cues

Summary

Summary: Signals for an action; that specific portion of a perceptual field or pattern of stimuli to which a subject has learned to respond.

Top Publications

  1. ncbi Rhythmic growth explained by coincidence between internal and external cues
    Kazunari Nozue
    Section of Plant Biology, College of Biological Sciences, University of California, Davis, One Shields Avenue, Davis, California 95616, USA
    Nature 448:358-61. 2007
  2. ncbi Odor cues during slow-wave sleep prompt declarative memory consolidation
    Björn Rasch
    Department of Neuroendocrinology, University of Lubeck, Ratzeburger Allee 160 23a, 23538 Lubeck, Germany
    Science 315:1426-9. 2007
  3. ncbi Ocean acidification disrupts the innate ability of fish to detect predator olfactory cues
    Danielle L Dixson
    ARC Centre of Excellence for Coral Reef Studies, and School of Marine and Tropical Biology, James Cook University, Townsville, Qld 4811, Australia
    Ecol Lett 13:68-75. 2010
  4. ncbi Unconscious attentional orienting to exogenous cues: A review of the literature
    Manon Mulckhuyse
    Vrije Universiteit, Amsterdam, The Netherlands
    Acta Psychol (Amst) 134:299-309. 2010
  5. pmc Adult attachment predicts maternal brain and oxytocin response to infant cues
    Lane Strathearn
    Department of Pediatrics, The Meyer Center for Developmental Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, TX 77030, USA
    Neuropsychopharmacology 34:2655-66. 2009
  6. ncbi A neural substrate of prediction and reward
    W Schultz
    Institute of Physiology, University of Fribourg, CH 1700 Fribourg, Switzerland
    Science 275:1593-9. 1997
  7. pmc Gaze cueing of attention: visual attention, social cognition, and individual differences
    Alexandra Frischen
    Macquarie Centre for Cognitive Science, Macquarie University, Sydney, NSW, Australia
    Psychol Bull 133:694-724. 2007
  8. ncbi Merging the senses into a robust percept
    Marc O Ernst
    Max Planck Institut für biologische Kybernetik, Tubingen, Germany
    Trends Cogn Sci 8:162-9. 2004
  9. ncbi Temporal prediction errors in a passive learning task activate human striatum
    Samuel M McClure
    Human Neuroimaging Lab, Center for Theoretical Neuroscience, Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Neuron 38:339-46. 2003
  10. ncbi The first taste is always with the eyes: a meta-analysis on the neural correlates of processing visual food cues
    L N van der Laan
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Neuroimage 55:296-303. 2011

Detail Information

Publications334 found, 100 shown here

  1. ncbi Rhythmic growth explained by coincidence between internal and external cues
    Kazunari Nozue
    Section of Plant Biology, College of Biological Sciences, University of California, Davis, One Shields Avenue, Davis, California 95616, USA
    Nature 448:358-61. 2007
    ..This interaction may serve as a paradigm for understanding how endogenous and environmental signals cooperate to control other processes...
  2. ncbi Odor cues during slow-wave sleep prompt declarative memory consolidation
    Björn Rasch
    Department of Neuroendocrinology, University of Lubeck, Ratzeburger Allee 160 23a, 23538 Lubeck, Germany
    Science 315:1426-9. 2007
    ..Concurring with these findings, functional magnetic resonance imaging revealed significant hippocampal activation in response to odor re-exposure during SWS...
  3. ncbi Ocean acidification disrupts the innate ability of fish to detect predator olfactory cues
    Danielle L Dixson
    ARC Centre of Excellence for Coral Reef Studies, and School of Marine and Tropical Biology, James Cook University, Townsville, Qld 4811, Australia
    Ecol Lett 13:68-75. 2010
    ..we show that newly hatched larvae of the marine fish Amphiprion percula innately detect predators using olfactory cues and this ability is retained through to settlement...
  4. ncbi Unconscious attentional orienting to exogenous cues: A review of the literature
    Manon Mulckhuyse
    Vrije Universiteit, Amsterdam, The Netherlands
    Acta Psychol (Amst) 134:299-309. 2010
    ..We discuss studies that use peripheral masked onset cues and studies that use gaze cueing...
  5. pmc Adult attachment predicts maternal brain and oxytocin response to infant cues
    Lane Strathearn
    Department of Pediatrics, The Meyer Center for Developmental Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, TX 77030, USA
    Neuropsychopharmacology 34:2655-66. 2009
    Infant cues, such as smiling or crying facial expressions, are powerful motivators of human maternal behavior, activating dopamine-associated brain reward circuits...
  6. ncbi A neural substrate of prediction and reward
    W Schultz
    Institute of Physiology, University of Fribourg, CH 1700 Fribourg, Switzerland
    Science 275:1593-9. 1997
    ..Taken together, these findings can be understood through quantitative theories of adaptive optimizing control...
  7. pmc Gaze cueing of attention: visual attention, social cognition, and individual differences
    Alexandra Frischen
    Macquarie Centre for Cognitive Science, Macquarie University, Sydney, NSW, Australia
    Psychol Bull 133:694-724. 2007
    ..The contribution of this paradigm has been significant and will likely continue to advance knowledge across diverse fields within psychology and neuroscience...
  8. ncbi Merging the senses into a robust percept
    Marc O Ernst
    Max Planck Institut für biologische Kybernetik, Tubingen, Germany
    Trends Cogn Sci 8:162-9. 2004
    ..We show that, depending on the type of information, different combination and integration strategies are used and that prior knowledge is often required for interpreting the sensory signals...
  9. ncbi Temporal prediction errors in a passive learning task activate human striatum
    Samuel M McClure
    Human Neuroimaging Lab, Center for Theoretical Neuroscience, Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Neuron 38:339-46. 2003
    ....
  10. ncbi The first taste is always with the eyes: a meta-analysis on the neural correlates of processing visual food cues
    L N van der Laan
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Neuroimage 55:296-303. 2011
    ..Therefore, future research should further elucidate the separate effects of methodological and physiological factors on between-study variations...
  11. ncbi The use of multiple cues in mate choice
    Ulrika Candolin
    Department of Ecology and Systematics, P O Box 65, University of Helsinki, Helsinki FIN 00014, Finland
    Biol Rev Camb Philos Soc 78:575-95. 2003
    An increasing number of studies find females to base their mate choice on several cues. Why this occurs is debated and many different hypotheses have been proposed. Here I review the hypotheses and the evidence in favour of them...
  12. ncbi The architecture of cognitive control in the human prefrontal cortex
    Etienne Koechlin
    Institut National de la Sante et de Recherche Medicale, Universite Pierre et Marie Curie, 9, quai St Bernard, 75005 Paris, France
    Science 302:1181-5. 2003
    ..The results support an unified modular model of cognitive control that describes the overall functional organization of the human lateral PFC and has basic methodological and theoretical implications...
  13. pmc Neuron-type-specific signals for reward and punishment in the ventral tegmental area
    Jeremiah Y Cohen
    Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 482:85-8. 2012
    ..We recorded the activity of VTA neurons while mice associated different odour cues with appetitive and aversive outcomes...
  14. ncbi Cues to deception
    Bella M DePaulo
    Department of Psychology, University of Virginia, USA
    Psychol Bull 129:74-118. 2003
    ..when they are lying compared with when they are telling the truth? The combined results of 1,338 estimates of 158 cues to deception are reported...
  15. pmc Emotion facilitates perception and potentiates the perceptual benefits of attention
    Elizabeth A Phelps
    Department of Psychology and Center for Neural Science, New York University, NY 10003, USA
    Psychol Sci 17:292-9. 2006
    ..We manipulated the emotional valence and the attentional distribution of cues preceding a target stimulus and asked observers to judge the orientation of the target as contrast varied...
  16. pmc Remembering the past and imagining the future: common and distinct neural substrates during event construction and elaboration
    Donna Rose Addis
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Neuropsychologia 45:1363-77. 2007
    ..This striking neural overlap is consistent with findings that amnesic patients exhibit deficits in both past and future thinking, and confirms that the episodic system contributes importantly to imagining the future...
  17. ncbi Valid facial cues to cooperation and trust: male facial width and trustworthiness
    M Stirrat
    University of St Andrews, School of Psychology, St Mary s Quad, St Andrews, Fife KY16 0HE, United Kingdom
    Psychol Sci 21:349-54. 2010
    ..Moreover, manipulating this facial-width ratio with computer graphics controlled attributions of trustworthiness, particularly for subordinate female evaluators...
  18. ncbi Independent codes for spatial and episodic memory in hippocampal neuronal ensembles
    Stefan Leutgeb
    Centre for the Biology of Memory, Medical Technical Research Centre, Norwegian University of Science and Technology, 7489 Trondheim, Norway
    Science 309:619-23. 2005
    ..These independent encoding schemes may enable simultaneous representation of spatial and episodic memory information...
  19. ncbi Neural responses during anticipation of a primary taste reward
    JOHN P O'DOHERTY
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, WC1 3BG, London, United Kingdom
    Neuron 33:815-26. 2002
    ..Using fMRI, we scanned human subjects who were presented with visual cues that signaled subsequent reinforcement with a pleasant sweet taste (1 M glucose), a moderately unpleasant salt ..
  20. pmc Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele
    E Stice
    Oregon Research Institute, 1715 Franklin Boulevard, Eugene, OR 97403, USA
    Science 322:449-52. 2008
    ....
  21. pmc Quantifying individual variation in the propensity to attribute incentive salience to reward cues
    Paul J Meyer
    Department of Psychology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 7:e38987. 2012
    If reward-associated cues acquire the properties of incentive stimuli they can come to powerfully control behavior, and potentially promote maladaptive behavior...
  22. ncbi Food and drug cues activate similar brain regions: a meta-analysis of functional MRI studies
    D W Tang
    Department of Psychology, McGill University, Montreal Neurological Institute, Montreal, QC, Canada
    Physiol Behav 106:317-24. 2012
    In healthy individuals, food cues can trigger hunger and feeding behavior. Likewise, smoking cues can trigger craving and relapse in smokers...
  23. ncbi The construction of autobiographical memories in the self-memory system
    M A Conway
    Department of Experimental Psychology, University of Bristol, England
    Psychol Rev 107:261-88. 2000
    ..Within the SMS, control processes modulate access to the knowledge base by successively shaping cues used to activate autobiographical memory knowledge structures and, in this way, form specific memories...
  24. ncbi Compatibility between observed and executed finger movements: comparing symbolic, spatial, and imitative cues
    M Brass
    Department of Neurology, Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany
    Brain Cogn 44:124-43. 2000
    ..In the first experiment, we compared symbolic cues with observed finger movements using an interference paradigm...
  25. ncbi A mechanism for impaired fear recognition after amygdala damage
    Ralph Adolphs
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Nature 433:68-72. 2005
    ..This finding provides a mechanism to explain the amygdala's role in fear recognition, and points to new approaches for the possible rehabilitation of patients with defective emotion perception...
  26. ncbi Widespread reward-system activation in obese women in response to pictures of high-calorie foods
    Luke E Stoeckel
    Department of Psychology, University of Alabama at Birmingham, Birmingham, AL 35294 1170, USA
    Neuroimage 41:636-47. 2008
    Behavioral studies have suggested that exaggerated reactivity to food cues, especially those associated with high-calorie foods, may be a factor underlying obesity...
  27. ncbi Perception of scene-relative object movement: Optic flow parsing and the contribution of monocular depth cues
    Paul A Warren
    School of Psychology and Communications Research Centre, Cardiff University, Cardiff, CF10 3AT Wales, UK
    Vision Res 49:1406-19. 2009
    ..Across conditions we varied the presence or absence of different binocular and monocular cues to depth order...
  28. pmc An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 35:388-400. 2010
    ..of animals, which differ in their propensity to self-administer drugs, also differ in the value they attribute to cues associated with reward, in impulsive behavior, and in their dopamine system...
  29. pmc Activation of VTA GABA neurons disrupts reward consumption
    Ruud van Zessen
    Departments of Psychiatry and Cellular and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Neuron 73:1184-94. 2012
    ..disrupts reward consummatory behavior but not conditioned anticipatory behavior in response to reward-predictive cues. In addition, direct activation of VTA GABA projections to the nucleus accumbens (NAc) resulted in detectable GABA ..
  30. ncbi Public information: from nosy neighbors to cultural evolution
    Etienne Danchin
    U P M C CNRS UMR7625, Bât A 7e étage Case 237, 7 quai Saint Bernard, 75252 Paris Cedex 05, France
    Science 305:487-91. 2004
    ..Individuals can use information arising from cues inadvertently produced by the behavior of other individuals with similar requirements...
  31. pmc Autobiographical memory specificity and emotional disorder
    J Mark G Williams
    Department of Psychiatry, University of Oxford, Oxford, UK
    Psychol Bull 133:122-48. 2007
    ....
  32. pmc Individual differences in nucleus accumbens activity to food and sexual images predict weight gain and sexual behavior
    Kathryn E Demos
    Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
    J Neurosci 32:5549-52. 2012
    ..One reason that people may be prone to engaging in unwanted behaviors is heightened sensitivity to cues related to those behaviors; people may overeat because of hyperresponsiveness to food cues, addicts may relapse ..
  33. pmc The effects of exercise on the neuronal response to food cues
    Marc Andre Cornier
    Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA
    Physiol Behav 105:1028-34. 2012
    ..of this study was to examine the effects of exercise training and acute exercise on the neuronal response to food cues as well as eating behaviors...
  34. ncbi Cortical dynamics of contextually cued attentive visual learning and search: spatial and object evidence accumulation
    Tsung Ren Huang
    Department of Cognitive and Neural Systems, Center for Adaptive Systems, Boston University, 677 Beacon Street, Boston, MA 02215, USA
    Psychol Rev 117:1080-112. 2010
    ..Model ventral prefrontal cortex (area 47/12) primes possible target identities in inferior temporal cortex based on the history of viewed objects represented in perirhinal cortex...
  35. ncbi Atypical brain responses to reward cues in autism as revealed by event-related potentials
    Gregor Kohls
    Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    J Autism Dev Disord 41:1523-33. 2011
    ..In this study, we investigated event-related brain potentials evoked by cues that triggered social versus monetary reward anticipation in children with autism...
  36. ncbi Empathy for pain involves the affective but not sensory components of pain
    Tania Singer
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College of London, 12 Queen Square, WC1N 3AR London, UK
    Science 303:1157-62. 2004
    ..We conclude that only that part of the pain network associated with its affective qualities, but not its sensory qualities, mediates empathy...
  37. ncbi Involvement of the dorsal striatum in cue-controlled cocaine seeking
    Louk J M J Vanderschuren
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 25:8665-70. 2005
    ..In addition, given the importance of the dorsal striatum in stimulus-response habit learning, these data suggest that the habitual or compulsive quality of persistent drug seeking depends on dorsal striatal mechanisms...
  38. ncbi Neural systems underlying the suppression of unwanted memories
    Michael C Anderson
    Department of Psychology, University of Oregon, Eugene, OR 97403, USA
    Science 303:232-5. 2004
    ..These results confirm the existence of an active forgetting process and establish a neurobiological model for guiding inquiry into motivated forgetting...
  39. ncbi The facilitated processing of threatening faces: an ERP analysis
    Harald T Schupp
    Department of Psychology, University of of Greifswald, Greifswald, Germany
    Emotion 4:189-200. 2004
    ..Taken together, these data demonstrate the facilitated perceptual processing of threatening faces. Results are discussed within the context of an evolved module of fear (A. Ohman & S. Mineka, 2001)...
  40. ncbi The domestication of social cognition in dogs
    Brian Hare
    Department of Anthropology, Harvard University, Cambridge, MA 02138, USA
    Science 298:1634-6. 2002
    ..These findings suggest that during the process of domestication, dogs have been selected for a set of social-cognitive abilities that enable them to communicate with humans in unique ways...
  41. ncbi Action sets and decisions in the medial frontal cortex
    M F S Rushworth
    Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
    Trends Cogn Sci 8:410-7. 2004
    ....
  42. ncbi Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice
    C Rampon
    Department of Molecular Biology, Princeton University, Washington Road, Princeton, New Jersey 08540 1014, USA
    Nat Neurosci 3:238-44. 2000
    ..Therefore, our data indicate that CA1 NMDA receptor activity is critical in hippocampus-dependent nonspatial memory, but is not essential for experience-induced synaptic structural changes...
  43. ncbi Effects of visual and auditory cues on gait initiation in people with Parkinson's disease
    Ying Jiang
    School of Rehabilitation Therapy, Queen s University, Kingston, Ontario, Canada
    Clin Rehabil 20:36-45. 2006
    To evaluate the effects of auditory and visual cues on gait initiation in people with Parkinson's disease.
  44. ncbi Context and behavioral processes in extinction
    Mark E Bouton
    Department of Psychology, University of Vermont, Burlington, Vermont 05405, USA
    Learn Mem 11:485-94. 2004
    ....
  45. ncbi Task set and prefrontal cortex
    Katsuyuki Sakai
    Department of Cognitive Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Annu Rev Neurosci 31:219-45. 2008
    ..The processes of representing, updating, and implementing task sets occur in parallel at multiple levels of brain organization. Neural accounts of task sets demonstrate that the brain determines our thoughts and behaviors...
  46. ncbi Functional neuroanatomy of aversion and its anticipation
    Jack B Nitschke
    The Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Department of Psychiatry, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705 2280, USA
    Neuroimage 29:106-16. 2006
    ..These results show that anticipation of aversion recruits key brain regions that respond to aversion, thereby potentially enhancing adaptive responses to aversive events...
  47. ncbi Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction
    Nora D Volkow
    National Institute on Alcohol Abuse and Alcoholism, Bethesda Maryland 20892, USA
    J Neurosci 26:6583-8. 2006
    ..Because craving is a key contributor to relapse, strategies aimed at inhibiting dopamine increases from conditioned responses are likely to be therapeutically beneficial in cocaine addiction...
  48. ncbi Orienting attention in time: behavioural and neuroanatomical distinction between exogenous and endogenous shifts
    J T Coull
    Wellcome Department of Cognitive Neurology, Institute of Neurology, 12 Queen Square, London, UK
    Neuropsychologia 38:808-19. 2000
    ..trials were shorter than those for invalid trials, demonstrating appropriate allocation of attention to temporal cues. All trial-types activated a shared system, including frontoparietal areas bilaterally, showing that this network ..
  49. ncbi Individual differences in reward drive predict neural responses to images of food
    John D Beaver
    Brain Sciences Unit, Medical Research Council Cognition, Cambridge CB2 2EF, United Kingdom
    J Neurosci 26:5160-6. 2006
    ..Our findings demonstrate that there is considerable personality-linked variability in the neural response to food cues in healthy participants and provide important insight into the neurobiological factors underlying vulnerability to ..
  50. pmc A new auditory multi-class brain-computer interface paradigm: spatial hearing as an informative cue
    Martijn Schreuder
    Machine Learning Department, Berlin Institute of Technology, Berlin, Germany
    PLoS ONE 5:e9813. 2010
    ..Therefore, a multi-class BCI paradigm is proposed that uses spatially distributed, auditory cues. Ten healthy subjects participated in an offline oddball task with the spatial location of the stimuli being a ..
  51. pmc Causal inference in multisensory perception
    Konrad P Kording
    Rehabilitation Institute of Chicago, Northwestern University, Chicago, Illinois, USA
    PLoS ONE 2:e943. 2007
    ..We formulate an ideal-observer model that infers whether two sensory cues originate from the same location and that also estimates their location(s)...
  52. pmc Individual differences in the attribution of incentive salience to reward-related cues: Implications for addiction
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropharmacology 56:139-48. 2009
    ..Thus in addicts, exposure to places or things (cues) that has been previously associated with drug-taking often instigates renewed drug-taking...
  53. ncbi Attentional bias in addictive behaviors: a review of its development, causes, and consequences
    Matt Field
    School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool, UK
    Drug Alcohol Depend 97:1-20. 2008
    ..We make several predictions that require testing in future research, and we discuss implications for the treatment of addictive behaviors...
  54. ncbi Phonotactic cues for segmentation of fluent speech by infants
    S L Mattys
    Department of Psychology, Johns Hopkins University, MD, Baltimore, USA
    Cognition 78:91-121. 2001
    ..The present study investigates whether 9-month-olds make use of phonotactic cues to segment words from fluent speech...
  55. pmc Localized netrins act as positional cues to control layer-specific targeting of photoreceptor axons in Drosophila
    Katarina Timofeev
    Division of Molecular Neurobiology, MRC National Institute for Medical Research, London, UK
    Neuron 75:80-93. 2012
    ..We propose that provision of localized chemoattractants by intermediate target neurons represents a highly precise strategy to direct axons to a positionally defined layer...
  56. pmc Psychopathic tendencies and mesolimbic recruitment by cues for instrumental and passively obtained rewards
    James M Bjork
    Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
    Biol Psychol 89:408-15. 2012
    ..These data indicate that in psychiatrically healthy controls, individuals with greater endorsement of psychopathic tendencies show more robust neurophysiological and behavioral signatures of incentive motivation...
  57. ncbi Classical fear conditioning in the anxiety disorders: a meta-analysis
    Shmuel Lissek
    Mood and Anxiety Disorders Program, National Institute of Mental Health, 15K North Drive, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
    Behav Res Ther 43:1391-424. 2005
    ..differences are not apparent when looking at discrimination studies alone and primarily emerge from studies employing simple, single-cue paradigms where only danger cues are presented and no inhibition of fear to safety cues is required.
  58. pmc Coral reef fish rapidly learn to identify multiple unknown predators upon recruitment to the reef
    Matthew D Mitchell
    Australia Research Council Centre of Excellence for Coral Reef Studies and School of Marine and Tropical Biology, James Cook University, Townsville, Australia
    PLoS ONE 6:e15764. 2011
    ..Upon entering an unfamiliar environment prey species are able to rapidly assess the risk of predation, enhancing their chances of survival, through the assessment of chemical stimuli...
  59. ncbi Modulating the sense of agency with external cues
    James W Moore
    Institute of Cognitive Neuroscience, University College London, London, UK
    Conscious Cogn 18:1056-64. 2009
    ..We propose that sense of agency is based on a combination of internal motoric signals and external sensory evidence about the source of actions and effects...
  60. pmc Detecting sarcasm from paralinguistic cues: anatomic and cognitive correlates in neurodegenerative disease
    Katherine P Rankin
    Memory and Aging Center, University of California San Francisco, Department of Neurology, San Francisco, CA 94143 1207, USA
    Neuroimage 47:2005-15. 2009
    While sarcasm can be conveyed solely through contextual cues such as counterfactual or echoic statements, face-to-face sarcastic speech may be characterized by specific paralinguistic features that alert the listener to interpret the ..
  61. pmc Interaction between dysfunctional connectivity at rest and heroin cues-induced brain responses in male abstinent heroin-dependent individuals
    Jixin Liu
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    PLoS ONE 6:e23098. 2011
    ..Yet few studies considered the relevance of resting state dysfunctional connectivity to task-related neural activity in the same chronic heroin user (CHU)...
  62. ncbi A representation of the hazard rate of elapsed time in macaque area LIP
    Peter Janssen
    Howard Hughes Medical Institute, National Primate Research Center and Department of Physiology and Biophysics, University of Washington, Box 357290, Seattle, Washington 98195, USA
    Nat Neurosci 8:234-41. 2005
    The capacity to anticipate the timing of environmental cues allows us to allocate sensory resources at the right time and prepare actions...
  63. pmc Sustained preferential processing of social threat cues: bias without competition?
    Matthias J Wieser
    University of Florida, USA
    J Cogn Neurosci 23:1973-86. 2011
    Stimuli of high emotional significance such as social threat cues are preferentially processed in the human brain...
  64. pmc The architecture of human kin detection
    Debra Lieberman
    Center for Evolutionary Psychology, University of California Santa Barbara, Santa Barbara, California 93106, USA
    Nature 445:727-31. 2007
    ..The cues that the system uses were identified by quantitatively matching individual exposure to potential cues of ..
  65. ncbi BOLD responses reflecting dopaminergic signals in the human ventral tegmental area
    Kimberlee D'Ardenne
    Department of Chemistry, Princeton University, Princeton, NJ 08544, USA
    Science 319:1264-7. 2008
    ..When monetary gains and losses were used, VTA BOLD responses reflected positive reward prediction errors modulated by the probability of winning. We detected no significant VTA BOLD response to nonrewarding events...
  66. pmc A meta-analytic investigation of the relationship between attentional bias and subjective craving in substance abuse
    Matt Field
    School of Psychology, University of Liverpool, Liverpool, UK
    Psychol Bull 135:589-607. 2009
    Theoretical models of addiction suggest that attentional bias for substance-related cues should be associated with self-reported craving...
  67. ncbi Saccade target selection and object recognition: evidence for a common attentional mechanism
    H Deubel
    Max Planck Institut für Psychologische Forschung, Munchen, Germany
    Vision Res 36:1827-37. 1996
    ..The results favor a model in which a single attentional mechanism selects objects for perceptual processing and recognition, and also provides the information necessary for motor action...
  68. pmc fMRI reactivity to high-calorie food pictures predicts short- and long-term outcome in a weight-loss program
    Donna L Murdaugh
    Department of Psychology, University of Alabama at Birmingham, Birmingham, AL 35294 1170, USA
    Neuroimage 59:2709-21. 2012
    Behavioral studies have suggested that food cues have stronger motivating effects in obese than in normal-weight individuals, which may be a risk factor underlying obesity...
  69. ncbi Are readers of our face readers of our minds? Dogs (Canis familiaris) show situation-dependent recognition of human's attention
    Márta Gácsi
    Comparative Ethology Research Group, Hungarian Academy of Sciences, Pázmany P 1 c, 1117, Budapest, Hungary
    Anim Cogn 7:144-53. 2004
    The ability of animals to use behavioral/facial cues in detection of human attention has been widely investigated...
  70. pmc Control of spatial and feature-based attention in frontoparietal cortex
    Adam S Greenberg
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurosci 30:14330-9. 2010
    ..These results suggest that the posterior parietal cortex is a common hub for the control of attention shifts but contains subpopulations of neurons with domain-specific tuning for cognitive control...
  71. ncbi Involuntary orienting to sound improves visual perception
    J J McDonald
    Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla 92093 0608, USA
    Nature 407:906-8. 2000
    ..These data show that the involuntary orienting of attention to sound enhances early perceptual processing of visual stimuli...
  72. ncbi Drug seeking becomes compulsive after prolonged cocaine self-administration
    Louk J M J Vanderschuren
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, UK
    Science 305:1017-9. 2004
    ....
  73. ncbi Infants' sensitivity to allophonic cues for word segmentation
    P W Jusczyk
    Department of Psychology, Johns Hopkins University, Baltimore, MD 21218, USA
    Percept Psychophys 61:1465-76. 1999
    A series of four experiments was conducted to determine whether English-learning infants can use allophonic cues to word boundaries to segment words from fluent speech...
  74. ncbi Activity associated with stream segregation in human auditory cortex is similar for spatial and pitch cues
    Stefan Schadwinkel
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, Germany
    Cereb Cortex 20:2863-73. 2010
    ..Examples for streaming cues are differences in frequency spectrum, pitch, or space, and potential neural correlates for streaming based on ..
  75. ncbi The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues
    Irene A Yun
    Ernest Gallo Clinic and Research Center, University of California, San Francisco, Emeryville, California 94608, USA
    J Neurosci 24:2923-33. 2004
    Reward-predictive cues exert powerful control over behavioral choice and may be a critical factor in drug addiction...
  76. ncbi Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues
    F Crestani
    Institute of Pharmacology, Swiss Federal Institute of Technology ETH and University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    Nat Neurosci 2:833-9. 1999
    ..mice represent a model of anxiety characterized by harm avoidance behavior and an explicit memory bias for threat cues, resulting in heightened sensitivity to negative associations...
  77. ncbi Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology
    Christian Grillon
    National Institute of Mental Health, Bethesda, Maryland, USA
    Biol Psychiatry 52:958-75. 2002
    ..Lacking a cue for threat, the organism cannot identify periods of danger and safety and remains in a chronic state of anxiety. Factors that may affect conditioning are discussed...
  78. ncbi Prefrontal-cingulate interactions in action monitoring
    W J Gehring
    Department of Psychology, University of Michigan, 525 East University Avenue, Ann Arbor, Michigan 48109 1109, USA
    Nat Neurosci 3:516-20. 2000
    ..Lateral prefrontal damage also affected corrective behavior. Thus the lateral prefrontal cortex seemed to interact with the anterior cingulate cortex in monitoring behavior and in guiding compensatory systems...
  79. ncbi Development of cue integration in human navigation
    Marko Nardini
    Centre for Brain and Cognitive Development, Birkbeck College, University of London, London, UK
    Curr Biol 18:689-93. 2008
    Mammalian navigation depends both on visual landmarks and on self-generated (e.g., vestibular and proprioceptive) cues that signal the organism's own movement [1-5]...
  80. ncbi The reinstatement model of drug relapse: history, methodology and major findings
    Yavin Shaham
    Behavioral Neuroscience Branch, NIDA IRP, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 168:3-20. 2003
    ..mediate reinstatement of heroin, cocaine and alcohol seeking by acute priming injections of drugs, drug-associated cues and environmental stressors are summarized...
  81. ncbi Bottomless bowls: why visual cues of portion size may influence intake
    Brian Wansink
    Applied Economics and Marketing, 110 Warren Hall, Cornell University, Ithaca, NY 14853 7801, USA
    Obes Res 13:93-100. 2005
    Using self-refilling soup bowls, this study examined whether visual cues related to portion size can influence intake volume without altering either estimated intake or satiation.
  82. ncbi The human amygdala in social judgment
    R Adolphs
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242, USA
    Nature 393:470-4. 1998
    ..The amygdala appears to be an important component of the neural systems that help retrieve socially relevant knowledge on the basis of facial appearance...
  83. ncbi Modulation of oscillatory neuronal synchronization by selective visual attention
    P Fries
    Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Building 49, Room 1B80, 9000 Rockville Pike, Bethesda, MD 20892 4415, USA
    Science 291:1560-3. 2001
    ..Because postsynaptic integration times are short, these localized changes in synchronization may serve to amplify behaviorally relevant signals in the cortex...
  84. ncbi Facial structure is a reliable cue of aggressive behavior
    Justin M Carré
    Department of Psychology, Brock University, St Catharines, Ontario, Canada
    Psychol Sci 20:1194-8. 2009
    ..These findings suggest that the facial width-to-height ratio may be a cue used to predict propensity for aggression in others...
  85. ncbi Antidepressant drug treatment modifies the neural processing of nonconscious threat cues
    Catherine J Harmer
    Department of Experimental Psychology, Warneford Hospital, Oxford, United Kingdom
    Biol Psychiatry 59:816-20. 2006
    ..Emotional disorders such as depression and anxiety have been associated with hyperactivity of the amygdala, but it is unknown whether antidepressant treatment directly affects amygdala responses to emotionally significant information...
  86. ncbi Probabilistic reasoning by neurons
    Tianming Yang
    Howard Hughes Medical Institute, Department of Physiology and Biophysics, National Primate Research Center, University of Washington, Box 357290, Seattle, Washington 98195 7290, USA
    Nature 447:1075-80. 2007
    ..Monkeys learned to combine probabilistic information from the shape combinations. Moreover, neurons in the parietal cortex reveal the addition and subtraction of probabilistic quantities that underlie decision-making on this task...
  87. ncbi Pictures of appetizing foods activate gustatory cortices for taste and reward
    W Kyle Simmons
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Cereb Cortex 15:1602-8. 2005
    ..Consistent with theories that ground knowledge in the modalities, these inferences arise as reenactments of modality-specific processing...
  88. ncbi Addiction: a disease of learning and memory
    Steven E Hyman
    Department of Neurobiology, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 162:1414-22. 2005
    ..use, the mechanisms that underlie the long persistence of relapse risk, and the mechanisms by which drug-associated cues come to control behavior...
  89. pmc Neural systems supporting lexical search guided by letter and semantic category cues: a self-paced overt response fMRI study of verbal fluency
    Rasmus M Birn
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD 20892, USA
    Neuroimage 49:1099-107. 2010
    ..We investigated verbal fluency to both letter and category cues in order to evaluate differential involvement of specific frontal and temporal lobe sites as a function of ..
  90. pmc 24-h smoking abstinence potentiates fMRI-BOLD activation to smoking cues in cerebral cortex and dorsal striatum
    F Joseph McClernon
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27708, USA
    Psychopharmacology (Berl) 204:25-35. 2009
    Exposure to smoking-related cues can trigger relapse in smokers attempting to maintain abstinence.
  91. pmc Fictive reward signals in the anterior cingulate cortex
    Benjamin Y Hayden
    Department of Neurobiology, Duke University School of Medicine, Center for Neuroeconomic Studies, Center for Cognitive Neuroscience, Duke University, Durham, NC 27701, USA
    Science 324:948-50. 2009
    ..We found that ACC neurons signal fictive reward information and use a coding scheme similar to that used to signal experienced outcomes. Thus, individual ACC neurons process both experienced and fictive rewards...
  92. ncbi Attention training for generalized social anxiety disorder
    Norman B Schmidt
    Department of Psychology, Florida State University, Tallahassee, FL 32306, USA
    J Abnorm Psychol 118:5-14. 2009
    Attentional bias toward negative social cues is thought to serve an etiological and/or maintaining role in social anxiety disorder (SAD)...
  93. ncbi Individual differences in emotion processing
    Stephan Hamann
    Department of Psychology, SUNY Stony Brook, Stony Brook, New York, NY 11794 2500, USA
    Curr Opin Neurobiol 14:233-8. 2004
    ..Analysis of individual differences provides a new window into the neurobiology of emotion processing that complements traditional approaches...
  94. ncbi Food deprivation and emotional reactions to food cues: implications for eating disorders
    D J Drobes
    NIMH Center for the Study of Emotion and Attention, University of Florida, Box 100165 HSC, Gainsville, FL 32610, USA
    Biol Psychol 57:153-77. 2001
    Two studies examined emotional responding to food cues. In experiment 1, normal college students were assigned to 0-, 6- or 24-h of food deprivation prior to presentations of standard emotional and food-related pictures...
  95. ncbi Body cues, not facial expressions, discriminate between intense positive and negative emotions
    Hillel Aviezer
    Department of Psychology, Princeton University, Princeton, NJ 08540, USA
    Science 338:1225-9. 2012
    ..These findings challenge standard models of emotion expression and highlight the role of the body in expressing and perceiving emotions...
  96. pmc D-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens
    Mary M Torregrossa
    Department of Psychiatry, Yale University, New Haven, Connecticut 06508, USA
    J Neurosci 30:10526-33. 2010
    Extinction therapy has been proposed as a method to reduce the motivational impact of drug-associated cues to prevent relapse. Cue extinction therapy, however, takes place in a novel context (e.g...
  97. ncbi Listener weighting of cues for lateral angle: the duplex theory of sound localization revisited
    Ewan A Macpherson
    Kresge Hearing Research Institute, University of Michigan, Ann Arbor 48109 0506, USA
    J Acoust Soc Am 111:2219-36. 2002
    ..the relative strengths of interaural time difference (ITD), interaural level difference (ILD), and spectral cues in determining the perceived lateral angle of wideband, low-pass, and high-pass noise bursts...
  98. ncbi Conscious and unconscious reward cues can affect a critical component of executive control
    Rémi L Capa
    Department of Cognitive Sciences, University of Liege, Belgium
    Exp Psychol 58:370-5. 2011
    ..study investigates whether updating an important function of executive control can be driven by unconscious reward cues. Participants had to memorize several numbers and update those numbers independently according to a sequence of ..
  99. ncbi Cues to intention: the role of movement information
    Luisa Sartori
    Dipartimento di Psicologia Generale, Universita di Padova, Padova, Italy
    Cognition 119:242-52. 2011
    Body movement provides a rich source of cues about other people's goals and intentions. In the present research, we investigate how well people can distinguish between different social intentions on the basis of movement information...
  100. ncbi Mammary odor cues and pheromones: mammalian infant-directed communication about maternal state, mammae, and milk
    Benoist Schaal
    Research Group in Developmental Ethology and Cognitive Psychology, Center for Taste and Smell Science, CNRS, Dijon, France
    Vitam Horm 83:83-136. 2010
    ..It appears that broadcasting chemical cues and/or signals from the mammae is a pan-mammalian reproductive strategy to pilot neonatal arousal, motivation and ..
  101. ncbi Slant from texture and disparity cues: optimal cue combination
    James M Hillis
    Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA
    J Vis 4:967-92. 2004
    How does the visual system combine information from different depth cues to estimate three-dimensional scene parameters? We tested a maximum-likelihood estimation (MLE) model of cue combination for perspective (texture) and binocular ..

Research Grants82

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  2. Genetic variation and regulatory networks: Mechanisms and complexity
    DANA PE ER; Fiscal Year: 2009
    ..These tools will be made publicly available, including a friendly graphical user interface and visualization. ..
  3. Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex
    Derek Toomre; Fiscal Year: 2009
    ..Consistent with the recovery act's goal, this funding will provide full-time summer employment for 4 undergraduate students and accelerate scientific achievement of the parent DP2 award...
  4. Brain Activation responses in adolescents with genetic predisposition to obesity
    Susan Carnell; Fiscal Year: 2011
    ..At 10:30 am, functional brain activity (fMRI) in response to visual high ED food cues (e.g. pizza), low ED food cues (e.g...
  5. Physiological role of PRDM16 in brown fat development and energy balance
    Patrick Seale; Fiscal Year: 2011
    ..that the adipogenic action of PRDIVI16 in committed myoblastic cells is compatible with the "real" environmental cues that control adipocyte differentiation in vivo...
  6. Neurobehavioral Correlates of Familial/genetic obesity risk in adolescents
    Susan Carnell; Fiscal Year: 2013
    ..At 10:30 am, functional brain activity (fMRI) in response to visual high ED food cues (e.g. pizza), low ED food cues (e.g...
  7. Global regulatory interactions in bacterial pathogenesis
    BRIAN AKERLEY; Fiscal Year: 2009
    ..The molecular interactions with the host that necessitate signal transduction by bacteria and the cues they utilize to respond appropriately are not well defined...
  8. Mechanisms of Sex Determination in Zebrafish
    JOHN HARVEY POSTLETHWAIT; Fiscal Year: 2013
    ..other genes in the network determine sex, and in some species, environmental factors such as temperature or social cues can bias sex development...
  9. Arcuate nucleus glutamatergic neurons modulate energy homeostasis
    Anthony N van den Pol; Fiscal Year: 2013
    ..In the fourth set of experiments, we ask whether arcuate glutamate neurons respond to long distance cues relating to energy homeostasis, particularly glucose and leptin...
  10. Neural Functioning of Feeding Centers in Obese Youth
    ROBERT STANLEY SHERWIN; Fiscal Year: 2013
    ..3- Functional connectivity between brain regions of the reward system implicated in the response to specific food cues are altered in the obese adolescents and this is related to hyperinsulinemia/insulin resistance...
  11. Human middle-ear imaging, physiology, and biomechanics
    CHARLES RICHARD STEELE; Fiscal Year: 2013
    ..of hearing in the speech frequency range, and not in the higher frequencies where important sound localization cues are known to reside...
  12. Interplay Between Tissue Architecture and Nuclear Organization in the DNA Damage
    Pierre Alexandre Vidi; Fiscal Year: 2013
    ..Mechanotransduction or biochemical signaling via hemidesmosomal integrins may convey extracellular cues to the cell nucleus, leading to changes in nuclear organization affecting the DDR...
  13. Role of leptin-mediated PI3 Kinase signaling on reproductive control
    Carol Fuzeti Elias; Fiscal Year: 2013
    ..Our main objective is to add knowledge on how the brain integrates nutritional cues to regulate many parameters of the female reproductive physiology...
  14. Therapeutic Approaches for Extinction of Conditioned Drug Reward
    Gary B Kaplan; Fiscal Year: 2013
    ..During drug-taking, individuals are exposed to environmental cues or contexts where drugs of abuse are administered...
  15. Olfactory Circuits for Reproduction and Reward
    James A Cherry; Fiscal Year: 2013
    ..olfactory systems in the mouse, we will compare the involvement of each system in regulating responses to olfactory cues that control sexual motivation and reward...
  16. Integrating stress MAP kinase signaling with DNA replication origin licensing
    Jeanette Gowen Cook; Fiscal Year: 2013
    ..long-term goal is to determine precisely how origin licensing proteins are regulated by intracellular cell cycle cues and by extracellular signaling pathways...
  17. Safety signal learning in Rhesus monkeys following early life stressChallenge Ar
    MICHAEL NMN DAVIS; Fiscal Year: 2010
    ..Three cues are used in the form AX+/BX-, where cues A and X in compound (e.g...
  18. Role of estrogen-related receptors in cardiac and skeletal muscle
    Janice M Huss; Fiscal Year: 2010
    ..of energy substrates in heart and skeletal muscle is regulated by developmental, physiological, and environmental cues that signal coordinated changes in the levels of enzymes involved these processes...
  19. Proteomic signatures of an early life asthma-protective exposure
    Serrine S Lau; Fiscal Year: 2010
    ..exposure and disease status provide clues for the identification of molecular pathways activated by environmental cues and which are involved in conferring protection from asthma...
  20. Germ Cell Migration in Drosophila.
    Ruth Lehmann; Fiscal Year: 2012
    ..During directed cell migration, motile cells are guided along a particular path, they recognize guidance cues and translate them into directed movement...
  21. Lipid glyceryl ester homeostasis in macrophages and perturbation by environmental
    Matthew K Ross; Fiscal Year: 2012
    ..the vessel wall express CB1 and CB2, and 2AG biosynthesis is augmented when macrophages are stimulated by external cues, it is unclear how these opposing signaling pathways are integrated to influence atherosclerosis development...
  22. PERIPHERAL AND CENTRAL INTERACTIONS IN ENERGY BALANCE
    Barbara B Kahn; Fiscal Year: 2010
    ..genetic, physiological, biochemical, and neuroanatomic techniques to investigate the actions of critical metabolic cues including leptin, ghrelin, and nutrient sensing in the regulation of food intake, energy expenditure, and body ..
  23. Cyclic AMP Signaling in Pseudomonas aeruginosa Virulence
    Matthew C Wolfgang; Fiscal Year: 2011
    ..aeruginosa virulence program by producing cAMP in response to host cues. CyaB activity is positively regulated by components of the P...
  24. TNF-Mediated Tumor Promotion: The Role of Vascular Leukocytes
    Pampee P Young; Fiscal Year: 2011
    ..Generation of vascular leukocytes is likely modulated by cues from the tumor microenvironment. The mechanism of their generation is not known...
  25. Tick Midgut Proteins Critical for Borrelia Transmission
    Sukanya Narasimhan; Fiscal Year: 2010
    ..The commencement of feeding, provides cues to the spirochete that trigger active growth and replication of the bacterium, as it prepares to migrate from the ..
  26. ROLE OF ENHANCERS REGULATING RENIN GENE EXPRESSION
    CURT DANIEL SIGMUND; Fiscal Year: 2013
    ..in controlling the cell- and tissue-specificity of expression and the transcriptional responses to physiological cues. We will build upon the progress and major scientific achievements ofthe current budget period to dramatically ..
  27. Analysis of the tumor suppressor gene Tsc1 in motor neuron patterning
    Onanong Chivatakarn; Fiscal Year: 2013
    ..the identification of the GrL/TSC1 mutation in my screen, and the recent observation that inhibitory axon guidance cues negatively regulate the mTOR pathway...
  28. TRANSCRIPTIONAL REPRESSION BY POLYCOMB GROUP PRODUCTS
    Jeffrey A Simon; Fiscal Year: 2012
    ..Thus, PcG proteins provide molecular memory of spatial cues present in early embryos...
  29. Antigen receptor inputs: linking structural, molecular, and cellular responses
    Jonathan P Schneck; Fiscal Year: 2012
    ..The five projects cover a range of stimuli, cues and outcomes that result in various states of T cell activation or unresponsiveness, from the initial events of ..
  30. In vivo targeted gene silencing, a novel method
    WILLIAM ANTHONY TRUITT; Fiscal Year: 2012
    ..In a recent animal study using rats, we described a neural circuit that regulates emotional responses to social cues and may be related to deficits in social processing observed with spectrum disorders...
  31. Dissecting the role of one neuronal RhoGEF amongst many: the Kalirin-7 null mouse
    Richard E Mains; Fiscal Year: 2012
    ..The number and shape of dendritic spines respond to developmental cues, environmental stimuli and hormonal changes...
  32. Lung and bone marrow crosstalk during a respiratory infection
    CAROLINA B LOPEZ; Fiscal Year: 2010
    ..These primed cells perform effectively when encountering pathogen cues in the lung...
  33. Role of Biophysical Cues in the Pathogenesis of Glaucoma
    Paul Russell; Fiscal Year: 2013
    ..Numerous reports have shown that cells respond to biophysical cues in the micro- to nano-scale range...
  34. Germ Cell Migration in Drosophila.
    Ruth Lehmann; Fiscal Year: 2013
    ..During directed cell migration, motile cells are guided along a particular path, they recognize guidance cues and translate them into directed movement...
  35. Prenatal stress and epigenetic programming of the HPA axis and autonomic balance
    Rosalind J Wright; Fiscal Year: 2013
    ..During pregnancy, maternal experiences and conditions, including stress, expose the fetus to hormonal and metabolic cues that may induce 'fetal programming'...
  36. Mutational Cloning in Familial Dementia and Alzheimers Disease
    Wendy H Raskind; Fiscal Year: 2010
    ..predicted effect of the mutation, existence of animal models, involvement in human diseases, and other cues from the literature...
  37. Genome-wide Identification of Immediate Early Genes in Insects
    Anandasankar Ray; Fiscal Year: 2012
    ..Furthermore, in disease vectors such as Anopheles gambiae that use chemical cues to identify their hosts, an understanding of evolutionarily conserved genes that function in neural circuits that ..
  38. Cardiac Regeneration through Growth Factor Eluting Microrod Scaffolds
    Paul H Goldspink; Fiscal Year: 2013
    ..MRS) to not only deliver the native, rapidly degradable MGF, but also provide local mechanical and topographic cues necessary for proper cellular connectivity and differentiation...
  39. A Mindfulness-Based Approach to the Treatment of Obesity and Diabetes
    Carla K Miller; Fiscal Year: 2010
    ..to treatment that focuses on mindful meditation, mindful eating, and mindful practice of body awareness and satiety cues or to a standard 10-week, group-based intervention that meets the nutritional standards of care for people with ..
  40. CIRCUITS MEDIATING BEHAVIORAL CONSEQUENCES OF STEROID SENSATION
    Timothy E Holy; Fiscal Year: 2013
    ..or physiological responses mediated by the accessory olfactory system frequently involve integration of multiple cues;in particular, there are several examples in which male-derived stimuli act in opposition with female-derived ..
  41. Developmental Physiology of Ciliated Epithelia
    CHRISTOPHER ROBERT KINTNER; Fiscal Year: 2012
    ..These experiments will dissect the patterning cues that orient ciliated cells when they form, and the role of flow in refining ciliated cell orientation...
  42. Inflammatory Cytokines Link NF-kappaB with Bim Degradation and Metastasis
    Marty W Mayo; Fiscal Year: 2012
    ..To understand better how NSCLC cells resist apoptotic cues, we have characterized the molecular pathways used by NF-?B to block apoptosis...
  43. Novel Mechanisms Regulating the Adipocyte-Brain Hepatocyte Axis
    Philipp E Scherer; Fiscal Year: 2013
    The central integration of peripheral metabolic cues that lead to coordinated control of liver metabolism is very important, yet not well understood...
  44. Calcification and Vascular Cell Differentiation
    Cecilia M Giachelli; Fiscal Year: 2013
    ..our overall hypothesis is that SMCs undergo lineage reprogramming in response to disease-specific, procalcific cues that convergeon a common downstream mediator, Runx2 (Figure 1) via the activation of Erk1/2...
  45. A novel and powerful C. elegans behavioral model of addiction
    Eric A Engleman; Fiscal Year: 2013
    ..In addition, we have recently reported that C. elegans display a conditioned preference for cues (salts) that had previously been paired with cocaine or methamphetamine which is analogous to findings in mammalian ..
  46. Cerebrospinal fluid proteome mediated signaling in the developing CNS
    Maria Lehtinen; Fiscal Year: 2011
    ..Art McMorris, I investigated extrinsic cues triggering cAMP signaling in glia. As an undergraduate research fellow at Rockefeller University in Dr...
  47. Cerebrospinal fluid proteome mediated signaling in the developing CNS
    Maria Lehtinen; Fiscal Year: 2013
    ..Art McMorris, I investigated extrinsic cues triggering cAMP signaling in glia. As an undergraduate research fellow at Rockefeller University in Dr...
  48. Effect of Baclofen on Alcohol Cue-Elicited Urges to Drink and Smoke
    GEORGE ANTHONY KENNA; Fiscal Year: 2011
    ..alcoholic cues. Specifically, this R03 SOAR sub-study project will be a 1-day double-blind, placebo-controlled, between-subject ..
  49. MODULATION OF ALCOHOL REINFORCEMENT
    Christopher L Cunningham; Fiscal Year: 2012
    ..in either the acquisition or the expression of conditioned place preference using both tactile and visual-spatial cues. Brain areas of interest include: ventral tegmental area, amygdala, nucleus accumbens, bed nucleus of the stria ..
  50. Role of Protein Kinase D in Skin Epithelia
    Soosan Ghazizadeh; Fiscal Year: 2012
    ..that differentiated keratinocytes possess an inducible proliferative capacity that is activated in response to cues from the microenvironment...
  51. Treatment Implications of Trauma Memory Modulation for PTSD & Alcohol Dependence
    Michael E Saladin; Fiscal Year: 2010
    ..blocker propranolol on emotional distress, craving and other responses to trauma- and alcohol-related cues and on alcohol use and PTSD symptoms...
  52. CRF and Stress Modulation of Phasic Dopamine Release and Behavior
    MATTHEW J WANAT; Fiscal Year: 2013
    ..this K99/R00 'Pathway to Independence Award'proposal is to assess how stress-related peptides, aversive cues, and stressful stimuli directly affect phasic dopamine release, which is the pattern of dopamine release directly ..
  53. DETERMINATION OF NEURONAL FATES IN VISUAL CORTEX
    Susan K McConnell; Fiscal Year: 2013
    ..we will ascertain whether and over what period of time a young cortical neuron can respond to local fate- inducing cues and alter its normal layer-specific identity, as assessed by its dendritic morphology, local and long distance ..
  54. Control of developmental timing and body size in Drosophila
    MICHAEL BRENDAN O'CONNOR; Fiscal Year: 2013
    ..This transition is also controlled by a neuropeptide signal in conjunction with nutritional and metabolic cues, although little is presently known about how these signals are integrated to time the transition appropriately...
  55. Short-term responses to temperature changes in Escherichia coli
    Christine A White Ziegler; Fiscal Year: 2010
    ..Bacteria have the ability to sense a multitude of environmental stimuli and use these cues to regulate gene expression and adapt accordingly...
  56. Molecular Determinants of Tumor Progression in A Steatolic Liver Microenvironment
    Harold L Moses; Fiscal Year: 2013
    ..that MMP-mediated proteolysis of cytokines, chemokines, and/or adipokines establishes microenvironmental cues that influence the survival and establishment of metastatic cancer cells in the steatotic liver...
  57. Physiologic Regulation of Hematopoiesis by Notch
    Nadia Carlesso; Fiscal Year: 2011
    ..Hypothesis. Based on these results, we propose a model in which BM microenvironmental cues signal to hematopoietic cells and their cell cycle machinery via Notch signaling...
  58. The Role of PtdIns-5-P in Cell Function and Signaling
    LUCIA RAMEH-PLANT; Fiscal Year: 2012
    ..PI-5-P has properties of a signaling molecule - its levels are low and can be rapidly regulated by extracellular cues. Remarkably, PI-5-P levels are up-regulated upon bacterial invasion of host cells, due to the activity of the ..
  59. Translational studies of the Platelet Specific Receptor Trem Like Transcript (TLT
    A Valance Washington; Fiscal Year: 2013
    ..and possibly leukocytes, thereby potentiating their ability to respond to both hematological and immunological cues. To test this hypothesis we have developed the following three specific aims...
  60. Hypocretin and Locus Ceruleus Interactions in Zebrafish Development and Behavior
    Grigorios Oikonomou; Fiscal Year: 2012
    ..To test the hypothesis that LC neurons provide cues necessary for the normal extension and arborization of Hcrt projections, the LC will be ablated and silenced...
  61. Regulation of tubulogenesis in the Drosophila ovary
    Celeste A Berg; Fiscal Year: 2012
    ..and move in a directed fashion, less is known about how sheets of cells respond to environmental or genetic cues. This lab has developed the tools to tackle this important question...
  62. Human Blood-Brain Barrier Model for CNS Drug Translation
    Eric V Shusta; Fiscal Year: 2010
    ..cells having well developed tight junctions, characteristic transporter expression, and capability to respond to cues provided by co-cultured neural cells. As such, we have approximated human BBB function in the culture dish...
  63. Polarization and directed cell movements in engineered cellular environments
    Deborah E Leckband; Fiscal Year: 2010
    ..Soft lithography enables the establishment of defined fields of adhesive and chemotactic cues in ways that are not accessible in vivo or in standard tissue culture format...
  64. Neuropharmacology of Cue-Induced Nicotine Relapse
    Xiu Liu; Fiscal Year: 2009
    ..of alcoholic beverages, being with friends who smoke, drinking coffee, reading the morning newspaper) become cues that elicit subjective states that can trigger craving, drug-seeking behavior and the resumption of nicotine use...
  65. "Smart" Materials to Engineer a More Complete Stem Cell Niche
    Adam Engler; Fiscal Year: 2009
    ..However, these cues have typically been studied as isolated stimuli where no single cue, whether a growth factor or an ECM property, ..
  66. Cues from touch to aid posture and gait in individuals with Parkinson's disease
    Ely Rabin; Fiscal Year: 2010
    ..Most interventions involving use of visual or auditory sensory cues to improve posture and gait do not carry over from the clinic to everyday living, and performance returns to pre-..
  67. Wide-bandwidth open canal hearing aid for better multitalker speech understanding
    Sunil Puria; Fiscal Year: 2009
    ..The third is to place a wide-bandwidth microphone in the ear canal to capture the pinna diffraction cues, in a similar manner to the functioning of a normal ear...
  68. Motivational control of goal-directed actions and habits
    Brian J Wiltgen; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): The goal of this project is to examine the motivational effects of reward cues on habitual responding...
  69. Novel Static Screen Volumetric 3D Display for Medical Image Visualization
    Jason Geng; Fiscal Year: 2010
    ..images are inherently of 3D nature, yet all conventional displays use flat 2D screens that lack important depth cues. While rendering software using 2D display monitors are quite effective in presenting 3D aspects of the imaging ..
  70. Impact of Emotional Cues on Family Violence
    GORDON DAHL; Fiscal Year: 2009
    ..We will also use the NIBRS data to study the effect of unexpected emotional cues on family violence...
  71. Using light to increase visual and perceptual cues and decrease falls risk
    MARIANA FIGUEIRO; Fiscal Year: 2010
    ..help provide visual information about the architectural space to older adults b) distinct vertical and horizontal cues, which will provide older adults with the perception of veridical spatial orientation and c) horizontal cues, which ..
  72. PHARMACOTHERAPY OF CUE INDUCED COCAINE CRAVING
    S Berger; Fiscal Year: 2000
    The ability of cues previously associated with cocaine to trigger craving, even after long intervals of abstinence, has been hypothesized to be an important determinant of relapse...
  73. Sensitivity to spectral cues in infant speech perception
    CHRISTIAN EDMUND STILP; Fiscal Year: 2010
    ..provided by applicant): The proposed research will examine infants'sensitivity to multiple spectral cues in speech perception. Speech is a complex signal, with numerous acoustic cues for every consonant and vowel...
  74. Social attachment and reproductive regulation
    HEATHER ELIZABETH WATTS; Fiscal Year: 2010
    This project will explore the neural processing of social cues from potential mates and the neuroendocrine mechanisms by which these social cues modulate reproductive physiology...
  75. A VISUAL CUE MODEL TO INVESTIGATE COCAINE REWARD
    Chana Akins; Fiscal Year: 2004
    ..This application will help her to accomplish those goals. Research: Distal cues that elicit approach to drugs are often visual cues...
  76. The role of phasic dopamine release in cue-evoked motivated behaviors
    MATTHEW J WANAT; Fiscal Year: 2010
    ..In particular, drug-related cues can promote motivated drug seeking through activation of the mesocorticolimbic dopamine system...
  77. Kidney vascularization: semaphorin-mediated mechanisms.
    Alda Tufro; Fiscal Year: 2006
    ..Other guidance cues are necessarily involved to modulate vascular growth. The nature of these guidance cues is unknown...
  78. Cortical Sensitivity to Acoustic Cues for Sound Location
    EWAN MACPHERSON; Fiscal Year: 2006
    ..cat preparation, how these representations are derived from units' sensitivities to various individual spatial cues and how these sensitivities vary among cortical areas...
  79. Extinction of Limbic Activation to "Unseen" Cocaine Cues
    Anna Rose Childress; Fiscal Year: 2010
    ..for drug addiction: Cocaine patients show a remarkable persistence of desire and arousal to cocaine cues, months or even years after the last dose of drug...
  80. Relationship Between Psychoacoustic Thresholds and Speech Recognition for Aided L
    MARC A BRENNAN; Fiscal Year: 2010
    ..User benefit depends upon the ability of compression hearing aids to provide the acoustic cues necessary for speech recognition...
  81. Emotional and attentional biases to drug and trauma cues in addiction with PTSD
    Estate Sokhadze; Fiscal Year: 2006
    ..on mental tasks to study the role of attentional biases in responses to drug- and traumatic stress-related cues in individuals with substance use disorder (SUD) with comorbid posttraumatic stress disorder (PTSD)...
  82. The Influence of Emotion Regulation on the Neural Systems of Reward Processing
    Mauricio Delgado; Fiscal Year: 2007
    ..consumption and immediate rewards, a risk-taking individual is constantly presented with salient conditioned cues representing risk-taking opportunities...