psychomotor disorders

Summary

Summary: Abnormalities of motor function that are associated with organic and non-organic cognitive disorders.

Top Publications

  1. ncbi Psychomotor disadaptation syndrome. A new clinical entity in geriatric patients
    France Mourey
    Centre Hospitalier Regional et Universite de Dijon, France
    Geriatrics 59:20-4. 2004
  2. ncbi Disabilities in children with hydrocephalus--a population-based study of children aged between four and twelve years
    E K Persson
    Department of Paediatrics, County Hospital, Halmstad, Sweden
    Neuropediatrics 37:330-6. 2006
  3. ncbi Neo-striatal rCBF correlates of psychomotor slowing in patients with major depression
    I Hickie
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychiatry Res 92:75-81. 1999
  4. ncbi Ocular motor differences between melancholic and non-melancholic depression
    C Winograd-Gurvich
    Experimental Neuropsychology Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Melbourne 3800, Australia
    J Affect Disord 93:193-203. 2006
  5. ncbi [Psychomotor retardation associated to depression differs from that of normal aging]
    Sylvie Bonin-Guillaume
    Service de médecine interne gériatrie, Assistance Publique de Marseille, Hopital Nord, Marseille, France
    Psychol Neuropsychiatr Vieil 6:137-44. 2008
  6. ncbi Frontal white matter integrity is related to psychomotor retardation in major depression
    Sebastian Walther
    University Hospital of Psychiatry, University of Bern, Bolligenstrasse 111, 3000 Bern 60, Switzerland
    Neurobiol Dis 47:13-9. 2012
  7. ncbi Caudate nucleus volumes and genetic determinants of homocysteine metabolism in the prediction of psychomotor speed in older persons with depression
    Sharon Naismith
    School of Psychiatry, University of New South Wales, PO Box 1, Rozelle NSW 2039, Sydney, Australia
    Am J Psychiatry 159:2096-8. 2002
  8. ncbi Characterizing major depression phenotypes by presence and type of psychomotor disturbance in adolescents and young adults
    Adam M Leventhal
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island 02912, USA
    Depress Anxiety 25:575-92. 2008
  9. ncbi Effect of apomorphine on motor and cognitive function in melancholic patients: a preliminary report
    M P Austin
    Mood Disorders Unit, Prince of Wales Hospital and School of Psychiatry, University of New South Wales, Sydney, 2031, Australia
    Psychiatry Res 97:207-15. 2000
  10. ncbi Experimental evidence for a motivational origin of cognitive impairment in major depression
    A Scheurich
    Department of Psychiatry, University of Mainz, Mainz, Germany
    Psychol Med 38:237-46. 2008

Detail Information

Publications223 found, 100 shown here

  1. ncbi Psychomotor disadaptation syndrome. A new clinical entity in geriatric patients
    France Mourey
    Centre Hospitalier Regional et Universite de Dijon, France
    Geriatrics 59:20-4. 2004
    ..In addition to medical and neurological evaluations, a specific rehabilitation program is one of the most important aspects of the management of patients showing PDS...
  2. ncbi Disabilities in children with hydrocephalus--a population-based study of children aged between four and twelve years
    E K Persson
    Department of Paediatrics, County Hospital, Halmstad, Sweden
    Neuropediatrics 37:330-6. 2006
    ..Children with hydrocephalus represent a heterogeneous group with various aetiologies and disability profiles. Over the years, continuous changes in medical care have occurred and updated information is important...
  3. ncbi Neo-striatal rCBF correlates of psychomotor slowing in patients with major depression
    I Hickie
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychiatry Res 92:75-81. 1999
    ..Such rCBF findings may implicate the neo-striatum in the neurobiology of major depression...
  4. ncbi Ocular motor differences between melancholic and non-melancholic depression
    C Winograd-Gurvich
    Experimental Neuropsychology Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Melbourne 3800, Australia
    J Affect Disord 93:193-203. 2006
    ..Eye movement studies in depression are infrequent and findings are inconclusive...
  5. ncbi [Psychomotor retardation associated to depression differs from that of normal aging]
    Sylvie Bonin-Guillaume
    Service de médecine interne gériatrie, Assistance Publique de Marseille, Hopital Nord, Marseille, France
    Psychol Neuropsychiatr Vieil 6:137-44. 2008
    ..These results clearly show that PMR in geriatric depression differed from the age related slowing. Depression also spares stimulus preprocessing in old individuals as it did in younger adults...
  6. ncbi Frontal white matter integrity is related to psychomotor retardation in major depression
    Sebastian Walther
    University Hospital of Psychiatry, University of Bern, Bolligenstrasse 111, 3000 Bern 60, Switzerland
    Neurobiol Dis 47:13-9. 2012
    ..Therefore, signs of psychomotor slowing in major depressive disorder may be linked to changes of the white matter integrity of the motor system...
  7. ncbi Caudate nucleus volumes and genetic determinants of homocysteine metabolism in the prediction of psychomotor speed in older persons with depression
    Sharon Naismith
    School of Psychiatry, University of New South Wales, PO Box 1, Rozelle NSW 2039, Sydney, Australia
    Am J Psychiatry 159:2096-8. 2002
    ..The authors sought to determine whether caudate nucleus volumes or specific genotypes predict psychomotor slowing in older persons with depression...
  8. ncbi Characterizing major depression phenotypes by presence and type of psychomotor disturbance in adolescents and young adults
    Adam M Leventhal
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island 02912, USA
    Depress Anxiety 25:575-92. 2008
    ..Retarded depression evidenced little stability or heritability. These findings offer partial support of the phenotypic status of agitated and agitated-retarded depression in youths...
  9. ncbi Effect of apomorphine on motor and cognitive function in melancholic patients: a preliminary report
    M P Austin
    Mood Disorders Unit, Prince of Wales Hospital and School of Psychiatry, University of New South Wales, Sydney, 2031, Australia
    Psychiatry Res 97:207-15. 2000
    ..Our conclusions, however, were limited by small sample size; minimal baseline task impairment in depressed compared to control subjects; mild sedation in many subjects during task performance; and lack of serum apomorphine levels...
  10. ncbi Experimental evidence for a motivational origin of cognitive impairment in major depression
    A Scheurich
    Department of Psychiatry, University of Mainz, Mainz, Germany
    Psychol Med 38:237-46. 2008
    ..Diagnostic criteria and empirical evidence support the existence of cognitive deficits in depression. However, depressed mood, loss of interest and low self-efficacy might influence cognitive performance...
  11. ncbi Motor and cognitive aspects of motor retardation in depression
    M P Caligiuri
    Department of Psychiatry 0603, Movement Disorders Laboratory, University of California at San Diego, La Jolla, CA 92093, USA
    J Affect Disord 57:83-93. 2000
    ..However, overt presentations of motor slowing cannot distinguish slowness due to cognitive factors from slowness due to neuromotor disturbances...
  12. ncbi Psychomotor retardation correlates with frontal hypoperfusion and the Modified Stroop Test in patients under 60-years-old with major depression
    Hiroyuki Narita
    Department of Psychiatry, Yokohama City University School of Medicine, Yokohama, Japan
    Psychiatry Clin Neurosci 58:389-95. 2004
    ..The present findings suggest that frontal hypoperfusion, frontal dysfunction, and psychomotor retardation were associated with one another in not only the old but also the young patients with depression...
  13. ncbi Psychomotor changes in melancholic and atypical depression: unipolar and bipolar-II subtypes
    Franco Benazzi
    Department of Psychiatry, National Health Service, and Outpatient Psychiatry Private Center, Forli, Italy
    Psychiatry Res 112:211-20. 2002
    ..5 vs. 0.0%). Logistic regression controlling for age, gender and illness duration had little effect on the findings, which suggests that psychomotor changes are not core features of melancholic MDE...
  14. ncbi Validation of the Retardation Rating Scale for detecting depression in geriatric inpatients
    Sylvie Bonin-Guillaume
    Service de médecine interne et gériatrie, Assistance Publique des Hopitaux de Marseille, Hopital Nord, 13915 Marseille Cedex 20, France
    Int J Geriatr Psychiatry 22:68-76. 2007
    ..Validation in the elderly of the Retardation Rating Scale (RRS), which includes items related to motor and mental retardation but not vegetative items, and may be particularly well-suited for the diagnosis of depression in the elderly...
  15. ncbi Objective assessment of psychomotor retardation in primary care patients with depression
    Grant L Iverson
    Department of Psychiatry, University of British Columbia and HeartLink Canada, Inc, Vancouver, Canada
    J Behav Med 27:31-7. 2004
    ..Patients with low activity levels were 6.0 times more likely to fall in the severely depressed group than patients with more normal activity levels...
  16. ncbi Kinematical analysis of handwriting movements in depressed patients
    R Mergl
    Laboratory of Clinical Neurophysiology, Department of Psychiatry, Ludwig Maximilians Universitat Munchen, Munchen, Germany
    Acta Psychiatr Scand 109:383-91. 2004
    ..We hypothesized that depressed patients draw and write significantly slower than controls and that motor disturbances become more pronounced under bi-manual demands...
  17. ncbi Bipolar II vs. unipolar depression: psychopathologic differentiation by dimensional measures
    Elie G Hantouche
    Adult Psychiatry, Mood Center, Psychiatry Department, Pitié Salpêtrière Hôpital, 47 bd de l Hopital, 75013 Paris, France
    J Affect Disord 84:127-32. 2005
    ..UP MDD in a large national sample...
  18. ncbi Psychomotor retardation in elderly depressed patients
    M P B I Pier
    Department of Psychiatry, University Medical Centre, Reinier Postlaan 10, Nijmegen 6525 GC, The Netherlands
    J Affect Disord 81:73-7. 2004
    ..The purpose of this study was (1) to try and establish whether elderly depressed patients show PR, and (2) if so, which process (cognitive/motor or both) is mainly slowed?..
  19. ncbi Physical components of depression and psychomotor retardation
    Yves Lecrubier
    Hopital La Salpetriere, INSERM, Paris, France
    J Clin Psychiatry 67:23-6. 2006
    ..In addition, data have indicated significantly improved psychomotor retardation in patients with depression after 3 months of treatment...
  20. ncbi Inter-rater reliability of the French version of the core index for melancholia
    J Thuile
    Service de Psychiatrie, Clinique des maladies mentales et de l Encéphale, Centre Hospitalier Sainte Anne, université Paris V René Descartes, 100 rue de la Santé, 75674 Paris Cedex 14, France
    J Affect Disord 88:193-208. 2005
    ..We report an inter-rater reliability study of the French version of the CORE...
  21. ncbi Endogenous cannabinoid signaling and psychomotor disorders
    A Giuffrida
    Department of Pharmacology, University of California, 360 Med Surge II, Irvine, CA, USA
    Prostaglandins Other Lipid Mediat 61:63-70. 2000
    ..This mini-review discusses the participation of the endogenous cannabinoid system in the regulation of motor behaviors, pointing out its possible involvement in the pathophysiology of psychomotor disorders.
  22. ncbi Is the diagnosis of melancholia important in shaping clinical management?
    Gordon Parker
    School of Psychiatry, University of New South Wales, Australia bBlack Dog Institute, Sydney, NSW, Australia
    Curr Opin Psychiatry 20:197-201; discussion 202-3. 2007
  23. ncbi Psychomotor symptoms in depression: a diagnostic, pathophysiological and therapeutic tool
    Didier Schrijvers
    Collaborative Antwerp Psychiatric Research Institute, University of Antwerp, Universiteitsplein 1 B 2610 Antwerp, Belgium
    J Affect Disord 109:1-20. 2008
    ..In the current review of the recent literature, we aim to argue the importance of psychomotor symptoms in depression and propose directions for future research...
  24. ncbi A comparative study of milnacipran and paroxetine in outpatients with major depression
    Daniel Sechter
    Service de psychiatrie de l adulte, Centre Hospitalier Universitaire St Jacques, Besancon, Cedex F 25030, France
    J Affect Disord 83:233-6. 2004
    ..Milnacipran is a dual-action antidepressant which inhibits both serotonin and noradrenaline reuptake with no affinity for any neurotransmitter receptor studied...
  25. ncbi Differential patterns of psychomotor functioning in unmedicated melancholic and nonmelancholic depressed patients
    M P B I Pier
    Department of Psychiatry, University Medical Center, University of Nijmegen, Reinier Postlaan 10, Nijmegen 6525 GC, The Netherlands
    J Psychiatr Res 38:425-35. 2004
    ..Differences in psychomotor functioning between melancholic and nonmelancholic depressed patients could imply different underlying neurobiological disturbances in these subtypes of major depression...
  26. ncbi Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review
    Sergiy Konovalov
    Department of Psychiatry, Yale University School of Medicine, New Haven, U S A
    Int Psychogeriatr 20:293-308. 2008
    ....
  27. ncbi Vagal regulation of heart rate in the prediction of developmental outcome for very low birth weight preterm infants
    J A Doussard-Roosevelt
    Institute for Child Study, University of Maryland, College Park, 20742 1131, USA
    Child Dev 68:173-86. 1997
    ..The findings directly respond to the need for physiological variables in the prediction of outcome in high-risk infants...
  28. ncbi The term comorbidity is of questionable value in reference to developmental disorders: data and theory
    B J Kaplan
    Department of Paediatrics, University of Calgary, Alberta, Canada
    J Learn Disabil 34:555-65. 2001
    ..We discuss the concept of atypical brain development as an explanatory idea to interpret the high rate of overlap of developmental disorders...
  29. ncbi Multidisciplinary management in geriatric day-hospital is beneficial for elderly fallers: a prospective study of 28 cases
    Patrick Manckoundia
    Service de Médecine Interne Gériatrique Hôpital de Champmaillot CHU, BP 87 909, 2, rue Jules Violle, F 21 079 Dijon Cedex, France
    Arch Gerontol Geriatr 44:61-70. 2007
    ..This study shows the importance of a multidisciplinary management of elderly fallers with PDS...
  30. ncbi Bowen-Conradi syndrome: a clinical and genetic study
    R B Lowry
    Department of Medical Genetics, Alberta Children s Hospital and the University of Calgary, Canada
    Am J Med Genet A 120:423-8. 2003
    ..For those who were not seen, their clinical record were scrutinized. Pedigree analysis of all 39 was done and kinship coefficients computed. The birth prevalence was estimated to be 1/355 live births...
  31. ncbi Cardiovascular characteristics and cerebral CT findings in elderly subjects with psychomotor disadaptation syndrome
    Pierre Pfitzenmeyer
    Service de médecine gériatrique, Centre Hospitalier Regional et Universite de Dijon, France
    Aging Clin Exp Res 14:100-7. 2002
    ..The aim of this study was to complete the clinical picture, record cardiovascular risk factors and provide cerebral CT scan findings in patients with PDS...
  32. pmc Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome
    Joy Armistead
    Department of Biochemistry and Medical Genetics, University of Manitoba, MB, Canada
    Am J Hum Genet 84:728-39. 2009
    ..These findings suggested that the D-to-G mutation caused aggregation of EMG1, thereby reducing the level of the protein and causing BCS...
  33. ncbi Ethnic differences in achievement of developmental milestones by 9 months of age: The Millennium Cohort Study
    Yvonne Kelly
    Department of Epidemiology and Public Health, University College London, London, UK
    Dev Med Child Neurol 48:825-30. 2006
    ....
  34. ncbi Digitized analysis of abnormal hand-motor performance in schizophrenic patients
    P Tigges
    Department of Psychiatry, Ludwig Maximilians University Munich, Clinical Neurophysiology Section, Nussbaumstrasse 7, D 80336, Munich, Germany
    Schizophr Res 45:133-43. 2000
    ..Our findings show NSS in schizophrenic patients, independently of neuroleptics. Further, the hypothesis of lateralization of cerebral structures generating NSS towards the right hemisphere in schizophrenia is supported...
  35. ncbi Performance of diadochokinetic movements in schizophrenic patients
    Albert Putzhammer
    Movement Disorders Unit, Department of Psychiatry, University of Regensburg, Regensburg, Germany
    Schizophr Res 79:271-80. 2005
    ..This deficit is significantly worsened by conventional antipsychotic treatment. Antipsychotic treatment additionally reduces the enhancing effect of an attentional strategy on motor performance...
  36. ncbi Mini motor test: a clinical test for rehabilitation of patients showing psychomotor disadaptation syndrome (PDS)
    France Mourey
    Service de médecine gériatrique, Centre Hospitalier Regional, Université de Dijon, Centre de Champmaillot, 2 rue Jules Violle BP 87909, 21079 Dijon Cedex, France
    Arch Gerontol Geriatr 40:201-11. 2005
    ..This test can be used in clinical practice by different professional actors in order to allow an interdisciplinary approach for a common rehabilitation goal in the PDS patients...
  37. ncbi Fatigue-related impairment in the speed, accuracy and variability of psychomotor performance: comparison with blood alcohol levels
    Paul Maruff
    School of Psychology, La Trobe University, Bundoora, Vic, Australia
    J Sleep Res 14:21-7. 2005
    ..08%BAC. This suggests that previous studies that have not accounted for variability in the performance data have overestimated the effect of fatigue on cognitive performance...
  38. ncbi Neuropsychology of academic and behavioural limitations in school-age survivors of bacterial meningitis
    Irene Koomen
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Dev Med Child Neurol 46:724-32. 2004
    ....
  39. ncbi Proficiency of balance in children and youth who have had acute lymphoblastic leukemia
    Marilyn J Wright
    McMaster Children s Hospital, Box 2000, Hamilton, Ontario, Canada, L8N 3Z5
    Phys Ther 85:782-90. 2005
    ....
  40. ncbi Longitudinal associations between blood lead concentrations lower than 10 microg/dL and neurobehavioral development in environmentally exposed children in Mexico City
    Martha M Téllez-Rojo
    Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico
    Pediatrics 118:e323-30. 2006
    ..Using data from a prospective study conducted in Mexico City, Mexico, we evaluated the dose-effect relationship between blood lead levels and neurodevelopment at 12 and 24 months of age...
  41. ncbi Neurodevelopmental delays in children with deformational plagiocephaly
    Rouzbeh K Kordestani
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Oklahoma School of Medicine, Health Science Center, Oklahoma City, Oklahoma, USA
    Plast Reconstr Surg 117:207-18; discussion 219-20. 2006
    ..Through this study, we chose to expand upon our earlier findings from 2001 on patients with deformational plagiocephaly...
  42. ncbi Handwriting performance in preterm children compared with term peers at age 6 to 7 years
    Katya P Feder
    Rehabilitation Science, School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada
    Dev Med Child Neurol 47:163-70. 2005
    ..These findings may help guide early identification efforts and medical/therapeutic interventions for preterm children...
  43. ncbi Development of early motor skills and language in children at risk for familial dyslexia
    Helena Viholainen
    Niilo Maki Institute, Jyvaskyla, Finland
    Dev Med Child Neurol 44:761-9. 2002
    ..Children with familial risk for dyslexia and slow motor development had a smaller vocabulary and produced shorter sentences than the all other children. Associations between motor and language difficulties are discussed...
  44. ncbi Neurological and developmental outcome of neonatal jaundice and sepsis in rural Kenya
    Anne L Gordon
    Centre for Geographic Medicine Research Coast, KEMRI Wellcome Trust Research Laboratories, Kilifi, Kenya
    Trop Med Int Health 10:1114-20. 2005
    ..Since NS is common in resource poor countries, this may be an important cause of neuro-developmental impairment in children living in this setting...
  45. ncbi Association of symptoms and executive function in schizophrenia and bipolar disorder
    Eugenia Kravariti
    Department of Psychiatry, Division of Psychological Medicine, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 74:221-31. 2005
    ..Executive dysfunction in patients with psychotic disorders may be more related to their symptom profile than their diagnosis...
  46. ncbi [The characteristics of non-verbal learning disorder]
    E Rigau Ratera
    Hospital Santa Creu i Sant Pau, Barcelona, Espana
    Rev Neurol 38:S33-8. 2004
    ..Bearing in mind the similarity between NLD and Asperger's syndrome, we have also attempted to highlight the differences between the two developmental disorders...
  47. pmc Can the Griffiths scales predict neuromotor and perceptual-motor impairment in term infants with neonatal encephalopathy?
    A L Barnett
    Department of Paediatrics, Imperial College School of Medicine, Hammersmith Campus, London, UK
    Arch Dis Child 89:637-43. 2004
    ..To examine the predictive value of early developmental testing for identifying neuromotor and perceptual-motor impairment at school age in children with neonatal encephalopathy (NE)...
  48. ncbi Mental retardation and epilepsy in patients with isolated cerebellar hypoplasia
    Patrizia Ventura
    Department of Neurological and Psychiatric Sciences, Child Neuropsychiatric Service, University of Bari, Piazza Giulio Cesare, 70124 Bari, Italy
    J Child Neurol 21:776-81. 2006
    ..4%) and cognitive impairment (85.7%). Moreover, the tendency toward abnormal electroencephalographic (EEG) findings (78.5%), associated in a minor percentage of cases with epilepsy (28.5%), is also evident in our study...
  49. ncbi Review of three tests of motor proficiency in children
    Dustin Y Yoon
    Johns Hopkins University School of Nursing, Baltimore, MD 21205, USA
    Percept Mot Skills 102:543-51. 2006
    ..The selection criteria, interrater reliability, reproducibility, and recommended use of each test are reported here. Recommendations for use of each test include standardization of the sample population to ensure its appropriateness...
  50. ncbi Predicting motor outcome at preschool age for infants tested at 7, 30, 60, and 90 days after term age using the Test of Infant Motor Performance
    Thubi H A Kolobe
    Department of Rehabilitation Science, University of Oklahoma Health Sciences Center, 801 NE 13th St, Oklahoma City, OK 73104, USA
    Phys Ther 84:1144-56. 2004
    ....
  51. ncbi Very preterm birth is associated with disabilities in multiple developmental domains
    Anneloes L van Baar
    Department of Psychology and Health, Pediatric Psychology, Tilburg University, Tilburg, The Netherlands
    J Pediatr Psychol 30:247-55. 2005
    ..Presence of disabilities in more than one developmental domain will show a more serious outcome picture for extreme preterm infants and may be related to a different degree of perinatal problems...
  52. ncbi Neurocognitive performance and functional disability in the psychosis prodrome
    Tara A Niendam
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
    Schizophr Res 84:100-11. 2006
    ..This study evaluates the pattern of neuropsychological deficits and their association with clinical symptomatology and social functioning in individuals identified as ultra-high-risk (UHR) for psychosis...
  53. ncbi [Somatic and psychomotor development of preterm infants at the age of 2 years, with and without bronchopulmonary dysplasia]
    Przemko Kwinta
    Klinika Chorób Dzieci Katedry Pediatrii, Uniwersytet Jagielloński, ul Wielicka 265, 30 663 Kraków, Poland
    Med Wieku Rozwoj 9:271-81. 2005
    ..The assessment of psychomotor and somatic development at the age of 2 years of preterm infants with and without bronchopulmonary dysplasia (BPD)...
  54. pmc Neurological abnormalities in young adults born preterm
    M Allin
    Section of General Psychiatry, Division of Psychological Medicine, Box 063, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
    J Neurol Neurosurg Psychiatry 77:495-9. 2006
    ..It is currently not known whether neurological signs detected in VPT children persist into adulthood or become attenuated by maturation of the CNS...
  55. ncbi Transcranial micropolarization in the combined therapy of speech and general psychomotor retardation in children of late preschool age
    V A Ilyukhina
    Institute of the Human Brain, Russian Academy of Sciences, St Petersburg, Russia
    Neurosci Behav Physiol 35:969-76. 2005
    ....
  56. ncbi A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder
    Robin M Murray
    Institute of Psychiatry, Psychological Medicine, Denmark Hill, DeCrespigny Park, London SE5 8AF, UK
    Schizophr Res 71:405-16. 2004
    ....
  57. ncbi Disabilities and cognition in children and adolescents with 22q11 deletion syndrome
    S Oskarsdóttir
    The Queen Silvia Children s Hospital, Department of Paediatrics, Sahlgrenska Academy at Goteborg University, SE 416 85 Goteborg, Sweden
    Dev Med Child Neurol 47:177-84. 2005
    ..Although the severity and number of problems varies, the combination of impairments and disabilities results in a low level of participation...
  58. ncbi Epileptic features of patients with unilateral and bilateral schizencephaly
    Camila F Lopes
    Department of Neurology, State University of Campinas UNICAMP, CEP 13083 970, Campinas, SP, Brazil
    J Child Neurol 21:757-60. 2006
    ..In addition, the type of schizencephaly (open lip versus closed lip) does not correlate with the presence of epilepsy or seizure control, unlike motor deficit...
  59. ncbi Psychological and neurobehavioral comparisons of children with Asperger's Disorder versus High-Functioning Autism
    Linda L Thede
    Psychology Department, University of Colorado at Colorado Springs, PO Box 7150, Colorado Springs, CO 80933 7150, USA
    J Autism Dev Disord 37:847-54. 2007
    ..There were more similarities than differences between the two clinical samples on the personality scales, although the Asperger's group scored significantly on the two scales with anxiety components...
  60. pmc Cocaine, anemia, and neurodevelopmental outcomes in children: a longitudinal study
    Suchitra Nelson
    Department of Community Dentistry, School of Dentistry, Case Western Reserve University, Cleveland, Ohio 44106 4905, USA
    J Dev Behav Pediatr 25:1-9. 2004
    ..These findings indicate the need for greater pediatric surveillance of IDA and lead in cocaine-exposed infants, in order to reduce long-term neuropsychological deficits...
  61. ncbi Psychomotor development in children with early diagnosed giant interhemispheric cysts
    Fritz Haverkamp
    Paediatric Department, Children s Hospital, Rheinische Friedrich Wilhelms Universitaet, Bonn, Germany
    Dev Med Child Neurol 44:556-60. 2002
    ....
  62. ncbi Predictive validity of the test of infant motor performance as measured by the Bruininks-Oseretsky test of motor proficiency at school age
    Judy Flegel
    Curative Rehabilitation Services, 4069 N Prospect, Milwaukee, WI 53211, USA
    Phys Ther 82:762-71. 2002
    ..This study examined the predictive validity of the Test of Infant Motor Performance (TIMP) and the relationship between perinatal risk and motor performance in children who are of school age...
  63. ncbi Approaches to neurodevelopmental assessment in congenital diaphragmatic hernia survivors
    Catherine Chen
    Department of Surgery, Children s Hospital, Boston, MA 02115, USA
    J Pediatr Surg 42:1052-6; discussion 1056. 2007
    ....
  64. ncbi Neuropsychiatric findings of Möbius sequence -- a review
    W Briegel
    Department of Child and Adolescent Psychiatry and Psychotherapy, Bezirkskrankenhaus Passau, Passau, Germany
    Clin Genet 70:91-7. 2006
    ....
  65. ncbi Neurodevelopmental outcome for extended cold water drowning: a longitudinal case study
    Susannah Kury Hughes
    William Stixrud, Ph D, and Associates, Silver Spring, Maryland 20910, USA
    J Int Neuropsychol Soc 8:588-95. 2002
    ..This case demonstrates the need for long-term neuropsychological follow-up of pediatric patients with histories of neurologic injury, as gross neurological examination and MRI and MEG scans may not reveal underlying brain dysfunction...
  66. ncbi A randomised placebo-controlled trial of the effects of midazolam premedication on children's postoperative cognition
    K Millar
    University of Glasgow, Section of Psychological Medicine, Gartnavel Royal Hospital, 1055 Great Western Road, Glasgow G12 0XH, UK
    Anaesthesia 62:923-30. 2007
    ..The results show significant short-term impairment of children's cognitive function and amnesia enduring for 48 h after low-dose midazolam premedication...
  67. ncbi Neurocognitive development of young children with sickle cell disease through three years of age
    Robert J Thompson
    Duke University Medical Center, USA
    J Pediatr Psychol 27:235-44. 2002
    ....
  68. ncbi Predictive values of cranial ultrasound and assessment of general movements for neurological development of preterm infants in the Maribor region of Slovenia
    Polona Seme-Ciglenecki
    Center for Children with Developmental Disabilities, Dispensary for Children, Maribor Public Health Center, Maribor, Slovenia
    Wien Klin Wochenschr 119:490-6. 2007
    ....
  69. ncbi Performance on the Movement Assessment Battery for Children by Australian 3- to 5-year-old children
    D Livesey
    School of Psychology, University of Sydney, Sydney, NSW, Australia
    Child Care Health Dev 33:713-9. 2007
    ..Additionally, a 3-year-old sample was tested to determine if the test is suitable for discriminating motor performance in this age group...
  70. ncbi Predicting neuropsychological development from skull imaging
    H J Lin
    Dept of Med Educ and Biomed Informatics, Univ of Washington, Seattle, WA, USA
    Conf Proc IEEE Eng Med Biol Soc 1:3450-5. 2006
    ....
  71. ncbi Patterns of developmental dyscalculia with or without dyslexia
    Patrizio E Tressoldi
    Dipartimento di Psicologia, Generale Università di Padova, Padova, Italy
    Neurocase 13:217-25. 2007
    ..These findings add convergent support to the evidence mainly obtained from group comparisons that the more distinctive characteristics of dyscalculia are functionally independent of dyslexia...
  72. ncbi 'Hyper-priming' in thought-disordered schizophrenic patients
    S Moritz
    , , Hamburg, Germany
    Psychol Med 31:221-9. 2001
    ....
  73. ncbi Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia
    F Menni
    , , Centre Hospitalier Universitaire Necker-Enfants Malades, Paris, France
    Pediatrics 107:476-9. 2001
    ..CONCLUSION: Neonatal hyperinsulinemic hypoglycemia is still a severe disease with an important risk to rapidly develop severe mental retardation and epilepsy...
  74. pmc Brief report: autistic symptoms, developmental regression, mental retardation, epilepsy, and dyskinesias in CNS folate deficiency
    Paolo Moretti
    Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Autism Dev Disord 38:1170-7. 2008
    ..These findings demonstrate that autistic features are salient in CFD and suggest that a subset of children with developmental regression, mental retardation, seizures, dyskinesia, and autism may have CNS folate abnormalities...
  75. ncbi Neurodevelopmental outcomes of congenital diaphragmatic hernia survivors followed in a multidisciplinary clinic at ages 1 and 3
    Sandra Friedman
    Department of Medicine, Children s Hospital, Boston, MA 02115, USA
    J Pediatr Surg 43:1035-43. 2008
    ..We evaluated the relationship between medical and neurodevelopmental outcomes of CDH survivors seen in a multidisciplinary clinic at ages 1 and/or 3...
  76. ncbi Neurobehavioral profile and brain imaging study of the 22q13.3 deletion syndrome in childhood
    Anne Philippe
    National Institute of Health and Medical Research and Department of Genetics, Necker Enfants Malades Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Pediatrics 122:e376-82. 2008
    ..Our goal is to contribute to the description of the neurobehavioral phenotype and brain abnormalities of this microdeletional syndrome...
  77. ncbi Children with a schizophrenic disorder: neurobehavioral studies
    R F Asarnow
    Department of Psychiatry, University of California, Los Angeles 90024, USA
    Eur Arch Psychiatry Clin Neurosci 245:70-9. 1995
    ..It is argued that the developmental delays observed in schizophrenic children represent the greater time it takes them to automate certain skills. The delay in automation may reflect their limited information-processing capacity...
  78. ncbi Executive and emotional dysfunction in Machado-Joseph disease
    Tricia M Zawacki
    Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Mov Disord 17:1004-10. 2002
    ..Impaired executive abilities and emotional functioning in MJD patients is consistent with disruption of frontal-subcortical systems...
  79. ncbi Developmental coordination disorder at 8 years of age in a regional cohort of extremely-low-birthweight or very preterm infants
    N M Davis
    Department of Obstetrics and Gynaecology, Royal Women s Hospital, Carlton, Victoria, Australia
    Dev Med Child Neurol 49:325-30. 2007
    ..DCD is more common in ELBW/very preterm children, has few perinatal correlates, and is associated with poor cognitive and academic performance as well as increased behaviour problems...
  80. pmc Perceptual deficits in clumsy children: inter- and intra-modal matching approach--a window into clumsy behavior
    H Sigmundsson
    Research Group for Child Development, Norwegian University of Science and Technology, Trondheim, Norway
    Neural Plast 10:27-38. 2003
    ..Such an approach allows parallels to be drawn between behavioral manifestations of motor impairment and potential underlying neurological information-processing disorders, particularly as these relate to hemispheric competence...
  81. ncbi Manganese, monoamine metabolite levels at birth, and child psychomotor development
    Larissa Takser
    Institut National de la Santé et de la Recherche Médicale INSERM U472, Recherche en Epidemiologie et en Biostatistique, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France
    Neurotoxicology 24:667-74. 2003
    ..These results suggest that environmental Mn exposure in utero could affect early psychomotor development...
  82. pmc Neuropsychological assessment in HTLV-1 infection: a comparative study among TSP/HAM, asymptomatic carriers, and healthy controls
    M T T Silva
    The Federal University of Rio de Janeiro and Evandro Chagas Clinical Research Institute FIOCRUZ, Brazil
    J Neurol Neurosurg Psychiatry 74:1085-9. 2003
    ..To further clarify this the authors evaluated, through neuropsychological testing patients with TSP/HAM and asymptomatic infected carriers, comparing both groups with healthy controls...
  83. ncbi Neurocognitive impairment in early adolescence following prenatal alcohol exposure of varying duration
    Marit Korkman
    Department of Child Neurology, Helsinki University Central Hospital, Helsinki, Finland
    Child Neuropsychol 9:117-28. 2003
    ..Attention and executive functions do not seem to be selectively affected. Further, the relationship between duration of prenatal alcohol exposure and neurocognitive development continues to be significant in early adolescence...
  84. ncbi Teenage outcome after being born at term with moderate neonatal encephalopathy
    Katarina Lindström
    Department of Neuropediatrics, Children s Hospital, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Pediatr Neurol 35:268-74. 2006
    ..Clinical follow-up, including assessments of cognitive functions before school start, should be considered for all individuals in this high-risk group...
  85. ncbi A new Stroop-like measure of inhibitory function development: typical developmental trends
    Ingram Wright
    Academic Unit of Psychiatry and Behavioural Sciences, University of Leeds, UK
    J Child Psychol Psychiatry 44:561-75. 2003
    ..Difficulties with inhibition are increasingly regarded as central to pathological behavioural and learning disorders in childhood. However, few measures are available to assist in the assessment of young children's inhibitory competence...
  86. ncbi Predictors of outcome among high functioning children with autism and Asperger syndrome
    P Szatmari
    McMaster University, Canada
    J Child Psychol Psychiatry 44:520-8. 2003
    ..The objective of this paper is to assess the extent to which measures of cognitive abilities taken in an inception cohort of young high functioning children with autism and Asperger syndrome predict outcome roughly two and six years later...
  87. ncbi Effect of iron-deficiency anemia on cognitive skills and neuromaturation in infancy and childhood
    Tomas Walter
    Institute of Nutrition and Food Technology, University of Chile, Santiago
    Food Nutr Bull 24:S104-10. 2003
    ..The proposed mechanisms are altered auditory-nerve and vagal-nerve myelination, respectively, as iron is required for normal myelin synthesis...
  88. ncbi Prevalence estimations of attention-deficit/hyperactivity disorder: differential diagnoses and comorbidities in a Colombian sample
    David A Pineda
    Antioquia Neurosciences Group, University of Antioquia Medellin, Colombia
    Int J Neurosci 113:49-71. 2003
    ..8%, DCD 3.0%, and mild mental retardation 3.9%. Prevalence of ADHD did not show differences by socioeconomic status (SES), in contrast to mild mental retardation in which BIF and DCD were significantly more frequent in the lower SES...
  89. ncbi Role of processing speed and depressed mood on encoding, storage, and retrieval memory functions in patients diagnosed with schizophrenia
    Gildas Brébion
    Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    J Int Neuropsychol Soc 13:99-107. 2007
    ..Neither processing speed nor depressed mood was associated with storage efficiency. It is concluded that both cognitive speed slowing and depressed mood impact on effortful encoding processes...
  90. ncbi Neurocognitive functioning in children with type-1 diabetes with and without episodes of severe hypoglycaemia
    Riitta Hannonen
    Department of Child Neurology, Kymenlaakso Central Hospital, Kotka, Finland
    Dev Med Child Neurol 45:262-8. 2003
    ..Significant differences were found in verbal short-term memory and phonological processing. Results suggest that severe hypoglycaemia is a risk factor for learning due to deficits in auditory-verbal functioning...
  91. ncbi Cryptogenic localization related epilepsy in children from a tertiary outpatient clinic: is neurological and neuropsychological outcome predictable?
    Rianne P Reijs
    Department of Research and Development, Epilepsy Centre Kempenhaeghe, Heeze, The Netherlands
    Clin Neurol Neurosurg 109:422-30. 2007
    ..Also, we analysed correlations with risk and prognostic factors...
  92. ncbi Agyria-pachygyria: clinical, neuroimaging, and neurophysiologic correlations
    Jao Shwann Liang
    Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
    Pediatr Neurol 27:171-6. 2002
    ..We conclude that somatosensory-evoked potential examination is supplemental to neuroimaging in predicting the neurologic prognosis of patients with agyria-pachygyria...
  93. ncbi Cognitive and neuropsychological outcomes: more than IQ scores
    Glen P Aylward
    Division of Developmental and Behavioral Pediatrics, Department of Pediatrics, Southern Illinois University School of Medicine, Springfield, Illinois 62794 9658, USA
    Ment Retard Dev Disabil Res Rev 8:234-40. 2002
    ..In addition to IQ and achievement testing in follow-up, there should be evaluation of executive functions and attention, language, sensorimotor functions, visuospatial processes, memory and learning, and behavioral adjustment...
  94. ncbi Disturbed neural circuits in a subtype of chronic catatonic schizophrenia demonstrated by F-18-FDG-PET and F-18-DOPA-PET
    M Lauer
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Federal Republic of Germany
    J Neural Transm 108:661-70. 2001
    ..scenic and coenaestetic hallucinations are the most prominent psychopathological symptoms aside from psychomotor disorders in speech-sluggish catatonia, a subtype of chronic catatonic schizophrenia according to Karl Leonhard...
  95. ncbi [Autoimmune neuropsychiatric disorders associated to infection by streptococcus in the paediatric age: PANDAS]
    Y M Betancourt
    Universidad de Carabobo, Valencia, Venezuela
    Rev Neurol 36:S95-107. 2003
    ..The acronym PANDAS (Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus) describes the neuropsychiatric disorders resulting from an autoimmune response to an infection by streptococcus in children...
  96. ncbi Digital cineradiographic study of swallowing in infants with neurologic disease. Our experience
    Filippo Barbiera
    Dipartimento di Diagnostica per Immagini, Azienda Ospedaliera Universitaria Policlinico, Universita degli Studi, Palermo
    Radiol Med 107:286-92. 2004
    ....
  97. ncbi Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine
    H H Van Tol
    Department of Pharmacology, University of Toronto, Ontario, Canada
    Nature 350:610-4. 1991
    ..Dopamine receptors are primary targets for drugs used in the treatment of psychomotor disorders such as Parkinson's disease and schizophrenia...
  98. ncbi OCD-Like behaviors caused by a neuropotentiating transgene targeted to cortical and limbic D1+ neurons
    K M Campbell
    Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Neurosci 19:5044-53. 1999
    ..restricted to different D1+ CNS subsets in different transgenic lines, we observed distinct but related psychomotor disorders in different D1CT-expressing founders...
  99. ncbi Cavum veli interpositi cyst: prenatal diagnosis and postnatal outcome
    V D'Addario
    Department of Gynaecology, Obstetrics and Neonatology, University Medical School, Bari, Italy
    Ultrasound Obstet Gynecol 34:52-4. 2009
    ..The aim of this study was to report our experience of the sonographic findings and outcome of fetuses affected by CVI cysts...
  100. pmc Expression of Cre recombinase in dopaminoceptive neurons
    Thomas Lemberger
    German Cancer Research Center, 69120 Heidelberg, Germany
    BMC Neurosci 8:4. 2007
    ..locomotor and emotional responses and alterations in dopamine-signaling are responsible of several psychomotor disorders. In order to identify specific functions of these pathways, the Cre/loxP system has been used...
  101. ncbi Human dopamine D1 receptor encoded by an intronless gene on chromosome 5
    R K Sunahara
    Department of Pharmacology, University of Toronto, Ontario, Canada
    Nature 347:80-3. 1990
    ..Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and ..

Research Grants66

  1. Functional organization of neural circuits underlying movement control
    Jun Ding; Fiscal Year: 2011
    ..Dysfunction of basal ganglia neural network activity leads to a plethora of psychomotor disorders, including Parkinson's disease (PD), Huntington's disease (HD), and addiction...
  2. Functional organization of neural circuits underlying movement control
    Jun Ding; Fiscal Year: 2013
    ..Dysfunction of basal ganglia neural network activity leads to a plethora of psychomotor disorders, including Parkinson's disease (PD), Huntington's disease (HD), and addiction...
  3. DOPAMINERGIC AND MUSCARINIC SIGNALING IN THE STRIATUM
    DALTON SURMEIER; Fiscal Year: 2002
    Disorders in neostriatal dopaminergic and cholinergic signaling underlie a wide variety of psychomotor disorders. One of these disorders- Parkinson's disease (PD)-afflicts roughly 1 in every 1000 adults, rising exponentially in incidence ..
  4. NEUROIMAGING OF HIV AND COMORBID DISORDERS
    Lance Bauer; Fiscal Year: 2003
    ..An analysis of change scores across groups will permit a formal test of the effects of antiviral treatment on neurophysiological status. ..
  5. Abuse-Related Effects of Opioids and Adjuvant Drug Used by Chronic Pain Patients
    James P Zacny; Fiscal Year: 2010
    ..g., muscle relaxant B) would be the preferred drug to prescribe when treating chronic nonmalignant pain patients. ..
  6. BEHAVIORAL EFFECTS OF OPIOIDS IN VOLUNTEERS
    James Zacny; Fiscal Year: 2009
    ..abstract_text> ..
  7. Genetic Versus Phenotypic Markers of Relapse Risk
    Lance Bauer; Fiscal Year: 2009
    ....
  8. RATIONAL PHARMACOTHERAPY OF PRIMARY INSOMNIA
    Daniel Buysse; Fiscal Year: 2004
    ..The Principal Investigator will mentor trainees in analyses of existing data, design and implementation of the clinical trial, described above, and new studies designed by the trainees themselves. ..
  9. CHARACTERIZING PSYCHOACTIVE EFFECTS OF INHALANTS
    James Zacny; Fiscal Year: 2004
    ..In short, in our two proposed series of studies, we are developing a human laboratory model of inhalant abuse by studying potential determinants of abuse liability of inhalants (volatile and gaseous) in healthy volunteers. ..
  10. Insular AD Pathology and Autonomic Function
    Donald Royall; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  11. Literacy & cognitive skills to understand HIV regimens
    Drenna Waldrop Valverde; Fiscal Year: 2006
    ..Initial comprehension of ARV regimens is essential for continued adherence. Identification of factors related to poor comprehension of ARV medication instructions is a necessary prerequisite for developing interventions to improve it. ..
  12. NEGATIVE COGNITION DEPRESSION: ETIOLOGY AND COURSE
    LAUREN ALLOY; Fiscal Year: 2003
    ..abstract_text> ..
  13. Mental Practice Dosing and Mechanisms in Stroke
    Stephen Page; Fiscal Year: 2006
    ..Identification of MP mechanisms of action and optimal dosing is fundamental to cost-effective, appropriate implementation of this promising, CAM, mind-body technique, and will enable a subsequent MP clinical trial. ..
  14. Behavioral Approach System (BAS)and Bipolar Spectrum: Biopsychosocial Integration
    LAUREN ALLOY; Fiscal Year: 2007
    ..Finally, these same factors will be examined to predict general worsening of course and progression to Bi II and Bi I status among the Bi Ss. ..
  15. Tryptophan Metabolism, Genes, and Major Depression
    David Steffens; Fiscal Year: 2007
    ..Results from this study will help inform future treatment studies using genetics and metabolomic technology. [unreadable] [unreadable] [unreadable]..
  16. CEREBELLAR STRUCTURE AND FUNCTION IN ALCOHOLISM
    Edith Sullivan; Fiscal Year: 2008
    ..abstract_text> ..
  17. Characterization of Familial Myopathy & Paget Disease
    Virginia Kimonis; Fiscal Year: 2005
    ..Elucidation of the genetic defect will help us understand the pathogenesis of this multifaceted disorder and hopefully result in specific therapy. ..
  18. Stress Reactivity & Protective Factors in Schizophrenia
    Joseph Ventura; Fiscal Year: 2003
    ..abstract_text> ..
  19. Benzodiazepine Use/Abuse: Effects on Memory Mechanisms
    MIRIAM MINTZER; Fiscal Year: 2008
    ..Information from this project can also be used to develop cognitive rehabilitation programs and to tailor drug abuse and anxiety treatment interventions to the specific capabilities of long-term users. ..
  20. Cognitive Training and Enhanced Supported Employment
    Morris D Bell; Fiscal Year: 2010
    ..FU, and 2 yr. FU will focus on cognitive and vocational outcomes, but will also include clinical status, quality of life and community function measures. Predictors of response to training will also be examined. ..
  21. DEVELOPMENT OF SIMULATIONS TO DETECT IMPAIRED DRIVERS
    Thomas Marcotte; Fiscal Year: 2003
    ..Potential markets include assessment of impaired drivers, monitoring of medication side effects, driver training and rehabilitation (alcohol, drugs, head injuries, disabilities, strokes, etc.), and driver education. ..
  22. Prospective Study: Alcoholic & Control Family Offspring
    Marc A Schuckit; Fiscal Year: 2010
    ..Our ultimate goal is to identify ways to prevent the escalation of drinking and associated problems in young populations. ..
  23. Neuroimaging of Benzodiazepine-Induced Amnesia
    MIRIAM MINTZER; Fiscal Year: 2003
    ..Results of the proposed research also will enhance the understanding of the functional neuroanatomy of basic human memory processes. ..
  24. Serotonin Club IUPHAR Satellite Meeting
    Mark Geyer; Fiscal Year: 2006
    ..Hence, helping neuroscientists-in-training attend the meeting will have a positive influence on trainees and a lasting impact on the field. [unreadable] [unreadable] [unreadable]..
  25. Aging, White Matter Changes, Executive Dysfunction and Depression
    Robert Young; Fiscal Year: 2007
    ..The clinical significance of the proposed study is that it can guide research leading to physiologically meaningful, novel antidepressant therapies aimed at aging-related frontal system dysfunction. [unreadable] [unreadable]..
  26. AGING AND DEMENTIA--LONGITUDINAL COURSE OF SUBGROUPS
    Barry Reisberg; Fiscal Year: 2002
    ..Collectively, these cohorts include over 1300 persons. The comprehensive evaluations include behavioral, mental status, neuropsychologic, neurologic, neuroimaging, electrophysiologic, and postmortem studies. ..
  27. The Manahattan HIV Brain Bank
    Susan Morgello; Fiscal Year: 2007
    ....
  28. RSA Lecture Series
    Jennifer Thomas; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  29. White matter integrity and autonomic stress response
    John Williamson; Fiscal Year: 2007
    ..heart rate variability, respiratory sinus arrhythmia), and conduction of an independent research project synthesizing these skills that will promote the development of an academic research career. [unreadable] [unreadable] [unreadable]..
  30. Effects of Opioid Pharmacotherapy on Functioning
    MIRIAM MINTZER; Fiscal Year: 2008
    ..Data from this project may also enhance the scientific understanding of pharmacological and cognitive mechanisms. ..
  31. STARTLE GATING AND LOCOMOTION IN D2-FAMILY KNOCKOUT MICE
    Mark Geyer; Fiscal Year: 2004
    ..This information will have important implications for the further development of therapeutic approaches to the treatment of both schizophrenia and drug abuse. ..
  32. ELSI Scale-Up: Large Sample Gene Discovery & Disclosure
    Donald Bailey; Fiscal Year: 2006
    ..abstract_text> ..
  33. Metabolic Syndrome in Adult Survivors of Childhood ALL
    James Gurney; Fiscal Year: 2005
    ..abstract_text> ..
  34. Aging, Vascular Disease and Cognition
    David Moser; Fiscal Year: 2007
    ..abstract_text> ..
  35. Prophylaxis of adrenal insufficiency to prevent CLD
    Kristi Watterberg; Fiscal Year: 2005
    ..If this study confirms the benefits seen in the pilot study, it will result in a significant improvement in health care for premature infants, both by introducing a beneficial new therapy, and by avoiding higher dose dexamethasone. ..
  36. Identifying Newborns with Fragile X: Planning Grant
    Donald Bailey; Fiscal Year: 2005
    ..abstract_text> ..
  37. Reducing pesticide exposures to farmworker children.
    Brenda Eskenazi; Fiscal Year: 2005
    ....
  38. Autonomic dysregulation in primary insomnia
    Gary Richardson; Fiscal Year: 2005
    ..Finally, we will use a new measure of central CRF function, the DEX-sleep latency test, to test the hypothesis that central CRF tone is higher in patients with P1. ..
  39. LANGUAGE COMPREHENSION AS STRUCTURE BUILDING
    MORTON GERNSBACHER; Fiscal Year: 2002
    ....
  40. Cerebro/peripheral vascular function in cognition
    David Moser; Fiscal Year: 2005
    ..The proposed research is expected to yield publishable results and will also provide valuable pilot data for larger scale (e.g. R01) grant applications. ..
  41. CONCEPTS AND LANGUAGE
    Anjan Chatterjee; Fiscal Year: 2006
    ..These studies will have theoretical implications for models of conceptual development and reasoning and practical implications for the treatment of aphasic patients. ..
  42. Predicting Decline in Mild Cognitive Impairment
    Kevin Duff; Fiscal Year: 2006
    ..abstract_text> ..
  43. Visual Cognition in Dementia with Lewy Bodies
    Joanne M Hamilton; Fiscal Year: 2010
    ....
  44. Detection of Dopamine Release During a Cognitive Task
    RAJENDRA BADGAIYAN; Fiscal Year: 2006
    ..This study will determine whether the molecular imaging technique can be reliably used to investigate an unexplored aspect (neurotransmission) of human cognition. [unreadable] [unreadable]..
  45. Functional Limitation, Arthritis, Depression, & Race
    Dorothy Dunlop; Fiscal Year: 2006
    ..Hypotheses tested by this study will provide information that would motivate clinical and public health strategies to improve health care and reduce functional impairment among people with arthritis. [unreadable] [unreadable]..
  46. Latent Mobility Abnormalities And Frailty
    Joe Verghese; Fiscal Year: 2009
    ..abstract_text> ..
  47. Neurologic Predictors of Schizophrenia
    Jason Schiffman; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  48. NEGLECT AND SPATIAL REPRESENTATIONS
    Anjan Chatterjee; Fiscal Year: 2002
    ....
  49. In-Car Technology to Alert Attention-Imparied Drivers
    Matthew Rizzo; Fiscal Year: 2009
    ..The results may be used to design safer automobiles that use new strategies and technologies for collision warning, perceptual augmentation, and attention management. ..
  50. Genetic basis of myopathy with Paget disease of bone
    Virginia Kimonis; Fiscal Year: 2008
    ..e. effect on ATPase activity, protein-protein interactions, and hexamer formation). Study the VCP specific pathways in C2C12 cell lines (stably transfected wt and R155H VCP) during differentiation and under stress conditions...
  51. Constraint-Induced Therapy in Children with CP
    Andrew Gordon; Fiscal Year: 2003
    ..The resulting data will be used to determine inclusion and exclusion criteria, develop estimates of effect size, and refine the methods and outcome measures for future grant applications. ..
  52. VAS-COG 2007
    Donald Royall; Fiscal Year: 2007
    ..Many vascular cognitive disorders are preventable and potentially reversible. VAS-COG will provide a forum in which information on these important conditions can be exchanged and disseminated. [unreadable] [unreadable] [unreadable]..
  53. GENE CAUSING PAGET & LIMB-GIRDLE MUSCULAR DYSTROPHY
    Virginia Kimonis; Fiscal Year: 2003
    ..Delineation of the genetic component responsible for the LGMD/PDB phenotype should promise similar insight and facilitate in the design of novel treatment protocols for the two disorders. ..
  54. DEPRESSION DIAGNOSIS AND TREATMENT IN PARKINSON DISEASE
    Daniel Weintraub; Fiscal Year: 2008
    ..abstract_text> ..
  55. SAM-e Treatment of Depression in Parkinson's Disease
    Alessandro DiRocco; Fiscal Year: 2004
    ..abstract_text> ..
  56. Global vs. Focal Neuroimaging Markers of Dementia Risk
    Caterina Rosano; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  57. Pharmacogenetics in Tourette Syndrom
    Harvey Singer; Fiscal Year: 2004
    ..The identification of genetic polymorphisms that are associated with clinical disease or treatment success, has obvious benefits. ..
  58. PREVENTION OF GERATRIC DEPRESSION
    George Alexopoulos; Fiscal Year: 2003
    ..Accordingly, we are well positioned to meet the challenges inherent in this difficult but important area of research. ..
  59. Definition and Development of the Phenotype of Autism
    Sally Rogers; Fiscal Year: 2006
    ....
  60. Genetic damage in the sperm and blood of workers exposed to benzene
    Brenda Eskenazi; Fiscal Year: 2008
    ..Lastly, this study is one of the first to investigate the relative sensitivities of sperm and blood cells to chromosomal defects induced by benzene. [unreadable] [unreadable] [unreadable]..
  61. Predicting Driver Safety in Parkinson's Disease
    Ergun Uc; Fiscal Year: 2007
    ..Fair and accurate means of detecting unfit drivers with PD will help mitigate the tragedy of motor vehicle crashes caused by these impaired individuals. ..
  62. Cornell ACISR for Late Life Depression
    George Alexopoulos; Fiscal Year: 2007
    ..We are confident that our work will both advance scientific knowledge and have a broad impact on the care of depressed, disabled elders. ..
  63. Second International Brainstorming Meeting on Parkinson Disease: Nosology
    Irene Litvan; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  64. Identification of Novel Biomarkers in HD
    Tatiana Foroud; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  65. Longitudinal Studies Among At-Risk HD Gene Carriers
    Tatiana Foroud; Fiscal Year: 2006
    ..abstract_text> ..