Genomes and Genes
Summary: The smallest difference which can be discriminated between two stimuli or one which is barely above the threshold.
Publications226 found, 100 shown here
- From physical time to the first and second moments of psychological timeS Grondin
Ecole de Psychologie, Universite Laval, Quebec, Canada
Psychol Bull 127:22-44. 2001..Weber's law is a useful guide for studying psychological time, but it is also reasonable to assume that more than one so-called central timekeeper could contribute to perceiving time...
- Adaptive psychophysical proceduresB Treutwein
Institut fur Medizinische Psychologie, Ludwig Maximilians Universitat Munchen, Germany
Vision Res 35:2503-22. 1995..This review tries to illuminate the historical background of adaptive procedures, explain their differences and similarities, and provide criteria for choosing among the various techniques...
- Subtractive and divisive inhibition: effect of voltage-dependent inhibitory conductances and noiseB Doiron
Physics Department, University of Ottawa, Canada
Neural Comput 13:227-48. 2001..A simple leaky integrate-and-fire type model that incorporates the voltage dependence supports the results from our full ionic simulations...
- Discriminating time intervals presented in sequences marked by visual signalsS Grondin
Ecole de Psychologie, Universite Laval, Quebec, Canada
Percept Psychophys 63:1214-28. 2001..With both methods, the increase was well described by Weber's law--the Weber fraction was roughly constant--between 600 and 900 msec (Experiment 2), whereas between 900 and 1,200 msec (Experiment 3), the Weber fraction increased...
- Duration discrimination in crossmodal sequencesSimon Grondin
Ecole de Psychologie, Universite Laval, Quebec, QC G1A 0V6, Canada
Perception 38:1542-59. 2009..Finally, presenting a fixed interval in the first sequence resulted in better discrimination than presenting a variable interval in the first sequence. Implications for theories of timing are discussed...
- Membrane and firing properties of avian medial vestibular nucleus neurons in vitroS Du Lac
Department of Physiology, W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco 94143 0444, USA
J Comp Physiol A 176:641-51. 1995..These properties appear identical to those of rodent MVN neurons, suggesting that the composition and distribution of ion channels in the MVN neuronal membrane has been highly conserved across vertebrate species...
- Topiramate and cortical excitability in humans: a study with repetitive transcranial magnetic stimulationM Inghilleri
Dipartimento Scienze Neurologiche, Universita di Roma La Sapienza, Rome, Italy
Exp Brain Res 174:667-72. 2006....
- Post-spike distance-to-threshold trajectories of neurones in monkey motor cortexDaniel Z Wetmore
Neuroscience Graduate Program, Stanford University School of Medicine, Stanford, CA 94305, USA
J Physiol 555:831-50. 2004..This could act to enhance synchronized oscillatory discharge among populations of cells at functionally relevant frequencies...
- Biochemical signaling networks decode temporal patterns of synaptic inputUpinder S Bhalla
National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India
J Comput Neurosci 13:49-62. 2002..Thus the synaptic signaling network may function as a temporal decoder that transforms patterns from the time domain into the domain of chemical signaling. This may underlie different synaptic responses to different stimulus patterns...
- Effect of volitional inhibition on cortical inhibitory mechanismsYoung H Sohn
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
J Neurophysiol 88:333-8. 2002..The present results demonstrate that volitional inhibition enhances SICI but reduces LICI nonselectively. These results suggest that these two inhibitory mechanisms act differently during execution and suppression of voluntary movements...
- Flumazenil does not affect intracortical motor excitability in humans: a transcranial magnetic stimulation studyH Y Jung
Department of Rehabilitation Medicine, Inha University College of Medicine, Inchon, South Korea
Clin Neurophysiol 115:325-9. 2004..One inhibitory mechanism is supported by activity at benzodiazepine (BZP) receptors. In this study we investigate whether or not the BZP antagonist, flumazenil, increases cortical motor excitability in humans...
- The effects of prolonged intracortical microstimulation on the excitability of pyramidal tract neurons in the catDouglas B McCreery
Huntington Medical Research Institutes, Neural Engineering Laboratory, Pasadena, CA 91105, USA
Ann Biomed Eng 30:107-19. 2002....
- Finite element bidomain model of epiretinal stimulationSaiful A Joarder
Faculty of Engineering, University of Newcastle, Callaghan, NSW 2038, Australia
Conf Proc IEEE Eng Med Biol Soc 2007:1132-5. 2007..Model threshold values were some 2-5 times higher than that of the experimental values...
- Effects of gonadal steroids on the input-output relationship of the corticospinal pathway in humansMarco Bonifazi
Dipartimento di Fisiologia, Universita degli Studi di Siena, 53100, Siena, Italy
Brain Res 1011:187-94. 2004..Our observations confirm that the threshold and gain of corticospinal motoneurones are determined by different neural mechanisms...
- Subtle hemispheric asymmetry of motor cortical inhibitory toneTihomir V Ilic
Clinic of Neurology, J W Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt am Main, Germany
Clin Neurophysiol 115:330-40. 2004..To test whether a novel paired transcranial magnetic stimulation (TMS) protocol (J Physiol 545.1 (2002) 153) detects hemispheric differences in motor cortical inhibition...
- Acute and chronic effects of ethanol on cortical excitabilityA Conte
Department of Neurological Sciences, University of Rome Sapienza, Viale dell Universita, 30, 00185, Rome, Italy
Clin Neurophysiol 119:667-74. 2008..We designed this study to find out whether 5Hz repetitive transcranial magnetic stimulation (rTMS) would disclose changes in cortical plasticity after acute intake of ethanol and in patients with chronic alcohol consumption...
- Modulation of motor cortical excitability following rapid-rate transcranial magnetic stimulationEman M Khedr
Department of Neurology, Assiut University Hospital, Assiut, Egypt
Clin Neurophysiol 118:140-5. 2007..To investigate the effect of high frequency rTMS (25 Hz at 90-100% of resting motor threshold) on the excitability of the motor cortex of healthy human subjects...
- Repetitive firing of rat cerebellar parallel fibres after a single stimulationPhilippe Isope
Laboratoire de Physiologie Cérébrale, UMR CNRS 8118, Centre Universitaire des Saints Peres, 45 Rue des Saints Peres, 75006 Paris, France
J Physiol 554:829-39. 2004..The repetitive activation of the PF by a single stimulation could play a role in the induction of long-term depression...
- Further evidence that a shared efferent collicular pathway drives separate circuits for smooth eye movements and saccadesM Missal
Laboratory of Neurophysiology, School of Medicine, Universite Catholique de Louvain, 5449 Ave Hippocrate, 1200 Brussels, Brussels, Belgium
Exp Brain Res 147:344-52. 2002..We suggest that the same collicular efferent cells carry out the motor command to saccadic and SEM circuits and that the position error originating from the SC may be distributed amongst separate downstream motor systems...
- Synchronization of electrically coupled pairs of inhibitory interneurons in neocortexJaime G Mancilla
Department of Neuroscience, Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, USA
J Neurosci 27:2058-73. 2007..Electrical coupling between cortical interneurons of the same type maintained robust synchronous firing of cell pairs for up to approximately 10% heterogeneity in their intrinsic frequencies...
- Ca2+ imaging of mouse neocortical interneurone dendrites: contribution of Ca2+-permeable AMPA and NMDA receptors to subthreshold Ca2+dynamicsJesse H Goldberg
Department of Biological Sciences, Columbia University, 1212 Amsterdam Avenue, New York, NY 10027, USA
J Physiol 551:67-78. 2003..These data highlight different strategies in dendritic signal processing by distinct classes of interneurones...
- Slow frequency repetitive transcranial magnetic stimulation affects reaction times, but not priming effects, in a masked prime taskF Schlaghecken
Department of Psychology, University of Warwick, Coventry CV4 7AL, UK
Clin Neurophysiol 114:1272-7. 2003..Slow frequency repetitive transcranial magnetic stimulation (rTMS) reduces motor cortex excitability, but it is unclear whether this has behavioural consequences in healthy subjects...
- Frequency-dependent, bi-directional plasticity in motor cortex of human adultsJulia B Pitcher
Department of Physiology, The University of Adelaide, Adelaide, SA 5005, Australia
Clin Neurophysiol 114:1265-71. 2003..To determine whether the plastic changes induced in human motor cortex by afferent stimulation depend on stimulus frequency...
- Construction of a computer model to investigate sawtooth effects in the Purkinje systemEdward J Vigmond
Department of Electrical and Computer Engineering, University of Calgary, Calgary, AB T2N 1N4, Canada
IEEE Trans Biomed Eng 54:389-99. 2007..Thus, the Purkinje system is capable of affecting the defibrillation process, and warrants further experimentation to elucidate its role...
- Effects of 5 Hz subthreshold magnetic stimulation of primary motor cortex on fast finger movements in normal subjectsR Agostino
Department of Neurological Sciences and Neuromed Institute, University of Rome La Sapienza, Viale dell Universita, 30, 00185 Rome, Italy
Exp Brain Res 180:105-11. 2007..Since motor behaviour engages a distributed cortical and subcortical neuronal network, excitatory conditioning of the primary motor cortex is probably not sufficient to influence the behavioural output...
- Neurophysiological study of corticomotor pathways in restless legs syndromeR Quatrale
Department of Neurology, S Anna Hospital, University of Ferrara, C so Giovecca, 203 I 44100 Ferrara, Italy
Clin Neurophysiol 114:1638-45. 2003..Moreover, in primary RLS, these modifications are still debated...
- Cortical correlates of neuromotor development in healthy childrenM A Garvey
Pediatric Movement Disorders Unit, Human Motor Control Section, Motor Neurology Branch, NINDS, National Institutes of Health, 10 Center Drive, 5N226, MSC 1428, Bethesda, MD 20982 1428, USA
Clin Neurophysiol 114:1662-70. 2003..To examine the relationship between acquisition of fine motor skills in childhood and development of the motor cortex...
- Ketamine increases human motor cortex excitability to transcranial magnetic stimulationV Di Lazzaro
Institute of Neurology, Universita Cattolica, Largo A Gemelli 8, 00168 Rome, Italy
J Physiol 547:485-96. 2003..We suggest that the enhancement of human motor cortex excitability to transcranial magnetic stimulation is the effect of an increase in glutamatergic transmission at non-NMDA receptors similar to that described in experimental studies...
- Dipole distance for minimum threshold current to stimulate unmyelinated axons with microelectrodesFrank Rattay
Institute for Analysis and Scientific Computing at the Vienna University of Technology, Wiedner Hauptstr 8 10 101, A 1040 Vienna, Austria
IEEE Trans Biomed Eng 54:158-62. 2007..Spike initiations in straight fibers and retinal ganglion cell axons are investigated...
- Suprathreshold 0.3 Hz repetitive TMS prolongs the cortical silent period: potential implications for therapeutic trials in epilepsyM Cincotta
Unita Operativa di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova, 1 50122, Florence, Italy
Clin Neurophysiol 114:1827-33. 2003..To investigate the after-effects of 0.3 Hz repetitive transcranial magnetic stimulation (rTMS) on excitatory and inhibitory mechanisms at the primary motor cortex level, as tested by single-pulse TMS variables...
- Mathematical models of cochlear nucleus onset neurons: I. Point neuron with many weak synaptic inputsSridhar Kalluri
Harvard University Massachusetts Institute of Technology, Division of Health Sciences and Technology, Eaton Peabody Lab, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
J Comput Neurosci 14:71-90. 2003..These results show a tradeoff, that may be a general property of many neurons, between following rapid stimulus fluctuations and responding without short interspike intervals at the onset of sustained stimuli...
- Short-interval paired-pulse inhibition and facilitation of human motor cortex: the dimension of stimulus intensityTihomir V Ilic
Clinic of Neurology, Johann Wolfgang Goethe University of Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt am Main, Germany
J Physiol 545:153-67. 2002..In contrast, SICF originates through non-synaptic facilitation at the initial axon segment of interneurones along a high-threshold excitatory pathway...
- Long-lasting increase in corticospinal excitability after 1800 pulses of subthreshold 5 Hz repetitive TMS to the primary motor cortexAlexander Peinemann
Department of Neurology, Technische Universitat Munchen, Mohlstrasse 28, D 81675 Munich, Germany
Clin Neurophysiol 115:1519-26. 2004..To study the after effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex (M1) on corticospinal excitability...
- Effect of muscle-fiber velocity recovery function on motor unit action potential properties in voluntary contractionsDario Farina
Center for Sensory Motor Interaction, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7 D 3, DK 9220 Aalborg, Denmark
Muscle Nerve 37:650-8. 2008..This has implications for the use of conduction velocity values measured during voluntary contractions to differentiate patient populations from healthy individuals and for the development of normative data...
- The most likely voltage path and large deviations approximations for integrate-and-fire neuronsLiam Paninski
Department of Statistics, Columbia University, Columbia
J Comput Neurosci 21:71-87. 2006..We close by comparing this most likely voltage path to the true observed subthreshold voltage trace in a case when intracellular voltage recordings are available in vitro...
- Conduction velocity of quiescent muscle fibers decreases during sustained contractionMarco Gazzoni
Laboratorio di Ingegneria del Sistema Neuromusculore, Dipartimento di Elettronica, Politecnico di Torino, Torino, Italy
J Neurophysiol 94:387-94. 2005..6 +/- 5.4%). In conclusion, the contraction-induced modifications in electrophysiological membrane properties of muscle fibers are partly independent on fiber activation...
- Magnetic stimulation of curved nervesA Rotem
A Rotem is with the Weizmann Institute of Science, PO Box 26, Rehovot 76100 Israel
IEEE Trans Biomed Eng 53:414-20. 2006..In the experimental section, we show that magnetic stimulation of the frog sciatic nerve follows our theoretical predictions. Furthermore, the voltage length constant of the nerve can be measured based on these results alone...
- Orderly activation of human motor neurons using electrical ramp prepulsesKristian Hennings
Center for Sensory Motor Interaction SMI, Department of Health Science and Technology, Aalborg University, Frederik Bajers Vej 7 D3 203, 9220 Aalborg, Denmark
Clin Neurophysiol 116:597-604. 2005..The present study investigated the possibility for changing the recruitment order of electrical stimuli with sub-threshold ramp prepulses...
- Corticomotor organisation and motor function in multiple sclerosisGary W Thickbroom
Centre for Neuromuscular and Neurological Disorders M518, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, WA 6009, Australia
J Neurol 252:765-71. 2005..An understanding of motor function in MS should incorporate models of both axonal demyelination and conduction deficits as well as neural plasticity...
- Asynchronous inputs alter excitability, spike timing, and topography in primary auditory cortexPritesh K Pandya
Neuroscience Program, School of Behavioral and Brain Sciences, PO Box 830688, GR 41, University of Texas at Dallas, Richardson, TX 75083 0688, USA
Hear Res 203:10-20. 2005..These results are consistent with earlier observations that sensory input statistics can shape cortical map organization and spike timing...
- Predicting dynamic range and intensity discrimination for electrical pulse-train stimuli using a stochastic auditory nerve model: the effects of stimulus noiseYifang Xu
Department of Electrical and Computer Engineering, Duke University, Durham, NC 27708 0291, USA
IEEE Trans Biomed Eng 52:1040-9. 2005..However, since our predictions indicate that intensity discrimination under noise degrades, overall intensity coding performance may not improve significantly...
- Marked differences in the thermal characteristics of figure-of-eight shaped coils used for repetitive transcranial magnetic stimulationThomas Weyh
Heinz Nixdorf Lehrstuhl für Medizinische Elektronik, Technische Universitat Munchen, Arcisstrasse 21, 80333 Munich, Germany
Clin Neurophysiol 116:1477-86. 2005..To compare the heating behaviour of three figure-of-eight shaped coils during repetitive transcranial magnetic stimulation (rTMS)...
- Repetitive paired-pulse TMS at I-wave periodicity markedly increases corticospinal excitability: a new technique for modulating synaptic plasticityGary W Thickbroom
Centre for Neuromuscular and Neurological Disorders, Queen Elizabeth II Medical Centre, University of Western Australia, Perth, Nedlands, WA 6009, Australia
Clin Neurophysiol 117:61-6. 2006..Our objective was to determine whether prolonged iTMS can increase corticospinal excitability, and whether this form of stimulation can have lasting aftereffects...
- Physiology of modulation of motor cortex excitability by low-frequency suprathreshold repetitive transcranial magnetic stimulationG Heide
Department of Neurology, Friedrich Schiller University, Erlanger Allee 101, 07740 Jena, Germany
Exp Brain Res 171:26-34. 2006..Modulation of motor cortical inhibition did not play a role in explaining the rTMS induced changes in MEP amplitude...
- Dynamic-clamp analysis of the effects of convergence on spike timing. II. Few synaptic inputsMatthew A Xu-Friedman
Department of Biological Sciences, University at Buffalo, State University of New York, USA
J Neurophysiol 94:2526-34. 2005..These significant differences indicate that each means of reducing jitter has advantages and disadvantages and may be more effective for different neurons depending on the properties of their inputs...
- Pathways mediating abnormal intracortical inhibition in Parkinson's diseaseColum D MacKinnon
Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Ann Neurol 58:516-24. 2005..These findings show that the low threshold inhibitory pathways mediating SICI are normal in PD. The suppression of SICI observed at higher CSIs suggests that the threshold of intracortical facilitatory pathways is decreased in PD...
- Predicting spike timing of neocortical pyramidal neurons by simple threshold modelsRenaud Jolivet
Ecol Polytechnique Federale de Lausanne EPFL, School of Computer and Communication Sciences and Brain Mind Institute, Station 15, CH 1015, Lausanne, Switzerland
J Comput Neurosci 21:35-49. 2006....
- Stimulus-response curves of a neuronal model for noisy subthreshold oscillations and related spike generationMartin Tobias Huber
Department of Psychiatry and Psychotherapy, University of Marburg, Rudolf Bultmannstrasse 8, D 35033 Marburg, Germany
Phys Rev E Stat Nonlin Soft Matter Phys 73:041929. 2006..We demonstrate that subthreshold oscillatory neurons in the presence of noise can sensitively and also selectively be tuned by the stimulus-dependent variation of model parameters...
- Preconditioning with transcranial direct current stimulation sensitizes the motor cortex to rapid-rate transcranial magnetic stimulation and controls the direction of after-effectsNicolas Lang
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
Biol Psychiatry 56:634-9. 2004....
- Cortical silent period prolongation in spinocerebellar ataxia type 2 (SCA2)Domenico A Restivo
Department of Neurology, Garibaldi Hospital, Catania, Italy
Funct Neurol 19:37-41. 2004..Thus, the cerebellum seems to exert a pliable physiological influence on the cortico-spinal system through control of inhibitory cortical interneurons...
- A novel electrode array for diameter-dependent control of axonal excitability: a simulation studyZeng Lertmanorat
Neural Engineering Center, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA
IEEE Trans Biomed Eng 51:1242-50. 2004..The diameter selectivity of the electrode array can be controlled by the electrode separation and the method is independent of pulse width...
- A single motor unit recording technique for studying the differential activation of corticospinal volleys by transcranial magnetic stimulationY Terao
Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
Brain Res Brain Res Protoc 7:61-7. 2001..The obtained results accord well with recent epidural recording studies, which lends support to the validity of this method...
- Phasic stimuli evoke precisely timed spikes in intermittently discharging mitral cellsRamani Balu
Dept of Neurosciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA
J Neurophysiol 92:743-53. 2004..These intrinsic properties of mitral cells may be important for precisely timing spikes evoked by phasic stimuli that occur in response to odor presentation in vivo...
- Focal transcranial magnetic stimulation of motor cortex evokes bilateral and symmetrical silent periods in human masseter musclesShapour Jaberzadeh
Discipline of Physiology, School of Molecular and Biomedical Sciences, The University of Adelaide, Adelaide, SA 5005, Australia
Clin Neurophysiol 119:693-703. 2008....
- Corticospinal system excitability at rest is associated with tic severity in tourette syndromeMichael Orth
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
Biol Psychiatry 64:248-51. 2008..However, it is not clear whether these represent abnormalities of specific pathways or reflect a more widespread reduction of motor cortex excitability. Their significance for the clinical phenotype is also unknown...
- Effect of levetiracetam on cortical excitability: a transcranial magnetic stimulation studyC Solinas
Southern Clinical School, Monash University, Clayton, Vic, Australia
Eur J Neurol 15:501-5. 2008..For this purpose, 38 healthy volunteers were assessed in two TMS sessions, before and after an oral dose of 3000 mg LEV...
- Comparative assessment of best conventional with best theta burst repetitive transcranial magnetic stimulation protocols on human motor cortex excitabilityNoman Zafar
Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Street 40, 37075 Gottingen, Germany
Clin Neurophysiol 119:1393-9. 2008..Comparative assessment of best conventional with best theta burst repetitive transcranial magnetic stimulation (rTMS) protocols on human motor cortex excitability...
- Afterhyperpolarization time-course and minimal discharge rate in low threshold motor units in humansChristopher W MacDonell
Graduate Program in Neuroscience, University of Western Ontario, London, ON, Canada
Exp Brain Res 189:23-33. 2008..The calculated AHP time course using the IDR analysis, therefore, is a reasonable estimate and coupled with motor unit properties attained with STA, it provides a powerful method to describe low-threshold motor units...
- Estimating action potential thresholds from neuronal time-series: new metrics and evaluation of methodologiesMurat Sekerli
Laboratory for Neuroengineering and the School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332 0250, USA
IEEE Trans Biomed Eng 51:1665-72. 2004..Our user database of responses may be useful to other investigators interested in developing additional methods in that it quantifies what has often been a subjective estimate...
- Quantification of the corticospinal silent period evoked via transcranial magnetic stimulationLeatha A Damron
Department of Physical Therapy, SUNY Upstate Medical University, United States
J Neurosci Methods 173:121-8. 2008..These results suggest that SPs evoked with a stimulus intensity >or=30% AMT and quantified visually by defining the start of the SP at stimulus delivery or the start of the MEP be utilized to decrease the between visit variability...
- Distal excitability changes in motor axons in amyotrophic lateral sclerosisMiho Nakata
Department of Neurology, Graduate School of Medicine, Chiba University, 1 8 1, Inohana, Chuo Ku, Chiba, 260 8670, Japan
Clin Neurophysiol 117:1444-8. 2006..This study tested the hypothesis that dysfunction of potassium channels is more pronounced in the more distal parts of axons...
- Correspondence between the location of evoked potential generators and sites of maximal sensitivity to stimulationMark M Stecker
Department of Neurology, Geisinger Medical Center, Danville, PA 17822, USA
IEEE Trans Biomed Eng 52:1619-21. 2005..This allows the identification of the point at which an action potential generates a maximal extracellular potential as the point that is stimulated with the lowest threshold...
- Multistage evaluation scale, differential threshold steps and equivalent sensation contours of respiratory flow-resistive load sensationL F Zhang
Department of Aviation Environmental Physiology, Fourth Military Medical College, Xi an
Sci Sin B 31:204-16. 1988..In brief, we have proposed a new way to elucidate the physiological and psychophysical effects of various added resistive loads...
- Dual-energy CT in the diagnosis and quantification of fatty liver: limited clinical value in comparison to ultrasound scan and single-energy CT, with special reference to iron overloadM H Mendler
Department of Gastroenterology, Dupuytren University Hospital, Limoges, France
J Hepatol 28:785-94. 1998..We compared dual-energy CT to ultrasound scan and single-energy CT in the diagnosis and quantification of fatty liver, with special reference to iron overload...
- An evaluation of acrylic complete dentures using the discrimination of elastic bodies or viscous fluidsK Inoue
Department of Dental Materials Science, Kagoshima University Dental School, Japan
J Oral Rehabil 26:608-12. 1999..This indicates that with an increase in the area occupied by dentures in the oral cavity, the value of the differential threshold increased markedly and made food discrimination more difficult...
- Age-dependent normative values for differential luminance sensitivity in automated static perimetry using the Octopus 101Agnes Hermann
Centre for Ophthalmology, University of Tubingen, Tubingen, Germany
Acta Ophthalmol 86:446-55. 2008To determine age-dependent normative differential threshold values for the Octopus 101 instrument and to create a smooth mathematical model characterizing the age-dependency and asymmetry of the hill of vision.
- Accuracy of popular automatic QT interval algorithms assessed by a 'gold standard' and comparison with a Novel method: computer simulation studyAnthony Charles Hunt
PSI HeartSignals Ltd, Institute of Medical Technology, Glasgow Technology Park, PO Box 7043, Glasgow G44 9AB, UK
BMC Cardiovasc Disord 5:29. 2005..There is a scientific imperative to evaluate the most commonly used algorithms with an accurate and objective 'gold standard' and investigate novel automatic algorithms if the commonly used algorithms are found to be deficient...
- Differential threshold of length and response criterion for inspecting irregular objectsC F Chi
Department of Industrial Management, National Taiwan University of Science and Technology, Taipei
Percept Mot Skills 85:723-35. 1997..The standard deviation of the signal distribution was about 1.30 and 1.41 times that of the noise distributions for 'low' and 'high' detectability...
- Impact of hyperventilation on stimulus efficiency during the early phase of an electroconvulsive therapy course: a randomized double-blind studyPrashanth Mayur
Department of Psychiatry, Cumberland Hospital, Sydney, Australia
J ECT 26:91-4. 2010..The question whether hyperventilation during electroconvulsive therapy (ECT) can improve stimulus efficiency is as yet unanswered...
- Differential threshold effects of habitat fragmentation on gene flow in two widespread species of bush cricketsRebecca Lange
Department of Animal Ecology, Justus Liebig University, Heinrich Buff Ring 26 32, D 35392 Giessen, Germany
Mol Ecol 19:4936-48. 2010..These results indicate that even for widespread species in modern agricultural landscapes fragmentation thresholds exist at which gene flow among suitable habitat patches becomes restricted...
- Unification of psychophysical phenomena: the complete form of Fechner's lawK H Norwich
Department of Physiology, University of Toronto, ON, Canada
Percept Psychophys 59:929-40. 1997..triplets of quantities: subjective magnitude of stimulus, subjective just noticeable difference (jnd), and differential threshold. Each of the preceding quantities are functions of the physical magnitude of the stimulus...
- Predominant involvement of a particular group of fingers due to small, cortical infarctionJ S Kim
Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, Korea
Neurology 56:1677-82. 2001..Small cortical strokes may cause predominant weakness restricted to a particular group of fingers. However, clinical, radiologic, and etiopathogenetical studies have rarely been done in these patients...
- Neohesperidin dihydrochalcone is not a taste enhancer in aqueous sucrose solutionsJ H Kroeze
Psychological Laboratory, Utrecht University, Utrecht, The Netherlands and Wageningen Taste and Smell Center, Wageningen University, Wageningen, The Netherlands
Chem Senses 25:555-9. 2000..Finally, in experiment 4, differential threshold functions were constructed with either NHDC or sucrose added...
- Central visual field impairment during and following cystoid macular oedemaC G Kiss
Department of Ophthalmology and Optometry at the Medical University of Vienna, Vienna, Austria
Br J Ophthalmol 92:84-8. 2008..To determine differential light threshold values obtained with the Micro Perimeter 1 (MP1) in uveitis patients suffering from cystoid macular oedema (CMO) and to compare these measures to retinal thickness...
- [Study on resistance to motion artifact in pulse oximetry measurement using segment filter method]Qing Bo Li
Key Laboratory of Precision Opto Mechatronics Technology, Ministry of Education, College of Instrument Science and Opto Electronics Engineering, Beihang University, Beijing 100191, China
Guang Pu Xue Yu Guang Pu Fen Xi 29:2994-7. 2009The authors proposed a method which combined the differential threshold segment with median filter to eliminate abrupt artifact motion interference in the use of pulse oximeter, and further more, by adding the window moving average filter,..
- Stress sensitization and adolescent depressive severity as a function of childhood adversity: a link to anxiety disordersEmmanuel P Espejo
Department of Psychology, University of California Los Angeles, Los Angeles, CA, USA
J Abnorm Child Psychol 35:287-99. 2007The goal of the present study was to determine whether exposure to adversity in childhood contributes to a differential threshold at which stressful life events provoke depressive reactions in adolescence...
- Impaired short temporal interval discrimination in a dyslexic adultL Rousseau
Department of Psychology, Laurentian University, Sudbury, Ontario, Canada
Brain Cogn 46:249-54. 2001..Eight target intervals were used, ranging from 100 to 1,200 ms in duration. At each target interval, the differential threshold (DL) for duration was assessed, with the use of an adaptive psychophysical procedure...
- A novel algorithm for precise identification of spikes in extracellularly recorded neuronal signalsAlessandro Maccione
Department of Neuroscience and Brain Technology, Italian Institute of Technology, Via Morego 30, 16163 Genova, Italy
J Neurosci Methods 177:241-9. 2009..of the signal and looks for the Relative Maximum/Minimum whose peak-to-peak amplitude is above a defined differential threshold and responds to specific requirements...
- Repression of Dpp targets in the Drosophila wing by BrinkerStephanie E Winter
Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
Development 131:6071-81. 2004..Understanding differential threshold responses requires knowledge of how these factors regulate transcription...
- [General indications of middle-ear implants]Angel Osorio Acosta
Servicio de Otorrinolaringologia, Complejo Hospitalario Universitario Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, Espana
Acta Otorrinolaringol Esp 59:14-6. 2008..The differential threshold in frequencies of 500, 1,000, 2,000 and 4,000 Hz should not be above 10 dB in two or more of these ..
- Stochastic probability landscape model for switching efficiency, robustness, and differential threshold for induction of genetic circuit in phage lambdaYoufang Cao
Shanghai Center for Systems Biomedicine, Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China
Conf Proc IEEE Eng Med Biol Soc 2008:611-4. 2008..Our study has revealed likely mechanism of the phage switch network that was previously unknown...
- The physiological basis of transcranial motor cortex stimulation in conscious humansV Di Lazzaro
Institute of Neurology, Universita Cattolica, Largo A Gemelli 8, 00168, Rome, Italy
Clin Neurophysiol 115:255-66. 2004..These differences occur because different structures in the motor cortex have a differential threshold to the different techniques of stimulation...
- [Threshold values for cost-effectiveness ratio and public funding of medical technologies]Mordechai Rabinovich
Maccabi Healthcare Services, Tel Aviv, Israel
Harefuah 146:453-8, 500. 2007..There are several suggestions to set a differential threshold value between countries, associated with their relative wealth, or between diverse disease and treatment ..
- Effect of the moderate exercise on performance in upper/lower limb during long term bed restMasami Miyazaki
Waseda University, Tokorozawa Japan
J Gravit Physiol 9:P147-8. 2002..And then there were not change discriminal ability on differential threshold of weight sensory in scale test in all subjects during head down bed rest...
- Characteristics and mechanisms of the two types of photoelectric differential response of bacteriorhodopsin-based photocellBaoli Yao
State Key Laboratory of Transient Optics Technology, Xi an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, PO Box 80 25, Xi an710068, P R China
Biosens Bioelectron 19:283-7. 2003..It was much faster but much weaker than that described before...
- Permitted and forbidden sets in symmetric threshold-linear networksRichard H R Hahnloser
Howard Hughes Medical Institute, Department of Brain and Cognitive Sciences, MIT E25 210, Cambridge, MA 02139, U S A
Neural Comput 15:621-38. 2003..There is a close correspondence between threshold-linear networks and networks defined by the generalized Lotka-Volterra equations...
- Mathematical models of cochlear nucleus onset neurons: II. model with dynamic spike-blocking stateSridhar Kalluri
Harvard University Massachusetts Institute of Technology, Division of Health Sciences and Technology, Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
J Comput Neurosci 14:91-110. 2003..These results provide a mechanistic rationale for distinguishing between the different physiological classes of CN On neurons...
- [Function of TRP channel as a thermal receptor]Makoto Tominaga
Nihon Seirigaku Zasshi 65:130-7. 2003
- [Is the determination of the defibrillation threshold in patients with an implantable cardioverter-defibrillator still required?]M Licka
Abteilung fur Kardiologie, Angiologie und Pneumologie, Universitatsklinikum Heidelberg, Heidelberg, Germany
Herzschrittmacherther Elektrophysiol 22:209-13. 2011....
- Maturational changes of 5 Hz SSVEPs elicited by intermittent photic stimulationAla Birca
Research Center, Centre Hospitalier Universitaire Mère Enfant Sainte Justine, Universite de Montreal, Montreal, QC, Canada
Int J Psychophysiol 78:295-8. 2010..We interpret these findings in terms of the development of functional interactions between different cortical areas involved in the processing of visual stimuli...
- Microperimetry and fundus autofluorescence in patients with early age-related macular degenerationEdoardo Midena
Department of Ophthalmology, University of Padova, Via Giustiani 2, 35128 Padova, Italy
Br J Ophthalmol 91:1499-503. 2007..The aim of this study was to compare fundus-related sensitivity (microperimetry) and fundus autofluorescence (FAF) of the macular area with drusen and pigment abnormalities in early AMD...
- Influence of subthreshold nonlinearities on signal-to-noise ratio and timing precision for small signals in neurons: minimal model analysisGytis Svirskis
Center for Neural Science, New York University, NY 10003, USA
Network 14:137-50. 2003..Small-signal detection can be significantly improved in noisy neuronal systems by subthreshold negative feedback, serving to suppress false positives...
- Spatial frequency thresholds for face recognition when comparison faces are filtered and unfilteredCharles A Collin
School of Psychology, University of Ottawa, Ottawa, Ontario, Canada
Percept Psychophys 68:879-89. 2006..These results are compatible with the idea that a middle band of SFs will be most useful for any visual task and that the breadth of this optimal middle band will vary depending on task characteristics...
- Stochastic resonance in neuron models: endogenous stimulation revisitedH E Plesser
Max Planck Institut für Strömungsforschung and Fakultät für Physik, Universitat Gottingen, Germany
Phys Rev E Stat Nonlin Soft Matter Phys 63:031916. 2001..This greatly simplifies the mathematical analysis, but we show that stochastic resonance as reported earlier occurs in this model only as a consequence of the reduced dynamics...
- The judgment operation of ratio productionSergio Cesare Masin
Department of General Psychology, Universita di Padova, Padua, Italy
Percept Psychophys 69:1-8. 2007..It was found that this added amount varied nonlinearly with the predefined ratio, implying that ratio productions are nonlinear...
- On the mechanism of the probabilistic nature of ventricular defibrillation thresholdMasaaki Yashima
Division of Cardiology, Cedars Sinai Medical Center, Department of Medicine, School of Medicine, University of California, Los Angeles 90048, USA
Am J Physiol Heart Circ Physiol 284:H249-55. 2003..We conclude that the probabilistic nature of the DFT is related to the amount of myocardium in its VP...
- [Evaluation of adhesive tape containing lidocaine using current perception threshold measurement]A Egi
Department of Anesthesia and Intensive Care, Hiroshima City Asa Hospital, Hiroshima 731-0293
Masui 50:731-5. 2001..However, CPT levels tended to decrease 12 hours after application, regardless of the stimulus rate. From the result, we conclude that Penles provides maximum benefit when applied 6 hours prior to vein puncture...
- Electrophysiological and morphological properties of pre-autonomic neurones in the rat hypothalamic paraventricular nucleusJ E Stern
Department of Pharmacology and Toxicology, Wright State University, 3640 Colonel Glenn Highway, Dayton, OH 45435, USA
J Physiol 537:161-77. 2001....
- Extracellular stimulation of mouse retinal ganglion cells with non-rectangular voltage-controlled waveformsDonald R Cantrell
Northwestern University Interdepartmental Neuroscience Program, Northwestern University, Evanston, IL 60208 USA
Conf Proc IEEE Eng Med Biol Soc 2009:642-5. 2009..Also, the suprathreshold Gaussian and sinusoidal waveforms possessed much lower peaks in current. For this reason, these non-rectangular waveforms may be useful in reducing electrode corrosion and tissue damage...
- Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depressionNeal Lemon
Learning and Memory Research, Medical Faculty, and International Graduate School for Neuroscience, Ruhr University Bochum, 44780 Bochum, Germany
J Neurosci 26:7723-9. 2006..These findings suggest that the dopaminergic system, acting via D1/D5 receptors, gates long-term changes in synaptic strength and that these changes are a critical factor in the acquisition of novel information...
- A randomized comparison of defibrillation thresholds in the right ventricular outflow tract versus right ventricular apexMichael Mollerus
St Mary s Duluth Clinic, Duluth, MN 55805, USA
J Interv Card Electrophysiol 22:221-5. 2008..To determine whether the placement of an implantable cardioverter-defibrillator (ICD) lead in the right ventricular outflow tract (RVOT) has the same defibrillation threshold (DFT) as the right ventricular apex (RVA)...
- Recovery of motoneuron excitability after spinal injuryMonica A Gorassini; Fiscal Year: 2010..Once known, then rehabilitative and/or pharmacological interventions that target motoneuron transduction processes can be developed. ..
- Arrhythmia Assessment Core Lab for IMMEDIATE TrialEric Rashba; Fiscal Year: 2006..End of abstract.) [unreadable] [unreadable]..
- Electrophysiologic effects of late PCI (OAT-EP)Stephen Shorofsky; Fiscal Year: 2005....
- Prognostic significance of T wave variabilityEric Rashba; Fiscal Year: 2006..2) Patients with increased T wave variability derive a greater mortality benefit from prophylactic ICD implantation. ..
- Peripheral Visual Function of Children with Low VisionJOSEPH LAPPIN; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- Assessment and Validation of Tongue Fatigue for SpeechNANCY SOLOMON; Fiscal Year: 2004..This aim will provide evidence to support the clinical relevance of the exacerbation of dysarthria by fatigue and further validate the constant-effort technique as an indicator of fatigue. ..
- Visual Dysfunction in Retinal DegenerationsKenneth R Alexander; Fiscal Year: 2010....
- Dendodendritic computation in the olfactory glomerulusTHOMAS CLELAND; Fiscal Year: 2004..abstract_text> ..
- Elevated Tendency to Appraise Events as Stressful in the Risk for Depression andEMMANUEL ESPEJO; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- The Effects of Resveratrol on PresbyacusisMichael Seidman; Fiscal Year: 2004..Furthermore, these data will provide novel strategies to impart greater wellness in the elderly population and perhaps have a positive effect on health care expenses. ..
- Computational mechanisms in the olfactory bulbTHOMAS CLELAND; Fiscal Year: 2008..Quantitative, integrative results such as these are unlikely to be achieved without the use of computational modeling. ..
- Transducer for indirect blood pressure& O2 saturationLeslie Geddes; Fiscal Year: 2005..The neonatologist, the premature infant physician and the small-infant pediatrician have no single instrument that provides all of these vital signs. ..
- Gene Therapy of Autosomal Recessive RPSimon Petersen Jones; Fiscal Year: 2006..abstract_text> ..
- Crosstalk of hypocretin and MCH in feeding regulationXiao Bing Gao; Fiscal Year: 2010..Ultimately, we hope that our research will benefit those suffering from obesity and obesity-related diseases. ..
- SEX HORMONES AND BODY FLUID REGULATIONNINA STACHENFELD; Fiscal Year: 2003....
- PHYSIOLOGY OF VOCALIZATION SEN IN AUDITORY CORTEXMARK TRAMO; Fiscal Year: 2002....
- Development of Motion Processing in Human InfantsKaren Dobkins; Fiscal Year: 2008..abstract_text> ..
- PKC modulation of calcium current and anesthetic actionGANESAN KAMATCHI; Fiscal Year: 2007..abstract_text> ..
- Hypnotics and the Treatment of Psychiatric DisordersWILLIAM MCCALL; Fiscal Year: 2007..abstract_text> ..
- Physiological Studies of Age-Related Hearing LossRICHARD SCHMIEDT; Fiscal Year: 2007..Taken together, the three aims explore the major causes and effects of metabolic presbyacusis and have direct application to future interventions to help restore age-related hearing loss. [unreadable] [unreadable]..
- Principles of Behavior Change: Choice and ContextEdmund Fantino; Fiscal Year: 2010..The outcomes of these studies are expected to influence the development of improved and individualized forms of behavioral and cognitive therapy as well as guide future research on the neural bases of choice. ..
- Sound Source Segregation and DeterminationRichard Fay; Fiscal Year: 2007..We will focus on understanding the dimensions of neural activity that the brain could use in segregating and integrating simultaneous acoustic components from one or more sources. [unreadable] [unreadable]..
- Information processing at auditory nerve synapsesMatthew A Xu Friedman; Fiscal Year: 2011..This work may lead to improvements both in existing cochlear implants and in implants that stimulate the cochlear nucleus directly. ..
- Imprint Osmoregulation/Maternally-Dehydrated OffspringMina Desai; Fiscal Year: 2007..We will determine the molecular and cellular mechanism(s) and peripheral renal AVP receptor changes. Finally, we will delineate the critical period during which imprinting of the AVP/osmoregulatory pathway occurs. ..
- Auditory nerve responses to electric pulse trainsCharles Miller; Fiscal Year: 2009..We expect the results of this work will guide future designs of cochlear-implant speech processors so that modulated stimuli can be better tailored to the encoding capacity of the user's auditory nerve. ..
- Computational Methods for Fine MappingPaul Marjoram; Fiscal Year: 2007..Bayes methods, which abstract out the effects of the genealogy using hierarchical clustering techniques. ..
- Sound Source Segregation and the Cocktail Party Problem in a Non-human VertebrateMARK BEE; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Origins of Binaural Processing in VertebratesRichard Fay; Fiscal Year: 2008..abstract_text> ..
- SYMPOSIA FOR ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGYElizabeth Keithley; Fiscal Year: 2008..abstract_text> ..
- SPINAL MOTOR CONDUCTION AND RECOVERY AFTER HUMAN SCIBlair Calancie; Fiscal Year: 2009..A slow-release formulation the K-channel blocker 4-aminopyridine will be tested for its effects on conduction in some cases. ..
- Control of Repetitive Movement in Parkinson's DiseaseColum MacKinnon; Fiscal Year: 2009..This project is relevant to public health because the findings will provide a better understanding of the human basal ganglia and its role in the production of disordered movement and help to develop improved treatments. ..
- Mechanisms of Deep Brain Stimulation: Joule Heating and ElectroporationMarom Bikson; Fiscal Year: 2008..These results will improve the success and safety of DBS. [unreadable] [unreadable] [unreadable]..
- Cancer Prevention Mastery-Model Internet InterventionRichard Winett; Fiscal Year: 2008....
- In-Car Technology to Alert Attention-Imparied DriversMatthew Rizzo; Fiscal Year: 2009..The results may be used to design safer automobiles that use new strategies and technologies for collision warning, perceptual augmentation, and attention management. ..
- Vascular Alterations in the Prediabetic ConditionCynthia Cheng; Fiscal Year: 2008....
- CUTANEOUS PATTERN PERCEPTIONJames Craig; Fiscal Year: 2007..The results will also be relevant to the effects that intermediate surfaces such as surgical gloves have on tactile sensitivity and to the measurement and understanding of neurological problems. ..
- MODERATE ALCOHOL USE--CARDIOVASCULAR RISKS AND BENEFITSThomas Giles; Fiscal Year: 2001..The exacerbation or prevention of EIH will be related to drug effects on the cell-signaling pathway. This research can define the cell-signaling pathway in EIH and provide new and novel approaches to treating EIH. ..
- P20-Mediated Suppression of Vascular ForceChristopher Rembold; Fiscal Year: 2004..Many current treatments target smooth muscle to reduce tone. It is possible that targeting the force suppression pathway (i.e. p20) might provide comparable benefits. ..
- BODY WEIGHT SUPPORTED AMBULATION TRAINING AFTER SCIBlair Calancie; Fiscal Year: 2004..abstract_text> ..
- Understanding the Nature of Visual Representation in HumZili Liu; Fiscal Year: 2003..DESCRIPTION: (Applicant's Abstract) No abstract was provided by the applicant. ..
- FEATURES OF STIMULATION IMPORTANT FOR ELECTRICAL HEARINGBRYAN PFINGST; Fiscal Year: 2003..abstract_text> ..
- INNER EAR IMMUNE RESPONSESElizabeth Keithley; Fiscal Year: 2002..Such knowledge will enable clinicians to improve the treatments administered to patients who experience the unfortunate and potentially devastating trauma of rapidly progressing sensorineural hearing loss. ..
- RADIOLOGICAL RESEARCH ACCELERATOR FACILITY (RARAF)David Brenner; Fiscal Year: 2002..abstract_text> ..
- Investigation of numerical abilities in infants with ERPELIZABETH BRANNON; Fiscal Year: 2003..Such insights will contribute to a fuller understanding of the development of mathematical thinking in adults, and may also have important implications for teaching elementary mathematics to children. ..
- CAUSES OF SLEEP-INDUCED BREATHING INSTABILITIESJerome Dempsey; Fiscal Year: 2002..These latter studies conduced in sleep are important to testing the sensitivity of respiratory control mechanisms to mechanical feedback-a problem which remains relatively unexplored, especially in the human. ..
- SEXUAL DIMORPHISM IN SEIZURE CONTROLJANA VELISKOVA; Fiscal Year: 2002..Rats of both sexes and various ages will be used. These studies may lead to the development of new antiepileptic treatments that take into the account sexual age-related differences. ..
- NEUROTROPHIN CONTROL OF REM SLEEPJack Yamuy; Fiscal Year: 2004..This concerted set of experiments will be critical in elucidating the role that neurotrophins play in the control of REM sleep. ..
- Vision and Locomotion in InfantsDavid Anderson; Fiscal Year: 2006..Yet, such a test would permit the identification of babies who have mild or moderate visual or motor impairments so that interventions could be started at ages much earlier than at present. [unreadable] [unreadable]..
- BONY EFFECTS OF TRANSIENT NONSKELETAL ILLNESSRobert Heaney; Fiscal Year: 2001....
- MECHANISMS OF SKELETAL MUSCLE FATIGUEJay Williams; Fiscal Year: 2001..In addition, it will attempt to identify direct links between muscle glycogen levels, CHO metabolism and the fatigue process. ..
- Information Transfer at Auditory Nerve SynapsesMATTHEW XU FRIEDMAN; Fiscal Year: 2005..This work will also provide information for implants that stimulate the brain directly, for patients who lack a functioning auditory nerve. ..
- Validation of rat models for resistant epilepsy therapyWolfgang Loscher; Fiscal Year: 2005..Our goal is to establish standard assays that can be employed by researchers to continue the search for treatments of drug resistant epilepsy. ..
- FUNCTIONAL EFFECTS OF DEAFNESS AND NEURAL STIMULATIONBRYAN PFINGST; Fiscal Year: 2005....
- OPTIMIZATION OF ELECTROCONVULSIVE THERAPYWILLIAM MCCALL; Fiscal Year: 2005....
- Prenatal Corticosteroid Impact on HippocampusLIBOR VELISEK; Fiscal Year: 2004..The data of this proposal will be critical for determining long-term adverse effects of multiple course prenatal corticosteroid therapy and for the ameliorating these effects in the offspring. ..
- Representation of number in infancyElizabeth M Brannon; Fiscal Year: 2010....
- Neurobiologic Study of Psychological Distress & DementiaRobert S Wilson; Fiscal Year: 2010....
- NEURONAL ORGANIZATION OF BASAL GANGLIACharles Wilson; Fiscal Year: 2003..This latter will allow us to determine whether there is an actual mismatch between physiological and anatomical estimates of connectivity (i.e. non-functional synaptic connections). ..
- TRAINING IN APPLIED AND BASIC COGNITIONCAREN ROTELLO; Fiscal Year: 2008..Postdoctoral trainees are selected who can best benefit from the interdisciplinary collaborative research experiences offered by the program. ..
- Changes in cortical neurons and networks in mice overexpressing A betaJack Waters; Fiscal Year: 2008..These studies will provide critical insight into the cellular changes that occur in Alzheimer's disease and the resulting degeneration of neural networks. [unreadable] [unreadable] [unreadable]..
- CENTRAL NEURONAL MECHANISMS--DECOMPENSATED HEMORRHAGEPATRICE GUYENET; Fiscal Year: 2003..Understanding the neurophysiological mechanisms triggered by hypotensive hemorrhage should lead to improved ability to manage this all too frequent clinical problem. ..
- ORGANIZATION OF CENTRAL SYMPATHETIC PATHWAYSPATRICE GUYENET; Fiscal Year: 2008..The research will contribute to the basic physiological knowledge needed to understand how syrr pathetic tone is regulated in health and in diseases such as arrhythmias, hypertension and dysautonomias. ..
- Aging Effects on a-Adrenergic Activity in Female BladderNatalia Dmitrieva; Fiscal Year: 2006..The results of these studies will be the basis for developing a longer research program. ..
- Regulation of Progenenitor Cell Maturation in the CortexLaura Lillien; Fiscal Year: 2007..The targets of Akt- 1 that mediate maturation and/or self-renewal will be addressed in aim 3. ..
- White Matter Change and CNS Process in the ElderlyLisa Silbert; Fiscal Year: 2008..This application proposes a structured didactic mentorship program for the principal investigator, Dr. Lisa Silbert, to ensure her independence as a clinical investigator at the end of the 5-year award period. [unreadable] [unreadable]..
- Auditory Neuroscience Training at Univ. ConnecticutShigeyuki Kuwada; Fiscal Year: 2006..A postdoctoral trainee in this milieu cannot help but flourish to become a productive and creative investigator in his own right. ..