object attachment

Summary

Summary: Emotional attachment to someone or something in the environment.

Top Publications

  1. ncbi Less is more: meta-analyses of sensitivity and attachment interventions in early childhood
    Marian J Bakermans-Kranenburg
    Center for Child and Family Studies, Leiden University, The Netherlands
    Psychol Bull 129:195-215. 2003
  2. doi Maternal attachment representations after very preterm birth and the effect of early intervention
    Dominique Meijssen
    Developmental Psychology, Tilburg University, Tilburg, The Netherlands
    Infant Behav Dev 34:72-80. 2011
  3. ncbi Mothers in the NICU: outsider to partner
    Judith A Heermann
    The College of Nursing, University of Nebraska Medical Center, Omaha, NE, USA
    Pediatr Nurs 31:176-81, 200. 2005
  4. ncbi Maternal reflective functioning, mother-infant affective communication, and infant attachment: exploring the link between mental states and observed caregiving behavior in the intergenerational transmission of attachment
    John F Grienenberger
    Wright Institute, 11340 W Olympic Boulevard, Ste 245, Los Angeles, CA 90064, USA
    Attach Hum Dev 7:299-311. 2005
  5. doi A comparison of mothers' and fathers' experiences of the attachment process in a neonatal intensive care unit
    Liv Fegran
    Faculty of Health and Sports, University of Agder, Norway
    J Clin Nurs 17:810-6. 2008
  6. pmc The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction
    James P Burkett
    Center for Translational Social Neuroscience, Division of Behavioral Neuroscience and Psychiatric Disorders, Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, 954 Gatewood Road, Atlanta, GA 30329, USA
    Psychopharmacology (Berl) 224:1-26. 2012
  7. ncbi The nature of the mother's tie to her infant: maternal bonding under conditions of proximity, separation, and potential loss
    R Feldman
    Department of Psychology, Bar Ilan University, Ramat Gan, Israel
    J Child Psychol Psychiatry 40:929-39. 1999
  8. doi The significance of insecure attachment and disorganization in the development of children's externalizing behavior: a meta-analytic study
    R Pasco Fearon
    School of Psychology and Clinical Language Sciences, University of Reading, 3 Earley Gate, Whiteknights, Reading RD6 6AL, United Kingdom
    Child Dev 81:435-56. 2010
  9. ncbi Working models of attachment: implications for explanation, emotion and behavior
    N L Collins
    Department of Psychology, State University of New York, Buffalo 14260 4110, USA
    J Pers Soc Psychol 71:810-32. 1996
  10. ncbi Stress and accessibility of proximity-related thoughts: exploring the normative and intraindividual components of attachment theory
    M Mikulincer
    Department of Psychology, Bar Ilan University, Ramat Gan, Israel
    J Pers Soc Psychol 78:509-23. 2000

Research Grants

  1. Infant Screening and Diagnosis of Duchenne Muscular Dys*
    Paul Fernhoff; Fiscal Year: 2007
  2. KINETICS OF DRUG MACROMOLECULE COMPLEX FORMATION
    PALMER WILLIAM TAYLOR; Fiscal Year: 2013
  3. Jay R Winkler; Fiscal Year: 2016
  4. Yi Lu; Fiscal Year: 2016
  5. SIMULATION OF PROTON AND HYDRIDE TRANSFER IN ENZYMES
    Sharon Hammes Schiffer; Fiscal Year: 2010
  6. Computational Design of Small Molecule Drugs Inhibiting the Zinc Finger Transcrip
    David Sherris; Fiscal Year: 2010
  7. BLOOD PRESSURE REGULATION, STRESS AND MATERNAL OXYTOCIN RESPONSE
    Kathleen C Light; Fiscal Year: 2010
  8. RNA Modification Enzymes: Methyltransferase/psi-synthase
    Robert M Stroud; Fiscal Year: 2012
  9. Shaojie Zhang; Fiscal Year: 2014
  10. Roger L Papke; Fiscal Year: 2016

Detail Information

Publications298 found, 100 shown here

  1. ncbi Less is more: meta-analyses of sensitivity and attachment interventions in early childhood
    Marian J Bakermans-Kranenburg
    Center for Child and Family Studies, Leiden University, The Netherlands
    Psychol Bull 129:195-215. 2003
    ..Interventions that were more effective in enhancing parental sensitivity were also more effective in enhancing attachment security, which supports the notion of a causal role of sensitivity in shaping attachment...
  2. doi Maternal attachment representations after very preterm birth and the effect of early intervention
    Dominique Meijssen
    Developmental Psychology, Tilburg University, Tilburg, The Netherlands
    Infant Behav Dev 34:72-80. 2011
    ..The IBAIP is designed to assist parents to support and enhance their infant's regulatory competence and development. The intervention consisted of 6-8 home visits during the first 8 months after birth...
  3. ncbi Mothers in the NICU: outsider to partner
    Judith A Heermann
    The College of Nursing, University of Nebraska Medical Center, Omaha, NE, USA
    Pediatr Nurs 31:176-81, 200. 2005
    ..Mothers' development evolved in predictable patterns. The results of this study can be considered in implementation and evaluation plans for NICUs moving to family-focused developmental care...
  4. ncbi Maternal reflective functioning, mother-infant affective communication, and infant attachment: exploring the link between mental states and observed caregiving behavior in the intergenerational transmission of attachment
    John F Grienenberger
    Wright Institute, 11340 W Olympic Boulevard, Ste 245, Los Angeles, CA 90064, USA
    Attach Hum Dev 7:299-311. 2005
    ..A linear regression analysis indicated that maternal behavior mediates the impact of maternal reflective functioning upon infant attachment. Implications for attachment theory and early intervention are explored...
  5. doi A comparison of mothers' and fathers' experiences of the attachment process in a neonatal intensive care unit
    Liv Fegran
    Faculty of Health and Sports, University of Agder, Norway
    J Clin Nurs 17:810-6. 2008
    ..To compare mothers' and fathers' individual views and experiences of the attachment process in a neonatal intensive care unit within the first week after a premature birth...
  6. pmc The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction
    James P Burkett
    Center for Translational Social Neuroscience, Division of Behavioral Neuroscience and Psychiatric Disorders, Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, 954 Gatewood Road, Atlanta, GA 30329, USA
    Psychopharmacology (Berl) 224:1-26. 2012
    ..Brain systems that evolved to govern attachments between parents and children and between monogamous partners may be the targets of drugs of abuse and serve as the basis for addiction processes...
  7. ncbi The nature of the mother's tie to her infant: maternal bonding under conditions of proximity, separation, and potential loss
    R Feldman
    Department of Psychology, Bar Ilan University, Ramat Gan, Israel
    J Child Psychol Psychiatry 40:929-39. 1999
    ..Discussion focused on the comparability of maternal and infant attachment in relation to the neurobiological system underlying bond formation...
  8. doi The significance of insecure attachment and disorganization in the development of children's externalizing behavior: a meta-analytic study
    R Pasco Fearon
    School of Psychology and Clinical Language Sciences, University of Reading, 3 Earley Gate, Whiteknights, Reading RD6 6AL, United Kingdom
    Child Dev 81:435-56. 2010
    ..34, 95% CI: 0.18, 0.50), with weaker effects for avoidance (d = 0.12, 95% CI: 0.03, 0.21) and resistance (d = 0.11, 95% CI: -0.04, 0.26). The results are discussed in terms of the potential significance of attachment for mental health...
  9. ncbi Working models of attachment: implications for explanation, emotion and behavior
    N L Collins
    Department of Psychology, State University of New York, Buffalo 14260 4110, USA
    J Pers Soc Psychol 71:810-32. 1996
    ..These findings are consistent with the idea that adults with different working models of attachment are predisposed to think, feel, and behave differently in their relationships...
  10. ncbi Stress and accessibility of proximity-related thoughts: exploring the normative and intraindividual components of attachment theory
    M Mikulincer
    Department of Psychology, Bar Ilan University, Ramat Gan, Israel
    J Pers Soc Psychol 78:509-23. 2000
    ..However, they showed no accessibility to proximity worries even after the priming of a semantically related word and reacted with high accessibility to these worries upon the addition of cognitive load...
  11. ncbi The patient-provider relationship: attachment theory and adherence to treatment in diabetes
    P S Ciechanowski
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA
    Am J Psychiatry 158:29-35. 2001
    ..This study attempts to improve understanding of both patient and provider factors involved in lack of adherence to treatment in diabetic patients by using the conceptual model of attachment theory...
  12. ncbi The interaction of maternal and infant vulnerabilities on developing attachment relationships
    J Poehlmann
    Syracuse University, USA
    Dev Psychopathol 13:1-11. 2001
    ..Preterm infants with more symptomatic mothers were most likely to be classified as insecurely attached to their mothers, whereas no direct relation between subclinical depressive symptoms and attachment was found for full-term infants...
  13. ncbi Evidence of increased sensitivity using a three-factor version of the Parental Bonding Instrument
    Humberto Lizardi
    Department of Psychology, City University of New York at Lehman College, 250 Bedford Park Boulevard West, Bronx, New York 10468 1589, USA
    J Nerv Ment Dis 190:619-23. 2002
    ..The results indicated that the three-factor model revealed associations between parenting behaviors and different types of depression that were not evident using the two-factor structure's original dimensions...
  14. ncbi Emotional distress and prenatal attachment in pregnancy after perinatal loss
    Deborah Smith Armstrong
    University of Louisville School of Nursing, Louisville, KY, USA
    J Nurs Scholarsh 34:339-45. 2002
    ....
  15. ncbi Testing a family intervention hypothesis: the contribution of mother-infant skin-to-skin contact (kangaroo care) to family interaction, proximity, and touch
    Ruth Feldman
    Department of Psychology, Bar Ilan University, Ramat Gan, Israel 52900
    J Fam Psychol 17:94-107. 2003
    ..The role of touch as a constituent of the co-regulatory parent-infant and triadic systems and the effects of maternal contact on mothering, co-parenting, and family processes are discussed...
  16. ncbi Maternal-fetal attachment: an integrative review
    Barbara L Cannella
    College of Nursing, Rutgers University, 180 University Avenue, Newark, NJ 07102, USA
    J Adv Nurs 50:60-8. 2005
    ....
  17. doi Adult attachment and emotional processing biases: an event-related potentials (ERPs) study
    Orrie Dan
    Department of Psychology, The Center for Psychobiological Research, The Max Stern Academic College of Emek Yezreel, Israel
    Biol Psychol 91:212-20. 2012
    ..The present study underscores the usefulness of the ERP methodology, as a sensitive measure for the study of emotional processing biases in the research field of attachment...
  18. ncbi The impact of premature childbirth on parental bonding
    Hannah N Hoffenkamp
    International Victimology Institute Tilburg, Tilburg University, Tilburg, The Netherlands
    Evol Psychol 10:542-61. 2012
    ..These findings support the hypothesis that in affluent countries with adequate resources, bonding in parents of preterm infants on average may be higher than in parents of full-term infants...
  19. ncbi Using attachment theory to understand illness behavior
    J J Hunter
    University of Toronto Psychosomatic Program, Mount Sinai Hospital, 600 Uniuversity Ave, Toronto, Ontario, Canada M5G 1X5
    Gen Hosp Psychiatry 23:177-82. 2001
    ..Attachment theory provides a unique, simple, and pragmatically useful model for understanding the particular ways that individuals can feel and react when stressed by illness, and how the professional may help manage that distress...
  20. ncbi The reciprocal relationship between early adolescent attachment and internalizing and externalizing problem behaviour
    Kirsten L Buist
    Department of Educational Sciences, University of Amsterdam, PO Box 94208, Amsterdam 1090, The Netherlands
    J Adolesc 27:251-66. 2004
    ..Reciprocal negative effects were found between attachment and internalizing problem behaviour, and between attachment and externalizing problem behaviour...
  21. ncbi The Experiences in Close Relationship Scale (ECR)-short form: reliability, validity, and factor structure
    Meifen Wei
    Department of Psychology, Iowa State University, Ames 50011 3180, USA
    J Pers Assess 88:187-204. 2007
    ..Finally, the results were comparable when we embedded the short form within the original version of the ECR and when we administered it as a stand-alone measure...
  22. doi Adjusting to being a father to an infant born prematurely: experiences from Swedish fathers
    Birgitta Lindberg
    Division of Nursing, Department of Health Sciences, Lulea University of Technology, Lulea, Sweden
    Scand J Caring Sci 22:79-85. 2008
    ..The results of this study have implications for nurses working with families who have children born prematurely...
  23. pmc Infant bonding and attachment to the caregiver: insights from basic and clinical science
    Regina Sullivan
    The Emotional Brain Institute, The Nathan S Kline Institute for Psychiatric Research, Child and Adolescent Psychiatry, New York University School of Medicine, 215 Lexington Avenue, New York, NY 10016, USA
    Clin Perinatol 38:643-55. 2011
    ..Here we present attachment within an historical view and highlight the importance of integrating human and animal research in understanding infant care...
  24. ncbi Dating couples' attachment styles and patterns of cortisol reactivity and recovery in response to a relationship conflict
    Sally I Powers
    Department of Psychology, University of Massachusetts at Amherst, Amherst, MA, USA
    J Pers Soc Psychol 90:613-28. 2006
    ..The discussion emphasizes the role of gender role norms and partner characteristics in understanding connections between adult attachment and patterns of cortisol responses to interpersonal stress...
  25. ncbi Is social attachment an addictive disorder?
    Thomas R Insel
    Center for Behavioral Neuroscience, Emory University, Altanta, GA, USA
    Physiol Behav 79:351-7. 2003
    ..The neuropeptides oxytocin (OT) and vasopressin (AVP) appear to be critical for linking social signals to the mesocorticolimbic circuit...
  26. ncbi Contemporary research on parenting. The case for nature and nurture
    W A Collins
    National Institute of Child Health and Human Development, University of Minnesota 55455 0345, USA
    Am Psychol 55:218-32. 2000
    ..These approaches indicate that parental influences on child development are neither as unambiguous as earlier researchers suggested nor as insubstantial as current critics claim...
  27. ncbi Deficit in attachment behavior in mice lacking the mu-opioid receptor gene
    Anna Moles
    Consiglio Nazionale delle Ricerche Institute of Neuroscience, Psychobiology and Psychopharmacology, Viale Marx 43, 00137 Roma, Italy
    Science 304:1983-6. 2004
    ..Results from this study may indicate a molecular mechanism for diseases characterized by deficits in attachment behavior, such as autism or reactive attachment disorder...
  28. doi Early contact versus separation: effects on mother-infant interaction one year later
    Ksenia Bystrova
    Associate Professor, Department of Hospital Pediatrics, St Petersburg Pediatric Academy, St Petersburg, Russia
    Birth 36:97-109. 2009
    ..The aim of this study was to evaluate and compare possible long-term effects on mother-infant interaction of practices used in the delivery and maternity wards, including practices relating to mother-infant closeness versus separation...
  29. ncbi Attachment from infancy to early adulthood in a high-risk sample: continuity, discontinuity, and their correlates
    N S Weinfield
    Department of Psychology, University of Virginia, Charlottesville 22904, USA
    Child Dev 71:695-702. 2000
    ..These results provide evidence that although attachment has been found to be stable over time in other samples, attachment representations are vulnerable to difficult and chaotic life experiences...
  30. ncbi Attachment theory and intergroup bias: evidence that priming the secure base schema attenuates negative reactions to out-groups
    M Mikulincer
    Department of Psychology, Bar Ilan University, Ramat Gan, Israel
    J Pers Soc Psychol 81:97-115. 2001
    ..The discussion emphasizes the relevance of attachment theory for understanding intergroup attitudes...
  31. ncbi Match makers and deal breakers: analyses of assortative mating in newlywed couples
    David Watson
    Department of Psychology, E11 Seashore Hall, University of Iowa, Iowa City, IA, 52242 1407, USA
    J Pers 72:1029-68. 2004
    ..e., similarity at the time of marriage) rather than convergence (i.e., increasing similarity with time). Finally, marital satisfaction primarily was a function of the rater's own traits and showed little relation to spousal similarity...
  32. doi A novel examination of atypical major depressive disorder based on attachment theory
    Robert D Levitan
    Department of Psychiatry, University of Toronto, Mood and Anxiety Division, Centre for Addiction and Mental Health, c o CAMH, Toronto, Ontario, Canada
    J Clin Psychiatry 70:879-87. 2009
    ..As gender has been an important consideration in prior work on atypical depression, this same hypothesis was further tested in female subjects only...
  33. doi Adult attachment measures: a 25-year review
    Paula Ravitz
    Department of Psychiatry, University of Toronto, Toronto, Canada Mount Sinai Hospital and Joseph and Wolf Lebovic Health Complex, Toronto, Canada
    J Psychosom Res 69:419-32. 2010
    ..This article reviews the measurement of adult attachment, highlighting instruments of relevance to-or with potential use in-psychosomatic research...
  34. ncbi Parenting and development of one-year-olds: links with parental, contextual, and child characteristics
    Hedwig J A van Bakel
    Department of Developmental Psychology, University of Nijmegen, The Netherlands
    Child Dev 73:256-73. 2002
    ..Belsky's claim that parents' personal resources are most effective and child characteristics are least effective in buffering the parenting system was not empirically confirmed...
  35. ncbi The impact of maternal characteristics and contextual variables on infant-mother attachment
    Alissa C Huth-Bocks
    Department of Psychiatry, University of Michigan Health System, Ann Arbor, MI 48105, USA
    Child Dev 75:480-96. 2004
    ..The overall model indicated a good fit. Thus, both individual and contextual factors were important in explaining infant attachment security...
  36. ncbi A randomised controlled trial in the north of England examining the effects of skin-to-skin care on breast feeding
    Sue Carfoot
    Women s Health Directorate, North Cheshire Hospitals NHS Trust, Warrington, UK
    Midwifery 21:71-9. 2005
    ..to examine the effect of early skin-to-skin contact between mothers and their healthy full-term babies on initiation and duration of breast feeding...
  37. ncbi Some thoughts on the neurobiology of stalking
    J Reid Meloy
    Department of Psychiatry, Univ of California, San Diego, PO Box 90699, San Diego, CA 92169, USA
    J Forensic Sci 50:1472-80. 2005
    ..They conclude that stalking may be associated with a specific set of biological components and they offer suggestions for further research into this pathological emotional/motivational state...
  38. ncbi Neural representation of maternal face processing: a functional magnetic resonance imaging study
    Rajamannar Ramasubbu
    Department of Psychiatry and Clinical Neurosciences, Hotchkiss Brain Institute, Univesity of Calgary, Calgary, Alberta
    Can J Psychiatry 52:726-34. 2007
    ..The mother-child relationship may have important implications for emotional development and adult psychopathology. The objective of this study was to examine brain responses to processing maternal faces in healthy adult women...
  39. doi Coregulation, dysregulation, self-regulation: an integrative analysis and empirical agenda for understanding adult attachment, separation, loss, and recovery
    David A Sbarra
    Department of Psychology, University of Arizona, Tucson, AZ 85721 0068, USA
    Pers Soc Psychol Rev 12:141-67. 2008
    ..Research evidence is reviewed across multiple levels of analysis, and the article concludes with a series of testable research questions on the interconnected nature of attachment, loss, and recovery processes...
  40. doi On the rebound: focusing on someone new helps anxiously attached individuals let go of ex-partners
    Stephanie S Spielmann
    Department of Psychology, University of Toronto, Toronto, Ontario, M5S 3G3, Canada
    Pers Soc Psychol Bull 35:1382-94. 2009
    ..This research suggests that for anxiously attached individuals, focusing on someone new can be an adaptive part of the breakup recovery process...
  41. doi Enhancing attachment security in the infants of women in a jail-diversion program
    Jude Cassidy
    University of Maryland, USA
    Attach Hum Dev 12:333-53. 2010
    ..Given the lack of a randomized control group, results are discussed in terms of the exploratory, program-development nature of the study...
  42. pmc Attachment organization in a sample of incarcerated mothers: distribution of classifications and associations with substance abuse history, depressive symptoms, perceptions of parenting competency and social support
    Jessica L Borelli
    Department of Psychology, Pomona College, Claremont, USA
    Attach Hum Dev 12:355-74. 2010
    ..Higher scores on unresolved loss and derogation were associated with a history of substance abuse; higher scores on unresolved trauma were associated with depressive symptoms at program completion...
  43. doi Parental incarceration: the challenges for attachment researchers
    Inge Bretherton
    Department of Human Development and Family Studies, University of Wisconsin Madison, Madison, WI 53706, USA
    Attach Hum Dev 12:417-28. 2010
    ....
  44. pmc Variation in the μ-opioid receptor gene (OPRM1) moderates the influence of early maternal care on fearful attachment
    Alfonso Troisi
    Department of Neurosciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Soc Cogn Affect Neurosci 7:542-7. 2012
    ....
  45. doi Parental overprotection increases sociotropy with gender specificity in parents and recipients
    Koichi Otani
    Department of Psychiatry, Yamagata University School of Medicine, Japan
    J Affect Disord 136:824-7. 2012
    ..The purpose of the present study was to examine the effects of parental rearing on sociotropy and autonomy, the personality vulnerability factors in the cognitive theory of depression...
  46. ncbi Stability and change in mothers' internal representations of their infants over time
    Sally A Theran
    Psychology Department, Wellesley College, 480 Science Center, Wellesley, MA 02481, USA
    Attach Hum Dev 7:253-68. 2005
    ..In addition, women who became non-balanced postnatally benefited from having balanced representations while pregnant to buffer the quality of their interactions with their children...
  47. ncbi Development and evolution of hidden regulators: selective breeding for an infantile phenotype
    Susan A Brunelli
    Department of Developmental Psychobiology, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York 10032, USA
    Dev Psychobiol 47:243-52. 2005
    ..As animal models, the lines have the potential to provide valuable tools for understanding developmental mechanisms underlying genetic and developmental risk for depression/anxiety syndromes in children and adults...
  48. ncbi Outcomes of Prolonged Parent-Child Embrace Therapy among 102 children with behavioral disorders
    Martha G Welch
    The Martha G Welch Center, New York, NY, USA
    Complement Ther Clin Pract 12:3-12. 2006
    ..001). Results showed that PPCE Therapy resulted in significant and prolonged improvements in symptomatic behavior in a majority of children...
  49. doi Attachment-past and present. But what about the future?
    Heidi Keller
    Department of Culture and Development, University of Osnabruck, Artilleriestrasse 34, 49076, Osnabruck, Germany
    Integr Psychol Behav Sci 42:406-15. 2008
    ....
  50. ncbi Insecure and disorganised attachment in children with a pervasive developmental disorder: relationship with social interaction and heart rate
    S H Willemsen-Swinkels
    Department of Child and Adolescent Psychiatry, Utrecht University, The Netherlands
    J Child Psychol Psychiatry 41:759-67. 2000
    ....
  51. ncbi Attachment in mental health institutions: a critical review of assumptions, clinical implications, and research strategies
    C Schuengel
    Department of Orthopedagogy, Faculty of Psychology and Pedagogy, Amsterdam, The Netherlands
    Attach Hum Dev 3:304-23. 2001
    ....
  52. ncbi Holism, contextual variability, and the study of friendships in adolescent development
    Robert Crosnoe
    Department of Sociology and Population Research Center, University of Texas at Austin, 78712 1088, USA
    Child Dev 75:264-79. 2004
    ....
  53. doi Perceived attachment: relations to anxiety sensitivity, worry, and GAD symptoms
    Andres G Viana
    Department of Psychology, The Pennsylvania State University, University Park, PA 16802, USA
    Behav Res Ther 46:737-47. 2008
    ..The facets fear of publicly observable symptoms and fear of cognitive dyscontrol also mediated this relation. The role of alienation in relation to AS, worry, and GAD symptoms is discussed along with directions for future research...
  54. doi Attachment and God representations among lay Catholics, priests, and religious: a matched comparison study based on the Adult Attachment Interview
    Rosalinda Cassibba
    Department of Psychology, University of Bari, Bari, Italy
    Dev Psychol 44:1753-63. 2008
    ..These results extend the literature on religion from an attachment perspective and support the idea that generalized working models derived from attachment experiences with parents are reflected in believers' perceptions of God...
  55. pmc Maternal resolution of grief after preterm birth: implications for infant attachment security
    Prachi E Shah
    Division of Child Behavioral Health, Department of Pediatrics, Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, USA
    Pediatrics 127:284-92. 2011
    ..We hypothesized that mothers with unresolved grief would be more likely to have insecurely attached infants at 16 months and that this association would be partially mediated by maternal interaction quality...
  56. ncbi Genetic and environmental influences on a measure of infant attachment security
    D Finkel
    Indiana University Southeast, New Albany 47150, USA
    Twin Res 3:242-50. 2000
    ..No evidence was found for a contribution from shared environmental influences to attachment security. Possible concerns about the validity of twin methodology are addressed and various interpretations of the results are presented...
  57. ncbi Relation of attachment style to family history of alcoholism and alcohol use disorders in early adulthood
    Martha Vungkhanching
    University of Missouri Columbia, and the Midwest Alcoholism Research Center, 200 South 7th Street, Columbia, MO 65201, USA
    Drug Alcohol Depend 75:47-53. 2004
    ..Our findings suggest that insecure attachment style is a risk factor for AUD, independent of familial risk for alcoholism...
  58. ncbi Back to basics: attachment, affect regulation, and the developing right brain: linking developmental neuroscience to pediatrics
    Allan N Schore
    Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, David Geffen School of Medicine, Los Angeles, California, USA
    Pediatr Rev 26:204-17. 2005
  59. ncbi Caregiver--child interaction in infants and toddlers born extremely premature
    Bonnie Keilty
    Depaprtment of Curriculum and Teacing, Teachers College, Columbia University, New York, NY 10027, USA
    J Pediatr Nurs 20:181-9. 2005
    ..Caregiver interaction was related to later child interaction but not developmental status. Implications for intervention and developmental surveillance are discussed...
  60. ncbi What can make the difference? Premature birth and maternal sensitivity at 3 months of age: the role of attachment organization, traumatic reaction and baby's medical risk
    Gabrielle Coppola
    Department of Biomedical Sciences, University G d Annunzio of Chieti, Italy
    Infant Behav Dev 30:679-84. 2007
    ..Results show a main effect of attachment and an interaction between attachment and prematurity. Sensitivity was differently associated with medical risk and mothers' traumatic reaction, depending on the quality of attachment...
  61. doi Comparison of maternal-and paternal-fetal attachment in Turkish couples
    A Ustunsoz
    Gulhane Military Medical Academy, School of Nursing, Ankara, Turkey
    Midwifery 26:e1-9. 2010
    ..to compare maternal-fetal attachment (MFA) and paternal-fetal attachment (PFA) in terms of selected variables...
  62. ncbi Attachment to groups: theory and measurement
    E R Smith
    Department of Psychological Sciences, Purdue University, West Lafayette, Indiana 47907 1364, USA
    J Pers Soc Psychol 77:94-110. 1999
    ..This conceptualization provides new insights into the nature of people's psychological ties to groups...
  63. ncbi Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganization in infants
    K Lakatos
    Social Development Group, Institute of Psychology, Hungarian Academy of Sciences, Budapest
    Mol Psychiatry 5:633-7. 2000
    ..15. We suggest that, in non-clinical, low-social-risk populations, having a 7-repeat allele predisposes infants to attachment disorganization...
  64. ncbi Addiction as an attachment disorder: implications for group therapy
    P J Flores
    Georgia School of Professional Psychology, Atlanta, GA, USA
    Int J Group Psychother 51:63-81. 2001
    ..Prolonged stress on existing structures leads to exaggerated difficulty in the regulation of affect, which leads to inadequate modulation of appropriate behavior and self-care and increased character pathology...
  65. ncbi Peer relations in the transition to adolescence
    Carollee Howes
    Department of Education, University of California at Los Angeles, Los Angeles, California 90095, USA
    Adv Child Dev Behav 29:195-230. 2002
  66. ncbi Adolescents' attachment representations and developmental tasks in emerging adulthood
    Miri Scharf
    Faculty of Education, University of Haifa, Haifa, Israel
    Dev Psychol 40:430-44. 2004
    ..The results highlight the importance of attachment representations in shaping an individual's developmental trajectory...
  67. ncbi Is prenatal bonding enhanced by prenatal education courses?
    C V Bellieni
    Department of Pediatrics, Obstetrics and Reproduction Medicine, University of Siena, Policlinico Le Scotte, Viale M Bracci, 53100 Siena, Italy
    Minerva Ginecol 59:125-9. 2007
    ..Here we investigated whether they can enhance feto-maternal bonding...
  68. ncbi Parental attachment, premorbid personality, and mental health in young males with hyperventilation syndrome
    Bih Ching Shu
    Institute of Allied Health Sciences and School of Nursing, National Cheng Kung University, Tainan, Taiwan
    Psychiatry Res 153:163-70. 2007
    ..The determination of competing risk factors and mediating effects in males with hyperventilation syndrome should be considered in future studies...
  69. pmc Mu-opioid receptor (OPRM1) variation, oxytocin levels and maternal attachment in free-ranging rhesus macaques Macaca mulatta
    James P Higham
    Institute for Mind and Biology, The University of Chicago, 940 East 57th Street, Chicago, IL 60637, USA
    Behav Neurosci 125:131-6. 2011
    ....
  70. ncbi Adult attachment style and individual differences in functional versus dysfunctional experiences of anger
    M Mikulincer
    Department of Psychology, Bar Ilan University, Ramat Gan, Israel
    J Pers Soc Psychol 74:513-24. 1998
    ..For avoidant persons, it included high hostility, escapist responses, and lack of awareness of physiological signs of anger. The underlying action of working models is emphasized in the discussion...
  71. ncbi Attachment style and symptom reporting: examining the mediating effects of anger and social support
    Tara Kidd
    Staffordshire University, UK
    Br J Health Psychol 10:531-41. 2005
    ..Attachment style has been related to symptom reporting. The aim of this research was to examine whether social support and anger expression or experience mediate this relationship...
  72. ncbi The relationship of attachment insecurity to subjective stress and autonomic function during standardized acute stress in healthy adults
    Robert G Maunder
    Department of Psychiatry, Mount Sinai Hospital, University of Toronto, Toronto, Canada
    J Psychosom Res 60:283-90. 2006
    ..The purpose of this study was to test predicted relationships between adult attachment and stress using subjective and physiological measures...
  73. doi Attachment status and salivary cortisol in a normal day and during simulated interpersonal stress in young men
    Anne Rifkin-Graboi
    University of California, Berkeley, USA
    Stress 11:210-24. 2008
    ..However, in keeping with expectations, associations between insecurity, and in particular dismissing idealization, and comparatively higher cortisol values following interpersonal challenges were observed...
  74. doi The influence of attachment on perceived stress and cortisol response to acute stress in women sexually abused in childhood or adolescence
    Blaise Pierrehumbert
    Lausanne University, Department of Child and Adolescent Psychiatry, SUPEA, 25a rue du Bugnon, CH 1011 Lausanne, Switzerland
    Psychoneuroendocrinology 34:924-38. 2009
    ....
  75. doi Assessing patterns of adult attachment in medical patients
    Robert G Maunder
    Department of Psychiatry, Mount Sinai Hospital, Toronto, Ontario, Canada
    Gen Hosp Psychiatry 31:123-30. 2009
    ..Patterns of adult attachment affect physical health and yet are unfamiliar to many clinicians. The purpose of this review was to derive descriptions of prototypic patterns of adult attachment that are relevant to health care...
  76. ncbi Family issues in child anxiety: attachment, family functioning, parental rearing and beliefs
    Susan M Bögels
    University of Amsterdam, Faculty of Social and Behavioral Sciences, Department of Education, PO Box 94208, 1090 GE Amsterdam, The Netherlands
    Clin Psychol Rev 26:834-56. 2006
    ..Finally, parental beliefs are identified as important predictors of parental behaviour that have largely not been investigated in relation to child anxiety disorders...
  77. ncbi The relationship between joint attention and pretend play in autism
    T Charman
    Sub Department of Clinical Health Psychology, University College London, UK
    Dev Psychopathol 9:1-16. 1997
    ..It also suggests directions for future work to clarify the relationship between the two skills and to identify the nature of the underlying primary deficit in autism...
  78. ncbi Adult attachment in a nationally representative sample
    K D Mickelson
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Pers Soc Psychol 73:1092-106. 1997
    ..Various types of adult psychopathologies and personality traits were also strongly related to adult attachment. Implications for adult attachment theory and future research are discussed...
  79. ncbi Attachment security in infancy and early adulthood: a twenty-year longitudinal study
    E Waters
    Department of Psychology, State University of New York at Stony Brook, 11794 2500, USA
    Child Dev 71:684-9. 2000
    ..The task now is to use a variety of research designs, measurement strategies, and study intervals to clarify the mechanisms underlying stability and change...
  80. ncbi Attachment security: a meta-analysis of maternal mental health correlates
    L Atkinson
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Clin Psychol Rev 20:1019-40. 2000
    ....
  81. ncbi Attachment stability and emotional and behavioral regulation from infancy to preschool age
    J I Vondra
    Department of Psychology in Education, University of Pittsburgh, PA 15260-7478, USA
    Dev Psychopathol 13:13-33. 2001
    ..Results are discussed in terms of continuity and change from the perspective of developmental psychopathology...
  82. ncbi Infant-mother attachment security, contextual risk, and early development: a moderational analysis
    Jay Belsky
    Institute for the Study of Children, Families and Social Issues, Birkbeck University of London, UK
    Dev Psychopathol 14:293-310. 2002
    ..Findings are discussed in terms of risk and resilience and in light of the probabilistic nature of the relation between early attachment and later development...
  83. ncbi Attachment theory: a model for health care utilization and somatization
    Paul S Ciechanowski
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA
    Psychosom Med 64:660-7. 2002
    ....
  84. ncbi Autism and attachment: a meta-analytic review
    Anna H Rutgers
    Center for Child and Family Studies, Leiden University, The Netherlands
    J Child Psychol Psychiatry 45:1123-34. 2004
    ..Sixteen studies on attachment in children with autism were reviewed, and ten studies with data on observed attachment security (N = 287) were included in a quantitative meta-analysis...
  85. ncbi Influence of various early human-foal interferences on subsequent human-foal relationship
    S Henry
    UMR CNRS 6552, Ethologie Evolution Ecologie, Universite de Rennes 1, Avenue du General Leclerc, Campus de Beaulieu, F 35042 Rennes Cedex, France
    Dev Psychobiol 48:712-8. 2006
    ..This way of investigation may have important general implications in how we consider the development of social relations, both within and between species...
  86. ncbi Parental sensitivity and attachment in children with autism spectrum disorder: comparison with children with mental retardation, with language delays, and with typical development
    Marinus H van IJzendoorn
    Centre for Child and Family Studies, Radboud University Nijmegen Medical Center, The Netherlands
    Child Dev 78:597-608. 2007
    ..More sensitive parents had more secure children, but only in the group without ASD. Less severe autistic symptoms in the social domain predicted more attachment security. Autism challenges the validity of attachment theory...
  87. ncbi Are 6-month-old foals sensitive to dam's influence?
    S Henry
    UMR CNRS 6552 Ethologie Evolution Ecologie, Universite de Rennes 1, Avenue du General Leclerc, Campus de Beaulieu, F 35042 Rennes Cedex, France
    Dev Psychobiol 49:514-21. 2007
    ..We observe a positive effect of mare' handling on foals' reactions to humans but with a high interindividual variability, suggesting a higher effect of the foals' own behavioral characteristics at this age than at earlier stages...
  88. ncbi Friendship in high-functioning children with autism spectrum disorder: mixed and non-mixed dyads
    Nirit Bauminger
    School of Education, Bar Ilan University, Ramat Gan 52900, Israel
    J Autism Dev Disord 38:1211-29. 2008
    ..Exposure to typical peers appears to have significant effects on friendship behaviors...
  89. doi Mothers of securely attached children with autism spectrum disorder are more sensitive than mothers of insecurely attached children
    Nina Koren-Karie
    Center for the Study of Child Development, University of Haifa, Haifa, Israel
    J Child Psychol Psychiatry 50:643-50. 2009
    ..low), and children's levels of responsiveness. The significance of sensitivity for security of attachment in ASD and the implications of these findings for the validity of the SSP in children with ASD are discussed...
  90. doi Living together apart: perceived concealment as a signal of exclusion in marital relationships
    Catrin Finkenauer
    Department of Social Psychology, Vrije Universiteit, Amsterdam Netherlands
    Pers Soc Psychol Bull 35:1410-22. 2009
    ..This article demonstrates that the perception of concealment (a) has deleterious effects on relational well-being in the long run and (b) is harmful in part because it elicits feelings of exclusion...
  91. ncbi Attachment styles, emotion regulation, and adjustment in adolescence
    M L Cooper
    Department of Psychology, University of Missouri Columbia 65211, USA
    J Pers Soc Psychol 74:1380-97. 1998
    ..Finally, patterns of attachment effects were similar across age, gender, and racial groups, with some important exceptions...
  92. ncbi Mothering, fathering, and infant negativity as antecedents of boys' externalizing problems and inhibition at age 3 years: differential susceptibility to rearing experience?
    J Belsky
    Pennsylvania State University, University Park 16802, USA
    Dev Psychopathol 10:301-19. 1998
    ....
  93. ncbi The development of anxiety: the role of control in the early environment
    B F Chorpita
    Department of Psychology, University of Hawaii, Manoa, USA
    Psychol Bull 124:3-21. 1998
    ..Implications for research are discussed...
  94. ncbi Attachment styles and personality disorders: their connections to each other and to parental divorce, parental death, and perceptions of parental caregiving
    K A Brennan
    Department of Psychology, State University of New York, Brockport 14420 2914, USA
    J Pers 66:835-78. 1998
    ..Results are discussed in terms of encouraging further research to test the idea that insecure attachment and most of the personality disorders share similar developmental antecedents...
  95. ncbi Neuroendocrine perspectives on social attachment and love
    C S Carter
    Department of Biology, University of Maryland, College Park 20742, USA
    Psychoneuroendocrinology 23:779-818. 1998
    ..Social interactions and attachment involve endocrine systems capable of decreasing HPA reactivity and modulating the autonomic nervous system, perhaps accounting for health benefits that are attributed to loving relationships...
  96. ncbi An item response theory analysis of self-report measures of adult attachment
    R C Fraley
    Department of Psychology, University of California, Davis 95616 8686, USA
    J Pers Soc Psychol 78:350-65. 2000
    ..Accordingly, the authors show how IRT techniques can be used to develop new attachment scales with desirable psychometric properties...
  97. ncbi A safe haven: an attachment theory perspective on support seeking and caregiving in intimate relationships
    N L Collins
    Department of Psychology, State University of New York at Buffalo, USA
    J Pers Soc Psychol 78:1053-73. 2000
    ..Finally, couples in better functioning relationships engaged in more supportive interactions, and participants' perceptions of their interaction were biased by relationship quality and attachment style...
  98. ncbi Continuity and discontinuity of attachment from infancy through adolescence
    C E Hamilton
    Elementary Education, University of Georgia, Athens 30602, USA
    Child Dev 71:690-4. 2000
    ....
  99. ncbi Child-parent attachment and children's peer relations: a quantitative review
    B H Schneider
    School of Psychology, University of Ottawa, Ontario, Canada
    Dev Psychol 37:86-100. 2001
    ..Gender and cultural differences in ESs were minimal. The results for the few studies on father-child attachment were inconclusive...
  100. ncbi The neurobiology of attachment
    T R Insel
    Center for Behavioral Neuroscience, 954 Gatewood Road Northeast, Emory University, Atlanta, Georgia 30329, USA
    Nat Rev Neurosci 2:129-36. 2001
    ..This review describes some of the important insights from this work...
  101. ncbi Structure and variability in the developmental trajectory of children's externalizing problems: impact of infant attachment, maternal depressive symptomatology, and child sex
    J A Munson
    Center on Human Development and Disability, University of Washington, Seattle 98195 7920, USA
    Dev Psychopathol 13:277-96. 2001
    ....

Research Grants74

  1. Infant Screening and Diagnosis of Duchenne Muscular Dys*
    Paul Fernhoff; Fiscal Year: 2007
    ..These data points will be tracked throughout the project. ..
  2. KINETICS OF DRUG MACROMOLECULE COMPLEX FORMATION
    PALMER WILLIAM TAYLOR; Fiscal Year: 2013
    ....
  3. Jay R Winkler; Fiscal Year: 2016
    ..Efforts will focus on oxidative generation of Compounds I and II in cytochromes P450 (Aim 3) and a bacterial enzyme that exhibits NOS-like reactivity (Aim 4). ..
  4. Yi Lu; Fiscal Year: 2016
    ..Therefore the work will make important contributions to healthcare, as it will provide a molecular basis for understanding two enzymes important to human health. ..
  5. SIMULATION OF PROTON AND HYDRIDE TRANSFER IN ENZYMES
    Sharon Hammes Schiffer; Fiscal Year: 2010
    ....
  6. Computational Design of Small Molecule Drugs Inhibiting the Zinc Finger Transcrip
    David Sherris; Fiscal Year: 2010
    ..Work from this project will further advance our knowledge on zinc finger protein transcription factor/DNA interactions and may thus open the door to a whole new range of therapeutic agents. ..
  7. BLOOD PRESSURE REGULATION, STRESS AND MATERNAL OXYTOCIN RESPONSE
    Kathleen C Light; Fiscal Year: 2010
    ....
  8. RNA Modification Enzymes: Methyltransferase/psi-synthase
    Robert M Stroud; Fiscal Year: 2012
    ..The importance of synthase activity is underlined by disorders such as sideroplastic anemia. The RNA MTase is a potential new drug target for anti-HIV therapy. ..
  9. Shaojie Zhang; Fiscal Year: 2014
    ..We expect that the proposed work will lead to better understanding of the RNA structural motifs, and significantly promote biomedical research. ..
  10. Roger L Papke; Fiscal Year: 2016
    ..We will use our new discoveries about how these drugs work to help make alpha7-stimulating drugs optimally designed to treat specific diseases. ..
  11. Implementation of Microfluidic Automation for Large-Scale Searches of Olfactory N
    Albert Folch; Fiscal Year: 2012
    ..g. PCR amplification) after characterizing their response to known compounds. ..
  12. Young Development of a Novel PET Ligand for Detecting Oxytocin Receptors in Brain
    Larry J Young; Fiscal Year: 2012
    ....
  13. Control of AMPA receptor function by phosphorylation
    Stephen F Traynelis; Fiscal Year: 2013
    ....
  14. Hartmut Luecke; Fiscal Year: 2016
    ..pylori and to affect survival in a novel gastro-mimetic incubation system. ..
  15. Coregulatory Processes and Postpartum Depression in Mexican-Americans
    Linda J Luecken; Fiscal Year: 2013
    ....
  16. Cancer prevention, mental health and social capital of segregated Black Americans
    LORRAINE TIERA DEAN; Fiscal Year: 2010
    ..Data will be aggregated and geocoded to segregated areas of Philadelphia County using a novel measure of segregation based on 2000 US Census Data. ..
  17. 2012 Iron Sulfur Enzymes Gordon Research Conference
    Markus W Ribbe; Fiscal Year: 2012
    ....
  18. JoAnne Stubbe; Fiscal Year: 2016
    ..The aim of this proposal is to study RNR's unique mechanism, the understanding of which will aid in developing novel RNR inhibitors. ..
  19. Jan Ching Chun Hu; Fiscal Year: 2016
    ..Future genetic analyses may link genetic changes in these genes to susceptibility for dental caries and provide insights into mechanisms of tooth formation. ..
  20. Characterization of the Transcriptome in an Emerging Model for Social Behavior
    James W Thomas; Fiscal Year: 2010
    ....
  21. Marcy A Kingsbury; Fiscal Year: 2015
    ..Such processes are poorly understood, but are of clear relevance to mental health. ..
  22. Larry J Young; Fiscal Year: 2016
    ..This work will inform future development of novel therapeutic strategies to enhance social function in ASD and other psychiatric disorders. ..
  23. Vasopressin in the regulation of serotonin and anxiety
    BENJAMIN DAVID ROOD; Fiscal Year: 2013
    ..abstract_text> ..
  24. HORMONE-NEUROTRANSMITTER INTERACTIONS IN THE BRAIN
    Elaine M Hull; Fiscal Year: 2011
    ....
  25. X-RAY AND CHEMICAL STUDIES OF METALLOPORPHYRINS
    W Robert Scheidt; Fiscal Year: 2010
    ..The effect of pressure will be investigated through the measurement of the NRVS spectrum at pressures up to about 8 GPa. Whenever possible, these measurements will be made on an oriented crystal specimen. ..
  26. The North Carolina Cleft Outcomes Study
    Ronald P Strauss; Fiscal Year: 2013
    ..Results will improve understanding of short and long-term outcomes among children with OFC. This can enhance health and quality of life for children with these conditions and their families. ..
  27. Self-assembling Biomimetic Hydrogels with Bioadhesive Properties for Intervertebr
    ANDREA JENNIFER VERNENGO; Fiscal Year: 2013
    ....
  28. Ethanol-induced conditioned partner preference in mice
    Ruth I Wood; Fiscal Year: 2013
    ..Aim 3 will test the ability of a V1a receptor antagonist to block EtOH-induced conditioned partner preference. Together, these studies represent an essential first-step to understand substance abuse and social bonding in mice. ..
  29. ENAMEL MINERAL FORMATION DURING MURINE ODONTOGENESIS
    CAROLYN GIBSON; Fiscal Year: 2012
    ..Mouse models mimic the human defects and can be used to correlate individual gene mutations with appropriate clinical intervention. ..
  30. The Molecular Basis of Alcohol's Actions
    DAVID NIGEL JONES; Fiscal Year: 2010
    ..This may allow future development of novel approaches to prevent alcohols actions, and the identification of genetic markers associated with a predisposition to alcoholism. ..
  31. Maureen G Phipps; Fiscal Year: 2016
    ....
  32. Computational Modeling of Post-translational Modifications in Proteins
    CHAYA K RAPP; Fiscal Year: 2011
    ....
  33. Floyd E Romesberg; Fiscal Year: 2015
    ..Completion of the proposed work will also position us at the doorstep of creating the first semi-synthetic organism, able to store, retrieve, and evolve, with more information than natural organisms. ..
  34. Kenneth D Karlin; Fiscal Year: 2016
    ..In-hand heme/Cu assemblies enable this chemistry and further mechanistic probing is necessary;these processes are critical to NO signaling and linked to cellular responses to changes in [O2] concentrations. ..
  35. MODEL SYNTHETIC CHANNEL ASSEMBLIES
    John M Tomich; Fiscal Year: 2013
    ..Other replacements will alterpore length and rigidity. The effects of these modifications will be monitored by a combination of electrophysiological and structural (CD &NMR) studies in conjunction with computer modeling. ..
  36. Ellen A Lumpkin; Fiscal Year: 2016
    ..By identifying mechanisms that govern the reliability of touch-evoked signals in healthy skin, these studies will set the stage to determine how these mechanisms fail in aging and pathophysiological states. ..
  37. Chondrogenic composite grafts for the repair of cartilage defects
    Jie Song; Fiscal Year: 2010
    ..The successful development of viable synthetic cartilage constructs has significant social and economic implications, and contributes to improving the musculoskeletal health of the general population. ..
  38. ULTRAFAST PROCESSES IN PROTEINS AND OTHER ASSEMBLIES
    Feng Gai; Fiscal Year: 2013
    ..A molecular level knowledge of enzyme-inhibitors for HIV treatments and amyloid fibrils associated with Alzheimer's disease form another focus of this work. ..
  39. Oxytocin regulation of social buffering following stress
    ADAM STEVEN SMITH; Fiscal Year: 2012
    ..This research program represents several steps in examining the neurobiology mechanism underlying the social buffering effect in prairie voles. ..
  40. Louis Noodleman; Fiscal Year: 2016
    ..Understanding the structures, mechanisms, and functions of mitochondrial CcO's is important for better analysis of many genetic and metabolic diseases and cancers, and is also relevant to pathologies of aging. ..
  41. Sharon Hammes-Schiffer; Fiscal Year: 2016
    ..Furthermore, insights into RNA catalysis may assist in the development of ribozymes for use as therapeutic agents to cleave pathogenic RNAs. ..
  42. Cocaine disruption of maternal motivation: preference for pups vs. cocaine
    MARIANA PEREIRA ARBOLEYA; Fiscal Year: 2010
    ..This preclinical information might contribute to the development of strategies for treatments or methods of prevention of this tragic human condition, with particular emphasis in maintaining or restoring mother- infant bonding. ..
  43. Colloidal Quantum Dot/Well Near-Infrared NanoLabels
    Hua Mao; Fiscal Year: 2010
    ..The commercialization of the proposed technologies will improve the health conditions of Americans, save lives, and help to maintain a sustainable environment. ..
  44. Efficacy of an Exercise Intervention for the Prevention of PostPartum Depression
    Beth A Lewis; Fiscal Year: 2010
    ..If efficacious, our intervention could be disseminated in "real world settings" in an effort to prevent postpartum depression. ..
  45. Light Scattering & Flourescence Study of Sugar Solutions as Cryoprotective Agents
    DAVID LEE SIDEBOTTOM; Fiscal Year: 2010
    ..e., degree of vitrification), (2) a function of gelation or (3) a function of water replacement caused by sugar bonding. ..
  46. Cecilia Tommos; Fiscal Year: 2016
    ..To increase our knowledge in this research area, we have developed a library of well- structured model proteins specifically made to study the chemical properties of protein radicals. ..
  47. Novel Antibacterial Fluoride-releasing Dental Materials
    Xiaoming Xu; Fiscal Year: 2012
    ..3) The combined use of an antibacterial fluoride-releasing composite, bonding agent and bioactive sealant will further reduce caries. ..
  48. Wireless Cardiorespiratory Monitor for Neonates
    MICHAEL JOHN SCIARRA; Fiscal Year: 2012
    ..The ease of application and lack of wires will increase compliance with in home monitoring protocols as well as allow for better bonding of parents in and out of hospital settings. ..
  49. Exploring tyrosine redox chemistry in model proteins
    MELISSA MARTINEZ-RIVERA; Fiscal Year: 2013
    ..For this reason, we have developed a series of model protein scaffolds with the characteristics necesary to investigate the relation between the thermodynamics of amino-acid redox chemistry and the surrounding protein environment. ..
  50. Reasons for poor durability of resin-dentin bonds
    David H Pashley; Fiscal Year: 2013
    ..Their successful use in adhesive resins could potentially save billions of dollars currently spent on the replacement of tooth-colored resin composites. ..
  51. Self Assembly of Cartilage by Mesenchymal Stem Cells on Porous Chitosan/CaP
    STEVEN HOWARD ELDER; Fiscal Year: 2010
    ..This project develops a joint resurfacing strategy based on a biphasic construct of self-assembled cartilage attached to a porous calcium phosphate-chitosan composite scaffold. ..
  52. Synaptic Transmission In Mammalian Cutaneous Touch Receptors
    Srdjan Maksimovic; Fiscal Year: 2013
    ..This allows me to test if selective excitation of Merkel cells with light evokes action potentials in SAI afferents. ..
  53. STRUCTURE AND REGULATION OF HUMAN FACTOR VIII
    Philip J Fay; Fiscal Year: 2013
    ....
  54. MARGARET M MORAN-SANTA MARIA; Fiscal Year: 2014
    ..Comparisons between men and women with a history of child abuse with and without PTSD will provide critical information regarding sex differences in the neural substrates of resilience. ..
  55. Steven H Graham; Fiscal Year: 2016
    ..The current project aims to identify a downstream mechanism by which COX2 activity injures neurons which could lead to new treatments for stroke and neurodegenerative diseases. ..
  56. Maternal behavior and effects of paternal affiliation in 5-HT1a overexpressing mi
    Juan F Lopez; Fiscal Year: 2010
    ..It is hoped that this animal model will be a useful tool in understanding the specific gene-environment interactions that modulate the expression of maternal care. ..
  57. PURIFICATION OF EPIDERMOLYSIS BULLOSA ANTIGEN
    David T Woodley; Fiscal Year: 2012
    ..The proposed studies will facilitate developing effective therapy for devastating skin diseases and chronic non-healing wounds. ..
  58. STRUCTURE AND FUNCTION OF NUCLEIC ACID THERAPEUTICS
    Martin Egli; Fiscal Year: 2012
    ..Other approaches we will rely on to achieve our objectives are synthetic organic chemistry, biochemical and molecular biology tools as well as thermodynamics, kinetics and single-crystal NMC. ..
  59. Gregory A Voth; Fiscal Year: 2016
    ..These studies will be carried out in collaboration with a number of leading experimentalists, while adding a new dimension to the field of biomolecular computer simulation as a whole. 1 ..
  60. Structural bioinformatics software for epitope selection and antibody engineering
    STEVEN JOSEPH DARNELL; Fiscal Year: 2012
    ..This will accelerate the discovery of new monoclonal antibody pharmaceuticals, leading to improved human health across many diseases. ..
  61. Systems of Care for New Moms: Integrating Depression Treatment
    Luis H Zayas; Fiscal Year: 2010
    ..The postpartum period is a window of opportunity in which to address depression in women because they are more likely to come into contact with the health care system. ..
  62. NALTREXONE PRODRUGS FOR TRANSDERMAL DELIVERY
    Audra L Stinchcomb; Fiscal Year: 2010
    ....
  63. REACTION MECHANISM OF MYOCARDIAC UBIQUINONE-PROTEINS
    Chang An Yu; Fiscal Year: 2009
    ..For type specifications, see instructions on page 6.) RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description, ..
  64. ELECTROSTATIC SURFACE OPTIMIZATION FOR OSSEOINTEGRATION
    Michele Marcolongo; Fiscal Year: 2000
    ..Further, we hypothesize that the quantity of fibronectin adsorbed to differently charged surfaces will not differ, but the conformation of the fibronectin on those charged surfaces will. ..
  65. Neonatal Phototherapy / Bilirubin Excretion
    DAVID LIGHTNER; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  66. MOLECULAR RECOGNITION IN THE STREPTAVIDIN BIOTIN SYSTEM
    Patrick Stayton; Fiscal Year: 2002
    ..The streptavidin mutants could also be useful reagents in affinity separations, diagnostics, and targeted drug discovery. ..
  67. MOLECULAR RECOGNITION IN THE STREPTAVIDIN BIOTIN SYSTEM
    Patrick Stayton; Fiscal Year: 2001
    ..The streptavidin mutants could also be useful reagents in affinity separations, diagnostics, and targeted drug discovery. ..
  68. POLYMER-COATED RED BLOOD CELL FOR SICKLE CELL DISEASE
    TIMOTHY FISHER; Fiscal Year: 2003
    ..g., alloimmunized rabbit model, xenotransfusions) methods. An interactive approach to these aims is proposed; their successful achievement should yield important new data and improved health care in SCD. ..
  69. ADOLESCENT DRINKING IN THE UNITED STATES AND IRELAND
    Joel Grube; Fiscal Year: 1993
    ....
  70. CHEMICAL RELEASE & IMMUNE SENSITIZATION BY DENTAL RESINS
    Anahid Jewett; Fiscal Year: 2002
    ..The studies described will help to prevent and treat adverse effects of this class of dental materials. ..
  71. Electronic/Molecular Structure of Enzyme Heme Pockets
    GERD LA MAR; Fiscal Year: 2009
    ..The elucidation of the similarities and differences between bacterial and mammalian heme oxygenase will improve prospects for the design of selective inhibitors for the enzyme in pathogenic bacteria. ..
  72. Dental Cast Titanium-Ceramic Bonding
    Zhuo Cai; Fiscal Year: 2003
    ..This development will advance the titanium-ceramic systems that are more biocompatible and economical than current metal-ceramic systems, thereby benefitting the general public. ..