antisocial personality disorder

Summary

Summary: A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994)

Top Publications

  1. ncbi White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder
    Frederick Sundram
    King s College London, Institute of Psychiatry, Department of Forensic and Neurodevelopmental Science, London, UK Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Cortex 48:216-29. 2012
  2. pmc Reduced prefrontal connectivity in psychopathy
    Julian C Motzkin
    Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    J Neurosci 31:17348-57. 2011
  3. ncbi Antisocial behavior from a developmental psychopathology perspective
    Paul J Frick
    Department of Psychology, University of New Orleans, 2001 Geology and Psychology Building, New Orleans, LA 70148, USA
    Dev Psychopathol 21:1111-31. 2009
  4. ncbi Female and male antisocial trajectories: from childhood origins to adult outcomes
    Candice L Odgers
    Department of Psychology and Social Behavior, University of California Irvine, Irvine, CA92697 7085, USA
    Dev Psychopathol 20:673-716. 2008
  5. ncbi Volumetric structural brain abnormalities in men with schizophrenia or antisocial personality disorder
    Ian Barkataki
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Behav Brain Res 169:239-47. 2006
  6. pmc Attention moderates the fearlessness of psychopathic offenders
    Joseph P Newman
    Department of Psychology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Biol Psychiatry 67:66-70. 2010
  7. ncbi Not just fear and sadness: meta-analytic evidence of pervasive emotion recognition deficits for facial and vocal expressions in psychopathy
    Amy Dawel
    Department of Psychology buiding 39, The Australian National University, Canberra, ACT 0200, Australia
    Neurosci Biobehav Rev 36:2288-304. 2012
  8. ncbi Deficient fear conditioning in psychopathy: a functional magnetic resonance imaging study
    Niels Birbaumer
    Institute of Medical Psychology and Behavioral Neurobiology and Section of Experimental Resonance Imaging of the CNS, Department of Neuroradiology, University of Tubingen, Tubingen, Germany
    Arch Gen Psychiatry 62:799-805. 2005
  9. ncbi Evidence for substantial genetic risk for psychopathy in 7-year-olds
    Essi Viding
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 46:592-7. 2005
  10. ncbi Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits
    Alice P Jones
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Department of Forensic Mental Health, Institute of Psychiatry, King s College London, UK
    Am J Psychiatry 166:95-102. 2009

Detail Information

Publications347 found, 100 shown here

  1. ncbi White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder
    Frederick Sundram
    King s College London, Institute of Psychiatry, Department of Forensic and Neurodevelopmental Science, London, UK Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Cortex 48:216-29. 2012
    b>Antisocial personality disorder (ASPD) and psychopathy involve significant interpersonal and behavioural impairments...
  2. pmc Reduced prefrontal connectivity in psychopathy
    Julian C Motzkin
    Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    J Neurosci 31:17348-57. 2011
    ..Together, these data converge to implicate diminished vmPFC connectivity as a characteristic neurobiological feature of psychopathy...
  3. ncbi Antisocial behavior from a developmental psychopathology perspective
    Paul J Frick
    Department of Psychology, University of New Orleans, 2001 Geology and Psychology Building, New Orleans, LA 70148, USA
    Dev Psychopathol 21:1111-31. 2009
    ..Finally, we discuss how this development model can be used to enhance existing interventions for antisocial individuals...
  4. ncbi Female and male antisocial trajectories: from childhood origins to adult outcomes
    Candice L Odgers
    Department of Psychology and Social Behavior, University of California Irvine, Irvine, CA92697 7085, USA
    Dev Psychopathol 20:673-716. 2008
    ..Implications for theory, research, and practice are discussed...
  5. ncbi Volumetric structural brain abnormalities in men with schizophrenia or antisocial personality disorder
    Ian Barkataki
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Behav Brain Res 169:239-47. 2006
    Brain abnormalities are found in association with antisocial personality disorder and schizophrenia, the two mental disorders most implicated in violent behaviour...
  6. pmc Attention moderates the fearlessness of psychopathic offenders
    Joseph P Newman
    Department of Psychology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Biol Psychiatry 67:66-70. 2010
    ..An alternative view is that psychopathy involves an attention-related deficit that undermines the processing of peripheral information, including fear stimuli...
  7. ncbi Not just fear and sadness: meta-analytic evidence of pervasive emotion recognition deficits for facial and vocal expressions in psychopathy
    Amy Dawel
    Department of Psychology buiding 39, The Australian National University, Canberra, ACT 0200, Australia
    Neurosci Biobehav Rev 36:2288-304. 2012
    ..We discuss limitations of the available data that restrict the ability of meta-analysis to consider the influence of age and separate the sub-factors of psychopathy, highlighting important directions for future research...
  8. ncbi Deficient fear conditioning in psychopathy: a functional magnetic resonance imaging study
    Niels Birbaumer
    Institute of Medical Psychology and Behavioral Neurobiology and Section of Experimental Resonance Imaging of the CNS, Department of Neuroradiology, University of Tubingen, Tubingen, Germany
    Arch Gen Psychiatry 62:799-805. 2005
    Psychopaths belong to a larger group of persons with antisocial personality disorder and are characterized by an inability to have emotional involvement and by the repeated violation of the rights of others...
  9. ncbi Evidence for substantial genetic risk for psychopathy in 7-year-olds
    Essi Viding
    Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 46:592-7. 2005
    ..We report here the first twin study of high levels of psychopathic tendencies in young children...
  10. ncbi Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits
    Alice P Jones
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Department of Forensic Mental Health, Institute of Psychiatry, King s College London, UK
    Am J Psychiatry 166:95-102. 2009
    ..Using functional MRI, the authors evaluated differences in neural response to emotional stimuli between boys with conduct problems and elevated levels of callous-unemotional traits and comparison boys...
  11. ncbi Psychopathy as a disorder of the moral brain: fronto-temporo-limbic grey matter reductions demonstrated by voxel-based morphometry
    Ricardo de Oliveira-Souza
    Cognitive and Behavioral Neuroscience Unit, LABS D Or Hospital Network, Rio de Janeiro, Brazil
    Neuroimage 40:1202-13. 2008
    ..The pattern of grey matter reductions in patients with high psychopathy scores comprised a distributed fronto-temporal network which plays a critical role in moral sensibility and behavior...
  12. pmc Deficits in facial affect recognition among antisocial populations: a meta-analysis
    Abigail A Marsh
    National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Neurosci Biobehav Rev 32:454-65. 2008
    ..This impairment cannot be attributed solely to task difficulty. These results suggest dysfunction among antisocial individuals in specified neural substrates, namely the amygdala, involved in processing fearful facial affect...
  13. ncbi Role of genotype in the cycle of violence in maltreated children
    Avshalom Caspi
    Medical Research Council Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College, London SE5 8AF, UK
    Science 297:851-4. 2002
    ..These findings may partly explain why not all victims of maltreatment grow up to victimize others, and they provide epidemiological evidence that genotypes can moderate children's sensitivity to environmental insults...
  14. ncbi Neural abnormalities in early-onset and adolescence-onset conduct disorder
    Luca Passamonti
    Cognition and Brain Sciences Unit, Medical Research Council, University of Cambridge, Cambridge, England
    Arch Gen Psychiatry 67:729-38. 2010
    ....
  15. pmc Aberrant paralimbic gray matter in criminal psychopathy
    Elsa Ermer
    Department of Psychology, University of New Mexico, The MIND Research Network, Albuquerque, NM 87123, USA
    J Abnorm Psychol 121:649-58. 2012
    ..The consistent identification of paralimbic cortex and limbic structures in psychopathy across diverse methodologies strengthens the interpretation that these regions are crucial for understanding neural dysfunction in psychopathy...
  16. pmc Serotonin transporter gene associations with psychopathic traits in youth vary as a function of socioeconomic resources
    Naomi Sadeh
    Department of Psychology, University of Illinois at Urbana Champaign, 603 East Daniel Street, Champaign, IL 61820, USA
    J Abnorm Psychol 119:604-9. 2010
    ..These studies provide preliminary results that the l/l genotype confers risk for the emotional deficits and predatory interpersonal traits associated with psychopathy among youths raised in disadvantaged environments...
  17. pmc Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning
    Elizabeth C Finger
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Arch Gen Psychiatry 65:586-94. 2008
    ....
  18. pmc Developmental trajectories of male physical violence and theft: relations to neurocognitive performance
    Edward D Barker
    Research Unit on Children s Psychosocial Maladjustment, Universite de Montreal, Montreal, Quebec, Canada
    Arch Gen Psychiatry 64:592-9. 2007
    ..However, studies examining this association tend to aggregate a variety of problem behaviors that may be differently affected by neurocognitive deficits...
  19. ncbi The amygdala and ventromedial prefrontal cortex in morality and psychopathy
    R J R Blair
    Mood and Anxiety Program, National Institute of Mental Health, Department of Health and Human Services, 15K North Drive, MSC 2670, Bethesda, MD 20892, USA
    Trends Cogn Sci 11:387-92. 2007
    ..In psychopathy, dysfunction in these structures means that care-based moral reasoning is compromised and the risk that antisocial behavior is used instrumentally to achieve goals is increased...
  20. ncbi Impaired reversal but intact acquisition: probabilistic response reversal deficits in adult individuals with psychopathy
    Salima Budhani
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    J Abnorm Psychol 115:552-8. 2006
    ..Results are discussed with reference to current models of the development of psychopathy...
  21. ncbi Sex differences in psychopathy and antisocial personality disorder. A review and integration
    Ellison M Cale
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Clin Psychol Rev 22:1179-207. 2002
    Although the correlates and causes of psychopathy and antisocial personality disorder (ASPD) have been the subject of extensive investigation, researchers in this area have until recently focused almost exclusively on males...
  22. ncbi Psychopathy, antisocial personality, and suicide risk
    E Verona
    Department of Psychology, Florida State University, USA
    J Abnorm Psychol 110:462-70. 2001
    ..using the PCL-R and DSM-III-R and DSM-IV criteria (American Psychiatric Association, 1987, 1994) for antisocial personality disorder (APD), and they completed A. Tellegen's (1982) Multidimensional Personality Questionnaire (MPQ)...
  23. ncbi Morphological alterations in the prefrontal cortex and the amygdala in unsuccessful psychopaths
    Yaling Yang
    Laboratory of Neuroimaging, University of California Los Angeles, Los Angeles, CA 90095, USA
    J Abnorm Psychol 119:546-54. 2010
    ....
  24. ncbi Etiologic connections among substance dependence, antisocial behavior, and personality: modeling the externalizing spectrum
    Robert F Krueger
    Department of Psychology, University of Minnesota, Minneapolis 55455 0344, USA
    J Abnorm Psychol 111:411-24. 2002
    ..These results reconcile evidence for general and specific causal factors within the externalizing spectrum and offer the externalizing factor as a novel target for future research...
  25. ncbi Turning a deaf ear to fear: impaired recognition of vocal affect in psychopathic individuals
    R James R Blair
    Unit on Affective Cognitive Neuroscience, Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, Maryland 20892 2670, USA
    J Abnorm Psychol 111:682-6. 2002
    ..The results indicated that psychopathic inmates were particularly impaired in the recognition of fearful vocal affect. These results are interpreted with reference to the low-fear and violence inhibition mechanism models of psychopathy...
  26. ncbi Applying a cognitive neuroscience perspective to the disorder of psychopathy
    R J R Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    Dev Psychopathol 17:865-91. 2005
    ..Some directions for future work are considered...
  27. ncbi Brain anatomy of persistent violent offenders: more rather than less
    Jari Tiihonen
    Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Kuopio, Kuopio, Finland
    Psychiatry Res 163:201-12. 2008
    ..We compared regional brain volumes of 26 persistently violent offenders with antisocial personality disorder and substance dependence and 25 healthy men using magnetic resonance imaging volumetry and voxel-..
  28. ncbi Structural models of psychopathy
    Robert D Hare
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC V6T 1Z4, Canada
    Curr Psychiatry Rep 7:57-64. 2005
    ..We also report new evidence that psychopathy and its factors are dimensional in nature, perhaps extreme variants of normal personality traits and behaviors...
  29. ncbi Functional differences among those high and low on a trait measure of psychopathy
    Heather L Gordon
    Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
    Biol Psychiatry 56:516-21. 2004
    ..The aim of this study was to elucidate the relation of emotion and cognition to individual differences on a standard psychopathy personality inventory (PPI) among a nonpsychiatric population...
  30. ncbi Gray matter changes in right superior temporal gyrus in criminal psychopaths. Evidence from voxel-based morphometry
    Jürgen L Müller
    Department of Forensic Psychiatry and Psychotherapy, University of Gottingen, Von Siebold Str 5, D 37075 Gottingen, Germany
    Psychiatry Res 163:213-22. 2008
    Psychopathy" according to the PCL-R describes a specific subgroup of antisocial personality disorder with a high risk for criminal relapses...
  31. pmc Investigating the neural correlates of psychopathy: a critical review
    M Koenigs
    Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
    Mol Psychiatry 16:792-9. 2011
    ..We propose several strategies for resolving these methodological issues in future studies, with the goal of fostering further progress in the identification of the neural correlates of psychopathy...
  32. ncbi Psychopathic traits in females and males across the globe
    Craig S Neumann
    University of North Texas, Denton, Texas 76203, USA
    Behav Sci Law 30:557-74. 2012
    ....
  33. ncbi The reliability, stability, and predictive utility of the self-report version of the Antisocial Process Screening Device
    Luna C Munoz
    Orebro University, Orebro, Sweden
    Scand J Psychol 48:299-312. 2007
    ..One major weakness of the self-report ratings was the low internal consistency of the subscales, which were much lower than the internal consistency found on the parent report version of the scale...
  34. ncbi Altered connections on the road to psychopathy
    M C Craig
    Section of Brain Maturation, Institute of Psychiatry, De Crespigny Park, London, UK
    Mol Psychiatry 14:946-53, 907. 2009
    ..Our findings remained significant. Taken together, these results suggest that abnormalities in a specific amygdala-OFC limbic network underpin the neurobiological basis of psychopathy...
  35. pmc Increased volume of the striatum in psychopathic individuals
    Andrea L Glenn
    Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Biol Psychiatry 67:52-8. 2010
    ..Few studies have explored whether differences are present in the striatum of antisocial individuals. Here, we examine the structure of the striatum in relation to psychopathy...
  36. ncbi Heritability of antisocial behaviour at 9: do callous-unemotional traits matter?
    Essi Viding
    Department of Psychology, University College London, and SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Dev Sci 11:17-22. 2008
    ..The heritability difference was even more pronounced in magnitude when hyperactive symptoms were controlled. CU traits thus appear to index one valid way of sub-typing children with early-onset AB...
  37. ncbi Genetic and neurocognitive contributions to the development of psychopathy
    Essi Viding
    Division of Psychology and Language Sciences, University College London, Gower Street, London WC1 6BT, United Kingdom
    Dev Psychopathol 24:969-83. 2012
    ..By contrast, preliminary evidence suggests that enhancing positive parenting and parental involvement, as well as applying consistent rewards may represent more promising intervention approaches...
  38. ncbi The antisocial brain: psychopathy matters
    Sarah Gregory
    Forensic and Neurodevelopmental Sciences Department, Institute of Psychiatry, King s College London, England, UK
    Arch Gen Psychiatry 69:962-72. 2012
    ..The population of men who display persistent antisocial and violent behavior is heterogeneous. Callous-unemotional traits in childhood and psychopathic traits in adulthood characterize a distinct subgroup...
  39. pmc The psychopath magnetized: insights from brain imaging
    Nathaniel E Anderson
    MIND Research Network, 1101 Yale Blvd NE, Albuquerque, NM 87106, USA
    Trends Cogn Sci 16:52-60. 2012
    ..We discuss these findings in the context of extant theories of psychopathy and highlight the potential legal and policy implications of this body of work...
  40. pmc Neural foundations to moral reasoning and antisocial behavior
    Adrian Raine
    Department of Psychology and Neuroscience Program, University of Southern California, USA
    Soc Cogn Affect Neurosci 1:203-13. 2006
    ..While this neurobiological predisposition is likely only one of several biosocial processes involved in the etiology of antisocial behavior, it raises significant moral issues for the legal system and neuroethics...
  41. pmc Localization of deformations within the amygdala in individuals with psychopathy
    Yaling Yang
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Arch Gen Psychiatry 66:986-94. 2009
    ....
  42. ncbi Substance abuse hinders desistance in young adults' antisocial behavior
    Andrea M Hussong
    University of North Carolina at Chapel Hill, 27599 3270, USA
    Dev Psychopathol 16:1029-46. 2004
    ....
  43. ncbi Morphometric brain abnormalities in boys with conduct disorder
    Thomas Huebner
    Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital, RWTH Aachen, Germany
    J Am Acad Child Adolesc Psychiatry 47:540-7. 2008
    Children with the early-onset type of conduct disorder (CD) are at high risk for developing an antisocial personality disorder. Although there have been several neuroimaging studies on morphometric differences in adults with antisocial ..
  44. ncbi The role of callous and unemotional traits in the diagnosis of conduct disorder
    Richard Rowe
    University of Sheffield, UK
    J Child Psychol Psychiatry 51:688-95. 2010
    ..We investigate this hypothesis in a large, nationally representative sample of 5-16-year-olds. We also examine the characteristics of children with high CU traits but without CD...
  45. pmc Investigating different factor structures of the psychopathy checklist: youth version: confirmatory factor analytic findings
    Shayne Jones
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Psychol Assess 18:33-48. 2006
    ..The decision to use the 3- or 4-factor model will likely hinge on researchers' underlying conceptualization of psychopathy, specifically whether antisocial behavior is viewed as a core feature of this construct...
  46. ncbi Reduced eye gaze explains "fear blindness" in childhood psychopathic traits
    Mark R Dadds
    School of Psychology, University of New South Wales, Sydney, Australia
    J Am Acad Child Adolesc Psychiatry 47:455-63. 2008
    ..This study tested whether psychopathic traits are associated with reduced attention to the eye region of other people's faces...
  47. ncbi Callous-unemotional traits and subtypes of conduct disorder
    P J Frick
    Department of Psychology, University of New Orleans, Louisiana 70148, USA
    Clin Child Fam Psychol Rev 2:149-68. 1999
    ..Both approaches help designate children who many show different causal processes underlying their severe aggressive and antisocial behavior, and who may warrant different approaches to treatment...
  48. ncbi A model of differential amygdala activation in psychopathy
    Caroline Moul
    School of Psychology, University of New South Wales, Sydney, New South Wales, Australia
    Psychol Rev 119:789-806. 2012
    ..Supporting evidence concerning some of the neurochemicals implicated in psychopathy is then reviewed. Implications of the model and areas of future research are discussed...
  49. ncbi Inhibitory control and negative emotional processing in psychopathy and antisocial personality disorder
    Edelyn Verona
    Department of Psychology, University of Illinois at Urbana Champaign, Champaign, IL 61820, USA
    J Abnorm Psychol 121:498-510. 2012
    ..More work in particular is needed to clarify differential deficits in offenders with antisocial personality disorder (APD) who differ on psychopathic traits, as APD and psychopathy are considered separate, albeit ..
  50. ncbi Psychopathic traits and preattentive threat processing in children: a novel test of the fearlessness hypothesis
    Patrick D Sylvers
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195 6560, USA
    Psychol Sci 22:1280-7. 2011
    ..Future research should focus on preattentive processing of fear in individuals with callous-unemotional traits, and on the implications of preattentive-processing deficits for treatment and theory development...
  51. ncbi Long-term effects of nurse home visitation on children's criminal and antisocial behavior: 15-year follow-up of a randomized controlled trial
    D Olds
    University of Colorado Health Sciences Center, Denver 80218, USA
    JAMA 280:1238-44. 1998
    ..However, the long-term effects of this program on children's antisocial behavior have not been examined...
  52. ncbi Significance of childhood conduct problems to later development of conduct disorder among children with ADHD: a prospective follow-up study
    Salvatore Mannuzza
    New York University Child Study Center, NYU School of Medicine, New York, New York 10016, USA
    J Abnorm Child Psychol 32:565-73. 2004
    ..The same relationships were found between childhood ODD and CD behaviors, and antisocial personality disorder in adulthood (mean age, 25)...
  53. ncbi Very early predictors of conduct problems and crime: results from a national cohort study
    Joseph Murray
    Institute of Criminology, University of Cambridge, Sidgwick Avenue, England
    J Child Psychol Psychiatry 51:1198-207. 2010
    ..Longitudinal research has produced a wealth of knowledge about individual, family, and social predictors of crime. However, nearly all studies have started after children are age 5, and little is known about earlier risk factors...
  54. ncbi Theory of mind and psychopathy: can psychopathic individuals read the 'language of the eyes'?
    R A Richell
    Institute of Cognitive Neuroscience, Department of Psychology, University College, London, UK
    Neuropsychologia 41:523-6. 2003
    ..Results indicated that the psychopathic individuals did not present with any generalised impairment in ToM. The data are discussed with reference to the putative neural system mediating performance on this task and models of psychopathy...
  55. ncbi Limbic abnormalities in affective processing by criminal psychopaths as revealed by functional magnetic resonance imaging
    K A Kiehl
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    Biol Psychiatry 50:677-84. 2001
    ..CONCLUSIONS: These data suggest that the affective abnormalities so often observed in psychopathic offenders may be linked to deficient or weakened input from limbic structures...
  56. ncbi Neural correlates of social cooperation and non-cooperation as a function of psychopathy
    James K Rilling
    Department of Anthropology, Emory University, Atlanta, Georgia 30322, USA
    Biol Psychiatry 61:1260-71. 2007
    ..In this study, we probed the behavioral, emotional, and neural correlates of psychopathic traits within the context of a dyadic social interaction...
  57. ncbi Callous-unemotional traits in a community sample of adolescents
    Cecilia A Essau
    Roehampton University, London, UK
    Assessment 13:454-69. 2006
    ..Furthermore, the traits showed predicted associations with sensation seeking and the Big Five personality dimensions, supporting the construct validity of the measure of CU traits...
  58. pmc Longitudinal evidence that psychopathy scores in early adolescence predict adult psychopathy
    Donald R Lynam
    Department of Psychological Sciences, Purdue University, West Lafayette, IN 47907 2081, USA
    J Abnorm Psychol 116:155-65. 2007
    ..Implications and future directions are discussed...
  59. ncbi Psychopathic, not psychopath: taxometric evidence for the dimensional structure of psychopathy
    John F Edens
    Department of Psychology, Southern Methodist University, Dallas, TX 75275, USA
    J Abnorm Psychol 115:131-44. 2006
    ..The authors discuss the theoretical, public policy, and practice-level implications of these findings...
  60. ncbi Impaired social response reversal. A case of 'acquired sociopathy'
    R J Blair
    Institute of Cognitive Neuroscience and Department of Psychology, University College London, UK
    Brain 123:1122-41. 2000
    ..Moreover, it is proposed that the orbitofrontal cortex may be implicated specifically either in the generation of these expectations or the use of these expectations to suppress inappropriate behaviour...
  61. pmc Lifetime criminality among boys with attention deficit hyperactivity disorder: a prospective follow-up study into adulthood using official arrest records
    Salvatore Mannuzza
    New York University Child Study Center, Department of Child and Adolescent Psychiatry, NYU School of Medicine, New York, NY 10016, USA
    Psychiatry Res 160:237-46. 2008
    ....
  62. ncbi The development of psychopathy
    R J R Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Heath, Department of Health and Human Services, Bethesda, MD, USA
    J Child Psychol Psychiatry 47:262-76. 2006
    ..These impairments disrupt the impact of standard socialization techniques and increase the risk for frustration-induced reactive aggression respectively...
  63. ncbi Callous-unemotional traits and conduct problems in the prediction of conduct problem severity, aggression, and self-report of delinquency
    Paul J Frick
    Department of Psychology, University of New Orleans, New Orleans, Louisiana 70148, USA
    J Abnorm Child Psychol 31:457-70. 2003
    ....
  64. ncbi Facial emotion processing in criminal psychopathy. Preliminary functional magnetic resonance imaging study
    Quinton Deeley
    Section of Brain Maturation, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 189:533-9. 2006
    ..It has been suggested that people with psychopathic disorders lack empathy because they have deficits in processing distress cues (e.g. fearful facial expressions)...
  65. ncbi Cortex and amygdala morphology in psychopathy
    Marina Boccardi
    LENITEM Laboratory of Epidemiology, Neuroimaging, and Telemedicine IRCCS San Giovanni di Dio FBF, Via Pilastroni, 4, 25100, Brescia, Italy
    Psychiatry Res 193:85-92. 2011
    ....
  66. ncbi What happens to "bad" girls? A review of the adult outcomes of antisocial adolescent girls
    K A Pajer
    Department of Psychiatry, Allegheny University of the Health Sciences, Pittsburgh, PA 15212, USA
    Am J Psychiatry 155:862-70. 1998
    ..The purpose of this article is to review critically the data on the adult outcomes of adolescent girls with antisocial behavior...
  67. ncbi The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence
    Sheng Yu Lee
    Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Alcohol Clin Exp Res 33:1589-95. 2009
    ..of this 5HT1B gene variant between anxiety-depression alcoholism (ANX/DEP ALC) and antisocial alcoholism (antisocial ALC) subgroups because of the high comorbidity of anxiety-depression, antisocial personality disorder, and AD.
  68. ncbi Exploring epistasis in candidate genes for antisocial personality disorder
    Jorge Mauricio Cuartas Arias
    Department of Psychiatry, Faculty of Medicine, Universidad de Antioquia, Medellin, Colombia
    Psychiatr Genet 21:115-24. 2011
    To identify and characterize high-order gene-to-gene interactions in antisocial personality disorder (ASPD).
  69. ncbi Salivary cortisol and aggression in a population-based longitudinal study of adolescent males
    I van Bokhoven
    Department of Child and Adolescent Psychiatry, UMCU, Utrecht, The Netherlands
    J Neural Transm 112:1083-96. 2005
    ..Adolescent boys with chronic reactive aggression and those who scored high on aggressive CD symptoms seem to have a more active hypothalamic-pituitary-adrenal system...
  70. pmc Specifying the attentional selection that moderates the fearlessness of psychopathic offenders
    Arielle R Baskin-Sommers
    Department of Psychology, University of Wisconsin, 1202 W Johnson St, Madison, WI 53706, USA
    Psychol Sci 22:226-34. 2011
    ..The results not only provide new evidence that attention moderates the fearlessness of psychopathic individuals, but also implicate an early attention bottleneck as a proximal mechanism for deficient response modulation in psychopathy...
  71. pmc Feeling, caring, knowing: different types of empathy deficit in boys with psychopathic tendencies and autism spectrum disorder
    Alice P Jones
    Department of Psychology, Goldsmiths College, University of London, Lewisham Way, London, UK
    J Child Psychol Psychiatry 51:1188-97. 2010
    ....
  72. ncbi Identifying psychopathy subtypes on the basis of personality structure
    Brian M Hicks
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Psychol Assess 16:276-88. 2004
    ..These results suggest that psychopaths as defined by the PCL-R includes distinct subtypes, distinguishable in terms of personality structure, that may reflect different etiologies...
  73. ncbi Effects of induced anger in patients with antisocial personality disorder
    J Lobbestael
    Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands
    Psychol Med 39:557-68. 2009
    Anger is the main deregulated emotion in patients with antisocial personality disorder (ASPD)...
  74. ncbi Response to emotional stimuli in boys with conduct disorder
    Sabine C Herpertz
    Department of Psychiatry and Psychotherapy, Rostock University, Gehlsheimer Str 20, D 18147 Rostock, Germany
    Am J Psychiatry 162:1100-7. 2005
    ..In the search for biological risk factors that predispose children to the development of antisocial personality disorder, research has provided substantial data suggesting that autonomic hyporesponsiveness indicates a ..
  75. pmc An item response theory analysis of DSM-IV conduct disorder
    Heather Gelhorn
    School of Medicine at the University of Colorado, Denver, CO, USA
    J Am Acad Child Adolesc Psychiatry 48:42-50. 2009
    ....
  76. pmc The other allele: exploring the long allele of the serotonin transporter gene as a potential risk factor for psychopathy: a review of the parallels in findings
    Andrea L Glenn
    Department of Psychology, University of Pennsylvania, 3720 Walnut Street, Philadelphia, PA 19104, USA
    Neurosci Biobehav Rev 35:612-20. 2011
    ..It is suggested that the long/long genotype may be a potential risk factor for the development of psychopathic traits...
  77. pmc Psychopathic personality traits: heritability and genetic overlap with internalizing and externalizing psychopathology
    Daniel M Blonigen
    Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455 0344, USA
    Psychol Med 35:637-48. 2005
    ..The current study was designed to fill these gaps in the literature...
  78. ncbi Adolescent psychopathy and personality theory--the interpersonal circumplex: expanding evidence of a nomological net
    Randall T Salekin
    Department of Psychology, The University of Alabama, Tuscaloosa, Alabama 35487, USA
    J Abnorm Child Psychol 33:445-60. 2005
    ..The implications of the current study are discussed...
  79. ncbi MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder
    Sheng Yu Lee
    The Institute of Behavioral Medicine, Graduate Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, No 138 Sheng Li Road, Tainan, Taiwan, Republic of China
    Alcohol Clin Exp Res 33:985-90. 2009
    ..The objective of this study is to determine whether the interaction between the MAOA and the ALDH2 genes is associated with subjects with antisocial personality disorder (ASPD) having alcoholism.
  80. ncbi The association between DRD2/ANKK1, 5-HTTLPR gene, and specific personality trait on antisocial alcoholism among Han Chinese in Taiwan
    Chin Yeh Wu
    Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Republic of China
    Am J Med Genet B Neuropsychiatr Genet 147:447-53. 2008
    ..Most previous studies have failed to recruit subjects that have antisocial personality disorder without alcoholism due to the high coexisting likelihood of having antisocial personality disorder ..
  81. ncbi Disentangling the underlying dimensions of psychopathy and conduct problems in childhood: a community study
    Mark R Dadds
    School of Psychology, University of New South Wales, Sydney, NSW, Australia
    J Consult Clin Psychol 73:400-10. 2005
    ..These results indicate that although the dimensions of the APSD overlap with dimensions of the disruptive behavior disorders, CU traits have unique predictive validity in childhood...
  82. ncbi Psychopathic features in a juvenile diversion population: reliability and predictive validity of two self-report measures
    Diana M Falkenbach
    Department of Mental Health Law and Policy, University of South Florida, Tampa, FL 33612, USA
    Behav Sci Law 21:787-805. 2003
    ..56). Although further research is needed prior to the clinical use of these measures, these results signal the potential of such measures to inform clinical judgments regarding treatment compliance and risk with justice-involved youth...
  83. ncbi P3 event-related potential impairments in antisocial and psychopathic individuals: a meta-analysis
    Yu Gao
    Department of Criminology, University of Pennsylvania, Philadelphia, PA 19104 6286, USA
    Biol Psychol 82:199-210. 2009
    ..e., aggression, antisocial personality disorder, conduct disorder/oppositional-defiant disorder, and psychopathy), whereas this association in ..
  84. ncbi Modeling growth in boys' aggressive behavior across elementary school: links to later criminal involvement, conduct disorder, and antisocial personality disorder
    Cindy M Schaeffer
    Department of Psychology, University of Maryland Baltimore County, Baltimore, MD 21250, USA
    Dev Psychol 39:1020-35. 2003
    ..increasing trajectories were at increased risk for conduct disorder, juvenile and adult arrest, and antisocial personality disorder. Concentration problems were highest among boys with a chronic high trajectory and also ..
  85. ncbi Assessing violence risk and psychopathy in juvenile and adult offenders: a survey of clinical practices
    Jodi L Viljoen
    Simon Fraser University, Burnaby, British Columbia, Canada
    Assessment 17:377-95. 2010
    ..Juvenile risk reports were more likely than adult reports to routinely discuss treatment and protective factors, and provide recommendations to reevaluate risk. The implications of these findings are discussed...
  86. ncbi Antisocial personality disorder and cocaine dependence: their effects on behavioral and electroencephalographic measures of time estimation
    L O Bauer
    Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
    Drug Alcohol Depend 63:87-95. 2001
    ..one of two subgroups based upon the presence (n=20) versus absence (n=37) of a comorbid diagnosis of Antisocial Personality Disorder (APD)...
  87. ncbi Adolescents with psychopathic characteristics in a substance abusing cohort: treatment process and outcomes
    Melanie L O'Neill
    Institute for Addictive Disorders, Department of Psychiatry, Drexel University College of Medicine, Department of Psychology, Drexel University, Philadelphia, Pennsylvania, USA
    Law Hum Behav 27:299-313. 2003
    ..Implications for treatment and future research with adolescents displaying psychopathic characteristics are discussed...
  88. ncbi Negative association between plasma cortisol levels and aggression in a high-risk community sample of adolescents
    Luise Poustka
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    J Neural Transm 117:621-7. 2010
    ..This result suggests that the association between cortisol levels and aggression in adolescents is mediated rather by impulsivity than by unemotional or psychopathic traits...
  89. ncbi Lifetime comorbidity of antisocial personality disorder and anxiety disorders among adults in the community
    Renee D Goodwin
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Psychiatry Res 117:159-66. 2003
    The association between lifetime anxiety disorders, conduct disorder (CD), and antisocial personality disorder (ASPD) among adults in the community was explored...
  90. ncbi Verbal ability and delinquency: testing the moderating role of psychopathic traits
    Luna C Munoz
    Orebro University, Orebro, Sweden
    J Child Psychol Psychiatry 49:414-21. 2008
    ..Thus, the aim of the current study was to examine whether psychopathy moderates the relationship between verbal abilities and delinquent behavior in a sample of detained youth...
  91. ncbi A large-scale meta-analysis relating the hare measures of psychopathy to antisocial conduct
    Anne Marie R Leistico
    The University of Alabama, 348 Gordon Palmer Hall, Box 870348, Tuscaloosa, AL 35487 0348, USA
    Law Hum Behav 32:28-45. 2008
    ..We provide potential explanations for the significant findings and discuss implications of the results for future research...
  92. ncbi Adolescent psychopathy and the big five: results from two samples
    Donald R Lynam
    Department of Psychology, University of Kentucky, Lexington, Kentucky 40506 0044, USA
    J Abnorm Child Psychol 33:431-43. 2005
    ....
  93. ncbi Psychopathic traits and conduct problems in community and clinic-referred samples of children: further development of the psychopathy screening device
    P J Frick
    Department of Psychology, University of New Orleans, 2001 Geology and Psychology Building, New Orleans, Louisiana 70148, USA
    Psychol Assess 12:382-93. 2000
    ..However, the callous and unemotional traits were only weakly associated with these symptoms after controlling for the other dimensions of psychopathy...
  94. ncbi The treatment of conduct problems in children with callous-unemotional traits
    David J Hawes
    School of Psychology, University of New South Wales, Sydney, Australia
    J Consult Clin Psychol 73:737-41. 2005
    ..These findings present important implications for the role of child temperament in intervention for conduct problems...
  95. ncbi Heterosexual risk behaviors in at-risk young men from early adolescence to young adulthood: prevalence, prediction, and association with STD contraction
    Deborah M Capaldi
    Oregon Social Learning Center, Eugene 97401, USA
    Dev Psychol 38:394-406. 2002
    ..Lower condom use also predicted STD contraction...
  96. ncbi Predictive validity of the Psychopathy Checklist: Youth Version for general and violent recidivism
    Raymond R Corrado
    School of Criminology, Simon Fraser University, Burnaby, BC
    Behav Sci Law 22:5-22. 2004
    ..Implications for the use of psychopathy assessments for risk during adolescence are discussed...
  97. ncbi Physiologically-indexed and self-perceived affective empathy in Conduct-Disordered children high and low on Callous-Unemotional traits
    Xenia Anastassiou-Hadjicharalambous
    Department of Psychology, University of Strathclyde, Glasgow, Scotland, UK
    Child Psychiatry Hum Dev 39:503-17. 2008
    ..Both CD groups reported fewer vicarious responses and scored lower than controls on the empathy index. These results support distinct deficits across CD subsets, suggestive of distinct mechanisms underlying their antisocial conduct...
  98. ncbi Emotional processing in children with conduct problems and callous/unemotional traits
    M Woodworth
    UBC Okanagan, Unit of Psychology and Computer Science, 3333 University Way, Kelowna, BC, Canada
    Child Care Health Dev 34:234-44. 2008
    ..The current study investigated the ability of children with disruptive behaviour disorders to label emotional faces and stories...
  99. ncbi Assessing the affective features of psychopathy in adolescence: a further validation of the inventory of callous and unemotional traits
    Annelore Roose
    Research Foundation, Flanders, Belgium
    Assessment 17:44-57. 2010
    ..The three ICU subscales showed distinctive patterns of associations with key external criteria. Implications and directions for future research are discussed...
  100. ncbi Predictors and outcomes of joint trajectories of callous-unemotional traits and conduct problems in childhood
    Nathalie M G Fontaine
    Department of Criminal Justice, Indiana University, 302 Sycamore Hall, Bloomington, IN 47405, USA
    J Abnorm Psychol 120:730-42. 2011
    ..Children with high CU traits and concomitant high levels of CP in childhood should be prioritized for targeted intervention...
  101. ncbi ERPs on a continuous performance task and self-reported psychopathic traits: P3 and CNV augmentation are associated with Fearless Dominance
    Scott R Carlson
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Biol Psychol 85:318-30. 2010
    ..More negative CNV and faster reaction time were also specifically related to Fearless Dominance. These results illustrate the need to examine the differential relationships between psychopathic traits and P3 amplitude...

Research Grants63

  1. Intimate partner violence in newly married couples: The role of illicit drug use.
    Philip H Smith; Fiscal Year: 2012
    ..Multi Level Modeling will be used to test for a longitudinal relation between IDU and IPV, as well as mediation and moderation effects. ..
  2. X-linked Genes, Histone Modifications, and Behavior
    Jun Xu; Fiscal Year: 2013
    ..In mice, aggression is influenced by both steroid hormones and sex chromosomes. We propose to test the possible connection between aggression and an X-linked gene whose mutations in human cause the clinical feature of aggression. ..
  3. Emergence of Adolescent Substance Use Problems from the Externalizing Spectrum
    KEVIN MICHAEL KING; Fiscal Year: 2010
    ..problems that occur across the lifespan (ADHD, oppositional defiant disorder, conduct disorder, and antisocial personality disorder)...
  4. Precursors to Borderline and Antisocial Personality Disorders in Adolescence
    Lori N Scott; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Borderline Personality Disorder (BPD) and Antisocial Personality Disorder (ASPD) are among the most serious, complex, and costly public health concerns facing the US healthcare and criminal justice ..
  5. CA3-Restricted BDNF Knockout as a Model of Abnormal Traits in Social Behaviors
    Alexei Morozov; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Antisocial personality disorder (ASPD) is "...a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood...
  6. NEUROPHYSIOLOGY IN CHILDREN AT HIGH RISK FOR ALCOHOLISM
    Bernice Porjesz; Fiscal Year: 2010
    ..Retesting will begin in the last year of this application, and will continuein the future The identification of individuals with neuroelectric deficits will have great utility in prevention initiatives ..
  7. Psychometric and Neurobiological Mechanisms of Impulse Control Disorders
    Lindsay Nelson; Fiscal Year: 2010
    ..impulse-control-including child conduct disorder and attention- deficit/hyperactivity disorder, adult antisocial personality disorder, and alcohol/drug dependence (collectively known as externalizing disorders)-are debilitating for ..
  8. Development of Externalizing Behavior Problems: Gene-Environment Interplay
    Laura A Baker; Fiscal Year: 2013
    ..aggressive behavior and their risk factors during a period of greatest risk for criminal offending, antisocial personality disorder and substance abuse...
  9. A Longitudinal Study of Alcohol Dependence in Late Adolescence
    Tim Bogg; Fiscal Year: 2010
    ....
  10. Long-Term Abstinence Clinical Issues and CNS Disinhibition
    George Fein; Fiscal Year: 2012
    ..individuals with lifetime or current psychiatric diagnoses were excluded, 7) that current symptoms of Antisocial Personality Disorder were minimal despite evidence of deviance proneness, impulsivity and poor decision- making, and 8) ..
  11. A Longitudinal Study of Alcohol Dependence in Late Adolescence
    Tim Bogg; Fiscal Year: 2013
    ..abstract_text> ..
  12. Behavioral Genetics of Impulsivity
    Lynn Fairbanks; Fiscal Year: 2005
    ..problems, including conduct disorder, attention deficit hyperactivity disorder, substance abuse, antisocial personality disorder, criminality and violence...
  13. Neuro-Cognitive Aspects of Opiate Abuse & Antisocial Behavior
    Jasmin Vassileva; Fiscal Year: 2004
    ..Further, co-morbid conditions, such as Antisocial Personality Disorder (APD) and psychopathy, additionally complicate the clinical picture and daily function of heroin-..
  14. Alcoholism and Suicide
    KENNETH CONNER; Fiscal Year: 2002
    ..In Aim 1, two predisposing factors, major depression and antisocial personality disorder (ASP), will be investigated as potential moderators (effect modifiers) of the association between ..
  15. Risks for Transitions in Drug use Among Urban Adults
    William W Eaton; Fiscal Year: 2011
    ..psychiatric and behavioral disorders, such as depression, alcohol disorders, antisocial behaviors and antisocial personality disorder. Important social environmental influences include engagement in adult roles, development of ..
  16. ISRAELI REACTIONS TO MISSILE ATTACKS DURING THE GULF WAR
    Itzhak Levav; Fiscal Year: 1991
    ....
  17. HIV RISK BEHAVIOR AND VIOLENCE AMONG CRACK USERS
    Tk Logan; Fiscal Year: 2002
    ..violent victimization, and HIV risk behavior among crack users; (2) To examine the association of antisocial personality disorder, impulsivity, anxiety, depression, anger, hostility, serotonin, and testosterone with violence and ..
  18. Inhibitory Control: Toward a Vulnerability Phenotype
    FRANCES GABBAY; Fiscal Year: 2007
    ..Disinhibitory psychopathologies, including attention-deficit hyperactivity and antisocial personality disorder, have a high comorbidity with drug and alcohol abuse...
  19. PHARMACOLOGICAL TREATMENT OF ALCOHOLIC SUBTYPES
    Barbara Powell; Fiscal Year: 1991
    ....
  20. Does psycholigocal wellness predict treatment response?
    Arthur Alterman; Fiscal Year: 2006
    ..abstract_text> ..
  21. ALTERING BEHAVIORAL RISK FOR DRUG DEPENDENCE
    DON CHEREK; Fiscal Year: 2001
    ..populations of subjects: (1) subjects with a history of childhood conduct disorder (CD) + current antisocial personality disorder (ASPD), probably the highest risk population and (2) matched controls the drug to be employed are: ..
  22. Oxytocin Receptors in Human and Non-human Primates
    Maria Boccia; Fiscal Year: 2006
    ..such as autism, or psychopathological syndromes with social and affective components, such as antisocial personality disorder or schizophrenia...
  23. Reward, Impulsivity and Cocaine Addiction; fMRI Studies
    Godfrey Pearlson; Fiscal Year: 2009
    ..Overall, we thus plan to elucidate the inter-relationship between two important substance abuse-related factors at both a behavioral and a neural circuit level. ..
  24. NEUROGENETICS, SEROTONIN, AND HUMAN AGGRESSION
    STEPHEN MANUCK; Fiscal Year: 2003
    Aggression is a prominent feature of many clinical conditions (such as antisocial personality disorder), a common cause of criminal incarceration, and a frequent concomitant of alcohol and other substance abuse...
  25. MONOAMINE PREDICTORS OF DRUG ABUSE/SOCIOPATHY
    Roy King; Fiscal Year: 1992
    ..In addition, psychopharmacological interventions that raise levels of PAA, such as the MAO-B inhibitors, may potentially help compensate for this dysfunctional impulsivity...
  26. PREDICTING SEXUAL/ANTISOCIAL BEHAVIOR AGAINST WOMEN
    Neil Malamuth; Fiscal Year: 1991
    ..We will also control for the tendency to report only socially desirable behavior and general personality pathology. The study will be the first to test, within a longitudinal context, the predictive validity of the model outlined...
  27. PSYCHIATRIC GENETIC EPIDEMIOLOGY
    Kenneth Kendler; Fiscal Year: 2000
    ..of psychiatric disorders, including affective disorder, schizophrenia, anxiety disorders, bulimia, antisocial personality disorder, and substance abuse disorders...
  28. GENETIC LINKAGE STUDY OF ALCOHOLISM
    Raymond Crowe; Fiscal Year: 1993
    ..of one additional relative with either alcoholism or alcoholism-related disorders (depression or antisocial personality disorder, i.e., depression spectrum disease)...
  29. PRECURSORS TO ANTISOCIAL PERSONALITY AND VIOLENCE
    Rolf Loeber; Fiscal Year: 2004
    ..The latest assessments were at ages 18 and 19, with the aim of documenting antisocial personality disorder and the infliction of harm...
  30. COURSE OF DRUG USE DISORDERS--EFFECTS OF COMORBIDITY
    Deborah Hasin; Fiscal Year: 1999
    ..The effects of concurrent comorbid mental disorders (particularly alcoholism, major depression and antisocial personality disorder) have been previously studied, but many questions remain unanswered...
  31. ANTISOCIAL PERSONALITY AND ALCOHOL INDUCED AGGRESSION
    FREDERICK MOELLER; Fiscal Year: 1999
    ..Specific Aims: 1. To measure alcohol induced aggressive responding in subjects with Antisocial Personality Disorder (ASP and matched controls 2...
  32. DIAGNOSTIC AND COGNITIVE VULNERABILITIES TO RELAPSE
    Collins Lewis; Fiscal Year: 1992
    ..Information from this study will add to the knowledge of the relapse process, and give therapists more information about who is most vulnerable to early relapse and about what their vulnerabilities are...
  33. INTERPERSONAL SKILLS OF ADULT CHILDREN OF ALCOHOLICS
    MARILYN SENCHAK; Fiscal Year: 1992
    ..Family factors are expected to mediate/moderate the relation between paternal drinking and interpersonal skills acquisition among children of alcoholics...
  34. SOCIOPATHY AND TREATMENT OUTCOME IN ALCOHOLIC PATIENTS
    CHARLES O BRIEN; Fiscal Year: 1993
    ..Two other studies will examine important psychometric properties of the SCID antisocial personality disorder (ASP) diagnosis (using RDC and DSM-IIIR criteria) and the Psychopathy Checklist (PCL) developed by ..
  35. Personality Features in Social Deviancy
    Norman Poythress; Fiscal Year: 2004
    ..two major objectives: (1) to explore the use of the construct of psychopathy in the diagnosis of antisocial personality disorder (APD), and (2) to evaluate the reliability and validity of two recently developed self-report ..
  36. Psychological Wellness and Alcoholism Treatment Outcome
    Arthur Alterman; Fiscal Year: 2005
    ..abstract_text> ..
  37. FUNCTIONAL NEUROANATOMY OF ADHD--A TRAINING PROJECT
    Julie Schweitzer; Fiscal Year: 2001
    ..the symptoms are more likely to experience occupational difficulties, abuse drugs, develop an antisocial personality disorder, and function less successfully in society...
  38. The Genetics of Smoking; The Transtheoretical Model
    Qiang Fu; Fiscal Year: 2009
    ..and genetic influences on depression and anxiety disorders;3) determining how genetic influences on antisocial personality disorder (or conduct disorder) versus genetic influences on depression and anxiety disorders, contribute to ..
  39. PATHWAYS TO ADULT PSYCHOPATHOLOGY: ETIOLOGICAL FACTORS
    Judy Silberg; Fiscal Year: 2001
    ..pathways to Major Depression, Generalized Anxiety disorders, social, Situational, and Simple Phobias, Antisocial Personality Disorder, Alcoholism, Drug use, and Eating Disorder...
  40. SUBSTANCE USE: FAMILY, FRIEND, AND COMMUNITY FACTORS
    Claire Sterk; Fiscal Year: 2004
    ..between cocaine dependence and comorbid psychopathology, particularly depression, anxiety, antisocial personality disorder, and post-traumatic stress syndrome; (3) to examine the role of specific community factors in the ..
  41. ANXIETY, DISINHIBITION, AND RISK FOR DRUG ABUSE
    Kimberly Yonkers; Fiscal Year: 2003
    ..1) substance abuse only, 2) substance abuse and comorbid anxiety disorder, 3) substance abuse and antisocial personality disorder, and 3) no psychiatric disorders: 1...
  42. INTERGENERATIONAL TRANSMISSION--SUBSTANCE ABUSE
    HOWARD MOSS; Fiscal Year: 2001
    ..to elucidate the etiology, course, and sequelae of conditions such as SUD, Conduct Disorder (CD), and Antisocial Personality Disorder (ASPD) through the integration of knowledge from multiple disciplines such as psychology, psychiatry, ..
  43. COCAINE CRAVING AND COPING IN TREATMENT AND RELAPSE
    Damaris Rohsenow; Fiscal Year: 2000
    ..Results will be used to add to theoretical understandings of cocaine abuse and relapse, and may provide information useful for developing future treatment programs. ..
  44. VIOLENCE--INTEGRATING SOCIAL AND PHYSIOLOGICAL FACTORS
    Adrian Raine; Fiscal Year: 2003
    ....
  45. Alcoholism risk and protective factors in Trinidad
    Cindy Ehlers; Fiscal Year: 2006
    ..Study findings can be compared to similar studies being conducted in the US. We believe these studies will allow for the identification of risk and protective factors for alcoholism in these islands. [unreadable] [unreadable]..
  46. ADOLESCENT MARIJUANA USE IN NATIVE AMERICANS
    Cindy Ehlers; Fiscal Year: 2008
    ..abstract_text> ..
  47. Neurobehavioral Consequences of Adolescent Alcohol
    Cindy Ehlers; Fiscal Year: 2008
    ..AIM 3: To investigate the neurochemical substrates underlying the lasting neurobehavioral consequences of adolescent ethanol exposure, with a focus on NMDA systems ..
  48. RISK FACTORS FOR ALCOHOLISM IN NATIVE AMERICANS
    Cindy Ehlers; Fiscal Year: 2006
    ..The identification of such variables may potentially be useful in the development of specific prevention and treatment programs for this population as well as other Native American tribes. ..
  49. ADULT ANTISOCIAL OUTCOMES OF PSYCHOPATHIC CHILDREN
    Donald Lynam; Fiscal Year: 2003
    ..Three separable, but related, outcomes are assessed-- psychopathy (in Cleckley's sense), antisocial personality disorder, and offending...
  50. Contextual Influences in Prisoner Research
    JOHN EDENS; Fiscal Year: 2010
    ..These data will be the first of their kind and will inform policy makers and IRB boards about offender groups'views of potential threats to voluntary research participation in these settings. ..
  51. Genetic Influence on Personality Disorder
    Jeanette Taylor; Fiscal Year: 2004
    ..abstract_text> ..
  52. INTERGENERATIONAL TRANSMISSION OF RISK
    DEBORAH CAPALDI; Fiscal Year: 2002
    ..Using this design, we will be able to examine the intergenerational transmission of parenting styles, as well as direct child effects and interactions between parenting and child effects. ..
  53. LIFE COURSE ANTISOCIAL BEHAVIOR IN MALES
    DEBORAH CAPALDI; Fiscal Year: 2007
    ..g., antisocial behavior in childhood), and similar contextual, social relationships, and behavioral factors in adulthood can explain changes in the course of behaviors across the early adult period. [unreadable] [unreadable]..
  54. Norepinephrine and Impulsivity
    Alan Swann; Fiscal Year: 2009
    ..potentials (sensory gating) in euthymic and manic subjects with bipolar disorder, subjects with antisocial personality disorder, and healthy control subjects, 2) to investigate effects of pharmacologically decreasing ..
  55. RISK FOR DYSFUNCTIONAL RELATIONSHIPS FOR YOUNG ADULTS
    DEBORAH CAPALDI; Fiscal Year: 2002
    ....
  56. PREVENTION OF CIGARETTE SMOKING IN ADHD YOUTH
    Joseph Biederman; Fiscal Year: 2001
    ..Since there are estimated to be 3.5 million children with ADHD and 20% have been shown to be smokers, targeting this group could potentially impact 700,000 children and adolescents. ..
  57. A Family-Genetic Study of Pathological Gambling
    Donald Black; Fiscal Year: 2009
    ..three distinct subtypes of PG), and to verify whether the aggregation of PG, substance misuse, and antisocial personality disorder comprise an "externalizing factor" as hypothesized by Krueger...
  58. Cognitive Behavioral Treatment of PTSD in SMI Clients
    Kim T Mueser; Fiscal Year: 2010
    ..The results of this research will bring the field one step closer to having an evidence-based practice for trauma and PTSD in clients with SMI. ..
  59. Course of psychopathology in female youth: Analysis with extant longitudinal data
    Joseph Biederman; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  60. Adult Outcome of Attention Deficit Hyperactivity Disorder
    Joseph Biederman; Fiscal Year: 2007
    ..For these reasons, we expect the proposed work to clarify the course and outcome of ADHD. ..
  61. Bupropion VS Placebo to Treat Pathological Gambling
    Donald Black; Fiscal Year: 2004
    ..abstract_text> ..
  62. Collaborative Pediatric Bipolar Disorder Conference
    Joseph Biederman; Fiscal Year: 2007
    ..While the proposed conference does not intend to solve all outstanding problems associated with pediatric bipolar disorder, it will provide a forum to begin formulating a solution. ..
  63. LONGITUDINAL FOLLOW UP OF ADHD GIRLS AND THEIR SIBLINGS
    Joseph Biederman; Fiscal Year: 2002
    ....