gambling

Summary

Summary: An activity distinguished primarily by an element of risk in trying to obtain a desired goal, e.g., playing a game of chance for money.

Top Publications

  1. pmc Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, CMHC, 34 Park Street, New Haven, CT 06405, USA
    Psychopharmacology (Berl) 219:469-90. 2012
  2. ncbi The feedback-related negativity reflects the binary evaluation of good versus bad outcomes
    Greg Hajcak
    Department of Psychology, University of Delaware, Newark, DE, USA
    Biol Psychol 71:148-54. 2006
  3. ncbi Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions
    A Bechara
    Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience, University of Iowa College of Medicine, Iowa City, Iowa, USA
    Brain 123:2189-202. 2000
  4. ncbi Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies
    Antonio Verdejo-Garcia
    Pharmacology Research Unit, Institut Municipal d Investigacio Medica, Barcelona Biomedical Research Park, Dr Aiguader 88, 08003 Barcelona, Spain
    Neurosci Biobehav Rev 32:777-810. 2008
  5. ncbi Independent coding of reward magnitude and valence in the human brain
    Nick Yeung
    Center for the Study of Brain, Mind, and Behavior, Department of Psychology, Princeton University, Princeton, New Jersey 08544, USA
    J Neurosci 24:6258-64. 2004
  6. ncbi Decision-making deficits of korsakoff patients in a new gambling task with explicit rules: associations with executive functions
    Matthias Brand
    Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany
    Neuropsychology 19:267-77. 2005
  7. pmc Cortical substrates for exploratory decisions in humans
    Nathaniel D Daw
    Gatsby Computational Neuroscience Unit, University College London UCL, Alexandra House, 17 Queen Square, London WC1N 3AR, UK
    Nature 441:876-9. 2006
  8. ncbi It's worse than you thought: the feedback negativity and violations of reward prediction in gambling tasks
    Greg Hajcak
    Department of Psychology, Stony Brook University, Stony Brook, NY 11794 9500, USA
    Psychophysiology 44:905-12. 2007
  9. ncbi Pathological gambling in Parkinson's disease improves on chronic subthalamic nucleus stimulation
    Claire Ardouin
    Departement de Neurologie, CHU Grenoble, INSERM U318, Universite Joseph Fourier, Grenoble, France
    Mov Disord 21:1941-6. 2006
  10. ncbi Distorted expectancy coding in problem gambling: is the addictive in the anticipation?
    Ruth J van Holst
    Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Biol Psychiatry 71:741-8. 2012

Detail Information

Publications370 found, 100 shown here

  1. pmc Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, CMHC, 34 Park Street, New Haven, CT 06405, USA
    Psychopharmacology (Berl) 219:469-90. 2012
    Pathological gambling (PG) has recently been considered as a "behavioral" or nonsubstance addiction...
  2. ncbi The feedback-related negativity reflects the binary evaluation of good versus bad outcomes
    Greg Hajcak
    Department of Psychology, University of Delaware, Newark, DE, USA
    Biol Psychol 71:148-54. 2006
    ..In both experiments, participants performed simple gambling tasks in which they could receive a range of potential outcomes on each trial...
  3. ncbi Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions
    A Bechara
    Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience, University of Iowa College of Medicine, Iowa City, Iowa, USA
    Brain 123:2189-202. 2000
    On a gambling task that models real-life decisions, patients with bilateral lesions of the ventromedial prefrontal cortex (VM) opt for choices that yield high immediate gains in spite of higher future losses...
  4. ncbi Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies
    Antonio Verdejo-Garcia
    Pharmacology Research Unit, Institut Municipal d Investigacio Medica, Barcelona Biomedical Research Park, Dr Aiguader 88, 08003 Barcelona, Spain
    Neurosci Biobehav Rev 32:777-810. 2008
    ..Within each of these three lines of enquiry, there is accumulating evidence that impulsivity is a pre-existing vulnerability marker for SUDs...
  5. ncbi Independent coding of reward magnitude and valence in the human brain
    Nick Yeung
    Center for the Study of Brain, Mind, and Behavior, Department of Psychology, Princeton University, Princeton, New Jersey 08544, USA
    J Neurosci 24:6258-64. 2004
    ..The present study investigated the properties of these components in a simple gambling game that required participants to choose between cards that were unpredictably associated with monetary gains ..
  6. ncbi Decision-making deficits of korsakoff patients in a new gambling task with explicit rules: associations with executive functions
    Matthias Brand
    Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany
    Neuropsychology 19:267-77. 2005
    Decision-making deficits reflected by risky decisions in gambling tasks have been associated with frontal lobe dysfunctions in various neurologic and psychiatric populations...
  7. pmc Cortical substrates for exploratory decisions in humans
    Nathaniel D Daw
    Gatsby Computational Neuroscience Unit, University College London UCL, Alexandra House, 17 Queen Square, London WC1N 3AR, UK
    Nature 441:876-9. 2006
    ..Here we show, in a gambling task, that human subjects' choices can be characterized by a computationally well-regarded strategy for ..
  8. ncbi It's worse than you thought: the feedback negativity and violations of reward prediction in gambling tasks
    Greg Hajcak
    Department of Psychology, Stony Brook University, Stony Brook, NY 11794 9500, USA
    Psychophysiology 44:905-12. 2007
    ..To further examine this issue, participants in the present studies made reward predictions on each trial of a gambling task where objective reward probability was indicated by a cue...
  9. ncbi Pathological gambling in Parkinson's disease improves on chronic subthalamic nucleus stimulation
    Claire Ardouin
    Departement de Neurologie, CHU Grenoble, INSERM U318, Universite Joseph Fourier, Grenoble, France
    Mov Disord 21:1941-6. 2006
    Pathological gambling (PG) related to dopaminergic treatment in Parkinson's disease (PD) is part of a spectrum of behavioral disorders called the dopamine dysregulation syndrome (DDS)...
  10. ncbi Distorted expectancy coding in problem gambling: is the addictive in the anticipation?
    Ruth J van Holst
    Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Biol Psychiatry 71:741-8. 2012
    ..Pathologic gamblers are known to have abnormal neural responses associated with experiencing monetary wins and losses. However, neural responsiveness during reward and loss expectations in pathologic gamblers has not yet been investigated...
  11. pmc Altered brain activity during reward anticipation in pathological gambling and obsessive-compulsive disorder
    Jung Seok Choi
    Department of Psychiatry, Seoul National University College of Medicine, Korea
    PLoS ONE 7:e45938. 2012
    Pathological gambling (PG) and obsessive-compulsive disorder (OCD) are conceptualized as a behavioral addiction, with a dependency on repetitive gambling behavior and rewarding effects following compulsive behavior, respectively...
  12. ncbi The somatic marker hypothesis: a critical evaluation
    Barnaby D Dunn
    MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
    Neurosci Biobehav Rev 30:239-71. 2006
    ..Evidence for the SMH is largely based on performance on the Iowa Gambling Task (IGT; [Bechara, A., Tranel, D., Damasio, H., Damasio, A.R., 1996...
  13. pmc The neural substrates of probabilistic and intertemporal decision making
    Bethany J Weber
    Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA
    Brain Res 1234:104-15. 2008
    ..These results indicate that there are differences in the patterns of brain activation evoked by risky and intertemporal choices, suggesting that the two domains utilize at least partially distinct sets of cognitive processes...
  14. ncbi Using STN DBS and medication reduction as a strategy to treat pathological gambling in Parkinson's disease
    Fabio Bandini
    Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via A De Toni 5, 16132 Genoa, Italy
    Parkinsonism Relat Disord 13:369-71. 2007
    We describe two patients with Parkinson's disease (PD) who developed clinical criteria of pathological gambling addiction in the setting of increased dopamine replacement therapy (levodopa and dopamine agonist medications)...
  15. ncbi The involvement of the orbitofrontal cortex in the experience of regret
    Nathalie Camille
    Institut des Sciences Cognitives, CNRS, 67, Boulevard Pinel 69675 Bron, France
    Science 304:1167-70. 2004
    ..These emotions are mediated by a cognitive process known as counterfactual thinking. By manipulating a simple gambling task, we characterized a subject's choices in terms of their anticipated and actual emotional impact...
  16. pmc Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study
    T D L Steeves
    Movement Disorders Centre, Toronto Western Hospital, UHN, Ontario, Canada
    Brain 132:1376-85. 2009
    Pathological gambling is an impulse control disorder reported in association with dopamine agonists used to treat Parkinson's disease...
  17. ncbi Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward?
    Antoine Bechara
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Neuropsychologia 40:1690-705. 2002
    On a decision-making instrument known as the "gambling task" (GT), a subgroup of substance dependent individuals (SDI) opted for choices that yield high immediate gains in spite of higher future losses...
  18. ncbi The P300 and reward valence, magnitude, and expectancy in outcome evaluation
    Yan Wu
    Research Center for Learning Science, Southeast University, Nanjing 210096, China
    Brain Res 1286:114-22. 2009
    ..manipulated orthogonally reward valence, reward magnitude, and expectancy towards reward magnitude in a monetary gambling task and observed both the valence and the magnitude effects on the P300, but only when the amount of reward was ..
  19. ncbi Dissociable systems for gain- and loss-related value predictions and errors of prediction in the human brain
    Juliana Yacubian
    Department of Systems Neuroscience, NeuroImage Nord, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
    J Neurosci 26:9530-7. 2006
    ..Prevalence of either part might render expectations more positive or negative, which could contribute to the pathophysiology of mood disorders like major depression...
  20. ncbi A critical review of sex differences in decision-making tasks: focus on the Iowa Gambling Task
    Ruud van den Bos
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Behav Brain Res 238:95-108. 2013
    It has been observed that men and women show performance differences in the Iowa Gambling Task (IGT), a task of decision-making in which subjects through exploration learn to differentiate long-term advantageous from long-term ..
  21. pmc Gambling for Gatorade: risk-sensitive decision making for fluid rewards in humans
    Benjamin Y Hayden
    Department of Neurobiology and Center for Neuroeconomic Studies, Duke University School of Medicine, Durham, NC, 27710, USA
    Anim Cogn 12:201-7. 2009
    ..Comparison with decisions made by monkeys for juice in a similar task revealed highly similar gambling styles...
  22. ncbi Altered neural reward representations in pathological gamblers revealed by delay and probability discounting
    Stephan F Miedl
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Arch Gen Psychiatry 69:177-86. 2012
    ..The neural basis of excessive delay discounting and reduced risk sensitivity of pathological gamblers with a particular focus on subjective neural reward representations has not been previously examined...
  23. ncbi Prefrontal cortex activity is reduced in gambling and nongambling substance users during decision-making
    Jody Tanabe
    Department of Radiology, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
    Hum Brain Mapp 28:1276-86. 2007
    ..Performance on a widely used test of decision-making, the Iowa Gambling Task (IGT), can discriminate controls from persons with ventral medial frontal lesions, substance-dependence, and ..
  24. pmc Association of dopamine agonist use with impulse control disorders in Parkinson disease
    Daniel Weintraub
    Department of Psychiatry, University of Pennsylvania, and Parkinson s Disease Research, Education, and Clinical Center, USA
    Arch Neurol 63:969-73. 2006
    ..To determine the frequency and correlates of impulse control disorders (ICDs) in Parkinson disease (PD)...
  25. ncbi Distinct roles of prefrontal cortical subregions in the Iowa Gambling Task
    Natalia S Lawrence
    King s College London, Section of Neuroscience and Emotion, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Cereb Cortex 19:1134-43. 2009
    The Iowa Gambling Task (IGT) assesses decision-making under initially ambiguous conditions...
  26. ncbi Cigarette smoking is associated with increased severity of gambling problems in treatment-seeking gamblers
    Nancy M Petry
    Department of Psychiatry, University of Connecticut Health Center, Farmington 06030 3944, USA
    Addiction 97:745-53. 2002
    Cigarette smoking and gambling often co-occur, but very little is known about smoking or its correlates in disordered gamblers...
  27. ncbi Tracking the hemodynamic responses to reward and punishment in the striatum
    M R Delgado
    Department of Neuroscience, University of Pittsburgh and Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15260, USA
    J Neurophysiol 84:3072-7. 2000
    ..Activation was sustained following a reward feedback, but decreased below baseline following a punishment feedback...
  28. pmc Diminished frontostriatal activity during processing of monetary rewards and losses in pathological gambling
    Iris M Balodis
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Biol Psychiatry 71:749-57. 2012
    Mesocorticolimbic neurocircuitry and impulsivity have both been implicated in pathological gambling (PG) and in reward processing...
  29. ncbi Why gamblers fail to win: a review of cognitive and neuroimaging findings in pathological gambling
    Ruth J van Holst
    Academic Medical Center, University of Amsterdam, Department of Psychiatry, Amsterdam Institute for Addiction Research, Amsterdam, The Netherlands
    Neurosci Biobehav Rev 34:87-107. 2010
    The purpose of this review is to gain more insight in the neuropathology of pathological gambling (PG) and problem gambling, and to discuss challenges in this research area...
  30. pmc The Iowa Gambling Task in fMRI images
    Xiangrui Li
    Department of Psychology, Dana and David Dornsife Cognitive Neuroscience Imaging Center, University of Southern California, Los Angeles, 90089 2520, USA
    Hum Brain Mapp 31:410-23. 2010
    The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision-making impairments in several neurological and psychiatric populations...
  31. ncbi Neural response to reward anticipation under risk is nonlinear in probabilities
    Ming Hsu
    Beckman Institute for Advanced Science and TechnologyUniversity of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Neurosci 29:2231-7. 2009
    ....
  32. ncbi An fMRI study of reward-related probability learning
    M R Delgado
    Department of Psychology, New York University, New York, NY 10003, USA
    Neuroimage 24:862-73. 2005
    ..Using a gambling paradigm, in which affective feedback (reward and punishment) followed simple, random guesses on a trial by trial ..
  33. ncbi Age differences in affective decision making as indexed by performance on the Iowa Gambling Task
    Elizabeth Cauffman
    Department of Psychology and Social Behavior, University of California, Irvine, 3340 Social Ecology II, Irvine, CA 92687, USA
    Dev Psychol 46:193-207. 2010
    ..diverse sample of 901 individuals between the ages of 10 and 30 were administered a modified version of the Iowa Gambling Task, which is designed to measure affective decision making...
  34. ncbi Enhanced BDNF serum levels in patients with severe pathological gambling
    Francesco Angelucci
    IRCCS Santa Lucia Foundation, Department of Clinical and Behavioural Neurology, Rome, Italy Institute of Psychiatry, Catholic University, Rome, Italy
    Addict Biol 18:749-51. 2013
    Although the pathophysiology of gambling is unknown, an involvement of midbrain dopaminergic pathway has been hypothesized...
  35. ncbi The medial frontal cortex and the rapid processing of monetary gains and losses
    William J Gehring
    Department of Psychology, University of Michigan, 525 East University, Ann Arbor, MI 48109 1109, USA
    Science 295:2279-82. 2002
    ..occurs within 265 milliseconds after outcome stimuli that inform human participants about gains and losses in a gambling task...
  36. ncbi Pathological gambling is linked to reduced activation of the mesolimbic reward system
    Jan Reuter
    NeuroImage Nord, Department of Neurology, Hamburg University Hospital Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Nat Neurosci 8:147-8. 2005
    By analogy to drug dependence, it has been speculated that the underlying pathology in pathological gambling is a reduction in the sensitivity of the reward system...
  37. pmc Big losses lead to irrational decision-making in gambling situations: relationship between deliberation and impulsivity
    Yuji Takano
    SHIMOJO Implicit Brain Function Project, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Atsugi shi, Kanagawa, Japan
    PLoS ONE 5:e9368. 2010
    In gambling situations, we found a paradoxical reinforcing effect of high-risk decision-making after repeated big monetary losses. The computerized version of the Iowa Gambling Task (Bechara et al...
  38. ncbi Association of functional variants in the dopamine D2-like receptors with risk for gambling behaviour in healthy Caucasian subjects
    Daniela S S Lobo
    Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Biol Psychol 85:33-7. 2010
    Pathological gambling (PG) is an impulse control disorder with suggestive genetic vulnerability component...
  39. ncbi Decision-making and cognitive abilities: A review of associations between Iowa Gambling Task performance, executive functions, and intelligence
    Maggie E Toplak
    Department of Psychology, LaMarsh Centre for Research on Violence and Conflict Resolution, York University, Canada
    Clin Psychol Rev 30:562-81. 2010
    The Iowa Gambling Task (IGT) has been used to study decision-making differences in many different clinical and developmental samples...
  40. ncbi Mesolimbic dopamine release is linked to symptom severity in pathological gambling
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Neuroimage 60:1992-9. 2012
    ..Human reward-seeking gambling behavior, and especially pathological gambling, has been presumed to be modulated by brain dopamine.
  41. pmc Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making
    L Clark
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, UK
    Brain 131:1311-22. 2008
    ..g. the Iowa Gambling Task)...
  42. pmc Drug-induced deactivation of inhibitory networks predicts pathological gambling in PD
    T van Eimeren
    Division of Brain, Imaging and Behaviour Systems Neuroscience, BIB SN, Toronto Western Research Institute, University of Toronto, Canada
    Neurology 75:1711-6. 2010
    Some patients with Parkinson disease (PD) develop pathological gambling when treated with dopamine agonists (DAs)...
  43. ncbi Should addictive disorders include non-substance-related conditions?
    Marc N Potenza
    Yale University School of Medicine, New Haven, CT, USA
    Addiction 101:142-51. 2006
    ..In anticipation of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), to consider whether addictive disorders should include non-substance use disorders...
  44. pmc Frames, biases, and rational decision-making in the human brain
    Benedetto De Martino
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1 3AR, UK
    Science 313:684-7. 2006
    ..This finding highlights the importance of incorporating emotional processes within models of human choice and suggests how the brain may modulate the effect of these biasing influences to approximate rationality...
  45. ncbi Construct validity of the Iowa Gambling Task
    Melissa T Buelow
    Department of Psychology, Ohio University, Athens, OH, USA
    Neuropsychol Rev 19:102-14. 2009
    The Iowa Gambling Task (IGT) was created to assess real-world decision making in a laboratory setting and has been applied to various clinical populations (i.e...
  46. ncbi Drug abusers show impaired performance in a laboratory test of decision making
    S Grant
    Intramural Research Program, National Institute on Drug Abuse, Brain Imaging Center, 5500 Nathan Shock Drive, MD 21224, Baltimore, USA
    Neuropsychologia 38:1180-7. 2000
    ..evaluation of long-term outcomes in the presence of a complex set of mixed reward/punishment contingencies (the Gambling Task)...
  47. ncbi Functional activity related to risk anticipation during performance of the Iowa Gambling Task
    Hiroki Fukui
    Department of Neuropsychiatry, Kyoto University Graduate School of Medicine, Kyoto University, Kyoto 606, Japan
    Neuroimage 24:253-9. 2005
    Risk anticipation is an important cognitive/emotional component of decision making. The Iowa Gambling Task [Bechara, A., Damasio, A.R., Damasio, H., Anderson, S.W., 1994...
  48. ncbi Prevalence of comorbid disorders in problem and pathological gambling: systematic review and meta-analysis of population surveys
    Felicity K Lorains
    Problem Gambling Research and Treatment Centre, School of Primary Health Care, Monash University, Notting Hill, Victoria, Australia
    Addiction 106:490-8. 2011
    ....
  49. ncbi Decisions under ambiguity and decisions under risk: correlations with executive functions and comparisons of two different gambling tasks with implicit and explicit rules
    Matthias Brand
    Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany
    J Clin Exp Neuropsychol 29:86-99. 2007
    We conducted two experiments with healthy subjects to investigate the possible relationships between Iowa Gambling Task (IGT) performance and executive functions as well as IGT performance and decision-making in a task with explicit rules,..
  50. pmc Dopamine agonists diminish value sensitivity of the orbitofrontal cortex: a trigger for pathological gambling in Parkinson's disease?
    Thilo van Eimeren
    Division of Brain, Imaging and Behaviour Systems Neuroscience, BIB SN, Toronto Western Research Institute, University of Toronto, Toronto, ON, Canada
    Neuropsychopharmacology 34:2758-66. 2009
    The neurobehavioral underpinnings of pathological gambling are not well understood. Insight might be gained by understanding pharmacological effects on the reward system in patients with Parkinson's disease (PD)...
  51. ncbi Frontal lobe dysfunction in pathological gambling patients
    Paolo Cavedini
    Department of Neuropsychiatric Sciences, San Raffaele Scientific Institute, Vita Salute San Raffaele University, 20 via Stamira d Ancona, Milan 20127, Italy
    Biol Psychiatry 51:334-41. 2002
    Limited data are available about the validity of the diagnosis of pathological gambling (PG) and about the etiology and the efficacy of different treatment strategies of this disorder; however, similarities in decision-making behavior ..
  52. ncbi Effects of anticipatory stress on decision making in a gambling task
    S D Preston
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
    Behav Neurosci 121:257-63. 2007
    ..Participants played the Iowa Gambling Task, during which only experimental participants anticipated giving a public speech (A. Bechara, D...
  53. ncbi Comorbidity of DSM-IV pathological gambling and other psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Nancy M Petry
    Department of Psychiatry, University of Connecticut Health Center, Farmington, CT, USA
    J Clin Psychiatry 66:564-74. 2005
    To present nationally representative data on lifetime prevalence and comorbidity of pathological gambling with other psychiatric disorders and to evaluate sex differences in the strength of the comorbid associations.
  54. pmc Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task
    K I Bolla
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neuroimage 19:1085-94. 2003
    ..abusers show alterations in normalized cerebral blood flow (rCBF) in the OFC using PET with (15)O during the Iowa Gambling Task (a decision-making task)...
  55. ncbi Pathological gambling in Parkinson's disease: risk factors and differences from dopamine dysregulation. An analysis of published case series
    David A Gallagher
    Department of Clinical Neurosciences, Royal Free and University College Medical School, London, United Kingdom
    Mov Disord 22:1757-63. 2007
    Pathological gambling (PG) has been reported as a complication of the treatment of Parkinson's disease (PD)...
  56. pmc Brain signatures of monetary loss and gain: outcome-related potentials in a single outcome gambling task
    Chella Kamarajan
    Henri Begleiter Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Behav Brain Res 197:62-76. 2009
    This study evaluates the event-related potential (ERP) components in a single outcome gambling task that involved monetary losses and gains. The participants were 50 healthy young volunteers (25 males and 25 females)...
  57. ncbi Toward a rodent model of the Iowa gambling task
    Ruud van den Bos
    Faculty of Veterinary Medicine, Ethology and Welfare, Utrecht University, Yalelaan 2, NL 3584 CM, Utrecht, The Netherlands
    Behav Res Methods 38:470-8. 2006
    The Iowa gambling task in humans is, in principle, suited for the study of the long-term efficiency of behavior in a biologically relevant context...
  58. ncbi The additive effect of neurotransmitter genes in pathological gambling
    D E Comings
    Department of Medical Genetics, City of Hope Medical Center, Duarte, CA 91010, USA
    Clin Genet 60:107-16. 2001
    As access to gambling increases there is a corresponding increase in the frequency of addiction to gambling, known as pathological gambling...
  59. ncbi Brain, emotion and decision making: the paradigmatic example of regret
    Giorgio Coricelli
    Neuropsychology Group, Institut des Sciences Cognitives, Centre National de la Recherche Scientifique, 67 Boulevard Pinel, 69675 Bron, France
    Trends Cogn Sci 11:258-65. 2007
    ..Moreover, affective consequences can induce specific mechanisms of cognitive control of the choice processes, involving reinforcement or avoidance of the experienced behavior...
  60. ncbi Anxiety impairs decision-making: psychophysiological evidence from an Iowa Gambling Task
    Andrei C Miu
    Program of Cognitive Neuroscience, Department of Psychology, Babes Bolyai University, 37 Republicii, Cluj Napoca, CJ 400015, Romania
    Biol Psychol 77:353-8. 2008
    Using the Iowa Gambling Task (IGT) and psychophysiological correlates of emotional responses (i.e., heart rate and skin conductance), we investigate the effects of trait anxiety (TA) on decision-making...
  61. ncbi Co-occurrence of addictive behaviours: personality factors related to substance use, gambling and computer gaming
    Birte Walther
    Institute for Therapy and Health Research, Kiel, Germany
    Eur Addict Res 18:167-74. 2012
    To investigate co-occurrence and shared personality characteristics of problematic computer gaming, problematic gambling and substance use.
  62. ncbi Context-dependent cortical activation in response to financial reward and penalty: an event-related fMRI study
    Yuko Akitsuki
    Department of Psychiatry, NICHe, Tohoku University Graduate School of Medicine, Aoba 10, Aramaki, Aoba ku, Sendai, Miyagi 980 8579, Japan
    Neuroimage 19:1674-85. 2003
    ..An event-related fMRI technique was used to assess neural responses to financial reward and penalty during a simple gambling task. We attempted to determine whether brain activities are dependent on the unique context of an event sequence...
  63. ncbi Adolescents' performance on the Iowa Gambling Task: implications for the development of decision making and ventromedial prefrontal cortex
    Catalina J Hooper
    Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN, USA
    Dev Psychol 40:1148-58. 2004
    Healthy adolescents (79 girls, 66 boys), ages 9-17, completed the Iowa Gambling Task (IGT; A. Bechara, A. R. Damasio, H. Damasio, & S. W...
  64. pmc Proactive motor control reduces monetary risk taking in gambling
    Frederick Verbruggen
    Psychology, College of Life and Environmental Sciences, Washington Singer Laboratories, Streatham Campus, Exeter, EX4 4QG, United Kingdom
    Psychol Sci 23:805-15. 2012
    ..by the executive system after disruption of the right prefrontal cortex leads to increased risk taking in gambling because superficially attractive-but risky-choices are not suppressed...
  65. ncbi Electronic gaming machines: are they the 'crack-cocaine' of gambling?
    Nicki Dowling
    School of Health Sciences, RMIT University, Bundoora, Australia
    Addiction 100:33-45. 2005
    There is a general view that electronic gaming is the most 'addictive' form of gambling, in that it contributes more to causing problem gambling than any other gambling activity...
  66. ncbi Impulsivity and decision making
    Ariane Zermatten
    Cognitive Psychopathology and Neuropsychology Unit, University of Geneva, Geneva, Switzerland
    J Nerv Ment Dis 193:647-50. 2005
    ..self-report questionnaire evaluating impulsivity as well as a task measuring decision-making processes, the Iowa Gambling Task...
  67. pmc Neurobiology of gambling behaviors
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Curr Opin Neurobiol 23:660-7. 2013
    For many, gambling is a recreational activity that is performed periodically without ill effects, but for some, gambling may interfere with life functioning...
  68. ncbi Similar hyporesponsiveness of the dorsomedial prefrontal cortex in problem gamblers and heavy smokers during an inhibitory control task
    Michiel B de Ruiter
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Drug Alcohol Depend 121:81-9. 2012
    Behavioral addictions like pathological gambling share many clinical characteristics with substance dependence. In addition, both types of disorders are associated with impairments in inhibitory control...
  69. pmc Memantine shows promise in reducing gambling severity and cognitive inflexibility in pathological gambling: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 212:603-12. 2010
    Although pathological gambling (PG) is relatively common, pharmacotherapy research for PG is limited...
  70. ncbi Decision making in Parkinson's disease: Analysis of behavioral and physiological patterns in the Iowa gambling task
    Mutsutaka Kobayakawa
    Department of Neurology, Showa University School of Medicine, Tokyo, Japan
    Mov Disord 23:547-52. 2008
    ..The purpose of the present study was to examine the decision making of PD patients performing the Iowa Gambling Task (IGT). We recruited a large number of early, nondemented PD patients for the IGT...
  71. ncbi Problem gamblers exhibit reward hypersensitivity in medial frontal cortex during gambling
    Scott A K Oberg
    The University of Lethbridge, Lethbridge, AB, Canada
    Neuropsychologia 49:3768-75. 2011
    Problem gambling (PG) is increasingly conceptualized as an addiction akin to substance abuse, rather than an impulse control disorder, however the mechanism of addiction remains unclear...
  72. pmc Decision making and binge drinking: a longitudinal study
    Anna E Goudriaan
    University of Missouri Columbia, and the Midwest Alcoholism Research Center, Columbia, Missouri 65211, USA
    Alcohol Clin Exp Res 31:928-38. 2007
    Behavioral decision making, as measured by the Iowa Gambling Task (IGT) is found to be diminished in individuals with substance dependence and other types of disinhibitory psychopathology...
  73. pmc Neurobehavioral evidence for the "Near-Miss" effect in pathological gamblers
    Reza Habib
    Department of Psychology, Southern Illinois University, Carbondale, IL 62901, USA
    J Exp Anal Behav 93:313-28. 2010
    ..Such a translational approach to the study of gambling behavior may be considered an example that gives life to B. F...
  74. pmc Approach-avoidance processes contribute to dissociable impacts of risk and loss on choice
    Nicholas D Wright
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1N 3BG, United Kingdom
    J Neurosci 32:7009-20. 2012
    ..We demonstrate this independence in a gambling task, by selectively reversing a loss-induced effect (causing more gambling for gains than losses and the reverse)..
  75. ncbi Risky business: emotion, decision-making, and addiction
    Antoine Bechara
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Gambl Stud 19:23-51. 2003
    ..mechanisms of decision-making has direct implications for understanding disorders of addiction and pathological gambling, and the switch from a controlled to uncontrolled and compulsive behavior...
  76. ncbi The Balloon Analogue Risk Task (BART) differentiates smokers and nonsmokers
    C W Lejuez
    Department of Psychology, University of Maryland, College Park 20742, USA
    Exp Clin Psychopharmacol 11:26-33. 2003
    ..In this study, the authors compared the ability of 2 behavioral measures of risk taking, the Bechara Gambling Task (BGT) and the Balloon Analogue Risk Task (BART), to differentiate smokers and nonsmokers...
  77. pmc Measurement of fine particles and smoking activity in a statewide survey of 36 California Indian casinos
    Ruo Ting Jiang
    Department of Civil and Environmental Engineering, Stanford University, Stanford, California 94305, USA
    J Expo Sci Environ Epidemiol 21:31-41. 2011
    ..Elevated PM₂.₅ concentrations in casinos can be attributed primarily to SHS. Average PM₂.₅ concentrations during 0.5-1 h visits to smoking areas exceeded 35 μg/m³ for 90% of the casino visits...
  78. pmc Gambling severity predicts midbrain response to near-miss outcomes
    Henry W Chase
    School of Psychology, University of Nottingham, Nottingham NG7 2RD, United Kingdom
    J Neurosci 30:6180-7. 2010
    b>Gambling is a common recreational activity that becomes dysfunctional in a subset of individuals, with DSM "pathological gambling" regarded as the most severe form...
  79. ncbi Grouping and gambling: a Gestalt approach to understanding the gambler's fallacy
    Christopher J R Roney
    Department of Psychology, Kings College, University of Western Ontario, London, Ontario
    Can J Exp Psychol 57:69-75. 2003
    ..Discussion centres on the processes underlying the gambler's fallacy and practical implications of these findings...
  80. ncbi Executive functions and risky decision-making in patients with opiate dependence
    Matthias Brand
    Department of Physiological Psychology, University of Bielefeld, Germany
    Drug Alcohol Depend 97:64-72. 2008
    ..However, it remains unclear whether patients addicted to opiates show impaired decision-making on gambling tasks that specify explicit rules for rewards and punishments and provide information about probabilities ..
  81. ncbi Pathologic gambling in patients with restless legs syndrome treated with dopaminergic agonists
    M Tippmann-Peikert
    Mayo Clinic Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Neurology 68:301-3. 2007
    Pathologic gambling is an impulse control disorder previously reported to complicate dopamine agonist therapy in patients with Parkinson disease. It has not been described in association with dopamine agonist therapy of other conditions...
  82. pmc Excessive discounting of delayed reinforcers as a trans-disease process contributing to addiction and other disease-related vulnerabilities: emerging evidence
    Warren K Bickel
    Addiction Recovery Research Center, Virginia Tech Carilion Research Institute, Roanoke, VA 24016, USA
    Pharmacol Ther 134:287-97. 2012
    ..discounting rates have been observed in individuals with other behavioral maladies such as pathological gambling, poor health behavior, and overeating...
  83. ncbi Randomness and inductions from streaks: "gambler's fallacy" versus "hot hand"
    Bruce D Burns
    Department of Psychology, Michigan State University, East Lansing, Michigan 48824 1117, USA
    Psychon Bull Rev 11:179-84. 2004
    ..A manipulation check confirmed our assumptions about the scenarios. We found that with less random scenarios, the participants were more likely to continue a streak...
  84. ncbi Post-decision wagering objectively measures awareness
    Navindra Persaud
    Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
    Nat Neurosci 10:257-61. 2007
    ..participants fail to maximize cash earnings by wagering high following correct decisions in blindsight, the Iowa gambling task and an artificial grammar task...
  85. ncbi Psychosocial stress and its relationship to gambling urges in individuals with pathological gambling
    Igor Elman
    Clinical Psychopathology Laboratory, McLean Hospital and Harvard Medical School, Belmont, Massachusetts 02478 9106, USA
    Am J Addict 19:332-9. 2010
    We sought to explore a potential link between psychosocial stress exposure and pathological gambling (PG). Patients with PG displayed significantly higher scores on the daily stress inventory (DSI) than did healthy subjects...
  86. ncbi Sex differences in subclinical and DSM-IV pathological gambling: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Carlos Blanco
    Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 36:943-53. 2006
    To examine sex differences in DSM-IV subclinical and pathological gambling in nationally representative data of the US population.
  87. pmc An fMRI study of risk-taking following wins and losses: implications for the gambler's fallacy
    Gui Xue
    Department of Psychology, University of Southern California, Los Angeles, California 90089 1061, USA
    Hum Brain Mapp 32:271-81. 2011
    ..This has significant implications for our understanding of the gambler's fallacy and human decision making under risk...
  88. ncbi Trait anxiety affects decision-making differently in healthy men and women: towards gender-specific endophenotypes of anxiety
    L de Visser
    Department of Animals in Science and Society, Utrecht University, Utrecht, The Netherlands Rudolf Magnus Institute of Neuroscience, UMC Utrecht, The Netherlands
    Neuropsychologia 48:1598-606. 2010
    ..trait anxiety, measured by the State-Trait Anxiety Inventory, and complex decision-making, measured by the Iowa Gambling Task, in healthy male and female volunteers...
  89. pmc Brain maps of Iowa gambling task
    Ching Hung Lin
    Institute of Neuroscience, School of Life Science, National Yang Ming University, Taipei, Taiwan
    BMC Neurosci 9:72. 2008
    ..The Iowa gambling task (IGT) was designed to verify the SMH...
  90. ncbi The effect of reward magnitude differences on choosing disadvantageous decks in the Iowa Gambling Task
    Ruud van den Bos
    Ethology and Welfare, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 2, NL 3584 CM Utrecht, The Netherlands
    Biol Psychol 71:155-61. 2006
    In the Iowa Gambling Task, participants have to develop a long-term profitable monetary scenario in a situation of uncertainty and a conflict between the chance of encountering an immediate large reward (100 US dollars) in two long-term ..
  91. pmc Perceiving an opponent's loss: gender-related differences in the medial-frontal negativity
    Hirokata Fukushima
    Department of General Systems Studies, Graduate School of Arts and Sciences, The University of Tokyo, 3 8 1 Komaba, Meguro ku, Tokyo 153 8902, Japan
    Soc Cogn Affect Neurosci 1:149-57. 2006
    ..perceptions to one's own and another's monetary gain or loss, while individuals played a 'competitive' two-person gambling game, in which one's monetary gain resulted in the other's loss...
  92. ncbi Factors associated with dopaminergic drug-related pathological gambling in Parkinson disease
    Valerie Voon
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Arch Neurol 64:212-6. 2007
    To evaluate factors associated with pathological gambling (PG) in Parkinson disease (PD).
  93. ncbi Risk-prone individuals prefer the wrong options on a rat version of the Iowa Gambling Task
    Marion Rivalan
    CNRS UMR 5227, Universite Victor Segalen Bordeaux 2, Bordeaux Cedex, France
    Biol Psychiatry 66:743-9. 2009
    Decision making in complex and conflicting situations, as measured in the widely used Iowa Gambling Task (IGT), can be profoundly impaired in psychiatric disorders, such as attention-deficit/hyperactivity disorder, drug addiction, and ..
  94. ncbi A double-blind placebo-controlled study of the efficacy and safety of paroxetine in the treatment of pathological gambling
    Suck Won Kim
    Department of Psychiatry, University of Minnesota, Minneapolis, USA
    J Clin Psychiatry 63:501-7. 2002
    This randomized, double-blind, placebo-controlled study investigated the efficacy and tolerability of paroxetine in the treatment of pathological gambling.
  95. ncbi Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 69:433-40. 2008
    Pathological gambling is associated with bipolar disorder and dopamine dysfunction. Olanzapine is a second-generation antipsychotic with mood-stabilizing properties and antagonistic activity at several dopamine receptors...
  96. ncbi Pathological gambling in Parkinson disease is reduced by amantadine
    Astrid Thomas
    Department of Neurology, University G D Annunzio, Chieti and Pescara, Italy
    Ann Neurol 68:400-4. 2010
    To investigate the possible efficacy of amantadine in the control of pathological gambling (PG) associated with Parkinson disease (PD), 17 PD patients with PG were randomly selected for a double-blind crossover study with amantadine 200mg/..
  97. ncbi A pilot placebo-controlled study of fluvoxamine for pathological gambling
    Carlos Blanco
    Department of Psychiatry, Columbia University, New York, New York, USA
    Ann Clin Psychiatry 14:9-15. 2002
    The objective of this study was to evaluate the efficacy of fluvoxamine in the treatment of pathological gambling. Thirty-two patients were treated for 6 months in a double-blind, placebo-controlled study of fluvoxamine 200 mg/day...
  98. ncbi Cue-induced brain activity in pathological gamblers
    David N Crockford
    University of Calgary, Alberta, Canada
    Biol Psychiatry 58:787-95. 2005
    ..magnetic resonance imaging (fMRI) have identified differential brain activity in healthy subjects performing gambling tasks and in pathological gambling (PG) subjects when exposed to motivational and emotional predecessors for ..
  99. ncbi Gambling disorders
    David C Hodgins
    Department of Psychology, University of Calgary, Calgary, AB, Canada
    Lancet 378:1874-84. 2011
    b>Gambling disorders, including pathological gambling and problem gambling, have received increased attention from clinicians and researchers over the past three decades since gambling opportunities have expanded around the world...
  100. pmc Brain activation patterns associated with cue reactivity and craving in abstinent problem gamblers, heavy smokers and healthy controls: an fMRI study
    Anna E Goudriaan
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, The Netherlands
    Addict Biol 15:491-503. 2010
    ..A functional magnetic resonance imaging event-related cue reactivity paradigm, consisting of gambling, smoking-related and neutral pictures, was employed in 17 treatment-seeking non-smoking PRG, 18 non-gambling HSM, ..
  101. ncbi Dopamine receptor D4 polymorphism predicts the effect of L-DOPA on gambling behavior
    Christoph Eisenegger
    Institute for Empirical Research in Economics, University of Zurich, Zurich, Switzerland
    Biol Psychiatry 67:702-6. 2010
    ..patients who are treated with dopaminergic drugs develop certain behavioral addictions such as pathological gambling. The fact that only a subgroup of these patients develops pathological gambling suggests an interaction between ..

Research Grants69

  1. Neural Substrates of Goal-Directed Learning in the Human Brain
    JOHN O DOHERTY; Fiscal Year: 2007
    ..to change using "willpower", as is the case in obsessive compulsive disorders, eating disorders, compulsive gambling and drug addiction...
  2. Early social stress, novelty seeking, and impulsive behavior
    David M Lyons; Fiscal Year: 2013
    ..Novelty seeking can be costly, however, as it increases the prevalence of reckless driving, pathological gambling, unprotected sex, under-age drinking, and other forms of alcohol and drug abuse...
  3. Uncertainty and stimulant self-administration
    PAUL R VEZINA; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pathological gambling and drug addiction may share common neuronal substrates...
  4. A Follow-up Study of Addictions and Co-Occurring Disorders in Older Adults
    Donald W Black; Fiscal Year: 2013
    ..this application is to conduct a controlled, blind longitudinal follow-up (f/u) of older adults with pathological gambling (PG). This study will be the first of its type and set the standard...
  5. N-Acetyl Cysteine plus Behavioral Therapy for Nicotine Dependent Pathological Gam
    Jon E Grant; Fiscal Year: 2010
    ..Pathological gambling (PG), a serious public health problem with detrimental effects on individuals and families, and with an estimated ..
  6. A novel rodent model of dopamine agonist-induced impulsive control disorders
    T Celeste Napier; Fiscal Year: 2012
    ..A significant subset of these patients treated with DA agonists develop impulse control disorders (ICDs) such as gambling disorders, compulsive sexual behavior, compulsive buying, and binge-eating...
  7. Role of D3 receptors in drug-induced impulsivity in a rat model of Parkinson's di
    STEPHANIE E TEDFORD; Fiscal Year: 2013
    ..g., 13.6%1) develop ICDs, i.e., behavioral addictions like pathological gambling, hypersexuality, compulsive shopping and binge eating...
  8. Dopamine Effects on Mesocorticolimbic Function in Parkinson Disease
    DANIEL OLIVER CLAASSEN; Fiscal Year: 2013
    ..are characterized by an increased and compulsive participation in certain behaviors, such as sex, eating, gambling, shopping, and hobbies. DAA use, more so than Levodopa, is associated with this disorder...
  9. Poverty, Stress, and Discounting: A potential micro-mechanism for behavior change
    Johannes Haushofer; Fiscal Year: 2013
    Project Summary Persons affected by conditions as diverse as Attention Deficit Hyperactivity Disorder, compulsive gambling behavior, nicotine addiction, and alcoholism share a common trait: abnormally high impulsivity...
  10. INHIBITORY DEFICITS IN HUMAN AND ANIMAL MODELS OF BIPOLAR DISORDER
    William Perry; Fiscal Year: 2013
    ..exploration, the Conner's Continuous Performance Test to assess attentional inhibition, the Iowa Gambling Task to assess risk-taking inhibition, and the Wisconsin Card Sorting Task to assess perseverative inhibition...
  11. 2/2 Gambling Addiction: Treatment Mediators and Moderators
    Carlos Blanco; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Pathological gambling is a highly underrated, yet extremely serious public health problem with enormously detrimental effects on individuals and families, and with an estimated yearly cost to society ..
  12. Predictors of Pathological Gambling among African-American Young Adults
    Silvia Saboia Martins; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Little is known about gambling and problem/pathological gambling among minority populations in the U.S...
  13. Timing, reward processing and choice
    Kimberly Kirkpatrick; Fiscal Year: 2013
    ..differences in discounting rates including Attention Deficit/Hyperactivity Disorder (AHDH), drug addiction, and gambling. Impulsive individuals are less able to wait for outcomes and thus show a bias to choose shorter-delayed options ..
  14. Neural Mechanisms of Risk Preference Following Adolescent Alcohol Exposure
    Jeremy J Clark; Fiscal Year: 2013
    ..e. a "gambling buzz")...
  15. Dopamine D2/D3 Receptors in Compulsive Disorders
    James H Woods; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Compulsive behaviors, including excessive eating, gambling, shopping, exercising, or drug-taking, can develop over time in individuals without other psychopathology...
  16. Neurodevelopmental Correlates of Reward Processing and Adolescent Substance Abuse
    JAMIE HANSON; Fiscal Year: 2012
    ..A modified gambling task will also be used to behaviorally probe decision-making in at-risk adolescents...
  17. Modulators of maladaptive decision-making in methamphetamine dependence
    Milky Kohno; Fiscal Year: 2013
    ..When performing gambling tasks, methamphetamine-dependent individuals exhibit greater risk-taking than healthy control subjects in order ..
  18. Problem Gambling - A Decade of Change
    John W Welte; Fiscal Year: 2012
    Project Summary/Abstract The last decade has seen rapid growth in the public profile and availability of gambling in the U.S. The laws regulating gambling have been liberalized, and public approval of gambling may have grown...
  19. NEUROPHYSIOLOGY IN CHILDREN AT HIGH RISK FOR ALCOHOLISM
    Bernice Porjesz; Fiscal Year: 2013
    ..To complement electrophysiological studies, structural/functional (fMRI) imaging using the same Go/NoGo and gambling tasks will be implemented to understand the (frontal) circuits and localize network impairments that are ..
  20. Development & validation of an implicit measure of alcohol-related self-identity
    DEBI A contact LAPLANTE; Fiscal Year: 2010
    ..e., to drugs and gambling) and the settings in which these measures will be tested (i.e., to clinical settings)...
  21. RCT OF WEB VS. IN-PERSON SUD AND COMORBIDITY TREATMENT
    Mary E Larimer; Fiscal Year: 2013
    ..by applicant): The broad, long-term objective of the current research is to reduce the prevalence of disordered gambling and co-morbid substance use disorders and related harm in the population, through development of efficacious and ..
  22. Large Scale Natural Experiment of Community Economic Development: Effects on Vio
    Anthony Fabio; Fiscal Year: 2013
    ..In the second neighborhood, the North Side, gambling has been legalized, a casino is being built, and the casino is scheduled to open May 2009...
  23. Cognitive and Affective Mechanisms of Risk for Suicidal Thoughts and Behaviors
    David B Goldston; Fiscal Year: 2013
    ..bias characterized by greater focus on immediate rewards rather than delayed consequences, assessed with the Iowa Gambling Task), and (b) implicit affect (assessed with the Affect Misattribution Procedure), (c) eye blink startle reflex (..
  24. Decision Making and Orbitofrontal Cortex
    Daeyeol Lee; Fiscal Year: 2013
    ..the neurons in the orbitofrontal cortex will integrate multiple reward parameters during an inter-temporal gambling task in which the magnitude, delay, and uncertainty of reward available from each option is systematically ..
  25. Ecological &Sociocultural Influences on Native American Gambling &Alcohol Use
    Grace M Barnes; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Despite a marked increase in the availability of gambling opportunities on Native American lands and in surrounding geographic areas, there is a lack of research examining the effects of gambling ..
  26. Serotonin 1B Receptor Imaging in Pathological Gambling and Alcohol Dependence
    Alexander Neumeister; Fiscal Year: 2010
    ..understand the addiction process, we propose to study patients with alcohol dependence (AD) and pathological gambling (PG) and compare serotonin (5-HT), type 1B (5-HT1B) receptor expression as determined with positron emission ..
  27. Bupropion for ADHD in Adolescents with Substance Use Disorders
    PAULA DEGRAFFENREID RIGGS; Fiscal Year: 2012
    ..g., methamphetamine dependence, pathological gambling)...
  28. Behavioral Economics in a Laboratory-Based Token Economy
    Timothy D Hackenberg; Fiscal Year: 2013
    ..also been fruitfully applied in recent years to a wide range of health- related problems, including addictions, gambling, and obesity, to name just a few. Behavioral economics is thus of practical as well as theoretical importance...
  29. Information throughput in risky decision making underlying self-regulation
    John M Hinson; Fiscal Year: 2012
    ..cognitive information and determine the impact on frame-induced decision making in the newly developed Framed Gambling Task, which allows better analysis of risk and ambiguity, also with challenges to hot and cold cognition...
  30. 41st-45th Annual International Narcotics Research Conferences
    Lakshmi A Devi; Fiscal Year: 2013
    ..novel opioid ligands, epigenetics of opioid peptides and receptors, opioids in neuropathic pain, alcohol &gambling addictions and opioid-cannabinoid interactions...
  31. Risk-Taking Following Trauma Cue Exposure in Substance Users with PTSD
    Matthew T Tull; Fiscal Year: 2012
    ..2002) and the Iowa Gambling Task (Bechara et al., 1994). We will examine the effect of trauma cue exposure (vs...
  32. BRAIN DYSFUNCTION AND ALCOHOLISM
    Bernice Porjesz; Fiscal Year: 2012
    ..deficits, we propose to implement structural/functional (fMRI) imaging methods during Go/No-Go and gambling tasks and will attempt to understand the frontal circuits and localize network disruptions that are associated ..
  33. Impulsivity In Pathological Gambling
    Timothy W Fong; Fiscal Year: 2010
    ..Timothy W. Fong to conduct patient-oriented research in pathological gambling. Drs...
  34. Control Your Cravings: A Web-Based Transdiagnostic Self-Management Program
    LINDA SUE RUEHLMAN; Fiscal Year: 2012
    ..a critical component of treatment for self- regulatory problems such as substance and alcohol abuse, overeating, gambling, smoking, or impulsive sexual behavior...
  35. Bridging Efficacy and Effectiveness in Drug Abuse Treatment
    Carlos Blanco; Fiscal Year: 2012
    ..The goal of second project, "Treatment for Adolescents with Pathological Gambling" funded by the New York State Office of Alcohol and Substance Abuse Services, is the development of a manualized ..
  36. Understanding Alcohol Use Over Time in Early Mid-Adulthood for At-Risk Men
    Deborah M Capaldi; Fiscal Year: 2013
    ..morbid substance use (tobacco, marijuana, other illicit drugs, non-prescription and over-the-counter drugs), and gambling behavior. In addition, prediction models of treatment seeking will be examined...
  37. Neural mechanisms of risky behavior avoidance
    Joshua W Brown; Fiscal Year: 2010
    ..The specific aims of this project are twofold and will use methods of stop-signal, gambling and task-switching behavioral tasks, individual trait difference measures, and fMRI in healthy individuals...
  38. Early onset vs. pre-existing vulnerabilities in adolescent drug use
    Daniel Romer; Fiscal Year: 2013
    ..Finally, it can determine whether other adverse outcomes apart from drug use are traceable to early weakness in WMA, such as problem gambling, anti-social behavior, sexual risks, and poor academic performance (Aim 3).
  39. Neural mechanism of preference formation during risky decisions
    Timothy J Pleskac; Fiscal Year: 2013
    ..Experimentally, we create a novel gambling task called the flash gambling task (FGT) in which participants choose between a sure payoff and a lottery that ..
  40. Frontal Striatal Activity During Decision Making in Substance Abuse
    Jody Tanabe; Fiscal Year: 2009
    ..decision making administered to substance dependent individuals (SDI) and other patient populations is the Iowa Gambling Task (IGT) (Bechara et al., 1994)...
  41. Neural Correlates of Avoidance Learning in Substance Abuse
    Jody L Tanabe; Fiscal Year: 2013
    ..This will be accomplished using functional MRI (fMRI) and a reinforcement learning paradigm based on the Iowa Gambling Task...
  42. Transcranial Direct Current Stimulation for Cognitive Enhancement in FASD
    BRIAN COFFMAN; Fiscal Year: 2013
    ..risky decision making will first be determined using the sustained attention to response task and the Cambridge gambling task, respectively. Behavioral and EEG data will be used as a metric for the effectiveness of tDCS...
  43. Experimental Manipulations of Impulsivity: Effects on Gambling and Drug Taking
    Gregory J Madden; Fiscal Year: 2013
    ..e., extreme devaluation of delayed outcomes) is correlated with addictive disorders such as pathological gambling and substance abuse...
  44. An Internet application for SMART Recovery
    REID KEVIN HESTER; Fiscal Year: 2012
    ..OA program is to help users learn cognitive and behavioral skills to abstain from drinking, drug use, and problem gambling. The major project goals in Phase II are to complete the development of the OA web application and evaluate the ..
  45. SEROTONIN/NOREPINEPHRINE FUNCTION--PATHOLOGICAL GAMBLING
    Eric Hollander; Fiscal Year: 2000
    ..Pathological gambling (PG) is a chronic, disabling, and understudied impulse control disorder which affects 1-3% of the population...
  46. The Neuronal Mechanisms Underlying Choice Behavior in the Frontal Lobe
    Steve Kennerley; Fiscal Year: 2009
    ..hyperactivity disorder (ADHD), pathological aggression, phobic and anxiety disorder, addiction and compulsive gambling. In severe cases, removal of the ACC has even been used as a treatment for pathological aggression, anxiety ..
  47. Emotion-Based Decision Making in Children with Fetal Alcohol Spectrum Disorders
    LINNEA ELIZABETH VAURIO; Fiscal Year: 2010
    ..The Iowa Gambling Task (IGT) is a widely used measure of decision making, simulating unpredictable reward and punishment ..
  48. The Influence of Emotion Regulation on the Neural Systems of Reward Processing
    Mauricio Delgado; Fiscal Year: 2007
    ..DESCRIPTION (provided by applicant): Risk-taking and reward-seeking behaviors are staples of compulsive gambling, a progressive addiction that affects many aspects of life...
  49. Impulse Control Disorders in Parkinson's Disease Conference
    Mark Stacy; Fiscal Year: 2007
    ..While the compulsive gambling, purchasing, shopping; binge eating; compulsive engagement in hobbies, and punding behaviors are increasingly ..
  50. Inhibitory Control: Toward a Vulnerability Phenotype
    FRANCES GABBAY; Fiscal Year: 2007
    ..In each session, subjective effects will be assessed before and after capsule administration, and a gambling task will be administered at the end of the session...
  51. AUTONOMIC AROUSAL AND DECISION MAKING IN HUNTINGTON'S
    Julie Stout; Fiscal Year: 2000
    In a recent reports using a simulated gambling task, Bechara, Damasio, and their colleagues propose that in a risky decision making context, people employ somatic guidance to facilitate selection of advantageous response alternatives...
  52. Self-Regulation in Co-Occurring TBI and Substance Abuse
    Jennifer Bogner; Fiscal Year: 2006
    ..Bechara's Gambling Task may provide the ideal analog for studying self-regulation and sensitivity to contingencies in persons with ..
  53. PATHOLOGICAL GAMBLING--COURSES, CONSEQUENCES, AND CAUSES
    Seth Eisen; Fiscal Year: 2004
    The broad goals of this proposal are to examine the courses, consequences, and causes of problem and pathological gambling (P&PG) in a sample of 1,200 middle-aged male-male monozygotic and dizygotic twin pair members (2,400 ..
  54. Serotonin impulsivity and health-risk behavior
    Parthasarathi Nag; Fiscal Year: 2007
    ..to which serotonin system genotypes, exposure to early-life stress and gender are associated with HRB, such as gambling, disordered eating, substance use, risky sex, and risky driving, and how impulsivity may mediate these relations...
  55. Behavioral and neuroscience studies of risk taking and perceived control
    ADAM GOODIE; Fiscal Year: 2007
    ..time, the illusion of control has become a prominent explanatory construct in the investigation of pathological gambling. Using recent methodological developments, which include advances in modeling decision weights with techniques ..
  56. Drug Abuse, Social Decision-Making, and Sex-Related Functional Brain Asymmetry
    DANIEL T TRANEL; Fiscal Year: 2010
    ..of the VMPC in regard to social decision- making, using tasks such as the Ultimatum Game, Trust Game, Iowa Gambling Task, and Ellsberg Tasks; (2) To extend the investigation of sex-related functional asymmetry to other brain ..
  57. PSYCHIATRIC EPIDEMIOLOGY AND BIOSTATISTICS
    Linda Cottler; Fiscal Year: 2007
    ..such as mood and substance use disorders, schizophrenia, PTSD, Alzheimer's, child disorders, pathological gambling, personality disorders, and eating disorders, applicants have a wide range of opportunities for research training ..
  58. DISCOUNTING MODELS OF IMPULSIVENESS AND SELF CONTROL
    KRIS KIRBY; Fiscal Year: 2000
    ..have been associated with more serious problems, such as substance abuse, eating disorders, and pathological gambling. The principal investigator and colleagues have developed two methodologies for assessing individual differences ..
  59. An image-guided neurosurgical workstation
    Paul Glimcher; Fiscal Year: 2007
    ..such as cortical prostheses to help paralyzed patients, and understand disorders such as compulsive behavior and gambling. The instrument will be incorporated into the existing animal surgical facility at NYU and guide implantation of ..
  60. Cognitive-Behavioral Therapy for Pathological Gambling
    Jon Grant; Fiscal Year: 2008
    DESCRIPTION (provided by candidate): Pathological gambling is a relatively common disorder characterized by persistent and recurrent maladaptive patterns of gambling behavior...
  61. Web-Based Prevention for At-Risk Gamblers
    TY LOSTUTTER; Fiscal Year: 2009
    Disordered gambling effects millions of Americans and is associated with higher rates of depression, anxiety, suicide attempts/completions, work/academic failure, criminal activity, family/relationship disruptions, comorbid substance use/..
  62. Social Cognition and Human Orbital Prefrontal Cortex
    Robert Knight; Fiscal Year: 2004
    ..Risky decision making will be assessed using the Perceptions of Risk Questionnaire and a roulette gambling task...
  63. PREVALENCE OF GAMBLING PROBLEMS AMONG METHADONE PATIENTS
    Barry Spunt; Fiscal Year: 1993
    Pathological gambling is recognized to be a disorder of impulse control...
  64. Toward an Animal Model of Gambling: The Economics of Risky Choice
    CARLA LAGORIO; Fiscal Year: 2009
    Pathological gambling is recurrent maladaptive gambling behavior that persists despite harmful negative consequences or a desire to stop...
  65. DEVELOPMENT OF THE GAMBLING PRACTICES SCALE
    Linda Ruehlman; Fiscal Year: 2001
    The long-term goal of the proposed project is the development of the Gambling Practices Scale (GAMPS), a self-report instrument designed to identify maladaptive gambling practices...
  66. OPERANT ANALYSIS OF CHOICE AND SELF CONTROL
    Howard Rachlin; Fiscal Year: 2000
    ..Because much dysfunctional human behavior, including compulsive gambling, smoking, overeating, alcoholism, drug abuse, and unsafe sexual practice, may be seen as failure of self control, ..
  67. TREATMENT FOR DUALLY DEPENDENT METHADONE PATIENTS
    Nancy Petry; Fiscal Year: 2002
    ....
  68. ENHANCING THE ASI WITH GAMBLING & ADHD DOMAINS
    LESLIE CHERNEN; Fiscal Year: 2000
    ..status domains: Attention Deficit Hyperactivity Disorder (ADHD) and the screening/assessment of problem gambling. The Adult Behavior Rating Scale (for ADHD), the South Oaks Gambling Screen and a gambling pathology subdomain ..