developed countries

Summary

Summary: Countries that have reached a level of economic achievement through an increase of production, per capita income and consumption, and utilization of natural and human resources.

Top Publications

  1. pmc When to initiate combined antiretroviral therapy to reduce mortality and AIDS-defining illness in HIV-infected persons in developed countries: an observational study
    Lauren E Cain
    Harvard School of Public Health, Boston, MA, USA
    Ann Intern Med 154:509-15. 2011
  2. ncbi Differences in prevalence, awareness, treatment and control of hypertension between developing and developed countries
    Marta Pereira
    Department of Hygiene and Epidemiology, Cardiovascular R and D Unit, Universityof Porto Medical School, Porto, Portugal
    J Hypertens 27:963-75. 2009
  3. ncbi A comparison of two commercially available anti-HEV IgG kits and a re-evaluation of anti-HEV IgG seroprevalence data in developed countries
    Richard Bendall
    Clinical Microbiology, Royal Cornwall Hospital Trust, Truro, United Kingdom
    J Med Virol 82:799-805. 2010
  4. ncbi The quality of informed consent: mapping the landscape. A review of empirical data from developing and developed countries
    Amulya Mandava
    Department of Bioethics, National Institutes of Health, Bethesda, MD 20892, USA
    J Med Ethics 38:356-65. 2012
  5. ncbi Hepatitis E: an emerging infection in developed countries
    Harry R Dalton
    Peninsula College of Medicine and Dentistry, Royal Cornwall Hospital Trust, Truro, UK
    Lancet Infect Dis 8:698-709. 2008
  6. ncbi Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality
    Arnold Mitnitski
    Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    J Am Geriatr Soc 53:2184-9. 2005
  7. ncbi Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review
    Ann Van den Bruel
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Lancet 375:834-45. 2010
  8. pmc Modeling preventative strategies against human papillomavirus-related disease in developed countries
    Karen Canfell
    Cancer Epidemiology Research Unit, Cancer Council NSW, Sydney, Australia
    Vaccine 30:F157-67. 2012
  9. ncbi Tobacco control policy in developed countries: yesterday, today, and tomorrow
    Kenneth E Warner
    Department of Health Management and Policy, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109 2029, USA
    Nicotine Tob Res 12:876-87. 2010
  10. ncbi Characterizing whole diets of young children from developed countries and the association between diet and health: a systematic review
    Lisa G Smithers
    Discipline of Public Health, University of Adelaide, Australia
    Nutr Rev 69:449-67. 2011

Detail Information

Publications329 found, 100 shown here

  1. pmc When to initiate combined antiretroviral therapy to reduce mortality and AIDS-defining illness in HIV-infected persons in developed countries: an observational study
    Lauren E Cain
    Harvard School of Public Health, Boston, MA, USA
    Ann Intern Med 154:509-15. 2011
    ..350 × 10(9) cells/L initiate combined antiretroviral therapy (cART), but the optimal CD4 cell count at which cART should be initiated remains a matter of debate...
  2. ncbi Differences in prevalence, awareness, treatment and control of hypertension between developing and developed countries
    Marta Pereira
    Department of Hygiene and Epidemiology, Cardiovascular R and D Unit, Universityof Porto Medical School, Porto, Portugal
    J Hypertens 27:963-75. 2009
    ..treatment and control of hypertension were compared between men and women, and between developing and developed countries, adjusting for age...
  3. ncbi A comparison of two commercially available anti-HEV IgG kits and a re-evaluation of anti-HEV IgG seroprevalence data in developed countries
    Richard Bendall
    Clinical Microbiology, Royal Cornwall Hospital Trust, Truro, United Kingdom
    J Med Virol 82:799-805. 2010
    In developed countries, the incidence of hepatitis E virus (HEV) infection and the resulting seroprevalence are uncertain. Published estimates of seroprevalnce in these populations range from 0...
  4. ncbi The quality of informed consent: mapping the landscape. A review of empirical data from developing and developed countries
    Amulya Mandava
    Department of Bioethics, National Institutes of Health, Bethesda, MD 20892, USA
    J Med Ethics 38:356-65. 2012
    ..that the quality of informed consent of clinical research participants in developing countries is worse than in developed countries. To evaluate this assumption, we reviewed the available data on the quality of consent in both settings.
  5. ncbi Hepatitis E: an emerging infection in developed countries
    Harry R Dalton
    Peninsula College of Medicine and Dentistry, Royal Cornwall Hospital Trust, Truro, UK
    Lancet Infect Dis 8:698-709. 2008
    ..However, there is now a growing body of evidence that challenges this notion. Autochthonous hepatitis E in developed countries is far more common than previously recognised, and might be more common than hepatitis A...
  6. ncbi Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality
    Arnold Mitnitski
    Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    J Am Geriatr Soc 53:2184-9. 2005
    ..To investigate the relationship between accumulated health-related problems (deficits), which define a frailty index in older adults, and mortality in population-based and clinical/institutional-based samples...
  7. ncbi Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review
    Ann Van den Bruel
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    Lancet 375:834-45. 2010
    Our aim was to identify which clinical features have value in confirming or excluding the possibility of serious infection in children presenting to ambulatory care settings in developed countries.
  8. pmc Modeling preventative strategies against human papillomavirus-related disease in developed countries
    Karen Canfell
    Cancer Epidemiology Research Unit, Cancer Council NSW, Sydney, Australia
    Vaccine 30:F157-67. 2012
    ..vaccination against human papillomavirus (HPV) in pre-adolescent females has been introduced in most developed countries, supported by modeled evaluations that have almost universally found vaccination of pre-adolescent females ..
  9. ncbi Tobacco control policy in developed countries: yesterday, today, and tomorrow
    Kenneth E Warner
    Department of Health Management and Policy, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109 2029, USA
    Nicotine Tob Res 12:876-87. 2010
    ..We ask, therefore, what developed nations can expect of these policies in the future and what novel policy measures may be needed to continue the assault on tobacco...
  10. ncbi Characterizing whole diets of young children from developed countries and the association between diet and health: a systematic review
    Lisa G Smithers
    Discipline of Public Health, University of Adelaide, Australia
    Nutr Rev 69:449-67. 2011
    ..Few studies have characterized the diets of children under 5 years of age and linked diet with health. Given the limited evidence, research establishing the predictive validity of whole-of-diet methods in childhood is needed...
  11. ncbi Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys
    Koen Demyttenaere
    JAMA 291:2581-90. 2004
    Little is known about the extent or severity of untreated mental disorders, especially in less-developed countries.
  12. ncbi Diarrhoea in children: an interface between developing and developed countries
    Nikhil Thapar
    Centre for Adult and Paediatric Gastroenterology, Institute of Cell and Molecular Science, Barts and The London, Queen Mary School of Medicine and Dentistry, University of London, London, UK
    Lancet 363:641-53. 2004
    ..These strategies include vaccines and, most importantly, policies to address persisting inequalities between the developed and developing worlds with respect to nutrition, sanitation, and access to safe drinking water...
  13. pmc Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment
    Orestis A Panagiotou
    Clinical Trials and Evidence Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, University Campus, Ioannina, Greece
    BMJ 346:f707. 2013
    To compare treatment effects from randomised trials conducted in more developed versus less developed countries.
  14. pmc Use of dietary indexes among children in developed countries
    Chrystalleni Lazarou
    Department of Nutrition Science Dietetics, Harokopio University, Athens, Greece
    Adv Nutr 2:295-303. 2011
    ..aspects of diet in relation to health outcomes and sociodemographic factors in childhood populations of developed countries. Eighty-four papers published from 1980 to mid-2010 including 90 unique dietary indexes were reviewed...
  15. ncbi Social capital, life expectancy and mortality: a cross-national examination
    Brendan Kennelly
    Department of Economics, The National University of Ireland, Galway, Ireland
    Soc Sci Med 56:2367-77. 2003
    ..The paper casts doubt upon the widely accepted hypothesis that social capital has a positive effect on health and illustrates the importance of testing this kind of hypothesis in an extended model...
  16. ncbi Global mammal conservation: what must we manage?
    Gerardo Ceballos
    Instituto de Ecologia, UNAM, Apdo Postal 70 275, Mexico D F 04510, Mexico
    Science 309:603-7. 2005
    ..Different approaches, from protection (or establishment) of reserves to countryside biogeographic enhancement of human-dominated landscapes, will be required to approach this minimal goal...
  17. ncbi Differential profiles and inhibitory effect on rotavirus vaccines of nonantibody components in breast milk from mothers in developing and developed countries
    Sung Sil Moon
    Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 32:863-70. 2013
    ..We extended our study to understand the specific contribution of those nonantibody components in breastmilk to the neutralizing activity against rotavirus vaccine we observed...
  18. pmc Child mortality estimation: a comparison of UN IGME and IHME estimates of levels and trends in under-five mortality rates and deaths
    Leontine Alkema
    Department of Statistics and Applied Probability and Saw Swee Hock School of Public Health, National University of Singapore, Singapore
    PLoS Med 9:e1001288. 2012
    ..To understand what caused the differences in estimates, we summarised differences in underlying data and modelling approaches used by the two groups, and analysed their effects...
  19. ncbi A summary of the Agency for Healthcare Research and Quality's evidence report on breastfeeding in developed countries
    Stanley Ip
    Institute for Clinical Research and Health Policy Studies, Tufts Medical Center Evidence based Practice Center, 800 Washington Street, Boston, MA 02111, USA
    Breastfeed Med 4:S17-30. 2009
    This article summarizes the Agency for Healthcare Research and Quality's evidence report on the effects of breastfeeding on term infant and maternal health outcomes in developed countries.
  20. ncbi Cancer prevention in the Asia Pacific region
    Keun Young Yoo
    Seoul National University College of Medicine, Seoul, Korea
    Asian Pac J Cancer Prev 11:839-44. 2010
    ..Moreover, countries with professionals and researchers with advanced cancer research, education, and training also need to contribute through international cooperation...
  21. ncbi Inflammatory bowel disease in the Asia-Pacific area: a comparison with developed countries and regional differences
    Vineet Ahuja
    Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India
    J Dig Dis 11:134-47. 2010
    ..There is a male predominance in Crohn's disease in the Asian population. The NOD2/CARD15 gene is not associated with CD in the Japanese, Korean, Chinese and Indian population...
  22. ncbi Biomedical publication--global profile and trend
    Mahbubur Rahman
    Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto 606 8507, Japan
    Public Health 117:274-80. 2003
    ..Pragmatic policies should be adopted by the World Bank, World Health Organization, other United Nations bodies, and respective governments to encourage biomedical research in the less-developed parts of the world...
  23. ncbi Trends in HIV incidence in homosexual men in developed countries
    Andrew E Grulich
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW 2010, Australia
    Sex Health 5:113-8. 2008
    To describe trends in HIV notifications and in other measures of HIV incidence in homosexual men in developed countries.
  24. ncbi Mortality of epilepsy in developed countries: a review
    Lars Forsgren
    Department of Neurology, Umea University Hospital, Sweden
    Epilepsia 46:18-27. 2005
    ..The most common direct seizure-related cause of death in adolescents and young adults is sudden unexpected death, which is 24 times more common than in the general population...
  25. ncbi A varied pattern of change of the sex differential in survival in the G7 countries
    Frank Trovato
    Department of Sociology and Population Research Laboratory, University of Alberta, Edmonton, Canada
    J Biosoc Sci 38:391-401. 2006
    ..These trends explain the divergent pattern of the sex difference in life expectation in Japan as compared with the other G7 nations...
  26. ncbi The economic burden of metastatic breast cancer: a systematic review of literature from developed countries
    Talia S Foster
    Health Economic Research and Quality of Life Evaluation Services HERQuLES, Abt Bio Pharma Solutions, Inc, Lexington, MA 02421, USA
    Cancer Treat Rev 37:405-15. 2011
    ..The objective of our study was to understand the economic impact of metastatic breast cancer (MBC) and its treatment, and to evaluate the designs of these studies...
  27. pmc Post-HAART outcomes in pediatric populations: comparison of resource-limited and developed countries
    Elizabeth Peacock-Villada
    University of Washington School of Medicine, Seattle, Washington 98195 6340, USA
    Pediatrics 127:e423-41. 2011
    No formal comparison has been made between the pediatric post-highly active antiretroviral therapy (HAART) outcomes of resource-limited and developed countries.
  28. pmc Growth performance of affluent Indian children is similar to that in developed countries
    Nita Bhandari
    Department of Paediatrics, Centre for Diarrhoeal Disease and Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Bull World Health Organ 80:189-95. 2002
    ..was conducted in order to determine whether an affluent population in south Delhi had a growth performance similar to that in developed countries and to identify socioeconomic factors that militated against optimal growth in this group.
  29. ncbi Environment: globalization of conservation: a view from the south
    J P Rodriguez
    Instituto Venezolano de Investigaciones Científicas and PROVITA, Caracas, Venezuela
    Science 317:755-6. 2007
  30. pmc Cost-effectiveness of screening for open angle glaucoma in developed countries
    Anja Tuulonen
    Department of Ophthalmology, University of Oulu and Tampere University Hospital, Finland
    Indian J Ophthalmol 59:S24-30. 2011
    As all developed countries are struggling with health care costs growing too large and too fast, the current performance and overburden of glaucoma services demand a reappraisal of current management strategies...
  31. ncbi Utilisation of dental auxiliaries--attitudinal review from six developed countries
    Anthony S Kravitz
    School of Dentistry, Cardiff University, Health Park
    Int Dent J 57:267-73. 2007
    To identify reasons for the development of dental auxiliaries across six developed countries and to explore attitudes towards them.
  32. pmc The impact of economic recession on maternal and infant mortality: lessons from history
    Tim Ensor
    Immpact, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK
    BMC Public Health 10:727. 2010
    ..The effect of the recent world recession on population health has featured heavily in recent international meetings. Maternal health is a particular concern given that many countries were already falling short of their MDG targets for 2015...
  33. ncbi The fragile environments of inexpensive CD4+ T-cell enumeration in the least developed countries: strategies for accessible support
    Christoph H Larsen
    SynaLinQ Consulting, Ho Chi Minh City, Vietnam
    Cytometry B Clin Cytom 74:S107-16. 2008
    ..These locally run networks may serve as "templates" for improved laboratory services in general, in collaboration with CD4 counting, haematology and infectious disease diagnostics...
  34. pmc Prescription drug use during pregnancy in developed countries: a systematic review
    Jamie R Daw
    Centre for Health Services and Policy Research, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada
    Pharmacoepidemiol Drug Saf 20:895-902. 2011
    ..To review the literature describing patterns of outpatient prescription drug use during pregnancy by therapeutic category, potential for fetal harm, and overall...
  35. pmc Multiple determinants, common vulnerabilities, and creative responses: addressing the AIDS pandemic in diverse populations globally
    Kenneth H Mayer
    The Fenway Institute, Fenway Health, Boston, MA 02215, USA
    J Acquir Immune Defic Syndr 60:S31-4. 2012
    ..This effective approach to HIV prevention, care, and treatment is illustrated through examples of community-based responses in Haiti, the United States, Africa, and other impoverished settings...
  36. pmc The HIV Epidemic: High-Income Countries
    Sten H Vermund
    Institute for Global Health and Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Cold Spring Harb Perspect Med 2:a007195. 2012
    ..Recent developments in phylodynamic approaches have made it possible to obtain estimates of sequence evolution rates and network parameters for epidemics...
  37. pmc Indoor fuel exposure and the lung in both developing and developed countries: an update
    Akshay Sood
    Department of Medicine, School of Medicine, Health Sciences Center, University of New Mexico, 1 University of New Mexico, MSC 10 5550, Albuquerque, NM 87131, USA
    Clin Chest Med 33:649-65. 2012
    ..Tobacco use further potentiates the development of respiratory disease among subjects exposed to solid fuel smoke. There is a need to perform additional interventional studies in this field...
  38. ncbi A systematic review and meta-analysis of micronutrient intakes during pregnancy in developed countries
    Michelle L Blumfield
    School of Health Sciences, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia
    Nutr Rev 71:118-32. 2013
    ..This review summarizes the micronutrient intakes of pregnant women from developed countries and compares them with relevant national recommendations...
  39. ncbi Modeling the effects of health on economic growth
    A Bhargava
    Department of Economics, University of Houston, Houston, TX 77204 5882, USA
    J Health Econ 20:423-40. 2001
    ..Lastly, we computed confidence intervals for the effect of ASR on growth rate and applied a test for parameter stability. The results showed positive effects of ASR on GDP growth rates in low-income countries...
  40. pmc Climate change and food security: health impacts in developed countries
    Iain R Lake
    School of Environmental Sciences, University of East Anglia, Norwich, United Kingdom
    Environ Health Perspect 120:1520-6. 2012
    Anthropogenic climate change will affect global food production, with uncertain consequences for human health in developed countries.
  41. pmc The contextual effects of social capital on health: a cross-national instrumental variable analysis
    Daniel Kim
    RAND Corporation, Santa Monica, CA, USA
    Soc Sci Med 73:1689-97. 2011
    ..Given the close linkages between self-rated health and all-cause mortality, the public health gains from raising social capital within and across countries may be large...
  42. pmc Developed-developing country partnerships: benefits to developed countries?
    Shamsuzzoha B Syed
    African Partnerships for Patient Safety, WHO Patient Safety, WHO Headquarters, Avenue Appia, 1211 Geneva 27, Switzerland
    Global Health 8:17. 2012
    ..of information pointed to developing country innovations that can potentially inform health systems in developed countries. This information spanned all six WHO health system components...
  43. pmc Why have total cholesterol levels declined in most developed countries?
    Simon Capewell
    University of Liverpool, Liverpool, United Kingdom
    BMC Public Health 11:641. 2011
    ..Our paper addresses three major public health issues: cholesterol, statins and policies to prevent cardiovascular disease...
  44. ncbi [Comparison of the trends and current status of obesity between Japan and other developed countries]
    Yoshitaka Murakami
    Department of Health Science, Shiga University of Medical Science
    Nihon Rinsho 67:245-52. 2009
    We compared the obesity status in Japan with those in other developed countries, such as the US, WHO European region, Australia, and Canada...
  45. pmc The mystery of hepatitis E seroprevalence in developed countries: is there subclinical infection due to hepatitis E virus?
    Mohamed T Shata
    Clin Infect Dis 47:1032-4. 2008
  46. ncbi Body mass index, abdominal adiposity and blood pressure: consistency of their association across developing and developed countries
    S Doll
    Institute for Social and Preventive Medicine, University of Lausanne, Switzerland
    Int J Obes Relat Metab Disord 26:48-57. 2002
    ..Obesity is increasing worldwide because developing countries are adopting Western high-fat foods and sedentary lifestyles. In parallel, in many of them, hypertension is rising more rapidly, particularly with age, than in Western countries...
  47. ncbi Cigarette diffusion and sex differences in smoking
    F C Pampel
    Population Program, University of Colorado, Boulder, CO 80309 0484, USA
    J Health Soc Behav 42:388-404. 2001
    ..Smoking of men and women becomes more similar in nations that have the longest history of cigarette use rather than the greatest gender equality...
  48. ncbi Flavonoid intake and disability-adjusted life years due to Alzheimer's and related dementias: a population-based study involving twenty-three developed countries
    Kristopher Beking
    Institute for Health Research and Education, Simon Fraser University, Burnaby, British Columbia, Canada
    Public Health Nutr 13:1403-9. 2010
    ..There is a lack of population studies, however, on correlations between flavonoid intake and dementia. The main objective of the present study was to analyse such a relationship at a large-scale population level...
  49. ncbi The etiology of maternal mortality in developed countries: a systematic review of literature
    A Cristina Rossi
    Department of Gynecology, Obstetrics and Neonatology, University of Bari, Via Celentano 42, 70121 Bari, Italy
    Arch Gynecol Obstet 285:1499-503. 2012
    To review the literature about MD in developed countries.
  50. ncbi [Prevalence of obesity in developed countries: current status and perspectives]
    J Aranceta Bartrina
    Unidad de Nutrición Comunitaria, Subárea Municipal de Salud Pública, Bilbao, Espana
    Nutr Hosp 17:34-41. 2002
    Obesity is one of the main public health problems in developed countries. It is considered to be a risk factor associated with the genesis or development of the major chronic diseases...
  51. ncbi A fall-off in cervical screening coverage of younger women in developed countries
    L Lancucki
    NHS Cancer Screening Programmes, Sheffield, UK
    J Med Screen 17:91-6. 2010
    To analyse cervical screening coverage data by age over time in a number of developed countries throughout the world, with specific emphasis on trends for younger women and on age differentials between younger and older women.
  52. ncbi Factors associated with suboptimal compliance to vaccinations in children in developed countries: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Curr Med Res Opin 24:1719-41. 2008
    ..The suboptimal compliance to vaccinations continues to be a major public health problem...
  53. ncbi Economic evaluation of human papillomavirus vaccination in developed countries
    Marc Brisson
    Departement de Medecine sociale et preventive, Universite Laval, Quebec, Que, Canada
    Public Health Genomics 12:343-51. 2009
    ..The demand for modeling has resulted in the publication of numerous mathematical models looking at the cost-effectiveness of HPV vaccination...
  54. pmc Economic analyses of rubella and rubella vaccines: a global review
    Alan R Hinman
    Task Force for Child Survival and Development, Decatur, GA 30030, USA
    Bull World Health Organ 80:264-70. 2002
    ..To investigate whether the incorporation of rubella vaccine into immunization programmes in developing countries is economically justified...
  55. ncbi Common concerns amid diverse systems: health care experiences in five countries
    Robert J Blendon
    Harvard School of Public Health, USA
    Health Aff (Millwood) 22:106-21. 2003
    ..The most crucial policy implication of these findings is that a focus on a small population of intensive health system users could have the potential to both control costs and improve care...
  56. pmc Global estimate of the incidence of clinical pneumonia among children under five years of age
    Igor Rudan
    Department of Medical Stastistics, Epidemiology and Medical Infomatics, School of Public Health Andrija Stampar, Zagreb, Croatia
    Bull World Health Organ 82:895-903. 2004
    ..In this paper we aim to estimate the worldwide incidence of clinical pneumonia in young children...
  57. ncbi Who uses sunbeds? A systematic literature review of risk groups in developed countries
    S Schneider
    Mannheim Institute of Public Health, Social and Preventive Medicine, Mannheim Medical Faculty, Heidelberg University, Heidelberg, Germany
    J Eur Acad Dermatol Venereol 24:639-48. 2010
    ..There is still a lack of information among users, particularly among young people regarding the safety of solariums...
  58. pmc Modeling cervical cancer prevention in developed countries
    Jane J Kim
    Program in Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA
    Vaccine 26:K76-86. 2008
    ..review on existing mathematical models that have been used to evaluate HPV vaccination in the context of developed countries with existing screening programs...
  59. ncbi Political and welfare state determinants of infant and child health indicators: an analysis of wealthy countries
    Haejoo Chung
    Department of Health Policy and Management, Johns Hopkins School of Public Health, USA
    Soc Sci Med 63:829-42. 2006
    ..Our investigation suggests that strong political will that advocates for more egalitarian welfare policies, including public medical services, is important in maintaining and improving the nation's health...
  60. pmc Hepatocellular carcinoma prevention: a worldwide emergence between the opulence of developed countries and the economic constraints of developing nations
    Francesca Lodato
    Dipartimento di Medicina Interna e Gastroenterologia, UO di Gastroenterologia, Via Massarenti 9, Bologna 40138, Italy
    World J Gastroenterol 12:7239-49. 2006
    ..screening of blood units, use of disposable sanitary tools, HBV vaccination) have been achieved in developed countries, but in the same areas, alcohol- and dysmetabolism-related HCCs are emerging problems which require ..
  61. ncbi Child maltreatment: variation in trends and policies in six developed countries
    Ruth Gilbert
    MRC Centre of Epidemiology for Child Health, UCL Institute of Child Health, London, UK
    Lancet 379:758-72. 2012
    We explored trends in six developed countries in three types of indicators of child maltreatment for children younger than 11 years, since the inception of modern child protection systems in the 1970s...
  62. ncbi Differences in teenage pregnancy rates among five developed countries: the roles of sexual activity and contraceptive use
    J E Darroch
    The Alan Guttmacher Institute, New York, USA
    Fam Plann Perspect 33:244-50, 281. 2001
    ..and sexually transmitted disease (STD) rates are much higher in the United States than in most other developed countries. METHODS: Government statistics or nationally representative survey data were supplemented with data ..
  63. ncbi Biomedical research productivity: factors across the countries
    Mahbubur Rahman
    Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, Japan
    Int J Technol Assess Health Care 19:249-52. 2003
    ..The objective of this study was to elicit the factors related to worldwide variation in biomedical research productivity...
  64. ncbi The role of atopic sensitization in flexural eczema: findings from the International Study of Asthma and Allergies in Childhood Phase Two
    Carsten Flohr
    Centre of Evidence Based Dermatology and the Centre for Population Sciences, Institute of Clinical Research, University of Nottingham, Nottingham, United Kingdom
    J Allergy Clin Immunol 121:141-147.e4. 2008
    ..The association between allergic sensitization and eczema has been debated for years...
  65. ncbi Asbestos and mesothelioma: worldwide trends
    Laurie Kazan-Allen
    International Ban Asbestos Secretariat, P O Box 93, Stanmore, Great Britain HA7 4GR, UK
    Lung Cancer 49:S3-8. 2005
    ..Towards the end of the 20th century, governments in many developed countries banned or seriously restricted the use of asbestos...
  66. pmc International collaboration, funding and association with burden of disease in randomized controlled trials in Africa
    George H Swingler
    Professor, School of Child and Adolescent Health, University of Cape Town, Red Cross Children s Hospital, Klipfontein Road, Rondebosch, 7700 South Africa
    Bull World Health Organ 83:511-7. 2005
    ..that is of specific importance to Africa than with conditions of more general global importance or with conditions important to developed countries. We also assessed whether the source of funding influenced a study's relevance to Africa.
  67. ncbi Inequality and mortality: long-run evidence from a panel of countries
    Andrew Leigh
    Social Policy Evaluation, Analysis and Research Centre, Research School of Social Sciences, Australian National University, Australia
    J Health Econ 26:1-24. 2007
    ..Nor do our data suggest that changes in the income share of the richest 10% affect homicide or suicide rates...
  68. ncbi Deaths rise in good economic times: evidence from the OECD
    Ulf G Gerdtham
    Health Economics Program, Department of Clinical Sciences, Lund University, Malmo University Hospital, SE 205 02 Malmo, Sweden
    Econ Hum Biol 4:298-316. 2006
    ..The findings are consistent with evidence provided by other recent research and cast doubt on the hypothesis that economic downturns have negative effects on physical health...
  69. ncbi Sharing the benefits of genetic resources: from biodiversity to human genetics
    Doris Schroeder
    Centre for Professional Ethics, University of Central Lancashire, Preston, United Kingdom
    Dev World Bioeth 6:135-43. 2006
    ....
  70. ncbi Wage inequality, the health system, and infant mortality in wealthy industrialized countries, 1970-1996
    James A Macinko
    Department of Health Administration and Planning, National School of Public Health Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
    Soc Sci Med 58:279-92. 2004
    ..Results suggest that improving aspects of the healthcare system may be one way to partially compensate for the negative effects of social inequalities on population health...
  71. ncbi Surveillance of transfusion-transmissible infections comparison of systems in five developed countries
    Sheila F O'Brien
    National Epidemiology and Surveillance, Canadian Blood Services, 1800 Alta Vista Drive, Ottawa, Ontario, Canada K1G 4J5
    Transfus Med Rev 26:38-57. 2012
    ..The precise nature of such activities varies by country because of the structure of the blood programs and surveillance systems, the strategic focus of the blood programs, and the epidemiology of disease in each country...
  72. ncbi Puerperal pyrexia: a review. Part I
    Dushyant Maharaj
    Department of Obstetrics and Gynecology, Wellington School of Medicine, University of Otago, Wellington, New Zealand
    Obstet Gynecol Surv 62:393-9. 2007
    ..the leading causes of preventable maternal morbidity and mortality not only in developing countries but in developed countries as well...
  73. ncbi A systematic review of risk factors for cerebral palsy in children born at term in developed countries
    Sarah McIntyre
    Paediatrics and Child Health, School of Medicine, University of Sydney, Sydney, Australia
    Dev Med Child Neurol 55:499-508. 2013
    ..The secondary aim was to ascertain if the potential for prevention of these risk factors has been adequately explored...
  74. pmc The contribution of primary care systems to health outcomes within Organization for Economic Cooperation and Development (OECD) countries, 1970-1998
    James Macinko
    Department of Health Administration and Planning, National School of Public Health Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
    Health Serv Res 38:831-65. 2003
    ..To assess the contribution of primary care systems to a variety of health outcomes in 18 wealthy Organization for Economic Cooperation and Development (OECD) countries over three decades...
  75. ncbi Declining sex differences in mortality from lung cancer in high-income nations
    Fred C Pampel
    Population Program, University of Colorado, Boulder, CO 80309 0484, USA
    Demography 40:45-65. 2003
    ..However, I found a strong and consistent relationship between the sex difference and the stage of diffusion of the use of cigarettes...
  76. pmc Control of tuberculosis in large cities in developed countries: an organizational problem
    Joan A Cayla
    Epidemiology Service, Public Health Agency of Barcelona, Spain
    BMC Med 9:127. 2011
    Tuberculosis (TB) is still a serious public health issue, even in large cities in developed countries. Control of this old disease is based on complicated programs that require completion of long treatments and contact tracing...
  77. ncbi Sampling methods used in developed countries for behavioural surveillance among men who have sex with men
    Dana Paquette
    National Centre in HIV Social Research, University of New South Wales, Webster Building, UNSW 2052, Sydney, Australia
    AIDS Behav 14:1252-64. 2010
    The aim of this review was to develop an overview of the sampling methods used in developed countries for behavioural surveillance among men who have sex with men...
  78. ncbi Assessing the economics of vaccination for Neisseria meningitidis in industrialized nations: a review and recommendations for further research
    Denis Getsios
    Caro Research Institute, Nova Scotia, Canada
    Int J Technol Assess Health Care 20:280-8. 2004
    ..To review the existing health economic literature on meningococcal disease vaccination...
  79. ncbi Spectrum of AIDS-defining illnesses in Australia, 1992 to 1998: influence of country/region of birth
    G J Dore
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Darlinghurst, Australia
    J Acquir Immune Defic Syndr 26:283-90. 2001
    ..To examine the influence of country/region of birth on spectrum of AIDS-defining illness...
  80. ncbi Immunization strategies for the control of serogroup C meningococcal disease in developed countries
    Philippe De Wals
    Laval University, and Quebec National Public Health Institute, Department of Social and Preventive Medicine, Pavillon de l Est, 2180 chemin Sainte Foy, Quebec G1K 7P4, Canada
    Expert Rev Vaccines 5:269-75. 2006
    In developed countries, the epidemiology of serogroup C meningococcal disease is characterized by unpredictable outbreaks and a bimodal distribution of cases, with the highest incidence rate among those below 1 year of age and a second ..
  81. ncbi Income and the incidence of oral cavity cancer: cross-national study
    David T Chen
    Department of Otorhinolaryngology, Tzu Chi General Hospital, Tzu Chi University, Hualien City, Taiwan
    J Otolaryngol Head Neck Surg 38:208-11. 2009
    ..To examine the relation between income and oral cancer incidence in countries at different stages of economic development...
  82. ncbi Clostridium difficile: a problem of concern in developed countries and still a mystery in Latin America
    I T Balassiano
    WHO Collaborating Center for Leptospirosis, Oswaldo Cruz Foundation, Pavilhão Rocha Lima, 302 Manguinhos, Rio de Janeiro 21040 360, Brazil
    J Med Microbiol 61:169-79. 2012
    ..difficile for the first time in the near future...
  83. ncbi Responsibilities for poverty-related ill health
    Thomas W Pogge
    Ethics Int Aff 16:71-9. 2002
  84. ncbi A challenge to the world's scientists
    Kofi Annan
    Science 299:1485. 2003
  85. ncbi Correlation or causation? Income inequality and infant mortality in fixed effects models in the period 1960-2008 in 34 OECD countries
    Mauricio Avendano
    London School of Economics and Political Science, LSE Health and Social Care, London, UK
    Soc Sci Med 75:754-60. 2012
    ..Findings highlight the need to examine the impact of more specific social policies on infant mortality...
  86. ncbi Rotavirus vaccine RIX4414 (Rotarix™): a pharmacoeconomic review of its use in the prevention of rotavirus gastroenteritis in developed countries
    Greg L Plosker
    Adis, a Wolters Kluwer Business, Auckland, New Zealand
    Pharmacoeconomics 29:439-54. 2011
    ..series in infants and has demonstrated protective efficacy against RVGE in clinical trials conducted in developed countries. In addition, various naturalistic studies have demonstrated 'real-world' effectiveness after the ..
  87. ncbi The opportunities and obstacles to collaboration between the developing and developed countries in the field of occupational health
    Jorma Rantanen
    Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FIN 00250 Helsinki, Finland
    Toxicology 198:63-74. 2004
    ..A convincing government OSH policy, and close cooperation between social partners and the government are also critical factors that guarantee sustainable OSH programs in a developing country over a long-term basis...
  88. pmc A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries
    Xiaohui Li
    Cornea Genetic Eye Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Hum Mol Genet 21:421-9. 2012
    ..6 × 10(-7) (unadjusted P= 1.2 × 10(-9)). These findings suggest SNP rs4954218, located near the RAB3GAP1 gene, previously reported to be associated with corneal malformation, is a potential susceptibility locus for keratoconus...
  89. pmc An uncommon cause of seizures in children living in developed countries: neurocysticercosis--a case report
    Irene Raffaldi
    Department of Pediatrics, Division of Infectious Diseases, University of Turin, Regina Margherita Children s Hospital, Piazza Polonia 94, 10126, Turin, Italy
    Ital J Pediatr 37:9. 2011
    ..This case accentuates the need to consider neurocysticercosis in a child presenting with non febrile seizures, mainly if he emigrated from an area of high prevalence or if he had long-term stay in endemic regions...
  90. ncbi Pregnancy health status of sub-Saharan refugee women who have resettled in developed countries: a review of the literature
    Mary Carolan
    School of Nursing and Midwifery, Victoria University, Melbourne, VIC 8001, Australia
    Midwifery 26:407-14. 2010
    ..to present the literature relating to health status and pregnancy complications among sub-Saharan African women...
  91. ncbi Vaccines for rotavirus gastroenteritis universally needed for infants
    H Fred Clark
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Ann 33:536-43. 2004
    ..and Rotateq likely are to be launched at prices beyond those affordable in the poorest and neediest less-developed countries. It is essential that there be vigorous pursuit of new technologies to manufacture these products at ..
  92. ncbi Macro determinants of cause-specific injury mortality in the OECD countries: an exploration of the importance of GDP and unemployment
    Sana Muazzam
    Injury Control Research Center, West Virginia University, PO Box 9151, Morgantown, WV 26506, USA
    J Community Health 36:574-82. 2011
    ..GDP is more related to cause-specific injury mortality than unemployment. Injury mortality does not relate similarly to each diagnosis-specific cause among males and females. Further research on causation with more predictors is needed...
  93. ncbi Tissue engineering research in developing countries, the significant and differences as compared to the developed countries
    B S Aminuddin
    Tissue Engineering Center, UKM Medical Centre
    Med J Malaysia 63:47-8. 2008
    ..The discussion here is mainly on the evolution of tissue engineering in Malaysia and taking a model of tissue engineering in otolaryngology...
  94. pmc Occupational cancer in developed countries
    Aaron Blair
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Environ Health 10:S9. 2011
    ..our understanding about occupational cancer has been obtained from studies largely composed of white men in developed countries. The movement of industry from developed to developing countries underscores the need for future ..
  95. ncbi Incidence of dementia and Alzheimer disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana
    H C Hendrie
    Department of Psychiatry, Indiana University School of Medicine, 541 Clinical Dr, Room 394A, Indianapolis, IN 46202, USA
    JAMA 285:739-47. 2001
    ..If populations were identified with significantly lower or higher incidence rates of AD, the search for risk factors in the genesis of AD could be greatly enhanced...
  96. ncbi Zinc for infectious diarrhea in developed countries: should we be sprinkling our own lawns?
    John K Crane
    J Pediatr Gastroenterol Nutr 46:484-5. 2008
  97. ncbi Rotavirus vaccines in developed countries
    Jim P Buttery
    NHMRC Centre of Clinical Research Excellence in Child and Adolescent Immunisation, Murdoch Children s Research Institute, Infectious Diseases Unit, Royal Children s Hospital, Parkville, Australia
    Curr Opin Infect Dis 20:253-8. 2007
    ..The recent licensure in many nations of vaccines against rotavirus offers promise to significantly reduce this toll. The present review describes recent developments regarding rotavirus vaccines and the challenges they face...
  98. pmc Cigarette characteristic and emission variations across high-, middle- and low-income countries
    R J O'Connor
    Department of Health Behavior, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Public Health 124:667-74. 2010
    ..This study used standard smoking machine tests to examine the extent to which the industry is introducing engineering features that reduce tar and nicotine to cigarettes sold in middle- and low-income countries...
  99. ncbi Demographic effects of the introduction of steroid contraception in developed countries
    Henri Leridon
    INSERM, U569, F 94276 Le Kremlin Bicetre, INED, F 75020 Paris France
    Hum Reprod Update 12:603-16. 2006
    The use of the contraceptive pill increased very rapidly in the 1970s in many developed countries, and fertility almost simultaneously started to decline. We discuss here the possibility of a causal link between these two major changes...
  100. ncbi Comparing health system performance in OECD countries. Organization for Economic Cooperation and Development
    G Anderson
    Johns Hopkins School of Hygiene and Public Health, Department of Health Policy and Management, Baltimore, Maryland, USA
    Health Aff (Millwood) 20:219-32. 2001
    ..We also compare the performance of the United States with the other industrialized countries for selected indicators in 1960, 1980, and 1998. On most indicators the U.S. relative performance declined since 1960; on none did it improve...
  101. ncbi Losses of expected lifetime in the United States and other developed countries: methods and empirical analyses
    Vladimir M Shkolnikov
    Max Planck Institute for Demographic Research, Rostock, Germany
    Demography 48:211-39. 2011
    ..The latter can be related to weaknesses of health system and other factors resulting in premature death from heart diseases, amenable causes, accidents and violence...

Research Grants73

  1. Air Pollution on Adiposity and Vascular Dysfunction: White or Brown Matters?
    Qinghua Sun; Fiscal Year: 2013
    ..provided by applicant): Owing to the increase in obesity, life expectancy may start to decrease in developed countries for the first time...
  2. Regulation of epithelial cell homeostasis by actin microfilaments
    Seema Khurana; Fiscal Year: 2010
    ..affecting about 1 person in every 500 in USA), the colon carcinoma (the second most frequent malignancy in developed countries) and numerous infectious diseases...
  3. Mechanisms of Sex Determination in Zebrafish
    JOHN HARVEY POSTLETHWAIT; Fiscal Year: 2013
    ..disease, including testicular dysgenesis syndrome and polycystic ovary syndrome increasingly observed in developed countries. PUBLIC HEALTH RELEVANCE: Understanding the biological mechanisms that tip the balance of sex determination ..
  4. A quantitative proteomics approach to understand viral immune evasion strategies
    Michele E Hardy; Fiscal Year: 2010
    ..These viruses are responsible for significant morbidity in developed countries with an estimated 2...
  5. Molecular Mechanism of Protein Kinase Cbeta-Mediated Cholesterol Homeostasis
    Kamal D Mehta; Fiscal Year: 2010
    ..The greatest potential for arresting this epidemic is likely to come through a clearer understanding of its molecular pathogenesis to develop rational and mechanism based therapy. ..
  6. Role of Retroelements in Environmental Atherogenesis
    Kenneth S Ramos; Fiscal Year: 2010
    ..Studies are proposed in this application to study the role of virus-like sequences in the onset and progression of environmentally-induced atherosclerosis in experimental systems. ..
  7. Air Pollution on Adiposity and Vascular Dysfunction: White or Brown Matters?
    Qinghua Sun; Fiscal Year: 2010
    Owing to the increase in obesity, life expectancy may start to decrease in developed countries for the first time. Environmental factors are increasingly found to be associated with the development of obesity...
  8. The effect of trichloroethylene exposure on adverse pregnancy outcomes
    Iman Hassan; Fiscal Year: 2013
    ..Results from this project will provide new knowledge about potential mechanisms by which environmental toxicants may contribute to adverse birth outcomes. ..
  9. Heat Shock Protein Synthesis Inhibitor Treatment of Hepatitis C Viral Infection
    SAMUEL WHEELER FRENCH; Fiscal Year: 2013
    ..infection has a worldwide prevalence of 3% and is the main entity responsible for liver transplantation in developed countries for treatment of cirrhosis...
  10. Dietary Risk for Colon Cancer in the Mouse
    Leonard H Augenlicht; Fiscal Year: 2013
    ..provided by applicant): "Sporadic" colon cancer refers to >90% of colon cancer in the US and other developed countries. We have shown that this can be modeled by feeding C57Bl/6 mice a "new western- style diet" (NWD1) that ..
  11. Membrane Ion-channels in Helminth Parasites: Anthelmintic Resistance and Sites of
    RICHARD JOHN MARTIN; Fiscal Year: 2011
    ..5 billion people world- wide;these diseases are not a focus of interest in developed countries and part of a group of diseases known as the neglected tropical diseases...
  12. Analysis of the functions of axon guidance genes during vector mosquito developme
    MOLLY DUMAN SCHEEL; Fiscal Year: 2012
    ..have resurged in developing countries and are also emerging as clear threats for epidemic outbreaks in developed countries. Numerous factors contribute to the current inability to prevent or control these diseases, including poor ..
  13. CHEMOSENSORY PERCEPTION AND PSYCHOPHYSICS IN THE AGED
    CLAIRE L MURPHY; Fiscal Year: 2013
    ..disease, triples risk of diabetes, and impacts cognitive function, affects one in four adults in most developed countries (Poirier et al., 2006)...
  14. Epidemiological Research on Autism in Jamaica
    Mohammad H Rahbar; Fiscal Year: 2010
    ..The prevalence of ASD appears to be on the rise in developed countries, and has become a serious public health concern...
  15. Experimental COPD: remediation, mitigation
    DONALD JOHN MASSARO; Fiscal Year: 2010
    ..There is not treatment that slows the relentless progression of the disease or that reverses it. In this application, we use an animal model to investigate methods to slow progression and reverse the disease. ..
  16. Role of the insulin/IGF-axis in incident CIN-2+
    Howard D Strickler; Fiscal Year: 2010
    ..in Costa Rican women, using data from the subcohort (since there is sparse insulin/IGF-axis data outside of developed countries)...
  17. Abdominal Symptom Phenotypes: Pathways to New Biomarkers
    Robert Shulman; Fiscal Year: 2010
    ..New biomarkers (video capsule endoscopy, lymphocyte activation/cytokine diffuse noxious inhibitory control testing) will be used with newly recruited IBS and control subjects. ..
  18. Adjunctive Use of Apyrase to Fibrinolytic Therapy
    Ridong Chen; Fiscal Year: 2013
    ....
  19. Role of Lipoproteins in Chagasic heart disease
    JYOTHI FALGUNI NAGAJYOTHI; Fiscal Year: 2013
    ..Mortality due to cardiovascular disease is increasing in the most developed countries of South and Central America with the change to a high fat "western" diet...
  20. Molecular Analysis of GnRH Action
    Mark S Roberson; Fiscal Year: 2012
    ..Alternatively, a significant number of couples in the US and other developed countries confront issues of infertility...
  21. Vaccines for Sustainable Therapy of Opiate Addiction
    Frank M Orson; Fiscal Year: 2012
    ....
  22. Defining the telomerase holoenzyme in progenitor cells with aging
    Steven E Artandi; Fiscal Year: 2013
    ..An improved understanding of telomerase is crucial for designing therapies that will delay or reverse certain aspects of aging. ..
  23. Tb-FISH (Fluorescent in Situ Hybridization) Assay for Direct Detection of M. tube
    JYOTSNA S SHAH; Fiscal Year: 2010
    ..Based on the feasibility study performed in Phase I, we would like get a FDA approval for the TB-FISH assay. Therefore, in Phase II we shall perform all the studies required by FDA for a PMA filing. ..
  24. Molecular Imaging Probes for Reporting on Vascular Oxidative Response
    Alexei A Bogdanov; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Cardiovascular disease is the major cause of mortality in developed countries claiming 870,000 deaths/year in US alone (year 2004 statistics)...
  25. Angiogenic factors, abnormal placentation and adverse pregnancy outcomes
    Sarosh Rana; Fiscal Year: 2013
    ..The combined expertise of mentors and collaborators provide a unique opportunity for the applicant to achieve the goals of this project and to start a career as an independent investigator. ..
  26. Lab-on-a-chip for Neonatal Hyperbilirubinemia Screening
    Vijay Srinivasan; Fiscal Year: 2012
    ..The paradigm of centralized newborn screening that works well in developed countries is quite challenging to implement in highly populated developing countries such as India or China...
  27. Endothelial SK3 Channel Modulation of EDHF is Estrogen Regulated
    Mike T Lin; Fiscal Year: 2011
    ..factor that can further lead to cardiovascular morbidity and mortality, the number one cause of death in developed countries. Understanding endothelial SK3 channel function, expression, distribution, and regulation may reveal novel ..
  28. Neurobiological mechanisms of nicotine reinforcement: Role of the nucleus tractus
    LUIS MIGUEL TUESTA; Fiscal Year: 2012
    ..Results from the experiments outlined in this proposal will increase our basic understanding of nicotine addiction, and may provide exciting targets for the development of novel therapeutics for smoking cessation. ..
  29. Plasmalogen-derived bioactive lipids in atherosclerosis
    David A Ford; Fiscal Year: 2013
    ..In this proposal we will test the hypothesis that novel chlorinated lipid species are important mediators of atherosclerosis. ..
  30. Gut microflora: Impact on neonatal immunity, viral gastroenteritis and vaccines
    ANASTASIA NICKOLAEVNA VLASOVA; Fiscal Year: 2013
    ..Current attenuated human RV (AttHRV) oral vaccines are effective in infants in developed countries, but for unexplained reasons, they lack efficacy in impoverished countries where diarrhea mortality is ..
  31. Role of HSV Induced RNA Degradation in Pathogenesis
    David A Leib; Fiscal Year: 2013
    ..Summary/Abstract Herpes simplex virus (HSV) keratitis is a leading cause of non-traumatic blindness in developed countries, with more than 400,000 cases in the USA, with approximately 50,000 new and recurring cases per year...
  32. Targeting Bacterial Virulence Transcription Factors, a Novel Antibiotic Approach
    George A Garcia; Fiscal Year: 2011
    ..to be a disease of the "third world", like many other highly contagious diseases it is rapidly spreading to developed countries. The emergence of drug and multi-drug resistant strains of Shigella emphasize the need for novel antibiotic ..
  33. Genetic hearing screening for newborns
    Xi Lin; Fiscal Year: 2009
    ..More than half of congenital hearing loss cases in developed countries are caused by genetic mutations...
  34. INVESTIGATION OF THE ROLES OF NUCLEAR RECEPTOR FXR IN HEPATOCELLULAR
    Wendong Huang; Fiscal Year: 2013
    ..HCC remains a major cause of cancer death worldwide, and the incidence of HCC in developed countries, including the United States, is increasing...
  35. SCABIES: BIOLOGY, CULTURE, HOST SPECIFICITY AND ANTIGENS
    Larry G Arlian; Fiscal Year: 2013
    ..In developed countries, the disease shows no socioeconomic preference and affects 1-10% of the general population while it more ..
  36. Training in Environmental Health to Reduce Chronic Disease in Latin America
    Philip J Landrigan; Fiscal Year: 2013
    ..factors including indoor allergens, air pollution and tobacco smoke;2) obesity and diabetes are epidemic in developed countries and are increasing alarmingly in the developing world...
  37. Studies of YlxM of Streptococcus mutans, a newly identified component of the Sign
    MATTHEW LAWRENCE WILLIAMS; Fiscal Year: 2013
    ..Additionally this research represents the basis of a doctoral dissertation project. Hence, this fellowship application will assist in trainin a student with an interest in oral health research to become an independent investigator. ..
  38. Alteration of ER:mitochondrial contacts by human cytomegalovirus infection
    ANAMARIS MARTHA COLBERG POLEY; Fiscal Year: 2010
    ..HCMV is the leading viral cause of congenital disorders in developed countries and a significant contributor of morbidity and mortality in immunosuppressed patients...
  39. Early Environmental Hygiene and Pediatric Asthma
    Christine C Johnson; Fiscal Year: 2009
    The prevalence of asthma has increased over the 20th century in most, if not all, developed countries of the world...
  40. Structure-Function Studies of the Proton-Gated Urea Channel from H. Pylori
    Hartmut Luecke; Fiscal Year: 2013
    ..Without active intervention, at least 20% of the population of developed countries will continue to be infected by this gastric pathogen...
  41. Occupational exposure to manganese and noise potentiate hearing loss
    Richard J Salvi; Fiscal Year: 2013
    ..In the US and other developed countries, manganism is primarily an occupational disorder most often seen in the welding profession because welding ..
  42. Impact of maternal hyperleptinemia on health: CNS mechanisms
    Rebecca Leshan; Fiscal Year: 2013
    ..Our proposed research will examine the mechanisms by which offspring brains may be metabolically "programmed", with the ultimate goal of identifying new targets for the prevention and treatment of obesity. ..
  43. BIOLOGY OF TRABECULAR RESPONSE TO LASER TRABECULOPLASTY
    Ted S Acott; Fiscal Year: 2012
    ..These studies are focused at understanding the molecular nature of the aqueous humor outflow pathway, which is normally responsible for avoiding glaucoma and which becomes obstructed to produce glaucoma. ..
  44. Cell-synthesized Thread-based Tissue Engineering
    NICOLAS L'HEUREUX; Fiscal Year: 2012
    ....
  45. Role of the MC3-R in Obesity and Metabolic Syndrome
    Roger D Cone; Fiscal Year: 2012
    ..This application seeks to identify the sites and mechanisms of action of the MC3-R in this phenomenon, so as to better understand the etiology, and eventually discover better treatments for metabolic syndrome. ..
  46. Improving the efficacy of anti-nicotine immunotherapy
    Alexey G Mukhin; Fiscal Year: 2010
    ..smoking, is a chronic relapsing disorder that constitutes one of the leading preventable causes of death in developed countries. In the United States, where approximately 47 million adults are current cigarette smokers, smoking-..
  47. T cell immunity to influenza virus in the aged nasal mucosa
    Bas Baaten; Fiscal Year: 2013
    ..events in the aged NALT after infection could lead to the identification of strategies for improvement of vaccines to respiratory viruses for the elderly, which are the fastest growing segment of the population in developed countries.
  48. Physiological reactivity to acute stress during pregnancy
    LISA MICHELLE CHRISTIAN; Fiscal Year: 2010
    ..In the U.S., the preterm birth rate is 12-13% as compared to 5-9% in other developed countries. Persistent racial disparities contribute to this discrepancy...
  49. Vascular Function, Cognition, and Brain MRI in Atherosclerotic Vascular Disease
    David J Moser; Fiscal Year: 2012
    ..abstract_text> ..
  50. IMAGING AUTOIMMUNE DISEASE
    Diane J Mathis; Fiscal Year: 2013
    ..diseases, type-1 diabetes (T1D) being a classic example, currently afflict around 7% of the population of developed countries. While much progress has been made in deciphering disease mechanisms, many critical issues remain ..
  51. FATTY ACID TRANSPORT IN EUKARYOTES
    CONCETTA CHRISTINE DIRUSSO; Fiscal Year: 2010
    ..these diseases are the leading causes of morbidity and mortality in the United States and most other developed countries. Specific metabolic disturbances in lipid metabolism result in elevating the levels of circulating free ..
  52. Function and Secretion of Bordetella Filamentous Hemagglutinin
    Peggy A Cotter; Fiscal Year: 2013
    ..Despite high vaccine coverage, incidence has been increasing in several developed countries since the 1990s, due apparently to waning immunity in adolescents and young adults who were vaccinated, ..
  53. PPAR-Gamma's Role in Aberrant Adipogenesis and Fibrosis in Systemic Sclerosis
    BENJAMIN DOUGLAS KORMAN; Fiscal Year: 2013
    ..This work will help me to develop the knowledge and skills necessary to become an independent investigator and ultimately a future leader in rheumatology and the field of SSc research. ..
  54. Bioprocess for cardiac cell generation from human induced pluripotent stem cells
    EMMANOUHL TZANAKAKIS; Fiscal Year: 2013
    ..applicant): Myocardial infarction is a major cause of morbidity and mortality in the United States and most developed countries. Heart transplantation is an effective therapeutic modality in reconstituting the function of damaged heart...
  55. Telomere dysfunction, chromosome 9 instability and bladder cancer risk
    Yun Ling Zheng; Fiscal Year: 2013
    ..Bladder cancer is the fourth most common malignancy in men from developed countries, whereas it is the most common malignancy in men in the Middle East and sub-Saharan Africa...
  56. Functional analysis of AMD-associated HTRA1 promoter polymorphism
    Noriko Esumi; Fiscal Year: 2010
    ..AMD is the leading cause of irreversible blindness among elderly people in the developed countries and an etiologically complex disease caused by multiple genetic and environmental factors...
  57. PTEN Gene Therapy for Vein Graft Disease
    Christopher D Kontos; Fiscal Year: 2010
    ..S. and other developed countries. Autologous saphenous veins are the most commonly used conduits for bypass grafting in both coronary and ..
  58. FETAL AND NEONATAL NEUROBEHAVIOR AND PRENATAL ANTIDEPRESSANT EXPOSURE: THE CHILD
    Amy L Salisbury; Fiscal Year: 2013
    ..It is the third leading cause of disease burden in developed countries and is associated with shorter gestation, child sleep problems (shortened sleep cycles, frequent awakening),..
  59. The Role of the Proteasome in Troponin related Cardiomyopathies
    ALDRIN VERNO GOMES; Fiscal Year: 2013
    ..in diagnosis and treatment of heart diseases, cardiomyopathies remain the most prevalent cause of death in developed countries. Mutations in cardiac troponin T (cTnT) are responsible for ~7% of all familial hypertrophic cardiomyopathy ..
  60. Novel Approaches in Treatment of Vascular Injury Following Balloon Angioplasty
    YEVGENIYA EMRE KOSHMAN; Fiscal Year: 2013
    ..infarction, stroke, and peripheral vascular disease, accounting for nearly half of all mortality in developed countries. Percutaneous transluminal angioplasty has become a well-established technique for revascularization of ..
  61. Periodontal Pathogens-induced Atherosclerosis in ApoE-/- and Integrin Beta6-/- mi
    IRINA MARIE VELSKO; Fiscal Year: 2013
    ..provided by applicant): Atherosclerotic vascular disease (ASVD) is the leading cause of death in developed countries. Although there are numerous recognized risk factors for ASVD, including hypertension, hyperlipidemia, ..
  62. Non-canonical VEGF receptor signaling regulates retinal neovascularization
    MICHAEL EDWIN BOULTON; Fiscal Year: 2012
    ..Understanding this novel non-canonical VEGF signalling pathway(s) will provide new information on angiogenesis and allow development of a sustainable treatment strategy for AMD and diabetic retinopathy. ..
  63. DIETARY & GENETIC CONTROL OF ROS DAMAGE TO THE LENS
    Norman S Wolf; Fiscal Year: 2010
    ..These will aid in the search for initiating events and the mechanisms leading up to the cataract formation. ..
  64. MULTIDISCIPLINARY ENVIRONMENTAL HEALTH TRAINING
    David Carpenter; Fiscal Year: 2006
    ..will not lose our valuable relationships that have been established over the past six years in these more developed countries. The six countries in this application have very severe environmental health issues, and lack the resources,..
  65. Towards Understanding the Morbidity of HEV Infection
    Mohamed Tarek Shata; Fiscal Year: 2007
    ..E (HEV) is enterically transmitted RNA virus that causes acute viral hepatitis (AVH) in many lesser developed countries (LDC), with frequent reports of fulminant hepatitis in pregnant women...
  66. Artificial Cornea Using New Biomaterials
    MAX MAGINNESS; Fiscal Year: 2009
    ..In developed countries increasing numbers of LASIK procedures are rendering many potential donor eyes unusable...
  67. Integrated Multifunctional Imaging of Deep Vein Thrombosis
    Walter Scott; Fiscal Year: 2009
    ..clinical problem, representing the leading cause of preventable in-hospital mortality in the USA and other developed countries. Indeed, anywhere from 60,000 to 200,000 people are dying each year in the United States because of DVT ..
  68. Pilot study of Newborn screening for hemoglobinopathies in South Gujarat India
    Lakshmanan Krishnamurti; Fiscal Year: 2009
    ..other genetic and metabolic diseases has primarily been implemented in highly structured health systems in developed countries. In India, SCD is most prevalent in indigenous populations classified as scheduled tribes who have a high ..
  69. Completely Digitizing the Custom-Fit Hearing Aid Shell Manufacturing Process
    STEVEN YI; Fiscal Year: 2010
    ..disturbing, of the 300 million people in the world who need hearing aids, less than 20 percent of people in developed countries and less than 1 percent of the rest actually have hearing aids...
  70. Novel Combretastatin A4 analogs for Treatment of Retinal Neovascularization
    Danyang Chen; Fiscal Year: 2007
    ..Diabetic retinopathy (DR) is a common complication of diabetes mellitus and a leading cause of blindness in developed countries. Abnormal angiogenesis in the retina or retinal neovascularization (NV) is one of the major pathological ..
  71. Immunomodulatory Mechanisms of Sublingual Immunotherapy
    Louis Rosenthal; Fiscal Year: 2006
    ..To investigate this controversial therapy, these studies will use a novel rat model to compare the efficacy of high vs. low doses of allergen drops and to elucidate mechanisms of sublingual immunotherapy. ..
  72. Botswana Research Ethics Network: A Cross-National Approach to Ethics Review
    Jon F Merz; Fiscal Year: 2010
    ..S. and other developed countries can facilitate a collaborative approach to training and improving the capacity and quality of local review, ..
  73. CALICIVIRAL INFECTIONS AND DISEASE IN SOUTHERN INDIA
    MARY ESTES; Fiscal Year: 2009
    ..Recent studies in developed countries have shown there is an unprecedented degree of genetic diversity in human calicivirus isolates, ..