antitumor activity of wheat bran in colon cancer SW480 cells
    Hongyan Qu
    Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA
    J Nutr 135:598-602. 2005
    ..Inhibition of cancer cell growth by lignan metabolites seems to be mediated by cytostatic and apoptotic mechanisms...
  84. ncbi Viscous dietary fiber reduces adiposity and plasma leptin and increases muscle expression of fat oxidation genes in rats
    Ajmila Islam
    Department of Food Science and Nutrition, University of Minnesota, St Paul, Minnesota, USA
    Obesity (Silver Spring) 20:349-55. 2012
    ..To examine this, rats were fed a viscous nonfermentable dietary fiber, hydroxypropyl methylcellulose (HPMC), for 6 weeks...
  85. ncbi Whole grains and CVD risk
    Chris J Seal
    School of Agriculture, Food and Rural Development, University of Newcastle upon Tyne, UK
    Proc Nutr Soc 65:24-34. 2006
    ..Well-controlled intervention studies are needed to provide more detailed mechanistic evidence to support the health claims and findings which can be used to develop effective public health strategies to promote whole-grain consumption...
  86. ncbi Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice
    Frank Isken
    Department of Clinical Nutrition, German Institute of Human Nutrition, Potsdam Rehbruecke, Nuthetal 14558, Germany
    J Nutr Biochem 21:278-84. 2010
    ..The present results show that soluble vs insoluble dietary fiber added to a high-fat, Western-style diet differently affected body weight and estimates of insulin sensitivity ..
  87. ncbi Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 80:1492-9. 2004
    ..However, methods for the assessment of whole-grain intake differ. Furthermore, any additional effects of added bran and germ, which are components of whole grains, have not been reported...
  88. ncbi Dietary fibre, glycaemic response, and diabetes
    Charles S Brennan
    Institute of Food Nutrition and Health, Massey University, Palmerston North, New Zealand
    Mol Nutr Food Res 49:560-70. 2005
    ..The current paper explores the potential use of dietary fibres in the treatment of obesity and diabetes...
  89. ncbi A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning
    Anne C Nilsson
    Division of Applied Nutrition and Food Chemistry, Department of Food Technology, Engineering and Nutrition, Lund University, SE 22100 Lund, Sweden
    J Nutr 140:1932-6. 2010
    ..This mechanism may be one explanation by which whole grain is protective against type 2 diabetes and cardiovascular disease...
  90. ncbi Oat beta-glucan increases postprandial cholecystokinin levels, decreases insulin response and extends subjective satiety in overweight subjects
    Eleanor J Beck
    School of Health Sciences, University of Wollongong, Wollongong, Australia
    Mol Nutr Food Res 53:1343-51. 2009
    ..beta-Glucan improves satiety and release of cholecystokinin is likely to be part of the mechanism. Products with different sources of beta-glucan provide similar benefits but each product requires individual testing...
  91. ncbi The status of vitamins B6, B12, folate, and of homocysteine in geriatric home residents receiving laxatives or dietary fiber
    B Sturtzel
    Department of Nutritional Sciences, University of Vienna, Althanstrasse 14, A 1090 Vienna, Austsria
    J Nutr Health Aging 14:219-23. 2010
    ..Vitamin B12 deficiency as a digestive disorder and constipation as a gastro motility disorder are common in the elderly. Laxative treatment is often chosen without regard for gut health...
  92. ncbi Lipids significantly reduced by diets containing barley in moderately hypercholesterolemic men
    Kay M Behall
    Diet and Human Performance Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    J Am Coll Nutr 23:55-62. 2004
    ..Soluble fiber from oats has been recognized as beneficial in decreasing blood cholesterol levels. Although barley contains high amounts of soluble fiber, it is not consumed as extensively as oats...
  93. ncbi Influence of whole grain barley, whole grain wheat, and refined rice-based foods on short-term satiety and energy intake
    Natalia Schroeder
    Department of Food Science and Nutrition, University of Minnesota, St Paul, MN 55108 1038, USA
    Appetite 53:363-9. 2009
    ....
  94. ncbi Effect of cereal test breakfasts differing in glycemic index and content of indigestible carbohydrates on daylong glucose tolerance in healthy subjects
    Anne C Nilsson
    Division of Applied Nutrition and Food Chemistry, Department of Food Technology, Engineering and Nutrition, Lund University, Sweden
    Am J Clin Nutr 87:645-54. 2008
    ..Frequent hyperglycemic episodes are increasingly being associated with an increased risk of type 2 diabetes and cardiovascular disease...
  95. ncbi Preventing excessive weight gain during pregnancy - a controlled trial in primary health care
    T I Kinnunen
    UKK Institute for Health Promotion Research, Tampere, Finland
    Eur J Clin Nutr 61:884-91. 2007
    ..To investigate whether individual counselling on diet and physical activity during pregnancy can have positive effects on diet and leisure time physical activity (LTPA) and prevent excessive gestational weight gain...
  96. ncbi Greater satiety response with resistant starch and corn bran in human subjects
    Holly J Willis
    Department of Food Science and Nutrition, University of Minnesota, MN 55108, USA
    Nutr Res 29:100-5. 2009
    ..However, we hypothesized that certain types of dietary fiber may enhance satiety more than others...
  97. ncbi Acute ingestion of resistant starch reduces food intake in healthy adults
    Caroline L Bodinham
    Diabetes and Endocrinology, Postgraduate Medical School, University of Surrey, Guildford, Surrey GU2 7WG, UK
    Br J Nutr 103:917-22. 2010
    ..059). These results suggest that consumption of 48 g RS, over a 24-h period, may be useful in the management of the metabolic syndrome and appetite. Further studies are required to determine the exact mechanisms...
  98. ncbi Resistant starch: metabolic effects and potential health benefits
    Janine A Higgins
    University of Colorado Health Sciences Center, Center for Human Nutrition, Box C225, 4200 E Ninth Ave, Denver, CO 80222, USA
    J AOAC Int 87:761-8. 2004
    ..The effects of RS in the large bowel per se are the topic of other reviews and are not addressed in this paper...
  99. ncbi Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinical trials
    Seamus P Whelton
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
    J Hypertens 23:475-81. 2005
    We conducted a meta-analysis of 25 randomized controlled trials published in English-language journals before February 2004, to assess the effect of dietary fiber intake on blood pressure (BP).
  100. ncbi Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Diabetes Care 29:207-11. 2006
    ..To evaluate the dietary predictors for the markers of systemic inflammation and endothelial dysfunction in patients with type 2 diabetes...
  101. ncbi High-fiber rye bread and insulin secretion and sensitivity in healthy postmenopausal women
    Katri S Juntunen
    Department of Clinical Nutrition, University of Kuopio, Kuopio, Finland
    Am J Clin Nutr 77:385-91. 2003
    ..Fiber and whole-cereal intakes may protect against hyperinsulinemia and the risk of type 2 diabetes...

Research Grants63

  1. Investigation on Oligosaccharides as Antimicrobial and Prebiotics
    Peng George Wang; Fiscal Year: 2013
    ..Thus, HMOs are considered as the ''dietary fiber''of human milk...
  2. A simple dietary message to improve dietary quality for metabolic syndrome
    Yunsheng Ma; Fiscal Year: 2012
    ..Results from three recent review articles agreed that adding dietary fiber can aid weight loss and weight loss maintenance;dietary fiber also exerts clinical benefits on several ..
  3. Therapeutic Efficacy of Flaxseed in the Treatment of Ovarian Cancer
    Dale B Hales; Fiscal Year: 2013
    ..Flaxseed is an excellent source of dietary fiber, the OM-3FA alpha-linolenic acid (ALA), and phytoestrogen lignans, which are potent anti-estrogens that have ..
  4. Role of Butyrate in the Gut-Liver Interaction of Ethanol Induced Liver Injury
    GAIL ANN CRESCI; Fiscal Year: 2013
    ..acetate, propionate, and butyrate) are produced in the distal gut through the fermentation of undigested dietary fiber and starch by the commensal gut microbiota...
  5. Impact of Diet on Intestinal Microbiota-Host Dynamics
    Justin Sonnenburg; Fiscal Year: 2013
    ..e., dietary fiber)...
  6. Colon Cell Differentiation: NAB and MUC2 Gene Expression
    Anna Velcich; Fiscal Year: 2009
    ..acid butyrate (NaB), present in high concentrations in the colonic lumen principally from the fermentation of dietary fiber, plays a physiological role in colonic homeostasis...
  7. Critical Role of Mybl2 in Spontaneous and Short-Chain Fatty Acid-Induced Intestin
    MICHAEL JOSEPH PAPETTI; Fiscal Year: 2011
    ..in an immature state in culture yet can be induced by the short chain fatty acid (SCFA) butyrate (a product of dietary fiber fermentation in the human colon), or contact inhibition of growth to differentiate into absorptive (Caco-2), ..
  8. Intestinal Anion Transporters: Function and Regulation
    Pradeep K Dudeja; Fiscal Year: 2013
    ..by applicant): Short chain fatty acids (SCFAs) are produced in the colonic lumen by bacterial fermentation of dietary fiber. SCFAs serve a key role as the metabolic fuel for the colonocytes and are important for the integrity of ..
  9. Gut Microbiota and colonic gene expression: A ligran trial in humans
    Johanna W Lampe; Fiscal Year: 2013
    ..Microbial fermentation of dietary fiber and plant lignans in high-fiber foods produces bioactive endproducts, such as butyrate and enterolignans...
  10. Signaling inputs that maintain the heterogeneity of colorectal cancer cells
    Darina Lazarova; Fiscal Year: 2010
    ..inputs that maintain the heterogeneity of colorectal cancer cells Abstract Butyrate, a fermentation product of dietary fiber in the colon, inhibits the activity of histone deacetylases and induces cell growth arrest, differentiation, ..
  11. Improving health benefits of wheat by increasing resistant starch
    ANN JOAN SLADE; Fiscal Year: 2012
    ..Resistant starch is also correlated with levels of total dietary fiber because it is slowly digested;so increased amylose increases fiber content as well...
  12. The Proyecto Bienestar Laredo: Translating Knowledge and Experience Into Practice
    ROBERTO P TREVINO; Fiscal Year: 2010
    ..program wjth 5 key foci: 1) eat less dietary saturated fat, 2) consume less dietary sugar, 3) eat more dietary fiber, 4) be more physically active and 5) view less T.V...
  13. USC Center for Transdisciplinary Research on Energetics*
    MICHAEL ISAAC GORAN; Fiscal Year: 2010
    ..Project 2 builds on prior USC C-TREC findings and examines the effects of dietary fiber and energy restriction on metabolic and inflammatory profile associated with obesity and obesity-related ..
  14. Mobile e-Health dietary fiber calculator for self-management of IBS
    Lisa A Russell; Fiscal Year: 2012
    ..array of pharmacological and non-pharmacological remedies, including an emphasis on assessing and adjusting dietary fiber intake to regulate bowel function and reduce pain...
  15. Changing behavior by shifting Th1/Th2 balance in the brain
    Gregory G Freund; Fiscal Year: 2010
    ..The most important question that will be answered by our proposed experiments is: Can soluble dietary fiber be used to block activation of the neuroimmune system and mitigate the biobehavioral consequences of brain-..
  16. Clinical Research and Mentoring in Oral Epidemiology
    Kaumudi Joshipura; Fiscal Year: 2009
    ..disease-dental status association is mediated by inflammatory and hemostatic mediators, and by intake of dietary fiber and antioxidants...
  17. Fiber Intake, Gut Bacteria Metabolites and Risk of Colorectal Cancer
    Jiyoung Ahn; Fiscal Year: 2013
    ..2 million new cases annually. Dietary fiber has long been thought to play a protective role in CRC;yet the mechanisms by which fiber protects against CRC ..
  18. Dietary Support for Healthy Digestion in Crohn's Disease
    CAROL S BROTHERTON; Fiscal Year: 2011
    ..Healthy People 2010, "To promote health and reduce chronic disease associated with diet and weight" with specific mention of dietary fiber's critical role in disease prevention and the need to control sugar intake to stay healthy.
  19. LA Sprouts: A garden/nutrition intervention to improve health for high-risk youth
    DONNA D SPRUIJT-METZ; Fiscal Year: 2013
    ..12-week after-school gardening/nutrition intervention ("LA Sprouts") in 4th - 5th grade students improved dietary fiber and vegetable intake, increased preference for fruit and vegetable intake, improved cooking and gardening ..
  20. PHYSIOCHEMICAL EFFECTS OF DIETARY FIBER IN HUMANS
    JUDITH MARLETT; Fiscal Year: 1991
    ..compare the physical properties, chemical compositions and biological effects of three different sources of dietary fiber. Constant daily diets will be used to control for most dietary variables that have made it difficult to ..
  21. Nutrition Program-Caribbean Hispanic elders & diabetes
    ODILIA BERMUDEZ; Fiscal Year: 2003
    ..specific nutrition self-management program designed to improve dietary intake of fruit and vegetables and dietary fiber, which, once incorporated into the diabetes self-management plan of Hispanic elders with diabetes will result ..
  22. BREAST CANCER IN WOMEN OF POLISH ANCESTRY
    Dorothy Pathak; Fiscal Year: 1999
    ..g. glucobrassicins, carotenoids, flavonoids, and antioxidants), and dietary fiber; and 3) increase in intake of meat, meat products and dietary fat; and 4) interaction among the dietary ..
  23. BREAST CANCER IN WOMEN OF POLISH ANCESTRY
    Dorothy Pathak; Fiscal Year: 2001
    ..g. glucobrassicins, carotenoids, flavonoids, and antioxidants), and dietary fiber; and 3) increase in intake of meat, meat products and dietary fat; and 4) interaction among the dietary ..
  24. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2003
    ..In secondary analyses, we will test the hypotheses that the GDAS variant alleles influence the effect of dietary fiber, cholesterol, physical activity, and smoking on CHD...
  25. RCT of the Naturopathic Anti-inflammatory Diet
    Patricia Elmer; Fiscal Year: 2007
    ..effects of the anti-inflammatory diet on inflammatory markers and fasting glucose and insulin, independent of dietary fiber content or weight loss; this latter outcome will be important to control initially since weight loss per se ..
  26. Colon Cancer Prevention Program Project Grant
    M Lance; Fiscal Year: 2009
    ..abstract_text> ..
  27. Impact of Fiber Fermentation on Fecal Incontinence
    Donna Bliss; Fiscal Year: 2007
    ..The long-range objectives of this research are 1) to develop evidenced-based recommendations for using soluble dietary fiber to effectively manage FI and 2) to determine the mechanisms by which soluble dietary fiber improves stool ..
  28. Molecular profiles of colorectal adenomas by array CGH
    Galen Hostetter; Fiscal Year: 2009
    ..Sample size: 50 matched pairs, baseline and recurrent;validation studies, tissue microarrays, FISH and RT-PCR. Bioinformatics/Biostatistics: Nonsupervised data analysis, classifier algorithms, including strong features. ..
  29. NUTRITIONAL INFLUENCES ON COLON CANCER IN THE TAMARIN
    Lynne Ausman; Fiscal Year: 1991
    ..Epidemiologic studies have shown that diets high in fat, cholesterol, and/or meat and low in dietary fiber increase susceptibility to colitis and colon cancer...
  30. NONINVASIVE MEASURES OF STRESS & REPRODUCTIVE STERIODS
    Samuel Wasser; Fiscal Year: 1991
    ..steroid excretion rate, particularly those associated with GI tract transit time; 4) test the influence of dietary fiber on fecal steroid excretion rate and the potential of eliminating any existing effects using nonspecific ..
  31. Targeted delivery of butyrate to the colon in mice
    SHARON FLEMING; Fiscal Year: 2006
    Butyrate is normally produced in the colonic lumen via microbial fermentation of dietary fiber and undigested starch...
  32. SOLUBLE AND INSOLUBLE FIBER DIETS IN HYPERLIPIDEMIA
    David Jenkins; Fiscal Year: 1991
    ..Complete diets metabolically defined will be provided for each dietary fiber period...
  33. Flax: Safety & Efficacy in Reducing Cardiovascular Risk
    Philippe Szapary; Fiscal Year: 2003
    ..abstract_text> ..
  34. ENHANCING CHEMOPREVENTIVE AGENTS IN BEANS
    Uchenna Chukwu; Fiscal Year: 2004
    ..and diabetes - are associated with diets high in calories, fat, saturated fat, cholesterol or too low in dietary fiber. Diet-related health conditions costs society at last $250 billion a year in medical costs and lost ..
  35. CHILDREN'S MULTIMEDIA NUTRITION SIMULATION SOFTWARE
    Michael Anderson; Fiscal Year: 2000
    ..food label, and the cancer and heart disease risks associated with total fat, saturated fat, cholesterol, and dietary fiber; 2) application of Nutrition Facts food labels to behavioral choices, including eating fresh fruits and ..
  36. Plant Foods and Endometrial Cancer Epidemiology
    PAMELA HORN ROSS; Fiscal Year: 2005
    ..a) cruciferous vegetables isothiocyanates, (b) various measures of dietary antioxidants, (c) whole grains / dietary fiber, (d) refined grains / glycemic load, and (e) dietary patterns...
  37. CANCER RISK FACTOR PREVENTION FOR HIGH RISK YOUTH
    Joel Killen; Fiscal Year: 2000
    ..include reducing intake of dietary fat; increasing consumption of low fat foods, fruits, vegetables and dietary fiber; and increasing levels of moderate to vigorous physical activity...
  38. INNER HYGIENE IN MODERN HEALTH CULTURE
    JAMES WHORTON; Fiscal Year: 1990
    ..rise of the concept of diseases of civilization from the late eighteenth century to current theories relating dietary fiber to "Western diseases...
  39. MARYLAND WIC HEALTHY EATING FOR A LIFETIME PROGRAM
    Stephen Havas; Fiscal Year: 2000
    ..nutrition-related risks for cancer by adding two new components: 1) decreasing dietary fat and 2) increasing dietary fiber. The study will extend the highly effective collaboration over the past four years among researchers at the ..
  40. BREATH MARKERS OF COLONIC FERMENTATION
    Loic Le Marchand; Fiscal Year: 1991
    Although there is substantial evidence that dietary fat is positively and dietary fiber negatively associated with colon cancer, some "anomalies" in the epidemiology of this disease have been observed...
  41. Diet and DNA methylation in colon mucosa and adenomas
    Jean Pierre Issa; Fiscal Year: 2007
    ..These studies should provide definitive information on interactions between diet and DNA methylation in human colorectal mucosa and cancer. [unreadable] [unreadable]..
  42. NUTRITIONAL EFFECTS OF PLANT FIBER ON DIGESTION
    Barbara Schneeman; Fiscal Year: 1992
    ..The objective is to investigate some of the basic mechanisms explaining the nutritional and metabolic effects of dietary fiber. Epidemiological evidence has linked a lack of fiber in the diet with several chronic diseases such as ..
  43. Regulation of p21 induction by butyrate in colonic cells
    SHARON FLEMING; Fiscal Year: 2003
    Butyrate is normally produced in the colonic lumen via microbial fermentation of dietary fiber and undigested starch...
  44. COMPANEROS EN LA SALUD--CANCER CONTROL AMONG HISPANICS
    Felipe Castro; Fiscal Year: 1993
    ..those in the control group as indicated by (1) a lower consumption of dietary fat, (2) a higher consumption of dietary fiber, (3) a greater frequency of breast self-examination, and (4) a greater proportion of women (a) seeking ..
  45. INSTITUTIONALIZING DIETARY CHANGES FOR CANCER PREVENTION
    Dennis Frate; Fiscal Year: 1992
    ..application include total caloric reduction (weight loss), a decrease in dietary fat, and an increase in dietary fiber. Our research model centers on implementing dietary change self-help groups within Black churches...
  46. PREVENTION OF OVERWEIGHT IN PRESCHOOL MINORITY CHILDREN
    Marian Fitzgibbon; Fiscal Year: 2002
    ..measure, percent ideal body weight for height (%IBWH), as well as dietary fat intake; and an increase in dietary fiber and fruit and vegetable intake...
  47. INNOVATIVE NUTRITION COMMUNICATION FOR LATINOS
    John Elder; Fiscal Year: 2002
    ..The primary outcome variables for this study are percent calories from dietary fat and number of grams of dietary fiber. Measures will be collected by trained bilingual/bicultural measurement technicians at baseline, immediately ..
  48. EFFECTS OF DIETARY BRAN ON COLON CANCER IN MICE
    NEAL CLAPP; Fiscal Year: 1980
    ..However, any consistent negative correlation of dietary fiber with colon cancer incidences remains to be identified...
  49. MULTIETHNIC/MINORITY COHORT STUDY OF DIET AND CANCER
    Laurence Kolonel; Fiscal Year: 2002
    ..lycopene; breast cancer with the ratio of monounsaturated to saturated/ polyunsaturated fat, components of dietary fiber; colorectal cancer with fat, energy, folate; lung cancer with specific fats, carotenoids) and with foods (e.g...
  50. CANCER PREVENTION PROGRAM IN RURAL CHURCHES
    Richard Winett; Fiscal Year: 2003
    ..Major outcome measures include percent calories from fat, dietary fiber, servings of fruits and vegetables, caloric expenditure in activity, V02Max, and body composition...
  51. Dietary Fiber and Cardiovascular Inflammatory Markers
    Dana King; Fiscal Year: 2006
    The purpose of this research is to investigate the relationship between dietary fiber and cardiovascular inflammatory markers...
  52. Dietary Glycemic Load, Body Weight, and Blood Lipids
    Yunsheng Ma; Fiscal Year: 2005
    ..abstract_text> ..
  53. Serum 25(OH)D, Vitamin D Intake, and Breast Cancer Recurrence in the WHEL Study
    Elizabeth T Jacobs; Fiscal Year: 2010
    ....
  54. Fiber and Colorectal Adenomas: A Pooling Project
    Elizabeth Jacobs; Fiscal Year: 2005
    ..who had consumed higher quantities of fiber prior to entry into the intervention trials, that the source of dietary fiber is an important consideration, and that there may be differential effects of fiber depending on gender and ..