sensory thresholds

Summary

Summary: The minimum amount of stimulus energy necessary to elicit a sensory response.

Top Publications

  1. ncbi The psychometric function: I. Fitting, sampling, and goodness of fit
    F A Wichmann
    University of Oxford, England
    Percept Psychophys 63:1293-313. 2001
  2. ncbi Predicting odor pleasantness from odorant structure: pleasantness as a reflection of the physical world
    Rehan M Khan
    Helen Wills Neuroscience Institute and Department of Psychology, University of California, Berkeley, Berkeley, California 94720, USA
    J Neurosci 27:10015-23. 2007
  3. ncbi Normative data for the "Sniffin' Sticks" including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects
    T Hummel
    Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Fetscherstrasse 74, 01307, Dresden, Germany
    Eur Arch Otorhinolaryngol 264:237-43. 2007
  4. ncbi Stochastic resonance and sensory information processing: a tutorial and review of application
    Frank Moss
    Center for Neurodynamics, University of Missouri at St Louis, St Louis, MO, USA
    Clin Neurophysiol 115:267-81. 2004
  5. ncbi Bayesian adaptive estimation of psychometric slope and threshold
    L L Kontsevich
    Smith Kettlewell Eye Research Institute, San Francisco CA 94115, USA
    Vision Res 39:2729-37. 1999
  6. ncbi Tactile hyperacuity thresholds correlate with finger maps in primary somatosensory cortex (S1)
    Robert O Duncan
    Hamilton Glaucoma Center, University of California, San Diego, La Jolla, CA 92093 0946, USA
    Cereb Cortex 17:2878-91. 2007
  7. ncbi Vestibular thresholds for yaw rotation about an earth-vertical axis as a function of frequency
    Luzia Grabherr
    Department of Psychology, University of Lausanne, Bâtiment Anthropole, 1015 Lausanne, Switzerland
    Exp Brain Res 186:677-81. 2008
  8. ncbi Quantitative measurement of interocular suppression in children with amblyopia
    Sathyasri Narasimhan
    University of British Columbia, Department of Ophthalmology and Visual Sciences, Vancouver, BC, Canada
    Vision Res 66:1-10. 2012
  9. pmc Sex differences and reproductive hormone influences on human odor perception
    Richard L Doty
    Smell and Taste Center, University of Pennsylvania School of Medicine, Philadelphia PA 19104, USA
    Physiol Behav 97:213-28. 2009
  10. ncbi Level and mechanisms of perceptual learning: learning first-order luminance and second-order texture objects
    Barbara Anne Dosher
    Memory, Attention, and Perception MAP Laboratory, Department of Cognitive Sciences, Institute of Mathematical Behavioral Sciences, University of California, Irvine, 92697 5100, USA
    Vision Res 46:1996-2007. 2006

Research Grants

  1. ELECTROTACTILE DISPLAY OF COMPUTER GRAPHICS FOR BLIND
    KURT KACZMAREK; Fiscal Year: 2001
  2. A psychological study of vibrotactile temporal summation
    GEORGE GESCHEIDER; Fiscal Year: 2006
  3. Mechanisms of Spontaneous Neuropathic Pain
    Frank Porreca; Fiscal Year: 2013
  4. Posture and Orientation in Older Adults and Post-Stroke
    EMILY KESHNER; Fiscal Year: 2009
  5. Sleep in Cetaceans
    Jerome Siegel; Fiscal Year: 2006
  6. NEUROPHYSIOLOGICAL CHANGES IN ADULTS EXPOSED TO SOLVENTS
    Allene Scott; Fiscal Year: 1999
  7. ANTIBODY NOCICEPTOR SENSITIZATION & ALLOYDNIA
    Linda Sorkin; Fiscal Year: 2000
  8. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Enrique Cometto Muniz; Fiscal Year: 2010
  9. Molecular Boundaries For Trigeminal Chemosensory Impact
    J Cometto Muniz; Fiscal Year: 2006
  10. Temporal Integration in Nasal Lateralization
    Paul Wise; Fiscal Year: 2007

Detail Information

Publications271 found, 100 shown here

  1. ncbi The psychometric function: I. Fitting, sampling, and goodness of fit
    F A Wichmann
    University of Oxford, England
    Percept Psychophys 63:1293-313. 2001
    ..We have made available the software to implement our methods...
  2. ncbi Predicting odor pleasantness from odorant structure: pleasantness as a reflection of the physical world
    Rehan M Khan
    Helen Wills Neuroscience Institute and Department of Psychology, University of California, Berkeley, Berkeley, California 94720, USA
    J Neurosci 27:10015-23. 2007
    ..However, our findings suggest that olfactory pleasantness is also partially innate, corresponding to a natural axis of maximal discriminability among biologically relevant molecules...
  3. ncbi Normative data for the "Sniffin' Sticks" including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects
    T Hummel
    Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Fetscherstrasse 74, 01307, Dresden, Germany
    Eur Arch Otorhinolaryngol 264:237-43. 2007
    ..Further, the present data suggest specific changes of individual olfactory functions in relation to age, with odor thresholds declining most dramatically compared to odor discrimination and odor identification...
  4. ncbi Stochastic resonance and sensory information processing: a tutorial and review of application
    Frank Moss
    Center for Neurodynamics, University of Missouri at St Louis, St Louis, MO, USA
    Clin Neurophysiol 115:267-81. 2004
    ..To review the stochastic resonance phenomena observed in sensory systems and to describe how a random process ('noise') added to a subthreshold stimulus can enhance sensory information processing and perception...
  5. ncbi Bayesian adaptive estimation of psychometric slope and threshold
    L L Kontsevich
    Smith Kettlewell Eye Research Institute, San Francisco CA 94115, USA
    Vision Res 39:2729-37. 1999
    ..Threshold estimation within 2 dB (23%) precision requires less than 30 trials for a typical 2AFC detection task. To get the slope estimate with the same precision takes about 300 trials...
  6. ncbi Tactile hyperacuity thresholds correlate with finger maps in primary somatosensory cortex (S1)
    Robert O Duncan
    Hamilton Glaucoma Center, University of California, San Diego, La Jolla, CA 92093 0946, USA
    Cereb Cortex 17:2878-91. 2007
    ..These results suggest that tactile hyperacuity is largely determined by the cortical representation of the fingers in S1...
  7. ncbi Vestibular thresholds for yaw rotation about an earth-vertical axis as a function of frequency
    Luzia Grabherr
    Department of Psychology, University of Lausanne, Bâtiment Anthropole, 1015 Lausanne, Switzerland
    Exp Brain Res 186:677-81. 2008
    ..71 deg s(-1) and a cut-off frequency of 0.23 Hz, which corresponds to a time constant of approximately 0.70 s. These findings provide no evidence for an influence of velocity storage on perceptual yaw rotation thresholds...
  8. ncbi Quantitative measurement of interocular suppression in children with amblyopia
    Sathyasri Narasimhan
    University of British Columbia, Department of Ophthalmology and Visual Sciences, Vancouver, BC, Canada
    Vision Res 66:1-10. 2012
    ..Contrast interference thresholds were significantly lower in the strabismic group than in the anisometropic and control group. Our results suggest that interocular suppression is stronger in strabismic than in anisometropic amblyopia...
  9. pmc Sex differences and reproductive hormone influences on human odor perception
    Richard L Doty
    Smell and Taste Center, University of Pennsylvania School of Medicine, Philadelphia PA 19104, USA
    Physiol Behav 97:213-28. 2009
    ..We conclude that the relationship between reproductive hormones and human olfactory function is complex and that simple associations between circulating levels of gonadal hormones and measures of olfactory function are rarely present...
  10. ncbi Level and mechanisms of perceptual learning: learning first-order luminance and second-order texture objects
    Barbara Anne Dosher
    Memory, Attention, and Perception MAP Laboratory, Department of Cognitive Sciences, Institute of Mathematical Behavioral Sciences, University of California, Irvine, 92697 5100, USA
    Vision Res 46:1996-2007. 2006
    ..It serves to amplify the stimulus relative to limiting internal noise for intrinsically noisy representations of second-order stimuli...
  11. ncbi The challenges natural images pose for visual adaptation
    Fred Rieke
    Howard Hughes Medical Institute, Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA
    Neuron 64:605-16. 2009
    ..Multiple adaptational mechanisms in different locations within the retina act in concert to accomplish this task, with lighting conditions dictating which mechanisms dominate...
  12. ncbi Binocular contrast vision at and above threshold
    Tim S Meese
    School of Life and Health Sciences, Aston University, Birmingham, UK
    J Vis 6:1224-43. 2006
    ..A review of evidence from elsewhere leads us to favor the two-stage model...
  13. ncbi Blindness enhances tactile acuity and haptic 3-D shape discrimination
    J Farley Norman
    Department of Psychology, Western Kentucky University, 1906 College Heights Blvd 21030, Bowling Green, KY 42101 1030, USA
    Atten Percept Psychophys 73:2323-31. 2011
    ..The results of the present study demonstrate that blindness does lead to an enhancement of tactile abilities, but they also suggest that early visual experience may play a role in facilitating haptic 3-D shape discrimination...
  14. ncbi Clinical significance of results from olfactory testing
    Volker Gudziol
    Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany
    Laryngoscope 116:1858-63. 2006
    ..Although widely used in healthy subjects and patients with olfactory loss, the significance of changes of scores from validated olfactory tests is unknown...
  15. ncbi Chromatic discrimination losses in multiple sclerosis patients with and without optic neuritis using the Cambridge Colour Test
    Ana Laura de Araújo Moura
    Depto Psicologia Experimental, Instituto de Psicologia, Universidade de Sao Paulo, Sao Paulo, Brasil
    Vis Neurosci 25:463-8. 2008
    ..The CCT is a useful tool to help characterize vision losses in MS, and the relationship between these losses and degree of optic nerve involvement...
  16. ncbi Cross-orientation summation in texture segregation
    Isamu Motoyoshi
    Human and Information Science Laboratory, NTT Communication Science Laboratories, NTT Corporation, 3 1 Morinosato Wakamiya, Atsugi, Kanagawa, 243 0198, Japan
    Vision Res 44:2567-76. 2004
    ....
  17. ncbi Effects of repetitive electrical stimulation to treat sensory loss in persons poststroke
    Patricia S Smith
    Department of Physical Therapy, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Arch Phys Med Rehabil 90:2108-11. 2009
    ..Smith PS, Dinse HR, Kalisch T, Johnson M, Walker-Batson D. Effects of repetitive electrical stimulation to treat sensory loss in persons poststroke...
  18. pmc Learning letter identification in peripheral vision
    Susana T L Chung
    College of Optometry and Center for Neuro Engineering and Cognitive Science, University of Houston, 505 J Davis Armistead Bldg, Houston, TX 77204 2020, USA
    Vision Res 45:1399-412. 2005
    ..Results from both the PTM analysis and the double-pass experiment imply that the stimulus-dependent component of the internal noise does not change with learning...
  19. ncbi Expectations change the signatures and timing of electrophysiological correlates of perceptual awareness
    Lucia Melloni
    Department of Neurophysiology, Goethe University, D 60528 Frankfurt am Main, Germany
    J Neurosci 31:1386-96. 2011
    ..These findings indicate that the latency of the neuronal correlates of access to consciousness depend on whether access is driven by stimulus saliency or by a combination of expectations and sensory evidence...
  20. ncbi Sensitivity to contrast modulation depends on carrier spatial frequency and orientation
    S C Dakin
    McGill Vision Research, Department of Ophthalmology, Montreal, Que, Canada
    Vision Res 40:311-29. 2000
    ..A final experiment measured envelope detection in the presence of noise masks. Results indicate that orientationally and spatially-band pass filtering precedes the detection of second-order structure...
  21. ncbi Differential aging of motion processing mechanisms: evidence against general perceptual decline
    Jutta Billino
    Department of Experimental Psychology, Justus Liebig University, Otto Behaghel Str 10F, D 35394 Giessen, Germany
    Vision Res 48:1254-61. 2008
    ..We suggest that differential age effects on the perception of specific motion types might indicate that specialized neuronal processing mechanisms differ in their vulnerability to physiological changes during aging...
  22. ncbi Noise-enhanced vibrotactile sensitivity in older adults, patients with stroke, and patients with diabetic neuropathy
    Wen Liu
    Center for BioDynamics and Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Arch Phys Med Rehabil 83:171-6. 2002
    ..To test the hypothesis that vibrotactile detection thresholds in older adults, patients with stroke, and patients with diabetic neuropathy can be significantly reduced with the introduction of mechanical noise...
  23. ncbi Pseudoradicular and radicular low-back pain--a disease continuum rather than different entities? Answers from quantitative sensory testing
    Rainer Freynhagen
    Department of Anesthesiology, Heinrich Heine University of Dusseldorf, Dusseldorf, Germany
    Pain 135:65-74. 2008
    ..The spatial incongruence of pain and sensory loss in pseudoradicular pain, however, may also indicate that the two are not causally related...
  24. ncbi Detection of small-fiber neuropathy by sudomotor testing
    Victoria A Low
    Department of Neurology, Mayo Clinic, Guggenheim 811, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 34:57-61. 2006
    ..Sudomotor examination is thus a highly sensitive detection tool in DSFN. Autonomic involvement is mainly distal, and additionally may involve adrenergic and the long cardiovagal fibers...
  25. ncbi A cognitive signal for the proactive timing of action in macaque LIP
    Gaby Maimon
    Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Neurosci 9:948-55. 2006
    ..This activity differs from sensory- and motor-related activity recorded in nearby cortical areas and could provide an internal trigger for action when abrupt external triggers in the visual input are unavailable...
  26. ncbi Attention enhances contrast sensitivity at cued and impairs it at uncued locations
    Franco Pestilli
    Department of Psychology, New York University, 6 Washington Place, 8th Fl, New York, NY 10003 6634, USA
    Vision Res 45:1867-75. 2005
    ..These results are consistent with the idea of limited resources, and indicate that transient attention helps control the expenditure of cortical computation...
  27. ncbi Differential activation in somatosensory cortex for different discrimination tasks
    C Braun
    Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, D 72074 Tubingen, Germany
    J Neurosci 20:446-50. 2000
    ....
  28. ncbi Timing of target discrimination in human frontal eye fields
    Jacinta O'Shea
    Department of Experimental Psychology, University of Oxford, UK
    J Cogn Neurosci 16:1060-7. 2004
    ..Our findings demonstrate a crucial early role for human FEF in visual target discrimination that is independent of saccade programming...
  29. ncbi TRPM8 is required for cold sensation in mice
    Ajay Dhaka
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Neuron 54:371-8. 2007
    ..Therefore, depending on context, TRPM8 contributes to sensing unpleasant cold stimuli or mediating the effects of cold analgesia...
  30. ncbi Adaptive coincidence detection and dynamic gain control in visual cortical neurons in vivo
    Rony Azouz
    Center for Computational Biology and Department of Cell Biology and Neuroscience, Montana State University, Bozeman, MT 59717, USA
    Neuron 37:513-23. 2003
    ..These findings suggest that under high-input conditions the spike-generating mechanism adaptively enhances the sensitivity to synchronous inputs while simultaneously decreasing the sensitivity to temporally uncorrelated inputs...
  31. ncbi Tactile spatial resolution in blind braille readers
    R W Van Boven
    Department of Neurology, Northwestern University Medical School, Chicago, IL, USA
    Neurology 54:2230-6. 2000
    ..To determine if blind people have heightened tactile spatial acuity...
  32. ncbi Measuring, estimating, and understanding the psychometric function: a commentary
    S A Klein
    School of Optometry, University of California, Berkeley 94720 2020, USA
    Percept Psychophys 63:1421-55. 2001
    ....
  33. pmc Differential effects of synchronous and asynchronous multifinger coactivation on human tactile performance
    Tobias Kalisch
    Department of Theoretical Biology, Institute for Neuroinformatics, Ruhr University Bochum, D 44780 Bochum Germany
    BMC Neurosci 8:58. 2007
    ..Here we investigated the effect of different types of multifinger CA on the tactile performance of each finger of the right hand...
  34. ncbi Impaired tactile acuity in old age is accompanied by enlarged hand representations in somatosensory cortex
    Tobias Kalisch
    Department of Theoretical Biology, Institute for Neuroinformatics, Ruhr University Bochum, Bochum, Germany
    Cereb Cortex 19:1530-8. 2009
    ..Whereas learning-related map changes are assumed to result from specific strengthening of synaptic connections, we suggest that the age-related map changes are related to the reduction of intracortical inhibition developing with age...
  35. ncbi When is scene identification just texture recognition?
    Laura Walker Renninger
    The Smith Kettlewell Eye Research Institute, 2318 Fillmore Street, San Francisco, CA 94115, USA
    Vision Res 44:2301-11. 2004
    ..The texture analysis leads to similar identifications and confusions as subjects with limited processing time. We conclude that early scene identification can be explained with a simple texture recognition model...
  36. ncbi Orientation discrimination in 5-year-olds and adults tested with luminance-modulated and contrast-modulated gratings
    Terri L Lewis
    Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada
    J Vis 7:9. 2007
    ..Together, the findings suggest that orientation discrimination is slow to develop and worse for second-order than first-order patterns in both children and adults...
  37. ncbi Seeing slow and seeing fast: two limits on perception
    Alex O Holcombe
    School of Psychology, University of Sydney, Brennan MacCallum Bldg A18, Sydney, NSW 2006, Australia
    Trends Cogn Sci 13:216-21. 2009
    ..These temporally coarse percepts might all be mediated by high-level processes. Working at very different timescales, the two groups of mechanisms collaborate to create our unified visual experience...
  38. ncbi Spatial four-alternative forced-choice method is the preferred psychophysical method for naïve observers
    Frank Jäkel
    Max Planck Institute for Biological Cybernetics, Tubingen, Germany
    J Vis 6:1307-22. 2006
    ....
  39. pmc Olfaction and taste processing in autism
    Loisa Bennetto
    Department of Clinical and Social Sciences in Psychology, University of Rochester, Rochester, New York 14627, USA
    Biol Psychiatry 62:1015-21. 2007
    ..We examined olfactory and taste functioning in individuals with autism to characterize chemosensory processing and test competing hypotheses about underlying brainstem versus cortical abnormalities...
  40. ncbi Tactile sensitivity of children: effects of frequency, masking, and the non-Pacinian I psychophysical channel
    Burak Güçlü
    Biomedical Engineering Institute, Bogazici University, Istanbul 34342, Turkey
    J Exp Child Psychol 98:113-30. 2007
    ..These findings contradict the hypothesis that there is gradual loss of tactile sensitivity starting from childhood to early adulthood. The loss of sensitivity due to aging probably is more abrupt and occurs at a later age...
  41. ncbi Visual experience can substantially alter critical flicker fusion thresholds
    Aaron R Seitz
    Department of Neurobiology, Harvard Medical School, 220 Longwood Ave, Boston, MA 02115, USA
    Hum Psychopharmacol 20:55-60. 2005
    ..The results show that the perceptual experience of subjects can dramatically alter the CFF thresholds and should be an important consideration in the control of studies employing the CFF as a measure...
  42. ncbi Cultural adaptation of an olfactory identification test: the Greek version of Sniffin' Sticks
    I Konstantinidis
    2nd Otorhinolaryngology Department, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece
    Rhinology 46:292-6. 2008
    ..Sniffin sticks battery is a well-validated olfactory test in German speaking population. However adaptation of this test in the cultural background of a country is mandatory before use...
  43. ncbi Reproducibility and influence of test modality order on thermal perception and thermal pain thresholds in quantitative sensory testing
    Victoria Heldestad
    Division of Clinical Neurophysiology, Umea University, SE 901 85 Umea, Sweden
    Clin Neurophysiol 121:1878-85. 2010
    ....
  44. pmc Human discrimination of rotational velocities
    Robert M Mallery
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Exp Brain Res 204:11-20. 2010
    ..Quantifying this relationship may help elucidate the role of higher-level processes in maintaining balance and provide information to diagnose and guide therapy of patients with central causes for imbalance...
  45. pmc Efficient integration across spatial frequencies for letter identification in foveal and peripheral vision
    Anirvan S Nandy
    Department of Psychology, University of Southern California, Los Angeles, CA 90089 1061, USA
    J Vis 8:3.1-20. 2008
    ..Our findings suggest that deficiency in feature integration found in peripheral vision is not across spatial frequencies...
  46. ncbi Determinants for nasal trigeminal detection of volatile organic compounds
    J Enrique Cometto-Muniz
    Chemosensory Perception Laboratory, Department of Surgery, University of California, San Diego, 9500 Gilman Drive, Mail Code 0957, La Jolla, CA 92093 0957, USA
    Chem Senses 30:627-42. 2005
    ....
  47. ncbi Second-order spatial frequency and orientation channels in human vision
    Dave Ellemberg
    Universite de Montreal, Département de Kinésiologie, Canada
    Vision Res 46:2798-803. 2006
    ..This is consistent with a filter-rectify-filter scheme for second-order in which the second stage of filtering is at lower spatial frequencies...
  48. pmc Parafoveal color discrimination: a chromaticity locus of enhanced discrimination
    Marina V Danilova
    Laboratory of Visual Physiology, I P Pavlov Institute of Physiology, St Petersburg, Russia
    J Vis 10:4.1-9. 2010
    ..This line of optimal discrimination is not aligned with either of the cardinal axes of color space: In a MacLeod-Boynton chromaticity diagram, it runs obliquely with negative slope...
  49. ncbi Clinical and physiological findings, and possible aetiological factors of rectal hyposensitivity
    M A Gladman
    Academic Department of Surgery and Gastrointestinal Physiology Unit, St Bartholomew s and the London School of Medicine and Dentistry, London, UK
    Br J Surg 90:860-6. 2003
    ..Rectal hyposensitivity (RH) relates to insensitivity of the rectum on anorectal physiological investigation and appears common in functional bowel disorders. The clinical significance of this physiological abnormality is unclear...
  50. pmc Specificity of perceptual learning increases with increased training
    Pamela E Jeter
    Memory, Attention and Perception Laboratory MAP, Department of Cognitive Sciences, University of California, Irvine, CA 92697, USA
    Vision Res 50:1928-40. 2010
    ..Brief training shows the best performance at the point of transfer. These results for orientation-location transfer have both theoretical and practical implications for understanding perceptual expertise...
  51. ncbi Olfaction in patients with mild cognitive impairment and Alzheimer's disease
    Jelena Djordjevic
    Montreal Neurological Institute, 3801 University Street, Department of Neurology and Neurosurgery, McGill University, Montreal, H3A 2B4, Quebec, Canada
    Neurobiol Aging 29:693-706. 2008
    ..High detection thresholds, together with impaired identification, may be useful as an early indicator of AD...
  52. ncbi The effect of flankers on three tasks in central, peripheral, and amblyopic vision
    Dennis M Levi
    School of Optometry and Helen Wills Neuroscience Institute, UC Berkeley, Berkeley, CA, USA
    J Vis 11:10. 2011
    ..On the other hand, in peripheral vision and strabismic amblyopia, the effects of flankers on orientation discrimination and to a lesser extent contrast discrimination cannot be explained by simple masking and are due to crowding...
  53. pmc Predicting direction detection thresholds for arbitrary translational acceleration profiles in the horizontal plane
    Florian Soyka
    Department of Human Perception, Cognition and Action, Max Planck Institute for Biological Cybernetics, Spemannstraße 38, 72076, Tubingen, Germany
    Exp Brain Res 209:95-107. 2011
    ..Our modeling approach represents an important advancement, because it allows for a more general and accurate description of perceptual thresholds for simple and complex translational motions...
  54. ncbi Bias in magnitude estimation following left hemisphere injury
    Adam J Woods
    Department of Neurobiology and Developmental Sciences, The University of Arkansas for Medical Sciences, United States
    Neuropsychologia 44:1406-12. 2006
    ..This is the first evidence, to our knowledge, that left hemisphere injury can bias magnitude estimation in a manner similar but not identical to that associated with right hemisphere injury...
  55. ncbi Orientation-sensitivity of face identity aftereffects
    Gillian Rhodes
    School of Psychology, The University of Western Australia, Australia
    Vision Res 49:2379-85. 2009
    ..With orientation varied within participants, the results were less clear. We suggest that adaptation of expert face-coding mechanisms can contribute to face identity aftereffects, although the effect may not be very robust...
  56. ncbi Olfactory functioning in schizophrenia: relationship to clinical, neuropsychological, and volumetric MRI measures
    Paul J Moberg
    Schizophrenia Research Center, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Clin Exp Neuropsychol 28:1444-61. 2006
    ....
  57. ncbi Exploration of small fibers for testing diabetic neuropathies
    Fawzia Cheliout-Heraut
    UFR Paris Ile de France, ouest, France
    Joint Bone Spine 72:412-5. 2005
    ..and unmyelinated fiber (C-fibers) lesions a quantitative method has been perfected: the study of the sensory thresholds (quantitative sensory testing: QST)...
  58. ncbi Detection, discrimination and integration of second-order orientation information in strabismic and anisometropic amblyopia
    Behzad Mansouri
    Department of Opthalmology, McGill Vision Research Unit, 687 Pine Avenue West, Rm H4 14, Montreal, Quebec, Canada H3A 1A1
    Vision Res 45:2449-60. 2005
    ..Orientation discrimination for an isolated second-order patch was comparable in normal and amblyopic eyes. We showed that pure integration of second-order patterns can be normal in amblyopia...
  59. ncbi The influence of mecamylamine on trigeminal and olfactory chemoreception of nicotine
    Norbert Thuerauf
    Sensory Research Unit, Department of Psychiatry, University of Erlangen Nuremberg, Bavaria, Germany
    Neuropsychopharmacology 31:450-61. 2006
    ....
  60. pmc Global contour processing in amblyopia
    Dennis M Levi
    School of Optometry and Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 2020, USA
    Vision Res 47:512-24. 2007
    ..The residual deficits reported here cannot be simply ascribed to reduced visibility or increased positional uncertainty, and we therefore conclude that these are genuine deficits in global contour segregation and integration...
  61. ncbi Symptom scoring systems to diagnose distal polyneuropathy in diabetes: the Diabetic Neuropathy Symptom score
    J W G Meijer
    Rehabilitation CentreTolbrug Jeroen Bosch Hospital, Den Bosch, The Netherlands
    Diabet Med 19:962-5. 2002
    ..We validated a new four-item Diabetic Neuropathy Symptom (DNS) score for diagnosing distal diabetic polyneuropathy...
  62. ncbi Single pulse and pulse train modulation of cutaneous electrical stimulation: a comparison of methods
    Esther M van der Heide
    Institute for Biomedical Technology BMTI, EEMCS, University of Twente, Enschede, The Netherlands
    J Clin Neurophysiol 26:54-60. 2009
    ..These findings demonstrate that SP and PT involve different ways of processing. The two methods result in different Numeric Rating Scale scores and EP components. Furthermore, PT stimulation is less dependent on stimulus location...
  63. ncbi Psychophysical evidence for two routes to suppression before binocular summation of signals in human vision
    D H Baker
    Life and Health Sciences, Aston University, Aston Street, Birmingham B47ET, UK
    Neuroscience 146:435-48. 2007
    ..The interocular route is a good candidate for the initial pathway involved in binocular rivalry and predicts that interocular cross-orientation suppression should be found in cortical cells with predominantly ipsiocular drive...
  64. ncbi Correlation between motor and phosphene thresholds: a transcranial magnetic stimulation study
    Choi Deblieck
    Ahmanson Lovelace Brain Mapping Center, UCLA, Los Angeles, California, USA
    Hum Brain Mapp 29:662-70. 2008
    ..They also provide a rationale for the use of easily obtained aMT to calibrate TMS intensities in brain mapping studies that employ TMS in cortical regions besides motor cortex...
  65. ncbi Cross-orientation transfer of adaptation for facial identity is asymmetric: a study using contrast-based recognition thresholds
    Xiaoyue M Guo
    Wellesley College, Wellesley, MA, USA
    Vision Res 49:2254-60. 2009
    ..While these results are consistent with the dual-mode hypothesis, they can also be accounted for by a single population of units of varying orientation selectivity...
  66. ncbi Motion perception in the ageing visual system: minimum motion, motion coherence, and speed discrimination thresholds
    Robert J Snowden
    School of Psychology, Cardiff University, Wales, UK
    Perception 35:9-24. 2006
    ..It is concluded that these hypotheses do not provide an adequate account of the data, and therefore that the losses occurring with age are complex and probably are a result of the loss of several types of cell...
  67. ncbi A novel face aftereffect based on recognition contrast thresholds
    Ipek Oruc
    Human Vision and Eye Movement Laboratory, Department of Medicine Neurology, University of British Columbia, Vancouver, BC, Canada
    Vision Res 50:1845-54. 2010
    ..The findings indicate greater complexity to adaptation, with facilitation, suppression, lateral inhibition of unadapted representations, and additional perceptual factors at long durations...
  68. pmc Aging and visual motion discrimination in normal adults and schizophrenia patients
    L Cinnamon Bidwell
    Department of Psychology, University of Colorado, Boulder, CO, USA
    Psychiatry Res 145:1-8. 2006
    ..A similar motion-discrimination deficit in schizophrenia patients and aging normal adults suggests that the mechanisms underlying motion processing in schizophrenia and normal aging may be associated...
  69. ncbi Electrophysiological correlates of figure-ground segregation directly reflect perceptual saliency
    Sirko Straube
    Department of Human Neurobiology, University of Bremen, Hochschulring 18, 28359 Bremen, Germany
    Vision Res 50:509-21. 2010
    ..We demonstrate that visual cues interact for a percept that is non-linearly related to the physical figure-ground properties...
  70. ncbi Orientation-selective adaptation and tilt after-effect from invisible patterns
    S He
    Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, Minnesota 55455, USA
    Nature 411:473-6. 2001
    ....
  71. ncbi Tactile spatial resolution measured manually: a validation study
    Yannick Bleyenheuft
    Unite de Readaptation et de medecine physique, Universite Catholique de Louvain, Brussels, Belgium
    Somatosens Mot Res 24:111-4. 2007
    ..This study highlights the inter-examiner reliability in the manual application of this test and validates this procedure...
  72. ncbi Cross-cultural application of the "Sniffin' Sticks" odor identification test
    Chih Hung Shu
    Department of Otolaryngology, Taipei Veterans General Hospital, National Yang Ming University School of Medicine Faculty of Medicine, Taipei, Taiwan
    Am J Rhinol 21:570-3. 2007
    ..The aim of this study was to investigate the applicability of the "Sniffin' Sticks" odor identification test in an area with a different culture compared with its place of origin...
  73. ncbi Feature detection and letter identification
    Denis G Pelli
    Institute for Sensory Research, Syracuse University, Syracuse, New York, NY 13210, USA
    Vision Res 46:4646-74. 2006
    ..This, and the surprisingly fixed ratio of detection and identification thresholds, indicate that identifying a letter is mediated by detection of about 7 visual features...
  74. ncbi Correlation between olfactory bulb volume and olfactory function
    D Buschhüter
    Department of Otorhinolaryngology, University of Dresden Medical School, Fetscherstrasse 74, 01307 Dresden, Germany
    Neuroimage 42:498-502. 2008
    ..In conclusion, the present data obtained from a relatively large group of subjects forms the basis for age-related normative values of OB volumes...
  75. pmc Identification of contrast-defined letters benefits from perceptual learning in adults with amblyopia
    Susana T L Chung
    College of Optometry and Center for Neuro Engineering and Cognitive Science, University of Houston, Houston, TX, USA
    Vision Res 46:3853-61. 2006
    ....
  76. ncbi Barrages of synaptic activity control the gain and sensitivity of cortical neurons
    Yousheng Shu
    Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Neurosci 23:10388-401. 2003
    ..These results indicate that rapid increases in neuronal responsiveness, as well as increases in spike timing precision, can be achieved through balanced barrages of excitatory and inhibitory synaptic activity...
  77. ncbi Perceptual adaptation helps us identify faces
    Gillian Rhodes
    School of Psychology, University of Western Australia, Perth, WA, Australia
    Vision Res 50:963-8. 2010
    ....
  78. pmc Diminutive digits discern delicate details: fingertip size and the sex difference in tactile spatial acuity
    Ryan M Peters
    Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, Ontario L8S 4K1, Canada
    J Neurosci 29:15756-61. 2009
    ..Thus, a man and a woman with fingers of equal size will, on average, enjoy equal tactile acuity. We further show that sweat pores, and presumably the Merkel receptors beneath them, are packed more densely in smaller fingers...
  79. ncbi Phosphene thresholds evoked with single and double TMS pulses
    Thomas Kammer
    Department of Psychiatry, University of Ulm, Ulm, Germany
    Clin Neurophysiol 121:376-9. 2010
    ..To evaluate the quantitative advantage of double pulses vs. single pulses in TMS phosphenes evoked from the occipital cortex...
  80. ncbi Tactile spatial acuity enhancement in blindness: evidence for experience-dependent mechanisms
    Michael Wong
    McMaster Integrative Neuroscience Discovery and Study, McMaster University, Hamilton, Ontario, L8S 4K1 Canada
    J Neurosci 31:7028-37. 2011
    ....
  81. ncbi An updated review of clinical olfaction
    Eric H Holbrook
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, Massachusetts 02114, USA
    Curr Opin Otolaryngol Head Neck Surg 14:23-8. 2006
    ..Disorders of the sense of smell can result through hundreds of different processes, but most commonly occur from upper-respiratory-tract infections, trauma, and chronic rhinosinusitis...
  82. ncbi Visual form-processing deficits in autism
    Janine V Spencer
    Centre for Cognition and Neuroimaging, Brunel University, Uxbridge, UK
    Perception 35:1047-55. 2006
    ..Children with autism showed a significant form-coherence deficit and a significant motion-coherence deficit, while the performance of the children with Asperger syndrome did not differ significantly from that of controls on either task...
  83. pmc Kv1.3 channel gene-targeted deletion produces "Super-Smeller Mice" with altered glomeruli, interacting scaffolding proteins, and biophysics
    D A Fadool
    Department of Biological Science, Programs in Neuroscience and Molecular Biophysics, The Florida State University, Tallahassee, FL 32306, USA
    Neuron 41:389-404. 2004
    ..3 plays a far more reaching role in signal transduction, development, and olfactory coding than that of the classically defined role of a potassium channel-to shape excitability by influencing membrane potential...
  84. ncbi Lower olfactory threshold during the ovulatory phase of the menstrual cycle
    Evelia Navarrete-Palacios
    Hospital Central Militar, Ciudad de Mexico, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, 04510, Mexico, D F, Mexico
    Biol Psychol 63:269-79. 2003
    ..Thresholds for all control groups were higher than for the cycling women during the ovulatory phase. The results confirm that olfactory threshold is related to phase of the menstrual cycle and thus possibly to hormonal state...
  85. ncbi Modulation of moving phosphene thresholds by transcranial direct current stimulation of V1 in human
    Andrea Antal
    Department of Clinical Neurophysiology, George August University of Göttingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Neuropsychologia 41:1802-7. 2003
    ..Our results show that the excitability shifts induced by V1 stimulation can modulate moving phosphene perception. tDCS elicits transient, but yet reversible effects, thus presenting a promising tool for neuroplasticity research...
  86. ncbi Comparison of the Goldmann-Weekers dark adaptometer and LKC Technologies Scotopic Sensitivity tester-1
    A Y Peters
    Retina Foundation of the Southwest, Dallas, TX, USA
    Doc Ophthalmol 101:1-9. 2000
    ..We conclude, therefore, that the SST-1 is a viable alternative to the Goldmann-Weekers for the screening of night-blinding retinal disorders...
  87. ncbi Oral irritant properties of menthol: sensitizing and desensitizing effects of repeated application and cross-desensitization to nicotine
    J M Dessirier
    Section of Neurobiology, Physiology and Behavior, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA
    Physiol Behav 73:25-36. 2001
    ..Repeated application of menthol at the same short ISI was then resumed, and resulted in a significant mean increase in irritant intensity consistent with stimulus-induced recovery (SIR)...
  88. ncbi Task precision at transfer determines specificity of perceptual learning
    Pamela E Jeter
    Memory Attention Perception MAP Laboratory, Department of Cognitive Sciences, UC Irvine, Irvine, CA 92697 5100, USA
    J Vis 9:1.1-13. 2009
    ..These results contribute to understanding generalization of practiced improvements that may be key to the development of expertise and for applications in remediation...
  89. ncbi Enhancement of visual perception by crossmodal visuo-auditory interaction
    Francesca Frassinetti
    Dipartimento di Psicologia, Universita degli Studi di Bologna, Italy
    Exp Brain Res 147:332-43. 2002
    ..An enhancement of the perceptual sensitivity (d') for luminance detection was found when the audiovisual stimuli followed a rather clear spatial and temporal rule, governing multisensory integration at the neuronal level...
  90. ncbi The effects of surround contrast on contrast thresholds, perceived contrast and contrast discrimination
    R J Snowden
    Vision Research Unit, School of Psychology, Cardiff University, UK
    Vision Res 38:1935-45. 1998
    ....
  91. ncbi Characterisation of paired-pulse transcranial magnetic stimulation conditions yielding intracortical inhibition or I-wave facilitation using a threshold-hunting paradigm
    F Awiszus
    Neuromuscular Research Group at the Department of Orthopaedics, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Exp Brain Res 129:317-24. 1999
    ..The subsequent second stimulus served as a "booster" for the ongoing intracortical I-wave activity, making it impossible to observe the intracortical inhibition evoked by the first stimulus...
  92. ncbi The influence of current direction on phosphene thresholds evoked by transcranial magnetic stimulation
    T Kammer
    Department of Neurobiology, Max Planck Institute for Biological Cybernetics, Spemannstrasse 38, D 72076, Tubingen, Germany
    Clin Neurophysiol 112:2015-21. 2001
    ..To quantify phosphene thresholds evoked by transcranial magnetic stimulation (TMS) in the occipital cortex as a function of induced current direction...
  93. ncbi Color vision impairment in type 2 diabetes assessed by the D-15d test and the Cambridge Colour Test
    Claudia Feitosa-Santana
    Department of Psychology, University of Chicago, Chicago, IL, USA
    Ophthalmic Physiol Opt 30:717-23. 2010
    ..Considering the advantages of the CCT test compared to the D-15d test, further studies should attempt to verify and/or improve the efficiency of the CCT test...
  94. ncbi Low-level integration of auditory and visual motion signals requires spatial co-localisation
    Georg F Meyer
    Centre for Cognitive Neuroscience, School of Psychology, University of Liverpool, Eleanor Rathbone Bldg, Bedford Street South, Liverpool, L69 7AZ, UK
    Exp Brain Res 166:538-47. 2005
    ..We also argue that facilitation is only seen if the signals contain all localisation cues that would be produced by physical objects...
  95. pmc Accuracy of monofilament testing to diagnose peripheral neuropathy: a systematic review
    Jacquelien Dros
    Department of Family Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Ann Fam Med 7:555-8. 2009
    ..We wanted to summarize evidence about the diagnostic accuracy of the 5.07/10-g monofilament test in peripheral neuropathy...
  96. ncbi High-resolution maps of real and illusory tactile activation in primary somatosensory cortex in individual monkeys with functional magnetic resonance imaging and optical imaging
    Li M Chen
    Institute of Imaging Science, Vanderbilt University, Nashville, Tennessee 37232, USA
    J Neurosci 27:9181-91. 2007
    ..quot; These data demonstrate that at high field, high-spatial-resolution topographic maps can be achieved using the positive BOLD signal, weakening previous notions regarding the spatial specificity of the positive BOLD signal...
  97. ncbi Grating orientation as a measure of tactile spatial acuity
    J C Craig
    Department of Psychology, Indiana University, Bloomington 47405, USA
    Somatosens Mot Res 16:197-206. 1999
    ..The results support the view that grating orientation is a valid measure of spatial acuity reflecting underlying neural, spatial mechanisms...
  98. pmc Aging and the haptic perception of 3D surface shape
    J Farley Norman
    Department of Psychology and Center for the Study of Lifespan Development, Western Kentucky University, Bowling Green, KY 42101 1030, USA
    Atten Percept Psychophys 73:908-18. 2011
    ..The results of the current study demonstrate that while older adults do possess reductions in tactile sensitivity and acuity, they nevertheless can effectively perceive 3D surface shape from haptic exploration...
  99. ncbi A standard model for foveal detection of spatial contrast
    Andrew B Watson
    NASA Ames Research Center, Moffett Field, CA 94035 1000, USA
    J Vis 5:717-40. 2005
    ..But the results also illustrate the limited power of even this large data set to distinguish among similar competing models. We identify one model as a possible standard, suitable for simple theoretical and applied predictions...
  100. pmc Improvement of sensorimotor functions in old age by passive sensory stimulation
    Tobias Kalisch
    Department of Theoretical Biology, Institute for Neuroinformatics, Ruhr University Bochum, Bochum, Germany
    Clin Interv Aging 3:673-90. 2008
    ..Further optimizing of the stimulation protocol can be assumed to strengthen both the range and durability of its efficacy...
  101. ncbi Aging and the perception of speed
    J Farley Norman
    Department of Psychology, Western Kentucky University, Bowling Green, KY 42101 3576, USA
    Perception 32:85-96. 2003
    ....

Research Grants63

  1. ELECTROTACTILE DISPLAY OF COMPUTER GRAPHICS FOR BLIND
    KURT KACZMAREK; Fiscal Year: 2001
    ..to electrotactile displays: sensory adaptation and post- stimulus percept evaluated by measurement of sensory thresholds and also be cross-modality intensity matching; (4) electrode configuration in order to maximize spatial ..
  2. A psychological study of vibrotactile temporal summation
    GEORGE GESCHEIDER; Fiscal Year: 2006
    ..In temporal summation, sensory thresholds decline as a function of the duration of the stimulus, and in spatial summation the threshold declines as ..
  3. Mechanisms of Spontaneous Neuropathic Pain
    Frank Porreca; Fiscal Year: 2013
    ..as a translational and validating feature of the experimental pain condition and modulation of enhanced sensory thresholds is commonly used to explore mechanisms relevant to potential therapy...
  4. Posture and Orientation in Older Adults and Post-Stroke
    EMILY KESHNER; Fiscal Year: 2009
    ..We hypothesize that elderly adults and individuals post-stroke have increased sensory thresholds to complex multimodal stimuli which produces a greater reliance on predictive or on visual inputs making it ..
  5. Sleep in Cetaceans
    Jerome Siegel; Fiscal Year: 2006
    ..stimuli of different modalities to dolphins and whales adapted to sleep in stretchers to determine if sensory thresholds are altered ipsilateral and contralateral to USWS...
  6. NEUROPHYSIOLOGICAL CHANGES IN ADULTS EXPOSED TO SOLVENTS
    Allene Scott; Fiscal Year: 1999
    ..proposed study are to: (1) determine if there is a significant difference between vibratory and/or thermal sensory thresholds in solvent exposed versus non-exposed subjects; (2) determine if there is a significant difference between Q-..
  7. ANTIBODY NOCICEPTOR SENSITIZATION & ALLOYDNIA
    Linda Sorkin; Fiscal Year: 2000
    ..Ongoing activity and sensory thresholds will be recorded for identified primary afferent fibers, concentrating on A and C fibers thought to transmit ..
  8. CHEMICAL SENSORY IRRITATION: CONTRAST WITH OLFACTION
    J Enrique Cometto Muniz; Fiscal Year: 2010
    ..The outcome will allow us to make inferences about the relative breadth of chemical tuning in human olfaction and chemesthesis. ..
  9. Molecular Boundaries For Trigeminal Chemosensory Impact
    J Cometto Muniz; Fiscal Year: 2006
    ..abstract_text> ..
  10. Temporal Integration in Nasal Lateralization
    Paul Wise; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  11. EFFECT OF FETAL EXPOSURE TO ALCOHOL ON AGING
    Byron Campbell; Fiscal Year: 1991
    ..of behavioral tasks designed to trace the emergence during development and the decline during senescence of simple motor and reflexive behaviors, sensory thresholds, sensory-motor integrity, attentional processes and autonomic reactivity.
  12. Information transfer through ganglion cells
    Barry Lee; Fiscal Year: 2010
    ..abstract_text> ..
  13. POSTMENOPAUSAL ESTROGEN INFLUENCES ON OLFACTION
    RICHARD DOTY; Fiscal Year: 2005
    ..Third, it would lead to testable hypotheses regarding the role of reproductive hormones, and their underlying mechanisms, in the maintenance of normal olfactory function. ..
  14. Female Hormones and Vision
    Alvin Eisner; Fiscal Year: 2006
    ..abstract_text> ..
  15. OLFACTION IN EPILEPSY
    RICHARD DOTY; Fiscal Year: 2004
    ..In addition to providing a better understanding of the influences of TLE and TLR on human olfactory function, this work may lead to the development of a simple and inexpensive non-invasive means for better establishing TLE seizure loci. ..
  16. OLFACTION IN MULTIPLE SCLEROSIS
    RICHARD DOTY; Fiscal Year: 2001
    ....
  17. OLFACTORY CODING
    Burton Slotnick; Fiscal Year: 2003
    ..Behavior tasks will use precision olfactometry. Anterograde transport of horseradish peroxidase will be used to assess connections between the olfactory epithelium and olfactory bulb in experimental rats. ..
  18. FUNCTIONS AND MECHANISMS OF PERCEPTUAL LEARNING
    Barbara Dosher; Fiscal Year: 2003
    ....
  19. OLFACTORY FUNCTION IN GENE-TARGETED MICE
    Burton Slotnick; Fiscal Year: 2002
    ..A final report of these studies will incorporate a detailed description of apparatus, methods protocol and files of raw data and summary statistics presented in database and spreadsheet format. ..
  20. VISUAL ADAPTATION LIMITS AND AGE-RELATED DISEASE
    Alvin Eisner; Fiscal Year: 2002
    ....
  21. TRANSMISSION OF INFORMATION IN THE VISUAL SYSTEM
    Denis G Pelli; Fiscal Year: 2010
    ..Thus techniques from cognition, perception, statistical learning theory, and physiology together will reveal what is computed where, in the brain, when an observer identifies an object. ..
  22. The Organization of Suppression in Human Visual Cortex
    Suzanne McKee; Fiscal Year: 2008
    ..The multidimensional experimental design allows isolation of neural mechanisms utilized by perception, working memory, memory encoding, and recall. [unreadable] [unreadable]..
  23. STEREOACUITY AND BINOCULAR CORRESPONDENCE
    Suzanne McKee; Fiscal Year: 2006
    ..These studies of normal observers will provide basic knowledge about normal stereopsis, a prerequisite for understanding abnormalities of the binocular system [unreadable] [unreadable]..
  24. Human Sensory Irritation From Volitile Organic Compounds
    William Cain; Fiscal Year: 2006
    ..F) The effect of inflammation upon chemesthetic sensitivity. G) Through measurement of the NMP, confirmation of the peripheral basis for a) temporal phenomena, b) differences in potency, and c) effects of inflammation. ..
  25. Visual Dysfunction in Retinal Degenerations
    Kenneth R Alexander; Fiscal Year: 2010
    ....
  26. Factors influencing the evolution of knee osteoarthritis
    Najia Shakoor; Fiscal Year: 2008
    ..abstract_text> ..
  27. Epidemiology and Mechanisms of Fecal Incontinence
    Adil Bharucha; Fiscal Year: 2005
    ..abstract_text> ..
  28. Objective Assessment of Suppression in Amblyopia
    Suzanne McKee; Fiscal Year: 2003
    ..The proposed test could assist with the diagnosis of amblyopia in infancy, as well as in monitoring progress during treatment, thereby improving the chance of a favorable outcome. ..
  29. Higher order mechanisms in color discrimination
    ALLEN NAGY; Fiscal Year: 2003
    ..abstract_text> ..
  30. ANORECTAL MANIFESTATIONS OF FEMALE PELVIC FLOOR DISORDER
    Adil Bharucha; Fiscal Year: 2002
    ..abstract_text> ..
  31. 4th International Workshop for the Study of Itch
    Earl Carstens; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  32. HYPOGLYCEMIA AND AUTONOMIC NERVOUS SYSTEM FUNCTION
    Roy Freeman; Fiscal Year: 2007
    ..Thus, the broad long term objectives of the proposal are to fully understand the mechanisms and consequences of hypoglycemia associated autonomic failure with the ultimate goal of finding an efficacious treatment. ..
  33. A THERMAL PROBE METHOD FOR STAGING DIABETIC NEUROPATHY
    William Kennedy; Fiscal Year: 2002
    ..abstract_text> ..
  34. AGING AND PERFORMANCE OF COGNITIVE AND PERCEPTUAL TASKS
    GEORGE ANDERSEN; Fiscal Year: 2007
    ..The results of this research will be beneficial in understanding the increased accident risk associated with age. ..
  35. Trigeminal Mechanisms of Oral Irritation
    Earl Carstens; Fiscal Year: 2009
    ..In a corresponding animal study, we will determine if responses of neurons in the n. tractus solitarius (NTS), a taste relay, are reduced by intraoral capsaicin ..
  36. Neural Mechanisms of Motion Sensitivity in V1 and MT
    LUIS LESMES; Fiscal Year: 2007
    ..abstract_text> ..
  37. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2007
    ..Not all schizophrenia patients have olfactory dysfunction or social deficits and we also expect to discern homogeneous subgroups within the broader diagnosis of schizophrenia. [unreadable] [unreadable]..
  38. Sensory Re-training following Orthognathic Surgery
    Ceib Phillips; Fiscal Year: 2005
    ..Our primary focus will be on the patient's perception of the negative impact of altered sensation on daily life. ..
  39. Neurobehavioral correlates of bipolar disorder
    BRIAN O DONNELL; Fiscal Year: 2006
    ..abstract_text> ..
  40. Extrastriate Visual Cortex Deficits in Amblyopia
    ERWIN WONG; Fiscal Year: 2006
    ..Understanding amblyopia and its neural basis may lead to improved diagnosis and treatment. ..
  41. METHODS TO DIAGNOSE AND EVALUATE THERAPY FOR DIABETES
    William Kennedy; Fiscal Year: 2001
    ..If NGF can enhance reinnervation in the skin wound these methods may be useful to evaluate the results of clinical therapeutic trials. ..
  42. Chemosensory Communication of Emotion in Humans
    Denise Chen; Fiscal Year: 2005
    ..It opens up the possibility that olfactory deficit, often conceptualized as a sensory process, may have a more direct social basis and link to mental health (affective disorder) than is currently appreciated. ..
  43. Visual Processing in Schizophrenia and SPD
    BRIAN O DONNELL; Fiscal Year: 2009
    ..These findings may identify neurobehavioral deficits common to SZ and SPD, as well as features which differentiate these disorders. ..
  44. VISUAL ORGANIZATION--BEYOND LOCAL MECHANISMS
    Preeti Verghese; Fiscal Year: 2001
    ..Motion processing is critical for mobility in a structured environment. Thus, there results may assist in the design of devices and training procedures that enhanced mobility in individuals suffering from low vision. ..
  45. TMS in the Management of Postoperative Pain
    Jeffrey J Borckardt; Fiscal Year: 2010
    ..Thus, new interventions that have the potential to reduce reliance on postoperative morphine in this patient population such as TMS need to be explored. ..
  46. A System for Study of Pediatric Visual Pathways
    Anne Fulton; Fiscal Year: 2004
    ..With these studies as a whole, we expect to obtain new knowledge about the processes that govern vision and its development in these pediatric disorders. ..
  47. Retcam 120 Wide Field Digital Imaging System
    Anne Fulton; Fiscal Year: 2002
    ..The minor users will take advantage of the wide field images as well as the highly magnified views of the macula and optic nerve head (optic disc), including the fluorescein capability. ..
  48. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2001
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  49. PERIPHERAL GUSTATORY PROCESSING
    MARION ELIZABETH FRANK; Fiscal Year: 2010
    ..Also, elimination of taste disorders would improve the quality of life that depends on enjoyment of food and drink, a universal human need contributing much to human sociality. ..
  50. Peptidergic Neurotransmission in the Spinal Cord
    VIRGINIA SEYBOLD; Fiscal Year: 2009
    ..If the hypothesis is proven to be true, the data will provide evidence for a new therapeutic strategy that may be effective in treating peripheral inflammatory diseases. ..
  51. Aging and temporal processing: A multi-modality study
    Larry E Humes; Fiscal Year: 2010
    ..Structural equation modeling will be used to examine the correlations between measures and address the degree to which different modalities share a common temporal processing mechanism that is affected by age. ..
  52. HEADGEAR MONITORING FOR ORTHODONTICS
    Douglas Ramsay; Fiscal Year: 2002
    ..Feedback on compliance will be readily available to patients, parents, and orthodontists. Improving compliance with headgear wear may have clinically beneficial consequences. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
  53. Replacing Pierce Lab Animal Care Air Handling Facility
    Lawrence Marks; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  54. Long-range processing in dorsal-occipital cortex
    Christopher Tyler; Fiscal Year: 2005
    ..The final project will introduce a clinical component, quantifying symmetry-blindness in neurological patients with relevant lesions, together with comparison studies in matched controls. ..
  55. Taste psychophysics of bitter phytochemicals
    MIRIAM LINSCHOTEN; Fiscal Year: 2005
    ..Furthermore, food preference data will be gathered. It is anticipated that this study will result in safe and usable ranges of stimulation for each of the phytochemicals, so that in the future data from children can be obtained. ..
  56. Epidermal Innervation as an Outcome Measure
    David Herrmann; Fiscal Year: 2006
    ..Dr. Herrmann will also examine a method to simplify the analysis of skin biopsy specimens, for easier application in large clinical trials. ..
  57. COMMONALITIES IN TOUCH, HEARING,VISION AND TASTE
    Lawrence Marks; Fiscal Year: 2004
    ....
  58. Comparison of post-SCI locomotor training techniques
    EDELLE FIELD FOTE; Fiscal Year: 2006
    ..In addition, they will provide information about neural and cardiorespiratory bases of these functional changes. ..
  59. Short-term Training Students-Health Professional Schools
    KENNETH CIUFFREDA; Fiscal Year: 2006
    ..Trainees will consist of optometry students who have just completed either their first or second professional years, and have done well academically (3.5 gpa or better). All will have an undergraduate degree, generally in the sciences. ..
  60. Planning a Clinical Trial on Low Vision Rehabilitation
    Cynthia Owsley; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  61. Experience Dependent Plasticity of The Developing Cortex
    RON FROSTIG; Fiscal Year: 2007
    ..Further, such results would help in reassessment of the appropriateness of SC-raised rats to serve as models for the normal human brain. ..
  62. In-Vivo Confocal Imaging of Meissner's Corpuscles as a Measure of HIV Neuropathy
    David Herrmann; Fiscal Year: 2008
    ..In-vivo RCM of MCs may prove to have wide application for early identification of sensory peripheral neuropathies, and to assess effectiveness of therapy. [unreadable] [unreadable] [unreadable]..
  63. A New Technique for Central Visual Field Analysis
    Lei Liu; Fiscal Year: 2007
    ..5) Establish the relationship between the findings of the RDAT and existing field tests. The long-term goal is to develop a low-cost, easy-to-use, and widely accessible clinical tool for evaluating the macula. ..