cost benefit analysis


Summary: A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.

Top Publications

  1. ncbi Good research practices for cost-effectiveness analysis alongside clinical trials: the ISPOR RCT-CEA Task Force report
    Scott Ramsey
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Value Health 8:521-33. 2005
  2. ncbi Cost-effectiveness acceptability curves--facts, fallacies and frequently asked questions
    Elisabeth Fenwick
    Centre for Evaluation of Medicines, St Joseph s Hospital, Hamilton, Canada
    Health Econ 13:405-15. 2004
  3. ncbi Analysis of cost data in randomized trials: an application of the non-parametric bootstrap
    J A Barber
    MRC Clinical Trials Unit, 222 Euston Road, London NW1 2DA, UK
    Stat Med 19:3219-36. 2000
  4. ncbi A guide to cost-effectiveness acceptability curves
    Elisabeth Fenwick
    Br J Psychiatry 187:106-8. 2005
  5. ncbi Principles of good practice for decision analytic modeling in health-care evaluation: report of the ISPOR Task Force on Good Research Practices--Modeling Studies
    Milton C Weinstein
    Center for Risk Analysis, Harvard School of Public Health, Boston, MA 02115, USA
    Value Health 6:9-17. 2003
  6. ncbi Probabilistic sensitivity analysis for NICE technology assessment: not an optional extra
    Karl Claxton
    Centre for Health Economics, Department of Economics and Related Studies, University of York, UK
    Health Econ 14:339-47. 2005
  7. ncbi The irrelevance of inference: a decision-making approach to the stochastic evaluation of health care technologies
    K Claxton
    Commonwealth Fund of New York, Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, MA, USA
    J Health Econ 18:341-64. 1999
  8. pmc Economic evaluation of human papillomavirus vaccination in the United Kingdom
    Mark Jit
    Modelling and Economics Unit, Centre for Infections, Health Protection Agency, London NW9 6BT
    BMJ 337:a769. 2008
  9. ncbi The death of cost-minimization analysis?
    A H Briggs
    Health Economics Research Centre, University of Oxford, UK
    Health Econ 10:179-84. 2001
  10. ncbi Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy
    Gillian D Sanders
    Duke Clinical Research Institute, Duke University, Durham, NC 27715, USA
    N Engl J Med 352:570-85. 2005

Detail Information

Publications372 found, 100 shown here

  1. ncbi Good research practices for cost-effectiveness analysis alongside clinical trials: the ISPOR RCT-CEA Task Force report
    Scott Ramsey
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Value Health 8:521-33. 2005
    ..Its goal was to develop a guidance document for designing, conducting, and reporting cost-effectiveness analyses conducted as a part of clinical trials...
  2. ncbi Cost-effectiveness acceptability curves--facts, fallacies and frequently asked questions
    Elisabeth Fenwick
    Centre for Evaluation of Medicines, St Joseph s Hospital, Hamilton, Canada
    Health Econ 13:405-15. 2004
    ..The aim of the paper is to serve as a reference tool to accompany the increased use of CEACs within major medical journals...
  3. ncbi Analysis of cost data in randomized trials: an application of the non-parametric bootstrap
    J A Barber
    MRC Clinical Trials Unit, 222 Euston Road, London NW1 2DA, UK
    Stat Med 19:3219-36. 2000
  4. ncbi A guide to cost-effectiveness acceptability curves
    Elisabeth Fenwick
    Br J Psychiatry 187:106-8. 2005
    ..This includes several studies in the mental health field. This editorial uses examples from recent papers to illustrate how cost-effectiveness acceptability curves are constructed, what they represent and how they should be interpreted...
  5. ncbi Principles of good practice for decision analytic modeling in health-care evaluation: report of the ISPOR Task Force on Good Research Practices--Modeling Studies
    Milton C Weinstein
    Center for Risk Analysis, Harvard School of Public Health, Boston, MA 02115, USA
    Value Health 6:9-17. 2003
    ..This report describes the consensus of a task force convened to provide modelers with guidelines for conducting and reporting modeling studies...
  6. ncbi Probabilistic sensitivity analysis for NICE technology assessment: not an optional extra
    Karl Claxton
    Centre for Health Economics, Department of Economics and Related Studies, University of York, UK
    Health Econ 14:339-47. 2005
    ..Finally, some of the methodological challenges posed by the need fully to characterise decision uncertainty and to inform the research agenda will be identified and discussed...
  7. ncbi The irrelevance of inference: a decision-making approach to the stochastic evaluation of health care technologies
    K Claxton
    Commonwealth Fund of New York, Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, MA, USA
    J Health Econ 18:341-64. 1999
    ..It also ensures that the type of information acquired is driven by the objectives of the health care system, is consistent with the budget constraint on service provision and that research is designed efficiently...
  8. pmc Economic evaluation of human papillomavirus vaccination in the United Kingdom
    Mark Jit
    Modelling and Economics Unit, Centre for Infections, Health Protection Agency, London NW9 6BT
    BMJ 337:a769. 2008
    ..To assess the cost effectiveness of routine vaccination of 12 year old schoolgirls against human papillomavirus infection in the United Kingdom...
  9. ncbi The death of cost-minimization analysis?
    A H Briggs
    Health Economics Research Centre, University of Oxford, UK
    Health Econ 10:179-84. 2001
    ..The first shows a situation where analysts might be tempted (inappropriately) to employ CMA rather than CEA. The second illustrates one of the rare circumstances in which CMA may be justified as a legitimate form of analysis...
  10. ncbi Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy
    Gillian D Sanders
    Duke Clinical Research Institute, Duke University, Durham, NC 27715, USA
    N Engl J Med 352:570-85. 2005
    ..The costs, benefits, and cost-effectiveness of screening for human immunodeficiency virus (HIV) in health care settings during the era of highly active antiretroviral therapy (HAART) have not been determined...
  11. ncbi The lifetime cost of current human immunodeficiency virus care in the United States
    Bruce R Schackman
    Department of Public Health, Weill Medical College of Cornell University, New York, New York 10021, USA
    Med Care 44:990-7. 2006
    ..We sought to project the lifetime cost of medical care for human immunodefiency virus (HIV)-infected adults using current antiretroviral therapy (ART) standards...
  12. ncbi Does NICE have a cost-effectiveness threshold and what other factors influence its decisions? A binary choice analysis
    Nancy Devlin
    City Health Economics Centre, Department of Economics, City University, UK
    Health Econ 13:437-52. 2004
    ..The results suggest a threshold somewhat higher than NICEs stated 'range of acceptable cost effectiveness' of pound 20,000-30,000 British pounds per QALY--although the exact meaning of a 'range' in this context remains unclear...
  13. ncbi Cost-effectiveness of computerised cognitive-behavioural therapy for anxiety and depression in primary care: randomised controlled trial
    Paul McCrone
    Centre for the Economics of Mental Health, Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 185:55-62. 2004
    ..Cognitive-behavioural therapy (CBT) is effective for treating anxiety and depression in primary care, but there is a shortage of therapists. Computer-delivered treatment may be a viable alternative...
  14. pmc Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis
    Clare L Gillies
    Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester LE1 7RH
    BMJ 336:1180-5. 2008
  15. ncbi The cost diary: a method to measure direct and indirect costs in cost-effectiveness research
    M E Goossens
    Institute for Rehabilitation Research, Hoensbroek, The Netherlands
    J Clin Epidemiol 53:688-95. 2000
    ..However, for physiotherapy contacts there were differences between the self-reported and insurance data. This study shows how the cost diary might be used successfully in cost-effectiveness studies...
  16. ncbi Screening for type 2 diabetes mellitus: a cost-effectiveness analysis
    Thomas J Hoerger
    RTI International, Research Triangle Park, North Carolina 27709, USA
    Ann Intern Med 140:689-99. 2004
    ..No randomized, controlled trial of screening for diabetes has been conducted. In the absence of direct evidence, cost-effectiveness models may provide guidance about preferred screening strategies...
  17. ncbi Expanded screening for HIV in the United States--an analysis of cost-effectiveness
    A David Paltiel
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, Conn 06520 8034, USA
    N Engl J Med 352:586-95. 2005
    ..The effect of expanded screening for HIV is unknown in the era of effective antiretroviral therapy...
  18. pmc Cost effectiveness of an outpatient multidisciplinary pulmonary rehabilitation programme
    T L Griffiths
    Section of Respiratory Medicine, Department of Medicine, University of Wales College of Medicine, Llandough Hospital, Penarth, Vale of Glamorgan CF64 2XX, UK
    Thorax 56:779-84. 2001
    ..We undertook a cost/utility analysis in conjunction with a randomised controlled clinical trial of pulmonary rehabilitation versus standard care...
  19. ncbi Handling uncertainty in cost-effectiveness models
    A H Briggs
    Health Economics Research Centre, University of Oxford, England
    Pharmacoeconomics 17:479-500. 2000
    ..Such probabilistic analyses are related to parameter uncertainty. In addition, modelling uncertainty is likely to add a further layer of uncertainty to the results of particular analyses...
  20. pmc Global variation in terrestrial conservation costs, conservation benefits, and unmet conservation needs
    Andrew Balmford
    Conservation Biology Group, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, United Kingdom
    Proc Natl Acad Sci U S A 100:1046-50. 2003
    ..Substantially increased investment in tropical conservation is therefore urgently required if opportunities for cost-effective action are not to be missed...
  21. pmc Health and economic implications of HPV vaccination in the United States
    Jane J Kim
    Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 359:821-32. 2008
    ..The cost-effectiveness of prophylactic vaccination against human papillomavirus types 16 (HPV-16) and 18 (HPV-18) is an important consideration for guidelines for immunization in the United States...
  22. ncbi Expanded HIV screening in the United States: effect on clinical outcomes, HIV transmission, and costs
    A David Paltiel
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, Connecticut 06520 8034, USA
    Ann Intern Med 145:797-806. 2006
    ..An extensive literature supports expanded HIV screening in the United States. However, the question of whom to test and how frequently remains controversial...
  23. ncbi Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy
    Sean R Tunis
    Office of Clinical Standards and Quality, Centers for Medicare and Medicaid Services, Baltimore, MD 21244, USA
    JAMA 290:1624-32. 2003
    ..For these changes to occur, clinical and health policy decision makers will need to become more involved in all aspects of clinical research, including priority setting, infrastructure development, and funding...
  24. ncbi Projected cost-effectiveness of statewide universal newborn hearing screening
    Ron Keren
    Department of Medicine, Children s Hospital, Boston, Massachusetts, USA
    Pediatrics 110:855-64. 2002
  25. ncbi The quality of reporting in published cost-utility analyses, 1976-1997
    P J Neumann
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Ann Intern Med 132:964-72. 2000
    ..We examined quality of reporting by journal type and number of cost-utility analyses a journal has published...
  26. pmc Cost and cost-effectiveness of nationwide school-based helminth control in Uganda: intra-country variation and effects of scaling-up
    Simon Brooker
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Health Policy Plan 23:24-35. 2008
    ..70-9.51). Independent variables were shown to be statistically associated with both sets of estimates. This study highlights the potential bias in transferring data across settings without understanding the nature of observed variations...
  27. ncbi Thinking outside the box: recent advances in the analysis and presentation of uncertainty in cost-effectiveness studies
    Andrew H Briggs
    Health Economics Research Centre, Department of Public Health, University of Oxford, Oxford OX3 7LF, United Kingdom
    Annu Rev Public Health 23:377-401. 2002
    ..Finally, we outline some of the challenges for future research in this area-particularly in relation to the appropriate use of Bayesian methods and methods for analyzing costs that are typically skewed and often incomplete...
  28. ncbi Male circumcision for HIV prevention in sub-Saharan Africa: who, what and when?
    Richard G White
    London School of Hygiene and Tropical Medicine, London, UK
    AIDS 22:1841-50. 2008
    ..We explore how the population-level impact of circumcision varies by target age group, coverage, time-to-scale-up, level of risk compensation and circumcision of HIV infected men...
  29. ncbi What is the price of life and why doesn't it increase at the rate of inflation?
    Peter A Ubel
    University of Michigan Health Systems 300 N Ingalls, Room 7C27 Ann Arbor, MI 48109 0429, USA
    Arch Intern Med 163:1637-41. 2003
  30. pmc Cost effectiveness analysis of strategies for maternal and neonatal health in developing countries
    Taghreed Adam
    Health Systems Financing, Evidence and Information for Policy, World Health Organization, Switzerland
    BMJ 331:1107. 2005
    ..To determine the costs and benefits of interventions for maternal and newborn health to assess the appropriateness of current strategies and guide future plans to attain the millennium development goals...
  31. pmc Cost-effectiveness analysis of insecticide-treated net distribution as part of the Togo Integrated Child Health Campaign
    Dirk H Mueller
    Health Economics and Financing Programme, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Malar J 7:73. 2008
    ..To evaluate the cost-effectiveness of the first nationwide delivery of long-lasting insecticide-treated nets (LLITNs) as part of the 2004 measles vaccination campaign in Togo to all children between nine months and five years...
  32. pmc Bias in published cost effectiveness studies: systematic review
    Chaim M Bell
    St Michael s Hospital, Toronto, Ontario, Canada M5B 1W8
    BMJ 332:699-703. 2006
  33. pmc Cost effectiveness analysis of strategies for tuberculosis control in developing countries
    Rob Baltussen
    Institute for Medical Technology Assessment iMTA, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, Netherlands
    BMJ 331:1364. 2005
    ..To assess the costs and health effects of tuberculosis control interventions in Africa and South East Asia in the context of the millennium development goals...
  34. ncbi Development of an economic model to assess the cost effectiveness of treatment interventions for chronic obstructive pulmonary disease
    Michael Spencer
    Global Health Outcomes, GlaxoSmithKline Research and Development, Greenford, Middlesex, UK
    Pharmacoeconomics 23:619-37. 2005
  35. ncbi When is it cost-effective to change the behavior of health professionals?
    J Mason
    Centre for Health Services Research, University of Newcastle upon Tyne, Newcastle upon Tyne, England
    JAMA 286:2988-92. 2001
  36. ncbi Estimating mean QALYs in trial-based cost-effectiveness analysis: the importance of controlling for baseline utility
    Andrea Manca
    Centre for Health Economics, University of York, UK
    Health Econ 14:487-96. 2005
  37. ncbi Increasing the generalizability of economic evaluations: recommendations for the design, analysis, and reporting of studies
    Michael Drummond
    University of York, North Yorkshire, UK
    Int J Technol Assess Health Care 21:165-71. 2005
    ..However, the sharing of the results from HTAs raises questions about their generalizability; namely, are the results of an HTA undertaken in one country relevant to another?..
  38. ncbi Accounting for the cost of scaling-up health interventions
    Benjamin Johns
    Global Programme on Evidence for Health Policy GPE EQC, World Health Organization, CH 1211 Geneva 27, Switzerland
    Health Econ 13:1117-24. 2004
    ..Results show changing marginal costs as predicted by economic theory...
  39. pmc Analysis and interpretation of cost data in randomised controlled trials: review of published studies
    J A Barber
    Department of Medical Statistics and Evaluation, Imperial College School of Medicine, London W12 0NN
    BMJ 317:1195-200. 1998
    ..To review critically the statistical methods used for health economic evaluations in randomised controlled trials where an estimate of cost is available for each patient in the study...
  40. ncbi A Bayesian approach to stochastic cost-effectiveness analysis
    A H Briggs
    Health Economics Research Centre, University of Oxford, Headington, UK
    Health Econ 8:257-61. 1999
    ..Although it is argued that their interpretation as the probability that an intervention is cost-effective given the data requires a Bayesian interpretation, this should generate no misgivings for the frequentist...
  41. ncbi Effects of task-oriented circuit class training on walking competency after stroke: a systematic review
    Lotte Wevers
    Center of Excellence for Rehabilitation Medicine Utrecht, Rehabilitation Center De Hoogstraat, Utrecht, The Netherlands
    Stroke 40:2450-9. 2009
    ..Our aim was to systematically review randomized, controlled trials of task-oriented circuit class training on gait and gait-related activities in patients with stroke...
  42. ncbi Projecting the cost-effectiveness of adherence interventions in persons with human immunodeficiency virus infection
    Sue J Goldie
    Center for Risk Analysis, Harvard School of Public Health, Boston, Massachusetts 02115 5924, USA
    Am J Med 115:632-41. 2003
    ..To explore the cost-effectiveness of interventions to improve adherence to combination antiretroviral therapy in patients with human immunodeficiency virus (HIV) infection...
  43. ncbi OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence
    W Zhang
    University of Edinburgh, Osteoarticular Research Group, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom
    Osteoarthritis Cartilage 15:981-1000. 2007
  44. pmc Conserving biodiversity efficiently: what to do, where, and when
    Kerrie A Wilson
    The Ecology Centre, School of Integrative Biology, University of Queensland, St Lucia, Queensland, Australia
    PLoS Biol 5:e223. 2007
    ..Applying this new framework will ensure investment in actions that provide the most cost-effective outcomes for biodiversity conservation. This will help to minimise the misallocation of scarce conservation resources...
  45. ncbi Mathematical programming for the efficient allocation of health care resources
    A A Stinnett
    Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA
    J Health Econ 15:641-53. 1996
    ..Methods are also presented for incorporating ethical constraints into the resource allocation process, including explicit identification of the cost of equity...
  46. ncbi Systematic review of isolation policies in the hospital management of methicillin-resistant Staphylococcus aureus: a review of the literature with epidemiological and economic modelling
    B S Cooper
    Academic Department of Geriatric Medicine, Royal Free Campus, Royal Free and University College Medical School, University of London, London, UK
    Health Technol Assess 7:1-194. 2003
    ..To develop transmission models to study the effectiveness and cost-effectiveness of isolation policies in controlling MRSA...
  47. pmc Benefit-cost analysis of addiction treatment: methodological guidelines and empirical application using the DATCAP and ASI
    Michael T French
    Department of Economics, Pompeu Fabra University, Barcelona, Spain
    Health Serv Res 37:433-55. 2002
    ..To provide detailed methodological guidelines for using the Drug Abuse Treatment Cost Analysis Program (DATCAP) and Addiction Severity Index (ASI) in a benefit-cost analysis of addiction treatment...
  48. ncbi The relative contribution of outcome domains in the total economic benefit of addiction interventions: a review of first findings
    Kathryn E McCollister
    Health Services Research Center and Department of Epidemiology and Public Health D93, University of Miami, Miami, FL 33136, USA
    Addiction 98:1647-59. 2003
    ..This paper provides a focused summary of the relative contribution of addiction intervention outcomes to total economic benefit, based upon a compilation of published economic studies from the United States...
  49. ncbi Economic analysis of the diagnosis of smear-negative pulmonary tuberculosis in South Africa: incorporation of a new rapid test, FASTPlaqueTB, into the diagnostic algorithm
    H Albert
    Biotec Laboratories Ltd, c o National Health Laboratory Service, Cape Town, Western Cape, South Africa
    Int J Tuberc Lung Dis 8:240-7. 2004
  50. ncbi Costs of chronic obstructive pulmonary disease (COPD) in Italy: the SIRIO study (social impact of respiratory integrated outcomes)
    R W Dal Negro
    Divisione di Pneumologia, Ospedale Orlandi, Bussolengo, Verona, Italy
    Respir Med 102:92-101. 2008
    ..In conclusion, a significant reduction in the use of health resources and thus of COPD-related costs (both direct and indirect costs) was observed during the study, likely due to a more appropriate care and management of COPD patients...
  51. ncbi Cost-effectiveness and budget impact of obesity surgery in patients with type-2 diabetes in three European countries
    Roger Ackroyd
    Royal Hallamshire Hospital, General Surgery, Sheffield, South Yorkshire, UK
    Obes Surg 16:1488-503. 2006
  52. ncbi Cost-effectiveness of pharmacological interventions for smoking cessation: a literature review and a decision analytic analysis
    Fujian Song
    Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    Med Decis Making 22:S26-37. 2002
    ..The cost-effectiveness of adding NRT and bupropion SR to advice or counseling for smoking cessation is better than many other accepted health care interventions...
  53. ncbi Whither trial-based economic evaluation for health care decision making?
    Mark J Sculpher
    Centre for Health Economics, University of York, UK
    Health Econ 15:677-87. 2006
    ..It is argued that RCT evidence, with or without economic content, should be viewed as simply one of the sources of evidence, which must be placed in a broader framework of evidence synthesis and decision analysis...
  54. ncbi The cost effectiveness of combination antiretroviral therapy for HIV disease
    K A Freedberg
    Division of General Internal Medicine and the Partners AIDS Research Center, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    N Engl J Med 344:824-31. 2001
    ..We estimated the clinical benefits and cost effectiveness of three-drug antiretroviral regimens...
  55. pmc Costs and consequences of large-scale vector control for malaria
    Joshua O Yukich
    Department of Public Health and Epidemiology, Swiss Tropical Institute, PO Box, 4002 Basel, Switzerland
    Malar J 7:258. 2008
    ..Five large insecticide-treated net (ITN) programmes and two indoor residual spraying (IRS) programmes were compared using a standardized costing methodology...
  56. ncbi Cost-effectiveness of HIV treatment in resource-poor settings--the case of Côte d'Ivoire
    Sue J Goldie
    Department of Health Policy and Management, Program in Health Decision Science, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 355:1141-53. 2006
    ..As antiretroviral therapy is increasingly used in settings with limited resources, key questions about the timing of treatment and use of diagnostic tests to guide clinical decisions must be addressed...
  57. pmc Modelling the cost-effectiveness of introducing rapid syphilis tests into an antenatal syphilis screening programme in Mwanza, Tanzania
    P Vickerman
    London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Sex Transm Infect 82:v38-43. 2006
    ..This analysis estimates the relative cost-effectiveness of using these POC tests in the Mwanza syphilis screening intervention...
  58. ncbi The mission is remission: health economic consequences of achieving full remission with antidepressant treatment for depression
    P Sobocki
    Department of Learning, Informatics, Management and Ethics, Medical Management Centre, Karolinska Institutet, Stockholm, Sweden
    Int J Clin Pract 60:791-8. 2006
    ..01). We conclude that remission has a substantial health economic impact on patients treated for depression, which further strengthens the importance of aiming for full remission in the treatment of depression...
  59. pmc An evaluation of liquid-based cytology and human papillomavirus testing within the UK cervical cancer screening programme
    C Sherlaw-Johnson
    Clinical Operational Research Unit, University College London, Department of Mathematics, University College London, Gower Street, London WC1E 6BT, UK
    Br J Cancer 91:84-91. 2004
    ..British Journal of Cancer (2004) 91, 84-91. doi:10.1038/sj.bjc.6601884 Published online 25 May 2004..
  60. ncbi Cost analysis of ongoing care of patients with end-stage renal disease: the impact of dialysis modality and dialysis access
    Helen Lee
    Department of Economics, University of Calgary, Alberta, Canada
    Am J Kidney Dis 40:611-22. 2002
    ..Care of patients with end-stage renal disease (ESRD) is important and resource intense. To enable ESRD programs to develop strategies for more cost-efficient care, an accurate estimate of the cost of caring for patients with ESRD is needed...
  61. ncbi Cost and cost-effectiveness of universal screening for hearing loss in newborns
    E J Kezirian
    Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, 98195, USA
    Otolaryngol Head Neck Surg 124:359-67. 2001
    ..To estimate the cost and cost-effectiveness of universal newborn hearing screening...
  62. ncbi Cost effectiveness of initial endoscopy for dyspepsia in patients over age 50 years: a randomised controlled trial in primary care
    B C Delaney
    Department of Primary Care and General Practice, University of Birmingham, Medical School, Edgbaston
    Lancet 356:1965-9. 2000
    ..We aimed to determine the cost effectiveness of initial endoscopy compared with usual management in patients with dyspepsia over age 50 years presenting to their primary care physician...
  63. ncbi Cost-effectiveness of different combinations of bupropion SR dose and behavioral treatment for smoking cessation: a societal perspective
    Harold S Javitz
    Center for Health Sciences, SRI International, Menlo Park, Calif 94025, USA
    Am J Manag Care 10:217-26. 2004
  64. ncbi Using RE-AIM metrics to evaluate diabetes self-management support interventions
    Russell E Glasgow
    Kaiser Permanente Colorado, Clinical Research Unit, Denver, Colorado, USA
    Am J Prev Med 30:67-73. 2006
  65. ncbi Cost effectiveness of pneumococcal vaccination among Dutch infants: economic analysis of the seven valent pneumococcal conjugated vaccine and forecast for the 10 valent and 13 valent vaccines
    Mark H Rozenbaum
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, Netherlands
    BMJ 340:c2509. 2010
  66. ncbi The health economics of bladder cancer: a comprehensive review of the published literature
    Marc F Botteman
    Abt Associates Inc, Bethesda, Maryland 20814, USA
    Pharmacoeconomics 21:1315-30. 2003
  67. ncbi Valuing the ICECAP capability index for older people
    Joanna Coast
    University of Birmingham, Department of Health Economics, Public Health Building, Birmingham B15 2TT, UK
    Soc Sci Med 67:874-82. 2008
    ..Values that were estimated are feasible for use in practical applications of the index to measure the impact of health and social care interventions...
  68. ncbi Cost-effectiveness of rhythm versus rate control in atrial fibrillation
    Deborah A Marshall
    Center for Evaluation of Medicine, McMaster University and St Joseph s Hospital, Hamilton, Ontario, Canada
    Ann Intern Med 141:653-61. 2004
    ..Consequently, economic factors often play a role in guiding treatment selection...
  69. ncbi Cost measurement in economic evaluations of health care: whom to ask?
    Mandy Van Den Brink
    Department of Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands
    Med Care 42:740-6. 2004
  70. ncbi Comparing impact and cost-effectiveness of primary prevention strategies for lipid-lowering
    Mark J Pletcher
    University of California, San Francisco, San Francisco, California 94107, USA
    Ann Intern Med 150:243-54. 2009
    ..Lipid-lowering therapy is costly but effective at reducing coronary heart disease (CHD) risk...
  71. ncbi Criteria list for assessment of methodological quality of economic evaluations: Consensus on Health Economic Criteria
    Silvia Evers
    Department of Health Policy and Economics, Institute for Rehabilitation Research, Maastricht University, The Netherlands
    Int J Technol Assess Health Care 21:240-5. 2005
    ..The criteria list resulting from this CHEC project should be regarded as a minimum standard...
  72. ncbi Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature
    Olivier Ethgen
    WHO Collaborating Center for Public Health Aspects of Osteoarticular Diseases, Department of Public Health, Epidemiology, and Health Economics, University of Liege, Belgium, Liege, Belgium
    J Bone Joint Surg Am 86:963-74. 2004
    ..The objective of this study was to review the literature regarding the outcomes of total hip and knee arthroplasties as evaluated by health-related quality-of-life instruments...
  73. ncbi Effectiveness and cost effectiveness of human papillomavirus vaccine: a systematic review
    Fawziah Marra
    University of British Columbia, Vancouver, British Columbia, Canada
    Pharmacoeconomics 27:127-47. 2009
  74. ncbi The quality of life and cost utility of home nocturnal and conventional in-center hemodialysis
    Philip A McFarlane
    Department of Medicine, Home Dialysis Clinic, Inner City Health Research Unit, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Kidney Int 64:1004-11. 2003
    ..We hypothesized that individuals performing home nocturnal hemodialysis would have a higher quality of life and superior cost utility than in-center hemodialysis patients...
  75. ncbi Using effectiveness and cost-effectiveness to make drug coverage decisions: a comparison of Britain, Australia, and Canada
    Fiona M Clement
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 302:1437-43. 2009
    ..This study describes how that evidence has been used across 3 jurisdictions (Australia, Canada, and Britain) that have been at the forefront of evidence-based coverage internationally...
  76. ncbi Optimal cost-effectiveness decisions: the role of the cost-effectiveness acceptability curve (CEAC), the cost-effectiveness acceptability frontier (CEAF), and the expected value of perfection information (EVPI)
    Garry R Barton
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Value Health 11:886-97. 2008
    ..To explore and explain potentially counterintuitive results that can arise when analyzing multiple options...
  77. ncbi Community-based interventions for improving perinatal and neonatal health outcomes in developing countries: a review of the evidence
    Zulfiqar A Bhutta
    Department of Pediatrics and Child Health, Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    Pediatrics 115:519-617. 2005
    ..A comprehensive review of the evidence base for impact of interventions on neonatal health and survival in developing-country communities has not been reported...
  78. ncbi Cost and cost-effectiveness of community-based care for tuberculosis in Cape Town, South Africa
    E Sinanovic
    Health Economics Unit, University of Cape Town, Observatory, South Africa
    Int J Tuberc Lung Dis 7:S56-62. 2003
    ..Guguletu and Nyanga areas of Cape Town, South Africa...
  79. pmc Human health benefits from livestock vaccination for brucellosis: case study
    Felix Roth
    Swiss Centre for International Health, Swiss Tropical Institute, Basle, Switzerland
    Bull World Health Organ 81:867-76. 2003
    ..To estimate the economic benefit, cost-effectiveness, and distribution of benefit of improving human health in Mongolia through the control of brucellosis by mass vaccination of livestock...
  80. ncbi Reducing the global burden of hazardous alcohol use: a comparative cost-effectiveness analysis
    Dan Chisholm
    Department of Health System Financing, Expenditure and Resource Allocation, World Health Organization, Geneva, Switzerland
    J Stud Alcohol 65:782-93. 2004
    ..This study set out to estimate these costs and effects...
  81. ncbi Clinical impact and cost-effectiveness of co-trimoxazole prophylaxis in patients with HIV/AIDS in Côte d'Ivoire: a trial-based analysis
    Yazdan Yazdanpanah
    Service Universitaire des Maladies Infectieuses et du Voyageur, Centre Hospitalier de Tourcoing, Faculte de Medecine de Lille, France
    AIDS 19:1299-308. 2005
    ..In 2000, WHO/UNAIDS recommended co-trimoxazole prophylaxis for persons at early stages of HIV infection (WHO stage > or = 2) in sub-Saharan Africa...
  82. pmc Feasibility and cost-effectiveness of treating multidrug-resistant tuberculosis: a cohort study in the Philippines
    Thelma E Tupasi
    Tropical Disease Foundation, Manila, Philippines
    PLoS Med 3:e352. 2006
    ..However, evidence regarding the feasibility, effectiveness, cost, and cost-effectiveness of DOTS-Plus is still limited...
  83. pmc Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapy
    Samuel Shillcutt
    Andean Health and Development Saludesa, Quito, Ecuador
    Bull World Health Organ 86:101-10. 2008
    ..To evaluate the relative cost-effectiveness in different sub-Saharan African settings of presumptive treatment, field-standard microscopy and rapid diagnostic tests (RDTs) to diagnose malaria...
  84. ncbi Comparative cost-effectiveness of policy instruments for reducing the global burden of alcohol, tobacco and illicit drug use
    Dan Chisholm
    Evidence and Information for Policy, World Health Organisation, Geneva, Switzerland
    Drug Alcohol Rev 25:553-65. 2006
    ..These issues are the subject of the final section of this review...
  85. ncbi Willingness to pay for a quality-adjusted life year: in search of a standard
    R A Hirth
    Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor 48109 2029, USA
    Med Decis Making 20:332-42. 2000
    ..With the exception of HK, these far exceed the "rules of thumb" that are frequently used to determine whether an intervention produces an acceptable increase in health benefits in exchange for incremental expenditures...
  86. ncbi The economics of malaria in pregnancy--a review of the evidence and research priorities
    Eve Worrall
    Liverpool Associates in Tropical Health, Liverpool, UK
    Lancet Infect Dis 7:156-68. 2007
    ..Research priorities on the economics of malaria in pregnancy are identified...
  87. pmc Economic and programmatic aspects of congenital syphilis prevention
    George Schmid
    Research Scientist, Department of HIV AIDS, World Health Organization, 20 Avenue Appia, Geneva 27, Switzerland
    Bull World Health Organ 82:402-9. 2004
    ..The prevention of congenital syphilis should be a global priority; international agencies and national programmes should be committed to improving antenatal care (ANC) services including syphilis detection and prevention...
  88. ncbi The cost-effectiveness of improving malaria home management: shopkeeper training in rural Kenya
    C A Goodman
    Health Policy Unit, London School of Hygiene and Tropical Medicine, London, UK
    Health Policy Plan 21:275-88. 2006
  89. pmc The costs, benefits, and cost-effectiveness of interventions to reduce maternal morbidity and mortality in Mexico
    Delphine Hu
    Program in Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 2:e750. 2007
    ..S. Although national efforts have been made to improve maternal services in the last decade, it is unclear if Millennium Development Goal 5--to reduce maternal mortality by three-quarters by 2015--will be met...
  90. ncbi An outreach geriatric medication advisory service in residential aged care: a randomised controlled trial of case conferencing
    Maria Crotty
    Flinders University Department of Rehabilitation and Aged Care, Repatriation General Hospital, Daws Road, Daw Park, South Australia 5041, Australia
    Age Ageing 33:612-7. 2004
    ..efficient strategies are needed to provide specialist advice in nursing homes to ensure quality medical care. We describe a case conference intervention involving a multidisciplinary team of health professionals...
  91. ncbi Screening for HIV in health care settings: a guidance statement from the American College of Physicians and HIV Medicine Association
    Amir Qaseem
    American College of Physicians, 190 N Independence Mall West, Philadelphia, PA 19106, USA
    Ann Intern Med 150:125-31. 2009
    ..The American College of Physicians (ACP) developed this guidance statement to present the available evidence on screening for HIV in health care settings...
  92. pmc Screening men for abdominal aortic aneurysm: 10 year mortality and cost effectiveness results from the randomised Multicentre Aneurysm Screening Study
    S G Thompson
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 0SR
    BMJ 338:b2307. 2009
    ..To assess whether the mortality benefit from screening men aged 65-74 for abdominal aortic aneurysm decreases over time, and to estimate the long term cost effectiveness of screening...
  93. pmc Costs and consequences of the US Centers for Disease Control and Prevention's recommendations for opt-out HIV testing
    David R Holtgrave
    Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
    PLoS Med 4:e194. 2007
    ..In this paper, I estimate the costs and public health impact of opt-out HIV testing relative to testing accompanied by client-centered counseling, and relative to a more targeted counseling and testing strategy...
  94. ncbi Effectiveness and costs of interventions to lower systolic blood pressure and cholesterol: a global and regional analysis on reduction of cardiovascular-disease risk
    Christopher J L Murray
    Evidence and Information for Policy, World Health Organization, 27, Geneva, Switzerland
    Lancet 361:717-25. 2003
  95. ncbi Clinical effectiveness and cost-effectiveness of laparoscopic surgery for colorectal cancer: systematic reviews and economic evaluation
    A Murray
    Health Services Research Unit, University of Aberdeen, UK
    Health Technol Assess 10:1-141, iii-iv. 2006
  96. ncbi Randomized trial comparing traditional Chinese medical acupuncture, therapeutic massage, and self-care education for chronic low back pain
    D C Cherkin
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA
    Arch Intern Med 161:1081-8. 2001
    ..Traditional Chinese Medical acupuncture was relatively ineffective. Massage might be an effective alternative to conventional medical care for persistent back pain...
  97. pmc Need for differential discounting of costs and health effects in cost effectiveness analyses
    Werner B F Brouwer
    Institute for Medical Technology Assessment, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, Netherlands
    BMJ 331:446-8. 2005
  98. pmc The Internet for weight control in an obese sample: results of a randomised controlled trial
    Aine McConnon
    Food, Consumer Behaviour and Health Research Centre, University of Surrey, Guildford, Surrey, UK
    BMC Health Serv Res 7:206. 2007
    ..This study aims to determine the effectiveness and cost-effectiveness of an Internet-based resource for obesity management...
  99. ncbi Effectiveness and efficiency of guideline dissemination and implementation strategies
    J M Grimshaw
    Health Services Research Unit, University of Aberdeen, UK
    Health Technol Assess 8:iii-iv, 1-72. 2004
    ..To estimate the resource implications of these strategies. To develop a framework for deciding when it is efficient to develop and introduce clinical guidelines...
  100. ncbi The impact of male circumcision on HIV incidence and cost per infection prevented: a stochastic simulation model from Rakai, Uganda
    Ronald H Gray
    School of Public Health, University School of Medicine, Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205, USA
    AIDS 21:845-50. 2007
    ..To estimate the impact of male circumcision on HIV incidence, the number of procedures per HIV infection averted, and costs per infection averted...
  101. pmc The effectiveness and cost effectiveness of telephone counselling and the nicotine patch in a state tobacco quitline
    Jack F Hollis
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR 97227, USA
    Tob Control 16:i53-9. 2007
    ..We examined the effectiveness and cost effectiveness of offering callers single session versus multisession counselling, with or without free nicotine patches...

Research Grants80

  1. The Effect of Behavioral and Physiological Factors on Obesity Risk in Children
    Karen B Dorsey; Fiscal Year: 2012
    ..epidemiology, understanding health disparities, performance improvement in healthcare settings, and cost benefit analysis for the application of new medical technologies and treatment strategies...
  2. Gender Selectivity to Colon Cancer Chemoprevention by NSAIDS
    RAMESH K contact WALI; Fiscal Year: 2010
    ..These findings will have an important bearing on the healthcare recommendations for colon cancer chemoprevention which have to be cognizant of this gender selective efficacy for maximum cost-benefit potential of NSAIDS. ..
  3. Regulation of SKN-1 functions by insulin-like signaling in C. elegans
    THOMAS KEITH BLACKWELL; Fiscal Year: 2013
  4. Non-invasive evaluation of Non-alcoholic Steatohepatitis
    Michelle Lai; Fiscal Year: 2013
    ..It will give a predictive instrument for NASH as well as answer health policy questions that will have a substantial impact on the national health care budget, clinical practice and on patient health. ..
  5. Treating Low-Income Smokers in the Hospital Emergency Department
    Steven L Bernstein; Fiscal Year: 2013
    ..We will conduct a cost benefit analysis of the interventions...
  6. Comparative effectiveness of noninvasive cardiac imaging
    Marcelo F Di Carli; Fiscal Year: 2010
  7. Using Outcomes Analyses to Inform Implementation of NINDS Clinical Trials
    JAMES FRANCIS BURKE; Fiscal Year: 2013
  8. Randomized Trial of CVD Education and Problem-Solving Training in Urban Diabetics
    Felicia Hill-Briggs; Fiscal Year: 2012
  9. Feasibility, benefits, and acceptability of lowering the BAC standard in the US
    David W Eby; Fiscal Year: 2013
    ..g., driver, those who served the alcohol, alcohol manufacturer);and demographics. The results should be useful for states that want to reduce unintentional AID-related death and injuries by lowering the illegal BAC limit for driving. ..
  10. Disparities in Cancer Screening: The Role of Medicaid Policy
    LINDSAY MARIE SABIK; Fiscal Year: 2013
    ..The results will provide timely evidence on how Medicaid policy affects women's preventive healthcare utilization and health outcomes. ..
  11. Neurophysiological analysis of accumbens activity during risk-taking behavior
    JONATHAN ADAM SUGAM; Fiscal Year: 2012
    ..The results of these studies will provide invaluable insight into the neurocircuitry involved in normal risk-taking behavior and may have implications for the risk-taking involved in drug addiction. ..
  12. Re-engineering Methadone Treatment: A Randomized Clinical Trial
    Robert P Schwartz; Fiscal Year: 2013
    ..The public health impact of the proposed study will be high because the study may reveal that this new approach to treatment can prevent illicit drug use, HIV risk behavior, crime and overdose as compared to treatment as usual. ..
  13. FOR MOMS:Culturally Relevant Treatment for Perinatal Depression
    Nancy K Grote; Fiscal Year: 2013
    ..Performance Sites: Seattle King County Public Health Department, Seattle, WA University of Washington, Seattle WA ..
  14. Interventions to decrease HIV infectiousness in Uganda
    Connie L Celum; Fiscal Year: 2013
    ..5) Determine the incremental costs of HBCT and additional components in HBCT-plus for facilitated HIV care and counseling, and estimate the cost-benefit of community viral load reduction. ..
    Steven M Kymes; Fiscal Year: 2010
    ..Conducting sensitivity analyses with this decision model will permit evaluation of the consequences of a delay in case identification beyond the characteristics of the OHTS sample. ..
  16. Neurobiological Investigation of Decision Making in Rats
    Regina M Carelli; Fiscal Year: 2013
  17. The Effectiveness of Screening HIV-Infected Women for Anal Cancer Precursors
    Elizabeth Chiao; Fiscal Year: 2013
    ..The data will then be utilized to perform comprehensive cost-benefit analyses, which will direct clinical decision making on an optimal anal cancer screening approach for these women. ..
  18. Home Blood Pressure Telemonitoring and Case Management to Control Hypertension
    Karen L Margolis; Fiscal Year: 2013
  19. A Discrete Event Simulation Model of Environmental Exposures and Pediatric Asthma
    Jonathan I Levy; Fiscal Year: 2010
  20. A Comparison of Methadone Treatment Systems in California and British Columbia
    Bohdan Nosyk; Fiscal Year: 2013
    ..We expect that the model can subsequently be used as a tool by these and other jurisdictions to study hypothetical effects of policy changes on opioid treatment systems, intervention effects, and the clients they serve. ..
  21. Pathogenic and Protective T Cells in Toxoplasmosis
    George S Yap; Fiscal Year: 2013
    ..Insights from these investigations may become useful for vaccination strategies and the management of inflammatory and infectious diseases. ..
  22. Identifying Unnecessary Irradiation of Patients with Suspected Renal Colic
    Christopher L Moore; Fiscal Year: 2013
    ..Impact of the rule and cost benefit analysis will be evaluated to determine the comparative effectiveness of the derived rule...
  23. The Impact of Remote ICU Monitoring on Patient Outcomes and Processes of Care
    Peter M Cram; Fiscal Year: 2013
    ..Impact on VA: This evaluation will allow clinicians and administrators within the VA to understand the benefits and costs of implementing a remote ICU monitoring program. ..
  24. Linking infectious disease dynamics to seasonal animal movements
    REBECCA ANNE BARTEL; Fiscal Year: 2010
    ..Using a highly tractable insect-pathogen model system, my work will shed light on mechanisms that may be important for predicting future changes in the complex relationships between host populations and emerging infectious diseases. ..
  25. Biomarkers of Progression to Esophageal Adenocarcinoma
    GIULIANA JULIE IZZO; Fiscal Year: 2010
  26. Estrogen receptor beta protein:protein interactions following estrogen withdrawal
    NATASHA MOTT; Fiscal Year: 2013
    ..Overall, this proposal will reveal molecular mechanisms occurring during estrogen withdrawal that may alter the brain's receptivity to HT. ..
  27. Cost, Benefit &Regulation of Buprenorphine Treatment for Medicaid Beneficiaries
    Robin E Clark; Fiscal Year: 2012
    ..New knowledge gained from the study will be useful for developing more cost-effective policies and practices for managing opioid substitution treatment. ..
  28. Older Adult Safety in Surgery (OASIS)
    Alok Kapoor; Fiscal Year: 2012
    ..If the conclusions about the value of high potency prophylaxis changes in the subpopulations, the method outlined would represent a major innovation in the perioperative assessment of older adult surgical patient. ..
  29. The Intra-household Distribution of Food and Health Resources amongst Children
    Achyuta Adhvaryu; Fiscal Year: 2013
    ..Answering this question-are we helping or hurting other children in the household through targeted interventions?-is essential to the design and improved cost-benefit analysis of childhood nutrition programs around the world. ..
  30. Transfusion Infection Pediatric Prospective Study (TRIPPS)
    NAOMI L LUBAN; Fiscal Year: 2011
    ..This application focuses on infants and children, a vulnerable and heretofore poorly studied recipient group. ..
  31. R01D: An Interdisciplinary Perspective: A Social Science Examination of Oncoferti
    LINDA LEAH EMANUEL; Fiscal Year: 2011
    ..abstract_text> ..
  32. DDT &PBDE exposure, puberty onset and neurodevelopment in Mexican-American girls
    Brenda Eskenazi; Fiscal Year: 2013
    ..abstract_text> ..
  33. Monroe County, New York School Based Influenza Immunization Program
    ANDREW S DONIGER; Fiscal Year: 2010
    ..Standard-of-care and High-Intensity vs. Low- Intensity interventions is further strengthened by a carefully crafted set of economic studies and modeling, quantitative surveys, and qualitative research. ..
  34. Relation of Primary Care Practice Variation to the Prevention of CVD and Diabetes
    THOMAS MICHAEL VOGT; Fiscal Year: 2010
    ..This information has the potential to evaluate the relative trade- offs between costs and benefits of various guidelines, and to provide powerful motivating information to support adherence to evidence-based guidelines. ..
  35. Can Concurrent Hospice Care and Cancer Treatment Achieve Superior Outcomes?
    Vincent Mor; Fiscal Year: 2013
    ..If this observational study replicates the published small scale randomized trial, VHA not only has the evidence for more aggressively pursuing concurrent care but the VA is poised to influence national policy on this topic. ..
  36. Intensive glycemic control for congestive heart failure exacerbation
    KATHLEEN MARIE DUNGAN; Fiscal Year: 2012
    ..Preliminary studies suggest that patients with worse diabetes control have higher mortality. The present study will address whether better early diabetes control improves hospital outcomes. ..
  37. CHOICES+: Preconception approach to reducing alcohol &tobacco-exposed pregnancy
    Mary Marden Velasquez; Fiscal Year: 2011
    ..Results from this study will inform and advance future efforts in the service of promoting healthy prenatal behavior and reducing the prevalence of alcohol and tobacco-exposed pregnancies. ..
  38. Regular and Off-Shift Nursing: Impacts on Patient Outcomes and Cost of Care
    Ciaran S Phibbs; Fiscal Year: 2013
    ..We will re-run models using the cost of patient encounters as the dependent variable to estimate the potential cost savings. ..
  39. Global Cardiovascular Disease Policy Model for Screening Prevention and Treatment
    Thomas A Gaziano; Fiscal Year: 2012
    ..It will incorporate the sensitivity, specificity, costs, and benefits of screening, and the costs and benefits of early intervention. ..
  40. Evaluating a Web-based Child Passenger Safety Program: Safety in Seconds v 2.0
    Andrea C Gielen; Fiscal Year: 2013
    ..450 JH-PTS, 600 AR-PED), including baseline and 6-month follow up assessments and CSS observations;c) a cost benefit analysis of the program's expected financial benefit from the perspective of a third party payer of medical ..
    DENISE D WALKER-SCHRAMM; Fiscal Year: 2013
  42. A Randomized Trial of Interim Methadone and Patient Navigation Initiated in Jail
    Robert P Schwartz; Fiscal Year: 2013
    ..The proposed study will yield novel results that can be used to inform public policy in instituting more effective and cost-effective approaches to the problem of post-release relapse to opioid use in jail detainees. ..
  43. Advancing Spatial Evaluation Methods to Improve Healthcare Efficiency and Quality
    Luc Anselin; Fiscal Year: 2013
    ..abstract_text> ..
    Ann M Graybiel; Fiscal Year: 2013
  45. Activity-Dependent Influences on Auditory Circuits
    Daniel B Polley; Fiscal Year: 2013
  46. Advanced Training Health Service Research
    Mark Pauly; Fiscal Year: 2012
  47. Early Child Development Programs: Effective Interventions for Human Development
    Jere R Behrman; Fiscal Year: 2013
    ..g., vouchers), rich data described above and possible implications for other middle-income as well as high-income countries. ..
  48. Efficacy of Drug-HIV counseling among IDU at Methadone clinics in Jakarta
    David S Metzger; Fiscal Year: 2012
    ..In settings such as Jakarta, data regarding the costs and benefits of integrated drug and risk counseling have critical public heath relevance. ..
    KATHLEEN MICHELE MAZOR; Fiscal Year: 2011
    ..Recommendations for modifying oral messages so that they are easily comprehensible will be developed, and the impact of specific enhancements will be tested in a randomized experiment. ..
  50. Behavioral Couples Group Therapy for Alcoholic Patients: Clinical Cost Outcomes
    TIMOTHY JAMES O'FARRELL; Fiscal Year: 2013
    ..Given the likely differences in cost of treatment delivery between the 2 interventions, we will also examine the comparative cost- benefit and cost-effectiveness of the 2 intervention packages. ..
  51. Depression Screening RCT in ACS patients: Quality of Life and Cost Outcomes
    Karina W Davidson; Fiscal Year: 2013
    ..Health-related quality of life, depressive symptoms, and costs will be obtained from all patients, so that the benefits and the costs of these three different depression screening strategies can be compared. ..
  52. Modeling prostate cancer control: prevention, screening, treatment, followup care
    Alexander Tsodikov; Fiscal Year: 2013
    ..We plan to conduct the research using a coordinated comparative modeling approach in which independent models are standardized and made comparable by the use of common inputs and the implementation of common "base case" scenarios. . ..
  53. The effectiveness of copper surfaces in reducing healthcare acquired infections
    DANIEL ZACHARY USLAN; Fiscal Year: 2013
    ..This project therefore addresses the recent focus of AHRQ on novel approaches to prevention and reduction of healthcare-associated infections. ..
  54. Evaluating South Dakota's 24/7 Sobriety Program
    BEAU GRIFFIN KILMER; Fiscal Year: 2013
  55. E-mail and Web-Based Physician Education Program on the Dissemination of Off-Labe
    Deborah Hales; Fiscal Year: 2013
  56. ED Disability Diagnostic Tool: An HIT Feasibility Study
    Lori Ann Post; Fiscal Year: 2013
    ..abstract_text> ..
    Jon Morgenstern; Fiscal Year: 2011
    ..Results from this study should guide dissemination of this promising intervention. ..
  58. Quality and Costs in Hospitals: What Can We Learn from Medicare Patients?
    John A Romley; Fiscal Year: 2010
  59. Pathogenic and Protective T Cells in Toxoplasmosis
    George Yap; Fiscal Year: 2009
    ..gondii vaccination and infection. We will critically assess the costs and benefits of IL-12 signaling on the immediate and recall CD8 protective response to re-infection. ..
  60. Mathematical models of H. pylori gastric colonization
    Martin J Blaser; Fiscal Year: 2013
    ..Through such analyses, we hope to create the basis for a deeper understanding of how microbes are able to persist for long periods in their human hosts. ..
  61. Long-term Outcomes and Economic Impact of the Detention to Community Model
    CYNTHIA LYN ROWE; Fiscal Year: 2010
  62. A spatially-modulated scatter imaging system to detect tumor-associated stroma
    WENDY ANNE WELLS; Fiscal Year: 2010
  63. Novel minimally invasive assessment of gastrointestinal inflammation in food alle
    Glenn Furuta; Fiscal Year: 2009
  64. Estimates of the Value of Life Using Air Bag Regulations as a Quasi-Experiment
    CHRISTOPHER ROHLFS; Fiscal Year: 2009
    ..By improving the accuracy of these benefit estimates, this study will contribute toward improving the accuracy of government decision-making in these areas. ..
    Paul Williams; Fiscal Year: 2002
    ..1%). Additionally, a detectable reduction in breast cancer risk as small as 1.5% per mile run in women is calculated, which is below the 1.7% reduction in risk estimated from other published data. ..
    A Washington; Fiscal Year: 1993
    ..The information generated and the analyses performed during this investigation will provide the necessary groundwork for the development and implementation of preference-based clinical guidelines for the use of prenatal diagnostics...
  67. Software for cost-benefit analysis of LBP interventions
    Nancy Nelson; Fiscal Year: 2006
    ..The software will encourage adoption of methods for preventing occupational low back disorders. [unreadable] [unreadable] [unreadable] [unreadable]..
  68. Developing a Strategic Approach to Management of Adolescents with PID
    Maria Trent; Fiscal Year: 2009
    ELENA VESSELINOV; Fiscal Year: 2009
  70. Dopaminergic modulation of cost/benefit decision making during aging
    Paul Phillips; Fiscal Year: 2009
    ..How these changes impact economic choices is unknown. The proposed work will use behavioral and neurochemical methods to study age-related changes in economic decision making in rats. ..
    Brian Gage; Fiscal Year: 2001
    ..abstract_text> ..
  72. Cost-Effectiveness of Domestic Violence Interventions
    Mary Zachary; Fiscal Year: 2003
    Timothy Wheeler; Fiscal Year: 2005
    ..Develop predictive and mechanistic multivariate models to evaluate the effectiveness of single versus dual phase correction of Class II malocclusion using multivariate regression models, fuzzy analysis, and cost-effectiveness analysis. ..
    Jane Lipscomb; Fiscal Year: 2001
    ..abstract_text> ..
  75. Cost and Adherence in Drug Abuse Treatment
    KENNETH STOLLER; Fiscal Year: 2007
    ..This accomplishment will document my transition to the status of an independent patient-oriented researcher and recognized expert in the field of drug abuse treatment. [unreadable] [unreadable] [unreadable] [unreadable]..
  76. Improving Pressure Ulcer Care in Nursing Homes
    Barbara Bates Jensen; Fiscal Year: 2006
    ..guidelines in NHs, which builds on her clinical and teaching experience; 3) cost effectiveness and cost benefit analysis and 4) operations research modeling such that associated costs and staffing resources required for ..
  77. Automated Development of Electronic Data Capture for Clinical Trials
    Mansur R Kabuka; Fiscal Year: 2010
    ..Standard data representations based on CDISC standards are used by the tools and components of the AD-EDC System to support interoperability and persistence. ..
    Sherrill Slichter; Fiscal Year: 1992
    ..In summary, this Program Project Grant represents a multi-faceted approach to increasing donor involvement in blood center programs...
    PAUL CARBONE; Fiscal Year: 1993
    ..the development of new breast education and screening programs. Various methods will be used to ensure a high response rate, including raffles for items such as gift certificates at local restaurants, and secondarily, telephone followup...
    Maria Testa; Fiscal Year: 1993
    ..Future research will also be applied towards prevention; for example, through the development of educational strategies based on the health belief variables examined in this study...