Genomes and Genes
Summary: Behavioral response associated with the achieving of gratification.
Publications217 found, 100 shown here
- Gastrointestinal regulation of food intakeDavid E Cummings
Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98108, USA
J Clin Invest 117:13-23. 2007..The increasingly nuanced understanding of the mechanisms mediating gut-peptide regulation and action provides promising targets for new strategies to combat obesity and diabetes...
- Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a mealPatrice D Cani
Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Universite Catholique de Louvain, Brussels, Belgium
Am J Clin Nutr 90:1236-43. 2009..In rodents, these effects are associated with an increase in plasma gut peptide concentrations, which are involved in appetite regulation and glucose homeostasis...
- Images of desire: food-craving activation during fMRIMarcia Levin Pelchat
Monell Chemical Senses Center, Philadelphia, PA 19104 3308, USA
Neuroimage 23:1486-93. 2004..Craving-related changes in fMRI signal were identified in the hippocampus, insula, and caudate, three areas reported to be involved in drug craving. Thus, this work supports the common substrate hypothesis for food and drug cravings...
- Critical role for peptide YY in protein-mediated satiation and body-weight regulationRachel L Batterham
Centre for Diabetes and Endocrinology, Department of Medicine, University College London, WC1E 6JJ, United Kingdom
Cell Metab 4:223-33. 2006..Our findings suggest that modulating the release of endogenous satiety factors, such as PYY, through alteration of specific diet constituents could provide a rational therapy for obesity...
- The timing of mealsJan H Strubbe
Department of Neuroendocrinology, University of Groningen, Haren, The Netherlands
Psychol Rev 111:128-41. 2004..The third relates to the size of the preceding meal, such that larger meals cause a longer delay until the onset of the next meal. Superimposed on these 3 are factors related to learning, convenience, and opportunity...
- Dietary fiber supplements: effects in obesity and metabolic syndrome and relationship to gastrointestinal functionsAthanasios Papathanasopoulos
Clinical Enteric Neuroscience Translational and Epidemiological Research, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Gastroenterology 138:65-72.e1-2. 2010....
- Does hunger and satiety drive eating anymore? Increasing eating occasions and decreasing time between eating occasions in the United StatesBarry M Popkin
Carolina Population Center, University of North Carolina, 123 West Franklin Street, Chapel Hill, NC 27516, USA
Am J Clin Nutr 91:1342-7. 2010..The design of dietary, metabolic, and intervention studies should reflect the meal patterning of free-living individuals, but this design has not been systematically reviewed recently...
- Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA-cp ratsJill A Parnell
Department of Physical Education and Recreation Studies, Mount Royal University, 4825 Mount Royal Gate SW, Calgary, AB, Canada
Br J Nutr 107:601-13. 2012..The combined effects of prebiotics may have therapeutic potential for obesity...
- Gastric distention activates satiety circuitry in the human brainGene Jack Wang
Brookhaven National Laboratory, Upton, NY 11973, USA
Neuroimage 39:1824-31. 2008..These findings provide evidence that the left amygdala and insula process interoceptive signals of fullness produced by gastric distention involved in the controls of food intake...
- The effect of fruit in different forms on energy intake and satiety at a mealJulie E Flood-Obbagy
Department of Nutritional Sciences, The Pennsylvania State University, 226 Henderson Building, University Park, PA 16802, USA
Appetite 52:416-22. 2009..Adding naturally occurring levels of fiber to juice did not enhance satiety. These results suggest that solid fruit affects satiety more than pureed fruit or juice, and that eating fruit at the start of a meal can reduce energy intake...
- The effects of high protein diets on thermogenesis, satiety and weight loss: a critical reviewThomas L Halton
Dept of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
J Am Coll Nutr 23:373-85. 2004..Although recent evidence supports potential benefit, rigorous longer-term studies are needed to investigate the effects of high protein diets on weight loss and weight maintenance...
- Salad and satiety: energy density and portion size of a first-course salad affect energy intake at lunchBarbara J Rolls
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA
J Am Diet Assoc 104:1570-6. 2004..We tested the effect on meal intake of varying the energy density and portion size of a compulsory first-course salad...
- Effect of television viewing at mealtime on food intake after a glucose preload in boysNick Bellissimo
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 3E2, Canada
Pediatr Res 61:745-9. 2007..In conclusion, TVV while eating a meal contributes to increased energy intake by delaying normal mealtime satiation and reducing satiety signals from previously consumed foods...
- Characterization of the diurnal rhythm of peptide YY and its association with energy balance parameters in normal-weight premenopausal womenBrenna R Hill
Women s Health and Exercise Laboratory and the Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
Am J Physiol Endocrinol Metab 301:E409-15. 2011..Thus, PYY varies in accordance with energy content and RMR, supporting a role for PYY in energy balance modulation...
- Appetite regulation and energy balanceCharlotte Erlanson-Albertsson
Department of Experimental Medicine, University of Lund, Lund, Sweden
Acta Paediatr Suppl 94:40-1. 2005..The palatable food works by weakening the satiety signals and activating the hunger signals. The reward system with endogenous opiates may also be activated...
- Food form and portion size affect postprandial appetite sensations and hormonal responses in healthy, nonobese, older adultsHeather J Leidy
Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, Kansas, USA
Obesity (Silver Spring) 18:293-9. 2010..larger portions suggest that appetite control is influenced by food form and portion size in older adults. These findings may enhance the development of appropriate dietary strategies that help to regulate energy balance...
- Operant self-stimulation of dopamine neurons in the substantia nigraMark A Rossi
Department of Psychology and Neuroscience, Duke University, Durham, North Carolina, United States of America
PLoS ONE 8:e65799. 2013..Together these results suggest that selective activation of SNC DA neurons can be sufficient for acquisition and maintenance of a new instrumental action...
- Signals that influence food intake and body weightStephen C Woods
Department of Psychiatry, University of Cincinnati, 2170 East Galbraith Road, Cincinnati, OH 45237, United States
Physiol Behav 86:709-16. 2005..This review discusses hormonal and related satiety signals generated as food is being consumed, and upon adiposity signals related to the amount of fat stored in the body, that influence energy intake and ultimately body weight...
- Cholinergic regulation of ghrelin and peptide YY release may be impaired in obesityChristina Maier
Clinical Division of Endocrinology and Metabolism, Department ofMedicine III, Medical University of Vienna, Vienna, Austria
Diabetes 57:2332-40. 2008..The aim of this study was to examine the effects of the cholinergic antagonist atropine on ghrelin, PYY, glucose, and insulin under basal conditions and after meal ingestion in lean and obese subjects...
- Measuring 'expected satiety' in a range of common foods using a method of constant stimuliJeffrey M Brunstrom
Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol, England, United Kingdom
Appetite 51:604-14. 2008..Future use of this methodology is discussed, both in relation to our understanding of portion-size decisions and its application more generally...
- Sweetness, satiation, and satietyFrance Bellisle
Centre de Recherche en Nutrition Humaine d Ile de France, Universite Paris, Bobigny, France
J Nutr 142:1149S-54S. 2012..The brain mechanisms of food reward (in terms of "liking" and "wanting") are also addressed. Finally, we highlight the importance of reward homeostasis, which can help prevent eating in the absence of hunger, for the control of intake...
- Loss of acute satiety response to cholecystokinin in pregnant ratsS R Ladyman
Centre for Neuroendocrinology and Department of Anatomy, University of Otago, Dunedin, New Zealand
J Neuroendocrinol 23:1091-8. 2011..These results indicate that pregnant rats are no longer responsive to the actions of CCK on short-term food intake and that CCK action in the NTS is reduced during pregnancy...
- Impact of acute sleep restriction on cortisol and leptin levels in young womenAntonina Omisade
Department of Psychology, Dalhousie University, Halifax, NS, Canada
Physiol Behav 99:651-6. 2010..04). Hunger and craving scores did not differ significantly between days. A single night of restricted sleep affected cortisol rhythms and morning leptin levels in young women...
- Dietary variety, energy regulation, and obesityH A Raynor
Department of Psychology, University at Buffalo, New York 14214, USA
Psychol Bull 127:325-41. 2001....
- Augmented reinforcer value and accelerated habit formation after repeated amphetamine treatmentR E Nordquist
Department of Anatomy and Neurosciences, Research Institute of Neurosciences, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Eur Neuropsychopharmacol 17:532-40. 2007..These data show that both habit formation and motivational value of reinforcers are augmented in amphetamine-sensitized rats, and suggest that the task demands determine which behavioral alteration is most prominently expressed...
- Norepinephrine and the control of food intakeP J Wellman
Department of Psychology, Texas A and M University, College Station, Texas 77843 4235, USA
Nutrition 16:837-42. 2000..The present review considers potential interactions of NE with substances such as leptin and neuropeptide Y that alter eating...
- Fat as a risk factor for overconsumption: satiation, satiety, and patterns of eatingJ E Blundell
Department of Psychology, University of Leeds, United Kingdom
J Am Diet Assoc 97:S63-9. 1997..A first stage in a health program should be to prevent passive overconsumption...
- The glucose-dependent insulinotropic polypeptide and glucose-stimulated insulin response to exercise training and diet in obesityKaren R Kelly
Department of Pathobiology, Lerner Research Institute, Cleveland, OH 44195, USA
Am J Physiol Endocrinol Metab 296:E1269-74. 2009....
- Attenuated peptide YY release in obese subjects is associated with reduced satietyC W le Roux
Department of Metabolic Medicine, 6th Floor Commonwealth Building, Hammersmith Hospital, Imperial College London, London W12 0NN, United Kingdom
Endocrinology 147:3-8. 2006..We conclude that obese subjects have a PYY deficiency that would reduce satiety and could thus reinforce their obesity...
- Recall of recent lunch and its effect on subsequent snack intakeSuzanne Higgs
School of Psychology, University of Birmingham, England, UK
Physiol Behav 94:454-62. 2008..It is concluded that the inhibitory effect of recalling foods eaten at lunch on subsequent snack intake is a robust phenomenon that is related to memory of that lunch and is moderated by tendency toward dietary disinhibition...
- Hunger selectively modulates corticolimbic activation to food stimuli in humansK S LaBar
Department of Psychology Experimental, Duke University, Durham, North Carolina 27708 0999, USA
Behav Neurosci 115:493-500. 2001..These results support the hypothesis that the amygdala and associated inferotemporal regions are involved in the integration of subjective interoceptive states with relevant sensory cues processed along the ventral visual stream...
- Energy density of foods: effects on energy intakeJ Stubbs
The Rowett Research Institute, Bucksburn, Aberdeen, UK
Crit Rev Food Sci Nutr 40:481-515. 2000..The available evidence suggests that we should be evolving more complex, multifactor models to account for the observations that both macronutrients and ED affect EI rather than substituting one simplistic model with another...
- Beverage viscosity is inversely related to postprandial hunger in humansR D Mattes
Department of Foods and Nutrition, Purdue University, Room 212, 1264 Stone Hall, West Lafayette, IN 47907 1264, USA
Physiol Behav 74:551-7. 2001..No significant differences were noted in the size or time to first meal or 24 h energy intake. These data indicate viscosity exerts an independent inverse effect on hunger in humans...
- The cholecystokinin type A receptor g.179A>G polymorphism affects feeding rateR D Houston
Division of Genetics and Genomics, Roslin Institute Edinburgh, Roslin, Midlothian EH25 9PS, UK
Anim Genet 39:187-8. 2008..The data indicate that the daily feed intake increasing effect of the DQ496228:g.179G allele is mediated through a faster rate of feed intake, without evidence for an effect on other feeding behaviour traits...
- Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety responseN M Avena
Department of Psychology, Princeton University, Princeton, NJ 08540, USA
Neuroscience 139:813-20. 2006....
- Development and preliminary validation of a silhouette satiety scale for childrenMyles S Faith
Obesity Research Center, Columbia University College of Physicians and Surgeons, 1090 Amsterdam Avenue 14A, New York, NY 10025, USA
Physiol Behav 76:173-8. 2002..Young children may be more capable of quantitatively reporting feelings of satiety than is commonly believed, if appropriate experimental materials are used...
- Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36P T Pfluger
Department of Psychiatry, University of Cincinnati, Office E 217, Genome Research Institute, 2170 East Galbraith Road, Cincinnati, Ohio 45237, USA
J Clin Endocrinol Metab 92:583-8. 2007..Although the pharmacological value of PYY is controversial, further study of the secretion of the precursor PYY(1-36) and the pharmacologically active PYY(3-36) is indicated to determine the potential role in energy balance regulation...
- Measuring meals: structure of prandial food and water intake of ratsEric P Zorrilla
Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
Am J Physiol Regul Integr Comp Physiol 288:R1450-67. 2005..Thus log-survivorship analysis is not appropriate for identifying meal breakpoints, and the consideration of drinking in meal definitions can provide a better estimate of meal structure...
- Short-term sleep loss decreases physical activity under free-living conditions but does not increase food intake under time-deprived laboratory conditions in healthy menSebastian M Schmid
Departments of Internal Medicine I, the University of Luebeck, Luebeck, Germany
Am J Clin Nutr 90:1476-82. 2009..Short sleep duration is correlated with an increased risk of developing obesity and cardiovascular disease, but the mechanisms behind this relation are largely unknown...
- Gastrointestinal satiety signals I. An overview of gastrointestinal signals that influence food intakeStephen C Woods
Dept of Psychiatry, Univ of Cincinnati, Cincinnati, OH 45267, USA
Am J Physiol Gastrointest Liver Physiol 286:G7-13. 2004..Most factors that influence how much food is eaten during individual meals act by changing the sensitivity to satiety signals. This includes adiposity signals as well as habits and learning, the social situation, and stressors...
- Evidence that paraventricular nucleus oxytocin neurons link hypothalamic leptin action to caudal brain stem nuclei controlling meal sizeJames E Blevins
VA Puget Sound Health Care System, Research Service 151 1660 S Columbian Wy, Seattle, WA 98108, USA
Am J Physiol Regul Integr Comp Physiol 287:R87-96. 2004....
- Water incorporated into a food but not served with a food decreases energy intake in lean womenB J Rolls
Nutrition Department, The Pennsylvania State University, University Park 16802 6501, USA
Am J Clin Nutr 70:448-55. 1999..Previous research showed that decreasing the energy density (kJ/g) of foods by adding water to them can lead to reductions in energy intake. Few studies have examined how water consumed as a beverage affects food intake...
- Differential effects of gastric bypass and banding on circulating gut hormone and leptin levelsJudith Korner
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Obesity (Silver Spring) 14:1553-61. 2006..To quantify plasma concentrations of hormones that regulate energy homeostasis in order to establish possible mechanisms for greater weight loss after Roux-en-Y gastric bypass (RYGBP) compared with gastric banding (BND)...
- Olfactory sensory-specific satiety in humansE T Rolls
Department of Experimental Psychology, University of Oxford, UK
Physiol Behav 61:461-73. 1997..The implications for the control of food intake, and the way in which the brain computes sensory-specific satiety, are considered...
- Interactions between gastric emptying and satiety, with special reference to glucagon-like peptide-1P M Hellstrom
Department of Internal Medicine, Unit of Gastroenterology Karolinska Hospital, Karolinska Institutet, SE 171 76, Stockholm, Sweden
Physiol Behav 74:735-41. 2001..To conclude, after food intake, gut peptides may act in concert as neurohormonal satiety signals acting directly in the brain or indirectly via the vagus nerve, as well as through gastric sensory mechanisms to limit food intake...
- Effect of meal viscosity and nutrients on satiety, intragastric dilution, and emptying assessed by MRIL Marciani
Magnetic Resonance Centre, School of Physics and Astronomy, Nottingham NG7 2RD, United Kingdom
Am J Physiol Gastrointest Liver Physiol 280:G1227-33. 2001..96). Fullness was higher for high- compared with low-viscosity meals (P < 0.02), and with the nutrient meals this was associated with greater antral volumes (P < 0.05)...
- Effects of glucagon-like peptide-1(7-36)amide on motility and sensation of the proximal stomach in humansJ Schirra
Department of Gastroenterology and Endocrinology, Philipps University, Marburg, Germany
Gut 50:341-8. 2002..Glucagon-like peptide-1(7-36)amide (GLP-1) retards gastric emptying, reduces food intake, and inhibits antroduodenal and stimulates pyloric motility...
- The significance of protein in food intake and body weight regulationMargriet S Westerterp-Plantenga
Department of Human Biology, PO Box 616, 6200 MD Maastricht, The Netherlands
Curr Opin Clin Nutr Metab Care 6:635-8. 2003..To highlight the underexposed but important role of protein in food intake and body weight regulation...
- Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjectsE Ostman
Applied Nutrition and Food Chemistry, Department of Food Technology, Engineering and Nutrition, Lund University, Lund, Sweden
Eur J Clin Nutr 59:983-8. 2005..To investigate the potential of acetic acid supplementation as a means of lowering the glycaemic index (GI) of a bread meal, and to evaluate the possible dose-response effect on postprandial glycaemia, insulinaemia and satiety...
- Functional dyspepsia symptoms, gastric emptying and satiety provocative test: analysis of relationshipsR Cuomo
Dipartimento di Medicina Clinica e Sperimentale, Universita degli Studi di Napoli Federico II, Italy
Scand J Gastroenterol 36:1030-6. 2001....
- Gut hormones and appetite controlA M Wren
Department of Metabolic Medicine, Imperial College London, London, England
Gastroenterology 132:2116-30. 2007..Gut hormone-based therapies may thus provide an effective and well-tolerated treatment for obesity...
- Increasing the volume of a food by incorporating air affects satiety in menB J Rolls
Nutrition Department, The Pennsylvania State University, University Park 16802 6501, USA
Am J Clin Nutr 72:361-8. 2000..However, the addition of water affects not only the volume but also the energy density (kJ/g) of foods. No studies have examined the effect of volume independent of energy density on intake...
- The oxytocin/vasopressin receptor antagonist atosiban delays the gastric emptying of a semisolid meal compared to saline in humanBodil Ohlsson
Department of Clinical Sciences, Entrance 35, S 205 02 Malmo, Sweden
BMC Gastroenterol 6:11. 2006..Further, mRNA for oxytocin and its receptor have been found throughout the gastrointestinal (GI) tract. The aim of this study was therefore to examine whether oxytocin, or the receptor antagonist atosiban, influence the gastric emptying...
- Proteins and satiety: implications for weight managementStijn Soenen
Department of Human Biology, NUTRIM, Maastricht University, Maastricht, The Netherlands
Curr Opin Clin Nutr Metab Care 11:747-51. 2008..To highlight the satiating background and effects of proteins and their implications for weight management...
- Physical state of meal affects gastric emptying, cholecystokinin release and satietyA Santangelo
Department of Food Science and Technology, University of Milan, Italy
Br J Nutr 80:521-7. 1998..Moreover, the relationship observed between antral area and fullness sensation confirms that antral distension plays a part in the regulation of eating behaviour...
- Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin systemWei Fan
Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
Nat Neurosci 7:335-6. 2004....
- The role of oxyntomodulin and peptide tyrosine-tyrosine (PYY) in appetite controlKatie Wynne
Department of Metabolic Medicine, Imperial College London, and Hammersmith Hospital, UK
Nat Clin Pract Endocrinol Metab 2:612-20. 2006..This research suggests that modulation of these gut hormones could prove to be effective long-term therapies in the quest to combat the obesity epidemic...
- Appetite sensations and satiety quotient: predictors of energy intake and weight lossVicky Drapeau
Division of Kinesiology, Laval University and Laval Hospital Research Center, Ste Foy, Quebec, Canada G1K 7P4
Appetite 48:159-66. 2007..The aim of this study was to further evaluate the validity and clinical meaningfulness of appetite sensations to predict overall energy intake as well as body weight loss...
- Forebrain melanocortin signaling enhances the hindbrain satiety response to CCK-8James E Blevins
VA Puget Sound Health Care System, Mail stop S 151, 1660 South Columbian Way, Seattle, WA 98108, USA
Am J Physiol Regul Integr Comp Physiol 296:R476-84. 2009..melanocortin signaling in the hypothalamic paraventricular nucleus (PVN) participates in regulating this CCK satiety response, we administered the MC3/MC4R antagonist, SHU9119, into the PVN of rats before ip CCK-8 administration...
- Protein intake and energy balanceMargriet S Westerterp-Plantenga
Department of Human Biology, NUTRIM, and Wageningen Centre of Food Sciences, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
Regul Pept 149:67-9. 2008..Therefore 'high protein negative energy balance diets' aim to keep the grams of proteins ingested at the same level as consumed at energy balance, despite lower energy intakes...
- Appetite sensations as a marker of overall intakeVicky Drapeau
Division of Kinesiology, Laval University, Ste Foy, Quebec, Canada, G1K 7P4
Br J Nutr 93:273-80. 2005..Thus, assessment of appetite sensation such as fullness in response to a fixed load may be useful to evaluate individual overall energy intake...
- Effect of a protein preload on food intake and satiety feelings in response to duodenal fat perfusions in healthy male subjectsSibylle Oesch
Division of Gastroenterology, University Hospital, CH 4031 Basel, Switzerland
Am J Physiol Regul Integr Comp Physiol 289:R1042-7. 2005..Much more information is necessary to understand the basic physiological mechanisms that control food intake and satiety...
- Associations between postprandial insulin and blood glucose responses, appetite sensations and energy intake in normal weight and overweight individuals: a meta-analysis of test meal studiesAnne Flint
Novo Nordisk A S, Smørmosevej 2, Bagsvaerd, Denmark
Br J Nutr 98:17-25. 2007..We conclude that the postprandial insulin response may be an important satiety signal, and that central nervous system insulin resistance in overweight might explain the blunted effect on appetite...
- Liquid and solid meal replacement products differentially affect postprandial appetite and food intake in older adultsApril J Stull
Pennington Biomedical Research Center, Baton Rouge, LA, USA
J Am Diet Assoc 108:1226-30. 2008....
- Postprandial response of plasma ghrelin levels to various test meals in relation to food intake, plasma insulin, and glucoseJohannes Erdmann
Department of Internal Medicine, Else Kröner Fresenius Center of Nutritional Medicine, Technical University of Munich, D 81675 Munich, Germany
J Clin Endocrinol Metab 89:3048-54. 2004....
- Effect of bite size and oral processing time of a semisolid food on satiationNicolien Zijlstra
Top Institute Food and Nutrition, Wageningen, Netherlands
Am J Clin Nutr 90:269-75. 2009..In previous studies we showed a clear effect of viscosity on ad libitum food intake and found indications that eating rate, bite size, and oral processing time (OPT) could play a role...
- Effect of viscosity on learned satiationM Mars
Top Institute Food and Nutrition, PO Box 557, NL 6700 AN, Wageningen, The Netherlands
Physiol Behav 98:60-6. 2009..04; p=0.31); after 10 exposures intake difference between the LED and HED yogurts was only 1.5+/-15 g. These results suggest that a higher viscosity facilitates learned satiation...
- Stimulus-outcome interactions during instrumental discrimination learning by rats and humansS de Wit
Department of Experimental PsychologyUniversity of Cambridge, Cambridge, England
J Exp Psychol Anim Behav Process 33:1-11. 2007..Moreover, responding was resistant to outcome devaluation following incongruent, but not congruent, training, suggesting that both humans and rats adopted a stimulus-response strategy to resolve the incongruent discrimination...
- In vivo imaging of intragastric gelation and its effect on satiety in humansCaroline L Hoad
Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK
J Nutr 134:2293-300. 2004..Agents that gel on contact with acid may be useful additions to weight-reducing diets. We hypothesize that this effect is due to distension in the gastric antrum and/or altered transport of nutrients to the small intestine in the lumps...
- Prolongation of intermeal interval by gastrin-releasing peptide depends upon time of deliveryP A Rushing
Department of Psychiatry, Cornell University Medical College, New York Hospital Cornell Medical Center, White Plains 10605, USA
Peptides 19:1439-42. 1998..These results are consistent with the hypothesis that endogenous GRP acts in conjunction with events occurring shortly after meal termination to extend the duration of the IMI...
- Filling yet fattening: stereotypical beliefs about the weight gain potential and satiation of foodsMichael E Oakes
Department of Psychology, University of Scranton, Scranton, PA 18510 4596, USA
Appetite 46:224-33. 2006..Apparently, food names have acquired reputation for promoting obesity and (to a lesser extent) hunger satisfaction that are not based on their nutrient profiles...
- Less activation of the left dorsolateral prefrontal cortex in response to a meal: a feature of obesityDuc Son N T Le
Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Phoenix, AZ 85016, USA
Am J Clin Nutr 84:725-31. 2006..The subjects received a meal proportional to their body size; therefore, the meal volume was different for each person...
- Tasting fat: cephalic phase hormonal responses and food intake in restrained and unrestrained eatersSusan R Crystal
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, United States
Physiol Behav 89:213-20. 2006..05). In conclusion, the sensory experience of tasting fat increases food intake in restrained eaters and increases vagal efferent activity compared to a non-fat food in both populations...
- Effect of gastric distension prior to eating on food intake and feelings of satiety in humansSibylle Oesch
Clinical Research Center, Department of Research, University Hospital, CH 4031 Basel, Switzerland
Physiol Behav 87:903-10. 2006..Cholecystokinin (CCK) and peptide YY (PYY) were not altered by gastric distension. Transient pure mechanical distension of the fundus or the antrum prior to a meal does not trigger satiation...
- Bolus tube feeding suppresses food intake and circulating ghrelin concentrations in healthy subjects in a short-term placebo-controlled trialRebecca J Stratton
Institute of Human Nutrition, School of Medicine, University of Southampton, Southampton, United Kingdom
Am J Clin Nutr 88:77-83. 2008..Previous investigations suggest continuous tube feeding (TF) schedules do not suppress appetite and food intake, but bolus TF has been little studied...
- Higher satiety ratings following yogurt consumption relative to fruit drink or dairy fruit drinkAmi Tsuchiya
Center for Public Health Nutrition and Nutritional Sciences Program, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
J Am Diet Assoc 106:550-7. 2006..To compare the satiating power of semisolid and liquid yogurts with fruit beverages and dairy fruit drinks...
- On the road to obesity: Television viewing increases intake of high-density foodsElliott M Blass
Department of Psychology and Program in Neuroscience and Behavior, University of Massachusetts, Amherst, MA 01003, USA
Physiol Behav 88:597-604. 2006..Thus, watching television increases the amount eaten of high-density, palatable, familiar foods and may constitute one vector contributing to the current obesity crisis...
- Energy density and macronutrient composition determine flavor preference conditioned by intragastric infusions of mixed dietsKaren Ackroff
Department of Psychology, Brooklyn College and The Graduate Center, City University of New York, Brooklyn, NY 11210, USA
Physiol Behav 89:250-60. 2006..The differential satiating effects of fat and carbohydrate may contribute to these density-dependent preferences...
- The effect of increased beverage portion size on energy intake at a mealJulie E Flood
Department of Nutritional Sciences, The Pennsylvania State University, 226 Henderson Building, University Park, PA 16802 6501, USA
J Am Diet Assoc 106:1984-90; discussion 1990-1. 2006..This study examined the impact of increasing beverage portion size on beverage and food intake...
- Meal-related changes in ghrelin, peptide YY, and appetite in normal weight and overweight childrenJefferson P Lomenick
Department of Pediatrics, Division of Endocrinology, University of Kentucky, Lexington, KY, USA
Obesity (Silver Spring) 16:547-52. 2008..Our objectives were to characterize the patterns of secretion of these hormones in response to feeding in school-age children and determine whether there were differences between normal weight (NW) and overweight (OW) subjects...
- Whey proteins in the regulation of food intake and satietyBohdan L Luhovyy
Department of Nutritional Sciences, University of Toronto, Rm 329, Fitzgerald Building, 150 College St, Toronto, Ontario, Canada
J Am Coll Nutr 26:704S-12S. 2007..The effects described have been observed in short-term experiments and when whey is consumed in much higher amounts...
- Neuroendocrine control of food intakeElena Valassi
Chair of Endocrinology, University of Milan, Ospedale San Luca IRCCS, Istituto Auxologico Italiano, Via Spagnoletto 3, 20149 Milan, Italy
Nutr Metab Cardiovasc Dis 18:158-68. 2008..In conclusion, the present work reviews the most recent insights into the complex and redundant molecular mechanisms regulating food intake, focusing on the most encouraging perspectives for the treatment of obesity...
- Acute effects on metabolism and appetite profile of one meal difference in the lower range of meal frequencyAstrid J Smeets
Department of Human Biology, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
Br J Nutr 99:1316-21. 2008..In healthy, normal-weight women, decreasing the inter-meal interval sustains satiety, particularly during the day, and sustains fat oxidation, particularly during the night...
- The role of peptide YY in integrative gut physiology and potential role in obesityApril B M Grudell
Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Curr Opin Endocrinol Diabetes Obes 14:52-7. 2007..Peptide YY (PYY) - one of the major anorexigenic (satiation-causing) gastrointestinal peptides - when administered peripherally, leads to decreased food intake and hunger scores...
- [The regulation of body mass and its relation to the development of obesity]Attila Juhasz
Sopron MJV Erzsébet Kórház, a DE OEC Oktató Kórháza Belgyógyászat Sopron Gyori
Orv Hetil 148:1827-36. 2007....
- Less activation in the left dorsolateral prefrontal cortex in the reanalysis of the response to a meal in obese than in lean women and its association with successful weight lossDuc Son Nt Le
Obesity and Diabetes Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Phoenix, AZ 85016, USA
Am J Clin Nutr 86:573-9. 2007....
- Test meal intake in obese binge eaters in relation to impulsivity and compulsivityKochavi Galanti
Ferkauf Graduate School of Psychology and Albert Einstein College of Medicine, Yeshiva University, Bronx, New York, USA
Int J Eat Disord 40:727-32. 2007..Studies have linked increased impulsivity and compulsivity with bulimia nervosa (BN). Less is known about this relationship in binge eating disorder (BED)...
- Soup preloads in a variety of forms reduce meal energy intakeJulie E Flood
The Pennsylvania State University, 226 Henderson Building, University Park, PA 16802, USA
Appetite 49:626-34. 2007..The type of soup had no significant effect on test meal intake or total meal energy intake. Consuming a preload of low-energy-dense soup, in a variety of forms, is one strategy for moderating energy intake in adults...
- Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese malesBirgitte Sloth
Dept of Human Nutrition, Centre for Advanced Food Studies, Faculty of Life Sciences, Univ of Copenhagen, 30 Rolighedsvej, DK 1958 Frederiksberg, Denmark
Am J Physiol Endocrinol Metab 293:E604-9. 2007..PYY(1-36) is unlikely to be important in regulating energy intake. The PYY(3-36) administrations caused a non-dose-dependent mobilization of FFA, likely through a direct effect...
- Effects of solid versus liquid meal-replacement products of similar energy content on hunger, satiety, and appetite-regulating hormones in older adultsS M Tieken
Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA
Horm Metab Res 39:389-94. 2007..To examine whether solid versus liquid meal-replacement products differentially affect appetite and appetite-regulating hormones in older adults...
- Altering portion sizes and eating rate to attenuate gorging during a fast food meal: effects on energy intakeCara B Ebbeling
Division of Endocrinology, Department of Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Pediatrics 119:869-75. 2007..Eating large amounts of food at a rapid rate, defined as gorging, may contribute to excess energy intake. We aimed to evaluate whether altering portion sizes and eating rate could decrease energy intake during an extra-large fast food meal...
- Understanding the mechanisms of food intake and obesityE T Rolls
Department of Experimental Psychology, University of Oxford, Oxford, UK
Obes Rev 8:67-72. 2007
- Effects of a combination fiber system on appetite and energy intake in overweight humansRichard D Mattes
Department of Foods and Nutrition, Purdue University, 700 W State Street, W Lafayette, IN 47907 2059, United States
Physiol Behav 90:705-11. 2007....
- [Pharmacotherapy of obesity]Volker Schusdziarra
Else Kröner Fresenius Zentrum für Ernährungsmedizin Kilinikum rechts der Isar, TU Munchen
Pharm Unserer Zeit 35:500-4. 2006
- Psychobiological effects observed in obese men experiencing body weight loss plateauJean Philippe Chaput
Division of Kinesiology, Department of Social and Preventive Medicine, Faculty of Medicine, Laval University, Sainte Foy, Quebec, Canada
Depress Anxiety 24:518-21. 2007....
- Gastrointestinal regulation of food intake: general aspects and focus on anandamide and oleoylethanolamideR Capasso
Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
J Neuroendocrinol 20:39-46. 2008..Additionally, these acylethanolamides, whose gastric levels change in response to diet-induced obesity, alter gastrointestinal motility, which might contribute to their effect on food intake and nutrient absorption...
- Volume and variety: relative effects on food intakeG N M Norton
School of Psychology, University of Liverpool, Liverpool L69 7ZA, UK
Physiol Behav 87:714-22. 2006..Clearly volume effects on intake rely both on amount consumed and energy density. As predicted, variety stimulated food intake and this occurred across volume conditions...
- The appetite-suppressant effect of nicotine is enhanced by caffeineA Jessen
Research Department of Human Nutrition, Centre for Advanced Food Studies, The Royal Veterinary and Agricultural University, Denmark
Diabetes Obes Metab 7:327-33. 2005..To test whether the anorectic effect of nicotine may be amplified by caffeine...
- Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapyDonald A Williamson
Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
Appetite 45:75-80. 2005..These results are discussed in the context of the scientific literature pertaining to leptin and its effects on appetite and obesity...
- Total subdiaphragmatic vagotomy does not suppress high protein diet-induced food intake depression in ratsDiane L'Heureux-Bouron
Unité INRA 914 de Physiologie de la Nutrition et du Comportement Alimentaire, Institut National Agronomique Paris Grignon, F75231 Paris Cedex 05, France
J Nutr 133:2639-42. 2003..In contrast, a defect in this visceral regulating system could reinforce the metabolic-associated food intake depression signal...
- Dronabinol and marijuana in HIV(+) marijuana smokers: acute effects on caloric intake and moodMargaret Haney
New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
Psychopharmacology (Berl) 181:170-8. 2005..No studies to date have directly compared the tolerability and efficacy of smoked marijuana and oral dronabinol in HIV(+) marijuana smokers...
- Satiety signaling in Caenorhabditis elegansLeon Avery; Fiscal Year: 2013..ASI sensory neuron activity signals nutritional well-being and provokes a satiety response. 2...
- Role of Oxytocin Signaling in the Pathogenesis of Diet-Induced ObesityJAMES ERNEST BLEVINS; Fiscal Year: 2013..Defective activation of CCK-sensing neurons in the NTS and an impaired satiety response to CCK are predicted to result in enhanced susceptibility to DIO...
- Brain integration of adiposity and satiety signals in the control of food intakeDiana Williams; Fiscal Year: 2009..Next, we will investigate whether leptin reduces food intake and enhances the satiety response to gastrointestinal nutrients in part by modulating rats'sensitivity to endogenously released GLP-1 or ..
- Brain integration of adiposity and satiety signals in the control of food intakeDiana L Williams; Fiscal Year: 2011..Next, we will Investigate whether leptin reduces food Intake and enhances the satiety response to gastrointestinal nutrients in part by modulating rats'sensitivity to endogenously released GLP-1 or ..
- UPPER GI TRACT MEDIATION OF THE SATIETY EFFECT OF FATSDanielle Greenberg; Fiscal Year: 1992..stimuli; and (3) to examine the neural, endocrine or neuroendocrine mechanisms involved in mediating this satiety response in Sprague Dawley rats...
- Neural Mechanisms of Overeating in Prader-Willi SyndromeAnastasia Dimitropoulos; Fiscal Year: 2009..The specific focus of this project will be to identify if overeating in PWS is caused not only by abnormal satiety response but also by abnormally heightened responses to rewarding food during hunger and after attempted satiation...
- PYY3-36: a gut secreted peptide regulating satietyLLIA HALATCHEV; Fiscal Year: 2005..to PYY1-36 and also elucidate the physiological role of PYY3-36 as a peripheral feedback signal of the satiety response. Finally, we are interested in determining whether PYY3-36 is acting as a short or long-term peripheral ..
- FACTORS AFFECTING CALORIC REGULATION IN HUMAN FEEDINGBarbara Rolls; Fiscal Year: 2007..The experiments carefully vary fat content while keeping the energy content constant or vice versa, all while maintaining constant palatability. ..
- Food Rheology and Feeding in Lean and Obese HumansRichard Mattes; Fiscal Year: 2007..abstract_text> ..
- HEDONICS AND DIETARY INTAKE OF FATRichard Mattes; Fiscal Year: 2008..This will be explored through stable isotope tracer studies for Aim 3. The proposed work will hold important public health, clinical, commercial and basic biological implications. [unreadable] [unreadable]..
- CEPHALIC RESPONSES AND MEAL FEEDINGStephen Woods; Fiscal Year: 2008..unreadable] [unreadable]..
- OVARIAN HORMONAL CONTROL OF MEAL SIZENORCROSS GEARY; Fiscal Year: 2008..8) Determine the tonic and phasic effects of estradiol on glutamate synaptogenesis in the brainstem by using immunocytochemical detection of synaptic proteins. [unreadable] [unreadable]..
- Society for the Study of Ingestive Behavior Annual MeetTimothy Moran; Fiscal Year: 2003..abstract_text> ..
- Low Carbohydrate Diets: Feeding and Endocrine SignalingTimothy Moran; Fiscal Year: 2006..abstract_text> ..
- CONTROL OF ALCOHOL INTAKE BY BRAIN-GUT PEPTIDESNORCROSS GEARY; Fiscal Year: 2003..The work will be closely coordinated, and we expect this cooperative effort to be very productive. ..
- Metabolic and Epigenetic Effects of Maternal High Fat Diet in Obesity Prone RatsTimothy H Moran; Fiscal Year: 2010..The results of these experiments will enhance our understanding of the etiology of obesity and metabolic disease ultimately allowing the development of rational clinical interventions for such conditions. ..
- ALCOHOL APPETITE--A NUTRIENT CONDITIONING ANALYSISKaren Ackroff; Fiscal Year: 2001..It will advance our basic knowledge of the psychobiology of alcohol appetite and may provide practical benefits for controlling alcohol consumption in humans. ..
- DIETARY OBESITYGeorge Bray; Fiscal Year: 2007..We now propose these well founded, important and exciting studies which will provide critical new insights into anatomical, physiological and molecular mechanisms by which high levels of dietary fat induce obesity. ..
- Programmed adiposity: genetic in utero and postnatal determinantsEric Zorrilla; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- NEURAL AND GI SUBSTRATES IN BOMBESIN SATIETYELLEN LADENHEIM; Fiscal Year: 2006..Such an understanding will significantly enhance our understanding of the mechanisms underlying overall energy regulation and may lead to novel treatments for obesity or eating disorders ..
- Neuropharmacology of Learned Food PreferencesAnthony Sclafani; Fiscal Year: 2009..It will advance our understanding of the basic mechanisms involved in the development of food preferences and may provide insights into the clinical treatment of overeating and obesity. ..
- Urocortins Brain CRF2 Receptors and Energy BalanceEric P Zorrilla; Fiscal Year: 2010....
- CHANGES IN REINFORCER VALUE AND REINFORCER RELATIVITYFRANCES MCSWEENEY; Fiscal Year: 2002..Because operant principles are often used to understand and to treat health-related problems (e.g., drug taking, obesity), this research may have many implications for both theory and practice in the area of health. ..
- Galanin Control of Food Intake: Molecular, Neuroanatomical and Behavioral BasesEric P Zorrilla; Fiscal Year: 2010....
- Role of the CRF2 Receptor in Ingestive BehaviorEric Zorrilla; Fiscal Year: 2005..The proposed studies will address these questions as well to understand better the role of the CRF2 receptor in feeding behavior. ..
- 5-HT3 receptor mediation of 5-HT & CCK-induced satiationMatthew Hayes; Fiscal Year: 2005....
- Childhood obesity treatment targeting specific behaviorsHollie Raynor; Fiscal Year: 2007..Moreover, by comparing the effects of targeting the traditional or substitute behaviors, data will be obtained for a power analysis for a full-scale trial of the effects of these two approaches on long-term weight loss. ..
- Dorsomedial Hypothalamic Signaling Pathways and Energy BalanceSheng Bi; Fiscal Year: 2010..Overall, the elucidation of the actions of these DMH peptide systems in feeding and body weight control would significantly advance our understanding of the role of this hypothalamic nucleus in maintaining energy homeostasis. ..
- SH2-B regulation of body weight and energy homeostasisLiangyou Rui; Fiscal Year: 2010..3. Determine whether SH2-B differentially regulates leptin sensitivity in the LEPRb-neurons governing energy intake versus energy expenditure. ..
- Characterization of a novel brain cannabinoid ligandDaniele Piomelli; Fiscal Year: 2010..The objective of our research is to understand how these transmitters are produced and eliminated, and discover innovative medicines that target these processes. ..
- EFFECTS OF CHANGING SEDENTARY BEHAVIOR IN OBESE CHILDRENLeonard Epstein; Fiscal Year: 2008..Developing a better understanding of why obese youth increase physical activity or decrease energy intake when sedentary behaviors are reduced is important for the treatment of pediatric obesity. [unreadable] [unreadable] [unreadable]..
- Young Adult Environmental and Physical Activity DynamicsBarry Popkin; Fiscal Year: 2008..No study heretofore has had large-scale groupings and in-depth environmental measures over time to examine these issues in a dynamic manner. ..
- Role of Endocannabinoids in the Behavioral Consequences of Social IsolationDaniele Piomelli; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Peer Influence on Eating Behavior in Overweight and Normal Weight YouthsSarah Jeanne Salvy; Fiscal Year: 2008..This study is designed to understand differences in responses to the social and food environment between overweight and non overweight youths. [unreadable] [unreadable] [unreadable]..
- BEHAVIORAL TOXICITY OF MDMA IN RHESUS MONKEYSMICHAEL TAFFE; Fiscal Year: 2009..Specific Aim IV: To determine if a history of MDMA exposure impairs acquisition and performance of a battery of neuropsychological tests. ..
- Addressing Fear of Food in Anorexia NervosaJoanna Steinglass; Fiscal Year: 2009..This grant proposes a new and innovative treatment for patients with anorexia nervosa, which if successful, will reduce this high relapse rate and could have implications for acute treatment of anorexia nervosa, as well. ..
- Functional Brain Imaging and Appetite-Related Hormones Pre and Post Obesity SurgeAllan Geliebter; Fiscal Year: 2008..This may lead to improvements in the surgical procedures and to new insights into basic mechanisms that lead to obesity, which could provide the basis for new less invasive treatments. ..
- Diet, Activity, Obesity & The Built Environment DynamicsBarry Popkin; Fiscal Year: 2009..A central issue is determining modifiable environment factors that may reduce ethnic and socioeconomic differentials in health status. ..
- Nutritional and Hormonal Determinants of Peak Bone MassMadhusmita Misra; Fiscal Year: 2008..The effects of estrogen in weight recovered vs. non-weight recovered AN will also be studied. ..
- Genes mediating glucopenia-induced obesity in nematodesCharles Mobbs; Fiscal Year: 2008..These studies will suggest potential targets for anti-obesity drugs. ..
- Wise Mind: Environmental Approach for Obesity PreventionDonald Williamson; Fiscal Year: 2004..abstract_text> ..
- Leptin and Neuroendocrine Gene Regulation in ObesityJudith Korner; Fiscal Year: 2005..Leibel and Dr. Wardlaw, are experienced in basic and clinical research. They are easily accessible, enthusiastic about my projects, and will facilitate my transition to status as an independent investigator. ..
- PREVENTION OF OBESITY BY ALTERATION OF DIETARY FATJoseph Donnelly; Fiscal Year: 2005..The results of this study should advance our understanding of the role of dietary fat in the prevention of obesity and weight re-gain. ..
- AUTONOMIC DIABETIC NEUROPATHY IN MICECharles Mobbs; Fiscal Year: 2004..The present study should clarify the mechanisms and significance of glucose-sensitive hypothalamic and brainstem neurons in autonomic diabetic neuropathy. ..
- SIV Behavioral Pathology: Manipulation of Viral LoadMICHAEL TAFFE; Fiscal Year: 2004..abstract_text> ..
- Role of CNS Insulin in Learning and MemoryStephen Benoit; Fiscal Year: 2003..Ultimately, this line of investigation may offer novel therapeutic strategies for treating individuals with cognitive disorders such as Alzheimer' s disease. ..
- GONADAL STEROID REGULATION OF THE BIOLOGICAL CLOCKTamas Horvath; Fiscal Year: 2003..abstract_text> ..
- PURDUE INTEGRATIVE NEUROSCIENCE PROGRAMTERRY POWLEY; Fiscal Year: 2002..Students trained in the interdisciplinary Purdue Integrative Neuroscience program will make substantial contributions to mental health research and its applications in the next century. ..
- BCHE as a Cocaine AntagonistJames Woods; Fiscal Year: 2002..The possibility that human BChE can eventually be used as a safe and effective treatment of cocaine abuse and toxicity is being explored through these studies. ..
- Oleylethanolamide derivatives as anti-obesity agentsDaniele Piomelli; Fiscal Year: 2005....
- CRH Antagonists for Treatment of Drug AbuseJames Woods; Fiscal Year: 2005..This may provide information about the etiology of drug abuse, as well as data on the potential treatment of drug abuse in normal, or particularly, in stressed individuals. ..
- Uncoupling Protein 2 Promotes Neuronal SurvivalTamas Horvath; Fiscal Year: 2006..This will furnish one common target for the development of drugs against a variety of neurodegenerative pathologies, including those associated with hypoxia, epilepsy, Parkinson's, Alzheimer's and Huntington's Disease. ..
- Chromium Effects in Imparied Glucose ToleranceDavid Katz; Fiscal Year: 2006..By contributing to knowledge related to potential diabetes prevention strategies, this study addresses one of the more pressing public health issues in the US today. ..
- Uncoupling Proteins and Species-Dependent LongevityTamas Horvath; Fiscal Year: 2007..Our attempts to provide comparative analyses of age related molecular mechanisms in rodents and nonhuman primates, will provide novel therapeutic targets, UCPs, to increase longevity without compromising tissue function. ..
- CENTRAL PEPTIDERGIC CIRCUITS IN METABOLISM REGULATIONTamas Horvath; Fiscal Year: 2007..abstract_text> ..
- IV COCAINE ABUSE TREATMENT: A LABORATORY MODELRICHARD FOLTIN; Fiscal Year: 2007..abstract_text> ..
- Amygdala circuits and control of feeding by learned cuesGORICA PETROVICH; Fiscal Year: 2007..All facilities required for the proposed research are available to the applicant, including dedicated office and research space. ..
- LABORATORY ANALYSIS OF COCAINE ABSTINENCERICHARD FOLTIN; Fiscal Year: 2007..abstract_text> ..
- Syndecan & CNS Melanocortin Signaling in Energy BalanceStephen Benoit; Fiscal Year: 2007..The results may provide important, basic insights into the control of body weight by the central melanocortin system and its recently identified co-receptor, syndecan-3. ..
- NARCOTIC DRUG AND OPIOID PEPTIDE BASIC RESEARCH PROJECTJames Woods; Fiscal Year: 2006..abstract_text> ..
- Melanin-Concentrating Hormone and Alcohol IntakeElizabeth Duncan; Fiscal Year: 2005..The specific aims are: 1) To test the hypothesis that MCH is an endogenous factor regulating alcohol consumption and, 2) To test the hypothesis that MCH regulates the motivation to consume alcohol by modulating its reward properties. ..
- STOMACH CAPACITY AND EMPTYING IN OBESITYAllan Geliebter; Fiscal Year: 2001..Body weight and composition will be assessed at the start and monthly. The studies may enhance knowledge of the etiology, pathophysiology, and treatment of BED. ..