Genomes and Genes
Summary: The inability to generate oral-verbal expression, despite normal comprehension of speech. This may be associated with BRAIN DISEASES or MENTAL DISORDERS. Organic mutism may be associated with damage to the FRONTAL LOBE; BRAIN STEM; THALAMUS; and CEREBELLUM. Selective mutism is a psychological condition that usually affects children characterized by continuous refusal to speak in social situations by a child who is able and willing to speak to selected persons. Kussmal aphasia refers to mutism in psychosis. (From Fortschr Neurol Psychiatr 1994; 62(9):337-44)
Publications229 found, 100 shown here
- The development and psychometric properties of the selective mutism questionnaireR Lindsey Bergman
Department of Psychiatry and Biobehavioral Science, University of California, Los Angeles, USA
J Clin Child Adolesc Psychol 37:456-64. 2008Research on selective mutism (SM) has been limited by the absence of standardized, psychometrically sound assessment measures...
- Sertraline treatment of 5 children diagnosed with selective mutism: a single-case research trialJ S Carlson
Department of Psychology, University of Wisconsin Madison, USA
J Child Adolesc Psychopharmacol 9:293-306. 1999..study, we examined the efficacy and acceptability of sertraline treatment in children diagnosed with selective mutism. We utilized a double-blind, placebo-controlled trial of sertraline within a replicated multiple baseline/across ..
- Post-traumatic mutism in childrenXi Jian
Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, PR China
Brain Inj 23:445-9. 2009To explore the pathological mechanism of post-traumatic mutism (PTM) in children.
- Catatonic mutism after liver transplant rapidly reversed with lorazepamMargot M O'Donnell
Gen Hosp Psychiatry 29:280-1. 2007
- Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: a prospective study by the Children's Oncology GroupPatricia L Robertson
Department of Pediatrics, University of Michigan Health System, Ann Arbor, Michigan 48109 0203, USA
J Neurosurg 105:444-51. 2006Cerebellar mutism syndrome (CMS) is a unique postoperative syndrome typically arising 1 to 2 days after resection of a midline posterior fossa tumor; it consists of diminished speech progressing to mutism, emotional lability, hypotonia, ..
- A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traitsMurray B Stein
Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0855, USA
Biol Psychiatry 69:825-31. 2011Selective mutism (SM), considered an early-onset variant of social anxiety disorder, shares features of impaired social interaction and communication with autism spectrum disorders (ASDs) suggesting a possible shared pathophysiology...
- Selective mutism: are primary care physicians missing the silence?Richard H Schwartz
Department of Pediatrics, Inova Fairfax Hospital for Children, Falls Church, VA, USA
Clin Pediatr (Phila) 45:43-8. 2006To survey parents of children with selective mutism (SM) in regard to (1) the role of the primary care physician in the diagnosis of SM; (2) the social and school consequences of SM; and (3) their opinion of the effectiveness of different ..
- A brief review of selective mutism literatureValerie L Krysanski
Clinical Psychology, University of North Dakota, USA
J Psychol 137:29-40. 2003Selective mutism is a disorder characterized by a persistent failure to speak in certain social situations. It is typically diagnosed in childhood, and the disorder can last from just a few months to several years in some individuals...
- Anatomical correlates of early mutism in progressive nonfluent aphasiaM L Gorno-Tempini
UCSF Department of Neurology, Memory and Aging Center, 350 Parnassus Ave, Suite 800, Box 1207, San Francisco, CA 94143 1207, USA
Neurology 67:1849-51. 2006..In PNFA with early mutism, volume loss was more prominent in the pars opercularis and extended into the left basal ganglia...
- Mixed neuronal-glial tumor of the fourth ventricle and successful treatment of postoperative mutism with bromocriptine: case reportJun ichi Adachi
Department of Neurosurgery, Saitama Medical School, Saitama 350 0495, Japan
Surg Neurol 63:375-9. 2005..We describe the clinicopathologic features of a very rare rosette-forming glioneuronal tumor of the fourth ventricle and propose bromocriptine as a useful therapeutic agent for cerebellar mutism after posterior fossa surgery.
- Clozapine-resistant mutism in noncatatonic schizophreniaK K Basanth
J Postgrad Med 53:75-6. 2007
- The cerebellar mutism syndrome and its relation to cerebellar cognitive function and the cerebellar cognitive affective disorderElizabeth M Wells
Division of Neurology, Brain Tumor Institute, Children s National Medical Center, The George Washington University School of Medicine and Health Sciences, Washington DC 20010, USA
Dev Disabil Res Rev 14:221-8. 2008The postoperative cerebellar mutism syndrome (CMS), consisting of diminished speech output, hypotonia, ataxia, and emotional lability, occurs after surgery in up to 25% of patients with medulloblastoma and occasionally after removal of ..
- Postoperative motor speech production in children with the syndrome of 'cerebellar' mutism and subsequent dysarthria: a critical review of the literatureHyo Jung De Smet
Department of Linguistics, Vrije Universiteit Brussel, 808 Route de Lennik, B 1070 Brussels, Belgium
Eur J Paediatr Neurol 11:193-207. 2007Transient cerebellar mutism is a well-known clinical entity which may develop after surgery to the cerebellum...
- The pathophysiologic mechanism of cerebellar mutismBurak M Ozgur
Pediatric Neurosurgery, Children s Hospital of San Diego, San Diego, CA 92123, USA
Surg Neurol 66:18-25. 2006Cerebellar mutism (CM) is a postoperative complication of mainly pediatric posterior fossa surgery. Multiple theories exist for explaining this phenomenon...
- Postoperative mutism after removal of an anterior falcine meningiomaKadir Tahta
Department of Neurosurgery, Pamukkale University School of Medicine, Zeytinkoy mh Aksemsettin cd No 16, Denizli, Turkey
J Clin Neurosci 14:793-6. 2007Postoperative mutism is rare. We present a 65-year-old man who had transient mutism after resection of anterior falx meningioma...
- Cerebellar mutism in adults after posterior fossa surgery: a report of 2 casesJonathan H Sherman
Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
Surg Neurol 63:476-9. 2005b>Mutism has been associated with injury to midline cerebellar structures secondary to degenerative disease, tumors, hemorrhage, or surgery...
- Web-based CBT for selective mutismDaniel S S Fung
J Am Acad Child Adolesc Psychiatry 41:112-3. 2002
- Nonsurgical cerebellar mutism (anarthria) in two childrenLeena D Mewasingh
Department of Neurology, Children s University Hospital Queen Fabiola, Universite Libre de Bruxelles ULB, Belgium
Pediatr Neurol 28:59-63. 2003Cerebellar mutism (anarthria) is a well-described complication of posterior fossa tumor resection. It is accompanied by a characteristic behavior including irritability and autistic features...
- Reduced auditory efferent activity in childhood selective mutismYair Bar-Haim
Department of Psychology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Biol Psychiatry 55:1061-8. 2004Selective mutism is a psychiatric disorder of childhood characterized by consistent inability to speak in specific situations despite the ability to speak normally in others...
- Cerebellar mutism caused by arteriovenous malformation of the vermisA Al-Anazi
Department of Neurosurgery King Fahad Hospital of the University, Al Khobar, Saudi Arabia
Br J Neurosurg 15:47-50. 2001Transient mutism following posterior fossa tumour resection in children is well known in the literature. To our Knowledge, this phenomenon has never been reported without surgical intervention...
- Selective mutism: a review and integration of the last 15 yearsAndres G Viana
Department of Psychology, The Pennsylvania State University, University Park, PA 16802, USA
Clin Psychol Rev 29:57-67. 2009Selective mutism (SM) is a rare childhood disorder characterized by a lack of speech in one or more settings in which speaking is socially expected...
- Practitioner review: Psychosocial interventions for children with selective mutism: a critical evaluation of the literature from 1990-2005Sharon L Cohan
Department of Psychiatry, University of California San Diego, La Jolla, California, USA
J Child Psychol Psychiatry 47:1085-97. 2006There have been several reports of successful psychosocial interventions for children with selective mutism (SM), a disorder in which a child consistently fails to speak in one or more social settings (e.g...
- [Treatment of selective mutism]Siebke Melfsen
Klinik und Poliklinik für Kinder und Jugendpsychiatrie und Psychotherapie, Universitat Wurzburg
Z Kinder Jugendpsychiatr Psychother 35:399-407; quiz 408-9. 2007Selective mutism is a communication disorder of childhood in which the child does not speak in specific social situations despite the ability to speak in other situations...
- Selective mutism and social anxiety disorder: all in the family?Denise A Chavira
Department of Psychiatry, University of California, San Diego, USA
J Am Acad Child Adolesc Psychiatry 46:1464-72. 2007To examine the history of lifetime psychiatric disorders in the parents of children with selective mutism (SM) compared to parents of children in a control group.
- Moments in psychotherapyLenore C Terr
University of California, San Francisco, CA, USA
J Am Acad Child Adolesc Psychiatry 44:191-7. 2005
- Visual disturbance associated with postoperative cerebellar mutismStacie R Daniels
Department of Neurology, Walter Reed Army Medical Center, Washington, DC 20307, USA
Pediatr Neurol 32:127-30. 2005Cerebellar mutism is an uncommon complication of posterior fossa surgery. Manifestations include disturbances of articulation, prosody, and pitch, and, if severe, complete mutism...
- Neurologic complications associated with influenza A in children during the 2003-2004 influenza season in Houston, TexasStephen M Maricich
Section of Neurology, Department of Pediatrics, Texas Children s Hospital, Houston, Texas, USA
Pediatrics 114:e626-33. 2004....
- Cerebellar mutismMehmet Turgut
J Neurosurg Pediatr 1:262. 2008Cerebellar mutism syndrome (CMS) is a unique postoperative syndrome typically arising 1 to 2 days after resection of a midline posterior fossa tumor; it consists of diminished speech progressing to mutism, emotional lability, hypotonia, ..
- Suffering in silence: why a developmental psychopathology perspective on selective mutism is neededSharon L Cohan
Department of Psychology, San Diego State University, San Diego, CA, USA
J Dev Behav Pediatr 27:341-55. 2006..perspective is offered in an effort to organize the existing literature regarding the etiology of selective mutism (SM), a relatively rare disorder in which a child consistently fails to speak in 1 or more social settings (e.g...
- Prevalence and description of selective mutism in immigrant and native families: a controlled studyYoel Elizur
Psychology Department, The Hebrew University, Jerusalem, Israel
J Am Acad Child Adolesc Psychiatry 42:1451-9. 2003To assess the incidence of selective mutism (SM) in West Jerusalem's state preschools and evaluate social anxiety/phobia disposition (SAP), social competence (SC), markers of neurodevelopmental delay/disorder (NDD), mothers' psychological ..
- Characterizing selective mutism: is it more than social anxiety?Katharina Manassis
Department of Psychiatry, Hospital for Sick Children, Toronto, Ontario, Canada
Depress Anxiety 18:153-61. 2003Selective mutism (SM) occurs when a child persistently lacks speech in some social situations but not in others, despite the ability to use and comprehend language...
- Mutism after posterior fossa tumour resection in children: incomplete recovery on long-term follow-upPaul Steinbok
Division of Paediatric Neurosurgery, British Columbia s Children Hospital, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada
Pediatr Neurosurg 39:179-83. 2003b>Mutism after posterior fossa tumour resection is generally said to be transient. Our experience suggested that speech did not usually normalise, and that mutism was associated with neurologic deficits that did not recover fully.
- Differential diagnosis of selective mutism in bilingual childrenClaudio O Toppelberg
Judge Baker Children s Center, Children s Hospital Boston and Harvard Medical School Department of Psychiatry, Boston, MA 02120 3225, USA
J Am Acad Child Adolesc Psychiatry 44:592-5. 2005
- Treatment of selective mutism: focus on selective serotonin reuptake inhibitorsYaman Kaakeh
Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN, USA
Pharmacotherapy 28:214-24. 2008Abstract Selective mutism is a pediatric psychiatric disorder that occurs when a child consistently fails to speak in specific situations in which speaking is expected, such as at school and social gatherings, but speaks appropriately in ..
- Selective mutism. A school-based cross-sectional study from TurkeyI Karakaya
Department of Child and Adolescent Psychiatry, Kocaeli University Medical School, Derince Izmit, Kocaeli, Turkey
Eur Child Adolesc Psychiatry 17:114-7. 2008The aim of this study is to examine the prevalence of selective mutism (SM) in Kocaeli, Turkey.
- GJB2 mutations and additional disabilities in a pediatric cochlear implant populationS Wiley
Division of Developmental Disabilities, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH 45229, USA
Int J Pediatr Otorhinolaryngol 70:493-500. 2006..Studies on children with GJB2 mutations and cochlear implants have typically excluded children with additional disabilities...
- The pharmacological management of childhood anxiety disorders: a reviewShauna P Reinblatt
Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, The Johns Hopkins University School of Medicine, 600 N Wolfe St, CMSC 312, Baltimore, MD, USA
Psychopharmacology (Berl) 191:67-86. 2007..Psychopharmacological approaches to the treatment of pediatric anxiety have expanded over the past 20 years and increasing empirical evidence helps guide current clinical practice...
- [Severe cerebellar mutism after posterior fossa tumor resection]M Garcia Conde
Servicios de Neurocirugía, Unidad de Oncohematología Pediátrica, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
An Pediatr (Barc) 66:75-9. 2007Cerebellar mutism is an infrequent but important complication after posterior fossa surgery in children. Dysarthria, irritability and ataxia are among the signs and symptoms of this disorder, which are usually mild and self-limiting...
- Transient cerebellar mutism in childhoodMehmet Turgut
Childs Nerv Syst 23:477. 2007
- [Cerebellar mutism after removal of a vermian medulloblastoma in an adult]A Akhaddar
Service de Neurochirurgie, hôpital militaire d instruction Mohammed V, Hay Riyad, 10106 Rabat, Maroc
Neurochirurgie 54:548-50. 2008Cerebellar mutism is a rare postoperative phenomenon that generally occurs in children after resection of a cerebellar mass lesion...
- Long-term neuromotor speech deficits in survivors of childhood posterior fossa tumors: effects of tumor type, radiation, age at diagnosis, and survival yearsJoelene F Huber
Department of Pediatrics, University of Toronto, Ontario, Canada
J Child Neurol 22:848-54. 2007..Dysfluent and slow speech occur in cerebellar tumor survivors, regardless of tumor type and radiation history. Cerebellar tumors in childhood limit speech rate in adulthood...
- Social phobia, anxiety, oppositional behavior, social skills, and self-concept in children with specific selective mutism, generalized selective mutism, and community controlsCharles E Cunningham
Chedoke Campus, Hamilton Health Sciences, Hamilton, ON, Canada, L8N 3Z5
Eur Child Adolesc Psychiatry 15:245-55. 2006..anxiety, oppositional behavior, social skills, and self-concept in three groups: (1) 28 children with specific mutism (who did not speak to teachers but were more likely to speak to parents and peers at home and school); (2) 30 ..
- Parental responses to positive and negative emotions in anxious and nonanxious childrenJennifer L Hudson
J Clin Child Adolesc Psychol 37:303-13. 2008....
- The extent of social anxiety in combination with mental disordersSiebke Melfsen
Dept of Psychiatry for Children and Adolescents, University of Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany
Eur Child Adolesc Psychiatry 15:111-7. 2006..A total score above 20, which was assumed to indicate social anxiety, was observed in children with selective mutism (n = 9; M = 22.68; SD = 11.29) and in children with Asperger's Syndrome (n = 7; M = 20.77; SD = 13.77)...
- Transient cerebellar mutism caused by bilateral damage to the dentate nuclei after the second posterior fossa surgery. Case reportYoshikazu Kusano
Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan
J Neurosurg 104:329-31. 2006..A second operation was performed to remove the residue, after which the child suffered mutism. Three weeks post-surgery, he could only communicate through gestures...
- [Supplementary motor area syndrome with frontal glioma]Shigeki Watanabe
Department of Neurosurgery, Yamagata University School of Medicine, Japan
Brain Nerve 59:793-6. 2007..One dominant frontal glioma patient was followed by transient mutism and motor aphasia...
- Selective mutism: more than social anxiety?Robin Yeganeh
Maryland Center for Anxiety Disorders, University of Maryland College Park, USA
Depress Anxiety 23:117-23. 2006This study investigated the relationship between selective mutism (SM), social phobia (SP), oppositionality, and parenting styles...
- When silence is not golden: an integrated approach to selective mutismAlison McInnes
Department of Psychiatry Research, Hospital for Sick Children, Toronto, Ontario, Canada
Semin Speech Lang 26:201-10. 2005Selective mutism (SM) is a rare disorder that is associated with both anxiety and communication impairments...
- Examination of a social problem-solving intervention to treat selective mutismMark O'Reilly
Department of Speical Education, The University of Texas at Austin, Austin, TX 78712, USA
Behav Modif 32:182-95. 2008The authors examined the use of a social problem-solving intervention to treat selective mutism with 2 sisters in an elementary school setting...
- [Elective mutism--a disorder of social functioning or an emotional disorder?]Per Storgaard
Borne og Ungdomspsykiatrisk Hospital, Harald Selmers Vej 66, DK 8240 Risskov
Ugeskr Laeger 165:678-81. 2003Elective mutism is a relatively uncommon disorder characterized by consistent failure to speak in specific social settings, such as in school, despite speaking fluently in a variety of other situations...
- Cerebellar mutism associated with a midbrain cavernous malformation. Case report and review of the literatureMarjorie C Wang
Department of Neurosurgery, University of Colorado Health Sciences Center and The Children s Hospital, Denver 80262, USA
J Neurosurg 96:607-10. 2002The authors report a case of cerebellar mutism arising from a hemorrhagic midbrain cavernous malformation in a 14-year-old boy...
- Rapid resolution of social anxiety disorder, selective mutism, and separation anxiety with paroxetine in an 8-year-old girlRobert B Lehman
J Psychiatry Neurosci 27:124-5. 2002
- Bilateral crossed cerebello-cerebral diaschisis and mutism after surgery for cerebellar medulloblastomaT Sagiuchi
Department of Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
Ann Nucl Med 15:157-60. 2001A 7-year-old boy developed mutism after surgery for cerebellar medulloblastoma. Postoperative magnetic resonance imaging (MRI) showed atrophy of the cerebellar vermis and both cerebellar hemispheres, predominantly on the right side...
- Multiple informants' report of emotional and behavioural problems in a nation-wide sample of selective mute children and controlsH Kristensen
Nic Waal Institute of Child and Adolescent Psychiatry and Regional Centre for Research and Training in Child and Adolescent Psychiatry, Oslo, Norway
Eur Child Adolesc Psychiatry 10:135-42. 2001..On the item level, both the internalising and the externalising symptoms that best differentiated the children with SM from the controls support the notion of SM as an expression of social anxiety...
- Single photon emission tomography following posterior fossa surgery in patients with and without mutismYusuf Ersahin
Division of Pediatric Neurosurgery and Department of Nuclear Medicine, Ege University Faculty of Medicine, P K 30, Karsiyaka, Izmir 35602, Turkey
Childs Nerv Syst 18:318-25. 2002..a prospective study to investigate single photon emission tomography (SPECT) findings in patients with or without mutism who had undergone posterior fossa surgery...
- Brief report: transient mutism following posterior fossa surgery studied by single photon emission computed tomography (SPECT)Anna Clerico
Oncology Service, Pediatric Clinic University of Rome La Sapienza, Rome, Italy
Med Pediatr Oncol 38:445-8. 2002
- The evaluation and comparison of cerebellar mutism in children and adults after posterior fossa surgery: report of two adult cases and review of the literatureF Ildan
Department of Neurosurgery, Cukurova University, School of Medicine, Adana, Turkey
Acta Neurochir (Wien) 144:463-73. 2002Although there are some cases of cerebellar mutism in adults after posterior fossa surgery for cerebellar tumour it generally occurs in children. Reversible pathophsiology and the anatomical substrate of this syndrome still remain unclear...
- Non-specific markers of neurodevelopmental disorder/delay in selective mutism--a case-control studyH Kristensen
Nic Waal s Institute and Regional Centre for Child and Adolescent Psychiatry, Oslo, Norway
Eur Child Adolesc Psychiatry 11:71-8. 2002Selective mutism (SM) in children is frequently associated with language disorder/delay suggesting that neurobiological factors may be involved in the development of SM...
- Attention in selective mutism--an exploratory case-control studyBeate Oerbeck
Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Norway
J Anxiety Disord 22:548-54. 2008The aim of the study was to explore the association between selective mutism (SM) and attention. In SM social anxiety seems central but language impairment and motor problems are also reported...
- Is selective mutism associated with deficits in memory span and visual memory?: An exploratory case-control studyHanne Kristensen
Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway
Depress Anxiety 23:71-6. 2006Our main aim in this study was to explore the association between selective mutism (SM) and aspects of nonverbal cognition such as visual memory span and visual memory. Auditory-verbal memory span was also examined...
- [Functional pathophysiology of consciousness]Kurt A Jellinger
Institut für Klinische Neurobiologie, Wien
Neuropsychiatr 23:115-33. 2009..obtundation with tendency to fall asleep, 5. stupor, 6. coma and its subtypes, like akinetic mutism, apallic syndrome or persistent vegative state, locked-in syndrome, delirium, and catatonia...
- Brain death, states of impaired consciousness, and physician-assisted death for end-of-life organ donation and transplantationJoseph L Verheijde
Bioethics, Policy, and Law Program, Arizona State University, 300 East University Drive, Tempe, AZ, 85287, USA
Med Health Care Philos 12:409-21. 2009..then, clinical studies have defined a spectrum of states of impaired consciousness in human beings: coma, akinetic mutism (locked-in syndrome), minimally conscious state, vegetative state and brain death...
- Complications of posterior cranial fossa surgery--an institutional experience of 500 patientsArvind Dubey
Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA
Surg Neurol 72:369-75. 2009..The purposes of this retrospective study are to draw attention to the potential complications associated with posterior fossa surgery and to critically review the predisposing factors that might influence the complication rate...
- [Review of Creutzfeldt-Jakob disease and other prion diseases]S Zivkovic
Department of Neurology, University of Pittsburgh School of Medicine, Pennsylvania, USA
Rev Neurol 31:1171-9. 2000..Myoclonias, 2. Cortical blindness, 3. Pyramidal, extrapyramidal or cerebellar signs, 4. Akinetic mutism, or 5 Abnormal EEG...
- [Germinoma presenting with personality and socio-behavioral abnormalities may challenge differential diagnoses]Sotaro Hieda
Division of Neurology, Department of Internal Medicine, Showa University Northern Yokohama Hospital, Tokyo, Japan
Brain Nerve 60:949-53. 2008..Soon afterward, the patient collapsed into akinetic mutism and developed corresponding new lesions at the tegmentum of the midbrain...
- 14-3-3 protein, total tau and phosphorylated tau in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease and neurodegenerative disease in JapanKatsuya Satoh
The First Department of Internal Medicine, Nagasaki University Graduate School of Biomedical Science, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
Cell Mol Neurobiol 26:45-52. 2006..Patients with CJD usually become akinetic mutism within approximately 6 months...
- [A case of Asperger's disorder with catatonia originally suspected of being catatonic schizophrenia]Shinnosuke Saito
Department of Psychiatry, Jichi Medical University
Seishin Shinkeigaku Zasshi 113:241-7. 2011We report the case of an adolescent male who presented with mutism, immobility, catalepsy, and mannerisms...
- [Bilateral hyperintensity of the pulvinar in sporadic Creutzfeldt-Jakob disease]F J de la Torre Laviana
Hospital de Jerez, Jerez de la Frontera, Cadiz
Neurologia 24:202-8. 2009..A case of sporadic CJD with bilateral hyperintensity of pulvinar nucleus is described...
- Central neurotoxicity of cyclosporine in two children with nephrotic syndromeSophie Taque
Departement de medecine de l Enfant et de l Adolescent, CHU Rennes, Hopital Sud, 16 Boulevard de Bulgarie, 35056 Rennes, France
Pediatr Nephrol 19:276-80. 2004..The manifestations of CsA-related central neurotoxicity include confusion, aphasia, dystonias, akinetic mutism, parkinsonism, palsies, seizures, catatonia, coma, brain hemorrhage, and cortical blindness...
- [Case with difficulty in differentiating between transient neuroleptic malignant syndrome and catatonia after neuroleptic analgesia]Youichi Yanagawa
Department of Traumatology and Critical Care Medicine, National Defense Medical College, Tokorozawa 359 8513
Masui 59:235-7. 2010..After being transferred to our hospital, she exhibited immobility, mutism, rigidity, and catalepsy, and she was suspected of having lethal catatonia...
- The locked-in syndrome : what is it like to be conscious but paralyzed and voiceless?Steven Laureys
Neurology Department and Cyclotron Research Center, University of Liege, Sart Tilman B30, 4000 Liege, Belgium
Prog Brain Res 150:495-511. 2005..up, but remaining paralyzed and voiceless, superficially resembling patients in a vegetative state or akinetic mutism. In acute locked-in syndrome (LIS), eye-coded communication and evaluation of cognitive and emotional functioning ..
- Clonazepam withdrawal-induced catatoniaMark Brown
Dept of Psychiatry, Univ of Arizona, 1501 N Campbell Ave, P O Box 245002, Tucson, AZ 85724, USA
Psychosomatics 50:289-92. 2009..Catatonia is a often a complex syndrome. It has been divided into categories of simple and malignant, with the latter being a more severe form involving autonomic instability and/or fever and having a higher mortality rate...
- László Meduna's pilot studies with camphor inductions of seizures: the first 11 patientsGabor Gazdag
1st Department of Psychiatry and Psychiatric Rehabilitation, Jahn Ferenc Hospital, Koves utca, 1201 Budapest, Hungary
J ECT 25:3-11. 2009..Seizures of various durations (including missed seizures) and double (tardive) seizures were recorded. Mutism, refusal to eat requiring tube feeding, and other signs of catatonia dominated the psychopathology of 7 of the ..
- An autopsy case of frontotemporal dementia with severe dysarthria and motor neuron disease showing numerous basophilic inclusionsKenji Ishihara
Department of Neurology, Showa University School of Medicine, Hatanodai 1 5 8, Shinagawaku, Tokyo 142 8666, Japan
Neuropathology 26:447-54. 2006..Motor neuron signs then emerged, and the patient developed akinetic mutism approximately 2 years after the onset of the disease...
- Reversal of preoperative catatonic state by surgical resection of an adult-onset craniopharyngioma: case report and review of the literatureJustin Massengale
Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
Cogn Behav Neurol 22:67-71. 2009..To describe a case of a rare adult-onset craniopharyngioma presenting as rapidly progressive catatonia that was reversed after surgical resection of the tumor...
- [Management strategies for endemic goiter in developing countries]P Kouame
l Institut National de Santé Publique, l Université Victor Segalen, Bordeaux, France
Med Trop (Mars) 59:401-10. 1999..Endemic goiter is epidemiologically associated with cretinism, deaf-mutism, and mental retardation...
- Catatonia causing permanent cognitive impairment: a case studyIan W S Baker
Russell Cairns Unit, Radcliffe Infirmary, Oxford, OX2 6HE, England
Cogn Behav Neurol 18:141-3. 2005..We describe a case of psychogenic malignant catatonia resulting in permanent cognitive impairment...
- Treatment of chronic akinetic mutism with atomoxetine: subtraction analysis of brain f-18 fluorodeoxyglucose positron emission tomographic images before and after medication: a case reportYong Wook Kim
Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
Clin Neuropharmacol 33:209-11. 2010Akinetic mutism is a rare, complex neuropathologic disorder...
- A distinct phenotype of leg hyperreflexia in a Japanese family with Gerstmann-Sträussler-Scheinker syndrome (P102L)Takanori Takazawa
Department of Neurology, Toho University Omori Medical Center, Tokyo
Intern Med 49:339-42. 2010..She had verbal perseveration, somnolence and myoclonus of lower limbs, leading to akinetic mutism at 4 months after neuropsychiatric events...
- Creutzfeldt-Jakob disease with an M232R substitution: report of a patient showing slowly progressive disease with abundant plaque-like PrP deposits in the cerebellumHiroshi Shimizu
Department of Pathology, Brain Research Institute, Niigata University, Asahimachi, Chuo Ku, Niigata, Japan
Neuropathology 29:735-43. 2009..Myoclonus and akinetic mutism became evident 5 and 23 months after disease onset, respectively...
- Two patients with acute rotavirus encephalitis associated with cerebellar signs and symptomsSatoru Kobayashi
Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
Eur J Pediatr 169:1287-91. 2010..at onset and cerebellar signs and symptoms such as hypotonia, ataxia, dysmetria, and speech disorders, including mutism, slow speech, and dysarthria at convalescence...
- Coexistence of CJD and Alzheimer's disease: an autopsy case showing typical clinical features of CJDKuniaki Tsuchiya
Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Tokyo, Japan
Neuropathology 24:46-55. 2004..A neurological examination approximately 2 months after the disease onset revealed akinetic mutism, in addition to periodic synchronous discharges on electroencephalogram...
- [Distigmine bromide improves chronic intestinal pseudo-obstruction in a case of MELAS]Yoshiharu Nakae
Department of Neurology, Yokohama City University, School of Medicine
Rinsho Shinkeigaku 47:177-9. 2007..At the age of 34, he became akinetic mutism after nonconvulsive status epilepticus and needed enteral nutrition through a nasogasrtic tube...
- Spectrum of anterior cerebral artery territory infarction: clinical and MRI findingsE Kumral
Department of Neurology, Egg University, Izmir, Turkey
Eur J Neurol 9:615-24. 2002..there were three main clinical patterns depending on lesion side; left-side infarction (30 patients) consisting of mutism, transcortical motor aphasia, and hemiparesis with lower limb predominance; right side infarction (16 patients) ..
- The many varieties of catatoniaM Fink
Eur Arch Psychiatry Clin Neurosci 251:I8-13. 2001About 10% of patients with severe acute psychiatric illness exhibit a cluster of motor signs (mutism, negativism, rigidity, posturing, stereotypy, staring, etc.) that are identified as the syndrome of catatonia...
- The contribution of the cerebellum to speech production and speech perception: clinical and functional imaging dataHermann Ackermann
Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen
Cerebellum 6:202-13. 2007..or transcortical motor aphasia, have been noted in patients with vascular cerebellar lesions, and transient mutism following resection of posterior fossa tumors in children may develop into similar constellations...
- Neuropsychological features of rapidly progressive dementia in a patient with an atypical presentation of Creutzfeldt-Jakob DiseaseM Pachalska
Department of Medical Rehabilitation, Cracow Rehabilitation Center, Cracow, Poland
Med Sci Monit 7:1307-15. 2001..The mode of transmission and basic pathomechanism remain unclear. The clinical picture of CJD is highly diverse, producing a number of variants...
- BIPLEDs in akinetic mutism caused by bilateral anterior cerebral artery infarctionJ Nicolai
Department of Neurology and Clinical Neurophysiology, Ziekenhuis Leyenburg, Leyweg 275, 2545 CH Den Haag, The Netherlands
Clin Neurophysiol 112:1726-8. 2001Akinetic mutism is described as a result of many disorders. Bilateral infarction of the anterior cerebral artery (ACA) territory is reported rarely, however, often leading to akinetic mutism.
- Pick's disease with Pick bodies combined with progressive supranuclear palsy without tuft-shaped astrocytes: a clinical, neuroradiologic and pathological study of an autopsied caseLu Ning Wang
Department of Geriatric Neurology, Chinese PLA General Hospital, No 28 Fuxing road, Beijing 100853, China
Neuropathology 26:222-30. 2006..His condition gradually deteriorated and he developed mutism and became vegetative. The patient died from pneumonia 16 years after the onset of symptoms...
- The social anxiety spectrumFranklin R Schneier
Anxiety Disorders Clinic, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 69, New York, NY 10032, USA
Psychiatr Clin North Am 25:757-74. 2002..Strong evidence exists that at least some forms of shyness, avoidant personality disorder, and selective mutism lie on a social anxiety disorder spectrum...
- [An acute severe heat stroke patient showing abnormal diffuse high intensity of the cerebellar cortex in diffusion weighted image: a case report]Yusuke Fujioka
Department of Neurology, Nagoya Daini Red Cross Hospital
Rinsho Shinkeigaku 49:634-40. 2009..As the consciousness level ameliorated, he developed severe abulia and mutism, then cerebellar ataxic syndrome (viz. truncal ataxia, hypermetria, ataxic speech and nystagmus)...
- Neuroendoscopic approach to intraventricular lesionsM R Gaab
Department of Neurosurgery, Ernst Moritz Arndt University, Greifswald, Germany
J Neurosurg 88:496-505. 1998..The authors observed one case of meningitis, one of mutism, two of memory loss attributed to forniceal injury, one of transient trochlear palsy after a biopsy specimen of an ..
- Novel mutation of the PRNP gene of a clinical CJD caseKonstantia Kotta
Prion Disease Group, Laboratory of Pharmacology, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, Greece
BMC Infect Dis 6:169. 2006..Both isoforms are encoded by the same prion protein gene (PRNP), and the structural changes occur post-translationally. Certain mutations in the PRNP gene result in genetic TSEs or increased susceptibility to TSEs...
- Familial Creutzfeldt-Jakob disease with an R208H-129V haplotype and Kuru plaquesCéline Basset-Leobon
Institut national de la santé et de la recherche médicale U466 and Department of Pathology, Rangueil Hospital, Toulouse, France
Arch Neurol 63:449-52. 2006....
- [Microsurgical anatomy and clinical application of infratentorial supracerebellar keyhole approach]Qing Lan
Department of Neurosurgery, Second Affiliated Hospital of Suchow University, Suzhou 215004, China
Zhonghua Yi Xue Za Zhi 89:156-9. 2009..To explore the feasibility of applying the infratentorial supracerebellar keyhole approach for removing tumors of pineal region...
- [Creutzfeldt-Jakob disease: alterations in an isolated cortical signal in diffusion magnetic resonance imaging]F Moreno-Izco
Unidad de Neurologia, Hospital de Zumarraga, Zumarraga, Guipuzcoa, Espana
Rev Neurol 40:38-42. 2005....
- Attempting homicide by inserting sewing needle into the brain Report of 6 cases and review of literatureAbbas Amirjamshidi
Sina Hospital, Tehran University of Medical Sciences, Tehran 19584 678, Iran
Surg Neurol 72:635-41; discussion 641. 2009..This may deliver some evidences to the literature regarding management of further cases encountered by neurosurgeons...
- Opsoclonus-myoclonus syndrome in anti-N-methyl-D-aspartate receptor encephalitisMary Kurian
Department of Neurosciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Arch Neurol 67:118-21. 2010..Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis has been recently reported as autoimmune/paraneoplastic encephalitis, affecting mostly young females...
- [Approach to the patient in vegetative state. Part II: differential diagnosis]N Latronico
II Servizio di Anestesia e Rianimazione, Universita degli Studi di Brescia, Spedali Civili
Minerva Anestesiol 66:233-40. 2000..The akinetic mutism is a rare condition characterised by loss of speech and nearly absent bodily movements...
- Complications following endoscopic intracranial procedures in childrenGiuseppe Cinalli
Department of Pediatric Neurosurgery, Santobono Children s Hospital, Naples, Italy
Childs Nerv Syst 23:633-44. 2007..Nevertheless, severe, sometimes life-threatening, complications may occur during neuroendoscopic surgery, and the incidence and age specificity of complications in children have been underdescribed so far...
- Zuclopenthixol-induced neuroleptic malignant syndrome in an adolescent girlSerpil Erermis
Department of Child Psychiatry, Ege University, School of Medicine, Izmir, Turkey
Clin Toxicol (Phila) 45:277-80. 2007..Subsequently, she became increasingly agitated and confused, and developed diffuse muscular rigidity, mutism, tremor, tachycardia, diaphoresis, sialorrhea, and incontinence...
- Synaptic autoimmunity in disorders of memory, behavior, cognition and psychosisJosep Dalmau; Fiscal Year: 2010..proteins, including rapidly progressive psychosis;acute behavioral deficits, language dysfunction and mutism in children;and acute memory deficits and anterograde amnestic syndromes, we will perform 2 aims: 1) Determine the ..
- Genetics of Anxiety DisordersJoel Gelernter; Fiscal Year: 2013..identified RGS2 as a gene that can influence anxiety phenotypes, and CNTNAP2 as a gene that can affect selective mutism risk...
- Functional Architecture of Human Speech Motor CortexEdward Chang; Fiscal Year: 2011..of speech production has major implications for understanding a large number of communication disorders including mutism, stuttering, apraxia of speech, and aphasia...
- Exploring the role of the central amygdala in vocalizationIAN CHRISTOPHER HALL; Fiscal Year: 2013..could make important contributions to the treatment of communication disorders, such as speech aphasias, selective mutism, and stuttering, and social cognition disorders, such as Asperger's syndrome and autism spectrum disorders.
- Benzodiazepine Analogs as Novel Treatments for CatatoniaHOWARD P SARD; Fiscal Year: 2012DESCRIPTION (provided by applicant): Catatonia is a widespread and serious syndrome characterized by mutism, stupor, refusal to eat or drink, posturing, and hypokinesis, and affects a broad range of psychiatric and other patients in the ..
- Improving Outcomes in Pharmacotherapy of Social PhobiaMurray Stein; Fiscal Year: 2009..It thus directly addresses a critical public health issue that adversely affects a substantial proportion of the population. ..
- IMPROVING CARE FOR PANIC DISORDER IN PRIMARY CAREMurray Stein; Fiscal Year: 2002..abstract_text> ..
- Preventing Psychiatric Sequelae of Traumatic InjuryMurray Stein; Fiscal Year: 2003..Findings will provide justification for and information about optimal parameters (e.g., subject selection; sample size; dose and duration) for a future randomized controlled trial (RCT). ..
- Pharmacological fMRI to Identify New Anxiolytics: A Human BioassayMurray Stein; Fiscal Year: 2008..Enhancing the development of new treatments for anxiety is a public health priority. The projects proposed in this application have the potential to achieve this important aim. [unreadable] [unreadable] [unreadable]..
- Neural circuitry of submissive behavior and treatment response in social anxietyFranklin Schneier; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Functional Changes Induced By Sleep DeprivationGiulio Tononi; Fiscal Year: 2004..These studies should provide insights into the molecular consequences of prolonged sleep deprivation and chronic insomnia and suggest new therapeutic approaches. ..
- Dopamine function in social phobia & related conditionsFranklin Schneier; Fiscal Year: 2006..Better understanding of the neurocircuitry associated with GSP holds promise for improving diagnosis and treatment strategies. ..
- Primary Progessive Aphasia: Cognition, Anatomy and ProgressionMARIA LUISA GORNO TEMPINI; Fiscal Year: 2008..will increase our knowledge about the neural basis of speech and language functions and provide crucial data for the diagnosis of neurodegenerative diseases in their early stages, when treatment can be most effective ..
- Local Sleep Regulation and Brain PlasticityGiulio Tononi; Fiscal Year: 2010..Thus, they are highly relevant to the mission of MINDS, NIMH, and NHLBI. ..
- Latent Mobility Abnormalities and DisabilityJoe Verghese; Fiscal Year: 2006..unreadable] [unreadable]..
- Childhood Bilingualism & Developmental PsychopathologyCLAUDIO TOPPELBERG; Fiscal Year: 2006..The ultimate goal is to create a solid, leading, lifelong program of research in the fields of Childhood Bilingualism and Developmental Psychopathology. ..
- Combination Treatment for PTSD After the WTC AttackFranklin Schneier; Fiscal Year: 2008..Findings may enhance public health through the study of maximization of treatment response for this serious and common psychiatric disorder. ..
- Integrated Behavioral Treatment for Selective MutismR Bergman; Fiscal Year: 2007This is an R34 application to support the development of a standardized behavioral treatment program for selective mutism (SM) in young children aged 4-8 years old...