generalization psychology


Summary: The phenomenon of an organism's responding to all situations similar to one in which it has been conditioned.

Top Publications

  1. ncbi [Experimental complex partial seizure and its possible clinical application]
    T Tanaka
    Department of Neurosurgery, Asahikawa Medical College
    No To Hattatsu 22:121-5. 1990
  2. ncbi Reproducibility of histopathologic diagnosis and classification of non-melanocytic skin cancer: a panel exercise in the framework of the multicenter southern European study HELIOS
    J Wechsler
    Service d'Anatomie et Cytologie Pathologiques, Hĵpital Henry Mondor, , France
    Tumori 87:95-100. 2001
  3. ncbi [Sturge-Weber syndrome: differential diagnosis of neurocysticercosis]
    A C Stokes
    , , , Curitiba, Brasil
    Rev Neurol 30:41-4. 2000
  4. ncbi Assessment of the discriminative stimulus effects of the D3 dopamine antagonist PNU-99194A in rats: comparison with psychomotor stimulants
    L E Baker
    Department of Psychology, Western Michigan University, Kalamazoo 49008, USA
    Behav Pharmacol 8:243-52. 1997
  5. ncbi Discriminative stimulus properties of nicotine at low doses: the effects of caffeine preload
    T Duka
    University of Sussex, Brighton, UK
    Behav Pharmacol 9:219-29. 1998
  6. ncbi Selectivity in the generalization profile in baboons trained to discriminate lorazepam: benzodiazepines, barbiturates and other sedative/anxiolytics
    N A Ator
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    J Pharmacol Exp Ther 282:1442-57. 1997
  7. ncbi [Diagnosis and drug treatment in hyperactive children]
    H Hara
    National Institute of Mental Health, National Center of Neurology and Psychiatry, Chiba
    No To Hattatsu 26:169-74. 1994
  8. ncbi [Intercritical SPECT in drug-resistant partial epilepsy with normal MRI: a study of 33 cases]
    J A Vidal
    Servicio de Neurologia, Hospital General de Asturias, Oviedo,
    Rev Neurol 25:48-55. 1997
  9. ncbi The effects of sigma, PCP, and opiate receptor ligands in rats trained with ibogaine as a discriminative stimulus
    S Helsley
    Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14214 3000, USA
    Pharmacol Biochem Behav 59:495-503. 1998
  10. ncbi Four-choice drug discrimination in pigeons
    M Li
    Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Behav Pharmacol 12:621-8. 2001

Detail Information

Publications245 found, 100 shown here

  1. ncbi [Experimental complex partial seizure and its possible clinical application]
    T Tanaka
    Department of Neurosurgery, Asahikawa Medical College
    No To Hattatsu 22:121-5. 1990
    ..4) Autoradiography of the calcium suggested that one of the causes of hippocampal degeneration in intractable complex partial seizures should be a consequence of calcium influx into pyramidal cells during repeated limbic seizures...
  2. ncbi Reproducibility of histopathologic diagnosis and classification of non-melanocytic skin cancer: a panel exercise in the framework of the multicenter southern European study HELIOS
    J Wechsler
    Service d'Anatomie et Cytologie Pathologiques, Hĵpital Henry Mondor, , France
    Tumori 87:95-100. 2001
    ..Routine histologic diagnoses of cutaneous carcinoma showed a high degree of reliability with reference to the assessment of malignancy and the distinction between basal and squamous cell carcinoma morphotypes...
  3. ncbi [Sturge-Weber syndrome: differential diagnosis of neurocysticercosis]
    A C Stokes
    , , , Curitiba, Brasil
    Rev Neurol 30:41-4. 2000
    ..Following physical examination and complementary tests the diagnosis of Sturge-Weber syndrome was made. CONCLUSION: We emphasize the importance of the diagnosis of Sturge-Weber syndrome, its clinical picture and treatment...
  4. ncbi Assessment of the discriminative stimulus effects of the D3 dopamine antagonist PNU-99194A in rats: comparison with psychomotor stimulants
    L E Baker
    Department of Psychology, Western Michigan University, Kalamazoo 49008, USA
    Behav Pharmacol 8:243-52. 1997
    ..Given the unique behavioral profile of D3 receptor antagonists, the potential utility of these agents as adjunctive treatments for psychostimulant abuse is discussed...
  5. ncbi Discriminative stimulus properties of nicotine at low doses: the effects of caffeine preload
    T Duka
    University of Sussex, Brighton, UK
    Behav Pharmacol 9:219-29. 1998
    ..These data are discussed in terms of interoceptive nicotine cues and their importance at different doses and after caffeine preload...
  6. ncbi Selectivity in the generalization profile in baboons trained to discriminate lorazepam: benzodiazepines, barbiturates and other sedative/anxiolytics
    N A Ator
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    J Pharmacol Exp Ther 282:1442-57. 1997
  7. ncbi [Diagnosis and drug treatment in hyperactive children]
    H Hara
    National Institute of Mental Health, National Center of Neurology and Psychiatry, Chiba
    No To Hattatsu 26:169-74. 1994
    ..The antidepressant proved very effective to his hyperactivity and temper tantrum, but not to his enuresis...
  8. ncbi [Intercritical SPECT in drug-resistant partial epilepsy with normal MRI: a study of 33 cases]
    J A Vidal
    Servicio de Neurologia, Hospital General de Asturias, Oviedo,
    Rev Neurol 25:48-55. 1997
    ..05). This would seem to suggest that the anomalies found were more a result of the cause of the epilepsy than of the repetition of crises. SPECT should be included in the diagnostic algorithms of focal epilepsy with normal...
  9. ncbi The effects of sigma, PCP, and opiate receptor ligands in rats trained with ibogaine as a discriminative stimulus
    S Helsley
    Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14214 3000, USA
    Pharmacol Biochem Behav 59:495-503. 1998
    ..Thus, the present study offers evidence that unlike NMDA receptors, both sigma2 and opiate receptors may be involved in the ibogaine discriminative stimulus...
  10. ncbi Four-choice drug discrimination in pigeons
    M Li
    Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Behav Pharmacol 12:621-8. 2001
    ..The four-choice procedure offers some important advantages for studying the discriminative stimulus effects of drugs that interact with multiple receptor subtypes and for studying drug mixtures...
  11. ncbi Acquisition of nicotine discrimination and discriminative stimulus effects of nicotine in rats chronically exposed to caffeine
    M Gasior
    Preclinical Pharmacology Laboratory, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA
    J Pharmacol Exp Ther 288:1053-73. 1999
  12. ncbi The effect of vitamin-mineral supplementation on juvenile delinquency among American schoolchildren: a randomized, double-blind placebo-controlled trial
    S J Schoenthaler
    Department of Sociology and Criminal Justice, California State University, Stanislaus, Turlock 95380, USA
    J Altern Complement Med 6:7-17. 2000
    ..However, generalization could not be made to typical schoolchildren without a controlled trial examining violence and antisocial behavior in public schools...
  13. ncbi [Early presentation of crises and the development of epilepsy in cerebral intra-parenchymatous hemorrhage]
    I Pérez López-Fraile
    Servicio de Neurologia, Hospital Miguel Servet, Zaragoza, Espana
    Rev Neurol 28:305-9. 1999
    ..In those with crises there was a predominance of bilobular involvement with participation of the parietal lobe and extension of the hematoma or oedema to the cerebral cortex...
  14. ncbi Sleep apnea syndrome in the elderly
    B Fleury
    Laboratoire du Sommeil, , Paris
    Sleep 15:S39-41. 1992
    ..abstract truncated at 250 words)..
  15. ncbi Adoption of fluoride-based caries preventive innovations in a public dental service
    O Haugejorden
    Department of Community Dentistry, University of Bergen, Norway
    Community Dent Oral Epidemiol 16:5-10. 1988
    ..Consequently, there is a need for more and larger scale comparative analytical studies to increase our understanding of diffusion and adoption of innovations in dentistry...
  16. ncbi Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee
    A J Mangram
    Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Am J Infect Control 27:97-132; quiz 133-4; discussion 96. 1999
    ..g., laparoscopic cholecystectomy). Recommend specific antiseptic agents for patient preoperative skin preparations or for healthcare worker hand/forearm antisepsis. Hospitals should choose from products recommended for these activitie..
  17. ncbi Developmental alterations in auditory arousal from sleep in healthy and virus-infected cats
    L A Toth
    Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tenn. 38105, USA
    Sleep 21:143-52. 1998
    ..The generalization of these observations to other arousing stimuli, such as hypoxia or hypercapnia, and possible implications for the pathogenesis of sudden infant death syndrome remain to be determined...
  18. ncbi Oxidative stress in the molecular mechanism of pathogenesis at different diseased states of organism in clinics and experiment
    Konstantin G Karageuzyan
    Institute of Molecular Biology, National Academy of Sciences of the Republic of Armenia, 7, Hasratyan Str, Yerevan 375014, Republic of Armenia
    Curr Drug Targets Inflamm Allergy 4:85-98. 2005
    ..These data serve a sound affirmation for protectory function of STS, detailed revelation of molecular properties of pathogenesis of the studied intoxication to which a part of our clinical and experimental studies at present is devoted...
  19. ncbi Generalization of a habituated feeding deterrent response to unrelated antifeedants following prolonged exposure in a generalist herbivore, Trichoplusia ni
    Yasmin Akhtar
    Faculty of Agricultural Sciences, University of British Columbia Vancouver, BC, Canada V6T 1Z4
    J Chem Ecol 30:1349-62. 2004
    ..The implications of such behavioral plasticity in herbivorous insects for the use of antifeedants as crop protectants or for host plant shifts is discussed...
  20. ncbi Perception of pitch by goldfish
    Richard R Fay
    Parmly Hearing Institute, Department of Psychology, Loyola University, Chicago, IL 60626, USA
    Hear Res 205:7-20. 2005
  21. ncbi [Mesial temporal sclerosis (II): clinical features and complementary studies]
    P J Serrano Castro
    , , ,
    Rev Neurol 26:592-7. 1998
    ..Results of the non-invasive tests currently available make invasive tests unnecessary in the preoperative guidelines for these patients...
  22. ncbi [Benign partial convulsions in adolescence]
    R Caraballo
    , , Buenos Aires, Argentina
    Rev Neurol 28:669-71. 1999
    ..Neurological examination, EEG between crises and neuro-radiological studies were normal...
  23. ncbi Asymmetric generalization between the discriminative stimulus effects of nicotine and cocaine
    R I Desai
    School of Psychology, University of Birmingham, Edgbaston, UK
    Behav Pharmacol 10:647-56. 1999
  24. ncbi Discriminative stimulus properties of amphetamine in a conditioned taste aversion paradigm
    F M Herrera
    Escuela Nacional de Estudios Profesionales, Iztacala, Mexico, DF
    Behav Pharmacol 8:458-64. 1997
    ..Taken together, the present results suggest the usefulness of the conditioned taste aversion procedure to train subjects in drug discrimination...
  25. ncbi Do beta-blockers really increase peripheral vascular resistance? Review of the literature and new observations under basal conditions
    A J Man in't Veld
    Department of Internal Medicine, Erasmus University Rotterdam, The Netherlands
    Am J Hypertens 1:91-6. 1988
    ..Thus, like all other antihypertensive agents, beta-blockers also lower blood pressure through interference with a vasoconstrictor mechanism...
  26. ncbi [Long latency auditory evoked potentials in schoolchildren and adolescents with epilepsy]
    Małgorzata Zgorzalewicz
    Katedra Profilaktyki Zdrowotnej AM, Pracownia Elektrodiagnostyki Medycznej, 60 355 Poznan, Ul Przybyszewskiego 49
    Przegl Lek 63:8-13. 2006
    ..They are an objective and non-invasive procedure and a recommended standard for clinical evaluation of mental processing...
  27. ncbi Common discriminative stimulus properties in rats of muscarinic antagonists, clozapine and the D3 preferring antagonist PNU-99194a: an analysis of possible mechanisms
    A J Goudie
    Psychology Department, Liverpool University, UK
    Behav Pharmacol 12:303-15. 2001
    ..Some preclinical data are suggestive of such effects of PNU-99194A...
  28. ncbi Reinforcement schedule effects in rats trained to discriminate 3,4-methylenedioxymethamphetamine (MDMA) or cocaine
    Daniel Kueh
    Department of Biological Sciences, Western Michigan University, Kalamazoo, MI 49008, USA
    Psychopharmacology (Berl) 189:447-57. 2007
    ..One possible reason for discrepant results may be the use of different reinforcement schedules during discrimination training...
  29. ncbi [Cranioencephalic cutaneous angiofibromatosis]
    M Nieto
    , , Sevilla,
    Rev Neurol 24:1267-71. 1996
    ..We discuss whether the presentation of this case of encephalocraneo-cutaneous angiofibromatosis is a new phenotype of tuberose sclerosis or a new neurocutaneous syndrome...
  30. ncbi Does the milk of Callitrichid monkeys differ from that of larger anthropoids?
    Michael L Power
    Nutrition Laboratory, Department of Conservation Biology, National Zoological Park, Smithsonian Institution, Washington, DC 20008, USA
    Am J Primatol 56:117-27. 2002
  31. pmc Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors
    Lisa M Bateman
    Clinical Neurophysiology, UCDMC, Sacramento, CA 95817, USA
    Brain 131:3239-45. 2008
    ..Oxygen desaturations are accompanied by increases in ETCO2, supporting the assumption that ictal oxygen desaturation is a consequence of hypoventilation. Ictal hypoxemia and hypercapnia may contribute to SUDEP...
  32. ncbi Habituation in the crab Chasmagnathus granulatus: effect of morphine and naloxone
    D Brunner
    Laboratorio de Fisiologia del Comportamiento Animal, Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina
    J Comp Physiol A 162:687-94. 1988
    ..The potential value of the response habituation as a model for studying both habituation dynamics and the mechanisms that subserve it, and also for elucidating the effects of opiates on this memory process, is discussed...
  33. ncbi [Familial benign partial epilepsy of early infancy]
    B Carrera
    , Hospital Virgen del Camino, Pamplona,
    Rev Neurol 26:1013-4. 1998
    ..CONCLUSION: We consider that this syndrome should be included in the International Classification of Epilepsy and Epileptic Syndromes as benign familial idiopathic partial epilepsy...
  34. ncbi Self-regulation of slow cortical potentials: a new treatment for children with attention-deficit/hyperactivity disorder
    Ute Strehl
    Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Gartenstrasse 29, 72074 Tubingen, Germany
    Pediatrics 118:e1530-40. 2006
    ..Electroencephalographic data from the training and the 6-month follow-up are reported, as are changes in behavior and cognition...
  35. ncbi [Clinical applications and the effect of mexiletine on refractory epilepsies]
    H Enoki
    Department of Child Neurology, Okayama University Medical School
    No To Hattatsu 32:29-34. 2000
    ..Follow-up for more than 3 months showed seizures to be lessened in 2 patients. Mexiletine is useful for the treatment of refractory epilepsies, especially SPE...
  36. ncbi Differentiating benzodiazepine- and barbiturate-like discriminative stimulus effects of lorazepam, diazepam, pentobarbital, imidazenil and zaleplon in two- versus three-lever procedures
    N A Ator
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Behav Pharmacol 11:1-14. 2000
    ..These results show that when the opportunity for finer differentiation of discriminative effects of GABAergic drugs is provided, a generalization profile more in line with differential in-vitro profiles can be revealed...
  37. ncbi Nalorphine's ability to substitute for morphine in a drug discrimination procedure is a function of training dose
    S D Grabus
    Department of Psychology, American University, Washington, DC 20016, USA
    Pharmacol Biochem Behav 63:481-8. 1999
  38. ncbi The application of differential outcomes to a cocaine--saline discrimination procedure
    T B Morgan
    Department of Psychology, Western Michigan University, Kalamazoo 49008, USA
    Behav Pharmacol 8:31-6. 1997
    ..Similar cocaine dose-response functions were observed with the differential outcome group and the control group and there was not a statistically significant effect of differential outcomes on the cocaine generalization curve...
  39. ncbi Phytoplankton blooms and fish recruitment rate: effects of spatial distribution
    V N Biktashev
    Department of Applied Mathematics, University of Leeds, Leeds LS2 9JT, UK
    Bull Math Biol 66:233-59. 2004
    ..However, in this case, recruitment is very low...
  40. ncbi Levetiracetam: a review of its use in epilepsy
    Katherine A Lyseng-Williamson
    Adis, a Wolters Kluwer Business, Auckland, New Zealand
    Drugs 71:489-514. 2011
    ..Levetiracetam is not associated with cognitive impairment or drug-induced weight gain, but has been associated with behavioural adverse effects in some patients...
  41. ncbi The generalization of an olfactory-based conditioned response reveals unique but overlapping odour representations in the moth Manduca sexta
    K C Daly
    Department of Entomology, Ohio State University, Columbus, OH 43210 1220, USA
    J Exp Biol 204:3085-95. 2001
    ..These data are consistent with a cross-fiber coding scheme in which odours are coded by spatio-temporally overlapping sets of neurons, both in the periphery and in the antennal lobes...
  42. ncbi Sensitization to apomorphine in pigeons is due to conditioning, subject to generalization but resistant to extinction
    A M Godoy
    Allgemeine Psychologie, , Germany
    Behav Pharmacol 10:367-78. 1999
    ..These results are related to findings and arguments concerning the sensitization to psychostimulant drugs in mammals...
  43. ncbi [Benign infantile familial convulsions]
    R Caraballo
    Servicio de Neurologia, , Garrahan, Buenos Aires, Argentina
    Rev Neurol 25:682-4. 1997
  44. ncbi Perception of the periodicity strength of complex sounds by the chinchilla
    William P Shofner
    Parmly Hearing Institute, Loyola University Chicago, 6525 N Sheridan Rd, IL 60626, USA
    Hear Res 173:69-81. 2002
  45. pmc Would physicians override a do-not-resuscitate order when a cardiac arrest is iatrogenic?
    D J Casarett
    University of Pennsylvania, Philadelphia, USA
    J Gen Intern Med 14:35-8. 1999
    ..To assess whether physicians would be more likely to override a do-not-resuscitate (DNR) order when a hypothetical cardiac arrest is iatrogenic...
  46. ncbi Antagonism of metabotropic glutamate receptor 4 receptors by (RS)-alpha-cyclopropyl-4-phosphonophenylglycine alters the taste of amino acids in rats
    B K Eschle
    Department of Biology and Vermont Chemical Senses Group, 109 Carrigan Drive, University of Vermont, Burlington, VT 05405, USA
    Neuroscience 163:1292-301. 2009
    ..These findings suggest that multiple receptors are involved in amino acid taste and that taste-mGluR4 receptors contribute to the taste of MSG and at least some l-amino acids...
  47. pmc Discovery of dominant and dormant genes from expression data using a novel generalization of SNR for multi-class problems
    Yu Shuen Tsai
    Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan
    BMC Bioinformatics 9:425. 2008
    ..Using information from the literature we have shown that the GDI based method can identify dominant and dormant genes that play significant roles in cancer biology. These biomarkers are also used to design diagnostic prediction systems...
  48. ncbi [Multiple sclerosis as a cause of partial complex epilepsy]
    V Bertol
    Servicio de Neurologia, Hospital Miguel Servet, Zaragoza,
    Rev Neurol 25:78-9. 1997
    ..In both cases demyelinating lesion was located in the temporal lobe, agreeing with EEG anomaly and seizures type...
  49. ncbi Role of 5-HT1B, 5-HT2A and 5-HT2C receptors in the generalization of 5-HT receptor agonists to the ethanol cue in the rat
    S Maurel
    CNS Research, Bayer AG, Cologne, Germany
    Behav Pharmacol 9:337-43. 1998
  50. ncbi [Teratoma in the cerebellar hemisphere of an infant]
    M Aibe
    Department of Pediatrics, Kyushu Rosai Hospital, Kitakyushu, Fukuoka
    No To Hattatsu 33:45-8. 2001
    ..Intracranial teratomas have a predilection for supratentorial and midline sites. They are the most common in the neonatal period. We presented a very rare case of teratoma in the cerebellar hemisphere of an infant...
  51. ncbi Age structure, the life course and "aged heterogeneity": prospects for research and theory
    D Dannefer
    Graduate School of Education and Human Development, University of Rochester, NY 14627
    Compr Gerontol B 2:1-10. 1988
    ..Finally, we consider the possible influence of age strata differences in intrastratum variability upon other aspects of social structure and upon individual aging...
  52. ncbi Discriminative stimulus properties of the atypical antipsychotic clozapine and the typical antipsychotic chlorpromazine in a three-choice drug discrimination procedure in rats
    Joseph H Porter
    Department of Psychology, Virginia Commonwealth University, PO Box 842018, 808 West Franklin Street, Richmond, VA 23284 2018, USA
    Psychopharmacology (Berl) 178:67-77. 2005
    ..The atypical antipsychotic drug (APD) clozapine elicits a robust discriminative cue that is generally selective for other atypical APDS in two-choice drug discrimination (DD) procedures...
  53. ncbi Frequency of stuttering during challenging and supportive virtual reality job interviews
    Shelley B Brundage
    The George Washington University, Speech and Hearing Science Department, 1922 F Street NW, Suite 400, Washington, DC 20052, United States
    J Fluency Disord 31:325-39. 2006
    ..Participants' subjective reports of the VR experience indicate reactions similar to those they report experiencing in the real world. Possible implications for the use of VR in the assessment and treatment of stuttering are discussed...
  54. pmc Overgeneralization of conditioned fear as a pathogenic marker of panic disorder
    Shmuel Lissek
    Mood and Anxiety Disorders Program, NIMH Intramural Research Program, Bethesda, MD, USA
    Am J Psychiatry 167:47-55. 2010
    ..The authors conducted a laboratory-based assessment of this potential correlate of panic disorder by testing the degree to which panic patients and healthy subjects manifest generalization of conditioned fear...
  55. ncbi The natural history of sex-linked recessive dystonia parkinsonism of Panay, Philippines (XDP)
    Lillian V Lee
    Office of the Executive Director, Child Neuroscience Division, Department of Health, Philippine Children s Medical Center, Quezon Avenue, Quezon City, Philippines
    Parkinsonism Relat Disord 9:29-38. 2002
    ..Genetic studies have located the affected gene (DYT3) to Xq13.1. Nemeth's group has mapped the XDP gene to a <350 kb locus in the DXS 7117-DX 559 region. To date, no treatment has been proven consistently effective...
  56. ncbi [Influence of epilepsy-related factors on scholastic achievement in an epileptic child]
    E M Pestana
    Servicio de Neurologia Infantil, Instituto de Neurologia y Neurocirugia, Ciudad de La Habana, Cuba
    Rev Neurol 25:44-7. 1997
  57. ncbi [A case of neonatal tuberous sclerosis with large calcified lesions in the brain parenchyma]
    K Shimizu
    Department of Pediatrics, Kikukawa General Hospital, Shizuoka
    No To Hattatsu 24:575-80. 1992
    ..The neonate with tuberous sclerosis should be carefully evaluated because of the atypical appearance of MRI in rare cases...
  58. ncbi Discriminative stimulus effects of two doses of fentanyl in rats: pharmacological selectivity and effect of training dose on agonist and antagonist effects of mu opioids
    L Zhang
    Department of Psychology, Wayne State University, 71 West Warren Avenue, Detroit, MI 48202, USA
    Psychopharmacology (Berl) 148:136-45. 2000
    ..Discriminative stimulus effects of mu opioids vary systematically as a function of training dose. Differences among training doses may arise from multiple mechanisms...
  59. pmc Oral health with fixed appliances orthodontics
    Wilhelm Frank
    ARWIG, Gesundheitssystemberatung GmbH, Wien, Osterreich
    GMS Health Technol Assess 4:Doc02. 2008
    ..Orthodontics deserves a well discussed scientific position to prove the enormous individual success and to demonstrate the effectiveness of the developed treatments...
  60. ncbi [Epilepsy and arteriovenous malformations]
    M Kawasaki
    , , Curitiba, , Brasil
    Rev Neurol 28:1040-2. 1999
    ..CONCLUSIONS: We observed that cortical and not cortical arteriovenous malformation associates to epileptic seizures and in the cases in which it is possible, the surgical treatment favors the control of the seizures...
  61. ncbi Individual differences in response to novelty, amphetamine-induced activity and drug discrimination in rats
    R A Bevins
    Department of Psychology, University of Nebraska Lincoln 68588 0308, USA
    Behav Pharmacol 8:113-23. 1997
    ..The relationships are discussed in terms of identifying processes common to the screens (e.g. stress and reward)...
  62. ncbi Selectivity in generalization to GABAergic drugs in midazolam-trained baboons
    Nancy A Ator
    Department of Psychiatry and Behavioral Sciences, Behavioral Biology Research Center, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Suite 3000, Johns Hopkins Bayview Campus, Baltimore, MD 21224, USA
    Pharmacol Biochem Behav 75:435-45. 2003
    ..However, to date, positive modulation of GABA through the barbiturate site is not generally sufficient for this effect in nonhuman primates and pigeons although it is in rodents...
  63. ncbi A comparison of the stimulus effects of codeine in rhesus monkeys under the contingencies of a two lever discrimination task and a cross self-administration paradigm: tests of generalization to pentazocine, buprenorphine, tilidine, and different doses of
    F Hoffmeister
    Bayer AG, Geschäftsbereich Pharma EP, Wuppertal, Federal Republic of Germany
    Psychopharmacology (Berl) 94:315-20. 1988
    ..It is concluded that the cross self-administration procedure is more sensitive for the assessment of opioid-like stimulus properties of drugs than the two lever discrimination task...
  64. ncbi Long-term outcomes of pediatric ocular myasthenia gravis
    Steve Ortiz
    Department of Ophthalmology, Vision Center at Childrens Hospital Los Angeles, University of Southern California, Keck School of Medicine, Los Angeles, California, USA
    Ophthalmology 115:1245-1248.e1. 2008
    ..To review the presenting signs, therapeutic interventions, and clinical outcomes of purely ocular myasthenia gravis in a preadolescent population treated primarily with pyridostigmine bromide...
  65. ncbi Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats
    Andrew J Goudie
    Psychopharmacology, School of Psychology, Liverpool University, Liverpool, UK
    J Psychopharmacol 21:179-90. 2007
  66. ncbi Metabolic and functional mapping of the neural network subserving inferior collicular seizure generalization
    T J McCown
    Department of Psychiatry, University of North Carolina at Chapel Hill 27599, USA
    Brain Res 701:117-28. 1995
    ..Thus, specific forebrain sites form a widespread neural network that mediates the generalization of seizure activity from the inferior collicular cortex into the forebrain...
  67. pmc Cortical and subcortical networks in human secondarily generalized tonic-clonic seizures
    H Blumenfeld
    Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8018, USA
    Brain 132:999-1012. 2009
    ..Understanding the networks involved in generalized tonic-clonic seizures can provide insights into mechanisms of behavioural changes, and may elucidate targets for improved therapies...
  68. ncbi Antagonism of a (+)N-allylnormetazocine stimulus by (-)PPAP and several structurally related analogs
    R A Glennon
    Department of Medicinal Chemistry, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0540
    Pharmacol Biochem Behav 45:865-9. 1993
    ..They do, however, demonstrate that sigma-ligands with little to no affinity for PCP receptors are capable of antagonizing the (+)NANM stimulus...
  69. ncbi Response generalization in apraxia of speech treatments: taking another look
    K J Ballard
    Department of Speech and Hearing Sciences, Indiana University, Bloomington 47405, USA
    J Commun Disord 34:3-20. 2001
    ..4) An understanding of how theories of speech motor control might guide selection of behaviors to test treatment effects and response generalization...
  70. ncbi Subtle differences in the discriminative stimulus effects of cocaine and GBR-12909
    S R Tella
    Department of Pharmacology, Georgetown University School of Medicine, Washington, DC 20007, USA
    Prog Neuropsychopharmacol Biol Psychiatry 25:639-56. 2001
    ..The findings suggest similarities as well as subtle, but important, differences between the discriminative stimulus effects of cocaine and the dopamine uptake inhibitors, GBR-12909 and GBR12935...
  71. ncbi Generalization of D-, L- and DL-chlorpheniramine and zolantidine to the discriminative stimulus effects of cocaine and methamphetamine
    T Suzuki
    Department of Pharmacology, School of Pharmacy, Hoshi University, Tokyo, Japan
    Behav Pharmacol 8:718-24. 1997
    ..These findings imply that although the dopaminergic system plays an important role in the discriminative stimulus effects of both cocaine and methamphetamine, there may be differences between their effects...
  72. ncbi Increased secondary generalization of partial seizures after temporal lobectomy
    T R Henry
    Department of Neurology, School of Medicine, Emory University, Atlanta, GA 30322, USA
    Neurology 55:1812-7. 2000
  73. pmc Taste perception of monosodium glutamate and inosine monophosphate by 129P3/J and C57BL/6ByJ mice
    Yuko Murata
    Monell Chemical Senses Center, Philadelphia, PA, 19104 3308, USA
    Physiol Behav 98:481-8. 2009
    ..The amiloride-sensitive salt taste component is more prevalent in MSG than in IMP taste, and in B6 compared with 129 mice...
  74. ncbi Declines in stimulated striatal dopamine release over the first 32 h following microdialysis probe insertion: generalization across releasing mechanisms
    R R Holson
    Department of Psychology, New Mexico Tech, Socorro, NM 87801, USA
    Brain Res 808:182-9. 1998
    ..We conclude that there is a general decline over time post-probe implantation in the ability of the striatal dopamine system to release dopamine, and perhaps to increase dopamine synthesis, in response to pharmacological challenges...
  75. ncbi Delta opioid discrimination learning in the rat: assessment with the selective delta agonist SNC80
    Glenn W Stevenson
    Psychopharmacology Laboratory, Department of Psychology, American University, Washington, DC 20016, USA
    Pharmacol Biochem Behav 71:283-92. 2002
  76. ncbi Using stacked generalization to predict membrane protein types based on pseudo-amino acid composition
    Shuang Quan Wang
    Institute of Image Processing and Pattern Recognition, Shanghai Jiaotong University, Shanghai 200240, China
    J Theor Biol 242:941-6. 2006
    ..The stacked generalization classifier is available as a web-server named "SG-MPt_Pred" at:
  77. pmc The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization
    Angela M Batman
    Department of Pharmacology and Toxicology, Virginia Commonwealth University, 410 N 12th Street, Richmond, VA 23298, USA
    Eur J Pharmacol 648:127-32. 2010
  78. pmc Classification across gene expression microarray studies
    Andreas Buness
    German Cancer Research Center DKFZ, Department of Molecular Genome Analysis, 69120 Heidelberg, Germany
    BMC Bioinformatics 10:453. 2009
    ..Our derived version (DV) aims to improve the robustness of the intrinsic invariance of kTSP with respect to technologies and preprocessing...
  79. ncbi Dissociation between medial temporal lobe and basal ganglia memory systems in schizophrenia
    Szabolcs Keri
    Department of Psychiatry, University of Szeged, Semmelweis u 6, Szeged, H 6725, Hungary
    Schizophr Res 77:321-8. 2005
    ..High-dose first generation antipsychotics may disrupt BG-dependent learning by blocking dopaminergic neurotransmission in the nigro-stiratal system...
  80. ncbi Discriminative stimulus properties of the atypical neuroleptic clozapine in rats: tests with subtype selective receptor ligands
    A J Goudie
    Psychology Department, Liverpool University, UK
    Behav Pharmacol 9:699-710. 1998
  81. ncbi Roles of novelty, generalization, and postingestive feedback in the recognition of foods by lambs
    J J Villalba
    Department of Rangeland Resources, Utah State University, Logan 84322 5230, USA
    J Anim Sci 78:3060-9. 2000
    ..Once generalization occurred, postingestive feedback from nutrients and toxins calibrated preference according to the food's utility...
  82. ncbi [Two cases of post-encephalitic epilepsy characterized by auditory cognitive dysfunction; comparison with "a peculiar type of post-encephalitic/encephalopathic epilepsy"]
    T Yamamoto
    Division of Child Neurology, Tottori University Faculty of Medicine
    No To Hattatsu 27:291-6. 1995
    ..The presented two cases were characterized by auditory cognitive dysfunction and intractable epilepsy with secondary generalization...
  83. pmc Increasing CREB in the auditory thalamus enhances memory and generalization of auditory conditioned fear
    Jin Hee Han
    Program in Neurosciences and Mental Health, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    Learn Mem 15:443-53. 2008
    ..Not only do these findings refine our knowledge of the circuitry underlying fear memory but they also provide novel insights into the neural substrates that govern the degree to which acquired fear of a tone generalizes to other tones...
  84. ncbi Perception of two-tone complexes by the goldfish (Carassius auratus)
    R R Fay
    Department of Psychology and Parmly Hearing Institute, Loyola University Chicago, IL 60626, USA
    Hear Res 120:17-24. 1998
    ..Thus, goldfish behaved as if they had acquired information about both temporal modulation and the frequency location of the tone components. These perceptual behaviors appear to be shared with humans and other vertebrates...
  85. ncbi The paradox of 5-methoxy-N,N-dimethyltryptamine: an indoleamine hallucinogen that induces stimulus control via 5-HT1A receptors
    J C Winter
    Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Pharmacol Biochem Behav 65:75-82. 2000
  86. ncbi Generalization of clozapine as compared to other antipsychotic agents to a discriminative stimulus elicited by the serotonin (5-HT)2A antagonist, MDL100,907
    A Dekeyne
    Psychopharmacology Department, Institut de Recherches Servier, Centre de Recherches de Croissy, 125 Chemin de Ronde, Croissy sur Seine, Paris 78290, France
    Neuropharmacology 44:604-15. 2003
    ..These data underpin interest in MDL100,907 as a potential antipsychotic agent...
  87. pmc Discriminative stimulus properties of indorenate, a serotonin agonist
    D N Velazquez-Martinez
    Depto Psicofisiología, Facultad de Psicologia, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    J Psychiatry Neurosci 24:122-30. 1999
    ..3H]-8-hydroxy-2-(di-N-propylamino) tetralin (8-OH-DPAT)...
  88. ncbi Modeling the forest transition: forest scarcity and ecosystem service hypotheses
    Akiko Satake
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Ecol Appl 17:2024-36. 2007
    ..These findings imply that incentives for forest conservation seem stronger in settings where forests regenerate slowly as well as when decision makers value the future...
  89. ncbi Generalization hypothesis of abstract-concept learning: learning strategies and related issues in Macaca mulatta, Cebus apella, and Columba livia
    Anthony A Wright
    Department of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Medical School, Houston, TX 77030, USA
    J Comp Psychol 121:387-97. 2007
    ..Thus, generalization was not a factor in the transfer from these experiments, adding to the evidence that these subjects were learning the S/D abstract concept...
  90. ncbi Pollinator diversity affects plant reproduction and recruitment: the tradeoffs of generalization
    José M Gómez
    Departmento de Ecologia, Universidad de Granada, Granada, Spain
    Oecologia 153:597-605. 2007
    ..This outcome suggests the existence of an optimal level of generalizations even for generalized plant species...
  91. ncbi Perfusion SPECT changes after acute and chronic vagus nerve stimulation in relation to prestimulus condition and long-term clinical efficacy
    Koenraad Van Laere
    Division of Nuclear Medicine, Ghent University Hospital, Ghent, Belgium
    J Nucl Med 43:733-44. 2002
    ..In this study, acute and chronic effects of VNS in patients with refractory complex partial seizures with or without secondary generalization (CPS +/- SG) were evaluated with respect to the prestimulus condition and long-term follow-up...
  92. ncbi [Male circumcision: hope for HIV infection decrease in southern Africa]
    Camille Legeai
    Unite d Epidemiologie, Hopital Ambroise Pare, 9, avenue du General de Gaulle, 92100 Boulogne Billancourt, France
    Med Sci (Paris) 24:499-504. 2008
    ..At the same time, research goes on in order to know more about the effects and to facilitate the generalization of this prevention mean which is a great hope for southern Africa...
  93. ncbi Characterization of the effects of receptor-selective ligands in rats discriminating the novel antipsychotic quetiapine
    Andrew J Goudie
    Psychology Department, Eleanor Rathbone Building, Liverpool University, Bedford Street, L69 7ZA, Liverpool, UK
    Psychopharmacology (Berl) 171:212-22. 2004
    ..Drug discrimination studies with clozapine have shown that such assays are of value in analysing the actions of novel antipsychotic agents in vivo...
  94. ncbi Response to traumatic brain injury neurorehabilitation through an artificial intelligence and statistics hybrid knowledge discovery from databases methodology
    Karina Gibert
    Department of Statistics and Operation Research, Universitat Politecnica de Catalunya, Barcelona, Spain
    Med Arh 62:132-5. 2008
    ..Develop a classificatory tool to identify different populations of patients with Traumatic Brain Injury based on the characteristics of deficit and response to treatment...
  95. ncbi [Economic implications of the various treatment methods in myocardial ischemia]
    J Y Artigou
    Service de cardiologie, , Paris
    Arch Mal Coeur Vaiss 80:101-4. 1987
    ..To what extent this increase will be upset by the benefits of avoided or limited infarction can only be determined by detailed and accurate evaluation...
  96. ncbi [Adding lamotrigine to the treatment of epilepsy which is difficult to control]
    P Suarez
    Servicio de Neurologia, Hospital General de Galicia, Clinico Universitario, Santiago de Compostela
    Rev Neurol 23:1190-2. 1995
    ..Two patients gave up other drugs and continued monotherapy using Lamotrigine. In nine of the ten Lennox-Gastaut syndrome patients the frequency of attacks went down by more than 50% and in seven such cases by more than 75%...
  97. ncbi Protein's native state stability in a chemically induced denaturation mechanism
    L Olivares-Quiroz
    Departamento de Fisica, Universidad Autonoma Metropolitana Iztapalapa, Mexico DF 09340, Mexico
    J Theor Biol 246:214-24. 2007 al., 2006. Protein Pept. Lett. 13(4), 323-329; Salem, M., et al., 2006. Biochim. Biophys. Acta 1764(5), 903-912] so EZM can shed some light into the physical meaning of the experimental values for the a,b,c coefficients...
  98. ncbi Antagonism of the discriminative stimulus effects of (+)-7-OH-DPAT by remoxipride but not PNU-99194A
    A J Christian
    Department of Psychology, Western Michigan University, Kalamazoo, MI 49008, USA
    Pharmacol Biochem Behav 68:371-7. 2001
    ..These findings suggest that D(2) receptors are critically involved in mediating the cue properties of (+)-7-OH-DPAT. However, alternative interpretations that PNU-99194A is not entirely D(3) receptor selective should also be considered...
  99. ncbi [Intellectual achievements of the epileptic child in primary school]
    E M Pestana
    , , Ciudad de La Habana, Cuba
    Rev Neurol 24:1513-5. 1996
  100. ncbi [Monotherapy with gabapentin ++]
    L Padro
    Servicio de Neurologia, Hospital General Universitari Vall d Hebron, Barcelona, Espana
    Rev Neurol 29:579-84. 1999
    ..Recently it has been approved for use as monotherapy. We review the characteristics of this molecule as an anti-epileptic drug and the clinical trials which have permitted approval of the current indications...
  101. ncbi Instantiated features and the use of "rules."
    Lee R Brooks
    Department of Psychology, McMaster University, Hamilton, ON, Canada
    J Exp Psychol Gen 135:133-51. 2006
    ..These 2 feature levels are crucial to provide broad generalization while reflecting the known peculiarities of a complex world...

Research Grants78

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
    MICHAEL NMN DAVIS; Fiscal Year: 2010
    ..The work is relevant to human anxiety disorders and promises to elucidate critical events in the formation and elimination of fear and anxiety. ..
  3. Mechanisms of Alcohol Withdrawal
    Dwayne W Godwin; Fiscal Year: 2012
  4. Neuronal Mechanisms for Fear Memory Generalization in PTSD and Anxiety Disorders
    Wei Xu; Fiscal Year: 2013
    ..Stanford University has been the cradle of fundamental neuroscience findings and innovative neuroscience approaches and will furnish the best environment for the studies. ..
  5. Brain Matters 3: Values at the Crossroads of Neurology, Psychiatry, and Psycholog
    PAUL JASON FORD; Fiscal Year: 2012
    ..In particular there is a focus on Psychogenic Non-epileptic Seizures, but a generalization to broader conditions such as post-traumatic stress disorder, pain syndromes, and psychogenic movement disorders. ..
  6. Transnasal Delivery of Chemokine Analogs in mouse NeuroAIDS Models
    Stuart A Lipton; Fiscal Year: 2013
    ..This model, as developed by our collaborator Dr. Howard Gendelman and colleagues, while more difficult to utilize, closely mimics human HAND progression and cognitive dysfunction. ..
  7. A Randomized trial of early palliative care for newly diagnosed cancer patients
    JENNIFER SUE TEMEL; Fiscal Year: 2013
    ..We hope that combining palliative care with traditional cancer treatment will not only prove beneficial for patients and their families but also transform comprehensive cancer care. ..
  8. Comprehensive SNP Discovery in SLC2A9. A Candidate Gene for Uric Acid Nephropathy
    Venkata Saroja Voruganti; Fiscal Year: 2013
  9. Sleep and the Generalization Extinction of Conditioned Fear
    Edward F Pace-Schott; Fiscal Year: 2012
    ..Additionally, results may suggest behavioral interventions and pharmacological strategies that can be applied to post-therapy sleep in order to preserve or enhance those aspects of sleep most beneficial for extinction generalization. ..
  10. Combined Cognitive and Gait Training
    Janis J Daly; Fiscal Year: 2012
    ..The proposed study has the potential to provide recovery of safe, coordinated gait in the everyday environment for many veterans who have had a stroke. ..
  11. Healthy Living Partnership to Prevent Diabetes (HELP PD) Phase 3 (formerly TRIP)
    Mara Z Vitolins; Fiscal Year: 2013
    ..Although preliminary data indicate that HELP PD has been successful at inducing short-term weight loss, the proposed project aims to examine the impact of long-term maintenance of weight loss on diabetes prevention. ..
    Daniel Herschlag; Fiscal Year: 2013
    ..Finally, we will take on the grand challenge of understanding how a functional RNA is assembled, in particular probing the roles and mode of action of remote elements that facilitate function within the catalytic core. ..
  13. Structural Studies of Enzymes of Thiamin Biosynthesis
    Steven E Ealick; Fiscal Year: 2013
    ..The research has implications for the commercial production of thiamin using fermentation, and for the development of antimicrobial agents that target thiamin biosynthesis. ..
    Alan C Spector; Fiscal Year: 2010
    ..These experiments will psychophysically define the contribution of an important class of taste receptors to normal gustatory function in the mouse model, which is becoming widely adopted for study of mammalian chemosensory processes. ..
  15. Opioid Antagonist Discrimination: A Model of Withdrawal
    Alison Oliveto; Fiscal Year: 2011
    ..This paradigm provides a sensitive, standard, objective, systematic method to identify potential agents for enhancing OW treatment which can be examined further in a detox protocol. ..
  16. Environment-person Influences on the Development of Early Alcohol Use and Misuse
    Richard F Catalano; Fiscal Year: 2010
    ..Analyses will help identify modifiable influences such as school policy and family practices that can be used to prevent these problems of primary importance to the public health community. ..
  17. Smoked Marijuana Discrimination and Marijuana Choice in Humans: A Laboratory Mode
    Leslie H Lundahl; Fiscal Year: 2010
    ..e., behavioral treatments), which together might have the greatest potential to lead to integrative and successful treatment for cannabis related disorders. ..
  18. Temporal Coding in the Gustatory System of the Brain
    Patricia M Di Lorenzo; Fiscal Year: 2013
    ..These principles can then be applied to the design and implementation of brain-machine interfaces, such as sensory prostheses that are used to improve the lives of people with severe injuries to their limbs or spinal cord. ..
  19. Elucidating CIS-Acting Elements Regulating Alcohol-Induced Alternative Splicing
    YUNLONG contact LIU; Fiscal Year: 2010
  20. Treatment as usual and peer engagement in teens with High Functioning Autism
    Felice Orlich; Fiscal Year: 2010
  21. HIV Transmission Cluster Analysis to Inform Prevention
    Hong Ha M Truong; Fiscal Year: 2013
    ..Real-time analysis of HIV transmission cluster data will place us on the leading edge of the epidemic and enable assessment of how high-risk clusters and current prevention strategies affect transmission patterns. ..
  22. Molecular Controls over Callosal Projection Neuron Subtype Specification and Dive
    RYAN MARIE FAME; Fiscal Year: 2012
  23. Functional Organization of the Bed Nucleus of the Stria Terminalis
    DENIS PARE; Fiscal Year: 2013
    ..Given that similar networks underlie fear learning in animals and humans, the proposed studies might shed light on the pathophysiology of anxiety disorders. ..
  24. A Prospective Model of Medicare Cost Trajectories
    Douglas A Wolf; Fiscal Year: 2011
  25. Microstructural Characterization of White Matter in Schizophrenia
    Mariana Lazar; Fiscal Year: 2010
  26. The role of variability in infants'phonological learning
    CAROLYN MARIE QUAM; Fiscal Year: 2013
    ..In particular, variability on an irrelevant but salient dimension could potentially be used to draw children's attention to the relevant dimension, improving learning. ..
  27. Post-Traumatic Stress Disorder and Alcohol Dependence
    Nicholas W Gilpin; Fiscal Year: 2013
    ..e. corticotropin- releasing factor [CRF], neuropeptide Y [NPY], and norepinephrine [NE]) and ubiquitous in these limbic circuits are similarly and additively dysregulated in PTSD and alcohol dependence. ..
  28. Use of External Cueing to Treat Hypophonia in Parkinson's Disease
    Jessica E Huber; Fiscal Year: 2012
    ..The intervention proposed is unique because it provides a naturalistic external cue and trains the individuals during activities of daily living. ..
  29. Teacher-Child Interaction Training: A Classroom-Based Preschool Intervention
    Christopher Campbell; Fiscal Year: 2013
  30. The Virtual Patient for Improving Quality of Care in Primary Healthcare
    Richard Mollica; Fiscal Year: 2012
    ..The VP as a HIT innovation can provide sustainable training and quality of care improvement for disadvantaged patients and their PHC providers. ..
  31. An Exploratory Model of Early Speech Intervention for Children with Cleft Palate
    Nancy J Scherer; Fiscal Year: 2010
    ..This model will be compared to a traditional articulation treatment provided in the community. ..
  32. Feelings/Body Investigators:Interoceptive Exposure for Children w/Abdominal Pain
    Nancy L Zucker; Fiscal Year: 2013
    ..The success of our early intervention for FAP in young children will also have broad implications for the treatment and prevention of mental illness and chronic abdominal pain. ..
  33. Basic and Comparative Studies of CCR5 Inhibition to Prevent HIV Transmission
    MICHAEL MARCEL LEDERMAN; Fiscal Year: 2010
    ..This approach will generate better and safer CCR5 inhibitors that can be produced on a scale suitable for stopping the spread of HIV/AIDS in the most-impacted areas. ..
    Timothy J Wolf; Fiscal Year: 2013
  35. Revisiting Challenged Findings to Determine Social and Cognitive Abilities
    Julie J Neiworth; Fiscal Year: 2012
    ..The project also completes the scientific process by re-examining important questions related to primate cognition and the evolution of the human mind that have fallen under scrutiny. ..
  36. Neural Correlates of Discrimination and Generalization in Recognition Memory
    PETER EDWARD WAIS; Fiscal Year: 2013
    ..Finally, additional experiments with younger adults will use repetitive TMS to test the causal role of cortical regions of interest in the functional memory networks. ..
  37. Training of Gist-Based Strategic Reasoning in Adolescents with Chronic Traumatic
    Sandra Bond Chapman; Fiscal Year: 2010
  38. Extinction of Limbic Activation to "Unseen" Cocaine Cues
    Anna Rose Childress; Fiscal Year: 2010
    ..The current project tests whether extinction of the brain response to cocaine cues can occur outside awareness, and whether extinction can be facilitated by the partial agonist varenicline. ..
  39. Sleep and Child Developmental Outcomes: Physiological and Contextual Influences
    MONA M EL-SHEIKH; Fiscal Year: 2012
  40. Clot Lysis: Evaluating Accelerated Resolution of IVH Phase III (CLEAR III)
    Daniel F Hanley; Fiscal Year: 2013
  41. Emotion Regulation in Anxiety &Depression: A Novel Neurobehavioral Intervention
    Amit Etkin; Fiscal Year: 2013
  42. Mechanisms of cellular osmosensing and osmotic stress induced damage repair
    Kevin Strange; Fiscal Year: 2013
  43. Effects of Speech in Noise Training on Physiology and Perception
    Curtis J Billings; Fiscal Year: 2012
    ..Behavioral and physiological measures will be used to measure the effects of speech-in-noise training with the long-term goal of improving perception in noise in older individuals and individuals with hearing loss. ..
  44. Brain mechanisms supporting the generalization of learned fear
    JOSEPH EDWARD DUNSMOOR; Fiscal Year: 2012
    ..g. specific phobias and posttraumatic stress disorder) and may lead to model systems important for the treatment and prevention of these disorders. ..
  45. Skills Training and Empowerment Program for Middle-Aged and Older Patients with P
    Brent T Mausbach; Fiscal Year: 2013
    ..Group differences in functional outcomes will be determined based upon assessments made at baseline, 6-, 12-, and 18-months post-baseline. ..
  46. Neural and Behavioral Outcomes of Social Skills Groups in Children with ASD
    A TING contact WANG; Fiscal Year: 2010
    ..Toward this effort, the proposed study is a randomized controlled investigation designed to evaluate short-term effects and maintenance of skills taught in CBT-based social skills groups, at both the behavioral and neural levels. ..
  47. Generalization of Conditioned Fear as a Pathogenic Marker of PTSD
    SHMUEL MORDECHAI LISSEK; Fiscal Year: 2012
    ..One central hypothesis of the current application is that those with PTSD will display less steep gradients of generalization (i.e., more fear generalization) compared to healthy controls. ..
  48. Locomotor Adaptations Following Stroke
    Darcy S Reisman; Fiscal Year: 2010
    ..This research investigates the potential of a novel type of treadmill walking to influence coordination between the legs in persons who have sustained a stroke. ..
  49. Augmenting Social Cognitive Intervention for Veterans with Schizophrenia
    Michael F Green; Fiscal Year: 2013
    ..The long-term goal of this project is to develop effective treatments for social cognitive deficits to help individuals with schizophrenia function better in their daily lives. ..
  50. Neural and computational mechanisms of selective attention in decision making
    Yael Niv; Fiscal Year: 2013
    ..In the long term, the proposed research will potentially impact on the study and treatment of these disorders. ..
  51. Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving, Reactivity &Use
    Michael E Saladin; Fiscal Year: 2013
    ..Confirmation of these expectations will set the stage for a clinical trial where the outcome enhancing properties of this novel pharmacy-behavior therapy could be systematically evaluated. ..
  52. Neurocognitive Effects of Stress
    Jeansok John Kim; Fiscal Year: 2012
    ..abstract_text> ..
  53. Implementation of evidence-based treatments for on-campus eating disorders
    G T Wilson; Fiscal Year: 2013
    ..Proctor and Raghavan who are co-investigators on this project. ..
  54. Time Perception and Timed Performance in Autism
    Melissa J Allman; Fiscal Year: 2010
    ..This in turn may lead to advances in early detection and behavioral interventions, and inform related lines of research (e.g., joint attention). ..
  55. Analysis of properties of HIV-1 subtype C envelope glycoprotein
    Nina H Lin; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE (provided by applicant): Understanding mechanisms of HIV pathogenesis, transmission and clinical progression will have public health relevance by guiding the design of HIV prevention and treatment strategies. ..
  56. The Neural Substrates of Higher-Level Learning in Autism
    Marjorie Solomon; Fiscal Year: 2013
  57. Trial of Transition to Parenting Program for Couples
    MARK ETHAN FEINBERG; Fiscal Year: 2012
    ..The transition to parenthood is a stressful period for many couples. Developing and disseminating new, effective preventive programs such as the one proposed would have substantial public health benefits for couples and their children. ..
  58. Aphasia Rehabilitation: Modulating Cues, Feedback &Practice
    Sarel van Vuuren; Fiscal Year: 2013
  59. Markov Models of Potassium Channel Gating
    Randall L Rasmusson; Fiscal Year: 2012
    ..The long term goal is to predict clinical phenotype directly from channel defect. ..
  60. Discrimination of What, Where, and When
    Jonathon D Crystal; Fiscal Year: 2011
    ..Therefore, investigating the discrimination of what, where, and when in animals holds enormous potential for understanding the neurobiological bases of human memory disorders. ..
    Charles A Greer; Fiscal Year: 2013
    ..abstract_text> ..
  62. Social Consequences of Mental Disorders: A Ten-Year Follow-up Study
    Ramin Mojtabai; Fiscal Year: 2013
    ..Results of the study could be useful in ongoing policy debates about the importance of investing in research and treatment of mental disorders and could help identify subgroups for targeted intervention to avert adverse social outcomes. ..
    Chester Whitley; Fiscal Year: 1993
    ..These studies will further delineate the potentially broad application of BMT for inborn errors of metabolism, and will be crucial in defining the requisites for future attempts at gene therapy...
    RICHARD GLENNON; Fiscal Year: 1999
    ..Because preliminary data suggest that certain of these agents bind at serotonin and tryptamine receptors, the project will initially focus on these two neurotransmitter mechanisms. ..
  65. Theoretically based treatment for sentence comprehension deficits in aphasia
    Swathi Kiran; Fiscal Year: 2009
    ..The result is expected to be an effective and efficient training protocol that can be used to treat deficits in syntactically based comprehension people with aphasia. ..
    SAMUEL GAERTNER; Fiscal Year: 2001
  67. Fundamentals of Interpersonal Therapy
    Scott Stuart; Fiscal Year: 2009
    ..The direct public health benefit of the project is that increasing dissemination of evidence-based practices like IPT will increase accessibility of efficacious treatment and lead to better outcomes for patients with depression. ..
  68. Extending Social Skills Training for Children Through Interactive Technology
    MELISSA DEROSIER; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
    William Fisher; Fiscal Year: 1999
    ..The proposal concludes with suggestions for a multi-center pilot of interlaboratory trials and reference standard implementations in live clinical settings. ..
  70. Generalization of the Client Matching Protocol
    George De Leon; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  71. Community Skills Video Game for Children with Autism
    AMY MAGUIRE; Fiscal Year: 2005
    ..Social relevance to parents and professionals will be examined with a survey. This Phase I feasibility study will provide the foundation for Phase II evaluation of outcomes across a greater number of skills and participants. ..
    Christian Grillon; Fiscal Year: 1999
    ..The results will also provide the necessary foundation for further pharmacological and clinical studies of conditioned fear and conditioned fear inhibition in humans. ..
  73. Portable Guidance in Autism Spectrum Disorder
    Gary Mesibov; Fiscal Year: 2005
    ..Health Relatedness: The PSVG/SymTrend system will provide an opportunity for countless people with AS/HFA and other disabilities to function more productively/independently and lead more gratifying lives. ..
  74. Robust Generalization in MHC Peptide Binding Models
    Pedro Cano; Fiscal Year: 2002
  75. Behavior Therapy for Children with Chronic Tic Disorders
    John Piacentini; Fiscal Year: 2007
    ..The Yale Infomatics group will provide data management services. ..
    Patricia Resick; Fiscal Year: 2004
    ..At a theoretical level, the proposed study will also provide an opportunity to investigate theoretical mechanisms hypothesized to be involved in recovery from PTSD. ..
    JOHN FORSYTH; Fiscal Year: 2001
    ..abstract_text> ..
    THEREASA CRONAN; Fiscal Year: 2000
    ..If either of the interventions reduce health care costs by $1200 per person per year, as expected, the long- term savings will be great. ..