emigration and immigration

Summary

Summary: The process of leaving one's country to establish residence in a foreign country.

Top Publications

  1. pmc Distinguishing migration from isolation: a Markov chain Monte Carlo approach
    R Nielsen
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Genetics 158:885-96. 2001
  2. doi Genetic discontinuity between local hunter-gatherers and central Europe's first farmers
    B Bramanti
    Institute for Anthropology, University of Mainz, Mainz, Germany
    Science 326:137-40. 2009
  3. doi The archaeogenetics of Europe
    Pedro Soares
    Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK
    Curr Biol 20:R174-83. 2010
  4. pmc Genes mirror geography within Europe
    John Novembre
    Department of Ecology and Evolutionary Biology, Interdepartmental Program in Bioinformatics, University of California Los Angeles, Los Angeles, California 90095, USA
    Nature 456:98-101. 2008
  5. pmc A predominantly neolithic origin for European paternal lineages
    Patricia Balaresque
    Department of Genetics, University of Leicester, Leicester, United Kingdom
    PLoS Biol 8:e1000285. 2010
  6. ncbi Obesity among US immigrant subgroups by duration of residence
    Mita Sanghavi Goel
    Division of General Internal Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill
    JAMA 292:2860-7. 2004
  7. pmc Genetic variation and population structure in native Americans
    Sijia Wang
    The Galton Laboratory, Department of Biology, University College London, London, United Kingdom
    PLoS Genet 3:e185. 2007
  8. pmc Interpreting principal component analyses of spatial population genetic variation
    John Novembre
    Department of Human Genetics, University of Chicago, 920 E 58th Street, CLSC 5th floor, Chicago, Illinois 60637, USA
    Nat Genet 40:646-9. 2008
  9. pmc Mitochondrial population genomics supports a single pre-Clovis origin with a coastal route for the peopling of the Americas
    Nelson J R Fagundes
    Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, RS, 91619 900, Brazil
    Am J Hum Genet 82:583-92. 2008
  10. pmc The financial cost of doctors emigrating from sub-Saharan Africa: human capital analysis
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, Canada
    BMJ 343:d7031. 2011

Research Grants

Detail Information

Publications422 found, 100 shown here

  1. pmc Distinguishing migration from isolation: a Markov chain Monte Carlo approach
    R Nielsen
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    Genetics 158:885-96. 2001
    ..The use of the method is illustrated in an application to mitochondrial DNA sequence data from a fish species: the threespine stickleback (Gasterosteus aculeatus)...
  2. doi Genetic discontinuity between local hunter-gatherers and central Europe's first farmers
    B Bramanti
    Institute for Anthropology, University of Mainz, Mainz, Germany
    Science 326:137-40. 2009
    ..Together, these analyses provide persuasive evidence that the first farmers were not the descendants of local hunter-gatherers but immigrated into central Europe at the onset of the Neolithic...
  3. doi The archaeogenetics of Europe
    Pedro Soares
    Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK
    Curr Biol 20:R174-83. 2010
    ....
  4. pmc Genes mirror geography within Europe
    John Novembre
    Department of Ecology and Evolutionary Biology, Interdepartmental Program in Bioinformatics, University of California Los Angeles, Los Angeles, California 90095, USA
    Nature 456:98-101. 2008
    ..In addition, the results are relevant to the prospects of genetic ancestry testing; an individual's DNA can be used to infer their geographic origin with surprising accuracy-often to within a few hundred kilometres...
  5. pmc A predominantly neolithic origin for European paternal lineages
    Patricia Balaresque
    Department of Genetics, University of Leicester, Leicester, United Kingdom
    PLoS Biol 8:e1000285. 2010
    ....
  6. ncbi Obesity among US immigrant subgroups by duration of residence
    Mita Sanghavi Goel
    Division of General Internal Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill
    JAMA 292:2860-7. 2004
    ..The prevalence of obesity has increased substantially since the 1980s. While immigrants are the fastest growing segment of the US population, little is known about obesity or clinician counseling about diet and exercise in this group...
  7. pmc Genetic variation and population structure in native Americans
    Sijia Wang
    The Galton Laboratory, Department of Biology, University College London, London, United Kingdom
    PLoS Genet 3:e185. 2007
    ..These findings offer new insights into the process of population dispersal and differentiation during the peopling of the Americas...
  8. pmc Interpreting principal component analyses of spatial population genetic variation
    John Novembre
    Department of Human Genetics, University of Chicago, 920 E 58th Street, CLSC 5th floor, Chicago, Illinois 60637, USA
    Nat Genet 40:646-9. 2008
    ..Our findings aid interpretation of PCA results and suggest how PCA can help correct for continuous population structure in association studies...
  9. pmc Mitochondrial population genomics supports a single pre-Clovis origin with a coastal route for the peopling of the Americas
    Nelson J R Fagundes
    Faculdade de Biociencias, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, RS, 91619 900, Brazil
    Am J Hum Genet 82:583-92. 2008
    ..These results support a pre-Clovis occupation of the New World, suggesting a rapid settlement of the continent along a Pacific coastal route...
  10. pmc The financial cost of doctors emigrating from sub-Saharan Africa: human capital analysis
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, Canada
    BMJ 343:d7031. 2011
    ..To estimate the lost investment of domestically educated doctors migrating from sub-Saharan African countries to Australia, Canada, the United Kingdom, and the United States...
  11. doi Medical schools in sub-Saharan Africa
    Fitzhugh Mullan
    The George Washington University, Washington, DC 20037, USA
    Lancet 377:1113-21. 2011
    ..Ten recommendations provide guidance for efforts to strengthen medical education in sub-Saharan Africa...
  12. ncbi Who infects whom? HIV-1 concordance and discordance among migrant and non-migrant couples in South Africa
    Mark N Lurie
    South African Medical Research Council, HIV Prevention and Vaccine Research Unit, Durban, South Africa
    AIDS 17:2245-52. 2003
    ..To measure HIV-1 discordance among migrant and non-migrant men and their rural partners, and to estimate the relative risk of infection from inside versus outside primary relationships...
  13. pmc The initial peopling of the Americas: a growing number of founding mitochondrial genomes from Beringia
    Ugo A Perego
    Sorenson Molecular Genealogy Foundation, Salt Lake City, Utah 84115, USA
    Genome Res 20:1174-9. 2010
    ....
  14. ncbi Prevalence of serious mental disorder in 7000 refugees resettled in western countries: a systematic review
    Mina Fazel
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
    Lancet 365:1309-14. 2005
    ..We did a systematic review of surveys about these disorders in general refugee populations in western countries...
  15. pmc Ancient DNA from European early neolithic farmers reveals their near eastern affinities
    Wolfgang Haak
    Australian Centre for Ancient DNA, School of Earth and Environmental Sciences, University of Adelaide, Adelaide, Australia
    PLoS Biol 8:e1000536. 2010
    ....
  16. ncbi Language-tree divergence times support the Anatolian theory of Indo-European origin
    Russell D Gray
    Department of Psychology, University of Auckland, Private Bag 92019, Auckland 1020, New Zealand
    Nature 426:435-9. 2003
    ..These results were robust to changes in coding procedures, calibration points, rooting of the trees and priors in the bayesian analysis...
  17. ncbi Risk factors for coronary heart disease among immigrant women from Iran and Turkey, compared to women of Swedish ethnicity
    Achraf Daryani
    Unit for Clinical Nutrition Research, Department of Public Health and Caring Sciences, Uppsala University, Sweden
    Ethn Dis 15:213-20. 2005
    ..The aim of the study was to compare a group of immigrant women from the Middle East living in Sweden to Swedish-born controls regarding the prevalence of certain cardiovascular risk factors...
  18. doi Contrasting patterns of nuclear and mtDNA diversity in Native American populations
    Ning Ning Yang
    Department of Genetics, Evolution and Environment, University College London, UK
    Ann Hum Genet 74:525-38. 2010
    ..These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions...
  19. pmc Risk factors for mortality from imported falciparum malaria in the United Kingdom over 20 years: an observational study
    Anna M Checkley
    HPA Malaria Reference Laboratory and London School of Hygiene and Tropical Medicine, London WC1B 3DP, UK
    BMJ 344:e2116. 2012
    ..To determine which travellers with malaria are at greatest risk of dying, highlighting factors which can be used to target health messages to travellers...
  20. ncbi Are some perinatal deaths in immigrant groups linked to suboptimal perinatal care services?
    Birgitta Essen
    Department of Obstetrics and Gynaecology, Malmo University Hospital, Lund University, Sweden
    BJOG 109:677-82. 2002
    ..To test the hypothesis that suboptimal factors in perinatal care services resulting in perinatal deaths were more common among immigrant mothers from the Horn of Africa, when compared with Swedish mothers...
  21. ncbi Genetic evidence supports demic diffusion of Han culture
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences and Morgan Tan International Center for Life Sciences, Fudan University, Shanghai 200433, China
    Nature 431:302-5. 2004
    ..16 billion (2000 census), and are by far the largest ethnic group in the world. The expansion process of Han culture is thus of great interest to researchers in many fields...
  22. pmc Explaining seasonal fluctuations of measles in Niger using nighttime lights imagery
    N Bharti
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    Science 334:1424-7. 2011
    ..In addition to epidemiological applications, the ability to measure fine-scale changes in population density has implications for public health, crisis management, and economic development...
  23. doi Human resources for health in southeast Asia: shortages, distributional challenges, and international trade in health services
    Churnrurtai Kanchanachitra
    Mahidol University, Nakhon Pathom, Thailand
    Lancet 377:769-81. 2011
    ..There is also a need for improved dialogue between the health and trade sectors on how to balance economic opportunities associated with trade in health services with domestic health needs and equity issues...
  24. pmc All-cause and cause-specific mortality of immigrants and native born in the United States
    G K Singh
    Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Executive Plaza North, Suite 343, 6130 Executive Blvd, MSC 7352, Bethesda, MD 20892 7352, USA
    Am J Public Health 91:392-9. 2001
    ..This study examined whether US-born people and immigrants 25 years or older differ in their risks of all-cause and cause-specific mortality and whether these differentials, if they exist, vary according to age, sex, and race/ethnicity...
  25. pmc High-resolution mtDNA evidence for the late-glacial resettlement of Europe from an Iberian refugium
    Luisa Pereira
    IPATIMUP Instituto de Patologia e Imunologia Molecular da Universidade do Porto, 4200 465 Porto, Portugal
    Genome Res 15:19-24. 2005
    ..This shows that a large fraction of the maternal ancestry of modern Europeans traces back to the expansion of hunter-gatherer populations at the end of the last Ice Age...
  26. doi The late Pleistocene dispersal of modern humans in the Americas
    Ted Goebel
    Center for the Study of the First Americans, Department of Anthropology, Texas A and M University, 4352 TAMU, College Station, TX 77843 4352, USA
    Science 319:1497-502. 2008
    ..If this is the time of colonization, geological data from western Canada suggest that humans dispersed along the recently deglaciated Pacific coastline...
  27. doi Climate change and postglacial human dispersals in southeast Asia
    Pedro Soares
    Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK
    Mol Biol Evol 25:1209-18. 2008
    ..This suggests that global warming and sea-level rises at the end of the Ice Age, 15,000-7,000 years ago, were the main forces shaping modern human diversity in the region...
  28. pmc A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe
    Natalie M Myres
    Sorenson Molecular Genealogy Foundation, Salt Lake City, UT, USA
    Eur J Hum Genet 19:95-101. 2011
    ....
  29. ncbi The metrics of the physician brain drain
    Fitzhugh Mullan
    George Washington University School of Public Health and Health Services, Washington, DC 20006, USA
    N Engl J Med 353:1810-8. 2005
    ..Although the recipient nations and the immigrating physicians benefit from this migration, less developed countries lose important health capabilities as a result of the loss of physicians...
  30. ncbi Do African immigrants living in France have long-term malarial immunity?
    Olivier Bouchaud
    Department of Infectious and Tropical Diseases, and Parasitology, Hopital Bichat Claude Bernard, Paris, France
    Am J Trop Med Hyg 72:21-5. 2005
    ..falciparum. These results suggest the persistence of acquired immunity to P. falciparum malaria after several years of non-exposure in African immigrants...
  31. ncbi Paternal and maternal lineages in the Balkans show a homogeneous landscape over linguistic barriers, except for the isolated Aromuns
    E Bosch
    Unitat de Biologia Evolutiva, Universitat Pompeu Fabra, Barcelona, Spain
    Ann Hum Genet 70:459-87. 2006
    ..The homogeneity of Balkan populations prevented testing for the origin of the Aromuns, although a significant Roman contribution can be ruled out...
  32. ncbi Why the(y) wait? Key informant understandings of factors contributing to late presentation and poor utilization of HIV health and social care services by African migrants in Britain
    F M Burns
    Centre for Sexual Health and HIV Research, University College London
    AIDS Care 19:102-8. 2007
    ..Community involvement should include input to ensure there is: better cultural understanding within the health care system; normalization of the HIV testing process; and a clear message on the effectiveness of therapy...
  33. ncbi Trauma, post-migration living difficulties, and social support as predictors of psychological adjustment in resettled Sudanese refugees
    Robert Schweitzer
    School of Psychology and Counselling, Queensland University of Technology, Brisbane, Australia
    Aust N Z J Psychiatry 40:179-87. 2006
    ..This paper explores the impact of pre-migration trauma, post-migration living difficulties and social support on the current mental health of 63 resettled Sudanese refugees...
  34. ncbi History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variation
    Sarah A Tishkoff
    Department of Biology, University of Maryland, USA
    Mol Biol Evol 24:2180-95. 2007
    ....
  35. pmc Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy
    Eur J Hum Genet 18:800-7. 2010
    ....
  36. ncbi Ethnic-immigrant differentials in health behaviors, morbidity, and cause-specific mortality in the United States: an analysis of two national data bases
    Gopal K Singh
    National Institutes of Health, Bethesda, MD 20892 8316, USA
    Hum Biol 74:83-109. 2002
    ....
  37. ncbi Loss of health professionals from sub-Saharan Africa: the pivotal role of the UK
    J B Eastwood
    Department of Cellular and Molecular Medicine, St George s Hospital Medical School, London SW17 0RE, UK
    Lancet 365:1893-900. 2005
    ..We suggest some practical measures to these ends. These include action the UK could take on its own, with the African countries most affected, and with other developed countries and WHO...
  38. ncbi Insights into the 'healthy immigrant effect': health status and health service use of immigrants to Canada
    James Ted McDonald
    Department of Economics, University of New Brunswick, PO Box 4400, Fredericton, NB E3B 5A3, Canada
    Soc Sci Med 59:1613-27. 2004
    ....
  39. ncbi Tracing past human male movements in northern/eastern Africa and western Eurasia: new clues from Y-chromosomal haplogroups E-M78 and J-M12
    Fulvio Cruciani
    Dipartimento di Genetica e Biologia Molecolare, Sapienza Universita di Roma, Rome, Italy, and Laboratoire d Immunologie, Hopital de Sainte Marguerite, Marseille, France
    Mol Biol Evol 24:1300-11. 2007
    ..Our results not only provide a refinement of previous evolutionary hypotheses but also well-defined time frames for past human movements both in northern/eastern Africa and western Eurasia...
  40. doi Pregnancy outcome of migrant women and integration policy: a systematic review of the international literature
    Paola Bollini
    Services for Medical Research forMed, Evolene, Switzerland
    Soc Sci Med 68:452-61. 2009
    ..Immigrant women clearly need targeted attention to improve the health of their newborn, but a deep societal change is also necessary to integrate and respect immigrant communities in receiving societies...
  41. doi Distinctive Paleo-Indian migration routes from Beringia marked by two rare mtDNA haplogroups
    Ugo A Perego
    Dipartimento di Genetica e Microbiologia, Universita di Pavia, 27100 Pavia, Italy
    Curr Biol 19:1-8. 2009
    ..In this study, we have instead identified and analyzed mtDNAs belonging to two rare Native American haplogroups named D4h3 and X2a...
  42. doi Paleo-Eskimo mtDNA genome reveals matrilineal discontinuity in Greenland
    M Thomas P Gilbert
    Center for Ancient Genetics, Department of Biology, Universitetsparken 15, DK 2100 Copenhagen, Denmark
    Science 320:1787-9. 2008
    ..This result suggests that the earliest migrants into the New World's northern extremes derived from populations in the Bering Sea area and were not directly related to Native Americans or the later Neo-Eskimos that replaced them...
  43. ncbi Prevalence of type 2 diabetes mellitus, other cardiovascular risk factors, and cardiovascular disease in Turkish and Moroccan immigrants in North West Europe: a systematic review
    P J M Uitewaal
    Department of Health Policy and Management, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands
    Prev Med 39:1068-76. 2004
    ....
  44. doi Tuberculosis among foreign-born persons in the United States
    Kevin P Cain
    Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS E 10, Atlanta, GA 30333, USA
    JAMA 300:405-12. 2008
    ..Foreign-born persons accounted for 57% of all tuberculosis (TB) cases in the United States in 2006. Current TB control strategies have not sufficiently addressed the high levels of TB disease and latent TB infection in this population...
  45. ncbi The impact of migration on HIV-1 transmission in South Africa: a study of migrant and nonmigrant men and their partners
    Mark N Lurie
    South African Medical Research Council, HIV Prevention and Vaccine Research Unit, Durban, South Africa
    Sex Transm Dis 30:149-56. 2003
    ..To investigate the association between migration and HIV infection among migrant and nonmigrant men and their rural partners...
  46. ncbi Epidemiology of Chagas disease in non-endemic countries: the role of international migration
    Gabriel A Schmunis
    Pan American Health Organization World Health Organization, 525 23rd Street, NW Washington, DC 20037, USA
    Mem Inst Oswaldo Cruz 102:75-85. 2007
    ..cruzi infection, prevent tainting the blood supply with T. cruzi, and implement secondary prevention of congenital Chagas disease...
  47. pmc The role of human movement in the transmission of vector-borne pathogens
    Steven T Stoddard
    Entomology, University of California, Davis, California, United States of America
    PLoS Negl Trop Dis 3:e481. 2009
    ..Here we develop a conceptual model to evaluate the importance of variation in exposure due to individual human movements for pathogen transmission, focusing on mosquito-borne dengue virus...
  48. ncbi Emergency room utilization in Copenhagen: a comparison of immigrant groups and Danish-born residents
    Marie Norredam
    Department of Health Services Research, Institute of Public Health, University of Copenhagen Denmark
    Scand J Public Health 32:53-9. 2004
    ..The aim of the study was to investigate whether utilization of the emergency room differed between immigrant groups and Danish-born residents in Copenhagen, Denmark...
  49. pmc Y-chromosome evidence for differing ancient demographic histories in the Americas
    Maria Catira Bortolini
    Department of Biology, University College, London, United Kingdom
    Am J Hum Genet 73:524-39. 2003
    ..Age estimates based on Y-chromosome microsatellite diversity place the initial settlement of the American continent at approximately 14,000 years ago, in relative agreement with the age of well-established archaeological evidence...
  50. doi The human genetic history of the Americas: the final frontier
    Dennis H O'Rourke
    Department of Anthropology, University of Utah, 270 S 1400 E, rm 102, Salt Lake City, UT 84112, USA
    Curr Biol 20:R202-7. 2010
    ....
  51. doi Global distribution of Y-chromosome haplogroup C reveals the prehistoric migration routes of African exodus and early settlement in East Asia
    Hua Zhong
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, PR China
    J Hum Genet 55:428-35. 2010
    ..The northward expansion of Hg C in East Asia started approximately 40 thousand of years ago (KYA) along the coastline of mainland China and reached Siberia approximately 15 KYA and finally made its way to the Americas...
  52. ncbi Low overall mortality of Turkish residents in Germany persists and extends into a second generation: merely a healthy migrant effect?
    O Razum
    Department of Tropical Hygiene and Public Health, Heidelberg University, Germany
    Trop Med Int Health 3:297-303. 1998
    ..To test the hypothesis that as a minority with lower socio-economic status, Turkish residents in Germany might experience a higher mortality than Germans...
  53. ncbi The genetic legacy of Paleolithic Homo sapiens sapiens in extant Europeans: a Y chromosome perspective
    O Semino
    Dipartimento di Genetica e Microbiologia, Universita di Pavia, Via Ferrata 1, 27100 Pavia, Italy
    Science 290:1155-9. 2000
    ....
  54. pmc Prolonged Plasmodium falciparum infection in immigrants, Paris
    Eric D'Ortenzio
    Centre Hospitalier Universitaire Bichat Claude Bernard, Paris, France
    Emerg Infect Dis 14:323-6. 2008
    ..falciparum infection in immigrant travelers. Results suggest that P. falciparum infection should be systematically suspected, even months after travel, especially in pregnant women and first-arrival immigrants...
  55. pmc On the edge of Bantu expansions: mtDNA, Y chromosome and lactase persistence genetic variation in southwestern Angola
    Margarida Coelho
    IPATIMUP, Instituto de Patologia e Imunologia Molecular da Universidade do Porto, R Dr Roberto Frias s n, 4200 465 Porto, Portugal
    BMC Evol Biol 9:80. 2009
    ....
  56. ncbi Globalization of infectious diseases: the impact of migration
    Brian D Gushulak
    Medical Services Branch, Citizenship and Immigration Canada, Ottawa, Ontario, Canada
    Clin Infect Dis 38:1742-8. 2004
    ....
  57. pmc Ancient human genome sequence of an extinct Palaeo-Eskimo
    Morten Rasmussen
    Centre for GeoGenetics, Natural History Museum of Denmark and Department of Biology, University of Copenhagen, Universitetsparken 15, DK 2100 Copenhagen, Denmark
    Nature 463:757-62. 2010
    ..This provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit...
  58. ncbi High-resolution SNPs and microsatellite haplotypes point to a single, recent entry of Native American Y chromosomes into the Americas
    Stephen L Zegura
    Department of Anthropology, University of Arizona, USA
    Mol Biol Evol 21:164-75. 2004
    ..Divergence dates between the Altai plus North Asians versus the Native American population system ranged from 10,100 to 17,200 years for all lineages, precluding a very early entry into the Americas...
  59. pmc The Levant versus the Horn of Africa: evidence for bidirectional corridors of human migrations
    J R Luis
    Department of Biological Sciences, Florida International University, Miami, 33199, USA
    Am J Hum Genet 74:532-44. 2004
    ....
  60. ncbi Female genital mutilation in the context of migration: experience of African women with the Swiss health care system
    Clara Thierfelder
    Swiss Centre for International Health, Swiss Tropical Institute
    Eur J Public Health 15:86-90. 2005
    ....
  61. ncbi Genetic evidence for the Mongolian ancestry of Kalmyks
    Ivan Nasidze
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Am J Phys Anthropol 128:846-54. 2005
    ..Genetic analyses of even recent, relatively well-documented migrations such as of the Kalmyks can therefore lead to new insights concerning such migrations...
  62. ncbi The demography of disability and the effects of immigrant history: older Asians in the United States
    Jan E Mutchler
    Gerontology Institute, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA
    Demography 44:251-63. 2007
    ..We conclude that in later life, immigrant status confers few disability advantages among the Asian population in the United States...
  63. ncbi The impact of immigration on tuberculosis rates in the United Kingdom compared with other European countries
    R L Gilbert
    Health Protection Agency Centre for Infections, London, UK
    Int J Tuberc Lung Dis 13:645-51. 2009
    ..To investigate whether trends in tuberculosis (TB) rates across Europe are linked to patterns of migration...
  64. doi "It is more than the issue of taking tablets": the interplay between migration policies and TB control in Sweden
    Asli Kulane
    Division of Global Health, Department of Public Health Sciences, Karolinska Institutet, Sweden
    Health Policy 97:26-31. 2010
    ..Tuberculosis is re-emerging as a critical public health concern in Sweden among the immigrants. The aim of this study was to explore the experiences of the Somali community of TB care in the Stockholm area...
  65. ncbi Is nasopharyngeal cancer really a "Cantonese cancer"?
    Joseph Tien Seng Wee
    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore 169610, Singapore
    Chin J Cancer 29:517-26. 2010
    ..All these populations have a high incidence of NPC. Very early contact between southern Chinese and peoples of East Africa and Arabia can also account for the intermediate incidence of NPC in these regions...
  66. pmc The impact of out-migration on the nursing workforce in Kenya
    Jessica M Gross
    Emory University Nurses Council of Kenya, Nairobi, Kenya
    Health Serv Res 46:1300-18. 2011
    ..To examine the impact of out-migration on Kenya's nursing workforce...
  67. doi European neolithization and ancient DNA: an assessment
    Marie France Deguilloux
    Paleogenetic Platform, UMR PACEA, Bordeaux University
    Evol Anthropol 21:24-37. 2012
    ..In light of information emerging from diverse disciplines, including recent paleogenetic studies, the most plausible model explaining the movement of Neolithic pioneer groups in central Europe is that of leapfrog migration...
  68. doi Emerging genetic patterns of the European Neolithic: perspectives from a late Neolithic Bell Beaker burial site in Germany
    Esther J Lee
    Graduate School Human Development in Landscapes, Christian Albrechts University of Kiel, Germany
    Am J Phys Anthropol 148:571-9. 2012
    ..Furthermore, our data, along with those from previous studies, indicate that modern U5-lineages may have received little, if any, contribution from the Mesolithic or Neolithic mitochondrial gene pool...
  69. ncbi Do immigrants have an increased prevalence of unhealthy behaviours and risk factors for coronary heart disease?
    Malin Gadd
    Center of Family Medicine, Karolinska Institutet, Huddinge, Sweden
    Eur J Cardiovasc Prev Rehabil 12:535-41. 2005
    ..The aim of this study was to investigate whether unhealthy behaviours and risk factors for coronary disease are more common in immigrants than in Swedish-born individuals...
  70. doi International migration and gestational diabetes mellitus: a systematic review of the literature and meta-analysis
    Anita J Gagnon
    School of Nursing, McGill University, Montreal, QC, Canada
    Paediatr Perinat Epidemiol 25:575-92. 2011
    ..Research using clear, specific migrant definitions, adjusting for relevant risk factors and including other aspects of migration experiences is needed to confirm and understand these findings...
  71. ncbi Disability pension among immigrants in Sweden
    Torun Osterberg
    Department of Social Work, University of Goteborg, Sweden
    Soc Sci Med 63:805-16. 2006
    ..Future research needs to address which possible causes are most important for policies to address...
  72. pmc Y-chromosome evidence suggests a common paternal heritage of Austro-Asiatic populations
    Vikrant Kumar
    Molecular Anthropology Group, Biological Anthropology Unit, Indian Statistical Institute, Hubsiguda, Hyderabad, India
    BMC Evol Biol 7:47. 2007
    ..Mundari, Khasi-Khmuic and Mon-Khmer, along with the previously published data on 214 relevant populations from Asia and Oceania...
  73. ncbi The impact of the refugee decision on the trajectory of PTSD, anxiety, and depressive symptoms among asylum seekers: a longitudinal study
    Derrick Silove
    School of Psychiatry, University of New South Wales and Centre for Population Mental Health Research, Sydney South West Area Health Service, Australia
    Am J Disaster Med 2:321-9. 2007
    ..To identify the direct impact of the refugee decision on psychiatric symptoms by adjusting for other variables, namely sociodemographic characteristics, past trauma, and ongoing postmigration stresses...
  74. doi News from the west: ancient DNA from a French megalithic burial chamber
    Marie France Deguilloux
    Universite Bordeaux 1, UMR 5199 PACEA, Laboratoire d Anthropologie des Populations du Passé, B8 Avenue des Facultés, Talence Cedex, France
    Am J Phys Anthropol 144:108-18. 2011
    ..Nevertheless, our results strengthen conclusions demonstrating genetic discontinuity between modern and ancient Europeans whether through migration, demographic or selection processes, or social practices...
  75. pmc Y-chromosome variation in Altaian Kazakhs reveals a common paternal gene pool for Kazakhs and the influence of Mongolian expansions
    Matthew C Dulik
    Department of Anthropology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e17548. 2011
    ..In addition, all of them showed evidence of genetic influence by the 13(th) century CE Mongol Empire. Ultimately, the social and cultural traditions of the Kazakhs shaped their current pattern of genetic variation...
  76. pmc Emergence of social cohesion in a model society of greedy, mobile individuals
    Carlos P Roca
    ETH Zurich, CH 8092 Zurich, Switzerland
    Proc Natl Acad Sci U S A 108:11370-4. 2011
    ..Our model is, therefore, expected to shed light on the long-standing problem of the emergence and stability of cooperative behavior...
  77. doi Evaluating microevolutionary models for the early settlement of the New World: the importance of recurrent gene flow with Asia
    Soledad de Azevedo
    Centro Nacional Patagónico, Consejo Nacional de Investigaciones Científicas y Técnicas Bvd Brown 2915 U9120ACD Puerto Madryn, Argentina
    Am J Phys Anthropol 146:539-52. 2011
    ..Our results suggest a better explanatory performance of the Recurrent Gene Flow model, and provide additional insights concerning affinities among Asian and Native American Circum-Arctic groups...
  78. pmc Mycobacterium tuberculosis transmission in a country with low tuberculosis incidence: role of immigration and HIV infection
    Lukas Fenner
    Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
    J Clin Microbiol 50:388-95. 2012
    ..Continued access to health services and clinical follow-up will be essential to control TB in this population...
  79. pmc Moving away from nasty encounters enhances cooperation in ecological prisoner's dilemma game
    Te Wu
    Center for Systems and Control, State Key Laboratory for Turbulence and Complex Systems, College of Engineering, Peking University, Beijing, China
    PLoS ONE 6:e27669. 2011
    ....
  80. pmc Estimating the burden of tuberculosis among foreign-born persons acquired prior to entering the U.S., 2005-2009
    Philip M Ricks
    Division of Tuberculosis Elimination, United States Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e27405. 2011
    ..Our study objectives were to estimate the proportion of foreign-born persons with TB due reactivation TB and to describe characteristics of foreign-born persons with reactivation TB...
  81. ncbi High prevalence of vitamin D deficiency in pregnant non-Western women in The Hague, Netherlands
    Irene M van der Meer
    Municipal Health Service of The Hague, The Hague, Netherlands
    Am J Clin Nutr 84:350-3; quiz 468-9. 2006
    ..Vitamin D deficiency is common in dark-skinned persons living in northern countries. Vitamin D deficiency during pregnancy may have serious consequences for both mother and child...
  82. doi The human genetic history of East Asia: weaving a complex tapestry
    Mark Stoneking
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D04103 Leipzig, Germany
    Curr Biol 20:R188-93. 2010
    ....
  83. ncbi Social determinants of health in Canada's immigrant population: results from the National Population Health Survey
    J R Dunn
    Centre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada
    Soc Sci Med 51:1573-93. 2000
    ..The complexity of immigrants' experiences, combined with the inherent limitations of cross-sectional survey data are discussed as major limitations to this kind of research...
  84. ncbi Migration and mental health
    D Bhugra
    HSRD, Institute of Psychiatry, De Crespigny Park, London SE5 5AF, UK
    Acta Psychiatr Scand 109:243-58. 2004
    ..The process of migration is not simple or straightforward. The aim of this review is to distil existing information on how migration influences individuals' mental state and how it determines help seeking as well as pathways to care...
  85. ncbi Mental health of Cambodian refugees 2 decades after resettlement in the United States
    Grant N Marshall
    RAND, Santa Monica, Calif 90407, USA
    JAMA 294:571-9. 2005
    ..Little is known about the long-term mental health of trauma-exposed refugees years after permanent resettlement in host countries...
  86. pmc Ancient DNA reveals male diffusion through the Neolithic Mediterranean route
    Marie Lacan
    Laboratoire d anthropologie moléculaire et imagerie de synthèse, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5288, 31073 Toulouse, France
    Proc Natl Acad Sci U S A 108:9788-91. 2011
    ....
  87. pmc Ethiopians and Khoisan share the deepest clades of the human Y-chromosome phylogeny
    Ornella Semino
    Dipartimento di Genetica e Microbiologia, Universita di Pavia, Pavia, Italy
    Am J Hum Genet 70:265-8. 2002
    ..The first observation confirms the ancestral affinity between the Ethiopians and the Khoisan, which has previously been suggested by both archaeological and genetic findings...
  88. ncbi Obesity, overweight and ethnicity
    Mark S Tremblay
    Health Statistics Division, Statistics Canada, Ottawa, Ontario, K1A 0T6
    Health Rep 16:23-34. 2005
    ..This article describes the prevalence of self-reported overweight and obesity, based on body mass index (BMI), by ethnicity and examines the influence of time since immigration within and between ethnic groups...
  89. pmc Brain drain from developing countries: how can brain drain be converted into wisdom gain?
    Sunita Dodani
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburg, 3512 Fifth Avenue, Room 313, Pittsburgh, PA 15101, USA
    J R Soc Med 98:487-91. 2005
    ....
  90. ncbi Hepatitis B knowledge and practices among Chinese immigrants to the United States
    Vicky M Taylor
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Asian Pac J Cancer Prev 7:313-7. 2006
    ..Chronic carriage of hepatitis B virus (HBV) is the most common underlying cause of liver cancer among Chinese Americans. Our objective was to describe Chinese immigrants' hepatitis B knowledge, testing, and vaccination levels...
  91. doi Monte Verde: seaweed, food, medicine, and the peopling of South America
    Tom D Dillehay
    Department of Anthropology, Vanderbilt University, Nashville, TN 37265, USA
    Science 320:784-6. 2008
    ..These data are consistent with the ideas that an early settlement of South America was along the Pacific coast and that seaweeds were important to the diet and health of early humans in the Americas...
  92. doi Imported malaria in adults and children: epidemiological and clinical characteristics of 380 consecutive cases observed in Verona, Italy
    Marta Mascarello
    Department of Infectious Diseases, University of Verona, Verona, Italy
    J Travel Med 15:229-36. 2008
    ....
  93. pmc Probing deeper into first American studies
    Tom D Dillehay
    Department of Anthropology, Vanderbilt University, Nashville, TN 37221, USA
    Proc Natl Acad Sci U S A 106:971-8. 2009
    ..Some approaches to fill voids in data, methods, and the broader conceptualization of the process also are considered...
  94. pmc The effect on cardiovascular risk factors of migration from rural to urban areas in Peru: PERU MIGRANT Study
    J Jaime Miranda
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    BMC Cardiovasc Disord 9:23. 2009
    ..Thus the Peruvian context offers a unique opportunity to test the effects of migration...
  95. doi Imported malaria in immigrants to Italy: a changing pattern observed in north eastern Italy
    Marta Mascarello
    Department of Infectious Diseases, University of Verona, Verona, Italy
    J Travel Med 16:317-21. 2009
    ..Nevertheless, premunition could be progressively lost after a long period of nonexposure. We investigated the changing pattern of malaria in immigrants in two definite 5-year periods one decade apart...
  96. pmc Imported malaria in an area in southern Madrid, 2005-2008
    Sonia Rey
    Microbiology and Parasitology Department, Severo Ochoa University Hospital, Avda Orellana s n, Leganes, Madrid, Spain
    Malar J 9:290. 2010
    ..The objective of this work was to describe the malaria cases diagnosed at the Severo Ochoa University Hospital (HUSO) in Leganés in the south of the Madrid Region from 2005 to 2008...
  97. pmc Hospital emergency department utilisation rates among the immigrant population in Barcelona, Spain
    Andrea Buron
    Health Services Evaluation and Clinical Epidemiology Department, IMIM Hospital del Mar, Barcelona, Spain
    BMC Health Serv Res 8:51. 2008
    ..However, utilisation rates in our environment have not yet been studied. We aimed to compare emergency department utilisation rates between Spanish-born and foreign-born residents in a public hospital of Barcelona...
  98. ncbi Traces of human migrations in Helicobacter pylori populations
    Daniel Falush
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, 10117 Berlin, Germany
    Science 299:1582-5. 2003
    ..Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the slave trade...
  99. ncbi Measuring culture: a critical review of acculturation and health in Asian immigrant populations
    Talya Salant
    Committee on the History of Culture and The Pritzker School of Medicine, The University of Chicago, Chicago, IL 60637, USA
    Soc Sci Med 57:71-90. 2003
    ..The critical review thus provides insights into the diverse ways that the relationship between culture and health is measured in this complicated and growing literature...
  100. ncbi Effects of purifying and adaptive selection on regional variation in human mtDNA
    Eduardo Ruiz-Pesini
    Center for Molecular and Mitochondrial Medicine and Genetics, University of California, Irvine, CA 92697 3940, USA
    Science 303:223-6. 2004
    ..Thus, specific mtDNA replacement mutations permitted our ancestors to adapt to more northern climates, and these same variants are influencing our health today...
  101. pmc The dual origin of the Malagasy in Island Southeast Asia and East Africa: evidence from maternal and paternal lineages
    Matthew E Hurles
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
    Am J Hum Genet 76:894-901. 2005
    ..As a result of their equally balanced admixed ancestry, the Malagasy may represent an ideal population in which to identify loci underlying complex traits of both anthropological and medical interest...

Research Grants81

  1. Effects of Methylmercury on Neuronal Cell Migration
    Hitoshi Komuro; Fiscal Year: 2010
    ..Answers to the questions raised in this project will provide insights for development of therapies that counter MeHg-induced brain malformation. ..
  2. Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex
    Derek Toomre; Fiscal Year: 2009
    ..Consistent with the recovery act's goal, this funding will provide full-time summer employment for 4 undergraduate students and accelerate scientific achievement of the parent DP2 award...
  3. Prevention of Complications in Thalassemia
    Elliott P Vichinsky; Fiscal Year: 2011
    ..Ourmissionalsoincludesmonitorinbgloodsafety amongtransfusion-dependtehnatlassemipaatientsa,ndprovidingoutreachand educationservicestoallat-riskpopulationtshroughoutht estate. ..
  4. Yasmin Wadia; Fiscal Year: 2014
    ..Fibro-optic capable: Minimally invasive laparoscopic &robotic applications. ..
  5. Mice Humanized with Hepatocytes and iPS Cells from Patients with Metabolic Diseas
    Stephen C Strom; Fiscal Year: 2010
    ..We propose these humanized mice will be a technology platform to better understand the human disease and it will aid in the development of gene or cellular therapy to correct these devastating diseases. ..
  6. Human embryonic stem cell-derived neural crest stem cells and Hirschsprung disea
    Sean J Morrison; Fiscal Year: 2010
    ..These studies will test whether NCSCs with specific regional characteristics can be derived from hES cells and whether these cells engraft in the gut of an animal model of Hirschsprung disease. ..
  7. Tibor T Glant; Fiscal Year: 2016
    ....
  8. Ligand Directed Transdermal siRNA Delivery to Improve Wound Healing
    David M Evans; Fiscal Year: 2012
    ..The outcome of this project will be the initial characterization of a valuable therapeutic option for treatment of patients with various types of skin wounds. ..
  9. FASEB SRC on Lysophospholipd Mediators in Health and Disease
    Julie D Saba; Fiscal Year: 2011
    ....
  10. CRF-Oxytocin Interaction in the Regulation of Stress and Affect
    Joanna Dabrowska; Fiscal Year: 2013
    ..My career objective is to conduct independent research to understand how stress and affect interact and elucidate their respective roles in the etiology of mental disorders like depression and anxiety. ..
  11. NICOLE RENEE TARTAGLIA; Fiscal Year: 2015
    ....
  12. Regulation of B Cell Function by Membrane-Cytoskeletal Remodeling
    Neetu Gupta; Fiscal Year: 2012
    ..Lessons learnt from understanding the role of ezrin in B cell function can be applied towards therapeutic design for B cell-dependent human diseases. ..
  13. Priyabrata Mukherjee; Fiscal Year: 2016
    ....
  14. Stephen E McGowan; Fiscal Year: 2016
    ..These studies are relevant to other vascular diseases including stroke, diabetes, and chronic renal insufficiency, which are also common among veterans. ..
  15. Inhibition of human neutrophil function by Francisella tularensis
    Lee Ann H Allen; Fiscal Year: 2012
    ..The results of this study may lead to new treatments to combat this severe and often fatal lung infection. ..
  16. Craig T Morita; Fiscal Year: 2016
    ....
  17. Enterococcus faecalis, Colorectal Cancer, and Bystander Effects
    Mark M Huycke; Fiscal Year: 2012
    ..These results will identify new approaches and targets for preventing sporadic colorectal cancer. ..
  18. Norma S Kenyon; Fiscal Year: 2015
    ..Furthermore, MSC administration may constitute a safe and effective way to reverse rejection episodes. ..
  19. Role of IKK in NSCLC: Modulation of SMRT and NF-kappaB
    Marty W Mayo; Fiscal Year: 2012
    ..The overall goal of this project is use these newly identified gene products as novel therapeutic targets for detection and treatment of NSCLC. ..
  20. Rajvir Dahiya; Fiscal Year: 2015
    ..Since the goal of this proposal is to investigate the dietary mediated inhibition of RCC through activation of tumor suppressor miRNAs, we believe that the work proposed is highly relevant to Veterans health and the VA mission. ..
  21. Junxuan Lu; Fiscal Year: 2014
    ..These multiple targeting activities plus published work supporting anti- angiogenesis activity provide strong rationale for testing the efficacy of PGG for prostate cancer chemoprevention. ..
  22. Maria Diakonova; Fiscal Year: 2014
    ..Understanding how these proteins work together will help to design new therapeutic approaches and possibly drugs for treatment of different human diseases and breast cancer. ..
  23. SAMY LEWIZ HABIB; Fiscal Year: 2016
    ....
  24. Xianglin Shi; Fiscal Year: 2015
    ..Present study attempts to identify cyanidin-3-glucoside, a plant-derived compound, as a mechanism-based preventive agent against UV-induced skin cancers. ..
  25. Maternal obesity depresses essential fatty acid transport in the placenta
    PERRIE F O'TIERNEY-GINN; Fiscal Year: 2012
    ..The proposed studies will help us understand how obesity during pregnancy alters the placental transfer of nutrients from mother to child and how this impacts neonatal nutrition. ..
  26. PAUL CAMILLE TUMEH; Fiscal Year: 2015
    ..As a future independent investigator, this system will enable me to collaborate with scientists and clinicians to address a wide scope of challenges in medicine. ..
  27. Mitzi Nagarkatti; Fiscal Year: 2015
    ..abstract_text> ..
  28. ANDREW GREGORY SIKORA; Fiscal Year: 2015
    ..abstract_text> ..
  29. Analyzer for Monitoring Personal Environmental Exposure to Fluids and Materials
    MATTHEW CUSACK; Fiscal Year: 2010
    ..Other applications for this technology are expected to be part of the GEI, the National Children's Study (NCS), in workplace assessments of occupational exposure, hospitals, or other medical or research settings. ..
  30. Mary K Sheats; Fiscal Year: 2016
    ....
  31. James B Martins; Fiscal Year: 2014
    ..Similarly such drugs may be combined with other antioxidants to prevent dangerous heart rhythms. ..
  32. Brian F Volkman; Fiscal Year: 2016
    ..New inhibitors and variants of SDF developed in this project will likely find application as diagnostic and therapeutic agents in a wide range of human diseases, including cardiovascular disease, cancer and multiple sclerosis. ..
  33. Perrie F O'Tierney-Ginn; Fiscal Year: 2015
    ..abstract_text> ..
  34. Beverley Greenwood-Van Meerveld; Fiscal Year: 2016
    ..Moreover, we will examine whether rats exposed to ELS show altered behavioral responses to chronic stress in adulthood compared to age-matched controls ..
  35. Nitric Oxide in Hemodialysis AV Fistula Maturation
    Richard A Cohen; Fiscal Year: 2010
    ....
  36. Small Molecule targeting of NADPH oxidase in neutrophils
    Marie Dominique Filippi; Fiscal Year: 2010
    ..Therefore, our study will help delivering a novel pharmaceutical target, and suitable lead compounds for the treatment of lung inflammation, such as ALI and ARDS. ..
  37. Environmental Risk Factors for Copy Number Variation in Human Chromosomes
    THOMAS EDWARD WILSON; Fiscal Year: 2010
    ....
  38. Tumor Microenvironment Interactions in Brain Tumors
    Eric C Holland; Fiscal Year: 2010
    ..abstract_text> ..
  39. Integrated signaling of eicosanoids in HSC formation and regeneration
    Trista E North; Fiscal Year: 2013
    ..These results are expected to reveal deeper insight into interactive roles of inflammatory mediators in marrow regeneration and have relevance for combinatorial targeting to direct clinical outcome in transfusion biology. ..
  40. The Role of Decidual Innate Immunity in the Pathogenesis of Preeclampsia
    Se Te Joseph Huang; Fiscal Year: 2012
    ..This study of the immunological basis of preeclampsia will result in new therapies to combat this complication during pregnancy. Hence, the welfare of affected families and society will be considerably improved. ..
  41. Air Pollution on Adiposity and Vascular Dysfunction: White or Brown Matters?
    Qinghua Sun; Fiscal Year: 2010
    ..abstract_text> ..
  42. Nuclear-Cytoplasmic Shuttling of Foxc2 via 14-3-3 Determines Proximal Tubule Cell
    DIANA LYNNE GOLDEN; Fiscal Year: 2012
    ..Extensive examination of the mechanisms and potential therapeutic targets will advance the understanding and potential cure for AKI in proximal tubular regeneration. ..
  43. FASEB SUMMER CONFERENCE ON PHOSPHOLIPASES
    Alex Brown; Fiscal Year: 2010
    ..The funds requested in this proposal will make an invaluable contribution to the support of this conference and in particular the development of young investigators. ..
  44. Howard B Lieberman; Fiscal Year: 2016
    ....
  45. Huaizhu Wu; Fiscal Year: 2016
    ..This study has the potential to provide novel preventive and therapeutic targets for obesity-related atherosclerosis and diabetes. ..
  46. Anisa Shaker; Fiscal Year: 2016
    ..These studies may provide the basis for novel therapeutic approaches to inflammatory bowel disease and CAC. ..
  47. Novel Macrolide Th17 Inhibitors
    Jay K Kolls; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: Interleukin-17 can cause lung inflammation and asthma. This project is to indentify drugs that can inhibit IL-17 and lung inflammation. ..
  48. TAMARA G TERZIAN; Fiscal Year: 2016
    ....
  49. RSK-2 regulates integrin-mediated adhesion and migration
    JOE WILLIAM RAMOS; Fiscal Year: 2013
    ..This will determine if these proteins are suitable targets for the development of new adhesion specific disease therapies. In particular we will test if RSK2 can serve as a potential new therapeutic target in glioma. ..
  50. PEARLIE K BURNETTE; Fiscal Year: 2016
    ..Additionally, the efficacy of pharmacological inhibitors to block homing to the bone marrow will be tested to provide critical pre-clinical data for application to clinical studies in patients in the future. ..
  51. Christin Carter-Su; Fiscal Year: 2016
    ....
  52. Mucosal Memory T Cells at the Vanguard of Human Host Defense
    Donna L Farber; Fiscal Year: 2010
    ....
  53. Cholesterol and Lymphatic Transport of Molecules and Cells
    Melody A Swartz; Fiscal Year: 2012
    ..Several promising tools that may ultimately lead to valuable insight into how lymphatic disorders could be treated will be explored in this proposal. ..
  54. A novel telomerase expressing lung fibroblast phenotype
    Sem H Phan; Fiscal Year: 2012
    ..It is hoped that attainment of the study's objectives will provide new ideas for effective treatment and management of these diseases. ..
  55. Modeling TH17 Cells in Acute GVHD
    JONATHAN STUART SERODY; Fiscal Year: 2010
    ..This work has the capacity to fundamentally alter our perceptions of the biology of GVHD and offer new avenues for therapy. ..
  56. Osteoclastic Protein-Tyrosine Phosphatase and Resorption
    Kin Hing William Lau; Fiscal Year: 2013
    ..This project may allow disclose novel targets for development of more effective anti-resorptive therapies for osteoporosis and related disease. Thus, this project is highly relevant to the VA patient care mission. ..
  57. Mechanism of Irradiation Pulmonary Fibrosis
    Joel S Greenberger; Fiscal Year: 2012
    ..Project Narrative This irradiation application addresses a critical problem in managing the side effects of thoracic radiotherapy for lung and esophagus cancer. ..
  58. Ameae M Walker; Fiscal Year: 2015
    ..Results may also lead to the development of procedures for safely enhancing immunity in children. ..
  59. Jeanette Gowen Cook; Fiscal Year: 2016
    ....
  60. Neuropilin and semaphorin, anti-angiogenesis activities and mechanisms
    Michael Klagsbrun; Fiscal Year: 2009
    ..abstract_text> ..
  61. Glycosaminoglycans and Cell Traffic in the Lymphatic Microenvironment
    Mark M Fuster; Fiscal Year: 2012
    ..This work may lead to novel therapy to inhibit the spread, morbidity, and mortality of cancer in our Veteran population. ..
  62. CLIFFORD JAMES ROSEN; Fiscal Year: 2015
    ..Importantly, these studies will shed new light on the ErbB and Dock7 signaling pathways in bone and in BAT. Defining shared metabolic-skeletal networks may lead to new treatments for age-related osteoporosis. ..
  63. Controlled delivery of polypeptide hormone calcitonin
    Jagdish Singh; Fiscal Year: 2013
    ..Development of such a novel therapeutic system is critical for successful treatment of bone diseases, especially osteoporosis in men and postmenopausal women, in order to improve patient quality of life. ..
  64. GARY ANDREW WEISMAN; Fiscal Year: 2016
    ..abstract_text> ..
  65. Polarization and directed cell movements in engineered cellular environments
    Deborah E Leckband; Fiscal Year: 2010
    ....
  66. NOVEL FACTORS THAT REGULATE GNRH NEURONAL DEVELOPMENT
    Margaret E Wierman; Fiscal Year: 2010
    ....
  67. Gene Networks in Neural Crest-derived Innervation of the Lower Urinary Tract
    E MICHELLE MICHELLE SOUTHARD SMITH; Fiscal Year: 2010
    ..This proposal is in response to the broad Challenge grant area of Regenerative medicine and meets multiple needs for basic research in development lower urinary tract innervation. ..
  68. A Validated Resource of Thyroid Cancer Cell Lines for Pathway Discovery
    JEFFREY ALLEN KNAUF; Fiscal Year: 2010
    ....
  69. T Cells in the Pathogenesis of Systemic Sclerosis
    Chris Platsoucas; Fiscal Year: 2005
    ..d. To identify Thl, Th2, suppressor, anergic and CTL T-cell clones from those developed above, on the basis of expression patterns of their genes, using DNA array technology. ..
  70. ENGINEERING INTEGRIN--MEDIATED CELL MIGRATION
    Douglas Lauffenburger; Fiscal Year: 2002
    ..The knowledge gained from these studies may help to control the cell migration in tissue engineering applications. ..
  71. Understanding the Rise of Obesity among Immigrants: A Pilot Study
    Gilbert Gee; Fiscal Year: 2010
    ..The identification of factors that contribute to weight gain among immigrants may provide key information for the development of primary prevention programs. ..
  72. Stability of Mexican-Origin Extended Family Households
    Jennifer Van Hook; Fiscal Year: 2005
    ..abstract_text> ..
  73. IMMIGRANTS AND THEIR TRANSITION TO A NEW LABOR MARKET
    ZVI ECKSTEIN; Fiscal Year: 1999
    ..The sheer size of the current immigration wave and the high concentration in high skilled occupation enable macroeconomic effects to be identified. ..
  74. MOLECULAR MECHANISMS OF NEURONAL CELL MIGRATION
    Richard Cameron; Fiscal Year: 2000
    ....
  75. Effects of Insulin on VSM Migration
    Andrew Kahn; Fiscal Year: 2004
    ..These studies will determine the mechanism for insulin's inhibition of VSMC migration and help explain the link between enhanced atherosclerosis/restenosis and insulin resistance. ..
  76. NEUTROPHILS TRANSENDOTHELIAL MIGRATION: MOLECULAR EVENTS
    Alan Burns; Fiscal Year: 2004
    ..The proposed research will provide new data and insights for the design of anti-inflammatory therapies that target the multistep process of leukocyte migration. ..