milk

Summary

Summary: The white liquid secreted by the mammary glands. It contains proteins, sugar, lipids, vitamins, and minerals.

Top Publications

  1. ncbi Maternal milk reduces severity of necrotizing enterocolitis and increases intestinal IL-10 in a neonatal rat model
    Bohuslav Dvorak
    Department of Pediatrics and Steele Memorial Children s Research Center, University of Arizona, Tucson, Arizona 85724, USA
    Pediatr Res 53:426-33. 2003
  2. ncbi Diversity of lactic acid bacteria in two Flemish artisan raw milk Gouda-type cheeses
    Koenraad Van Hoorde
    Laboratory of Microbiology, Ghent University, K L Ledeganckstraat 35, B 9000 Gent, Belgium
    Food Microbiol 25:929-35. 2008
  3. pmc Multilocus sequence typing of Campylobacter jejuni isolates from humans, chickens, raw milk, and environmental water in Quebec, Canada
    Simon Levesque
    Department of Microbiology and Infectious Diseases, Faculté de Médecine de l Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, Quebec J1H 5N4, Canada
    J Clin Microbiol 46:3404-11. 2008
  4. ncbi Tolerance to extensively heated milk in children with cow's milk allergy
    Anna Nowak-Wegrzyn
    Department of Pediatrics and Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Allergy Clin Immunol 122:342-7, 347.e1-2. 2008
  5. ncbi Comparison of coconut water, propolis, HBSS, and milk on PDL cell survival
    Velayutham Gopikrishna
    Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College, Maduravoyal, Chennai, India
    J Endod 34:587-9. 2008
  6. pmc Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits
    Ben J Hayes
    Biosciences Research Division, Department of Primary Industries Victoria, Melbourne, Victoria, Australia
    PLoS Genet 6:e1001139. 2010
  7. pmc Genome wide association studies for milk production traits in Chinese Holstein population
    Li Jiang
    Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing, People s Republic of China
    PLoS ONE 5:e13661. 2010
  8. pmc SNP discovery in the bovine milk transcriptome using RNA-Seq technology
    Angela Cánovas
    IRTA, Genetica i Millora Animal, 191 Alcalde Rovira Roure Av, 25198, Lleida, Spain
    Mamm Genome 21:592-8. 2010
  9. ncbi Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition
    Bernard Grisart
    Department of Genetics, Faculty of Veterinary Medicine, University of Liège B43, 4000 Liege, Belgium
    Genome Res 12:222-31. 2002
  10. ncbi Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products
    Xi Chen
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093, China
    Cell Res 20:1128-37. 2010

Detail Information

Publications280 found, 100 shown here

  1. ncbi Maternal milk reduces severity of necrotizing enterocolitis and increases intestinal IL-10 in a neonatal rat model
    Bohuslav Dvorak
    Department of Pediatrics and Steele Memorial Children s Research Center, University of Arizona, Tucson, Arizona 85724, USA
    Pediatr Res 53:426-33. 2003
    Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Maternal milk has been suggested to be partially protective against NEC; however, the mechanisms of this protection are not defined...
  2. ncbi Diversity of lactic acid bacteria in two Flemish artisan raw milk Gouda-type cheeses
    Koenraad Van Hoorde
    Laboratory of Microbiology, Ghent University, K L Ledeganckstraat 35, B 9000 Gent, Belgium
    Food Microbiol 25:929-35. 2008
    ..electrophoresis (PCR-DGGE) was used to study the diversity of lactic acid bacteria (LAB) in two Flemish artisan raw milk Gouda-type cheeses. In parallel, conventional culturing was performed...
  3. pmc Multilocus sequence typing of Campylobacter jejuni isolates from humans, chickens, raw milk, and environmental water in Quebec, Canada
    Simon Levesque
    Department of Microbiology and Infectious Diseases, Faculté de Médecine de l Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, Quebec J1H 5N4, Canada
    J Clin Microbiol 46:3404-11. 2008
    ..typing (MLST) and analysis of the flaA short variable repeat (SVR), to 289 isolates (163 human, 56 chicken, 34 raw milk, and 36 environmental water isolates) collected in the province of Québec, Canada, over 3 years; in addition, the ..
  4. ncbi Tolerance to extensively heated milk in children with cow's milk allergy
    Anna Nowak-Wegrzyn
    Department of Pediatrics and Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Allergy Clin Immunol 122:342-7, 347.e1-2. 2008
    Cow's milk allergy is the most common childhood food allergy...
  5. ncbi Comparison of coconut water, propolis, HBSS, and milk on PDL cell survival
    Velayutham Gopikrishna
    Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College, Maduravoyal, Chennai, India
    J Endod 34:587-9. 2008
    ..of a new storage medium, coconut water, in comparison with propolis, Hank's balanced salt solution (HBSS), and milk in maintaining viable periodontal ligament (PDL) cells on simulated avulsed teeth...
  6. pmc Genetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits
    Ben J Hayes
    Biosciences Research Division, Department of Primary Industries Victoria, Melbourne, Victoria, Australia
    PLoS Genet 6:e1001139. 2010
    ..A second trait, fat concentration in milk, had one locus of large effect and a host of loci with very small effects...
  7. pmc Genome wide association studies for milk production traits in Chinese Holstein population
    Li Jiang
    Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing, People s Republic of China
    PLoS ONE 5:e13661. 2010
    ..GWAS) based on high throughput SNP genotyping technologies open a broad avenue for exploring genes associated with milk production traits in dairy cattle...
  8. pmc SNP discovery in the bovine milk transcriptome using RNA-Seq technology
    Angela Cánovas
    IRTA, Genetica i Millora Animal, 191 Alcalde Rovira Roure Av, 25198, Lleida, Spain
    Mamm Genome 21:592-8. 2010
    ..The objective of this study was to perform a SNP discovery analysis in the milk transcriptome using RNA-Seq...
  9. ncbi Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition
    Bernard Grisart
    Department of Genetics, Faculty of Veterinary Medicine, University of Liège B43, 4000 Liege, Belgium
    Genome Res 12:222-31. 2002
    We recently mapped a quantitative trait locus (QTL) with a major effect on milk composition--particularly fat content--to the centromeric end of bovine chromosome 14...
  10. ncbi Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products
    Xi Chen
    Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093, China
    Cell Res 20:1128-37. 2010
    Recent baby formula milk powder contamination incidents have shown that the classic markers or standards in milk quality control are insufficient in identifying "manipulated" poor-quality milk...
  11. pmc Milk and dairy consumption and incidence of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies
    Sabita S Soedamah-Muthu
    Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Am J Clin Nutr 93:158-71. 2011
    ..The consumption of dairy products may influence the risk of cardiovascular disease (CVD) and total mortality, but conflicting findings have been reported...
  12. ncbi Isolation of bovine milk-derived microvesicles carrying mRNAs and microRNAs
    Taketoshi Hata
    Department of Life Sciences, Graduate School of Bioresources, Mie University, Tsu 514 8507, Japan
    Biochem Biophys Res Commun 396:528-33. 2010
    ..and ultracentrifugation, we could isolate microvesicles with approximately 100 nm in diameter from bovine milk. We also found that approximately 1700 and 1000 ng of total RNA, in which small RNAs were major components, was ..
  13. ncbi A validated genome-wide association study in 2 dairy cattle breeds for milk production and fertility traits using variable length haplotypes
    J E Pryce
    Biosciences Research Division, Department of Primary Industries Victoria, Bundoora 3083, Australia
    J Dairy Sci 93:3331-45. 2010
    ..Previously identified mutations affecting milk production traits were confirmed...
  14. pmc Transcriptome profiling of bovine milk oligosaccharide metabolism genes using RNA-sequencing
    Saumya Wickramasinghe
    Department of Animal Science, University of California Davis, Davis, California, United States of America
    PLoS ONE 6:e18895. 2011
    This study examines the genes coding for enzymes involved in bovine milk oligosaccharide metabolism by comparing the oligosaccharide profiles with the expressions of glycosylation-related genes...
  15. pmc The consumption of milk and dairy foods and the incidence of vascular disease and diabetes: an overview of the evidence
    Peter C Elwood
    Department of Primary Care and Public Health, Cardiff University, University Hospital of Wales, Cardiff, UK
    Lipids 45:925-39. 2010
    The health effects of milk and dairy food consumption would best be determined in randomised controlled trials. No adequately powered trial has been reported and none is likely because of the numbers required...
  16. ncbi DGAT1 underlies large genetic variation in milk-fat composition of dairy cows
    A Schennink
    Animal Breeding and Genomics Centre, Wageningen University, 6700 AH Wageningen, The Netherlands
    Anim Genet 38:467-73. 2007
    Dietary fat may play a role in the aetiology of many chronic diseases. Milk and milk-derived foods contribute substantially to dietary fat, but have a fat composition that is not optimal for human health...
  17. ncbi Lysostaphin expression in mammary glands confers protection against staphylococcal infection in transgenic mice
    D E Kerr
    Department of Animal Sciences, University of Vermont, Burlington, VT 05405, USA
    Nat Biotechnol 19:66-70. 2001
    ..dairy animals, we report the generation of transgenic mice that secrete a potent anti-staphylococcal protein into milk. The protein, lysostaphin, is a peptidoglycan hydrolase normally produced by Staphylococcus simulans...
  18. ncbi Genome-wide association mapping in Norwegian Red cattle identifies quantitative trait loci for fertility and milk production on BTA12
    H G Olsen
    Centre for Integrative Genetics, Norwegian University of Life Sciences, N 1432 Aas, Norway
    Anim Genet 42:466-74. 2011
    ..result was an association for non-return rate in heifers in a region of BTA12 where several associations for milk production traits have previously been found...
  19. ncbi Epigenetic regulation of milk production in dairy cows
    Kuljeet Singh
    AgResearch Ltd, Ruakura Research Centre, Hamilton, 3240, New Zealand
    J Mammary Gland Biol Neoplasia 15:101-12. 2010
    It is well established that milk production of the dairy cow is a function of mammary epithelial cell (MEC) number and activity and that these factors can be influenced by diverse environmental influences and management practises (..
  20. ncbi Synergy between the phage endolysin LysH5 and nisin to kill Staphylococcus aureus in pasteurized milk
    Pilar Garcia
    Instituto de Productos Lacteos de Asturias, Spain
    Int J Food Microbiol 141:151-5. 2010
    ..The synergy observed in vitro was confirmed in challenge assays in pasteurized milk contaminated with S. aureus Sa9...
  21. ncbi Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters
    Joseph W Hartman
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada
    Am J Clin Nutr 86:373-81. 2007
    Acute consumption of fat-free fluid milk after resistance exercise promotes a greater positive protein balance than does soy protein.
  22. ncbi Gluconeogenesis in dairy cows: the secret of making sweet milk from sour dough
    Jörg R Aschenbach
    Department of Veterinary Medicine, Institute of Veterinary Physiology, Free University of Berlin, Berlin, Germany
    IUBMB Life 62:869-77. 2010
    ..An improved understanding of the complex mechanisms underlying gluconeogenesis may further improve our options to enhance the postpartum health status of dairy cows...
  23. pmc Effects of soft drink consumption on nutrition and health: a systematic review and meta-analysis
    Lenny R Vartanian
    Department of Psychology, Yale University, New Haven, Conn 06520 8205, USA
    Am J Public Health 97:667-75. 2007
    ..Soft drink intake also was associated with lower intakes of milk, calcium, and other nutrients and with an increased risk of several medical problems (e.g., diabetes)...
  24. ncbi Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers
    J Z Xiao
    Food Research and Development Laboratory, Morinaga Milk Industry Co, Ltd, Zama 228 8583, Japan
    J Dairy Sci 86:2452-61. 2003
    The effects of milk products fermented by Bifidobacterium longum strain BL1, a probiotic strain, on blood lipids in rats and humans were studied...
  25. ncbi The effect of hydrolyzed cow's milk formula for allergy prevention in the first year of life: the German Infant Nutritional Intervention Study, a randomized double-blind trial
    Andrea von Berg
    Research Institute for Prevention of Allergies and Airway Diseases, Department of Paediatrics, Marien Hospital Wesel, Wesel, Germany
    J Allergy Clin Immunol 111:533-40. 2003
    ..The potential of extensively or partially hydrolyzed formulas to reduce the risks for allergies is controversial...
  26. ncbi Survey of the incidence and aetiology of mastitis on dairy farms in England and Wales
    A J Bradley
    School of Clinical Veterinary Science, University of Bristol, Langford
    Vet Rec 160:253-7. 2007
    ..mastitis was carried out on 97 dairy farms in England and Wales, selected at random from members of a national milk recording scheme...
  27. pmc Gene networks driving bovine milk fat synthesis during the lactation cycle
    Massimo Bionaz
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, 61801 Illinois, USA
    BMC Genomics 9:366. 2008
    The molecular events associated with regulation of milk fat synthesis in the bovine mammary gland remain largely unknown...
  28. pmc Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content
    Andreas Winter
    Lehrstuhl für Tierzucht der Technischen Universität München, 85350 Freising Weihenstephan, Germany
    Proc Natl Acad Sci U S A 99:9300-5. 2002
    ..gene for lactation traits after studies indicated that mice lacking both copies of DGAT1 are completely devoid of milk secretion, most likely because of deficient triglyceride synthesis in the mammary gland...
  29. ncbi Dissociation of the glycaemic and insulinaemic responses to whole and skimmed milk
    Garrett Hoyt
    Department of Health and Exercise Science, Fort Collins, CO 80523, USA
    Br J Nutr 93:175-7. 2005
    ..A single study, examining whole milk and fermented milk products made from whole milk, recently reported a large dissociation between the GI and ..
  30. ncbi The survival advantage of milk and dairy consumption: an overview of evidence from cohort studies of vascular diseases, diabetes and cancer
    Peter C Elwood
    Department of Epidemiology, Statistics and Public Health, Cardiff University, Nutritional Sciences Research Unit, School of Agriculture, Policy and Development, University of Reading, Cardiff, United Kingdom
    J Am Coll Nutr 27:723S-34S. 2008
    To conduct a detailed evaluation, with meta-analyses, of the published evidence on milk and dairy consumption and the incidence of vascular diseases and diabetes...
  31. ncbi Milk consumption during pregnancy is associated with increased infant size at birth: prospective cohort study
    Sjurdur F Olsen
    Department of Epidemiology, Institute of Public Health, University of Aarhus, Aarhus, Denmark
    Am J Clin Nutr 86:1104-10. 2007
    Cow milk contains many potentially growth-promoting factors.
  32. ncbi Dietary arginine supplementation enhances the growth of milk-fed young pigs
    Sung Woo Kim
    Department of Animal and Food Sciences, Texas Tech University, Lubbock, TX 79409 2141, USA
    J Nutr 134:625-30. 2004
    ..2, or 0.4% L-arginine (on the basis of milk replacer powder). Each milk feeder was assigned to 1 dietary treatment. Fresh liquid milk replacer (18...
  33. ncbi Milk products, insulin resistance syndrome and type 2 diabetes
    Angelo Tremblay
    Laval University, Quebec City, Quebec G1K 7P4, Canada
    J Am Coll Nutr 28:91S-102S. 2009
    ..Overall, the intake of low-fat dairy products is a feature of a healthy dietary pattern which has been shown to contribute to a significant extent to the prevention of IRS...
  34. pmc A milk-free diet downregulates folate receptor autoimmunity in cerebral folate deficiency syndrome
    Vincent T Ramaekers
    Department of Paediatric Neurology, Centre Hospitalier Universitaire, Liege, Belgium
    Dev Med Child Neurol 50:346-52. 2008
    ..Autoantibody crossreactivity with milk FR from different species prompted us to test the effect of a milk-free diet...
  35. pmc A large-scale distribution of milk-based fortified spreads: evidence for a new approach in regions with high burden of acute malnutrition
    Isabelle Defourny
    Medecins Sans Frontieres, Paris, France
    PLoS ONE 4:e5455. 2009
    ..In high burden regions for malnutrition, the treatment of individual children is limited by available resources. Here, we evaluate a large-scale distribution of a nutritional supplement on the prevention of wasting...
  36. pmc Molecular epidemiology of mastitis pathogens of dairy cattle and comparative relevance to humans
    Ruth N Zadoks
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik EH26 0PZ, UK
    J Mammary Gland Biol Neoplasia 16:357-72. 2011
    ..In this review, we summarize knowledge gleaned from two decades of molecular epidemiological studies of mastitis pathogens in dairy cattle and discuss aspects of comparative relevance to human medicine...
  37. pmc Transcriptional profiling of bovine milk using RNA sequencing
    Saumya Wickramasinghe
    Department of Animal Science, University of California Davis, CA, 95616 8521, USA
    BMC Genomics 13:45. 2012
    Cow milk is a complex bioactive fluid consumed by humans beyond infancy. Even though the chemical and physical properties of cow milk are well characterized, very limited research has been done on characterizing the milk transcriptome...
  38. pmc Genome-wide association of milk fatty acids in Dutch dairy cattle
    Aniek C Bouwman
    Animal Breeding and Genomics Centre, Wageningen University, Wageningen, The Netherlands
    BMC Genet 12:43. 2011
    Identifying genomic regions, and preferably individual genes, responsible for genetic variation in milk fat composition of bovine milk will enhance the understanding of biological pathways involved in fatty acid synthesis and may point to ..
  39. pmc Sheep with scrapie and mastitis transmit infectious prions through the milk
    Ciriaco Ligios
    Istituto Zooprofilattico Sperimentale della Sardegna, Sassari, Italy
    J Virol 85:1136-9. 2011
    ..Here, we show that sheep with scrapie and lentiviral mastitis secrete prions into the milk and infect nearly 90% of naïve suckling lambs...
  40. ncbi Milk protein intake, the metabolic-endocrine response, and growth in infancy: data from a randomized clinical trial
    Piotr Socha
    Children s Memorial Health Institute, Warsaw, Poland
    Am J Clin Nutr 94:1776S-1784S. 2011
    ..Protein intake in early infancy has been suggested to be an important risk factor for later obesity, but information on potential mechanisms is very limited...
  41. ncbi Characteristics of Shiga toxin-producing Escherichia coli from meat and milk products of different origins and association with food producing animals as main contamination sources
    Annett Martin
    Epidemiology, Biostatistics and Mathematical Modelling, Scientific Services, Unit 33, Federal Institute for Risk Assessment Bundesinstitut für Riskobewertung BfR, Diedersdorfer Weg 1, D 12277 Berlin, Germany
    Int J Food Microbiol 146:99-104. 2011
    ..Significant associations (p<0.001) were found for stx1 and for stx2 with bovine meat and milk products. The stx2e gene was significantly (p<0.001) associated with STEC from pork and wild boar meat...
  42. pmc Bacteroides in the infant gut consume milk oligosaccharides via mucus-utilization pathways
    Angela Marcobal
    Department of Microbiology and Immunology, Stanford School of Medicine, CA 94305, USA
    Cell Host Microbe 10:507-14. 2011
    ..Nursing infants consume human milk oligosaccharides (HMOs) that pass undigested to the distal gut, where they may be digested by microbes...
  43. ncbi Mammary odor cues and pheromones: mammalian infant-directed communication about maternal state, mammae, and milk
    Benoist Schaal
    Research Group in Developmental Ethology and Cognitive Psychology, Center for Taste and Smell Science, CNRS, Dijon, France
    Vitam Horm 83:83-136. 2010
    ..and any mean to alleviate their localization effort and accelerate acceptance to orally grasp a nipple and ingest milk should have had advantageous consequences over evolutionary time...
  44. pmc Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes
    Patrick Veiga
    Harvard School of Public Health, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 107:18132-7. 2010
    ..Here, we show that colitis improved in T-bet(-/-)Rag2(-/-) mice that consumed a fermented milk product containing Bifidobacterium animalis subsp. lactis DN-173 010 strain...
  45. pmc Milk, coronary heart disease and mortality
    A R Ness
    Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 55:379-82. 2001
    To study the association between reported milk consumption and cardiovascular and all cause mortality.
  46. ncbi Milk consumption is a risk factor for prostate cancer in Western countries: evidence from cohort studies
    Li Qiang Qin
    Department of Social Medicine and Health Education, School of Public Health, Peking University, Xueyuan Road 38, Haidian District, Beijing, 100083, China
    Asia Pac J Clin Nutr 16:467-76. 2007
    We have previously found a positive association between milk consumption and prostate cancer risk using meta-analysis to analyze published case-control studies...
  47. ncbi Severity of E. coli mastitis is mainly determined by cow factors
    Christian Burvenich
    Mammary gland and Mastitis Research Centre, Department of Physiology, Biochemistry and Biometrics, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Res 34:521-64. 2003
    ..coli, connection between endotoxins, tumor necrosis factor-alpha and nitric oxide, severity classification of E. coli mastitis, lifespan of neutrophils, host factors that influence severity, tissue damage and production loss...
  48. ncbi Major advances associated with the biosynthesis of milk
    D E Bauman
    Department of Animal Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 89:1235-43. 2006
    ..gland has an incredible level of organization and a remarkable ability to convert circulating nutrients into milk components...
  49. ncbi Compared with casein or total milk protein, digestion of milk soluble proteins is too rapid to sustain the anabolic postprandial amino acid requirement
    Magali Lacroix
    UMR INRA 914, Physiology of Nutrition and Feeding Control Unit, Institut National Agronomique Paris Grignon, Paris, France
    Am J Clin Nutr 84:1070-9. 2006
    The in vivo quality of milk protein fractions has seldom been studied in humans.
  50. ncbi Effects of resistance exercise and fortified milk on skeletal muscle mass, muscle size, and functional performance in middle-aged and older men: an 18-mo randomized controlled trial
    Sonja Kukuljan
    1Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
    J Appl Physiol (1985) 107:1864-73. 2009
    Limited data have suggested that the consumption of fluid milk after resistance training (RT) may promote skeletal muscle hypertrophy...
  51. pmc Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat
    Elayne Hondares
    Departament de Bioquimica i Biologia Molecular, Institut de Biomedicina de la Universitat de Barcelona and CIBER Fisiopatologia de la Obesidad y Nutrición, Barcelona, Catalonia, Spain
    Cell Metab 11:206-12. 2010
    ..We propose that the induction of FGF21 production by the liver mediates direct activation of brown fat thermogenesis during the fetal-to-neonatal transition...
  52. ncbi Immunomodulatory activity of Lactobacillus rhamnosus strains isolated from goat milk: impact on intestinal and respiratory infections
    Susana Salva
    Centro de Referencia para Lactobacilos CERELA CONICET, Chacabuco 145, San Miguel de Tucuman, T4000ILC Tucumán, Argentina
    Int J Food Microbiol 141:82-9. 2010
    ....
  53. pmc APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions
    Chioma M Okeoma
    Department of Microbiology and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Cell Host Microbe 8:534-43. 2010
    ..immunodeficiency virus (HIV) and mouse mammary tumor virus (MMTV), are transmitted from mother to infants through milk. Lymphoid cells and antibodies are thought to provide mammary gland and milk-borne immunity...
  54. ncbi Biomarkers of milk fat and the risk of myocardial infarction in men and women: a prospective, matched case-control study
    Eva Warensjo
    Department of Public Health, Uppsala University, Uppsala, Sweden
    Am J Clin Nutr 92:194-202. 2010
    High intakes of saturated fat have been associated with cardiovascular disease, and milk fat is rich in saturated fat.
  55. ncbi Milk consumption and acne in teenaged boys
    Clement A Adebamowo
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    J Am Acad Dermatol 58:787-93. 2008
    ..We sought to examine the association between dietary dairy intake and teenaged acne among boys...
  56. ncbi Expression of recombinant human factor VIII in milk of several generations of transgenic rabbits
    Peter Chrenek
    Slovak Agricultural Research Centre, Nitra, Slovak Republic
    Transgenic Res 16:353-61. 2007
    ..2% and 59.9% of the hFVIII level in normal human plasma. No apparent effect of secreted rhFVIII on the milk performance of rabbits was observed...
  57. ncbi Expression of the peptidoglycan recognition protein, PGRP, in the lactating mammary gland
    S R Kappeler
    Laboratory of Dairy Science, Institute of Food Science, Swiss Federal Institute of Technology, CH 8092 Zurich, Switzerland
    J Dairy Sci 87:2660-8. 2004
    ..PGRP, known as an intracellular component of neutrophils, has been isolated from camel (Camelus dromedarius) milk by acid precipitation followed by heparin-sepharose affinity chromatography of the supernatant...
  58. pmc Analysis of the N-glycans of recombinant human Factor IX purified from transgenic pig milk
    Geun Cheol Gil
    Department of Chemical and Biomolecular Engineering, University of Nebraska Lincoln, Lincoln, NE 68588, USA
    Glycobiology 18:526-39. 2008
    ..Collectively, these data represent a beginning point for the future investigation of species-specific and tissue/cell-specific differences in N-glycan structures among animals used for transgenic animal bioreactors...
  59. ncbi Whole-genome association study for milk protein composition in dairy cattle
    G C B Schopen
    CRV, PO Box 454, 6800 AL Arnhem, The Netherlands
    J Dairy Sci 94:3148-58. 2011
    Our objective was to perform a genome-wide association study for content in bovine milk of α(S1)-casein (α(S1)-CN), α(S2)-casein (α(S2)-CN), β-casein (β-CN), κ-casein (κ-CN), α-lactalbumin (α-LA), β-lactoglobulin (β-LG), ..
  60. ncbi Field comparison of real-time polymerase chain reaction and bacterial culture for identification of bovine mastitis bacteria
    M T Koskinen
    Finnzymes Oy, Keilaranta 16A, 02150 Espoo, Finland
    J Dairy Sci 93:5707-15. 2010
    ..Comprehensive field comparisons of PCR and traditional milk bacteriology have not been available...
  61. ncbi Effect of long-term consumption of milk supplemented with probiotic lactobacilli and fluoride on dental caries and general health in preschool children: a cluster-randomized study
    C Stecksen-Blicks
    Department of Odontology, Paediatric Dentistry, Faculty of Medicine, Umea University, Umea, Sweden
    Caries Res 43:374-81. 2009
    The aim of this study was to evaluate the effect of milk supplemented with probiotic bacteria and fluoride on caries development and general health in preschool children...
  62. ncbi Association between yogurt, milk, and cheese consumption and common carotid artery intima-media thickness and cardiovascular disease risk factors in elderly women
    Kerry L Ivey
    Curtin Health Innovation Research Institute, School of Public Health, Curtin University of Technology, Perth, Australia
    Am J Clin Nutr 94:234-9. 2011
    ..Despite the contribution of dairy foods to total dietary saturated fat intake, available data indicate that dairy consumption may lower the risk of cardiovascular disease...
  63. pmc Characterization of bioactive recombinant human lysozyme expressed in milk of cloned transgenic cattle
    Bin Yang
    State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, People s Republic of China
    PLoS ONE 6:e17593. 2011
    There is great potential for using transgenic technology to improve the quality of cow milk and to produce biopharmaceuticals within the mammary gland...
  64. ncbi Diversity and evolution of the microbial populations during manufacture and ripening of Casín, a traditional Spanish, starter-free cheese made from cow's milk
    Angel Alegría
    Departamento de Microbiología y Bioquímica, Instituto de Productos Lácteos de Asturias CSIC, Carretera de Infiesto, Asturias, Spain
    Int J Food Microbiol 136:44-51. 2009
    ..As with other starter-free cheeses made from raw milk, the microbial diversity of Casín was shown to be high by both culturing and DGGE analyses...
  65. ncbi Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands
    Ricardo Almon
    Family Medicine Research Centre, Orebro University, Sweden
    Eur J Nutr 49:141-6. 2010
    ..The single nucleotide polymorphism (SNP) LCT -13910 C>T, associated with genetically determined phenotypes of lactase persistence (LP) or non-persistence (LNP), was studied in relation to the metabolic syndrome (MS)...
  66. pmc Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial
    Sunil Sazawal
    Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    PLoS ONE 5:e12167. 2010
    ..children 1-4 years evaluating the effects of micronutrients (especially of zinc and iron) delivered through fortified milk on growth, anemia and iron status markers as part of a four group study design, running two studies simultaneously.
  67. ncbi Establishment and characterization of a lactating bovine mammary epithelial cell model for the study of milk synthesis
    Ke Zhao
    Institute of Dairy Science, MOE Key Laboratory of Molecular Animal Nutrition, Zhejiang University, No 268 Kaixuan Road, Hangzhou 310029, Peoples Republic of China
    Cell Biol Int 34:717-21. 2010
    ..The transcription of the alphas1 casein gene and synthesis of alphas caseins were also detected in the model. Thus, our lactating BMEC model can be an effective model in vitro for studies of milk synthesis in the bovine mammary gland.
  68. pmc Human milk oligosaccharides: every baby needs a sugar mama
    Lars Bode
    Division of Neonatology and Division of Gastroenterology and Nutrition, Department of Pediatrics, University of California, San Diego, CA, USA
    Glycobiology 22:1147-62. 2012
    Human milk oligosaccharides (HMOs) are a family of structurally diverse unconjugated glycans that are highly abundant in and unique to human milk...
  69. ncbi Review: Production and functionality of active peptides from milk
    C Muro Urista
    Department of Chemical Engineering and Investigation, Instituto Tecnológico de Toluca Av Tecnológico s n Ex Rancho la Virgen, Toluca, C P 52140, Mexico
    Food Sci Technol Int 17:293-317. 2011
    In recent years, research on the production of active peptides obtained from milk and their potential functionality has grown, to a great extent...
  70. ncbi Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids
    Wenshan Wang
    Tsinghua Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
    Nat Med 18:235-43. 2012
    ..levels in lactating mammary glands and its deficiency leads to premature pup death as a result of severely reduced milk lipids...
  71. pmc Bacteriophages of lactic acid bacteria and their impact on milk fermentations
    Josiane E Garneau
    Departement de Biochimie, de microbiologie et de bio informatique, Faculte des sciences et de genie, Universite Laval, Quebec City, Quebec, G1V 0A6, Canada
    Microb Cell Fact 10:S20. 2011
    ..For example, phages are the primary cause of fermentation failure in the milk transformation industry...
  72. ncbi Cow's milk-specific immunoglobulin E levels as predictors of clinical reactivity in the follow-up of the cow's milk allergy infants
    M C García-Ara
    Servicio de Alergia, Hospital Infantil Universitario La Paz, Paseo de la Castellana, Madrid, Spain
    Clin Exp Allergy 34:866-70. 2004
    IgE-mediated cow's milk proteins (CMPs) allergy shows a tendency to disappear with age. The sooner tolerance is detected, the earlier the substitute diets can be suspended and the quicker family emotional hardship is alleviated.
  73. ncbi Molecular approaches to analysing the microbial composition of raw milk and raw milk cheese
    Lisa Quigley
    Teagasc, Moorepark Food Research Centre, Fermoy, Cork, Ireland
    Int J Food Microbiol 150:81-94. 2011
    ..PCR) and others, to investigate the diversity, dynamics and identity of microbes in dairy products from raw milk. Here, we will highlight the benefits associated with culture-independent methods which include enhanced ..
  74. pmc Etiology and antimicrobial susceptibility of udder pathogens from cases of subclinical mastitis in dairy cows in Sweden
    Ylva Persson
    Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute, SE 75189 Uppsala, Sweden
    Acta Vet Scand 53:36. 2011
    ..The aim was to investigate the microbial panorama and the occurrence of antimicrobial resistance. Moreover, differences between newly infected cows and chronically infected cows were investigated...
  75. ncbi Determinants of early weaning and use of unmodified cow's milk in infants: a systematic review
    Katrien Wijndaele
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke s Hospital, Hills Rd, Cambridge, CB2 0QQ, United Kingdom
    J Am Diet Assoc 109:2017-28. 2009
    Introduction of complementary foods (weaning) before 4 to 6 months of age and unmodified cow's milk before age 12 months are associated with several health risks...
  76. ncbi Prevention of Coxiella burnetii shedding in infected dairy herds using a phase I C. burnetii inactivated vaccine
    Raphaël Guatteo
    Ecole Nationale Veterinaire de Nantes, UMR 1300 Bio Agression, Epidémiologie et Analyse de Risque, F 44307 Nantes, France
    Vaccine 26:4320-8. 2008
    ..burnetii infection status of the cows was determined on the basis on PCR results on milk, vaginal mucus and faeces and serological analysis performed 2 weeks apart. A cow was considered susceptible (i.e...
  77. pmc Genetic variation among Staphylococcus aureus strains from bovine milk and their relevance to methicillin-resistant isolates from humans
    Eiji Hata
    Research Team for Bacterial Parasitic Diseases, Hokkaido Research Station, National Institute of Animal Health, 4 Hitsujigaoka, Toyohira ku, Sapporo, Hokkaido 062 0045, Japan
    J Clin Microbiol 48:2130-9. 2010
    ..Four methicillin-resistant S. aureus (MRSA) isolates were first confirmed from bovine milk in Japan; these isolates showed geno- and serotypes that were identical or similar to those of human MRSA isolates ..
  78. ncbi Comparison of the cariogenicity of cola, honey, cow milk, human milk, and sucrose
    William H Bowen
    Center for Oral Biology, University of Rochester, Rochester, NY 14642, USA
    Pediatrics 116:921-6. 2005
    ..We chose to examine sucrose, cola drink, honey, human milk, cow milk, and water because some of these have been associated with development of early childhood caries, ..
  79. ncbi Addition of milk prevents vascular protective effects of tea
    Mario Lorenz
    Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie, Charite Universitatsmedizin Berlin, CCM, Chariteplatz 1, D 10117 Berlin, Germany
    Eur Heart J 28:219-23. 2007
    ..However, a question of much debate is whether addition of milk modifies the biological activities of tea...
  80. pmc Multilocus sequence typing of intercontinental bovine Staphylococcus aureus isolates
    E M Smith
    Department of Biological Sciences, University of Warwick, Coventry, UK
    J Clin Microbiol 43:4737-43. 2005
    ..aureus isolates from various sites (milk, teat skin, milking machine unit liners, hands, and bedding) and countries. The theory of the host specificity of S...
  81. ncbi Bovine herpesvirus type 1 (BHV-1) and bovine viral diarrhoea virus (BVDV) infections in dairy herds: self clearance and the detection of seroconversions against a new atypical pestivirus
    Jaruwan Kampa
    Department of Clinical Sciences, P O Box 7054, SLU, SE 75007 Uppsala, Sweden
    Vet J 182:223-30. 2009
    ..Bulk tank milk samples of 186 herds in Thailand were collected four times between 2002 and 2004...
  82. ncbi Lysozyme transgenic goats' milk influences gastrointestinal morphology in young pigs
    Dottie R Brundige
    Department of Animal Science, University of California, Davis, CA 95616, USA
    J Nutr 138:921-6. 2008
    Transgenesis provides a method of expressing novel proteins in milk to increase the functional benefits of milk consumption...
  83. ncbi Invited Review: The role of cow, pathogen, and treatment regimen in the therapeutic success of bovine Staphylococcus aureus mastitis
    H W Barkema
    Dept of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, Canada
    J Dairy Sci 89:1877-95. 2006
    ..of the cow, increasing somatic cell count, increasing duration of infection, increasing bacterial colony counts in milk before treatment, and increasing number of quarters infected...
  84. ncbi Identification of tet(M) in two Lactococcus lactis strains isolated from a Spanish traditional starter-free cheese made of raw milk and conjugative transfer of tetracycline resistance to lactococci and enterococci
    Ana Belén Flórez
    Instituto de Productos Lácteos de Asturias CSIC, Carretera de Infiesto s n, 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 121:189-94. 2008
    ..showed that a tet(M) gene was present in two tetracycline-resistant Lactococcus lactis strains isolated from a raw milk, starter-free cheese...
  85. pmc Milk consumption and the prepubertal somatotropic axis
    Janet W Rich-Edwards
    Connors Center for Women s Health and Gender Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Nutr J 6:28. 2007
    ..We conducted pilot studies in Mongolia and Massachusetts to test the extent to which milk intake raised somatotropic hormone concentrations in prepubertal children.
  86. ncbi Neonatal growth rate and development of mice raised on milk transgenically enriched with omega-3 fatty acids
    Kathleen D Bongiovanni
    Department of Animal Science, University of California Davis, Davis, California 95616, USA
    Pediatr Res 62:412-6. 2007
    ..acid (FA) desaturase gene under the control of a lactation-induced mammary gland promoter were found to produce milk containing significantly elevated levels of alpha-linolenic (ALA) and eicosapentaenoic (EPA) acid...
  87. ncbi Prevalence and persistence of coagulase-negative Staphylococcus species in three dairy research herds
    B E Gillespie
    Department of Animal Science, The University of Tennessee, Knoxville, TN 37996, USA
    Vet Microbiol 134:65-72. 2009
    Coagulase-negative Staphylococcus species (CNS) were isolated from 11.3% (1407 of 12,412) of mammary quarter milk samples obtained from cows in three dairy research herds in 2005...
  88. ncbi Cow milk allergy symptoms are reduced in mice fed dietary synbiotics during oral sensitization with whey
    Bastiaan Schouten
    Pharmaceutical Sciences, Pharmacology and Pathophysiology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht 3584 CA, The Netherlands
    J Nutr 139:1398-403. 2009
    Cow milk allergy is the most common food allergy in children. So far, no effective treatment is available to prevent or cure food allergy...
  89. pmc In vitro amplification of prions from milk in the detection of subclinical infections
    Kevin C Gough
    School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington, Leicestershire, UK
    Prion 3:236-9. 2009
    Prions can be amplified by serial protein misfolding cyclic amplification (sPMCA) from the milk of a high proportion of apparently healthy, scrapie exposed sheep with PRNP genotypes not previously associated with high disease penetrance...
  90. ncbi Body composition and strength changes in women with milk and resistance exercise
    Andrea R Josse
    Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Med Sci Sports Exerc 42:1122-30. 2010
    We aimed to determine whether women consuming fat-free milk versus isoenergetic carbohydrate after resistance exercise would see augmented gains in lean mass and reductions in fat mass similar to what we observed in young men.
  91. pmc Consumption of pasteurized human lysozyme transgenic goats' milk alters serum metabolite profile in young pigs
    Dottie R Brundige
    Department of Animal Science, Meyer Hall, University of California, One Shields Avenue, Davis, CA 95616, USA
    Transgenic Res 19:563-74. 2010
    ..We previously demonstrated that feeding pasteurized transgenic goats' milk expressing human lysozyme (hLZ) can positively impact intestinal morphology and modulate intestinal microbiota ..
  92. pmc The case of botulinum toxin in milk: experimental data
    Oliver G Weingart
    Toxinology Group, Spiez Laboratory, 3700 Spiez, Switzerland
    Appl Environ Microbiol 76:3293-300. 2010
    ..Because of the mild pasteurization process, as well as rapid product distribution and consumption, the milk supply chain has long been considered a potential target of a bioterrorist attack...
  93. pmc Stroke and plasma markers of milk fat intake--a prospective nested case-control study
    Eva Warensjo
    Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden
    Nutr J 8:21. 2009
    ..The fatty acids 15:0 and 17:0 of plasma lipids are biomarkers of milk fat intake...
  94. pmc Casein haplotypes and their association with milk production traits in Norwegian Red cattle
    Heidi Nilsen
    Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, Aas, Norway
    Genet Sel Evol 41:24. 2009
    ..SNP map was constructed for the bovine casein region to identify haplotype structures and study associations with milk traits in Norwegian Red cattle...
  95. pmc How human brucellosis incidence in urban Kampala can be reduced most efficiently? A stochastic risk assessment of informally-marketed milk
    Kohei Makita
    Centre for Infectious Diseases, Division of Pathway Medicine, School of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 5:e14188. 2010
    ..A stochastic risk assessment involving two field surveys (cattle farms and milk shops) and a medical record survey was conducted to assess the risk of human brucellosis infection through ..
  96. pmc Postgenomic analysis of streptococcus thermophilus cocultivated in milk with Lactobacillus delbrueckii subsp. bulgaricus: involvement of nitrogen, purine, and iron metabolism
    Luciana Herve-Jimenez
    INRA, UR477 Biochimie Bacterienne, F 78350 Jouy en Josas, France
    Appl Environ Microbiol 75:2062-73. 2009
    ..thermophilus LMG 18311 in response to the presence of L. delbrueckii subsp. bulgaricus ATCC 11842 during growth in milk at two growth stages. Seventy-seven different genes or proteins (4...
  97. ncbi AluI polymorphism of the bovine growth hormone (GH) gene, resumption of ovarian cyclicity, milk production and loss of body condition at the onset of lactation in dairy cows
    O Balogh
    Faculty of Veterinary Science, Szent Istvan University, 1078 Budapest István u 2, Hungary
    Theriogenology 71:553-9. 2009
    Relationships among GH genotype (AluI polymorphism), parity, metritis and interval from calving to first ovulation, milk production and body condition score (BCS) loss were determined in dairy cows (n=307) on four large-scale farms in ..
  98. ncbi Antimicrobial susceptibility of coagulase-negative Staphylococcus species isolated from bovine milk
    A A Sawant
    Department of Animal Science, The University of Tennessee, Knoxville, TN 37996, USA
    Vet Microbiol 134:73-81. 2009
    Coagulase-negative Staphylococcus (CNS) isolates (n=168) obtained from milk from heifers and dairy cows were screened for minimum inhibitory concentration (MIC) to antimicrobials used commonly for mastitis therapy...
  99. ncbi Assessing the within-herd prevalence of Coxiella burnetii milk-shedder cows using a real-time PCR applied to bulk tank milk
    R Guatteo
    Unit of Animal Health Management, Veterinary School and INRA, BP 40706, 44307 Nantes Cedex 03, France
    Zoonoses Public Health 54:191-4. 2007
    Thirty-seven bulk tank milk (BTM) and individual milk samples of all contributing cows were tested for Coxiella burnetii detection by a real-time PCR assay and used to assess the relationship between the BTM PCR-response and (i) the ..
  100. ncbi Serum amyloid A and TNF alpha in serum and milk during experimental endotoxin mastitis
    Tanja Lehtolainen
    Department of Clinical Veterinary Science, Faculty of Veterinary Medicine, University of Helsinki, 04920 Saarentaus, Finland
    Vet Res 35:651-9. 2004
    ..The severity of each cows systemic and local signs and change in milk appearance were recorded and scored throughout the experiment...
  101. ncbi The predictive value of the skin prick test weal size for the outcome of oral food challenges
    A Verstege
    Department of Pediatric Pneumology and Immunology, University Children s Hospital Charité of Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany
    Clin Exp Allergy 35:1220-6. 2005
    ....

Research Grants68

  1. Correction of glutathione deficiency for treatment of diabetic nephropathy
    Paolo Fanti; Fiscal Year: 2013
    ..N-acetylcysteine (NAC) and the milk thistle (MTh) plant flavonolignans are nutritional supplements with complementary antioxidant properties...
  2. Phosphorylation of FGF23 coordinates crosstalk between the skeleton and kidney
    VINCENT SCOTT TAGLIABRACCI; Fiscal Year: 2013
    ..In fact, the first evidence of protein phosphorylation was in 1883, when the secreted milk protein casein was shown to contain phosphate...
  3. Role of JAK2-PAK1 interaction in prolactin-dependent signaling
    Maria Diakonova; Fiscal Year: 2013
    ..factor able to stimulate mammary gland development and lactation in rabbits, as well as the production of crop milk in pigeons. A few years later, the name prolactin was given, based on its ability to stimulate milk production...
  4. Lactoferrin Enhances Growth and Reduces Nosocomial Infection in Preterm Infants
    Karel Petrak; Fiscal Year: 2009
    ..The study shall consist of four study groups: 1) mother's milk + placebo, 2) mother's milk + TLF, 3) formula feeding + placebo, and 4) formula feeding + TLF...
  5. Metabolic Adapation and Control of Lactation in Humans
    Morey W Haymond; Fiscal Year: 2010
    ..S. and Western Europe. Human milk is universally accepted as the ideal food for infants and breastfeeding has real and potential benefits for the ..
  6. Novel Reagents and Methods for Rapid and High Throughput Detection of Aflatoxin C
    ALAN AI PING WEI; Fiscal Year: 2013
    ..are produced by the fungi Aspergillus, which can contaminate corn, wheat, soy beans, sorghum, peanuts, almonds, and milk. They affect 4.5 billion people worldwide and causes up to 150,000 cases of hepatocellular carcinoma each year...
  7. N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy
    Paolo Fanti; Fiscal Year: 2011
    ..N-acetylcysteine (NAC) and the milk thistle (MTh) plant flavonolignans are nutritional supplements with complementary antioxidant properties...
  8. MECHANISMS OF MILK LIPID SECRETION
    JAMES LEWIS MCMANAMAN; Fiscal Year: 2013
    ..b>Milk lipid secretion is a tightly regulated process requiring synthesis, assembly and transport of triglyceride and ..
  9. Obesity: neural control of body weight and metabolism
    Barry E Levin; Fiscal Year: 2013
    ..This should counteract the effect of lowered levels of these hormones in LL DIO and NL DR dam milk as a postulated mechanism for the obesity resistance and increased leptin sensitivity of LL rearing on DIO rats...
  10. Immune Development: Role of Milk Cell Transfer and Recipient Gender
    Ameae M Walker; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): We have investigated the trans-epithelial transfer of milk immune cells to nursing pups and examined the result of transfer once the recipients were adult...
  11. Expanded Testing Methods for Elements and Metals in Animal Diagnostic Specimens
    Timothy Baszler; Fiscal Year: 2013
    ..To address this gap, existing FDA methodologies must 4 be extended to testing of new matrices such as milk, urine, blood, and tissues...
  12. Evolution of the Immune Response to Cytomegalovirus Transmitted via Breast Milk
    Lynn Puddington; Fiscal Year: 2010
    ..HCMV infection also occurs postnatally in newborns via viral transmission in breast milk. As most of these infants are asymptomatic, it has been proposed that this route of infection could represent a ..
  13. Evaluating Novel Multi-kinase Peptide Inhibitors as a Treatment for Rheumatoid Ar
    DAVID MEN HWEI TSAI; Fiscal Year: 2013
    ..We have isolated a novel milk peptide mixture (AX-3) that inhibits the tyrosine kinase activity of epidermal growth factor receptor (EGFR), ..
  14. Flame Retardant and Adverse Perinatal Outcome (FRAPO)
    Morgan R Peltier; Fiscal Year: 2013
    ..As a result, North Americans have the highest blood and breast milk concentrations of PBDEs anywhere in the world. PBDEs are present in the plasma of almost all pregnant women...
  15. DHA attenuates Inflammatory Responses Through Altering RAGE Signaling
    LYNETTE KAY ROGERS; Fiscal Year: 2013
    ..to this accretion and are often not provided "pre-formed" DHA in parenteral nutrition or receive low levels in milk from human milk banks...
  16. Diet Quality and CVD Risk Factors in a Family Based Weight Management Study
    Alice H Lichtenstein; Fiscal Year: 2013
    ..increasing highly pigmented fruit and vegetable, and fish intake;substituting non-fat and low-fat for full-fat milk and dairy products;and reducing meat, fried food and savory snack intakes...
  17. NATIONAL CHILDREN'S STUDY - CACHE COUNTY STUDY CENTER
    Edward Clark; Fiscal Year: 2012
    ..cord and placental tissues, and meconium collected at/around the time of delivery;vaginal swabs, and breast milk from mothers. Anticipated environmental samples include air, dust, soil, food, and water ...
  18. Lysosomal phospholipase A2 in autoimmune disease
    JAMES ALAN SHAYMAN; Fiscal Year: 2013
    ..Examples include the milk fat globule-EGF factor 8 and the c-mer proto-oncogene tyrosine kinase...
  19. Low level exposure to PBDEs: testing the hormetic and epigenetic hypotheses
    Lucio G Costa; Fiscal Year: 2013
    ..environment, PBDEs have become persistent organic pollutants, and have also been detected in human blood and breast milk. Body burden of PBDEs in humans in North America is much higher than in the rest of the world, and it is highest in ..
  20. Detection of engineered nanomaterials in drinking water, food, commercial product
    Paul K Westerhoff; Fiscal Year: 2010
    ..food, consumer products and biological fluids (including whole blood, blood plasma, blood serum, urine and human milk). Our team has extensive experience in the analysis of manmade pollutants in these matrices...
  21. Iodine Nutrition and Thyroid Disease During Pregnancy and Lactation
    ANGELA MEI TIN LEUNG; Fiscal Year: 2013
    ..The impact of breast milk iodine levels on infant thyroid function is unknown...
  22. Investigation on Oligosaccharides as Antimicrobial and Prebiotics
    Peng George Wang; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Human milk oligosaccharides (HMOs) have been thought to play a role in the development of specific intestinal flora in breast-fed infants for many years...
  23. Lactoferrin for Immunomodulation of Systemic Inflammatory Response Syndrome
    Marian L Kruzel; Fiscal Year: 2011
    ..Focus will be made on utility of rhLF, with dose range comparisons made to commercially available human milk- and neutrophil-derived lactoferrins...
  24. The upper airway and the Sudden Infant Death Syndrome
    Donald Bartlett; Fiscal Year: 2012
    ..The laryngeal chemoreflex (LCR)-apnea and swallowing in response to intralaryngeal water, milk or other fluids-is more prominent in newborn animals and human infants than in adults and, therefore, has long been ..
  25. Quantitation of Tocopherol Metabolism in Humans
    ANDREW JOSEPH CLIFFORD; Fiscal Year: 2010
    ..5 g olive oil and 30 g skim milk. We will follow the 14C tracer over a 60-day period...
  26. AGE-RELATED ALTERATION OF LEYDIG CELL REDOX ENVIRONMENT A RISK FACTOR FOR SUSCEPT
    Kassim Traore; Fiscal Year: 2013
    ..g. IV drip bags), which result in measurable levels of DEHP and metabolites in blood, urine, semen and breast milk. Exposure to mono-(2-ethylhexyl) phthalate (MEHP), the active metabolite of DEHP, was shown to inhibit LH-..
  27. Novel High Affinity and Long-Acting Bovine FSH Analogs for Veterinary Superovulat
    BRUCE DALE WEINTRAUB; Fiscal Year: 2012
    ..Bovine ovarian superovulation is the current state-of-the-art method employed worldwide to maintain and improve milk and beef production through genetic selection of the best quality breeders and best quality embryos for transfer...
  28. Maternal Hyperinsulinemia and Fetal Programming
    Mulchand S Patel; Fiscal Year: 2011
    ..New born rat pups will be artificially reared on a high carbohydrate milk formula for generation of 1-HC rats. 2-HC rats will be generated by breeding 1-HC female rats with normal male rats...
  29. ANALYSIS OF CHROMATIN REMODELING IN MAMMARY GLAND DEVELOPMENT USING TILING ARRAYS
    Monique Rijnkels; Fiscal Year: 2009
    ..As milk protein genes are expressed in functionally differentiated mammary epithelial cells, our studies will focus on the ..
  30. Ethical and Legal Challenges in Communicating Individual Biomonitoring and Person
    Rachel Morello-Frosch; Fiscal Year: 2013
    ..contaminants may affect health, researchers increasingly turn to biomonitoring of human blood, urine, breast milk, and other tissues, and to sampling in personal spaces, such as testing dust and air in homes...
  31. Targeting the oral cavity epithelium for inducing mucosal immunity against HIV
    Harvinder Singh Gill; Fiscal Year: 2012
    ..infected with human immunodeficiency virus (HIV) due to transmission of HIV from mother to child through the breast milk. Our goal is to induce HIV-neutralizing antibodies in the saliva to enable neutralization of HIV in the milk and ..
  32. NATIONAL CHILDREN'S STUDY SUPPORT
    Betty Wood; Fiscal Year: 2013
    ..cord and placental tissues, and meconium collected at/around the time of delivery;vaginal swabs, and breast milk from mothers. Anticipated environmental samples include air, dust, soil, food, and water...
  33. NATIONAL CHILDREN'S STUDY SUPPORT
    Betty Wood; Fiscal Year: 2012
    ..cord and placental tissues, and meconium collected at/around the time of delivery;vaginal swabs, and breast milk from mothers. Anticipated environmental samples include air, dust, soil, food, and water...
  34. NATIONAL CHILDREN'S STUDY SUPPORT
    Betty Wood; Fiscal Year: 2011
    ..cord and placental tissues, and meconium collected at/around the time of delivery;vaginal swabs, and breast milk from mothers. Anticipated environmental samples include air, dust, soil, food, and water...
  35. Causes of rotavirus vaccine failure in Zambian children
    Roma Chilengi; Fiscal Year: 2013
    ..and high level maternal immunity that is passed to the fetus/newborn transplacentally and/or through breast milk. Specific hypotheses include: (i) High-level rotavirus-specific maternal immunity (in the form of anti-rotavirus ..
  36. Planning a clinical trial of Flash-heated breast milk to decrease morbidity, impr
    Caroline J Chantry; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Planning an efficacy trial of Flash-heated breast milk to decrease morbidity, improve growth, and reduce HIV transmission in HIV-exposed infants The World Health Organization recommends that HIV ..
  37. Evaluating Economic Subsidies To Improve Dietary Intake Among Low Income Families
    Marian L Fitzgibbon; Fiscal Year: 2010
    ..Among the revisions are changes in the fat content (e.g., reduced fat milk) and the fiber content (e.g...
  38. NATIONAL CHILDREN'S STUDY -CLINICAL BIOLOGICAL ANALYSIS
    VELAZQUEZ FRANCISCO; Fiscal Year: 2011
    ..cord and placental tissues, and meconium collected at/around the time of delivery;vaginal swabs, and breast milk from mothers. Anticipated environmental samples include air, dust, soil, food, and water...
  39. QTL and QTL Genes Underlying Lactation Performance
    Darryl L Hadsell; Fiscal Year: 2010
    ..The most common reason cited for early cessation of breastfeeding is insufficient milk volume...
  40. Tsetse Fecundity Reduction for Trypanosomiasis Control
    Serap Aksoy; Fiscal Year: 2013
    ..Nutrients are transferred from the mother to offspring by milk secretions generated in a specialized accessory gland called the milk gland...
  41. ERR-gamma-dependent mammary tumorigenesis in response to BPA and a high-fat diet
    Rebecca B Riggins; Fiscal Year: 2010
    ..BPA readily crosses the placental barrier, appears to accumulate in the fetus, and is found in breast milk However, very little is known about the molecular mechanisms that regulate breast cancer development in response to ..
  42. Lipid metabolism during tsetse reproduction
    JOSH B BENOIT; Fiscal Year: 2013
    ..Mothers provide nutrients, directly to their intrauterine progeny via a milk gland and only give birth to 8-10 offspring in their lifetime...
  43. Lactogenic immunity/probiotics: Effect on neonatal gut immunity
    Linda J Saif; Fiscal Year: 2010
    Breast milk contains maternal antibodies (MatAbs) that promote infant health and moderate diarrhea, and soluble immunomediators (TGF2, IL4, sCD14, etc) whose role is largely unexplored...
  44. Children's Exposure to Flame Retardants: Effects on Thyroid Hormone Regulation
    Heather M Stapleton; Fiscal Year: 2012
    ..ages of 0-4 are predicted to have the highest exposure and body burdens of PBDEs due to placental transfer, breast milk ingestion and inadvertent dust ingestion...
  45. Effect of a sanitation &nutrition intervention on HIV-exposed infant health
    JEAN HAWES HUMPHREY; Fiscal Year: 2012
    ..promotion of exclusive BF from birth to 6 mo for all infants;promotion of expressed and heat-treated breast milk (no direct BF) for HIV-exposed infants testing PCR-negative at 6 months and continued BF for exposed infants ..
  46. NATIONAL CHILDREN'S STUDY COORDINATING CENTER
    Elaine D Eaker; Fiscal Year: 2009
    ..cord and placental tissues, and meconium collected at/around the time of delivery;vaginal swabs, and breast milk from mothers. Anticipated environmental samples include air, dust, soil, food, and water...
  47. Sugar-sweetened beverage taxes, beverage purchasing patterns, and weight
    Jamie F Chriqui; Fiscal Year: 2013
    ..higher energy intake, reduced vitamin and nutrient intake, reductions in consumption of healthier beverages such as milk, and increased body mass index (BMI), risk of obesity and diabetes...
  48. A Prospective Study of Diet and Prostate Cancer
    Edward Giovannucci; Fiscal Year: 2011
    ..We hypothesize that many of the proposed modifiable factors for prostate cancer (intakes of vitamin D, calcium, milk, antioxidants, n-3 fatty acids, polyunsaturated fat, hyperinsulinemic diets, obesity, anti-inflammatory agents) may ..
  49. A Novel Oral Combination Pediatric HIV and TB Vaccine
    Michelle H Larsen; Fiscal Year: 2012
    A vaccine to prevent mother-to-child-transmission of HIV-1 via breast milk, to which vulnerable infants are repeatedly exposed, is urgently needed in resource-poor countries with limited access to antiretroviral therapy...
  50. Activation of Host-Probiotic Communication by Prebiotic Milk Oligosaccharides
    Helen E Raybould; Fiscal Year: 2012
    ..b>Milk oligosaccharides are naturally evolved prebiotic substrates that facilitate bifidobacterial enrichment and ..
  51. IRS insecticides for malaria control and child neurodevelopment in South Africa
    Brenda Eskenazi; Fiscal Year: 2013
    ..for environmental health science: the use of PBPK models to quantify the relative contributions of in utero, breast milk, and other postnatal environmental exposures in infants, and the use of state-of-the-art epigenetic methods to ..
  52. Mechanisms of Perchlorate-Induced Disruption of Sexual Differentiation
    FRANK ARTHUR VON HIPPEL; Fiscal Year: 2013
    ..toxicant, perchlorate poses a major risk to human health through ingestion of contaminated water, food, and breast milk. Perchlorate is a known endocrine disruptor that competitively inhibits iodide uptake at the Sodium-Iodide ..
  53. Milk osteopontin, a nutritional therapeutic intervention for alcoholic hepatitis
    Natalia Nieto; Fiscal Year: 2013
    ..Vitamin D targets osteopontin via a vitamin D-responsive element in the osteopontin promoter. Milk osteopontin protects the gut by maintaining the epithelial barrier function, providing mucosal defense, preventing ..
  54. Oligosaccharide moieties of human milk glycans that inhibit pathogens
    David S Newburg; Fiscal Year: 2013
    ..that the reduced incidence of enteric diseases in breastfeeding infants is due, in part, to protection by human milk glycans...
  55. Measuring signaling pathway dynamics during tissue growth in hydrogels
    Lonnie D Shea; Fiscal Year: 2013
    ..Normal mammary epithelial cells (MECs) form round acini capable of milk production in permissive environments, whereas the combination of aberrant oncogene activity (e.g...
  56. A Novel Therapy for Septic Shock
    Xiaoling Qiang; Fiscal Year: 2011
    ..Recent evidence shows that the opsonizing protein milk fat globule epidermal growth factor-factor VIII (MFG-E8) is involved in apoptotic cell clearance...
  57. Humanization of hFcRn Mice for Physiological Evaluation of Therapeutic Antibodies
    MICHAEL VAN WILES; Fiscal Year: 2013
    ..FcRn functions across many tissues and is critical for neonatal acquisition of maternal IgG via colostrum and milk, the pulmonary secretion of IgG and bidirectional transport of both IgG and immune complexes across the adult ..
  58. NATIONAL CHILDREN'S STUDY
    William Hogan; Fiscal Year: 2013
    ..cord and placental tissues, and meconium collected at/around the time of delivery;vaginal swabs, and breast milk from mothers. Anticipated environmental samples include air, dust, soil, food, and water...
  59. Milk oligosaccharides, bifidobacteria and intestinal epithelium.
    Maciej Chichlowski; Fiscal Year: 2011
    ..are often enriched in the infant gastrointestinal tract. It has been proposed that human milk oligosaccharides (HMO), a major component of breast milk, are responsible for this enrichment...
  60. DETERMINATION OF A NEW GROWTH FACTOR IN BREAST MILK
    DAVID TAPPER; Fiscal Year: 1992
    ..During our prior granting period, we identified specific growth factor activities in milk of substrains of mice with varying incidences of developing mammary tumor...
  61. Surfaces designed for the quantification of long-chain fatty acids
    STEVEN MEYERS; Fiscal Year: 2009
    ..Yet, the concentration of fatty acids in breast milk is particularly important as breastfeeding is one of the most important contributors to infant health...
  62. Pilot Study on Mammary Expression of Novel Desaturases
    ALISON VAN EENENNAAM; Fiscal Year: 2005
    ..b>Milk fatty acid composition in monogastric mammals is reflective of the dietary fatty acid composition...
  63. Prevention of Overfeeding During Infancy
    Kathryn G Dewey; Fiscal Year: 2010
    ..of a novel nipple that mimics (functionally) the nipple of a human breast and allows the infant to self-regulate milk flow. The second objective is to evaluate the relationship between parental feeding styles and infant intake...
  64. The Effect of PTHrP During Lactation
    John J Wysolmerski; Fiscal Year: 2010
    Reproduction is associated with a remarkable cycle of bone loss and recovery. Newborns depend on milk for all nutrients, including calcium...
  65. Effects of Lactational Exposure to Chromium (VI) on Ovarian Development
    SAKHILA BANU; Fiscal Year: 2010
    ..abnormal menses and have high blood levels of Cr(VI) that can be transported from mother to offspring through milk. If lactating women working in a Cr industry or living in an area exposed to high Cr intake through food or ..