choice behavior

Summary

Summary: The act of making a selection among two or more alternatives, usually after a period of deliberation.

Top Publications

  1. ncbi Impulsivity, compulsivity, and top-down cognitive control
    Jeffrey W Dalley
    Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge CB23EB, UK
    Neuron 69:680-94. 2011
  2. ncbi The time course of perceptual choice: the leaky, competing accumulator model
    M Usher
    Department of Psychology, Birkbeck College, University of London, England
    Psychol Rev 108:550-92. 2001
  3. ncbi Self-control in decision-making involves modulation of the vmPFC valuation system
    Todd A Hare
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Science 324:646-8. 2009
  4. ncbi The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry
    T W Robbins
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Psychopharmacology (Berl) 163:362-80. 2002
  5. ncbi The physics of optimal decision making: a formal analysis of models of performance in two-alternative forced-choice tasks
    Rafal Bogacz
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ, USA
    Psychol Rev 113:700-65. 2006
  6. ncbi Choice, uncertainty and value in prefrontal and cingulate cortex
    Matthew F S Rushworth
    Department of Experimental Psychology and Centre for Functional MRI of the Brain, John Radcliffe Hospital, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
    Nat Neurosci 11:389-97. 2008
  7. ncbi Conducting discrete choice experiments to inform healthcare decision making: a user's guide
    Emily Lancsar
    Business School Economics and Institute of Health and Society, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Pharmacoeconomics 26:661-77. 2008
  8. pmc Frames, biases, and rational decision-making in the human brain
    Benedetto De Martino
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1 3AR, UK
    Science 313:684-7. 2006
  9. pmc Model-based influences on humans' choices and striatal prediction errors
    Nathaniel D Daw
    Center for Neural Science and Department of Psychology, New York University, New York, NY 10012, USA
    Neuron 69:1204-15. 2011
  10. ncbi Neural economics and the biological substrates of valuation
    P Read Montague
    Center for Theoretical Neuroscience, Human Neuroimaging Lab, Division of Neuroscience, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA
    Neuron 36:265-84. 2002

Detail Information

Publications368 found, 100 shown here

  1. ncbi Impulsivity, compulsivity, and top-down cognitive control
    Jeffrey W Dalley
    Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge CB23EB, UK
    Neuron 69:680-94. 2011
    ..These results indicate that the vulnerability to stimulant addiction may depend on an impulsivity endophenotype. Implications of these findings for the etiology, development, and treatment of drug addiction are considered...
  2. ncbi The time course of perceptual choice: the leaky, competing accumulator model
    M Usher
    Department of Psychology, Birkbeck College, University of London, England
    Psychol Rev 108:550-92. 2001
    ..The model captures choice behavior regardless of the number of alternatives, accounting for the log-linear relation between reaction time and ..
  3. ncbi Self-control in decision-making involves modulation of the vmPFC valuation system
    Todd A Hare
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Science 324:646-8. 2009
    ..It incorporated both taste and health in self-controllers but only taste in non-self-controllers. Activity in DLPFC increased when subjects exercised self-control and correlated with activity in vmPFC...
  4. ncbi The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry
    T W Robbins
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Psychopharmacology (Berl) 163:362-80. 2002
    ..The developmental history and application of the 5-choice serial reaction time task (5CSRTT) for measuring effects of drugs and other manipulations on attentional performance (and stimulus control) in rats is reviewed...
  5. ncbi The physics of optimal decision making: a formal analysis of models of performance in two-alternative forced-choice tasks
    Rafal Bogacz
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ, USA
    Psychol Rev 113:700-65. 2006
    ..They use these findings to address empirical data and make novel predictions about performance under optimality...
  6. ncbi Choice, uncertainty and value in prefrontal and cingulate cortex
    Matthew F S Rushworth
    Department of Experimental Psychology and Centre for Functional MRI of the Brain, John Radcliffe Hospital, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
    Nat Neurosci 11:389-97. 2008
    ....
  7. ncbi Conducting discrete choice experiments to inform healthcare decision making: a user's guide
    Emily Lancsar
    Business School Economics and Institute of Health and Society, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Pharmacoeconomics 26:661-77. 2008
    ..Thus, they offer viable alternatives and complements to existing methods of valuation and preference elicitation...
  8. pmc Frames, biases, and rational decision-making in the human brain
    Benedetto De Martino
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1 3AR, UK
    Science 313:684-7. 2006
    ..This finding highlights the importance of incorporating emotional processes within models of human choice and suggests how the brain may modulate the effect of these biasing influences to approximate rationality...
  9. pmc Model-based influences on humans' choices and striatal prediction errors
    Nathaniel D Daw
    Center for Neural Science and Department of Psychology, New York University, New York, NY 10012, USA
    Neuron 69:1204-15. 2011
    ..We designed a multistep decision task in which model-based and model-free influences on human choice behavior could be distinguished...
  10. ncbi Neural economics and the biological substrates of valuation
    P Read Montague
    Center for Theoretical Neuroscience, Human Neuroimaging Lab, Division of Neuroscience, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA
    Neuron 36:265-84. 2002
    ....
  11. pmc States versus rewards: dissociable neural prediction error signals underlying model-based and model-free reinforcement learning
    Jan Gläscher
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91101, USA
    Neuron 66:585-95. 2010
    ..This finding supports the existence of two unique forms of learning signal in humans, which may form the basis of distinct computational strategies for guiding behavior...
  12. ncbi Human insula activation reflects risk prediction errors as well as risk
    Kerstin Preuschoff
    Computation and Neural Systems Program and Division of Humanities and Social Sciences, Caltech, Pasadena, California 91125, USA
    J Neurosci 28:2745-52. 2008
    ..As such, our findings indicate that our understanding of the neural basis of reward anticipation under uncertainty needs to be expanded to include risk prediction...
  13. ncbi The use of multiple cues in mate choice
    Ulrika Candolin
    Department of Ecology and Systematics, P O Box 65, University of Helsinki, Helsinki FIN 00014, Finland
    Biol Rev Camb Philos Soc 78:575-95. 2003
    ..Finally I discuss the consequences that the use of multiple cues may have for the process of sexual selection, the maintenance of genetic variation, and speciation...
  14. ncbi Matching behavior and the representation of value in the parietal cortex
    Leo P Sugrue
    Howard Hughes Medical Institute and Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 304:1782-7. 2004
    ..We found that a simple model based on reward history can duplicate this behavior and that neurons in the parietal cortex represent the relative value of competing actions predicted by this model...
  15. ncbi Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits
    J D Salamone
    Division of Behavioral Neuroscience, Department of Psychology, University of Connecticut, Storrs, CT, 06269 1020, USA
    Psychopharmacology (Berl) 191:461-82. 2007
    ....
  16. ncbi Discrete choice experiments in health economics: a review of the literature
    Esther W de Bekker-Grob
    Department of Public Health, Erasmus MC University Medical Centre, Rotterdam, The Netherlands
    Health Econ 21:145-72. 2012
    ..Incorporation of interactions terms in the design and analysis of DCEs, explanations of risk, tests of external validity and incorporation of DCE results into a decision-making framework remain important areas for future research...
  17. ncbi Failure to detect mismatches between intention and outcome in a simple decision task
    Petter Johansson
    Lund University Cognitive Science, Lund University, Kungshuset Lundagård, 222 22 Lund, Sweden
    Science 310:116-9. 2005
    ..We call this effect choice blindness...
  18. ncbi Speed and accuracy of olfactory discrimination in the rat
    Naoshige Uchida
    Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA
    Nat Neurosci 6:1224-9. 2003
    ....
  19. ncbi Tonic dopamine: opportunity costs and the control of response vigor
    Yael Niv
    Interdisciplinary Center for Neural Computation, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel
    Psychopharmacology (Berl) 191:507-20. 2007
    ....
  20. ncbi Lateral prefrontal cortex and self-control in intertemporal choice
    Bernd Figner
    Center for Decision Sciences, Columbia University, New York, New York, USA
    Nat Neurosci 13:538-9. 2010
    ..rTMS did not change choices involving only delayed rewards or valuation judgments of immediate and delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex-based self-control mechanism in intertemporal choice...
  21. pmc Cortical substrates for exploratory decisions in humans
    Nathaniel D Daw
    Gatsby Computational Neuroscience Unit, University College London UCL, Alexandra House, 17 Queen Square, London WC1N 3AR, UK
    Nature 441:876-9. 2006
    ....
  22. ncbi Sexual selection and mate choice
    Malte Andersson
    Department of Zoology, University of Gothenburg, SE 405 30 Gothenburg, Sweden
    Trends Ecol Evol 21:296-302. 2006
    ..We identify where new techniques can help estimate the relative roles of the various selection mechanisms that might work together in the evolution of mating preferences and attractive traits, and in sperm-egg interactions...
  23. pmc Effort-based cost-benefit valuation and the human brain
    Paula L Croxson
    Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Neurosci 29:4531-41. 2009
    ..The ventral striatum and anterior cingulate cortex may be the substrate of effort-based cost-benefit valuation in primates as well as in rats...
  24. ncbi Independent coding of reward magnitude and valence in the human brain
    Nick Yeung
    Center for the Study of Brain, Mind, and Behavior, Department of Psychology, Princeton University, Princeton, New Jersey 08544, USA
    J Neurosci 24:6258-64. 2004
    ....
  25. pmc Neural mechanisms of foraging
    Nils Kolling
    Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
    Science 336:95-8. 2012
    ..Whereas vmPFC encodes values of specific well-defined options, ACC encodes the average value of the foraging environment and cost of foraging...
  26. pmc Risky business: the neuroeconomics of decision making under uncertainty
    Michael L Platt
    Center for Neuroeconomic Studies, Room B243F LSRC Building, Duke University, Durham, North Carolina 27708 0999, USA
    Nat Neurosci 11:398-403. 2008
    ..Thus, understanding decision making-indeed, understanding behavior itself-requires knowing how the brain responds to and uses information about uncertainty...
  27. ncbi Overlapping and distinct neural systems code for subjective value during intertemporal and risky decision making
    Jan Peters
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
    J Neurosci 29:15727-34. 2009
    ..making, valuation of different types of rewards may involve partially distinct neural systems, but efficient choice behavior requires a common neural coding of stimulus value...
  28. ncbi Fairness versus reason in the ultimatum game
    M A Nowak
    Institute for Advanced Study, Einstein Drive, Princeton, NJ 08540, USA
    Science 289:1773-5. 2000
    ..We show that fairness will evolve if the proposer can obtain some information on what deals the responder has accepted in the past. Hence, the evolution of fairness, similarly to the evolution of cooperation, is linked to reputation...
  29. pmc Counterfactual choice and learning in a neural network centered on human lateral frontopolar cortex
    Erie D Boorman
    Department of Experimental Psychology, University of Oxford, Oxford, UK
    PLoS Biol 9:e1001093. 2011
    ..Taken together, these data provide both neural and behavioral evidence to support the existence of a previously unidentified neural system responsible for tracking both counterfactual choice options and their outcomes...
  30. pmc The cost of accumulating evidence in perceptual decision making
    Jan Drugowitsch
    Institut National de la Sante et de la Recherche Medicale, Ecole Normale Superieure, 75005 Paris, France
    J Neurosci 32:3612-28. 2012
    ..The theory also correctly predicts that urgency signals in the brain should be independent of the difficulty, or stimulus strength, at each trial...
  31. ncbi "I had so much it didn't seem fair": Eight-year-olds reject two forms of inequity
    Peter R Blake
    Graduate School of Education, Harvard University, 510 Larsen Hall, 14 Appian Way, Cambridge, MA 02138, United States
    Cognition 120:215-24. 2011
    ..By contrast, 8-year-olds rejected both forms of inequity. These results suggest that two distinct mechanisms underlie the development of the two forms of inequity aversion...
  32. ncbi The neural basis of financial risk taking
    Camelia M Kuhnen
    Stanford Graduate School of Business, 518 Memorial Way, S479, Stanford, California, 94305, USA
    Neuron 47:763-70. 2005
    ..Thus, consideration of anticipatory neural mechanisms may add predictive power to the rational actor model of economic decision making...
  33. pmc Neural substrates of reward magnitude, probability, and risk during a wheel of fortune decision-making task
    Bruce W Smith
    Department of Psychology, University of New Mexico, USA
    Neuroimage 44:600-9. 2009
    ..In addition, this paradigm further clarifies the functional specialization of the cingulate cortex in processes of decision-making...
  34. pmc The neural substrates of probabilistic and intertemporal decision making
    Bethany J Weber
    Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA
    Brain Res 1234:104-15. 2008
    ..These results indicate that there are differences in the patterns of brain activation evoked by risky and intertemporal choices, suggesting that the two domains utilize at least partially distinct sets of cognitive processes...
  35. ncbi Episodic future thinking reduces reward delay discounting through an enhancement of prefrontal-mediotemporal interactions
    Jan Peters
    NeuroimageNord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Neuron 66:138-48. 2010
    ..imagery during cue processing predicted how much subjects changed their preferences toward more future-minded choice behavior. Neural valuation signals in the anterior cingulate cortex and functional coupling of this region with ..
  36. ncbi Selection of effective stone tools by wild bearded capuchin monkeys
    Elisabetta Visalberghi
    Unit of Cognitive Primatology and Primate Center, Institute of Cognitive Sciences and Technologies, CNR, Rome, Italy
    Curr Biol 19:213-7. 2009
    ..Thus, planning actions and intentional selection of tools is within the ken of monkeys and similar to the tool activities of hominins and apes...
  37. ncbi Disruption of right prefrontal cortex by low-frequency repetitive transcranial magnetic stimulation induces risk-taking behavior
    Daria Knoch
    Department of Neurology, PET Center, Division of Nuclear Medicine, University Hospital Zurich, 8091 Zurich, Switzerland
    J Neurosci 26:6469-72. 2006
    ..The ability to modify risk-taking behavior may be translated into therapeutic interventions for disorders such as drug abuse or pathological gambling...
  38. ncbi The proactive brain: using analogies and associations to generate predictions
    Moshe Bar
    Martinos Center for Biomedical Imaging at MGH, Harvard Medical School, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Trends Cogn Sci 11:280-9. 2007
    ..This cognitive neuroscience framework can help explain a variety of phenomena, ranging from recognition to first impressions, and from the brain's 'default mode' to a host of mental disorders...
  39. pmc Congruence of BOLD response across intertemporal choice conditions: fictive and real money gains and losses
    Warren K Bickel
    Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    J Neurosci 29:8839-46. 2009
    ....
  40. ncbi Employment preferences of public sector nurses in Malawi: results from a discrete choice experiment
    Lindsay J Mangham
    Health Economics and Financing Programme, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 13:1433-41. 2008
    ..To understand the employment preferences of Malawian public sector registered nurses, and to ascertain whether salary increases significantly affect how nurses regard their employment...
  41. ncbi Horse-race model simulations of the stop-signal procedure
    Guido P H Band
    Department of Psychology, Faculty of Psychology, Leiden University, PO Box 9555, 2300 RB Leiden, The Netherlands
    Acta Psychol (Amst) 112:105-42. 2003
    ..The simulations indicate that, under most conditions, the latency, but not variability, of response inhibition can be reliably estimated...
  42. ncbi Regret and its avoidance: a neuroimaging study of choice behavior
    Giorgio Coricelli
    Neuropsychology Group, Institut des Sciences Cognitives, Centre National de la Recherche Scientifique, 67 Boulevard Pinel 69675, Bron, France
    Nat Neurosci 8:1255-62. 2005
    ..These results demonstrate that medial orbitofrontal cortex modulates the gain of adaptive emotions in a manner that may provide a substrate for the influence of high-level emotions on decision making...
  43. ncbi The involvement of the orbitofrontal cortex in the experience of regret
    Nathalie Camille
    Institut des Sciences Cognitives, CNRS, 67, Boulevard Pinel 69675 Bron, France
    Science 304:1167-70. 2004
    ..Patients with orbitofrontal cortical lesions, however, did not report regret or anticipate negative consequences of their choices. The orbitofrontal cortex has a fundamental role in mediating the experience of regret...
  44. pmc Discrete choice experiments in health care
    Mandy Ryan
    BMJ 328:360-1. 2004
  45. ncbi Neural processing of risk
    Peter N C Mohr
    Neurocognition of Decision Making Group, Max Planck Institute for Human Development, D 14195 Berlin, Germany
    J Neurosci 30:6613-9. 2010
    ..The anterior insula was predominantly active in the presence of potential losses, indicating that potential losses modulate risk processing...
  46. ncbi Optimal decision-making theories: linking neurobiology with behaviour
    Rafal Bogacz
    Department of Computer Science, University of Bristol, Bristol BS8 1UB, UK
    Trends Cogn Sci 11:118-25. 2007
    ..This review illustrates how optimal-decision theories elucidate current data and provide experimental predictions that concern both neurobiology and behaviour...
  47. pmc Free choice activates a decision circuit between frontal and parietal cortex
    Bijan Pesaran
    Center for Neural Science, New York University, New York, New York 10003, USA
    Nature 453:406-9. 2008
    ..Cells participating in this decision circuit may influence movement choices by providing a common bias to the selection of movement goals...
  48. pmc A comparison of sequential sampling models for two-choice reaction time
    Roger Ratcliff
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Psychol Rev 111:333-67. 2004
    ..The relationship between these models and 3 recent, neurally inspired models was also examined...
  49. pmc Is choice-induced preference change long lasting?
    Tali Sharot
    Department of Cognitive, Perceptual and Brain Sciences, University College London, London, England
    Psychol Sci 23:1123-9. 2012
    ..Our findings provide evidence that making a decision can lead to enduring change in preferences...
  50. ncbi The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats
    Andrea Bari
    Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, UK
    Nat Protoc 3:759-67. 2008
    ....
  51. ncbi The good, the bad and the neutral: electrophysiological responses to feedback stimuli
    Clay B Holroyd
    Department of Psychology University of Victoria, PO Box 3050 STN CSC Victoria, Canada BC V8W 3P5
    Brain Res 1105:93-101. 2006
    ..This result is consistent with recent proposals that the evaluative system that produces the fERN classifies outcomes into two categories: those outcomes that indicate that a goal has been satisfied and those that do not...
  52. ncbi The P300 and reward valence, magnitude, and expectancy in outcome evaluation
    Yan Wu
    Research Center for Learning Science, Southeast University, Nanjing 210096, China
    Brain Res 1286:114-22. 2009
    ....
  53. pmc Lifting the veil of morality: choice blindness and attitude reversals on a self-transforming survey
    Lars Hall
    Lund University Cognitive Science, Lund University, Lund, Sweden
    PLoS ONE 7:e45457. 2012
    ..These results suggest a dramatic potential for flexibility in our moral attitudes, and indicates a clear role for self-attribution and post-hoc rationalization in attitude formation and change...
  54. ncbi The description-experience gap in risky choice
    Ralph Hertwig
    University of Basel, Department of Psychology, Missionsstrasse 60 62, CH 4055 Basel, Switzerland
    Trends Cogn Sci 13:517-23. 2009
    ..Striking similarities in human and animal experience-based choices, ways of modeling these choices, and their implications for risk and precautionary behavior are discussed...
  55. ncbi Do fish count? Spontaneous discrimination of quantity in female mosquitofish
    Christian Agrillo
    Department of General Psychology, University of Padova, Via Venezia 8, 35131, Padua, Italy
    Anim Cogn 11:495-503. 2008
    ....
  56. ncbi Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activity
    Ahmad R Hariri
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Neurosci 26:13213-7. 2006
    ..They also highlight a specific neurocognitive mechanism that may contribute to increased risk for addiction...
  57. ncbi The simplest complete model of choice response time: linear ballistic accumulation
    Scott D Brown
    School of Psychology, University of Newcastle, Callaghan, NSW 2308, Australia
    Cogn Psychol 57:153-78. 2008
    ..Our results are encouraging in a field beset by the tradeoff between complexity and completeness...
  58. pmc Dynamic response-by-response models of matching behavior in rhesus monkeys
    Brian Lau
    Center for Neural Science, New York University, New York, New York 10003, USA
    J Exp Anal Behav 84:555-79. 2005
    We studied the choice behavior of 2 monkeys in a discrete-trial task with reinforcement contingencies similar to those Herrnstein (1961) used when he described the matching law...
  59. pmc Dopamine neurons encode the better option in rats deciding between differently delayed or sized rewards
    Matthew R Roesch
    Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn Street, HSF 2 S251, Baltimore, Maryland 21201, USA
    Nat Neurosci 10:1615-24. 2007
    ..Moreover, when rats were given a choice between two differently valued outcomes, the activity of the neurons initially reflected the more valuable option, even when it was not subsequently selected...
  60. ncbi Nutrition Environment Measures Survey in stores (NEMS-S): development and evaluation
    Karen Glanz
    Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    Am J Prev Med 32:282-9. 2007
    ..There is a need for valid, reliable measures of nutrition environments. This article reports on the development and evaluation of measures of nutrition environments in retail food stores...
  61. pmc Separable learning systems in the macaque brain and the role of orbitofrontal cortex in contingent learning
    Mark E Walton
    Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
    Neuron 65:927-39. 2010
    ..This pattern of choice behavior could be explained by a causal role for OFC in appropriate contingent learning, the process by which causal ..
  62. pmc Heterogeneous coding of temporally discounted values in the dorsal and ventral striatum during intertemporal choice
    Xinying Cai
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Neuron 69:170-82. 2011
    ..These results suggest a more pivotal role for the dorsal striatum in action selection during intertemporal choice...
  63. pmc Neuromarketing: the hope and hype of neuroimaging in business
    Dan Ariely
    Dan Ariely is at the Fuqua School of Business, Center for Cognitive Neuroscience, Department of Economics, and the Department of Psychiatry and Behavioural Sciences, Duke University, Durham, North Carolina 2770, USA
    Nat Rev Neurosci 11:284-92. 2010
    ..The most promising application of neuroimaging methods to marketing may come before a product is even released - when it is just an idea being developed...
  64. ncbi Neural responses to unattended products predict later consumer choices
    Anita Tusche
    Bernstein Center for Computational Neuroscience Berlin, Charite Universitatsmedizin Berlin, 10115 Berlin, Germany
    J Neurosci 30:8024-31. 2010
    ..Overall, the present findings emphasize the potential of implicit, automatic processes in guiding even important and complex decisions...
  65. ncbi Similar effects of the selective noradrenaline reuptake inhibitor atomoxetine on three distinct forms of impulsivity in the rat
    Emma S J Robinson
    Department of Experimental Psychology, Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge, UK
    Neuropsychopharmacology 33:1028-37. 2008
    ....
  66. ncbi How actions create--not just reveal--preferences
    Dan Ariely
    Duke University, One Towerview Road, Durham, NC 27708, USA
    Trends Cogn Sci 12:13-6. 2008
    ..Here we review the roles of these streams of utility in shaping preferences, and discuss how neuroimaging offers unique possibilities for disentangling their independent contributions to behavior...
  67. pmc Neural computations underlying action-based decision making in the human brain
    Klaus Wunderlich
    Computation and Neural Systems Program, California Institute of Technology, Pasadena, CA, USA
    Proc Natl Acad Sci U S A 106:17199-204. 2009
    ..Furthermore, we also found signals in the dorsomedial frontal cortex that resemble the output of a decision comparator, which implicates this region in the computation of the decision itself...
  68. ncbi An urban food store intervention positively affects food-related psychosocial variables and food behaviors
    Joel Gittelsohn
    Johns Hopkins University, Bloomberg School of Public Health, Department of International Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    Health Educ Behav 37:390-402. 2010
    ..This is the first food store intervention trial in low-income urban communities to show positive impacts at the consumer level...
  69. pmc Medial prefrontal cortex as an action-outcome predictor
    William H Alexander
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA
    Nat Neurosci 14:1338-44. 2011
    ..Cognitive control at the neural level is then seen as a result of evaluating the probable and actual outcomes of one's actions...
  70. ncbi Sensitivity of electrophysiological activity from medial frontal cortex to utilitarian and performance feedback
    Sander Nieuwenhuis
    Department of Psychology, Princeton University, NJ, USA
    Cereb Cortex 14:741-7. 2004
    ..The results are consistent with the view that the two components are manifestations of the same underlying cognitive and neural process...
  71. ncbi Behavioural characterisation of high impulsivity on the 5-choice serial reaction time task: specific deficits in 'waiting' versus 'stopping'
    E S J Robinson
    Behavioural and Clinical Neuroscience Institute and Department of Experimental Psychology, Cambridge, UK
    Behav Brain Res 196:310-6. 2009
    ..We thus suggest that an inability to bridge delays to future rewards and reward-related stimuli is a candidate behavioural endophenotype that pre-disposes to clinical psychopathology...
  72. pmc A discounting framework for choice with delayed and probabilistic rewards
    Leonard Green
    Department of Psychology, Washington University, St Louis, MO 63130, USA
    Psychol Bull 130:769-92. 2004
    ..The present effort illustrates the value of studying choice involving both delayed and probabilistic outcomes within a general discounting framework that uses similar experimental procedures and a common analytical approach...
  73. ncbi Critical involvement of dopaminergic neurotransmission in impulsive decision making
    Marcel M van Gaalen
    Department of Medical Pharmacology, Research Institute Neurosciences Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Free University Medical Center, Amsterdam, The Netherlands
    Biol Psychiatry 60:66-73. 2006
    ..Commonly prescribed for this condition, amphetamine (Adderall), reduces impulsive decision making; however, the neuropharmacologic mechanism of this effect of amphetamine is unclear...
  74. ncbi Decisions from experience and the effect of rare events in risky choice
    Ralph Hertwig
    University of Basel, Basel, Switzerland
    Psychol Sci 15:534-9. 2004
    ..Decisions from experience and decisions from description can lead to dramatically different choice behavior. In the case of decisions from description, people make choices as if they overweight the probability of rare ..
  75. pmc Mechanisms underlying dopamine-mediated reward bias in compulsive behaviors
    Valerie Voon
    National Institutes of Health, Bethesda, MD 20892 1428, USA
    Neuron 65:135-42. 2010
    ..Thus, our findings are consistent with a model whereby a distorted estimation of the gain cue underpins a choice bias toward gains...
  76. ncbi Summation and quantity judgments of sequentially presented sets by capuchin monkeys (Cebus apella)
    Michael J Beran
    Language Research Center, Georgia State University, Atlanta, Georgia 30303, USA
    Am J Primatol 70:191-4. 2008
    ..Capuchins also inhibit responses to visible food items when those items are only part of an overall smaller quantity of food compared with a completely nonvisible set...
  77. ncbi Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls
    K N Kirby
    Department of Psychology, Bronfman Science Center, Williams College, Williamstown, Massachusetts 01267, USA
    J Exp Psychol Gen 128:78-87. 1999
    ..05). The results lend external validity to the delay-discounting rate as a measure of impulsiveness, a characteristic associated with substance abuse...
  78. ncbi Neuroeconomics: the consilience of brain and decision
    Paul W Glimcher
    Center for Neural Science, New York University, New York, NY 10003, USA
    Science 306:447-52. 2004
    ..This review describes recent developments in neuroeconomics from both behavioral and biological perspectives...
  79. ncbi Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional task
    J W Dalley
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom CB2 3EB
    J Neurosci 21:4908-14. 2001
    ....
  80. pmc Encoding of time-discounted rewards in orbitofrontal cortex is independent of value representation
    Matthew R Roesch
    Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn Street, HSF 2 S251, Baltimore, 21201, USA
    Neuron 51:509-20. 2006
    ....
  81. ncbi Functional dissociation in frontal and striatal areas for processing of positive and negative reward information
    Xun Liu
    Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky 40536, USA
    J Neurosci 27:4587-97. 2007
    ..These distinct but interactive systems may serve to guide human's reward-seeking behavior...
  82. ncbi Cortical and subcortical contributions to Stop signal response inhibition: role of the subthalamic nucleus
    Adam R Aron
    Department of Psychology, Brain Research Institute, University of California, Los Angeles, California 90095, USA
    J Neurosci 26:2424-33. 2006
    ..Future research is required to establish whether Stop-signal inhibition could be implemented via a direct functional neuroanatomic projection between IFC and STN (a "hyperdirect" pathway)...
  83. pmc Dopaminergic modulation of effort-related choice behavior as assessed by a progressive ratio chow feeding choice task: pharmacological studies and the role of individual differences
    Patrick A Randall
    Department of Psychology, University of Connecticut, Storrs, United States of America
    PLoS ONE 7:e47934. 2012
    ..Furthermore, accumbens core signal transduction activity is related to individual differences in work output...
  84. pmc Alterations in choice behavior by manipulations of world model
    C S Green
    Department of Psychology, Center for Cognitive Science, University of Minnesota, Minneapolis, MN 55455, USA
    Proc Natl Acad Sci U S A 107:16401-6. 2010
    ..Here we show that (i) "probability matching"-a consistent example of suboptimal choice behavior seen in humans-occurs in an optimal Bayesian model-based learner using a max decision rule that is ..
  85. pmc Confidence in value-based choice
    Benedetto De Martino
    Psychology and Language Sciences, University College London, London, UK
    Nat Neurosci 16:105-10. 2013
    ..Our findings provide a mechanistic link between noise in value comparison and metacognitive awareness of choice, enabling us both to want and to express knowledge of what we want...
  86. ncbi Using discrete choice experiments to value health care programmes: current practice and future research reflections
    Mandy Ryan
    Health Economics Research Unit, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
    Appl Health Econ Health Policy 2:55-64. 2003
    ..It is also critical to link, more generally, the research agenda to work being carried out in marketing, transport and environmental economics and health economics benefit assessment...
  87. pmc Dissociable neural representations of future reward magnitude and delay during temporal discounting
    Kacey Ballard
    Department of Psychology, Stanford University, CA 94305, USA
    Neuroimage 45:143-50. 2009
    ....
  88. ncbi Representation of others' action by neurons in monkey medial frontal cortex
    Kyoko Yoshida
    Laboratory for Symbolic Cognitive Development, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan
    Curr Biol 21:249-53. 2011
    ..We suggest that the MFC is involved in self-other differentiation in the domain of motor action and provides a fundamental neural signal for social learning...
  89. pmc Distributed coding of actual and hypothetical outcomes in the orbital and dorsolateral prefrontal cortex
    Hiroshi Abe
    Department of Neurobiology, Yale University, New Haven, CT 06510, USA
    Neuron 70:731-41. 2011
    ..Conjunctive and parallel coding of multiple actions and their outcomes in the prefrontal cortex might enhance the efficiency of reinforcement learning and also contribute to their context-dependent memory...
  90. pmc Mapping value based planning and extensively trained choice in the human brain
    Klaus Wunderlich
    Wellcome Trust Center for Neuroimaging, University College London, London, UK
    Nat Neurosci 15:786-91. 2012
    ..Our findings point toward an architecture of choice in which segregated value systems operate in parallel in the striatum for planning and extensively trained choices, with medial prefrontal cortex integrating their outputs...
  91. pmc Fictive reward signals in the anterior cingulate cortex
    Benjamin Y Hayden
    Department of Neurobiology, Duke University School of Medicine, Center for Neuroeconomic Studies, Center for Cognitive Neuroscience, Duke University, Durham, NC 27701, USA
    Science 324:948-50. 2009
    ..We found that ACC neurons signal fictive reward information and use a coding scheme similar to that used to signal experienced outcomes. Thus, individual ACC neurons process both experienced and fictive rewards...
  92. pmc Dopamine enhances model-based over model-free choice behavior
    Klaus Wunderlich
    Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, UK
    Neuron 75:418-24. 2012
    ..We found increased dopamine levels promote model-based over model-free choice...
  93. pmc Differentiable neural substrates for learned and described value and risk
    Thomas H B FitzGerald
    Wellcome Trust Centre for Neuroimaging, 12 Queen Square, London, UK
    Curr Biol 20:1823-9. 2010
    ..Our data indicate that, during decision making under risk, both behavior and the neural encoding of key decision variables are strongly influenced by the manner in which value information is presented...
  94. pmc A 2-phase labeling and choice architecture intervention to improve healthy food and beverage choices
    Anne N Thorndike
    General Medicine Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Public Health 102:527-33. 2012
    ..We assessed whether a 2-phase labeling and choice architecture intervention would increase sales of healthy food and beverages in a large hospital cafeteria...
  95. ncbi Representation of action-specific reward values in the striatum
    Kazuyuki Samejima
    Department of Computational Neurobiology, ATR Computational Neuroscience Laboratories, 619 0288 Kyoto, Japan
    Science 310:1337-40. 2005
    ..Fewer neurons were tuned to relative values or action choice. These results suggest representation of action values in the striatum, which can guide action selection in the basal ganglia circuit...
  96. pmc Instructional control of reinforcement learning: a behavioral and neurocomputational investigation
    Bradley B Doll
    Department of Cognitive and Linguistic Sciences, Department of Psychology, Brown University, USA
    Brain Res 1299:74-94. 2009
    ..Despite experience to the contrary, instructions drove choice behavior. We present neural network simulations that capture the interactions between instruction-driven and ..
  97. ncbi L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease
    Roshan Cools
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB3 9DF, UK
    Neuropsychologia 41:1431-41. 2003
    ....
  98. ncbi Hypothetical and real choice differentially activate common valuation areas
    Min Jeong Kang
    Haas School of Business, University of California, Berkeley, California 94720, USA
    J Neurosci 31:461-8. 2011
    ....
  99. ncbi Dopaminergic modulation of the orbitofrontal cortex affects attention, motivation and impulsive responding in rats performing the five-choice serial reaction time task
    Catharine A Winstanley
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Behav Brain Res 210:263-72. 2010
    ..Furthermore, D(2)-mediated neurotransmission within the OFC could make a more fundamental contribution to cognitive behaviour...
  100. ncbi Magic at the marketplace: Choice blindness for the taste of jam and the smell of tea
    Lars Hall
    Lund University Cognitive Science, Lund University, Sweden
    Cognition 117:54-61. 2010
    ....
  101. ncbi Sub-optimal performance in the 5-choice serial reaction time task in rats was sensitive to methylphenidate, atomoxetine and d-amphetamine, but unaffected by the COMT inhibitor tolcapone
    Neil E Paterson
    Behavioral Pharmacology, PsychoGenics, Inc, Tarrytown, NY 10591, USA
    Neurosci Res 69:41-50. 2011
    ..Finally, tolcapone had no effects on sub-optimal performance in the variable ITI 5-CSRTT. These results suggest minimal potential of tolcapone as a therapeutic agent for ADHD and implicate cortical NE, not DA, in impulsive action...

Research Grants63

  1. Mechanisms of glucosensation mediating food choice behavior in Drosophila
    Monica Dus; Fiscal Year: 2013
    ..During my postdoctoral studies I developed an assay to study food choice behavior in Drosophila and found that flies are equipped with a mechanism to detect the nutritional value of food ..
  2. Impact of Receptor Polymorphisms on Sensations from Common Oral Irritants
    JOHN EDWARD HAYES; Fiscal Year: 2013
    ..Proposed work may also provide new insight with respect to food choice behavior or causes of oral pathologies that involve burning sensations...
  3. Cocaine disruption of maternal motivation: preference for pups vs. cocaine
    MARIANA PEREIRA ARBOLEYA; Fiscal Year: 2010
    ..the causal contribution of dopamine (DA) and glutamate (GLU) neurotransmission within key regions to the choice behavior will be determined with site- specific infusion of selective DA and GLU agonists and/or antagonists (Specific ..
  4. Development of rat models of the effort-related symptoms of depression
    John D Salamone; Fiscal Year: 2013
    ..various neurotransmitters, such as dopamine (DA) and adenosine, in the exertion of effort and effort-related choice behavior. Considerable evidence indicates that these basic studies in animals are potentially relevant for ..
  5. Functional Neuroanatomy of Approach and Avoidance Behavior
    EDWARD CLIFTON HURLOCK; Fiscal Year: 2010
    ..The overall hypothesis to be evaluated is that light/dark preference, a non-reflexive choice behavior, is controlled by discrete populations of neurons...
  6. The Computational Basis of Theory of Mind in the Human Brain
    DAMIAN ALEXANDER STANLEY; Fiscal Year: 2013
    ..modeling techniques to generate testable predictions about the specific computations underlying learning and choice behavior. This computational approach has specific advantages over traditional psychological methods...
  7. Neural Mechanisms of Risk Preference Following Adolescent Alcohol Exposure
    Jeremy J Clark; Fiscal Year: 2013
    ..that changes in phasic dopamine release, as a consequence of alcohol exposure, could underlie biases in choice behavior and promote risk preference...
  8. THE ROLE OF PREFRONTAL REGIONS IN ECONOMIC CHOICE AND CHOICE-GUIDED BEHAVIOR
    Camillo Padoa-Schioppa; Fiscal Year: 2013
    ..While these disorders disrupt choice behavior in a variety of domains - including food, money, intertemporal choices, social choices, etc...
  9. Timing, reward processing and choice
    Kimberly Kirkpatrick; Fiscal Year: 2013
    ..to implement screening methods for identifying the underlying source of individual differences in impulsive choice behavior, to develop targeted therapeutic techniques for improving deficits in reward processing and temporal ..
  10. CRCNS:Investigating perceptual processing speed and its impact on choice behavior
    Terrence R Stanford; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The neurobiology of choice behavior has been intensely studied with laboratory tasks in which a subject makes a perceptual judgement and indicates the result with a motor action...
  11. Dopaminergic Modulation of Subjective Valuation across Adulthood
    David H Zald; Fiscal Year: 2013
    ..All participants will complete decision making tasks while undergoing fMRI to test whether differences in choice behavior and functional neural activity are influenced by age differences in D2-like receptor levels...
  12. SNRP PROJECT AT MEHARRY MEDICAL COLLEGE
    CLIVEL CHARLTON; Fiscal Year: 2010
    ..data, and communicating these findings in oral and written form to achieve the individual success of these investigators and to strengthen the portfolio of bench to bedside neuroscience research at MMC and with its Alliance partner, VUMC ..
  13. Neural Basis of Perceiving Control: Implications for Emotion Regulation
    LAUREN AIMEE LEOTTI; Fiscal Year: 2012
    ..In the proposed studies, perceived control is operationalized as the opportunity to exercise choice, since choice behavior is the means by which organisms exert control over their environments (e.g...
  14. Neurobiological Bases of Economic Choice Behavior
    Camillo Padoa Schioppa; Fiscal Year: 2010
    ..b>Choice behavior is a traditional focus in economics and psychology...
  15. Social Stress: Vulnerability to Cocaine Abuse in Monkeys
    Michael A Nader; Fiscal Year: 2013
    ..how environmental and pharmacological variables contribute to vulnerability, maintenance, relapse and choice behavior involving drugs of abuse. Such information will lead to better treatment and prevention strategies...
  16. Synthesis of Incongruent Temporal Information
    Matthew S Matell; Fiscal Year: 2011
    ..The current project examines temporal memory synthesis across drug states, and the involvement of memory synthesis in choice behavior.
  17. Social Cash Transfers, Household Risk and HIV Prevention in Kenya
    Sudhanshu Handa; Fiscal Year: 2013
    ..and how time preferences, subjective risk assessment and risk aversion influence the propensity to engage in choice behavior with long time horizons such as savings, human capital investment and risky sexual activity...
  18. Adolescent Alcohol Exposure and Risky Decision-Making
    Nicholas Nasrallah; Fiscal Year: 2009
    ..The long-range goal of this proposal is to assess the effects of voluntary adolescent alcohol intake on choice behavior in a rodent model...
  19. Neural representation of reward in frontal cortex
    Jonathan D Wallis; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The neural mechanisms underlying choice behavior are important for understanding addiction, a characteristic of which is a failure to exert control over choices...
  20. Impaired Insight and Drug-Seeking Behavior in Cocaine Addiction: an fMRI Study
    Scott J Moeller; Fiscal Year: 2012
    ..This fMRI insight-into-errors data will then be used to predict subsequent cocaine-related choice behavior. This latter study component will be accomplished through the use of the Preference for Image Viewing, ..
  21. Consumer Assessment of Healthcare Providers and Systems CAHPS IV
    Paul D Cleary; Fiscal Year: 2013
    ..consumer survey design, report development, experimental assessment of consumer perceptions and medical care choice behavior, quality improvement, evaluation research, and community-based dissemination methods from the School of ..
  22. Behavioral Economics in MR/DD and Behavior Disorders
    ISER DELEON; Fiscal Year: 2013
    ..In the initial budget period, we conducted investigations that demonstrated that a) the choice behavior of children with IDD and behavior disorders is systematically sensitive to behavioral economic manipulations ..
  23. Cognitive Function in Alcohol Dependence and Protracted Withdrawal
    Loren H Parsons; Fiscal Year: 2013
    ..Impulsive choice behavior will be indexed using the Delay Discount Test, and cognitive flexibility will be assessed using an operant ..
  24. Contribution of dopamine to risk attitude across the lifespan
    Paul E M Phillips; Fiscal Year: 2013
    ..valuation and reinforcement learning provides a powerful tool for insight into the underlying substrates of choice behavior across the lifespan...
  25. CELL TYPES IN ORBITOFRONTAL CORTEX AND THEIR CAUSAL INFLUENCE ON ECONOMIC CHOICE
    Camillo Padoa-Schioppa; Fiscal Year: 2012
    ..Demonstrating a causal relationship between the encoding of value in OFC and choice behavior would represent an important breakthrough...
  26. Aging and Metacognition in Strategic Skill Acquisition
    Christopher Hertzog; Fiscal Year: 2009
    ..of these effects by extending them to other skill acquisition tasks, and evaluating consistent conservative choice behavior across a variety of task domains, and (4) conduct extensive individual differences studies that evaluate the ..
  27. Neural mechanism of preference formation during risky decisions
    Timothy J Pleskac; Fiscal Year: 2013
    ..of risky decision making and establish potentially important links between process-level measures of choice behavior and drug use, thereby setting the stage for a greater understanding of the neural and computational basis of ..
  28. Emotions and Choice: Mechanisms of Behavior Change
    ELIZABETH ANYA PHELPS; Fiscal Year: 2013
    ..emotional response known to impact health decisions, namely stress, alters both the specific decision variables and the effectiveness of the proposed techniques used to alter emotional responses and choice behavior.
  29. Impact of cocaine on the Actor/Critic circuit
    Matthew R Roesch; Fiscal Year: 2013
    ..has been shown to be abnormal in addiction, which makes sense, considering that addicts cannot optimize choice behavior in the face of changing consequences...
  30. Effects of DA D1 and D2 agonists on reward sensitivity
    Valeri Farmer Dougan; Fiscal Year: 2004
    ..proposed research is to investigate the role of dopamine (DA), and in particular DA D1 and D2 receptors, in choice behavior using a matching law model of choice...
  31. Temporal Dynamics
    JOHN STADDON; Fiscal Year: 2006
    ..Experimental research on free-operant choice behavior over the past 40 years is based on the idea that response rate or choice probability is determined by the ..
  32. The Neuronal Mechanisms Underlying Choice Behavior in the Frontal Lobe
    Steve Kennerley; Fiscal Year: 2009
    ..A recent model of decision-making has proposed that the orbitofrontal cortex (OFC) contributes to choice behavior by integrating all of the variables necessary to make a decision...
  33. Long-Term Cocaine Effects on Impulsive Choice and Orbitofrontal Cortex Activity
    NICHOLAS SIMON; Fiscal Year: 2009
    ..activity in the orbitofrontal cortex, and whether such neurobiological alterations are related to impulsive choice behavior in the delay discounting task...
  34. Development of a Novel Trial-by-Trial Consequence Human Delay Discounting Task
    Matthew Johnson; Fiscal Year: 2009
    ..of contingent consequences, rather than direct operant experience within the session that can influence choice behavior on subsequent trials...
  35. The neurobiology of human reinforcement learning throughout the lifespan
    ROBB RUTLEDGE; Fiscal Year: 2009
    ..Our specific aims are as follows: 1) To determine to what extent the choice behavior of young and elderly subjects matches the predictions of animal reinforcement learning models in a task with ..
  36. Neural Systems of Learning and Memory in Addiction
    Daphna Shohamy; Fiscal Year: 2009
    ..The central aim is to understand how to modulate the contribution of these two learning systems to choice behavior, at both the neural and behavioral levels...
  37. MODELS FOR LEARNING, MEMORY, AND INFERENCE
    JOHN STADDON; Fiscal Year: 2001
    ..learning (operant and classical conditioning) and, if so, how? Is rate-sensitivity involved in recurrent choice behavior. Many experimental results suggest that it is, but no existing models take account of it...
  38. FACTORS INFLUENCING RESPONSE STRENGTH
    Edmund Fantino; Fiscal Year: 1990
    The proposed experiments investigate choice behavior. One group of experiments assesses the PI's delay-reduction hypothesis of choice and conditioned reinforcement which states that the effectiveness of a stimulus as a conditioned ..
  39. Neurobiological Bases of Economic Choice Behavior
    Camillo Padoa Schioppa; Fiscal Year: 2007
    ..b>Choice behavior is a traditional focus in economics and psychology...
  40. Health Plan Choice: Implications for Consumers & Purcha
    MARY BUNDORF; Fiscal Year: 2005
    ..To analyze individual choice among health plans, the candidate will conduct econometric studies of individual choice behavior, focusing on the elderly and near-elderly...
  41. NOVEL ANIMAL MODEL FOR TREATING COCAINE CRAVING
    RICHARD FOLTIN; Fiscal Year: 2000
    ..By measuring location preference, choice behavior, and responding, we believe that information about motivational processes relevant to human drug seeking will ..
  42. The Role of the Posterior Cingulate Cortex in Reward-Guided Decision-Making
    Benjamin Hayden; Fiscal Year: 2009
    ..aspects of risky decision-making are subserved by PCC neurons by examining the effect of microstimulation on choice behavior in the visual gambling task...
  43. Reference-dose method and cocaine-conditioned choice
    RICK BEVINS; Fiscal Year: 2006
    ..The following Aims will be used to obtain this goal. Specific Aim 1 will assess the change in choice behavior that occurs when varying doses of cocaine paired with one environment (e.g., 0.1, 0.3, 0.45, 0.6, 0.9, or 1...
  44. INFLUENCE OF MEMORY STRUCTURES ON IMPRESSION CHANGE
    John Lingle; Fiscal Year: 1980
    ..model of memory-based impression judgements is presented capable of accounting for subjects' choice behavior. Five studies are proposed that would make it possible to extend the model to account for impression change ..
  45. Smoking Versus Alternative Reinforcers in Adolescents
    Suzanne Colby; Fiscal Year: 2007
    ..probabilistic) affects smoking choice behavior, and whether this behavior is moderated by baseline risk-taking level; and 3) to investigate whether ..
  46. NEUROECONOMICS OF AGE RELATED CHANGES IN COGNITIVE CONTROL
    TODD BRAVER; Fiscal Year: 2009
    ..The findings of these studies promise to provide critical new data regarding economic choice behavior in older adults, and the relationship of such behavior to age-related changes in the neural substrates of ..
  47. SNRP PROJECT AT MEHARRY MEDICAL COLLEGE
    HUBERT RUCKER; Fiscal Year: 2009
    ..data, and communicating these findings in oral and written form to achieve the individual success of these investigators and to strengthen the portfolio of bench to bedside neuroscience research at MMC and with its Alliance partner, VUMC ..
  48. THE DEVELOPMENT OF HIERARCHICAL CATEGORY STRUCTURE
    ELIZABETH SHIPLEY; Fiscal Year: 1980
    ..In addition, choice behavior when obvious (for the adult) exemplars are not presented is being examined for basic level and superordinate ..
  49. CHOICE CRITERION EFFECTS IN SPATIAL MEMORY PERFORMANCE
    Michael Brown; Fiscal Year: 1992
    ..The present experiments are designed to explore psychological process other than working memory that affect choice behavior in this maze...
  50. MOLECULAR ANALYSIS OF CHOICE BEHAVIOR
    CHARLES SHIMP; Fiscal Year: 1980
    ....
  51. Individual Differences in Choice Study Predict Drug Use
    GENE HEYMAN; Fiscal Year: 2004
    ..The first set of studies tested drug clinic patients. Choice behavior was correlated with drug use history...
  52. MOLECULAR VARIABLES AFFECTING CHOICE BEHAVIOR
    JAMES MAZUR; Fiscal Year: 2009
    ..DESCRIPTION (provided by applicant): This research will examine how "molecular" (small-scale) variables affect choice behavior. One line of research will examine how individuals choose between a small immediate reinforcer and larger ..
  53. PREFERENCE AND SELECTIVE ASSOCIATIONS
    STANLEY WEISS; Fiscal Year: 1991
    ..The stimulus-preference interaction model parsimoniously relates these selective associations to fundamental psychological processes responsible for choice behavior and conditioned preference.
  54. Neuropharmacology of Tramadol: Clinical Efficacy and Abuse Potential
    WILLIAM WALTON STOOPS; Fiscal Year: 2010
    ..Developing analgesics with reduced abuse potential may reduce the prevalence of prescription opioid misuse and subsequent opioid use disorders. ..
  55. Choices in time and neural activity in parietal cortex
    KENWAY LOUIE; Fiscal Year: 2008
    ..Decision studies to date, however, have ignored information about time, a crucial element of choice behavior: real world decisions occur between choices with different outcomes at different times...
  56. ALCOHOL APPETITE--A NUTRIENT CONDITIONING ANALYSIS
    Karen Ackroff; Fiscal Year: 2001
    ..It will advance our basic knowledge of the psychobiology of alcohol appetite and may provide practical benefits for controlling alcohol consumption in humans. ..
  57. Dopamine D2 and Adenosine A2A roles:Tremulous Movements
    John Salamone; Fiscal Year: 2007
    ..abstract_text> ..
  58. MOTOR EFFECTS OF ATYPICAL ANTIPSYCHOTICS
    John Salamone; Fiscal Year: 2003
    ..Taken together, the results of these experiments will help to identify the pharmacological characteristics and brain circuits that underlie the motor effects of clozapine. ..
  59. Neuropharmacology of Learned Food Preferences
    Anthony Sclafani; Fiscal Year: 2009
    ..It will advance our understanding of the basic mechanisms involved in the development of food preferences and may provide insights into the clinical treatment of overeating and obesity. ..
  60. Effort-related Functions of Nucleus Accumbens Adenosine A2A Receptors
    John D Salamone; Fiscal Year: 2010
    ....
  61. BEHAVIORAL EFFECTS OF NIGRAL D1 ANTAGONISM
    John Salamone; Fiscal Year: 2001
    ....