auditory threshold

Summary

Summary: The audibility limit of discriminating sound intensity and pitch.

Top Publications

  1. ncbi Changes in spontaneous neural activity immediately after an acoustic trauma: implications for neural correlates of tinnitus
    A J Noreña
    Department of Physiology and Biophysics, Neuroscience Research Group, University of Calgary, 2500 University Drive NW, Calgary, AB, Canada T2N 1N4
    Hear Res 183:137-53. 2003
  2. pmc Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift
    Larry E Roberts
    Department of Psychology, Neuroscience, and Behaviour, McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1
    J Assoc Res Otolaryngol 9:417-35. 2008
  3. pmc Primary neural degeneration in the Guinea pig cochlea after reversible noise-induced threshold shift
    Harrison W Lin
    Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA
    J Assoc Res Otolaryngol 12:605-16. 2011
  4. ncbi Human auditory steady-state responses
    Terence W Picton
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Canada
    Int J Audiol 42:177-219. 2003
  5. ncbi Changes in spontaneous firing rate and neural synchrony in cat primary auditory cortex after localized tone-induced hearing loss
    Satoshi Seki
    Departments of Physiology and Biophysics, and Psychology, University of Calgary, 2500 University Drive N W, Calgary, AB, Canada T2N 1N4
    Hear Res 180:28-38. 2003
  6. ncbi A major gene affecting age-related hearing loss in C57BL/6J mice
    K R Johnson
    The Jackson Laboratory, Bar Harbor, ME 04609 1500, USA
    Hear Res 114:83-92. 1997
  7. pmc Electrophysiological validation of a human prototype auditory midbrain implant in a guinea pig model
    Minoo Lenarz
    Otorhinolaryngology Department, Medical University of Hannover, Hannover, Lower Saxony 30625, Germany
    J Assoc Res Otolaryngol 7:383-98. 2006
  8. ncbi Ipsilateral electric acoustic stimulation of the auditory system: results of long-term hearing preservation
    Wolfgang K Gstoettner
    Department of Otolaryngology, Johann Wolfgang Goethe University Frankfurt am Main, Frankfurt am Main, Germany
    Audiol Neurootol 11:49-56. 2006
  9. ncbi Self-reported hearing problems among older adults: prevalence and comparison to measured hearing impairment
    Samuli Hannula
    Department of Clinical Medicine, Otorhinolaryngology, University of Oulu, Oulu, Finland
    J Am Acad Audiol 22:550-9. 2011
  10. pmc Aging alters the perception and physiological representation of frequency: evidence from human frequency-following response recordings
    Christopher G Clinard
    Department of Speech and Hearing Sciences, University of Washington, 1417 N E 42nd St, Box 354875, Seattle, WA 98105, USA
    Hear Res 264:48-55. 2010

Detail Information

Publications290 found, 100 shown here

  1. ncbi Changes in spontaneous neural activity immediately after an acoustic trauma: implications for neural correlates of tinnitus
    A J Noreña
    Department of Physiology and Biophysics, Neuroscience Research Group, University of Calgary, 2500 University Drive NW, Calgary, AB, Canada T2N 1N4
    Hear Res 183:137-53. 2003
    ..Moreover, rho was elevated in the Be-Ab2, Ab1-Ab2 and Ab2-Ab2 groups; this increase was significantly correlated to the changes in SFR. The results are discussed in the context of a neural correlate of tinnitus...
  2. pmc Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift
    Larry E Roberts
    Department of Psychology, Neuroscience, and Behaviour, McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1
    J Assoc Res Otolaryngol 9:417-35. 2008
    ..Hearing thresholds measured in age-matched control subjects without tinnitus implicated hearing loss as a factor in tinnitus, although elevated thresholds alone were not sufficient to cause tinnitus...
  3. pmc Primary neural degeneration in the Guinea pig cochlea after reversible noise-induced threshold shift
    Harrison W Lin
    Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA
    J Assoc Res Otolaryngol 12:605-16. 2011
    ....
  4. ncbi Human auditory steady-state responses
    Terence W Picton
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Canada
    Int J Audiol 42:177-219. 2003
    ..These responses are useful for objectively evaluating auditory thresholds, assessing suprathreshold hearing, and monitoring the state of arousal during anesthesia...
  5. ncbi Changes in spontaneous firing rate and neural synchrony in cat primary auditory cortex after localized tone-induced hearing loss
    Satoshi Seki
    Departments of Physiology and Biophysics, and Psychology, University of Calgary, 2500 University Drive N W, Calgary, AB, Canada T2N 1N4
    Hear Res 180:28-38. 2003
    ..A third finding was that exposed animals showed higher spontaneous activity compared to controls regardless of the presence of cortical reorganization. This may be a correlate of tinnitus in the presence of only minor hearing losses...
  6. ncbi A major gene affecting age-related hearing loss in C57BL/6J mice
    K R Johnson
    The Jackson Laboratory, Bar Harbor, ME 04609 1500, USA
    Hear Res 114:83-92. 1997
    ..ABR test results and cochlear histopathology of aged progenitors of these congenic lines are presented. Ahl is the first gene causing late-onset, non-syndromic hearing loss that has been reported in the mouse...
  7. pmc Electrophysiological validation of a human prototype auditory midbrain implant in a guinea pig model
    Minoo Lenarz
    Otorhinolaryngology Department, Medical University of Hannover, Hannover, Lower Saxony 30625, Germany
    J Assoc Res Otolaryngol 7:383-98. 2006
    ..This study confirms that our AMI design is sufficient for ensuring safe and effective activation of the ICC, and warrants further studies to translate the AMI into clinical application...
  8. ncbi Ipsilateral electric acoustic stimulation of the auditory system: results of long-term hearing preservation
    Wolfgang K Gstoettner
    Department of Otolaryngology, Johann Wolfgang Goethe University Frankfurt am Main, Frankfurt am Main, Germany
    Audiol Neurootol 11:49-56. 2006
    ..To evaluate long-term ipsilateral hearing preservation in patients who underwent cochlear implantation for the combined electric acoustic stimulation of the auditory system...
  9. ncbi Self-reported hearing problems among older adults: prevalence and comparison to measured hearing impairment
    Samuli Hannula
    Department of Clinical Medicine, Otorhinolaryngology, University of Oulu, Oulu, Finland
    J Am Acad Audiol 22:550-9. 2011
    ....
  10. pmc Aging alters the perception and physiological representation of frequency: evidence from human frequency-following response recordings
    Christopher G Clinard
    Department of Speech and Hearing Sciences, University of Washington, 1417 N E 42nd St, Box 354875, Seattle, WA 98105, USA
    Hear Res 264:48-55. 2010
    ..Although perception and neural representation concurrently declined, one was not predictive of the other...
  11. ncbi Age-related difference in melodic pitch perception is probably mediated by temporal processing: empirical and computational evidence
    Frank A Russo
    Department of Psychology, Ryerson University, Toronto, Ontario, Canada
    Ear Hear 33:177-86. 2012
    ..In addition, if there are age-related deficits in temporal processing in older adults, this group may have reduced performance relative to younger adults even in the most favorable conditions...
  12. ncbi Speech reception thresholds in noise and self-reported hearing disability in a general adult population
    Cas Smits
    Department of Otolaryngology Audiology, EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands
    Ear Hear 27:538-49. 2006
    ..A secondary objective was to investigate to what extent the functional measurements could be predicted on the basis of the self-reported data...
  13. ncbi Meta-analysis of variables that affect accuracy of threshold estimation via measurement of the auditory steady-state response (ASSR)
    Abreena I Tlumak
    Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh 15260, USA
    Int J Audiol 46:692-710. 2007
    ..In addition to these findings, another practical outcome of this study was the development of various summary tables of the data analysed from the literature sampled...
  14. pmc Effects of carrier pulse rate and stimulation site on modulation detection by subjects with cochlear implants
    Bryan E Pfingst
    Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor 48109 0506, USA
    J Acoust Soc Am 121:2236-46. 2007
    ..The data suggest a distinct disadvantage to using carrier pulse rates as high as 4000 pps. Stimulation site should be considered in evaluating modulation detection ability...
  15. pmc Relationship between swim bladder morphology and hearing abilities--a case study on Asian and African cichlids
    Tanja Schulz-Mirbach
    Department of Behavioral Biology, University of Vienna, Vienna, Austria
    PLoS ONE 7:e42292. 2012
    ..This study investigates the diversity of swim bladder morphology in four Asian and African cichlid species and analyzes how this diversity affects their hearing sensitivity...
  16. ncbi Corticofugal modulation of amplitude domain processing in the midbrain of the big brown bat, Eptesicus fuscus
    Philip H S Jen
    Division of Biological Sciences and Interdisciplinary Neuroscience Program, University of Missouri, Columbia, MO 65211, USA
    Hear Res 184:91-106. 2003
    ..However, corticofugal modulation of collicular amplitude sensitivity is primarily dependent upon the difference but not the absolute amplitude sensitivity between collicular and cortical neurons...
  17. ncbi Are hearing sensitivities of freshwater fish adapted to the ambient noise in their habitats?
    Sonja Amoser
    University of Vienna, Department of Neurobiology and Behavior, Althanstrasse 14, 1090 Vienna, Austria
    J Exp Biol 208:3533-42. 2005
    ..Hearing in non-specialists such as perch, on the other hand, is only slightly or not at all impaired in all habitats...
  18. pmc Effects of stimulation rate, mode and level on modulation detection by cochlear implant users
    John J Galvin
    Department of Auditory Implants and Perception, House Ear Institute, 2100 West Third Street, Los Angeles, CA 90057, USA
    J Assoc Res Otolaryngol 6:269-79. 2005
    ..Lower stimulation rates may provide better recognition of weak acoustic envelope information...
  19. pmc Mechanisms and genes in human strial presbycusis from animal models
    Kevin K Ohlemiller
    Fay and Carl Simon Center for the Biology of Hearing and Deafness Central Institute for the Deaf at Washington University, Department of Otolaryngology, St Louis, MO 63110, USA
    Brain Res 1277:70-83. 2009
    ..Additional studies of these and other inbred mouse and rat models should reveal candidate processes and genes that promote EP decline in humans...
  20. ncbi Auditory cortical neuron response differences under isoflurane versus pentobarbital anesthesia
    S W Cheung
    W M Keck Center for Integrative Neuroscience, Department of Otolaryngology, University of California, San Francisco 94143 0342, USA
    Hear Res 156:115-27. 2001
    ..Compared to pentobarbital, isoflurane appears to have a profound impact on response sensitivity and temporal response properties of auditory cortical neurons...
  21. ncbi Changes over time in electrical stimulation levels and electrode impedance values in children using the Nucleus 24M cochlear implant
    Yael Henkin
    Department of Communication Disorders, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Int J Pediatr Otorhinolaryngol 67:873-80. 2003
    ..e. threshold levels, comfortable levels, dynamic range, and electrode impedance values during the 1st year post-implantation, in children using the Nucleus 24M cochlear implant system...
  22. ncbi Temporal processing and speech recognition in cochlear implant users
    Qian Jie Fu
    Department of Auditory Implants and Perception, House Ear Institute, 2100 West Third Street, Los Angeles, CA 90057, USA
    Neuroreport 13:1635-9. 2002
    ..In correlating a basic psychophysical measure to speech performance, these results should contribute toward improved speech processor design and rehabilitation tools for cochlear implant patients...
  23. ncbi Impaired cochlear function correlates with the presence of tinnitus and its estimated spectral profile
    Xiang Zhou
    Department of Biomedical Engineering, The City College of the City University of New York, New York, NY 10031, USA
    Hear Res 277:107-16. 2011
    ..83 ± 0.09, N = 19). Thus, cochlear function is strongly associated with the tinnitus percept and measures of cochlear function using DPOAEs provide additional diagnostic information over perceptual thresholds alone...
  24. pmc Interaural phase and level difference sensitivity in low-frequency neurons in the lateral superior olive
    Daniel J Tollin
    Department of Physiology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 25:10648-57. 2005
    ..The data demonstrate that low-frequency LSO neurons of cat are not monaural and can exhibit contralateral inhibition like their high-frequency counterparts...
  25. ncbi A practical method of predicting the loudness of complex electrical stimuli
    Colette M McKay
    Department of Otolaryngology, The University of Melbourne, 384 388 Albert Street, East Melbourne 3002, Australia
    J Acoust Soc Am 113:2054-63. 2003
    ..The following experiments confirmed the accuracy of the method using multiple-electrode stimuli with various patterns of electrode locations and current levels...
  26. ncbi The effect of spatial separation on informational and energetic masking of speech
    Tanya L Arbogast
    Department of Communication Disorders and The Hearing Research Center, Boston University, Massachusetts 02215, USA
    J Acoust Soc Am 112:2086-98. 2002
    ..These results suggest that, in these conditions, the advantage due to spatial separation of sources is greater for informational masking than for energetic masking...
  27. ncbi Advantages and caveats when recording steady-state responses to multiple simultaneous stimuli
    M Sasha John
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Ontario
    J Am Acad Audiol 13:246-59. 2002
    ..Although these interactions are interesting physiologically, their small size means that they do not lessen the advantages of the multiple-stimulus approach...
  28. ncbi Water-soluble Coenzyme Q10 formulation (Q-ter) promotes outer hair cell survival in a guinea pig model of noise induced hearing loss (NIHL)
    Anna Rita Fetoni
    Institute of Otolaryngology, School of Medicine, Catholic University of Rome, Largo F Vito 1, 00168 Rome, Italy
    Brain Res 1257:108-16. 2009
    ..These data confirm that solubility of Coenzyme Q(10) improves the ability of CoQ(10) in preventing oxidative injuries that result from mitochondrial dysfunction...
  29. ncbi How does tripus extirpation affect auditory sensitivity in goldfish?
    Friedrich Ladich
    Institute of Zoology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    Hear Res 182:119-29. 2003
    ..This suggests that the auditory system in otophysines improves with increasing frequency due to a more efficient connection between the swimbladder and inner ear ensured by the Weberian ossicles...
  30. pmc Forward masking estimated by signal detection theory analysis of neuronal responses in primary auditory cortex
    Ana Alves-Pinto
    MRC Institute of Hearing Research, Science Road, University Park, Nottingham, Nottinghamshire, UK
    J Assoc Res Otolaryngol 11:477-94. 2010
    ..Masking was largely attributable to a reduction in the responses to the probe, rather than either a persistence of the masker responses or an increase in the variability of probe responses...
  31. ncbi Informational and energetic masking effects in the perception of multiple simultaneous talkers
    D S Brungart
    Air Force Research Laboratory, Human Effectiveness Directorate, Wright Patterson AFB, Ohio 45433, USA
    J Acoust Soc Am 110:2527-38. 2001
    ..The results of these experiments demonstrate how monaural factors may play an important role in the segregation of speech signals in multitalker environments...
  32. ncbi Effects of hearing aid fitting on the perceptual characteristics of tinnitus
    G Moffat
    Laboratoire de Neurobiologie Integrative et Adaptative, UMR CNRS 6149, 3 Place Victor Hugo, Marseille, F 13331 Cedex 03, France
    Hear Res 254:82-91. 2009
    ..This limit to the malleability of the tinnitus percept may arise from either the extent of hearing deficits or the duration and robustness of the neuroplastic changes that originally give rise to tinnitus...
  33. ncbi Development of vocalization, auditory sensitivity and acoustic communication in the Lusitanian toadfish Halobatrachus didactylus
    Raquel O Vasconcelos
    Departamento de Biologia Animal e Centro de Biologia Ambiental, Faculdade de Ciências da Universidade de Lisboa Bloco C2 Campo Grande, 1749 0161 Lisbon, Portugal
    J Exp Biol 211:502-9. 2008
    ....
  34. ncbi Neural population coding of sound level adapts to stimulus statistics
    Isabel Dean
    Department of Physiology and University College London Ear Institute, UK
    Nat Neurosci 8:1684-9. 2005
    ..This extends the range of sound levels that can be accurately encoded, fine-tuning hearing to the local acoustic environment...
  35. ncbi Audiogram notches in noise-exposed workers
    Peter M Rabinowitz
    Yale Occupational and Environmental Medicine Program, Yale University School of Medicine, 135 College Street, Suite 392, New Haven, CT 06510, USA
    Ear Hear 27:742-50. 2006
    ..Diagnostic criteria for noise-induced hearing loss include the audiometric notch, yet no standardized definition exists. This study tested whether objective notch metrics could match the clinical judgments of an expert panel...
  36. ncbi A targeted deletion in alpha-tectorin reveals that the tectorial membrane is required for the gain and timing of cochlear feedback
    P K Legan
    School of Biological Sciences, The University of Sussex, Falmer, Brighton, United Kingdom
    Neuron 28:273-85. 2000
    ..Thus, the tectorial membrane ensures that outer hair cells can effectively respond to basilar membrane motion and that feedback is delivered with the appropriate gain and timing required for amplification...
  37. ncbi Level invariant representation of sounds by populations of neurons in primary auditory cortex
    Srivatsun Sadagopan
    Laboratory of Auditory Neurophysiology, Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 28:3415-26. 2008
    ..These response properties lead to a level-invariant representation of sounds over the population of A1 neurons. Such a representation is an important step for robust feature recognition in natural environments...
  38. pmc Differential expression of apoptosis-related genes in the cochlea of noise-exposed rats
    B H Hu
    Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, NY 14214, USA
    Neuroscience 161:915-25. 2009
    ..These constitutively expressed genes, together with the inducible genes, may participate in the induction of cochlear apoptotic activity...
  39. ncbi Modeling auditory processing of amplitude modulation. I. Detection and masking with narrow-band carriers
    T Dau
    Carl von Ossietzky Universitat Oldenburg, AG Medizinische Physik, Germany
    J Acoust Soc Am 102:2892-905. 1997
    ....
  40. ncbi Screened and unscreened hearing threshold levels for the adult population: results from the Nord-Trøndelag Hearing Loss Study
    Bo Engdahl
    Division on Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Int J Audiol 44:213-30. 2005
    ....
  41. ncbi Normative findings of electrically evoked compound action potential measurements using the neural response telemetry of the Nucleus CI24M cochlear implant system
    D Cafarelli Dees
    Cochlear Europe Ltd, London, UK
    Audiol Neurootol 10:105-16. 2005
    ..Correlation between these two factors and the same factors describing the T- and C-levels appeared to be moderate, in the range of 0.5-0.6...
  42. ncbi Psychometric normalization of a hyperacusis questionnaire
    S Khalfa
    Neurosciences and Sensory Systems, Lyon, France
    ORL J Otorhinolaryngol Relat Spec 64:436-42. 2002
    ..This new psychometric tool should further be tested on hyperacusic patients to verify its relevance in pathology and define the involvement of the three dimensions statistically obtained on the hyperacusis symptomatology...
  43. ncbi Perceptual consequences of disrupted auditory nerve activity
    Fan Gang Zeng
    Department of Anatomy, 364 Med Surge II, Univ of California, Irvine, CA 92697 1275, USA
    J Neurophysiol 93:3050-63. 2005
    ..These results not only show the unique contribution of neural synchrony to sensory perception but also provide guidance for translational research in terms of better diagnosis and management of human communication disorders...
  44. ncbi Changes in neuronal activity of the inferior colliculus in rat after temporal inactivation of the auditory cortex
    J Popelar
    Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Physiol Res 52:615-28. 2003
    ..The results reveal the complex changes that appear in IC neuronal activity after functional ablation of the ipsilateral auditory cortex...
  45. ncbi Audition in sciaenid fishes with different swim bladder-inner ear configurations
    John U Ramcharitar
    Department of Biology and Neuroscience and Cognitive Science Program, University of Maryland, College Park, Maryland 20742, USA
    J Acoust Soc Am 119:439-43. 2006
    ..There were, however, no significant interspecific differences in auditory sensitivity for stimuli between 200 and 700 Hz. These data support the hypothesis that the swim bladder can potentially expand the frequency range of detection...
  46. ncbi Selectivity of neural stimulation in the auditory system: a comparison of optic and electric stimuli
    Agnella D Izzo
    Northwestern University, Biomedical Engineering, 2145 Sheridan Road, Tech E310, Evanston, Illinois 60208, USA
    J Biomed Opt 12:021008. 2007
    ..In the auditory system, optical stimulation of nerves could have a significant impact on the performance of cochlear implants, which can be limited by the electric current spread...
  47. ncbi A novel Z-score-based method to analyze candidate genes for age-related hearing impairment
    Erik Fransen
    Department of Medical Genetics, University of Antwerp, Belgium
    Ear Hear 25:133-41. 2004
    ..Here we define and validate a quantitative trait value for ARHI, correcting for age and gender, to allow the genetic study of ARHI as a quantitative trait...
  48. ncbi Prevalence and significance of high-frequency hearing loss in subjectively normal-hearing patients with tinnitus
    Dong Kee Kim
    Department of Otolaryngology Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea
    Ann Otol Rhinol Laryngol 120:523-8. 2011
    ....
  49. ncbi Development of cochlear amplification, frequency tuning, and two-tone suppression in the mouse
    Lei Song
    Boys Town National Research Hospital, Omaha, Nebraska 68131, USA
    J Neurophysiol 99:344-55. 2008
    ..These findings support a traditional view of development in which the maturation of passive transduction precedes the maturation of active mechanics in the most sensitive region of the mouse cochlea...
  50. pmc Sensitivity to interaural correlation of single neurons in the inferior colliculus of guinea pigs
    Trevor M Shackleton
    MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, UK
    J Assoc Res Otolaryngol 6:244-59. 2005
    ..The data suggest that, unlike pure tone interaural time difference, discrimination of a population measure is required to account for behavioral interaural correlation discrimination performance...
  51. ncbi The decision process in forward-masked intensity discrimination: evidence from molecular analyses
    Daniel Oberfeld
    Department of Psychology, Johannes Gutenberg Universitat Mainz, Mainz, Germany
    J Acoust Soc Am 125:294-303. 2009
    ..2005). "Effect of variability in level on forward masking and on increment detection," J. Acoust. Soc. Am. 118, 325-337] are discussed...
  52. ncbi Auditory processing, speech perception and phonological ability in pre-school children at high-risk for dyslexia: a longitudinal study of the auditory temporal processing theory
    Bart Boets
    Centre for Disability, Special Needs Education and Child Care, Katholieke Universiteit Leuven, Belgium
    Neuropsychologia 45:1608-20. 2007
    ....
  53. ncbi Speech-in-noise screening tests by internet, part 1: test evaluation for noise-induced hearing loss identification
    Monique C J Leensen
    Clinical and Experimental Audiology, ENT Department, Academic Medical Centre AMC, Amsterdam, The Netherlands
    Int J Audiol 50:823-34. 2011
    ..These tests can be highly valuable in increasing the awareness and prevention of noise-induced hearing loss (NIHL). This study evaluates these online speech-in-noise tests and investigates their potential to detect NIHL...
  54. pmc Regulated expression of surface AMPA receptors reduces excitotoxicity in auditory neurons
    Zhiqiang Chen
    Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, USA
    J Neurophysiol 102:1152-9. 2009
    ..These results suggest that the reduction of surface AMPAR by endocytosis during excitatory stimulation plays an important role in limiting the excitotoxic damage to the neuron...
  55. pmc Effects of hearing preservation on psychophysical responses to cochlear implant stimulation
    Stephen Y Kang
    Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109 5616, USA
    J Assoc Res Otolaryngol 11:245-65. 2010
    ..We hypothesize that the differences in detection thresholds between groups are caused by the electrical activation of the hair cells in group I animals and/or differences between groups in the condition of the spiral ganglion neurons...
  56. ncbi Brain stem responses to speech in younger and older adults
    Kathy R Vander Werff
    Department of Communication Sciences and Disorders, Syracuse University, Syracuse, NY 13244, USA
    Ear Hear 32:168-80. 2011
    ..In addition, the effect of minimal peripheral hearing loss on the auditory brain stem response (ABR) evoked by speech stimuli and interactions with aging were examined...
  57. ncbi Individual differences in auditory abilities
    Gary R Kidd
    Department of Speech and Hearing Sciences, Indiana University, Bloomington, Indiana 47405, USA
    J Acoust Soc Am 122:418-35. 2007
    ..This FSR ability is independent of normal variation in both spectral-temporal acuity and of general intellectual ability...
  58. ncbi Auditory target detection in reverberation
    Patrick M Zurek
    Sensimetrics Corporation, 48 Grove Street, Somerville, Massachusetts 02144, USA
    J Acoust Soc Am 115:1609-20. 2004
    ..The success of these detection models in the present well-controlled reverberant conditions suggests that they can be used to incorporate listening mode and source location as factors in speech-intelligibility predictions...
  59. pmc The effect of supplemental dietary taurine on tinnitus and auditory discrimination in an animal model
    Thomas J Brozoski
    Division of Otolaryngology, Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
    Hear Res 270:71-80. 2010
    ..These results are consistent with the hypothesis that taurine attenuates tinnitus and improves auditory discrimination by increasing inhibitory tone and decreasing noise in the auditory pathway...
  60. ncbi Central neural activity in rats with tinnitus evaluated with manganese-enhanced magnetic resonance imaging (MEMRI)
    Thomas J Brozoski
    Division of Otolaryngology, Southern Illinois University School of Medicine, Springfield, IL 62794 9629, USA
    Hear Res 228:168-79. 2007
    ..It was concluded that chronic tinnitus in rats is associated with focal activity elevation in the auditory brainstem and increased activity in the paraflocculus that may be unique to tinnitus...
  61. pmc Development of functional organization of the pallid bat auditory cortex
    Khaleel A Razak
    Department of Zoology and Physiology, University of Wyoming, Laramie, WY 82071, USA
    Hear Res 228:69-81. 2007
    ....
  62. ncbi Visual stimuli can impair auditory processing in cochlear implant users
    Francois Champoux
    Centre de Recherche en Neuropsychologie et Cognition, Universite de Montreal, Montreal, Quebec, Canada
    Neuropsychologia 47:17-22. 2009
    ..These findings raise several questions with regards to the rehabilitation of cochlear implant users...
  63. pmc Neural representation of pitch salience in the human brainstem revealed by psychophysical and electrophysiological indices
    Ananthanarayan Krishnan
    Department of Speech Language Hearing Sciences, Purdue University, West Lafayette, IN 47907 2038, USA
    Hear Res 268:60-6. 2010
    ..We infer that information related to pitch salience may emerge early along the auditory pathway and is likely rooted in pre-attentive, sensory-level processing...
  64. pmc Detection of pulse trains in the electrically stimulated cochlea: effects of cochlear health
    Bryan E Pfingst
    Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, Michigan 48109 5616, USA
    J Acoust Soc Am 130:3954-68. 2011
    ..The amount of multipulse integration was correlated with the health of the implanted cochlea with implications for perception of more complex prosthetic stimuli...
  65. pmc Temporal modulation transfer functions in cochlear implantees using a method that limits overall loudness cues
    Matthew Fraser
    School of Psychological Sciences, The University of Manchester, Manchester M13 9PL, UK
    Hear Res 283:59-69. 2012
    ..When detection thresholds were expressed as a proportion of dynamic range, there was no effect of carrier rate for the lowest modulation frequency (50 Hz) at either level...
  66. ncbi Characterization of the perceived sound of trauma-induced tinnitus in gerbils
    Manuela Nowotny
    Institute of Cell Biology and Neuroscience, Siesmayerstrasse 70A, Goethe University Frankfurt am Main, D 60323 Frankfurt am Main, Germany
    J Acoust Soc Am 130:2827-34. 2011
    ..This supports the theory of lateral inhibition as the physiological basis of tinnitus...
  67. ncbi Development of form and function in peripheral auditory structures of the zebrafish (Danio rerio)
    Dennis M Higgs
    Department of Biology, University of Maryland, College Park, Maryland 20742, USA
    J Acoust Soc Am 113:1145-54. 2003
    ..We propose a model for the development of zebrafish hearing wherein the Weberian ossicles gradually increase the range of frequencies available to the inner ear, much as middle ear development increases frequency range in mammals...
  68. ncbi Auditory cortical responses in hearing subjects and unilateral deaf patients as detected by functional magnetic resonance imaging
    K Scheffler
    MR Center and Biocenter, University of Basel, Switzerland
    Cereb Cortex 8:156-63. 1998
    ..This observation seems to indicate a plasticity or a reorganization of auditory pathways of monaural deaf patients...
  69. ncbi Hearing conservation surgery using the Hybrid-L electrode. Results from the first clinical trial at the Medical University of Hannover
    Thomas Lenarz
    Department of Otolaryngology, Medical University of Hannover, Hannover, Germany
    Audiol Neurootol 14:22-31. 2009
    ..The use of the residual acoustic hearing offers specific advantages, especially for understanding speech in noise and for spatial hearing...
  70. pmc Vigabatrin, a GABA transaminase inhibitor, reversibly eliminates tinnitus in an animal model
    Thomas J Brozoski
    Division of Otolaryngology, Southern Illinois University School of Medicine, 801 N Rutledge St, Rm 3205, P O Box 19629, Springfield, IL 62794 9629, USA
    J Assoc Res Otolaryngol 8:105-18. 2007
    ..Although vigabatrin has serious negative side effects that have prevented its clinical use in the USA, it is nevertheless a potentially useful tool in unraveling tinnitus pathophysiology...
  71. ncbi Forward masking of amplitude modulation: basic characteristics
    Magdalena Wojtczak
    Department of Psychology, University of Minnesota, 75 East River Rd, Minneapolis, Minnesota 55455, USA
    J Acoust Soc Am 118:3198-210. 2005
    ..Overall, the results are consistent with modulation-rate selective neural channels that adapt and recover from the adaptation relatively quickly...
  72. ncbi Effects of cochlear-implant pulse rate and inter-channel timing on channel interactions and thresholds
    John C Middlebrooks
    Kresge Hearing Research Institute, Department of Otorhinolaryngology, University of Michigan Medical School, 1301 E Ann St, Ann Arbor, Michigan 48109 0506, USA
    J Acoust Soc Am 116:452-68. 2004
    ..Thresholds for various paired-pulse stimuli, pulse rates, and pulse-train durations were measured to test possible mechanisms of temporal integration...
  73. ncbi A Speech Intelligibility Index-based approach to predict the speech reception threshold for sentences in fluctuating noise for normal-hearing listeners
    Koenraad S Rhebergen
    Department of Clinical and Experimental Audiology, Academic Medical Center Room D2 223, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Acoust Soc Am 117:2181-92. 2005
    ..For the latter type of maskers, informational masking may play a role...
  74. ncbi Preceding weak noise sharpens the frequency tuning and elevates the response threshold of the mouse inferior collicular neurons through GABAergic inhibition
    Xin Wang
    College of Life Sciences, Central China Normal University, Wuhan, 430079, People s Republic of China
    Brain Res 1167:80-91. 2007
    ..These data indicate that in the real world the ambient noise may improve frequency sensitivity of IC neurons through GABAergic inhibition while inevitably decrease the frequency response range and sensitivity of IC neurons...
  75. pmc Neural correlates and mechanisms of spatial release from masking: single-unit and population responses in the inferior colliculus
    Courtney C Lane
    Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    J Neurophysiol 94:1180-98. 2005
    ..The population thresholds were similar to human behavioral thresholds in both SNR value and shape, indicating that these units may provide a neural substrate for low-frequency SRM...
  76. pmc Effects of temperature on sound production and auditory abilities in the Striped Raphael catfish Platydoras armatulus (Family Doradidae)
    Sandra Papes
    Department of Behavioural Biology, University of Vienna, Vienna, Austria
    PLoS ONE 6:e26479. 2011
    ..This is the first study investigating the influence of temperature on both sound production and on hearing abilities in a fish species, namely the neotropical Striped Raphael catfish Platydoras armatulus...
  77. pmc Standard audiograms for the IEC 60118-15 measurement procedure
    Nikolai Bisgaard
    GN Resound, Ballerup, Denmark
    Trends Amplif 14:113-20. 2010
    ..Therefore, the larger set has been analyzed to provide seven standard audiograms for flat and moderately sloping hearing loss and three standard audiograms for steep hearing loss...
  78. ncbi Seasonal plasticity of peripheral auditory frequency sensitivity
    Joseph A Sisneros
    Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853, USA
    J Neurosci 23:1049-58. 2003
    ....
  79. ncbi Abnormal processing of temporal fine structure in speech for frequencies where absolute thresholds are normal
    Christian Lorenzi
    Equipe Audition, LPP CNRS, Universite Paris Descartes, and DEC, Ecole Normale Superieure, Paris, France
    J Acoust Soc Am 125:27-30. 2009
    ..The results indicate that, for people with hearing loss at medium to high frequencies, the processing of the TFS of speech can be degraded for frequencies where absolute thresholds are within the normal range...
  80. ncbi Sound pressure and particle acceleration audiograms in three marine fish species from the Adriatic Sea
    Lidia Eva Wysocki
    Department of Behavioural Biology, University of Vienna, Althanstrasse 14, A 1090 Vienna, Austria
    J Acoust Soc Am 126:2100-7. 2009
    ..The low auditory thresholds and the large hearing bandwidth of S. umbra indicate that sound pressure may play a role in S. umbra's hearing, even though pronounced connections between the swim bladder and the inner ears are lacking...
  81. ncbi Treatment of mixed hearing losses via implantation of a vibratory transducer on the round window
    Vittorio Colletti
    ENT Department, University of Verona, Verona, Italy
    Int J Audiol 45:600-8. 2006
    ..These results suggest that round window implantation may offer a viable treatment option for individuals with severe mixed hearing losses who have undergone unsuccessful ossiculoplasties...
  82. ncbi Estimating audiometric thresholds using auditory steady-state responses
    Terence W Picton
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Canada
    J Am Acad Audiol 16:140-56. 2005
    ..After 9.8 minutes of recording, the average ASSR thresholds (and standard deviations) were 12.6 +/- 8.7 in the normal subjects, 12.4 +/- 11.9 dB in the normal elderly, and 3.6 +/- 13.5 dB SL in the hearing-impaired subjects...
  83. pmc Detection and rate discrimination of amplitude modulation in electrical hearing
    Monita Chatterjee
    Cochlear Implants and Psychophysics Laboratory, Department of Hearing and Speech Sciences, University of Maryland, College Park, Maryland 20742, USA
    J Acoust Soc Am 130:1567-80. 2011
    ..Overall, results indicated that intensity cues did not play an important role in temporal envelope processing by the average CI listener...
  84. ncbi Phonemic restoration by hearing-impaired listeners with mild to moderate sensorineural hearing loss
    Deniz Baskent
    Starkey Hearing Research Center, Berkeley, CA 94704, USA
    Hear Res 260:54-62. 2010
    ..The overall findings suggest that, in addition to insufficient audibility, degradations in the bottom-up and/or top-down mechanisms as a result of hearing loss may limit or entirely prevent phonemic restoration...
  85. ncbi Accuracy and time efficiency of two ASSR analysis methods using clinical test protocols
    Kathy R Vander Werff
    Department of Communication Sciences and Disorders, Syracuse University, Syracuse, NY 13244, USA
    J Am Acad Audiol 20:433-52. 2009
    ..In addition, there is a need for evaluation of clinical protocols for ASSR testing using these available commercial systems that balance time efficiency and accuracy in estimating threshold...
  86. pmc Solutions to the cocktail party problem in insects: selective filters, spatial release from masking and gain control in tropical crickets
    Arne K D Schmidt
    Department of Zoology, Karl Franzens University, Graz, Styria, Austria
    PLoS ONE 6:e28593. 2011
    ..This is even more a problem in species-rich environments like tropical rainforests, where background noise levels of up to 60 dB SPL have been measured...
  87. pmc Auditory nerve inputs to cochlear nucleus neurons studied with cross-correlation
    E D Young
    Department of Biomedical Engineering and Center for Hearing Sciences, 505 Traylor Building, Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Neuroscience 154:127-38. 2008
    ....
  88. ncbi Transient brain responses predict the temporal dynamics of sound detection in humans
    Ville Mäkinen
    Apperception and Cortical Dynamics, Department of Psychology, University of Helsinki, Helsinki FIN 00014, Finland
    Neuroimage 21:701-6. 2004
    ..Thus, noninvasively measured transient events in the human auditory cortex can be used to predict accurately the temporal course of sound detection and may therefore turn out to be useful in clinical settings...
  89. ncbi Influence of stimulation rate and loudness growth on modulation detection and intensity discrimination in cochlear implant users
    John J Galvin
    Division of Communication and Auditory Neuroscience, House Ear Institute, 2100 West Third Street, Los Angeles, CA 90057, USA
    Hear Res 250:46-54. 2009
    ..In general, high stimulation rates provided no advantage in intensity resolution and a disadvantage in modulation sensitivity...
  90. pmc Amplitude modulation and loudness in cochlear implantees
    Colette M McKay
    Department of Otolaryngology, The University of Melbourne, Melbourne, 3054, Australia
    J Assoc Res Otolaryngol 11:101-11. 2010
    ..We show that several previously published results regarding the effect of carrier rate and added noise on modulation detection could be reinterpreted in the light of these findings...
  91. ncbi Auditory steady-state responses (ASSR): effects of modulation and carrier frequencies
    Charles Petitot
    Laboratoire Neurosciences et Systemes Sensoriels, Lyon, France
    Int J Audiol 44:567-73. 2005
    ..Consequently, when circumstances permit, 40 Hz ASSR testing may be the method of choice (e.g. in the assessment of malingers, who may be tested awake/alert)...
  92. pmc Cochlear-implant high pulse rate and narrow electrode configuration impair transmission of temporal information to the auditory cortex
    John C Middlebrooks
    Department of Otolaryngology Head and Neck Surgery, Kresge Hearing Research Institute, University of Michigan, Ann Arbor, Michigan, USA
    J Neurophysiol 100:92-107. 2008
    ..Results from this animal model suggest explanations for the failure of high pulse rates and/or bipolar electrode configurations to produce hoped-for improvements in speech reception...
  93. ncbi Hearing and morphological specializations of the mojarra (Eucinostomus argenteus)
    Eric Parmentier
    Laboratoire de Morphologie Fonctionnelle et Evolutive, Institut de Chimie, Bât B6, Universite de Liege, B 4000 Liege, Belgium
    J Exp Biol 214:2697-701. 2011
    ..Furthermore, the inclined position of the swimbladder may help the fish to catch their prey more easily, as the swimbladder will be horizontal when they are picking up benthic prey...
  94. pmc Auditory midbrain implant: a review
    Hubert H Lim
    Department of Biomedical Engineering, University of Minnesota, Minneapolis
    Trends Amplif 13:149-80. 2009
    ..Finally, several issues and hypotheses for why current patients obtain limited speech perception along with several feasible solutions for improving AMI implementation are presented...
  95. ncbi An objective measurement of the build-up of auditory streaming and of its modulation by attention
    Sarah K Thompson
    MRC Cognition and Brain Sciences Unit, Cambridge, England
    J Exp Psychol Hum Percept Perform 37:1253-62. 2011
    ..In particular, even though build-up can impair performance in an objective task, participants are unable to prevent this from happening...
  96. ncbi Apical-to-basal gradients in age-related cochlear degeneration and their relationship to "primary" loss of cochlear neurons
    Kevin K Ohlemiller
    Department of Otolaryngology, Washington University, St Louis, Missouri 63110, USA
    J Comp Neurol 479:103-16. 2004
    ..Our findings suggest that these changes share a common triggering influence...
  97. ncbi Neurotoxicological effects of low-dose methylmercury and mercuric chloride in developing offspring mice
    Chun Fa Huang
    School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan
    Toxicol Lett 201:196-204. 2011
    ..The signaling of ROS/Na(+)-K(+)-ATPase/NO(x) plays a crucial role in the underlying mechanism for mercurial compound-induced toxic effects in offspring...
  98. ncbi Auditory midbrain implant: histomorphologic effects of long-term implantation and electric stimulation of a new deep brain stimulation array
    Minoo Lenarz
    Department of Otolaryngology, Hannover Medical University, Hannover, Germany
    Otol Neurotol 28:1045-52. 2007
    ..Chronic implantation and electric stimulation with a human prototype auditory midbrain implant (AMI) array within the inferior colliculus achieves minimal neuronal damage and does not cause any severe complications...
  99. ncbi The impact of chronic suppurative otitis media on children's and teenagers' hearing
    Luciana Fick Silveira Netto
    Ear, Nose and Throat Service, Chronic Otitis Media Ambulatory Care Center, Hospital de Clinicas de Porto Alegre, Brazil
    Int J Pediatr Otorhinolaryngol 73:1751-6. 2009
    ..To verify the relationship between the number of perforated quadrants and the size of the air-bone gap. To compare air-bone gap values between tympanic perforations in posterior quadrants with those in anterior quadrants...
  100. ncbi Acoustical stress and hearing sensitivity in fishes: does the linear threshold shift hypothesis hold water?
    Michael E Smith
    Department of Biology and Center for Comparative and Evolutionary Biology of Hearing, University of Maryland, College Park, MD 20742, USA
    J Exp Biol 207:3591-602. 2004
    ....
  101. ncbi Psychometric functions and temporal integration in electric hearing
    G S Donaldson
    Department of Otolaryngology, University of Minnesota, Minneapolis 55455, USA
    J Acoust Soc Am 101:3706-21. 1997
    ....

Research Grants64

  1. Structure and Function Relations in Middle Ears
    John J Rosowski; Fiscal Year: 2012
    ..structure- function issues: (1) We quantify the contribution of the middle ear to the shape of the auditory threshold curve by (a) comparing middle-ear inputs and outputs to quantify the power transfer efficiency of the middle-..
  2. Potentiation--noise induced hearing loss--acrylonitrile
    Laurence Fechter; Fiscal Year: 2003
    ..will entail the use of distortion product otoacoustic emissions (DPOAE) testing along with assessment of auditory threshold via measurement of the compound action potential (CAP) from the round window...
  3. INTERACTION OF AGE RELATED & NOISE INDUCED HEARING LOSS
    FLINT BOETTCHER; Fiscal Year: 2003
    ..Dr. Boettcher will measure auditory threshold using auditory brainstem responses, and will also, in a subset of animals, obtain measures of histopathology ..
  4. COCHLEAR MECHANISMS OF FREQUENCY MICROSTRUCTURE
    LISA STOVER; Fiscal Year: 2002
    ..questions of the proposal are: 1) Is the cochlear mechanism for frequency microstructure common to both auditory threshold and stimulus frequency OAEs (SFOAEs)? Direct comparison of the microstructure of both threshold and SFOAE ..
  5. FUNCTIONAL EFFECTS OF DEAFNESS AND NEURAL STIMULATION
    BRYAN PFINGST; Fiscal Year: 2005
    ....
  6. Genetic Modulation of Noise Injury to the Cochlear Lateral Wall
    KEVIN OHLEMILLER; Fiscal Year: 2007
    ..The gene, and the processes in which it is involved, may affect the long-term stability of cochlear injury, and the accumulation of injury that may be diagnosed as presbycusis. ..
  7. FEATURES OF STIMULATION IMPORTANT FOR ELECTRICAL HEARING
    BRYAN PFINGST; Fiscal Year: 2003
    ..abstract_text> ..
  8. COCHLEAR VULNERABILITY/REACTIVE OXYGEN SPECIES
    KEVIN OHLEMILLER; Fiscal Year: 2003
    ..Our experiments will establish how well the dynamics of ROS production predict cochlear injury, and whether progressive deafness genes may impair cochlear ROS regulation. ..
  9. Genetic Modulation of Noise Injury to the Cochlear Lateral Wall
    KEVIN OHLEMILLER; Fiscal Year: 2009
    ..The gene, and the processes in which it is involved, may affect the long-term stability of cochlear injury, and the accumulation of injury that may be diagnosed as presbycusis. ..
  10. Acoustic and electrical hearing after Atoh1 treatment
    Bryan E Pfingst; Fiscal Year: 2010
    ....
  11. SPECTRAL CUES FOR SOUND LOCALIZATION
    Bradford May; Fiscal Year: 2008
    ..Consequently, this research will enhance our current understanding of the processes and perceptions that shape directional hearing, speech processing, and compensation for hearing loss in humans. [unreadable] [unreadable]..
  12. Development of Improved Earphone for Hearing Testing
    Robert Margolis; Fiscal Year: 2008
    ..In this project an earphone is being developed that can be used in both automated and manual testing and will significantly increase the efficiency, accuracy, and accessibility. [unreadable] [unreadable] [unreadable]..
  13. A New Approach to Sound Source Identification
    Robert Lutfi; Fiscal Year: 2009
    ..abstract_text> ..
  14. Automated Test of Word Recognition - Phase II
    Robert Margolis; Fiscal Year: 2006
    ..A pilot study will test the method on a Spanish-language speech-recognition test. [unreadable] [unreadable]..
  15. Auditory processing of signals in noise
    Bradford May; Fiscal Year: 2006
    ..A better understanding of the brain's signal processing solutions will lead to improved designs for assistive listening devices that now show poor performance in noisy environments. ..
  16. Channel Interaction in Cochlear Implant Subjects
    JULIE BIERER; Fiscal Year: 2004
    ..The results of these studies could influence the development of future cochlear implant electrodes and speech processing strategies, ideally, leading to improved performance for most cochlear implant subjects. ..
  17. Modulation of age-related changes in the auditory system
    JAMES WILLOTT; Fiscal Year: 2008
    ..The ultimate goal is to develop new approaches for amelioration and treatment ofpresbycusis and other hearing disorders. [unreadable] [unreadable]..
  18. SCREENING MICE FOR AUDITORY & NEUROBEHAVIORAL PHENOTYPES
    JAMES WILLOTT; Fiscal Year: 2002
    ..Johnson. This will be accompanied by development of an easy-to-use software/ hardware package that will integrate all screening techniques in a single, serial protocol for use on individual mice. ..
  19. Auditory Processing of Interaural Envelope Differences
    MARK STELLMACK; Fiscal Year: 2004
    ..This, in turn, will provide clues as to the nature of processing that is most likely performed by the binaural system in extracting interaural envelope differences. ..
  20. Signal Processing in Audition
    Fan Gang Zeng; Fiscal Year: 2009
    ..abstract_text> ..
  21. BINAURAL PROCESSING OF COMPLEX STIMULI
    Leslie Bernstein; Fiscal Year: 2007
    ..abstract_text> ..
  22. Hearing Loss and the Utility of Speech Information
    Benjamin Hornsby; Fiscal Year: 2006
    ..abstract_text> ..
  23. BAEP SCREENING OF NEONATES
    MICHAEL CHURCH; Fiscal Year: 2001
    ..This proposal will address these issues as well. Potentially confounding variables will be gathered and their influence assessed and statistically controlled. Appropriate clinical interventions for mother and infant will be made. ..
  24. COMPLEX AUDITORY PROCESSING WITH COCHLEAR IMPLANTS
    Monita Chatterjee; Fiscal Year: 2010
    ..The clinical relevance of the proposed work is that the findings will contribute to the development of clinical assessment tools and new speech processor designs for future auditory prostheses. ..
  25. Peripherial and Central Mechanisms of Tinnitus Generat
    Carol Bauer; Fiscal Year: 2006
    ..Safe and efficacious therapy for this prevalent and often debilitating problem can only occur with improved understanding of the disorder. ..
  26. SYMPOSIA FOR ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
    JUDY DUBNO; Fiscal Year: 2003
    ..abstract_text> ..
  27. ACOUSTIC RESPONSES OF THE HUMAN COCHLEA AND MIDDLE EAR
    DOUGLAS KEEFE; Fiscal Year: 2008
    ....
  28. OTOREFLECTANCE ASSESSMENT OF MIDDLE-EAR FUNCTIONING
    DOUGLAS KEEFE; Fiscal Year: 2006
    ..Outcomes from Phase II will evaluate whether OR is more accurate than conventional tests to screen and diagnose middle-ear dysfunction in clinical applications of important societal concern. [unreadable] [unreadable]..
  29. Aging and Speech Communication: A Research Conference
    Larry Humes; Fiscal Year: 2007
    ..The proposed conference should lead to further progress in understanding and remedying the speech-communication difficulties of older adults. [unreadable] [unreadable] [unreadable]..
  30. Attentional Modulation of Human Auditory Cortex
    David Woods; Fiscal Year: 2005
    ..Repeated single-subject testing and improved imaging procedures will permit auditory cortical fields to be mapped with unprecedented detail during the processing of simple sounds, syllables and coherent speech. ..
  31. Allocating attention to complex auditory stimuli
    Frederick Gallun; Fiscal Year: 2006
    ..By again employing the dual-task, the attentional resources used by hearing-impaired listeners will be compared with those used by normal-hearing listeners in the same tasks. ..
  32. Complex Sound Segregation by Hearing-Impaired Listeners
    Jennifer Lentz; Fiscal Year: 2004
    ..Future work will be directed toward the cues that encourage good sound segregation, and therefore more normal analysis of spectral shape, to suggest new directions in amplification schemes. ..
  33. Aging and temporal processing: A multi-modality study
    Larry E Humes; Fiscal Year: 2010
    ..Structural equation modeling will be used to examine the correlations between measures and address the degree to which different modalities share a common temporal processing mechanism that is affected by age. ..
  34. Group and Individual Differences in Audition
    Dennis McFadden; Fiscal Year: 2010
    ..If so, theory, diagnosis, treatment, and nosology for ADHD could be affected. ..
  35. COCHLEAR IMPLANT--AUDITORY FUNCTION & SPEECH PERCEPTION
    Michael Dorman; Fiscal Year: 2009
    ..abstract_text> ..
  36. PERCEPTUAL COHERENCE IN LISTENERS WITH HEARING LOSS
    Andrea Pittman; Fiscal Year: 2006
    ..These results may improve our understanding of why hearing-impaired listeners have difficulty perceiving speech in degraded listening environments. [unreadable] [unreadable]..
  37. Aging and Speech Communication: A Research Conference
    Larry Humes; Fiscal Year: 2005
    ..It is hoped that by doing so new Insights into the complex nature of the problem might lead to novel approaches to the improvement of speech communication in older adults. ..
  38. Longitudinal follow-up of hearing in construction workers
    Noah Seixas; Fiscal Year: 2009
    ..abstract_text> ..
  39. AUDITORY ANALYSIS AND SENSORINEURAL HEARING LOSS
    David Nelson; Fiscal Year: 2002
    ..The results of the acoustic biasing experiments may lead to better differential diagnoses of underlying cochlear pathologies in individual patients and thereby point the way to more effective treatment. ..
  40. Temporal Resolution of Cochlear and Auditory Nerve Responses in Older Adults
    Dawn Konrad Martin; Fiscal Year: 2008
    ..Therefore, this research has additional significance in that it may lead to development of clinical tools that will target sources of reduced temporal processing. [unreadable] [unreadable] [unreadable]..
  41. Training and Reinforcement on HPD Use
    Noah Seixas; Fiscal Year: 2008
    ..Results will be presented for scientific publication and developed into guidance and training materials for use by the industry and trades. ..
  42. Perception of Competing Talkers by the Hearing-Impaired
    CAROL MACKERSIE; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  43. DECISION PROCESSES IN DETECTION AND DISCRIMINATION
    Walt Jesteadt; Fiscal Year: 2009
    ..abstract_text> ..
  44. Perception of Sources of Environmental Sounds
    Valeriy Shafiro; Fiscal Year: 2003
    ..The findings of the study will be relevant to cochlear implant design, and will provide an empirical basis for a theory of environmental sound perception. ..
  45. Aging and susceptibility to hearing loss in zebrafish
    Michael Smith; Fiscal Year: 2004
    ..To fulfill these goals, zebrafish will be exposed to specific sound exposures at various ages, and then pathology of the inner ear (via SEM) and hearing thresholds (via auditory brainstem response) will be examined. ..
  46. Hearing in Belgian Waterslager Canaries
    AMANDA LAUER; Fiscal Year: 2004
    ..Thus, the proposed experiments will increase our understanding of the functional consequences of hearing impairment in these birds, and of hearing impairment in general. ..
  47. COMBINATIONS OF MASKING AND SENSORINEURAL HEARING LOSS
    Walt Jesteadt; Fiscal Year: 2001
    ..Hearing loss and masking are clearly not equivalent. Learning more about precisely how they differ will lead to a better understanding of both processes and of how they interact with one another. ..
  48. Imaging gray matter structure in human auditory cortex
    Jennifer Melcher; Fiscal Year: 2004
    ..abstract_text> ..
  49. Mechanical Tuning in Auditory Sensory Hair Bundles
    HAMILTON FARRIS; Fiscal Year: 2004
    ....
  50. Model for prediction of noise-induced hearing loss
    ROGER HAMERNIK; Fiscal Year: 2005
    ..The chinchilla model can be used as a template or a guide for developing a human model possibly from some of the existing human data from which current standards were developed. ..
  51. Implications of OAE Cochlear Source Contribution
    Tiffany Johnson; Fiscal Year: 2006
    ..4) The role of fine structure (thought to arise from the complex summation of distortion- and reflection-source energy for DPOAEs) in prediction and diagnostic errors will be evaluated. ..
  52. Quantifying the Role of Ca2+ in Mechanotransduction
    HAMILTON FARRIS; Fiscal Year: 2005
    ..abstract_text> ..
  53. Effects of High-Rate Pulse Trains on Discrimination
    Christina Runge Samuelson; Fiscal Year: 2006
    ..The data analyses will focus on comparisons between discrimination ability, with and without high-rate pulse trains. ..
  54. Early Development of Auditory Temporal Processing
    Lincoln Gray; Fiscal Year: 2004
    ....
  55. Neural Bases of Auditory Processing Disorders in Adults
    Patrick Wong; Fiscal Year: 2007
    ..2) Whether it is feasible to use MRI to identify neurophysiologic anomalies in APD adults. If so, whether APD is associated with a collection of unifying or diverse neurophysiologic anomalies. [unreadable] [unreadable]..
  56. Acquisition of Mandarin Tones: A Cross-Sectional Study
    Patrick Wong; Fiscal Year: 2007
    ..For the rehabilitation of adults, it is especially important to understand how adults learn. [unreadable] [unreadable] [unreadable]..
  57. Otitis Media Impact on the Inner Ear
    Dennis Trune; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  58. CLINICAL MEASURES OF AUDITORY LINEAR/NONLINEAR PROCESSES
    MARK CHERTOFF; Fiscal Year: 2004
    ..abstract_text> ..
  59. Infant hearing for modulated tones
    Barbara Cone Wesson; Fiscal Year: 2003
    ..This research will also result in methods for assessing threshold sensitivity and sound discrimination in infants that can be applied to those at risk for hearing loss or other auditory dysfunction. ..
  60. The Mouse as a Tool for Ear Research
    Kenneth Johnson; Fiscal Year: 2003
    ..abstract_text> ..