satiation

Summary

Summary: Full gratification of a need or desire followed by a state of relative insensitivity to that particular need or desire.

Top Publications

  1. ncbi Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies
    A Flint
    Research Department of Human Nutrition, Center for Food Research, The Royal Veterinary and Agricultural University, DK 1958 Frederiksberg C, Denmark
    Int J Obes Relat Metab Disord 24:38-48. 2000
  2. ncbi Eat and run? The hunger/satiation hypothesis in vertical migration: history, evidence and consequences
    Sifford Pearre
    Department of Oceanography, Dalhousie University, Halifax, Nova Scotia, Canada B3H 3M2
    Biol Rev Camb Philos Soc 78:1-79. 2003
  3. pmc Appetite control: methodological aspects of the evaluation of foods
    J Blundell
    Institute of Psychological Sciences, University of Leeds, Leeds
    Obes Rev 11:251-70. 2010
  4. ncbi Portion size of food affects energy intake in normal-weight and overweight men and women
    Barbara J Rolls
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802 6501, USA
    Am J Clin Nutr 76:1207-13. 2002
  5. pmc Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol
    Tim C Kirkham
    Department of Psychology, University of Reading, Earley Gate, Whiteknights, Reading RG6 6AL, UK
    Br J Pharmacol 136:550-7. 2002
  6. ncbi Fasting increases and satiation decreases olfactory detection for a neutral odor in rats
    P Aimé
    Laboratoire de Neurosciences Sensorielles, Comportement, Cognition, CNRS, UMR 5020, Universite Claude Bernard Lyon 1, 50 avenue Tony Garnier, 69366 Lyon Cedex 07, France
    Behav Brain Res 179:258-64. 2007
  7. pmc Beverage consumption, appetite, and energy intake: what did you expect?
    Bridget A Cassady
    Department of Nutrition Science, Purdue University, West Lafayette, IN 47907 2059, USA
    Am J Clin Nutr 95:587-93. 2012
  8. pmc The relationship between dietary energy density and energy intake
    Barbara J Rolls
    The Department of Nutritional Sciences, 226 Henderson Building, The Pennsylvania State University, University Park, PA 16802 6501, USA
    Physiol Behav 97:609-15. 2009
  9. ncbi Gastrointestinal mechanisms of satiation for food
    Robert C Ritter
    Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, and Programs in Neuroscience, College of Veterinary Medicine, Washington State University, Pullman, WA 99164 6520, USA
    Physiol Behav 81:249-73. 2004
  10. ncbi Effect of bite size and oral processing time of a semisolid food on satiation
    Nicolien Zijlstra
    Top Institute Food and Nutrition, Wageningen, Netherlands
    Am J Clin Nutr 90:269-75. 2009

Detail Information

Publications273 found, 100 shown here

  1. ncbi Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies
    A Flint
    Research Department of Human Nutrition, Center for Food Research, The Royal Veterinary and Agricultural University, DK 1958 Frederiksberg C, Denmark
    Int J Obes Relat Metab Disord 24:38-48. 2000
    ..To examine reproducibility and validity of visual analogue scales (VAS) for measurement of appetite sensations, with and without a diet standardization prior to the test days...
  2. ncbi Eat and run? The hunger/satiation hypothesis in vertical migration: history, evidence and consequences
    Sifford Pearre
    Department of Oceanography, Dalhousie University, Halifax, Nova Scotia, Canada B3H 3M2
    Biol Rev Camb Philos Soc 78:1-79. 2003
    ..gut contents, and reviews the evidence for the hypothesis that such movements are in fact driven by hunger and satiation. The more recently appreciated vertical migrations of phytoplankters and their similarities in form and driving ..
  3. pmc Appetite control: methodological aspects of the evaluation of foods
    J Blundell
    Institute of Psychological Sciences, University of Leeds, Leeds
    Obes Rev 11:251-70. 2010
    ..The report includes different designs for assessing effects on satiation as opposed to satiety, detailed coverage of the extent to which a change in hunger can stand alone as a measure ..
  4. ncbi Portion size of food affects energy intake in normal-weight and overweight men and women
    Barbara J Rolls
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802 6501, USA
    Am J Clin Nutr 76:1207-13. 2002
    ..Large portions of food may contribute to excess energy intake and greater obesity. However, data on the effects of portion size on food intake in adults are limited...
  5. pmc Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol
    Tim C Kirkham
    Department of Psychology, University of Reading, Earley Gate, Whiteknights, Reading RG6 6AL, UK
    Br J Pharmacol 136:550-7. 2002
    ..2-AG) levels in feeding-associated brain regions of rats, during fasting, feeding of a palatable food, or after satiation. Endocannabinoid levels were compared to those in rats fed ad libitum, at a point in their daily cycle when ..
  6. ncbi Fasting increases and satiation decreases olfactory detection for a neutral odor in rats
    P Aimé
    Laboratoire de Neurosciences Sensorielles, Comportement, Cognition, CNRS, UMR 5020, Universite Claude Bernard Lyon 1, 50 avenue Tony Garnier, 69366 Lyon Cedex 07, France
    Behav Brain Res 179:258-64. 2007
    ..This would have an obvious eco-ethological role by increasing the relevance of olfactory inputs when seeking food...
  7. pmc Beverage consumption, appetite, and energy intake: what did you expect?
    Bridget A Cassady
    Department of Nutrition Science, Purdue University, West Lafayette, IN 47907 2059, USA
    Am J Clin Nutr 95:587-93. 2012
    ..Beverage consumption is implicated in the overweight/obesity epidemic through the weaker energy compensation response it elicits compared with solid food forms. However, plausible mechanisms are not documented...
  8. pmc The relationship between dietary energy density and energy intake
    Barbara J Rolls
    The Department of Nutritional Sciences, 226 Henderson Building, The Pennsylvania State University, University Park, PA 16802 6501, USA
    Physiol Behav 97:609-15. 2009
    ..Ad libitum intake or satiation has also been shown to be influenced by ED when the proportions of macronutrients are constant...
  9. ncbi Gastrointestinal mechanisms of satiation for food
    Robert C Ritter
    Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, and Programs in Neuroscience, College of Veterinary Medicine, Washington State University, Pullman, WA 99164 6520, USA
    Physiol Behav 81:249-73. 2004
    b>Satiation for food comprises the physiological processes that result in the termination of eating...
  10. ncbi Effect of bite size and oral processing time of a semisolid food on satiation
    Nicolien Zijlstra
    Top Institute Food and Nutrition, Wageningen, Netherlands
    Am J Clin Nutr 90:269-75. 2009
    ..In previous studies we showed a clear effect of viscosity on ad libitum food intake and found indications that eating rate, bite size, and oral processing time (OPT) could play a role...
  11. ncbi Habitual physical activity differentially affects acute and short-term energy intake regulation in young and older adults
    E L Van Walleghen
    Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA 24061, USA
    Int J Obes (Lond) 31:1277-85. 2007
    ..Energy intake (EI) regulation is impaired in older adults, but it is not known if habitual physical activity affects accuracy of EI regulation in older compared with young adults...
  12. ncbi Both longer oral sensory exposure to and higher intensity of saltiness decrease ad libitum food intake in healthy normal-weight men
    Dieuwerke P Bolhuis
    Product Design and Quality Management Group, Wageningen University, Wageningen, The Netherlands
    J Nutr 141:2242-8. 2011
    Orosensory exposure to sweetness has been shown to be important in satiation, whereas the effect of exposure to a salty taste on satiation is not known...
  13. ncbi Development and testing of a labeled magnitude scale of perceived satiety
    Armand V Cardello
    Science and Technology Directorate, US Army Natick Soldier Center, Natick, MA 01760 5020, USA
    Appetite 44:1-13. 2005
    ..It is concluded that the SLIM scale is a sensitive, reliable, and easy-to-use scale for measuring perceived satiety that has several advantages over other, more commonly used satiety scales...
  14. ncbi Effect of proteins from different sources on body composition
    J A Gilbert
    Division of Kinesiology, Faculty of Medicine, Laval University, Canada
    Nutr Metab Cardiovasc Dis 21:B16-31. 2011
    ..Protein intake enhances energy expenditure, satiety and fat loss, but there is no clear evidence to indicate whether there is a difference in the effect dependent on the source of the protein, i.e. from animal or plant-based foods...
  15. ncbi Oral processing characteristics of solid savoury meal components, and relationship with food composition, sensory attributes and expected satiation
    C G Forde
    Nestle Research Centre, Vers chez les Blanc, Switzerland
    Appetite 60:208-19. 2013
    ..To better design meals that promote greater feelings of satiation, we need an accurate picture of the oral processing characteristics of a range of solid food items that could be ..
  16. pmc The addition of a protein-rich breakfast and its effects on acute appetite control and food intake in 'breakfast-skipping' adolescents
    H J Leidy
    Department of Dietetics and Nutrition, University of Kansas Medical Center KUMC, Kansas City, KS 66160, USA
    Int J Obes (Lond) 34:1125-33. 2010
    ..It is unclear whether the addition of breakfast, with emphasis on dietary protein, leads to better appetite and energy intake regulation in adolescents...
  17. ncbi Texture, not flavor, determines expected satiation of dairy products
    Pleunie S Hogenkamp
    Top Institute Food and Nutrition, PO Box 557, NL 6700 AN, Wageningen, The Netherlands
    Appetite 57:635-41. 2011
    ..Our objective is to investigate the role of sensory attributes and means of consumption in the expected satiation of dairy products...
  18. ncbi Pre-meal water consumption reduces meal energy intake in older but not younger subjects
    Emily L Van Walleghen
    Department of Human Nutrition, Foods and Exercise, 221 Wallace Hall 0430, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    Obesity (Silver Spring) 15:93-9. 2007
    ..To determine whether the consumption of water 30 minutes before an ad libitum meal reduces meal energy intake in young and older adults...
  19. ncbi 'Expected satiety' changes hunger and fullness in the inter-meal interval
    Jeffrey M Brunstrom
    Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, United Kingdom
    Appetite 56:310-5. 2011
    ..Potential explanations are discussed, including the prospect that satiety is moderated by memories of expected satiety that are encoded around the time that a meal is consumed...
  20. pmc Regional brain response to visual food cues is a marker of satiety that predicts food choice
    Sonya Mehta
    Departments of Radiology and the Diabetes and Obesity Center of Excellence, University of Washington, Seattle, WA, USA
    Am J Clin Nutr 96:989-99. 2012
    ..Neuronal processes that underlie the subjective experience of satiety after a meal are not well defined...
  21. ncbi Sip size of orangeade: effects on intake and sensory-specific satiation
    Pascalle L G Weijzen
    Wageningen University, The Netherlands
    Br J Nutr 102:1091-7. 2009
    Sensory-specific satiation (SSS) drives food selection and contributes to meal termination. We hypothesised that smaller sips would increase SSS due to increased oro-sensory exposure, irrespective of energy content...
  22. ncbi Effect of satiety on brain activation during chocolate tasting in men and women
    Paul A M Smeets
    Image Sciences Institute and the Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands
    Am J Clin Nutr 83:1297-305. 2006
    ..A key factor controlling food intake is selective satiety, ie, the phenomenon that the motivation to eat more of a food decreases more than does the motivation to eat foods not eaten...
  23. ncbi Activation of the human orbitofrontal cortex to a liquid food stimulus is correlated with its subjective pleasantness
    M L Kringelbach
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
    Cereb Cortex 13:1064-71. 2003
    ....
  24. pmc Measuring and modeling the interaction among reward size, delay to reward, and satiation level on motivation in monkeys
    Takafumi Minamimoto
    Laboratory of Neuropsychology, National Institute of Mental Health, National Institute Health, Department of Health and Human Services, Bethesda, MD 20892 4415, USA
    J Neurophysiol 101:437-47. 2009
    ..We also inferred the state of one internal factor, level of satiation, by monitoring the accumulated reward...
  25. ncbi Changes in gut hormone and glucose concentrations in relation to hunger and fullness
    Sofie G Lemmens
    Top Institute Food and Nutrition, Wageningen, Netherlands
    Am J Clin Nutr 94:717-25. 2011
    ..The search for biomarkers of appetite is very active...
  26. ncbi C-fos protein expression in the nucleus of the solitary tract correlates with cholecystokinin dose injected and food intake in rats
    T T Zittel
    University Hospital, Department of General and Transplantation Surgery, Hoppe Seyler Str 3, University of Tubingen, Tubingen, Germany
    Brain Res 846:1-11. 1999
    ..Our data indicate that subpopulations of the NTS that are activated by CCK or food intake are involved into the short-term regulation of food intake and the neural control of feeding by the caudal brainstem...
  27. pmc Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    A Flint
    Research Department of Human Nutrition, Center for Food Research, The Royal Veterinary and Agricultural University, DK 1958 Frederiksberg C, Denmark
    J Clin Invest 101:515-20. 1998
    ..002). In conclusion, the results show that GLP-1 enhanced satiety and reduced energy intake and thus may play a physiological regulatory role in controlling appetite and energy intake in humans...
  28. ncbi Intense sweeteners, energy intake and the control of body weight
    F Bellisle
    France Bellisle, INRA, CRNH Ile de France, Paris XIII Leonard de Vinci, Bobigny, France
    Eur J Clin Nutr 61:691-700. 2007
    ....
  29. pmc Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia
    J Tack
    Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    Gut 52:1271-7. 2003
    ..Impaired gastric accommodation is a major pathophysiological mechanism in functional dyspepsia. The aim of the present work was to assess a satiety drinking test in the evaluation of accommodation in health and dyspepsia...
  30. ncbi Changes in rat olfactory detection performance induced by orexin and leptin mimicking fasting and satiation
    A K Julliard
    Laboratoire de Neurosciences Sensorielles, Comportement, Cognition, CNRS, UMR 5020, Universite de Lyon, Lyon 1, 50 avenue Tony Garnier, 69366 Lyon Cedex 07, France
    Behav Brain Res 183:123-9. 2007
    ..Orexin and leptin modulate the olfactory performance in a similar way as do physiological induced fasting and satiation and appear to be important factors in the interdependency of olfaction and food intake.
  31. ncbi Playing a computer game during lunch affects fullness, memory for lunch, and later snack intake
    Rose E Oldham-Cooper
    Department of Experimental Psychology, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 93:308-13. 2011
    ..The presence of distracting stimuli during eating increases the meal size and could thereby contribute to overeating and obesity. However, the effects of within-meal distraction on later food intake are less clear...
  32. pmc Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    Matthew R Hayes
    Graduate Groups of Psychology and Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Endocrinology 150:2654-9. 2009
    ..central GLP-1R activity is involved in the control of normal feeding and examined which gastrointestinal satiation signals contribute to this control...
  33. pmc Impaired satiation and increased feeding behaviour in the triple-transgenic Alzheimer's disease mouse model
    Adedolapo Adebakin
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 7:e45179. 2012
    ..These data demonstrate that 3×TgAD mice show increased feeding behaviour and insensitivity to satiation, which is possibly due to defective gut-brain signalling in response to endogenous satiety factors released by ..
  34. pmc Brain responses to high-protein diets
    Marion Journel
    AgroParisTech, UMR914 Nutrition Physiology and Ingestive Behavior, Paris, France
    Adv Nutr 3:322-9. 2012
    ....
  35. ncbi Perceived volume, expected satiation, and the energy content of self-selected meals
    Jeffrey M Brunstrom
    University of Bristol, England, UK
    Appetite 55:25-9. 2010
    ..Previously, we have shown that expected satiation is an excellent predictor of the energy content of self-selected meals...
  36. ncbi Gastric satiation is volumetric, intestinal satiation is nutritive
    Terry L Powley
    Department of Psychological Sciences, Purdue University, 703 Third Street, West Lafayette, IN 47907 2081, USA
    Physiol Behav 82:69-74. 2004
    Gerry Smith's thoughtful survey in his book Satiation (1998) outlined the established principles of gastric and intestinal satiation and delineated several questions still requiring clarification...
  37. ncbi Isocaloric meal and snack foods differentially affect eating behavior
    Elizabeth D Capaldi
    University at Buffalo, SUNY, 206 Park Hall, Buffalo, NY 14260, USA
    Appetite 46:117-23. 2006
    ..e. whether they are part of a meal or snack). These results are discussed in terms of how cognitive representations of preload foods can influence subsequent consumption...
  38. ncbi Effects on hunger and satiety, perceived portion size and pleasantness of taste of varying the portion size of foods: a brief review of selected studies
    Tanja V E Kral
    Weight and Eating Disorders Program, University of Pennsylvania School of Medicine, 3535 Market Street, 3rd Floor, Philadelphia, PA 19104, USA
    Appetite 46:103-5. 2006
    ..g. learning, social norms, monetary considerations), and post-ingestive consequences (e.g. sensations of hunger and fullness) related to the portion size of foods may interact to affect the amount of food that is consumed during a meal...
  39. ncbi beta-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term
    Paola Vitaglione
    Department of Food Science, University of Naples, Via Universita 100, 80055 Portici Na, Italy
    Appetite 53:338-44. 2009
    ..Barley beta-glucans were able to control appetite in the short term by modulating sensations and reducing energy intake. Data suggested for the first time that satiety effect of beta-glucans are mediated by ghrelin and PYY...
  40. ncbi Impact of some isoenergetic snacks on satiety and next meal intake in healthy adults
    E Almiron-Roig
    Nestle Research Centre, Vers chez les Blanc, Lausanne, Switzerland
    J Hum Nutr Diet 22:469-74. 2009
    ..The present study compared the satiating properties of small servings of four low energy foods [465 kJ (111 kcal)] including a drinking yogurt enhanced for satiety...
  41. ncbi Added soluble fiber enhances the satiating power of low-energy-density liquid yogurts
    Martine M Perrigue
    Nutritional Sciences Program, School of Public Health, University of Washington, Seattle, WA 98195, USA
    J Am Diet Assoc 109:1862-8. 2009
    ..Low-energy-density foods with high satiating power may be useful tools for weight management. Energy density of yogurts can range from 0.4 to 1.8 kcal/g...
  42. ncbi Understanding variety: tasting different foods delays satiation
    Marion M Hetherington
    School of Psychology, University of Liverpool, Liverpool, L69 7ZA, UK
    Physiol Behav 87:263-71. 2006
    ..Varying sensory and other characteristics of foods could sustain interest in eating and delay the development of satiation. Two experiments set out to explore this by investigating the effect of introducing different foods to taste and ..
  43. ncbi Consumption of caloric and non-caloric versions of a soft drink differentially affects brain activation during tasting
    Paul A M Smeets
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuroimage 54:1367-74. 2011
    ..In addition, implications for the effectiveness of non-caloric sweeteners in decreasing energy intake need to be established...
  44. ncbi Flavour-nutrient learning in humans: an elusive phenomenon?
    Martin R Yeomans
    School of Psychology, University of Sussex, Brighton, UK
    Physiol Behav 106:345-55. 2012
    ....
  45. pmc Vagal and hormonal gut-brain communication: from satiation to satisfaction
    H R Berthoud
    Neurobiology of Nutrition Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Neurogastroenterol Motil 20:64-72. 2008
    ..sends information to the brain regarding the quality and quantity of ingested nutrients, not only important for satiation and meal termination, but also for the appetitive phase of ingestive behaviour and the patterning of meals ..
  46. ncbi Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial
    M Maersk
    Department of Internal Medicine and Endocrinology MEA, Aarhus University Hospital, Aarhus C, Denmark
    Eur J Clin Nutr 66:523-9. 2012
    ....
  47. ncbi Peripheral glucagon-like peptide-1 (GLP-1) and satiation
    Mukesh Punjabi
    Physiology and Behaviour Laboratory, Institute of Food, Nutrition and Health, ETH Zurich, 8603 Schwerzenbach, Switzerland
    Physiol Behav 105:71-6. 2011
    ..in two different sites to inhibit eating, they argue against a role of systemic increases in endogenous GLP-1 in satiation in chow-fed rats...
  48. ncbi The effect of different dosages of guar gum on gastric emptying and small intestinal transit of a consumed semisolid meal
    M A van Nieuwenhoven
    Department of Gastroenterology, Maastricht University, The Netherlands
    J Am Coll Nutr 20:87-91. 2001
    ..There is no consensus about the effect of guar gum supplementation on gastrointestinal transit. It has been suggested that guar gum slows gastric emptying and intestinal transit, thus inducing an increased feeling of satiety...
  49. pmc Leptin reverses declines in satiation in weight-reduced obese humans
    Harry R Kissileff
    St Luke s Roosevelt Hospital Medical Center, New York, NY, USA
    Am J Clin Nutr 95:309-17. 2012
    ..or leptin deficient have a lower energy expenditure coupled with higher hunger and disinhibition and/or delayed satiation compared with never-weight-reduced control subjects...
  50. ncbi A new dental approach for reducing food intake
    Heather M Walden
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Obes Res 12:1773-80. 2004
    ..This removable tool is inserted into the upper palate of the mouth, reducing the size of the oral cavity, thereby potentially reducing bite size...
  51. ncbi Sensitivity of ad libitum meals to detect changes in hunger. Restricted-item or multi-item testmeals in the design of preload appetite studies
    Katy R Wiessing
    Human Nutrition Unit, University of Auckland, 18 Carrick Place, Mount Eden, Auckland, New Zealand
    Appetite 58:1076-82. 2012
    ..1% compensation; M(I): -993 kJ, 28.4% compensation). In preload studies measuring EI, increasing the variety of an ad lib testmeal may not decrease the sensitivity to detect changes in hunger and fullness...
  52. ncbi Does the consumption of caloric and non-caloric beverages with a meal affect energy intake?
    Diane M DellaValle
    Department of Nutritional Sciences, The Pennsylvania State University, 226 Henderson Building, University Park, PA 16802 6502, USA
    Appetite 44:187-93. 2005
    ..These results show that when caloric beverages are consumed with a meal they add to energy intake from food, without significantly affecting satiety ratings...
  53. pmc Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats
    Guillaume de Lartigue
    Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
    PLoS ONE 7:e32967. 2012
    ..We tested the hypothesis that leptin resistance in VAN is responsible for reducing CCK signaling and satiation.
  54. ncbi Satiety-relevant sensory qualities enhance the satiating effects of mixed carbohydrate-protein preloads
    Martin R Yeomans
    School of Psychology, University of Sussex, Brighton, United Kingdom
    Am J Clin Nutr 94:1410-7. 2011
    Orosensory cues such as food texture and flavor have been shown to play a role in satiation, but their role in satiety remains less clear.
  55. ncbi Cognitive influences on food intake: the effects of manipulating memory for recent eating
    Suzanne Higgs
    School of Psychology, University of Birmingham, Edgbaston, Birmingham, West Midlands, England, B15 2TT, United Kingdom
    Physiol Behav 94:734-9. 2008
    ..These data are consistent with evidence of hyperphagia in amnesic patients and laboratory animals with lesions to the hippocampus, an important substrate for learning and memory...
  56. pmc Children's bite size and intake of an entrée are greater with large portions than with age-appropriate or self-selected portions
    Jennifer Orlet Fisher
    US Department of Agriculture Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Clin Nutr 77:1164-70. 2003
    ..Whether large portion sizes affect children's eating behavior has rarely been studied...
  57. ncbi Acute effects of complexity in aroma composition on satiation and food intake
    Rianne M A J Ruijschop
    NIZO Food Research, Kernhemseweg 2, PO Box 20, 6710 BA Ede, The Netherlands
    Chem Senses 35:91-100. 2010
    The acute effect of complexity in aroma composition on perceived satiation and food intake was investigated in 41 young, healthy, and normal weight subjects...
  58. ncbi "Are you done?" Child care providers' verbal communication at mealtimes that reinforce or hinder children's internal cues of hunger and satiation
    Samantha A Ramsay
    Department of Family and Consumer Sciences, University of Idaho, Coeur d Alene, ID 83814, USA
    J Nutr Educ Behav 42:265-70. 2010
    To explore the verbal communication of child care providers regarding preschool children's internal and non-internal hunger and satiation cues.
  59. ncbi Liquid calories and the failure of satiety: how good is the evidence?
    E Almiron-Roig
    Nutritional Sciences Program, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
    Obes Rev 4:201-12. 2003
    ..Such factors appear to interact with pre-load texture in their impact on hunger and satiety and later food consumption...
  60. ncbi A role for NPY overexpression in the dorsomedial hypothalamus in hyperphagia and obesity of OLETF rats
    S Bi
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Am J Physiol Regul Integr Comp Physiol 281:R254-60. 2001
    ..A similar DMH NPY overexpression was evident in 5-wk-old preobese OLETF rats. These findings suggest a role for DMH NPY upregulation in the etiology of OLETF hyperphagia and obesity...
  61. ncbi Listening to music while eating is related to increases in people's food intake and meal duration
    Nanette Stroebele
    Department of Psychology, Georgia State University, Atlanta, GA 30303 3082, USA
    Appetite 47:285-9. 2006
    ..The presence of music appears to be one of a set of environmental factors that influences food and fluid intake in the natural world...
  62. pmc Effect of rye bread breakfasts on subjective hunger and satiety: a randomized controlled trial
    Hanna Isaksson
    Department of Food Science, Swedish University of Agricultural Sciences, SE 750 07 Uppsala, Sweden
    Nutr J 8:39. 2009
    ..The aim of the present study was to investigate subjective appetite during 8 h after intake of iso-caloric rye bread breakfasts varying in rye dietary fibre composition and content...
  63. ncbi The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats
    Shuichi Koda
    Third Department of Internal Medicine, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki 889 1692, Japan
    Endocrinology 146:2369-75. 2005
    ..This study indicates that peripheral PYY(3-36) may transmit satiety signals to the brain in part via the vagal afferent pathway...
  64. ncbi A role for glucagon-like peptide-1 in the central regulation of feeding
    M D Turton
    Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK
    Nature 379:69-72. 1996
    ..Both of these regions of the brain are of primary importance in the regulation of feeding. These findings suggest that central GLP-1 is a new physiological mediator of satiety...
  65. ncbi Relation between food intake and visual analogue scale ratings of appetite and other sensations in healthy older and young subjects
    B A Parker
    Department of Medicine, University of Adelaide, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, Australia
    Eur J Clin Nutr 58:212-8. 2004
    ..The aim of this study was to determine the relations between food intake and visual analogue scale (VAS) ratings of appetite and nonappetite sensations in healthy older and young subjects...
  66. ncbi Mastication of almonds: effects of lipid bioaccessibility, appetite, and hormone response
    Bridget A Cassady
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    Am J Clin Nutr 89:794-800. 2009
    ..This has been attributed to strong satiety properties, increased resting energy expenditure, and limited lipid bioaccessibility...
  67. ncbi The control of meal size in human subjects: a role for expected satiety, expected satiation and premeal planning
    Jeffrey M Brunstrom
    Nutrition and Behaviour Unit, School of Experimental Psychology, University of Bristol, Bristol BS8 1TU, UK
    Proc Nutr Soc 70:155-61. 2011
    ..The prevailing view is that meal size is governed by physiological and psychological events that promote satiation towards the end of a meal. This review explores an alternative and perhaps controversial proposition...
  68. ncbi Eating slowly led to decreases in energy intake within meals in healthy women
    Ana M Andrade
    Department of Nutrition and Food Sciences, University of Rhode Island, Kingston, RI 02881, USA
    J Am Diet Assoc 108:1186-91. 2008
    ..We sought to compare the impact of slow and quick eating rates on development of satiation in healthy women. In a randomized design, 30 healthy women (22.9+/-7...
  69. ncbi Palatability: response to nutritional need or need-free stimulation of appetite?
    Martin R Yeomans
    Department of Psychology, School of Life Sciences, University of Sussex, Brighton, Sussex BN1 9QG, UK
    Br J Nutr 92:S3-14. 2004
    ..This conclusion leads to the possibility of novel therapies for obesity based on modulation of hedonic rather than homeostatic controls. Potential developments are discussed...
  70. ncbi Comparison of the effects of a high-fat and high-carbohydrate soup delivered orally and intragastrically on gastric emptying, appetite, and eating behaviour
    J E Cecil
    Centre for Human Nutrition, University of Sheffield, Northern General Hospital, UK
    Physiol Behav 67:299-306. 1999
    ....
  71. ncbi Soluble fiber dextrin enhances the satiating power of beverages
    Pablo Monsivais
    Nutritional Sciences Program, School of Public Health, University of Washington, Seattle, WA 98195, USA
    Appetite 56:9-14. 2011
    ..023). Supplementing beverages with soluble fiber dextrin affects short term energy intake and may have implications for weight control...
  72. ncbi Fat as a risk factor for overconsumption: satiation, satiety, and patterns of eating
    J E Blundell
    Department of Psychology, University of Leeds, United Kingdom
    J Am Diet Assoc 97:S63-9. 1997
    ..Eating high-fat foods can facilitate the development of short-term positive energy balances by influencing satiation and satiety, the processes that control the size of eating episodes and the strength of postingestive appetite ..
  73. pmc The influence of higher protein intake and greater eating frequency on appetite control in overweight and obese men
    Heather J Leidy
    Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, Kansas, USA
    Obesity (Silver Spring) 18:1725-32. 2010
    ..Collectively, these data suggest that higher protein intake promotes satiety and challenge the concept that increasing the number of eating occasions enhances satiety in overweight and obese men...
  74. ncbi Increased leptin expression in common Carp (Cyprinus carpio) after food intake but not after fasting or feeding to satiation
    Mark O Huising
    Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands
    Endocrinology 147:5786-97. 2006
    ..Animals that were fed to satiation grew twice as fast as controls; however, they did not show increased leptin expression at the termination of the ..
  75. ncbi Effect of sensory perception of foods on appetite and food intake: a review of studies on humans
    L B Sørensen
    Department of Human Nutrition, Centre for Advanced Food Studies, The Royal Veterinary and Agricultural University, Frederiksberg C, Denmark
    Int J Obes Relat Metab Disord 27:1152-66. 2003
    ....
  76. ncbi PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humans
    Rachel L Batterham
    Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK
    Nature 450:106-9. 2007
    ..An increased understanding of how such homeostatic and higher brain functions are integrated may pave the way for the development of new treatment strategies for obesity...
  77. ncbi Effect of the glycemic index and content of indigestible carbohydrates of cereal-based breakfast meals on glucose tolerance at lunch in healthy subjects
    H G Liljeberg
    Department of Applied Nutrition and Food Chemistry, Chemical Center, Lund University, Sweden
    Am J Clin Nutr 69:647-55. 1999
    ....
  78. ncbi Volume of food consumed affects satiety in men
    B J Rolls
    Nutrition Department, Pennsylvania State University, University Park 16802 6501, USA
    Am J Clin Nutr 67:1170-7. 1998
    ..Consistent with the effects on intake, the volume of the drinks affected ratings of hunger and fullness. These results indicate that the volume consumed is an important determinant of satiety after milk drinks under these conditions...
  79. ncbi Dietary fiber and weight regulation
    N C Howarth
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Nutr Rev 59:129-39. 2001
    ..e., approximately half the American Heart Association recommendation of 25-30 g/day), efforts to increase dietary fiber in individuals consuming <25 g/day may help to decrease the currently high national prevalence of obesity...
  80. ncbi Eating for pleasure or just wanting to eat? Reconsidering sensory hedonic responses as a driver of obesity
    David J Mela
    Unilever Food and Health Research Institute, Vlaardingen, The Netherlands
    Appetite 47:10-7. 2006
    ..This distinction may have important implications for further research, and applications in commercial and public health approaches to modifying energy intakes...
  81. ncbi Learning at different satiation levels reveals parallel functions for the cAMP-protein kinase A cascade in formation of long-term memory
    Anke Friedrich
    Institut für Biologie Neurobiologie, Freie Universitat Berlin, 14195 Berlin, Germany
    J Neurosci 24:4460-8. 2004
    ..of the cAMP-dependent protein kinase A (PKA), a key player in LTM formation, differs in animals with different satiation levels...
  82. ncbi Palatability affects satiation but not satiety
    C de Graaf
    Department of Human Nutrition and Epidemiology, Wageningen Taste and Smell Centre, Wageningen Agricultural University, The Netherlands
    Physiol Behav 66:681-8. 1999
    The present study was designed to investigate the effect of the pleasantness of a food on satiation (meal termination) and satiety...
  83. ncbi The relationship between food reward and satiation revisited
    Anthony Sclafani
    Department of Psychology, Brooklyn College, Brooklyn, NY 11210 2889, USA
    Physiol Behav 82:89-95. 2004
    ..Food intake and preference are controlled by a complex interaction of positive and negative signals generated by nutrients in the mouth and at postingestive sites...
  84. ncbi Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin
    J H Peters
    Department of Veterinary and Comparative Anatomy, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 6520, USA
    Endocrinology 145:3652-7. 2004
    ..Acute activation of vagal afferents by leptin alone and in combination with CCK may contribute to modulation of visceral reflexes and control of food intake...
  85. pmc Walnut consumption increases satiation but has no effect on insulin resistance or the metabolic profile over a 4-day period
    Aoife M Brennan
    Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 18:1176-82. 2010
    ..It has been proposed, mainly on the basis of observational studies, that nuts may provide superior satiation, may lead to reduced calorie consumption, and may decrease the risk of type 2 diabetes; but evidence from ..
  86. ncbi Clarifying concepts about macronutrients' effects on satiation and satiety
    Dana E Gerstein
    Center for Weight and Health, University of California, Berkeley, USA
    J Am Diet Assoc 104:1151-3. 2004
    ..The objective of this article is to define the terminology commonly used to discuss the macronutrients' roles in appetite regulation and to discuss the interrelated concepts and roles of taste, palatability, and energy density...
  87. ncbi Children's familiarity with snack foods changes expectations about fullness
    Charlotte A Hardman
    Nutrition and Behaviour Unit, School of Experimental Psychology, University of Bristol, United Kingdom
    Am J Clin Nutr 94:1196-201. 2011
    ..In adults, there is emerging evidence that expectations about the satiating properties of foods are an important determinant of meal size, and these beliefs are learned...
  88. ncbi The paradox of satiation
    George Collier
    Rutgers, The State University of New Jersey, NJ 08854, USA
    Physiol Behav 82:149-53. 2004
    Animals behave in bouts, and the process that causes feeding bouts to end is called satiation. Bout size or, in the case of feeding, meal size is the result both of the costs of food resources and the consequences of consuming a ..
  89. ncbi Nutrient sensing in the gut: interactions between chemosensory cells, visceral afferents and the secretion of satiation peptides
    Robert E Steinert
    Clinical Research Center, Department of Biomedicine and Division of Gastroenterology, University Hospital Basel, Basel, Switzerland
    Physiol Behav 105:62-70. 2011
    ..a brief overview on gastrointestinal chemosensory mechanisms and their functional involvement in the secretion of satiation peptides with a focus on human studies albeit most evidence at present comes from in vitro or animal studies.
  90. ncbi Effects of asimadoline, a kappa-opioid agonist, on satiation and postprandial symptoms in health
    S Delgado-Aros
    Clinical Enteric Neuroscience Translational and Epidemiological Research CENTER Program, Mayo Clinic, Rochester, MN 55905, USA
    Aliment Pharmacol Ther 18:507-14. 2003
    To evaluate the effect of single administrations of asimadoline, a kappa-opioid agonist, on satiation volume, postprandial symptoms and gastric volumes.
  91. ncbi Effect of time of consumption of preloads on measures of satiety in healthy normal weight women
    Sylvia M S Chungchunlam
    Riddet Institute, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand
    Appetite 59:281-8. 2012
    ..Subjective ratings of appetite did not support a greater satiating effect of whey protein versus maltodextrin on food intake but there was evidence for a satiating effect of maltodextrin and whey protein versus the water control...
  92. ncbi An investigation of the role of oro-sensory stimulation in sugar satiety?
    J H Lavin
    Slimming World, Clover Nook Road, Alfreton, Derbyshire, UK
    Int J Obes Relat Metab Disord 26:384-8. 2002
    ..To investigate whether oral factors stimulated by the presence of sucrose in the mouth are involved in the suppression of appetite following sucrose ingestion...
  93. ncbi Eating rate during a fixed-portion meal does not affect postprandial appetite and gut peptides or energy intake during a subsequent meal
    J Philip Karl
    Military Nutrition Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Physiol Behav 102:524-31. 2011
    ..Ad libitum energy intake was not different between trials. In conclusion, the rate at which a fixed-portion meal is consumed does not appear to alter satiety despite a small effect on PP and CCK responses...
  94. ncbi Accelerated satiation after duodenal switch
    Picard Marceau
    Department of Surgery, Laval University, Quebec, Canada
    Surg Obes Relat Dis 1:408-12. 2005
    This is to introduce a new test "negative alliesthesia" for measuring satiation after bariatric surgery. It is a test that is well known by physiologists but has never been used clinically...
  95. ncbi Inhibition of food intake induced by acute stress in rats is due to satiation effects
    J Calvez
    INRA, UMR914 Nutrition Physiology and Ingestive Behavior, F 75005 Paris, France
    Physiol Behav 104:675-83. 2011
    ..These results suggest that acute stress may affect ingestive behavior by increasing satiation and to some extent by enhancing grooming, and this may be due to stimulation of the hypothalamic POMC neurons.
  96. ncbi Are caloric beverages compensated for in the short-term by young adults? An investigation with particular focus on gender differences
    D V Ranawana
    Functional Food Centre, Oxford Brookes University, United Kingdom
    Appetite 55:137-46. 2010
    ..On the other hand, females appeared to show a possible dysregulation, which requires further investigation...
  97. pmc Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency
    Jennifer R McDuffie
    Unit on Growth and Obesity, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1862, USA
    J Clin Endocrinol Metab 89:4258-63. 2004
    To examine leptin's role in human appetite regulation, we studied recombinant methionyl human leptin's effects on satiation and satiety in a model of leptin insufficiency, lipodystrophy...
  98. ncbi Deficits in gastrointestinal responses controlling food intake and body weight
    Mihai Covasa
    L Institute National de la Recherche Agronomique, Centre de Recherche, Microbiologie de l Alimentation au service de la Santé Humaine MICALIS, Neurobiology of Ingestive Behavior, Jouy en Josas, France
    Am J Physiol Regul Integr Comp Physiol 299:R1423-39. 2010
    ..It focuses on changes in sensitivity to satiation signals resulting from chronic ingestion of high-fat diet, which may lead to disordered appetite and ..
  99. ncbi Conditioning 'fullness expectations' in a novel dessert
    Laura L Wilkinson
    Department of Experimental Psychology, University of Bristol, Bristol, England, United Kingdom
    Appetite 52:780-3. 2009
    Calorie-for-calorie, foods differ considerably in the extent to which they are expected to deliver satiation. We sought to demonstrate that flavour-nutrient learning modifies these expectations...
  100. ncbi Short-term regulation of food intake in children, young adults and the elderly
    E H Zandstra
    Division of Human Nutrition and Epidemiology, Wageningen University, Dreijenlaan 1 BODE 154, 6703 HA Wageningen, The Netherlands
    Eur J Clin Nutr 54:239-46. 2000
    ..The present study investigated the effects of consuming preloads with different macronutrient and energy contents on subsequent intake and subjective feelings of hunger and satiety in children, young adults and the elderly...
  101. ncbi Eating behavior in humans, characterized by cumulative food intake curves--a review
    M S Westerterp-Plantenga
    Department of Human Biology, Maastricht University, The Netherlands
    Neurosci Biobehav Rev 24:239-48. 2000
    ..characteristics dietary restraint and obesity; show a clear relationship with the physiological parameters satiation, diet-induced thermogenesis and body-temperature near the liver, and with the cognitive parameter: estimating ..

Research Grants63

  1. Neural Functioning of Feeding Centers in Obese Youth
    ROBERT STANLEY SHERWIN; Fiscal Year: 2013
    ..little investigation has been done in adolescents to understand the neural circuitry underlying hunger and satiation. Even more important, virtually no studies, to our knowledge, have yet been done to understand how these neural ..
  2. Intestinal satiation in Roux-en-Y gastric bypass rats: brain mechanisms and sex d
    Thomas Alexander Lutz; Fiscal Year: 2013
    ..The mechanisms through which RYGB increases satiation and reduces eating and body adiposity are poorly understood...
  3. NEURAL HIERARCHY IN THE MODULATION OF INGESTIVE BEHAVIOR
    Harvey J Grill; Fiscal Year: 2013
    ..of different physiological signals, such as the adipose tissue-derived hormone leptin and gastrointestinal (GI) satiation signals...
  4. Neuroendocrinology of Energy Balance Control
    Matthew R Hayes; Fiscal Year: 2013
    ..immunohistochemical, electrophysiological, and advanced surgical techniques to examine: [1] whether vagal satiation signals from the gastrointestinal tract inhibit food intake in part via mediation by NTS GLP-1 projections to ..
  5. Motivational Changes for Nutritionally Relevant Tastes after Gastric Bypass
    Alan C Spector; Fiscal Year: 2013
    ..behavior and is designed for applications in which the reinforcer delivery needs to be limited to obviate satiation. As such, itis well suited for assessing changes in the reward value of simple and complex taste stimuli after ..
  6. Pharmacogenomics of Gastric Function &Weight in Obesity
    MICHAEL L CAMILLERI; Fiscal Year: 2013
    ..studies (uncoupling proteins [UCP], and FTO, and type II DM [TCF7L2]) on peripheral determinants of satiation and satiety though validated measurements of gastric emptying of solids and liquids by scintigraphy, gastric ..
  7. The GE PETtrace Cyclotron: A Scientific Resource for the State of Arizona
    Eric M Reiman; Fiscal Year: 2010
    ..made major contributions to the study of memory, consciousness, emotion, temperature and pain sensation, hunger, satiation, taste and the predisposition to obesity, the role of PET in clinical oncology, the role of brain-mapping in ..
  8. Antidepressant Therapy for Functional Dyspepsia
    YURI ANN SAITO LOFTUS; Fiscal Year: 2011
    ..2) Acceleration of solid gastric emptying, reduction of postprandial satiation and enhanced gastric volume change with a meal on antidepressant therapy will be significant positive predictors ..
  9. Brain apoA-IV Mediates Estrogenic Reduction of Dietary Obesity in Female Rats
    Stephen C Woods; Fiscal Year: 2013
    ..Apolipoprotein A-IV (apoA-IV), an important satiation factor, is a compelling candidate in this regard...
  10. NUCLEUS TRACTUS SOLITARIUS MELANOCORTIN SIGNALING IN THE CONTROL OF FOOD INTAKE
    SCOTT EDWARD KANOSKI; Fiscal Year: 2012
    ..signaling is required for food intake suppression by exogenous cholecystokinin (CCK), the intestinally-derived satiation hormone...
  11. Food intake and energy metabolism regulated by apo AIV and CCK
    Chunmin C Lo; Fiscal Year: 2013
    ..The potency of satiation in response to CCK is reduced by maintenance on a high-fat diet (HFD)...
  12. NTS neurons integrate leptin and satiation signals to influence reward signaling
    AMBER ALHADEFF; Fiscal Year: 2013
    ..caudal brainstem is necessary for the control of food intake, body weight, and processing of vagally-derived GI satiation signals, and recently it has also been implicated in the regulation of food-motivated and appetitive behaviors...
  13. Impact of diet composition during infancy on energy balance, satiety and growth
    JILLIAN CHRISTINE TRABULSI; Fiscal Year: 2013
    ..are 3, 12, and 24 months, they will be videotaped while feeding their assigned formula, or solid foods, to satiation during child-led feeding sessions, after which biomarkers of satiation and satiety (active GLP-1 and ghrelin, ..
  14. Mechanisms of S6K1 Mediated Insulin Resistance
    George Thomas; Fiscal Year: 2010
    ..This negative role is revealed under conditions of nutrient satiation and is most likely mediated through the phosphorylation of specific residues on insulin receptor substrate 1 (..
  15. Carbohydrate Appetite, Fat Appetite and Obesity
    Anthony Sclafani; Fiscal Year: 2013
    ..The onset of satiation during meals can mask the initial stimulation of intake by post-oral nutrients, which has hindered the study of ..
  16. Neural mechanisms controlling food intake and body weight after bariatric surgery
    Hans Rudolf Berthoud; Fiscal Year: 2013
    ..of the brain is directly connected with the gut by the vagus nerve and intimately involved in the control of satiation and meal size...
  17. Neuroendocrine Integration of Satiety and Food Reward
    Diana L Williams; Fiscal Year: 2013
    ..investigates the neural circuitry that integrate the rewarding value of food with input from gut-derived satiation and satiety signals, and will address the physiological relevance of these circuits for the control of food ..
  18. ENVIRONMENTAL AND PHARMACOLOGICAL CONTROL OF DRUG ABUSE
    Marilyn Carroll; Fiscal Year: 2000
    ..Some groups of 5 rats will have behavioral interventions such as food satiation, food deprivation or access to an alternative reinforcer such as orally-delivered G+S or ethanol (8%)...
  19. Physiologic Effects of High-Dose Gastric Antral Botulinum Toxin Injections
    Mark D Topazian; Fiscal Year: 2010
    ..Our long-term objective is to determine whether alterations in gastric function can increase satiation, decrease caloric intake, and cause body weight reduction without other adverse gastrointestinal symptoms...
  20. A Physiological Role of Gastrin Releasing Peptide in the Control of Meal Size
    Ayman I Sayegh; Fiscal Year: 2013
    ..4) The vagus and / or the sympathetic nerves have a role in transmitting the GRP-satiation signal from the enteric neurons to the hindbrain.
  21. Genetic and food advertisement influences on eating without hunger in children
    DIANE IHN AE GILBERT-DIAMOND; Fiscal Year: 2013
    ..children will consume highly palatable food when it is presented to them immediately after they have eaten to satiation. The extent of this behavior, eating in the absence of hunger (EAH), has been strongly associated with ..
  22. Apolipoprotein AIV regulates CCK secretion and potentiates CCK-induced satiation
    Chunmin C Lo; Fiscal Year: 2013
    ..This will provide a novel concept for generating pharmacological approaches to influence food intake and body weight. ..
  23. The role of the amygdala in weight gain susceptibility
    Dana M Small; Fiscal Year: 2013
    ..project are as follows: (1) To determine whether changes in amygdala responses to food stimuli following satiation are altered in overweight/obese human subjects, and whether such abnormal responses function as predictors of ..
  24. The Role of Glutamate in the Control of Food Intake
    Robert C Ritter; Fiscal Year: 2013
    ..Hence, GI signals drive satiation, and are seminal to control of food intake, regardless of the conditions that initiate it...
  25. ACTIONS OF PERIPHERAL 5-HYDROXYTRYPTAMINE IN FEEDING
    Kenny Simansky; Fiscal Year: 2000
    ..in the gastrointestinal system and pathways for neuronal processing of the peripheral serotonergic signal for satiation. The proposed investigation tests specific hypotheses about the nature of the primary target sites in the ..
  26. PRINCIPLES OF REINFORCEMENT
    Peter Killeen; Fiscal Year: 2001
    ..for conditions of varying motivation, such as those occurring in closed economies and contexts where warm-up and satiation play significant roles...
  27. Neural Mechanisms of Overeating in Prader-Willi Syndrome
    Anastasia Dimitropoulos; Fiscal Year: 2009
    ..satiety response but also by abnormally heightened responses to rewarding food during hunger and after attempted satiation. PWS is characterized by an insatiable appetite associated with excessive overeating, propensity to obesity, ..
  28. Primary Prevention of Weight Gain for Women Aged 25-45
    Walter Willett; Fiscal Year: 2004
    ..with beans and it has been suggested that the consumption of low-GI diets may: 1) decrease hunger/ increase satiation; 2) reduce lipogenesis...
  29. Influence of Smoking Abstinence and Age on ERP Indices of Attentional Control
    David J Drobes; Fiscal Year: 2010
    ..The primary aim of the proposed research is to examine effects of nicotine satiation versus withdrawal on cognitive-attentional performance among heavy smokers as a function of the normal aging ..
  30. Food Rheology and Exercise in Aging Humans
    WAYNE CAMPBELL; Fiscal Year: 2009
    ..Study 1 will contrast the acute effects of fluid and solid food ingestion, coupled with RE, on satiation, satiety, and feeding...
  31. Translating Habituation Research to Interventions for Pediatric Obesity
    Leonard H Epstein; Fiscal Year: 2013
    ..RELEVANCE Habituation is a theoretically rich behavioral science area that is important to satiation and energy intake regulation...
  32. Mechanism of Estrogen's Inhibitory Effects on Feeding
    LISA ECKEL; Fiscal Year: 2004
    ..known whether changes in endogenous estrogen activity mediate the decrease in food intake and increase in CCK satiation expressed during estrus in cycling rats...
  33. CNS CCK IN APPETITIVE AND CONSUMMATORY FOOD MOTIVATION
    ELIOT STELLAR; Fiscal Year: 1991
    ..p.) and central (intracerebroventricular or ICV) effects on satiation and on food rewards (1,2)...
  34. NEUROPEPTIDES AND SALT APPETITE
    FRANCIS FLYNN; Fiscal Year: 2007
    ..hypothesis that NKB-expressing and NK3 receptor expressing neurons are activated during the normal inhibition (satiation) of salt appetite...
  35. Gustatory Processing and Satiety
    Sidney A Simon; Fiscal Year: 2010
    ..e.hunger, satiation) can be more accurately obtained if neuronal information from the above mentioned brain areas are acquired ..
  36. Effects of Leptin on Body Weight and Neuroendocrine Axes after Gastric Bypass
    Judith Korner; Fiscal Year: 2009
    ..GLP-1 acts synergistically with leptin to cause greater satiation and decreased food intake in animals...
  37. Genes underlying food-related behaviors in Drosphila.
    MARLA SOKOLOWSKI; Fiscal Year: 2007
    ..This imbalance between energy input and output is in part mediated by inappropriate responses to hunger and satiation. We propose to develop an obesity model using the Drosophila larva that will enable us to rapidly identify, ..
  38. Hepatic Metabolic Control of Meal Size and Number
    Wolfgang Langhans; Fiscal Year: 2007
    ..e., produce satiation)...
  39. ASSOCIATIVE FUNCTIONS OF THE BASOLATERAL AMYGDALA
    Michela Gallagher; Fiscal Year: 2009
    ..signaled the availability of food when animals were hungry, augment food consumption in subsequent tests when satiation and replete energy stores...
  40. Serotonin and Stimulus Control of Ingestive Responses
    Kenny Simansky; Fiscal Year: 2005
    ..Stimulating 5-HT1B receptors promotes satiation in rabbits...
  41. INCREASING THE REINFORCING EFFECTIVENESS OF ETHANOL
    HENRY MARCUCELLA; Fiscal Year: 1980
    ..and non-availability periods affects the delay of reinforcement, and the dosage of ethanol affects the rate of satiation. Therefore, the effects of these variables on the amount of ethanol consumed and the development of ethanol as a ..
  42. UNDERSTANDING DESTRUCTIVE BEHAVIOR IN CHILDREN
    Jennifer McComas; Fiscal Year: 1999
    ..One of the most important Eos related to destructive behavior for children is deprivation/satiation of adult attention...
  43. Influence of reward devaluation on striatal activity
    HOWARD CROMWELL; Fiscal Year: 2003
    ..in vivo electrophysiological recording of single striatal neurons while animals under different states of food satiation and deprivation perform instrumental discrimination tasks for different rewards...
  44. SEMANTIC SATIATION, LEXICAL AMBIGUITY AND AGE
    Sheila Black; Fiscal Year: 1992
    Semantic satiation refers to the attenuation in the meaning of a word that occurs as a result of excessive exposure to the word...
  45. THE SATIATION OF HUNGER
    HENRY KOOPMANS; Fiscal Year: 1980
    ..Finally, the importance of the lower digestive tract in feeding behavior will be investigated by transposing a segment to ileum to the duodenum of rats. ..
  46. ORAL, GASTRIC AND POSTGASTRIC CONTRIBUTIONS TO SATIETY
    Joel Kaplan; Fiscal Year: 2005
    ..and spacing) into explicit register, to evaluate the relative weightings of gastric and post-gastric sources to satiation and satiety, we will characterize ingestive responses to manipulation that systematically bias the accumulation ..
  47. NEURON EXCITABILITY REGULATION IN A HOMEOSTATIC PATHWAY
    Rhanor Gillette; Fiscal Year: 2003
    ..NOS activity varies with satiation state, acting like a homeostatic regulator of feeding behavior...
  48. The amygdala's role in socioemotional behavior
    LAURIE WELLMAN; Fiscal Year: 2005
    ..task, the preference for objects rewarded by two different food rewards, one of which was devalued by selective satiation ("reinforcer devaluation effect"). This task has been previously shown to be sensitive to A damage...
  49. ALPHA 2 ADRENERGIC CONTROL IN IRRITABLE BOWEL SYNDROME
    Michael Camilleri; Fiscal Year: 2008
    ..Significance: This project will characterize pharmacogenetic mechanisms determining the response to clonidine through studies of candidate genes that control alpha2-adrenoreceptor function and norepinephrine transport in IBS. ..
  50. Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory Functions
    MICHAEL L CAMILLERI; Fiscal Year: 2010
    ..this lab show that a CBR agonist, dronabinol, inhibits gastric and colonic motility, which may alter appetite or satiation in obesity, and may have potential in the treatment of IBS...
  51. ALPHA-2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBS
    Michael Camilleri; Fiscal Year: 2007
    ..abstract_text> ..
  52. FACTORS AFFECTING CALORIC REGULATION IN HUMAN FEEDING
    Barbara Rolls; Fiscal Year: 2007
    ..The experiments carefully vary fat content while keeping the energy content constant or vice versa, all while maintaining constant palatability. ..
  53. Neuropharmacology of Learned Food Preferences
    Anthony Sclafani; Fiscal Year: 2009
    ..It will advance our understanding of the basic mechanisms involved in the development of food preferences and may provide insights into the clinical treatment of overeating and obesity. ..
  54. Food Rheology and Feeding in Lean and Obese Humans
    Richard Mattes; Fiscal Year: 2007
    ..Study 1 will contrast the acute effects of fluid and solid foods varying in macronutrient content on satiation, satiety and feeding...
  55. FUNCTIONAL ORGANIZATION OF THE VAGAL-ENTERIC INTERFACE
    Hans Rudolf Berthoud; Fiscal Year: 2003
    ..abstract_text> ..
  56. Non-Homeostatic Neural Controls of Food Intake
    Hans Rudolf Berthoud; Fiscal Year: 2010
    ..abstract_text> ..
  57. CEPHALIC RESPONSES AND MEAL FEEDING
    Stephen Woods; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  58. HEDONICS AND DIETARY INTAKE OF FAT
    Richard Mattes; Fiscal Year: 2008
    ..This will be explored through stable isotope tracer studies for Aim 3. The proposed work will hold important public health, clinical, commercial and basic biological implications. [unreadable] [unreadable]..
  59. An Exploratory Center for Obesity Research (RMI)
    Adam Drewnowski; Fiscal Year: 2006
    ..By promoting interagency collaborations, these efforts will help the NIH develop a roadmap on how to effectively translate research findings into national, state, and local health policy. [unreadable] [unreadable]..
  60. Genetic remodeling of Vagal Afferent Organization
    Edward Fox; Fiscal Year: 2009
    ..Moreover, it will form an essential foundation for further research on the development of, and the structural and functional organization of, the diverse systems that form the vagal sensorium. ..
  61. OVARIAN HORMONAL CONTROL OF MEAL SIZE
    NORCROSS GEARY; Fiscal Year: 2008
    ..There are eight specific aims: (1) Determine whether estradiol tonically or phasically increases gastric satiation, using rats with inflatable pyloric cuffs...
  62. Metabolic and Epigenetic Effects of Maternal High Fat Diet in Obesity Prone Rats
    Timothy H Moran; Fiscal Year: 2010
    ..The results of these experiments will enhance our understanding of the etiology of obesity and metabolic disease ultimately allowing the development of rational clinical interventions for such conditions. ..
  63. Society for the Study of Ingestive Behavior Annual Meet
    Timothy Moran; Fiscal Year: 2003
    ..abstract_text> ..