coffee

Summary

Summary: A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.

Top Publications

  1. pmc Chlorogenic acid stimulates glucose transport in skeletal muscle via AMPK activation: a contributor to the beneficial effects of coffee on diabetes
    Khang Wei Ong
    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    PLoS ONE 7:e32718. 2012
  2. pmc Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression
    Nam Joo Kang
    The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
    Carcinogenesis 30:321-30. 2009
  3. doi Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysis
    Rachel Huxley
    The George Institute for International Health, The University of Sydney, Australia
    Arch Intern Med 169:2053-63. 2009
  4. pmc Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee
    Taye H Hamza
    New York State Department of Health Wadsworth Center, Albany, New York, USA
    PLoS Genet 7:e1002237. 2011
  5. pmc Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study
    Rashmi Sinha
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
    Am J Clin Nutr 96:374-81. 2012
  6. pmc Risk of colon cancer and coffee, tea, and sugar-sweetened soft drink intake: pooled analysis of prospective cohort studies
    Xuehong Zhang
    Department of Nutrition, Department of Epidemiology, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 102:771-83. 2010
  7. pmc Ochratoxin A in roasted coffee from French supermarkets and transfer in coffee beverages: comparison of analysis methods
    Mariana Tozlovanu
    Laboratory Chemical Engineering, Department Bioprocess and Microbial System, UMR CNRS INPT UPS 5503, ENSA Toulouse, France
    Toxins (Basel) 2:1928-42. 2010
  8. pmc The impact of climate change on indigenous Arabica coffee (Coffea arabica): predicting future trends and identifying priorities
    Aaron P Davis
    The Herbarium, Royal Botanic Gardens, Kew, Richmond, Surrey, United Kingdom
    PLoS ONE 7:e47981. 2012
  9. pmc Tea, coffee, carbonated soft drinks and upper gastrointestinal tract cancer risk in a large United States prospective cohort study
    J S Ren
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States
    Eur J Cancer 46:1873-81. 2010
  10. doi Coffee and its consumption: benefits and risks
    Masood Sadiq Butt
    National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
    Crit Rev Food Sci Nutr 51:363-73. 2011

Detail Information

Publications353 found, 100 shown here

  1. pmc Chlorogenic acid stimulates glucose transport in skeletal muscle via AMPK activation: a contributor to the beneficial effects of coffee on diabetes
    Khang Wei Ong
    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    PLoS ONE 7:e32718. 2012
    ..Our data demonstrated for the first time that CGA stimulates glucose transport in skeletal muscle via the activation of AMPK. It appears that CGA may contribute to the beneficial effects of coffee on Type 2 diabetes mellitus.
  2. pmc Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression
    Nam Joo Kang
    The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
    Carcinogenesis 30:321-30. 2009
    Caffeic acid (3,4-dihydroxycinnamic acid) is a well-known phenolic phytochemical present in many foods, including coffee. Recent studies suggested that caffeic acid exerts anticarcinogenic effects, but little is known about the underlying ..
  3. doi Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysis
    Rachel Huxley
    The George Institute for International Health, The University of Sydney, Australia
    Arch Intern Med 169:2053-63. 2009
    b>Coffee consumption has been reported to be inversely associated with risk of type 2 diabetes mellitus. Similar associations have also been reported for decaffeinated coffee and tea...
  4. pmc Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee
    Taye H Hamza
    New York State Department of Health Wadsworth Center, Albany, New York, USA
    PLoS Genet 7:e1002237. 2011
    Our aim was to identify genes that influence the inverse association of coffee with the risk of developing Parkinson's disease (PD)...
  5. pmc Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study
    Rashmi Sinha
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
    Am J Clin Nutr 96:374-81. 2012
    b>Coffee and tea are widely consumed globally and are rich sources of potential chemopreventive compounds. Epidemiologic data for coffee and tea intakes in relation to colorectal cancer remain unclear...
  6. pmc Risk of colon cancer and coffee, tea, and sugar-sweetened soft drink intake: pooled analysis of prospective cohort studies
    Xuehong Zhang
    Department of Nutrition, Department of Epidemiology, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 102:771-83. 2010
    The relationships between coffee, tea, and sugar-sweetened carbonated soft drink consumption and colon cancer risk remain unresolved.
  7. pmc Ochratoxin A in roasted coffee from French supermarkets and transfer in coffee beverages: comparison of analysis methods
    Mariana Tozlovanu
    Laboratory Chemical Engineering, Department Bioprocess and Microbial System, UMR CNRS INPT UPS 5503, ENSA Toulouse, France
    Toxins (Basel) 2:1928-42. 2010
    ..These analytical problems will seriously impact the amount of OTA detected, especially at the levels close to the limits from the EU legislation. Underestimation of OTA could be highly dangerous for health...
  8. pmc The impact of climate change on indigenous Arabica coffee (Coffea arabica): predicting future trends and identifying priorities
    Aaron P Davis
    The Herbarium, Royal Botanic Gardens, Kew, Richmond, Surrey, United Kingdom
    PLoS ONE 7:e47981. 2012
    Precise modelling of the influence of climate change on Arabica coffee is limited; there are no data available for indigenous populations of this species...
  9. pmc Tea, coffee, carbonated soft drinks and upper gastrointestinal tract cancer risk in a large United States prospective cohort study
    J S Ren
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States
    Eur J Cancer 46:1873-81. 2010
    The authors investigated the relationship between hot tea, iced tea, coffee and carbonated soft drinks consumption and upper gastrointestinal tract cancers risk in the NIH-AARP Study...
  10. doi Coffee and its consumption: benefits and risks
    Masood Sadiq Butt
    National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
    Crit Rev Food Sci Nutr 51:363-73. 2011
    b>Coffee is the leading worldwide beverage after water and its trade exceeds US $10 billion worldwide...
  11. ncbi Association of coffee and caffeine intake with the risk of Parkinson disease
    G W Ross
    Department of Veterans Affairs, Honolulu 151, PO Box 50188, Honolulu, HI 96850, USA
    JAMA 283:2674-9. 2000
    ..The projected expansion in the next several decades of the elderly population at highest risk for Parkinson disease (PD) makes identification of factors that promote or prevent the disease an important goal...
  12. doi Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis
    Jeffrey W Molloy
    Divison of Gastroenterology and Hepatology, Wilford Hall Medical Center, Lackland Air Force Base, TX, USA
    Hepatology 55:429-36. 2012
    b>Coffee caffeine consumption (CC) is associated with reduced hepatic fibrosis in patients with chronic liver diseases, such as hepatitis C. The association of CC with nonalcoholic fatty liver disease (NAFLD) has not been established...
  13. pmc Association of coffee drinking with total and cause-specific mortality
    Neal D Freedman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    N Engl J Med 366:1891-904. 2012
    b>Coffee is one of the most widely consumed beverages, but the association between coffee consumption and the risk of death remains unclear.
  14. ncbi Coffee, caffeine and blood pressure: a critical review
    M L Nurminen
    Institute of Biomedicine, Department of Pharmacology and Toxicology, University of Helsinki, Finland
    Eur J Clin Nutr 53:831-9. 1999
    We review the published data relating to intake of coffee and caffeine on blood pressure in man. We also refer to studies on the possible mechanisms of actions of these effects of caffeine.
  15. ncbi The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults
    Hiroyasu Iso
    Public Health, Department of Social and Environmental Health, Osaka University and Osaka City University, Suita Shi, Osaka, Japan
    Ann Intern Med 144:554-62. 2006
    In western populations, coffee consumption is associated with a reduced risk for type 2 diabetes; however, the effect of green, black, and oolong teas is unclear.
  16. doi Coffee, tea, and fatal oral/pharyngeal cancer in a large prospective US cohort
    Janet S Hildebrand
    Epidemiology Research Program, American Cancer Society, 250 Williams Street NW, Atlanta, GA 30303, USA
    Am J Epidemiol 177:50-8. 2013
    Epidemiologic studies suggest that coffee intake is associated with reduced risk of oral/pharyngeal cancer...
  17. doi Use of coffee, caffeinated drinks and caffeine tablets for cognitive enhancement in pupils and students in Germany
    A G Franke
    Department of Psychiatry and Psychotherapy, University Medical Centre Mainz, Mainz, Germany
    Pharmacopsychiatry 44:331-8. 2011
    ..There are only few data about substances, prevalence rates and factors associated with CE. The aim of this study was to assess first data about the use of coffee, caffeinated drinks and caffeine tablets for CE at school and university.
  18. ncbi Coffee and health: a review of recent human research
    Jane V Higdon
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Crit Rev Food Sci Nutr 46:101-23. 2006
    b>Coffee is a complex mixture of chemicals that provides significant amounts of chlorogenic acid and caffeine...
  19. doi The effect of coffee on blood pressure and cardiovascular disease in hypertensive individuals: a systematic review and meta-analysis
    Arthur Eumann Mesas
    Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid IdiPAZ, Madrid, Spain
    Am J Clin Nutr 94:1113-26. 2011
    The effect of coffee and caffeine on blood pressure (BP) and cardiovascular disease (CVD) in hypertensive persons is uncertain.
  20. pmc Aging and nocturnal driving: better with coffee or a nap? A randomized study
    Patricia Sagaspe
    Clinique du Sommeil, CHU Pellegrin, Bordeaux, France
    Sleep 30:1808-13. 2007
    To test the effects of coffee and napping on nocturnal driving in young and middle-aged participants.
  21. ncbi Age at menarche in relation to maternal use of tobacco, alcohol, coffee, and tea during pregnancy
    Gayle C Windham
    Division of Environmental and Occupational Disease Control, California Department of Health Services, Oakland, CA, USA
    Am J Epidemiol 159:862-71. 2004
    ..7, 95% CI: 0.91, 3.2), but daughters of coffee consumers did not. These suggestive findings, which merit further investigation, may be related to hormonal effects...
  22. doi Coffee consumption and risk of stroke: a dose-response meta-analysis of prospective studies
    Susanna C Larsson
    Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 17177 Stockholm, Sweden
    Am J Epidemiol 174:993-1001. 2011
    b>Coffee consumption has been inconsistently associated with risk of stroke. The authors conducted a meta-analysis of prospective studies to quantitatively assess the association between coffee consumption and stroke risk...
  23. pmc Coffee, caffeine, and risk of depression among women
    Michel Lucas
    Department of Nutrition, Harvard School of Public Health, and Department of Medicine, Brigham and Women s Hospital, 655 Huntington Ave, Boston, MA 02115, USA
    Arch Intern Med 171:1571-8. 2011
    ..is the world's most widely used central nervous system stimulant, with approximately 80% consumed in the form of coffee. However, studies that analyze prospectively the relationship between coffee or caffeine consumption and ..
  24. pmc A prospective investigation of coffee drinking and endometrial cancer incidence
    Marc J Gunter
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA
    Int J Cancer 131:E530-6. 2012
    b>Coffee drinking may be associated with reduced risk of endometrial cancer; however, prospective data are limited...
  25. ncbi Psychological factors, coffee and risk of diabetes mellitus among middle-aged Japanese: a population-based prospective study in the JPHC study cohort
    Masayuki Kato
    Japan Foundation for Promotion of International Medical Research Cooperation, Tokyo, Japan
    Endocr J 56:459-68. 2009
    ..In addition, inverse association between coffee consumption and the incidence of diabetes which was consistent with other studies was observed.
  26. ncbi The associations of age, lifestyle factors and chronic disease with testosterone in men: the Tromsø Study
    Johan Svartberg
    Department of Medicine, University Hospital of North Norway, N 9038, Tromsø, Norway
    Eur J Endocrinol 149:145-52. 2003
    ....
  27. doi Suppression of the coffee-ring effect by shape-dependent capillary interactions
    Peter J Yunker
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Nature 476:308-11. 2011
    ..This phenomenon, known as the coffee-ring effect, is familiar to anyone who has observed a drop of coffee dry...
  28. ncbi Habitual caffeine intake and the risk of hypertension in women
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    JAMA 294:2330-5. 2005
    ..Caffeine acutely increases blood pressure, but the association between habitual consumption of caffeinated beverages and incident hypertension is uncertain...
  29. ncbi Caffeine content of specialty coffees
    Rachel R McCusker
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, P O Box 100275, Gainesville, Florida 32610 0275, USA
    J Anal Toxicol 27:520-2. 2003
    Caffeine is the world's most widely consumed drug with its main source found in coffee. We evaluated the caffeine content of caffeinated and decaffeinated specialty coffee samples obtained from coffee shops...
  30. ncbi Ochratoxin A-producing Aspergilli in Vietnamese green coffee beans
    S L Leong
    CSIRO Food Science Australia, North Ryde, NSW, Australia
    Lett Appl Microbiol 45:301-6. 2007
    To determine the incidence and severity of infection by ochratoxin A (OA)-producing fungi in Vietnamese green coffee beans.
  31. ncbi Coffee, tea and diabetes: the role of weight loss and caffeine
    J A Greenberg
    Department of Health and Nutrition Sciences, Brooklyn College, City University of New York, Brooklyn, NY 11210, USA
    Int J Obes (Lond) 29:1121-9. 2005
    To assess the effect of weight change on the relationship between coffee and tea consumption and diabetes risk.
  32. doi Measurement of caffeic and ferulic acid equivalents in plasma after coffee consumption: small intestine and colon are key sites for coffee metabolism
    Mathieu Renouf
    Nestle Research Center, Nestec Limited, Vers chez les Blanc, Lausanne, Switzerland
    Mol Nutr Food Res 54:760-6. 2010
    Previous studies on coffee examined absorption of phenolic acids (PA) in the small intestine, but not the contribution of the colon to absorption...
  33. doi Consumption of coffee, green tea, oolong tea, black tea, chocolate snacks and the caffeine content in relation to risk of diabetes in Japanese men and women
    Shino Oba
    Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu1 1 Yanagido, Gifu, Gifu 501 1194, Japan
    Br J Nutr 103:453-9. 2010
    Although the inverse association between coffee consumption and risk of diabetes has been reported numerous times, the role of caffeine intake in this association has remained unclear...
  34. pmc Coffee, tea, and caffeine consumption and incidence of colon and rectal cancer
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, and Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 97:282-92. 2005
    Frequent coffee consumption has been associated with a reduced risk of colorectal cancer in a number of case-control studies. Cohort studies have not revealed such an association but were limited in size...
  35. ncbi Coffee consumption and glucose tolerance status in middle-aged Japanese men
    T Yamaji
    Department of Preventive Medicine, Faculty of Medical Sciences, Kyushu University, Higashi ku, Fukuoka 812 8582, Japan
    Diabetologia 47:2145-51. 2004
    Several studies have reported that coffee has a protective effect against the development of type 2 diabetes. However, few of these studies used the standard glucose tolerance test to diagnose type 2 diabetes...
  36. ncbi Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States
    Constance E Ruhl
    Social and Scientific Systems Inc, 8758 Georgia Avenue, Silver Spring, MD 20910, USA
    Gastroenterology 128:24-32. 2005
    Based on experimental and epidemiologic studies, we investigated whether coffee and caffeine consumption reduced the risk of elevated alanine aminotransferase (ALT) activity in persons at high risk for liver injury in a national, ..
  37. doi Caffeine withdrawal and high-intensity endurance cycling performance
    Christopher Irwin
    School of Public Health, Griffith University, Gold Coast, Queensland, Australia
    J Sports Sci 29:509-15. 2011
    ..Twelve well-trained and familiarized male cyclists, who were caffeine consumers (from coffee and a range of other sources), were recruited for the study...
  38. pmc Coffee consumption and risk of cancers: a meta-analysis of cohort studies
    Xiaofeng Yu
    Department of Gastroenterology, Huadong Hospital, Fudan University, Shanghai 200040, PR China
    BMC Cancer 11:96. 2011
    b>Coffee consumption has been shown to be associated with cancer of various sites in epidemiological studies. However, there is no comprehensive overview of the substantial body of epidemiologic evidence.
  39. doi Tea and coffee consumption and cardiovascular morbidity and mortality
    J Margot de Koning Gans
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Arterioscler Thromb Vasc Biol 30:1665-71. 2010
    To examine the associations of coffee and tea consumption with risk of morbidity and mortality of stroke and coronary heart disease (CHD) and with all-cause mortality.
  40. pmc A prospective cohort study of coffee consumption and risk of endometrial cancer over a 26-year follow-up
    Youjin Je
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 20:2487-95. 2011
    b>Coffee has been reported to lower levels of estrogen and insulin, two hormones implicated in endometrial carcinogenesis, but prospective data on the relation between coffee consumption and risk of endometrial cancer are limited.
  41. pmc Maternal consumption of coffee during pregnancy and stillbirth and infant death in first year of life: prospective study
    Kirsten Wisborg
    Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
    BMJ 326:420. 2003
    To study the association between coffee consumption during pregnancy and the risk of stillbirth and infant death in the first year of life.
  42. doi Effects of tea and coffee on cardiovascular disease risk
    Siv K Bøhn
    School of Medicine and Pharmacology, The University of Western Australia M570, 35 Stirling Highway, Crawley, WA 6009, Australia
    Food Funct 3:575-91. 2012
    Tea and coffee have been associated with risk of cardiovascular disease (CVD), both positively and negatively...
  43. doi Coffee consumption and risk of endometrial cancer: findings from a large up-to-date meta-analysis
    Youjin Je
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 131:1700-10. 2012
    Several epidemiological studies have examined the association between coffee drinking and risk of endometrial cancer...
  44. doi Tea and coffee consumption and risk of oral cavity cancer: results of a large population-based case-control study, the ICARE study
    Loredana Radoï
    INSERM, Centre for Research in Epidemiology and Population Health CESP, U1018, Epidemiology of occupational and social determinants of health team, F 94807 Villejuif, France
    Cancer Epidemiol 37:284-9. 2013
    Results on the relationship between coffee and tea drinking and the risk of oral cavity cancer are contrasted...
  45. doi Coffee consumption and mortality due to all causes, cardiovascular disease, and cancer in Japanese women
    Kemmyo Sugiyama
    Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    J Nutr 140:1007-13. 2010
    b>Coffee contains various compounds that have recently been reported to exert beneficial health effects. However, the conclusion of its relation with mortality has not yet been reached...
  46. ncbi Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages
    Ting Shen
    School of Bioscience and Biotechnology, Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon 200 701, Republic of Korea
    Biol Pharm Bull 33:128-32. 2010
    b>Coffee is a popular beverage worldwide with various nutritional benefits...
  47. pmc Coffee consumption and prostate cancer risk and progression in the Health Professionals Follow-up Study
    Kathryn M Wilson
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 103:876-84. 2011
    b>Coffee contains many biologically active compounds, including caffeine and phenolic acids, that have potent antioxidant activity and can affect glucose metabolism and sex hormone levels...
  48. ncbi Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination survey
    Hyon K Choi
    Arthritis Research Centre of Canada, Vancouver General Hospital, University of British Columbia, Vancouver, Canada
    Arthritis Rheum 57:816-21. 2007
    b>Coffee is one of the most widely consumed beverages in the world and may affect serum uric acid levels and risk of gout via various mechanisms...
  49. pmc Coffee drinking and risk of endometrial cancer--a population-based cohort study
    Emilie Friberg
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Intstitutet, Stockholm, Sweden
    Int J Cancer 125:2413-7. 2009
    b>Coffee drinking has been reported to have beneficial effects on insulin resistance, which has been directly associated with endometrial cancer...
  50. ncbi Prospective study of coffee consumption and risk of Parkinson's disease
    K Sääksjärvi
    National Public Health Institute, Mannerheimintie 166, Helsinki, Finland
    Eur J Clin Nutr 62:908-15. 2008
    To examine the prediction of coffee consumption on the incidence of Parkinson's disease.
  51. pmc Relationship between caffeine intake and plasma sex hormone concentrations in premenopausal and postmenopausal women
    Joanne Kotsopoulos
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 115:2765-74. 2009
    ..Caffeine intake may decrease risk of breast and ovarian cancer, although the data are not entirely consistent. Whether or not caffeine affects cancer risk by altering sex hormone levels is currently unknown...
  52. ncbi Does postprandial coffee intake enhance gastric emptying?: a crossover study using continuous real time 13C breath test (BreathID system)
    Keiko Akimoto
    Gastroenterology Division, Yokohama City University School of Medicine, Yokohama, Japan
    Hepatogastroenterology 56:918-20. 2009
    b>Coffee is one of the most popular beverages worldwide, however, few studies have examined the effects of coffee on the gastrointestinal system...
  53. ncbi Coffee, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women
    Rob M van Dam
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Diabetes Care 29:398-403. 2006
    High habitual coffee consumption has been associated with a lower risk of type 2 diabetes, but data on lower levels of consumption and on different types of coffee are sparse.
  54. doi Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study
    Marjo H Eskelinen
    Department of Neurology, University of Kuopio, P O Kuopio, Finland
    J Alzheimers Dis 16:85-91. 2009
    ..However, the long-term impact of caffeine on cognition remains unclear. We aimed to study the association between coffee and/or tea consumption at midlife and dementia/Alzheimer's disease (AD) risk in late-life...
  55. ncbi The relationship between the consumption of meat, fat, and coffee and the risk of colon cancer: a prospective study in Japan
    Shino Oba
    Department of Prevention for Lifestyle Related Diseases, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
    Cancer Lett 244:260-7. 2006
    ..98, 95% CI: 1.24-3.16). In women, daily coffee drinkers had a reduced risk in comparison with individuals who never or rarely drank coffee (adjusted RR=0...
  56. ncbi Association of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenopausal Japanese women
    C Nagata
    Department of Public Health, Gifu University School of Medicine, Japan
    Nutr Cancer 30:21-4. 1998
    ..Its effect may be mediated by hormonal changes. The relationships between caffeine-containing beverages (coffee, green tea, black tea, oolong tea, and cola) and serum concentrations of estradiol and sex hormone-binding ..
  57. pmc Some like it hot: the influence and implications of climate change on coffee berry borer (Hypothenemus hampei) and coffee production in East Africa
    Juliana Jaramillo
    Institute of Plant Diseases and Plant Protection, University of Hannover, Hannover, Germany
    PLoS ONE 6:e24528. 2011
    The negative effects of climate change are already evident for many of the 25 million coffee farmers across the tropics and the 90 billion dollar (US) coffee industry...
  58. pmc Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene
    Casimiro Cárdenas
    Department of Molecular Biology and Biochemistry, Faculty of Sciences, University of Malaga, Malaga, Spain
    PLoS ONE 6:e23407. 2011
    Epidemiological studies have shown that unfiltered coffee consumption is associated with a low incidence of cancer...
  59. ncbi Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols
    Won Jun Lee
    Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA
    Carcinogenesis 27:269-77. 2006
    We studied the modulating effects of caffeic acid and chlorogenic acid (two common coffee polyphenols) on the in vitro methylation of synthetic DNA substrates and also on the methylation status of the promoter region of a representative ..
  60. doi Consumption of filtered and boiled coffee and the risk of incident cancer: a prospective cohort study
    Lena Maria Nilsson
    Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
    Cancer Causes Control 21:1533-44. 2010
    Despite potentially relevant chemical differences between filtered and boiled coffee, this study is the first to investigate consumption in relation to the risk of incident cancer.
  61. doi Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial
    Kerstin Kempf
    Institute of Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich, Heine University Düsseldorf, Dusseldorf, Germany
    Am J Clin Nutr 91:950-7. 2010
    b>Coffee consumption is associated with a decreased risk of type 2 diabetes. Suggested mechanisms underlying the association have included attenuation of subclinical inflammation and a reduction in oxidative stress.
  62. ncbi Coffee and fetal death: a cohort study with prospective data
    Bodil Hammer Bech
    Danish Epidemiology Science Centre, Department of Epidemiology and Social Medicine, Institute of Public Health, University of Aarhus, Aarhus, Denmark
    Am J Epidemiol 162:983-90. 2005
    The authors conducted a cohort study within the Danish National Birth Cohort to determine whether coffee consumption during pregnancy is associated with late fetal death (spontaneous abortion and stillbirth)...
  63. doi Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study
    Rachel Bakker
    Departments of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands
    Am J Clin Nutr 91:1691-8. 2010
    ..Caffeine is a widely used and accepted pharmacologically active substance. The effect of caffeine intake during pregnancy on fetal growth and development is still unclear...
  64. pmc Coffee, tea, and incident type 2 diabetes: the Singapore Chinese Health Study
    Andrew O Odegaard
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    Am J Clin Nutr 88:979-85. 2008
    Increasing coffee intake was inversely associated with risk of type 2 diabetes in populations of European descent; however, data from high-risk Asian populations are lacking as are data on tea intake in general.
  65. ncbi Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity
    C Cavin
    Food Safety Group, Nestle Research Center, PO Box 44, Vers chez les Blanc, CH 1000 Lausanne 26, Switzerland
    Food Chem Toxicol 40:1155-63. 2002
    Epidemiological studies have found an inverse association between coffee consumption and the risk of certain types of cancers such as colorectal cancers. Animal data support such a chemopreventive effect of coffee...
  66. ncbi Coffee, cirrhosis, and transaminase enzymes
    Arthur L Klatsky
    Division of Research, Department of Medicine, Kaiser Permanente Medical Care Program, Oakland, Calif 94611, USA
    Arch Intern Med 166:1190-5. 2006
    A minority of persons at risk develop liver cirrhosis, but knowledge of risk modulators is sparse. Several reports suggest that coffee drinking is associated with lower cirrhosis risk.
  67. ncbi Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine
    Kelly L Johnston
    Centre for Nutrition and Food Safety, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, United Kingdom
    Am J Clin Nutr 78:728-33. 2003
    ..Accumulating evidence suggests that certain dietary polyphenols have biological effects in the small intestine that alter the pattern of glucose uptake. Their effects, however, on glucose tolerance in humans are unknown...
  68. ncbi Habitual coffee but not green tea consumption is inversely associated with metabolic syndrome: an epidemiological study in a general Japanese population
    Asuka Hino
    Department of Internal Medicine, Division of Cardio vascular Medicine and Cardiovascular Research Institute, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Japan
    Diabetes Res Clin Pract 76:383-9. 2007
    In Japan, metabolic syndrome used to be rare, and the level of coffee consumption was low...
  69. doi Recent developments on polyphenol–protein interactions: effects on tea and coffee taste, antioxidant properties and the digestive system
    Prasun Bandyopadhyay
    Unilever R and D Bangalore, 64 Main Road, Whitefield, Bangalore 560066, India
    Food Funct 3:592-605. 2012
    Tea and coffee are widely consumed beverages across the world and they are rich sources of various polyphenols...
  70. doi Prospective study of coffee and tea consumption in relation to risk of type 2 diabetes mellitus among men and women: the Whitehall II study
    Mark Hamer
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Br J Nutr 100:1046-53. 2008
    At least fourteen cohort studies have documented an inverse association between coffee consumption and risk of type 2 diabetes...
  71. doi Limitations to photosynthesis in coffee leaves from different canopy positions
    Wagner L Araujo
    Departamento de Biologia Vegetal, Universidade Federal de Vicosa, 36570 000 Vicosa, Minas Gerais, Brazil
    Plant Physiol Biochem 46:884-90. 2008
    Limitations to photosynthesis were explored in leaves from four canopy positions of field-grown, unshaded coffee (Coffea arabica L.), a tropical tree species classified as shade-obligatory...
  72. doi Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression
    Ute Boettler
    Department of Food Chemistry and Toxicology, University of Vienna, Währinger Str 38, A 1090 Vienna, Austria
    J Nutr Biochem 22:426-40. 2011
    ..We investigated whether coffee extracts (CEs) of different proveniences and selected constituents have an impact on the Nrf2/ARE pathway in human ..
  73. ncbi Combined phenyl silane and immunoaffinity column cleanup with liquid chromatography for determination of ochratoxin A in roasted coffee: collaborative study
    A C Entwisle
    Leatherhead Food RA, Surrey, UK
    J AOAC Int 84:444-50. 2001
    ..The method was tested at 3 different levels of ochratoxin A in roasted coffee, which spanned the range of possible future European regulatory limits...
  74. doi Chlorogenic acids from green coffee extract are highly bioavailable in humans
    Adriana Farah
    Departamento de Bioquimica, Laboratorio de Bioquimica Nutricional e de Alimentos, Instituto de Quimica, Universidade Federal do Rio de Janeiro, Ilha do Fundao, RJ, Brazil
    J Nutr 138:2309-15. 2008
    ..Caffeoylquinic acids (CQA) and dicaffeoylquinic acids (diCQA) are the main CGA found in nature. Because green coffee is a major source of CGA, it has been used for production of nutraceuticals...
  75. pmc No association of coffee consumption with gastric ulcer, duodenal ulcer, reflux esophagitis, and non-erosive reflux disease: a cross-sectional study of 8,013 healthy subjects in Japan
    Takeshi Shimamoto
    Kameda Medical Center Makuhari, Chiba, Japan
    PLoS ONE 8:e65996. 2013
    Probably due to caffeine-induced gastric acid secretion, negative effects of coffee upon various upper-gastrointestinal diseases have been precariously accepted, despite the inadequate epidemiological evidence...
  76. doi Bioavailability of chlorogenic acids following acute ingestion of coffee by humans with an ileostomy
    Angelique Stalmach
    Plant Products and Human Nutrition Group, Graham Kerr Building, Faculty of Medicine, University of Glasgow, Glasgow G128QQ, UK
    Arch Biochem Biophys 501:98-105. 2010
    ..absorption and metabolism of 385 micromol chlorogenic acids following a single intake of 200 mL of instant coffee by human volunteers with an ileostomy was investigated...
  77. doi Coffee and risk of prostate cancer incidence and mortality in the Cancer of the Prostate in Sweden Study
    Kathryn M Wilson
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    Cancer Causes Control 24:1575-81. 2013
    b>Coffee intake has recently been associated with significantly lower risk of lethal and advanced prostate cancer in a US population.
  78. ncbi 7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties
    M Ogawa
    Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Nara 630-0101, Japan
    J Biol Chem 276:8213-8. 2001
    ..synthase and Arabidopsis hypothetical proteins, a particular DNA fragment was amplified from an mRNA population of coffee plants...
  79. doi Coffee prevents early events in tamoxifen-treated breast cancer patients and modulates hormone receptor status
    Maria Simonsson
    Department of Oncology, Clinical Sciences, Lund, Lund University, Barngatan 2B, 22185, Lund, Sweden
    Cancer Causes Control 24:929-40. 2013
    Whether coffee modulates response to endocrine therapy in breast cancer patients is currently unknown. The CYP1A2 and CYP2C8 enzymes contribute to tamoxifen and caffeine metabolism...
  80. doi Coffee consumption and risk of colorectal cancer
    S Bidel
    Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland
    Eur J Clin Nutr 64:917-23. 2010
    The possible association between coffee consumption and risk of colorectal cancer has been extensively studied in the many populations...
  81. pmc Tea and coffee intake in relation to risk of breast cancer in the Black Women's Health Study
    Deborah A Boggs
    Slone Epidemiology Center at Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Cancer Causes Control 21:1941-8. 2010
    Prospective studies of tea and coffee intake and breast cancer risk have yielded inconsistent results. None of these studies has reported separately on African-American women...
  82. doi Coffee and amyotrophic lateral sclerosis: a possible preventive role
    Ettore Beghi
    Laboratory of Neurological Disorders, Mario Negri Institute, Via G La Masa 19, 20156 Milano, Italy
    Am J Epidemiol 174:1002-8. 2011
    The relation between coffee intake and risk of amyotrophic lateral sclerosis (ALS) was investigated in 377 newly diagnosed ALS patients from 4 Italian population-based registries in the European ALS Consortium (EURALS Group) (2007-2010)...
  83. ncbi The value of bees to the coffee harvest
    David W Roubik
    Smithsonian Tropical Research Institute, 34002 0948, USA
    Nature 417:708. 2002
    ..These findings, together with world coffee-harvest statistics and results from field studies of organically shade-grown coffee, indicate that coffee plants ..
  84. pmc Smart drugs "as common as coffee": media hype about neuroenhancement
    Bradley J Partridge
    UQ Centre for Clinical Research, The University of Queensland, Herston, Queensland, Australia
    PLoS ONE 6:e28416. 2011
    ..In this study we explored how the newsprint media portrays neuroenhancement...
  85. doi Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis
    Marieke G M Braem
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
    Am J Clin Nutr 95:1172-81. 2012
    In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of coffee and tea consumption on the risk of epithelial ovarian cancer (EOC).
  86. pmc Relationship between coffee consumption and prevalence of metabolic syndrome among Japanese civil servants
    Hideo Matsuura
    Department of Public Health, Wakayama Medical University School of Medicine, Wakayama, Japan
    J Epidemiol 22:160-6. 2012
    Metabolic syndrome has become a major worldwide public health problem. We examined the relationship between coffee consumption and the prevalence of metabolic syndrome among Japanese civil servants.
  87. pmc Cloning and biochemical characterization of an endo-1,4-β-mannanase from the coffee berry borer Hypothenemus hampei
    Carolina Aguilera-Gálvez
    Disciplina de Mejoramiento Genético, Centro Nacional de Investigaciones de Café Cenicafé, Planalto, Km 4 vía antigua, Chinchiná Manizales, Colombia
    BMC Res Notes 6:333. 2013
    The study of coffee polysaccharides-degrading enzymes from the coffee berry borer Hypothenemus hampei, has become an important alternative in the identification for enzymatic inhibitors that can be used as an alternative control of this ..
  88. pmc Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption
    Patrick Sulem
    deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
    Hum Mol Genet 20:2071-7. 2011
    b>Coffee is the most commonly used stimulant and caffeine is its main psychoactive ingredient. The heritability of coffee consumption has been estimated at around 50%...
  89. doi Alcohol, coffee, fish, smoking and disease progression in multiple sclerosis
    M B D'hooghe
    National MS Center Melsbroek Center for Outcomes Research and Laboratory for Experimental Surgery, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels
    Eur J Neurol 19:616-24. 2012
    ..Certain lifestyle factors might influence disease activity in multiple sclerosis (MS)...
  90. doi Bladder cancer, GSTs, NAT1, NAT2, SULT1A1, XRCC1, XRCC3, XPD genetic polymorphisms and coffee consumption: a case-control study
    Loredana Covolo
    Department of Experimental and Applied Medicine, Institute of Hygiene, Epidemiology and Public Health, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Eur J Epidemiol 23:355-62. 2008
    ..the study was to investigate NAT1, NAT2, GSTM1, GSTT1, GSTP1, SULT1A1, XRCC1, XRCC3 and XPD genetic polymorphisms, coffee consumption and risk of bladder cancer (BC) through a hospital-based case-control study...
  91. ncbi Leuconostoc holzapfelii sp. nov., isolated from Ethiopian coffee fermentation and assessment of sequence analysis of housekeeping genes for delineation of Leuconostoc species
    Katrien De Bruyne
    Laboratory of Microbiology, Ghent University, Ledeganckstraat 35, B 9000 Ghent, Belgium
    Int J Syst Evol Microbiol 57:2952-9. 2007
    A Gram-positive, ovoid lactic acid bacterium, strain LMG 23990(T), was isolated from Ethiopian coffee fermentation...
  92. ncbi Coffee blunts mental stress-induced blood pressure increase in habitual but not in nonhabitual coffee drinkers
    Isabella Sudano
    Cardiovascular Center, Cardiology, University Hospital Zurich, Zurich, Switzerland
    Hypertension 46:521-6. 2005
    b>Coffee is widely consumed, especially during mental stress conditions. Cardiovascular impact of coffee remains debated because the underlying mechanisms of action are complex...
  93. pmc Caffeinated coffee, decaffeinated coffee and endometrial cancer risk: a prospective cohort study among US postmenopausal women
    Ayush Giri
    Division of Biostatistics and Epidemiology, Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA 01003 9304, USA
    Nutrients 3:937-50. 2011
    There is plausible biological evidence as well as epidemiologic evidence to suggest coffee consumption may lower endometrial cancer risk...
  94. doi Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: possible link between coffee consumption and diabetes mellitus
    Biao Cheng
    Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People s Republic of China
    J Agric Food Chem 59:13147-55. 2011
    Global epidemic studies have suggested that coffee consumption is reversely correlated with the incidence of type 2 diabetes mellitus (T2DM), a metabolic disease...
  95. ncbi Coffee and tea consumption and cancers of the bladder, colon and rectum
    C G Woolcott
    Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada
    Eur J Cancer Prev 11:137-45. 2002
    b>Coffee has been observed to be associated weakly or not at all with bladder cancer risk, inversely with colon cancer risk, and inconsistently with rectal cancer risk...
  96. ncbi Pesticide-handling practices in agriculture in Tanzania: observational data from 27 coffee and cotton farms
    A V Ngowi
    Tropical Pesticide Research Institute, Arusha, Tanzania
    Int J Occup Environ Health 7:326-32. 2001
    ..The study involved 23 coffee farms with 246 persons exposed to hazardous practices, and four cotton farms with 45 exposed...
  97. pmc Inverse correlation between coffee consumption and prevalence of metabolic syndrome: baseline survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima, Japan
    Hidenobu Takami
    Department of Preventive Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    J Epidemiol 23:12-20. 2013
    It is unclear whether consumption of coffee and green tea is associated with metabolic syndrome.
  98. pmc The metabolic and performance effects of caffeine compared to coffee during endurance exercise
    Adrian B Hodgson
    Human Performance Laboratory, School of Sport and Exercise Science, University of Birmingham, Birmingham, United Kingdom
    PLoS ONE 8:e59561. 2013
    ..However, whether caffeine ingested through coffee has the same effects is still subject to debate...
  99. doi Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice
    Lap Ho
    Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Nutr Neurosci 15:37-45. 2012
    There is accumulating evidence that coffee consumption may reduce risk for type 2 diabetes, a known risk factor for Alzheimer's and other neurological diseases...
  100. ncbi Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects
    Kazuya Kozuma
    Health Care Research Laboratories, Kao Corporation, Tokyo, Japan
    Hypertens Res 28:711-8. 2005
    A water-soluble green coffee bean extract (GCE) has been shown to be effective against hypertension in both spontaneously hypertensive rats and humans...
  101. doi Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial
    Mohammad Ali Raeessi
    Department of Otolaryngology, Baqiyatallah University of Medical Sciences, Tehran, Iran
    Prim Care Respir J 22:325-30. 2013
    ..Two of the suggested treatments for PPC are systemic steroid and honey plus coffee.

Research Grants63

  1. Analyzer for Monitoring Personal Environmental Exposure to Fluids and Materials
    MATTHEW CUSACK; Fiscal Year: 2010
    ..a subject/patient comes into contact, including: food stuffs, medicines, spices, condiments, liquids (water, wine, coffee beer, tea) and all materials placed on the subject/patient's skin such as: lotions, perfumes, cosmetics (..
  2. Hepatitis C Clinical Trial-Clinical Center
    Jules L Dienstag; Fiscal Year: 2009
    ..quantitative liver function tests, serum fibrosis markers, esophageal varices, dietary constituents including coffee and caffeine, health related quality of life and depressive symptoms;validation of fibrosis staging;and biomarkers ..
  3. Aromatic Amine-DNA Lesions: Mutagenicity and Repair
    Suse Broyde; Fiscal Year: 2013
    ..foods, notably meats, products of fuel combustion such as diesel exhaust, tobacco smoke, cooking oil fumes, coffee, tea and spices, and polluted air and water...
  4. 2011 Eukaryotic mRNA Processing Conference
    David J Stewart; Fiscal Year: 2011
    ..For the 2011 meeting we will subdivide each plenary session into two parts (separated by a coffee break) that focus on related but separate topics...
  5. RA-Related Autoantibodies in Healthy FDR of RA Patients
    Jill M Norris; Fiscal Year: 2011
    ..In addition, associations between exposures such as smoking, coffee, estrogens, pregnancy, infections, and environmental toxins such as silica and the presence of RA-related ..
  6. Pharmacogenomics of Parkinson's Disease
    Haydeh Payami; Fiscal Year: 2013
    ..3) testing human candidate genes and regulatory regions in pathways of interest for their effect on smoking- or coffee-associated PD risk reduction, (4) replication in independent studies...
  7. Tongue-pressure timing for liquid flow detection and control in swallowing
    CATRIONA MARGARET STEELE; Fiscal Year: 2012
    ..We drink water when we are thirsty, and swallow our morning coffee without a second thought...
  8. Genetic Modification of Triggers of Acute Myocardial Infarction
    ANA B BAYLIN; Fiscal Year: 2011
    ..It has been shown that heavy physical exertion and coffee intake are two triggers of acute myocardial infarction...
  9. Neural Models of Behavior
    Dana H Ballard; Fiscal Year: 2011
    ..PUBLIC HEALTH RELEVANCE: When we perform common everyday tasks, such as driving, making coffee or making a sandwich, we depend heavily on the ability to use our eyes...
  10. Food and Beverage Patterns that Predict Weight Gain Among Adolescents
    Alison E Field; Fiscal Year: 2013
    ..g., Gatorade), energy drinks (e.g., Red Bull), and prepared sweetened coffee beverages (e.g., Dunkin Donuts Coffee Coolattas(R)) among adolescents and young adults...
  11. Genetic Analysis of Onset Age of Parkinson's Disease
    Haydeh Payami; Fiscal Year: 2012
    ..of these genes with two environmental factors that are inversely associated with PD risk;namely, smoking and coffee. Identifying susceptibility genes will provide clues to the causes of PD and may suggest new strategies for ..
  12. Using the Default Effect to Promote Healthy Behavior
    Gretchen B Chapman; Fiscal Year: 2012
    ..The dietary choice study will examine coffee purchases in cafis that use different defaults for type of milk...
  13. Learning to Control Flexible Objects Using Error-Tolerant Movement Strategies
    CHRISTOPHER JAMES HASSON; Fiscal Year: 2012
    ..For example, coffee in a cup can only be controlled by manipulating the cup, and the coffee may spill if the movements are ..
  14. Advantages of HPLC with Ultra Stable Phases
    Peter W Carr; Fiscal Year: 2011
    ..x RPLC), the 14 low molecular weight components of native and mutant maize extracts, as well as urine, wine and 15 coffee samples, all using RPLC x RPLC...
  15. Estimating Effects of Interventions in Longitudinal Data
    Miguel Hernan; Fiscal Year: 2013
    ..individuals increase their activity to at least 30 minutes brisk walking per day," "everybody drinks 2 cups of coffee daily," and "statin therapy is initiated after a diagnosis of diabetes is made...
  16. CSHL 2013Eukaryotic mRNA Processing Conference
    David J Stewart; Fiscal Year: 2013
    ..Each plenary session will be subdivided into two parts (separated by a coffee break) that focus on related but separate topics...
  17. Synergistic Neuroprotective Mechanisms of Coffee Components in Parkinson's Diseas
    Jeffry B Stock; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Coffee is by far the most widely and highly consumed herbal extract. Numerous epidemiological studies indicate that coffee consumption affords reduced risk of Parkinson's disease (PD)...
  18. Social Network and Contextual Influences on Substance Use and HIV Risk Among YMSM
    IAN WALTER HOLLOWAY; Fiscal Year: 2012
    ..g. bars, clubs, coffee shops, bookstores) where YMSM in Los Angeles gather...
  19. 4th NIH Roadmap Meeting on Membrane Protein Structures and Complexes
    Robert M Stroud; Fiscal Year: 2012
    ..and provides conference facilities where talks and poster presentations, as well as breakfast, lunch and coffee breaks are in adjacent spaces to encourage discussion and conversation during breaks...
  20. ESTROGENS AND VITAMIN A ROLE IN DISEASE PREVENTION
    Annlia Paganini Hill; Fiscal Year: 1991
    ..2) Investigating the effects of dietary factors, elective drugs, smoking, coffee and alcohol consumption on risk of cancer (including bladder, breast, and colon cancers)...
  21. Risk Factors for Gout Among Women
    Hyon Choi; Fiscal Year: 2009
    ..of gout: 1) increased risk with sugar-sweetened soft drinks and fructose consumption;2) decreased risk with coffee intake;and 3) decreased risk with vitamin C consumption...
  22. Clinical and Scientific Advances in the Treatment of Poorly Healing Wounds
    Luisa A DiPietro; Fiscal Year: 2010
    ..Informal discussion among participants will be encouraged during coffee breaks and the utilization of a round table format at lunch...
  23. The 6th International Fission Yeast Meeting
    NICHOLAS R RHIND; Fiscal Year: 2011
    ..All meals will be served at the Simmons cafeteria, which can accommodate 600 at one sitting. Coffee breaks will be held at the conference center during the morning and evening session...
  24. Neuropharmacology of Cue-Induced Nicotine Relapse
    Xiu Liu; Fiscal Year: 2009
    ..g., finishing a meal, the consumption of alcoholic beverages, being with friends who smoke, drinking coffee, reading the morning newspaper) become cues that elicit subjective states that can trigger craving, drug-seeking ..
  25. Polysomnography in Homeopathic Remedy Effects
    Iris Bell; Fiscal Year: 2007
    ..All subjects also will report insomnia from drinking coffee (a symptom common in homeopathy to both remedy types) and will replace it with a non-coffee caffeinated beverage ..
  26. EPIDEMIOLOGIC AND BIOLOGIC PREDICTORS OF IVF SUCCESS
    Daniel Cramer; Fiscal Year: 2002
    ..present if the ART cycle involved direct injection of sperm in eggs which suggests that caffeine (or tannins in coffee or tea) could be affecting ART success (or natural fertility) by interfering with sperm-egg penetration...
  27. Symposium: AHA Council on Basic Cardiovascular Sciences
    MARK ALAN SUSSMAN; Fiscal Year: 2011
    ..Significant interaction time is provided, however, in the form of 3 breakfasts, 2 lunches, 1 dinner, 6 coffee breaks, and 3 poster sessions...
  28. Neural Mechanisms Underlying Hand Choice for Unimanual Action
    Richard Ivry; Fiscal Year: 2013
    ..This problem is encountered many times each day-- picking up a coffee cup, using the telephone, pointing to a landmark when giving directions -- and accomplished in a seemingly ..
  29. MERCURY AND REPRODUCTIVE HEALTH IN WOMEN DENTISTS
    David Savitz; Fiscal Year: 1992
    ..Some of the confounders an effect modifiers to be studies include; nitrous oxide, smoking, coffee, alcohol, reproductive history, age of the mother at pregnancy, other occupational exposures, and the occupation ..
  30. SIOP Boston 2010 Annual Congress
    Lisa R Diller; Fiscal Year: 2010
    ..of opportunities to informally interact including a welcome reception, a gala dinner, and daily breakfasts and coffee breaks which will serve as central gathering points...
  31. Synaptic Processing in the Olfactory System
    Jeffry S Isaacson; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Whether it be the aroma of our morning coffee or the scent of a lover, the sense of smell is a critical feature of our daily life...
  32. Symposium: AHA Council on Basic Cardiovascular Sciences
    Richard N Kitsis; Fiscal Year: 2010
    ..Significant "interaction time" is provided, however, in the form of 3 breakfasts, 2 lunches, 1 dinner, 6 coffee breaks, and 3 poster sessions...
  33. International Conference on Movement and Sensation
    DOUGLAS STUART; Fiscal Year: 2001
    ..There will be dedicated time to view posters as well as coffee breaks served in the poster area...
  34. STRUCTURE/FUNCTION OF X GALACTOSIDASE
    Alex Zhu; Fiscal Year: 2000
    Alpha-Galactosidase (alpha-GAL) purified from green coffee bean cleaves the terminal galactose residue from the surface of group B erythrocytes, thereby converting these cells serologically to group O cells...
  35. Novel Neuroprotection by Caffeine in Parkinson's Disease
    Michael Schwarzschild; Fiscal Year: 2005
    ..Adapted from Applicant's Abstract): Recent epidemiological studies have strongly linked the common consumption of coffee and other caffeinated beverages to a significantly reduced risk of developing Parkinson's disease (PD), raising ..
  36. 1991 TESTIS WORKSHOP
    Bernard Robaire; Fiscal Year: 1991
    ..The long coffee and lunch breaks will help promote further communication amongst the participants...
  37. POPULATION BASED STUDY OF LOWER URINARY TRACT TUMORS
    Loraine Marrett; Fiscal Year: 1980
    ..study of BT, data about smoking (active and passive), occupational exposures, artificial sweetener and coffee consumption, hair dye use, quality of drinking water, and skin exposures to a variety of medicinal, chemical, and ..
  38. ROTATING SHIFTWORK AND REPRODUCTIVE OUTCOMES
    Xiping Xu; Fiscal Year: 2000
    ..and passive smoking, indoor coal combustion, cooking oil fumes, indoor coal use, conditioner, consumption of tea, coffee, and alcohol, and diet. Height and weight will be measured by standard methods...
  39. PHYSIOLOGICAL RESPONSE TO INTERMITTENT HEAT EXPOSURES
    STEPHAN KONZ; Fiscal Year: 1980
    ..Each session will last 10.5 hours (pretest, heat, post-test sessions with time for subjects to have coffee and lunch breaks in controlled environments)...
  40. DIGITAL IMAGE ARCHIVE ON THE AMERICAN EUGENICS MOVEMENT
    DAVID MICKLOS; Fiscal Year: 2002
    ..materials; write essays, commentaries, and biographies for the online publication, as well as for a CD-ROM and "coffee table" book publication of the Archive; serve as "lecturers" in moderated online chat presentations and Ask the ..
  41. The effects of caffeine and caffeine withdrawal on mood, cognition, and fMRI.
    MERIDETH ADDICOTT; Fiscal Year: 2009
    Caffeine is a widely used neurostimulant that is found in many foods and beverages such as coffee, tea, soft drinks, and chocolate...
  42. CAFFEINE EFFECTS ON STRESS REACTIVITY
    James Lane; Fiscal Year: 2001
    ..This clinical intervention trial includes groups of habitual coffee drinkers who have blood pressures in the high normal or mild hypertensive range and those who are currently ..
  43. EPIDEMIOLOGY AND GENETICS OF PARKINSON'S DISEASE
    Walter Rocca; Fiscal Year: 2005
    ..Exposures will be accessed through direct telephone interview, and will include tobacco, coffee, and alcohol use; markers of novelty seeking behavior; and, for women, use of estrogen replacement therapy after ..
  44. CAFFEINE'S EFFECTS ON SMOKING AND NICOTINE WITHDRAWAL
    James Lane; Fiscal Year: 1993
    Cigarette smoking is commonly linked to the consumption of caffeinated beverages, especially coffee. Epidemiological studies suggest strong correlations between number of cigarettes smoked and quantity of coffee consumed daily...
  45. IMMUNOASSAYS FOR MUTAGENIC AND CARCINOGENIC ADDUCTS
    CYNTHIA SEVILLA; Fiscal Year: 1990
    ..Methyl glyoxal is also a natural product and is present in freshly roasted coffee. Acrolein is a major industrial starting material, and is present in cigarette smoke...
  46. Exploring the Neuroprotective Potential of Tobacco and Coffee in Fly Models of PD
    Leo Pallanck; Fiscal Year: 2009
    ..the incidence of PD have provided overwhelming data in support of a substantially reduced risk of PD among coffee and tobacco users...
  47. COFFEE GLACTOSIDASE CDNA CLONING FOR BLOOD PROCESSING
    JOHN IVY; Fiscal Year: 1991
    ..The applicnats propose to synthesize and clone the cDNA encoding the alpha-galactosidase found in green coffee beans for eventual production in microbial expression systems...
  48. CAFFEINE METABOLIC RATIOS SERVING EPIDEMIOLOGY
    Werner Kalow; Fiscal Year: 1990
    A cup of coffee, tea, or a cola drink contain enough caffeine to allow the analysis of caffeine metabolites in urine; different ratios of selected metabolites yield information on the activity of AHH (a liver enzyme known to activate many ..
  49. Molecular Epidemiology of Parkinson's Disease
    DEMETRIUS MICHAEL MARAGANORE; Fiscal Year: 2010
    ..We will also determine how these genes interact with environmental risk factors including pesticides, tobacco, coffee, and alcohol...
  50. Biological Basis of Personality & Individual Differences
    Turhan Canli; Fiscal Year: 2004
    ..Socials (coffee breaks and receptions) are informal opportunities to mingle before dinner on the first and second day of the ..
  51. NURSING ROLE IN THE ADVANCE DIRECTIVE DECISION
    ANN HURLEY; Fiscal Year: 1992
    ..and being participant observers when a consensus decision is likely to be discussed at change of shift report and coffee breaks...
  52. LIFE STRESSORS IN DUODENAL ULCER--TWO SUBPOPULATIONS
    Susan Levenstein; Fiscal Year: 1992
    ..certain personality structure and is mediated partially through anxiety-related abuse of alcohol, cigarettes, and coffee, and that ulcers arising from temporary stress may heal slowly but will have a good long-term prognosis...
  53. Diet, gene-diet interactions and risk of Parkinson's
    Honglei Chen; Fiscal Year: 2004
    ..prospectively examine among 162,408 US men and women associations of PD with dietary intakes, focusing on folate, coffee, dietary antioxidants, fat, alcohol, and dairy products...
  54. Neurodevelopmental Effects of Moderate Prenatal Caffeine Exposure
    DEBORAH SOELLNER; Fiscal Year: 2009
    ..The proposed studies will investigate the effects of low dose (equivalent to 2-3 cups of coffee per day) chronic prenatal exposure to caffeine on fetal neurodevelopment...
  55. PREVENTION AND ACCESS INTERVENTION FOR BOSNIAN FAMILIES
    Stevan Weine; Fiscal Year: 2000
    ..More specifically, this study will investigate a Coffee and... Group (CAG) which is a time-limited multi-family education and support group for Bosnian families...
  56. Function of The Bile Acid Receptor FXR
    David Moore; Fiscal Year: 2006
    ..We have also identified cafestol, a coffee oil and the most potent LDL cholesterol raising agent known, as a potential FXR agonist...