Genomes and Genes
language development disorders
Summary: Conditions characterized by language abilities (comprehension and expression of speech and writing) that are below the expected level for a given age, generally in the absence of an intellectual impairment. These conditions may be associated with DEAFNESS; BRAIN DISEASES; MENTAL DISORDERS; or environmental factors.
Publications276 found, 100 shown here
- Genetic influences on language impairment and phonological short-term memoryDianne F Newbury
Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Headington, Oxford, OX3 7BN, UK
Trends Cogn Sci 9:528-34. 2005..Identifying those cognitive deficits that work best as indices of heritable phenotypes will help us to uncover the aetiology of developmental disorders...
- The Autism Diagnostic Observation Schedule: revised algorithms for improved diagnostic validityKatherine Gotham
University of Michigan Autism and Communication Disorders Center, Ann Arbor, MI, 48109 2054, USA
J Autism Dev Disord 37:613-27. 2007....
- Deviant functional magnetic resonance imaging patterns of brain activity to speech in 2-3-year-old children with autism spectrum disorderElizabeth Redcay
Department of Psychology, University of California, San Diego, California, USA
Biol Psychiatry 64:589-98. 2008..A failure to develop normal language is one of the most common first signs that a toddler might be at risk for autism. Currently the neural bases underlying this failure to develop language are unknown...
- Grammar predicts procedural learning and consolidation deficits in children with Specific Language ImpairmentMartina Hedenius
Unit for Speech and Language Pathology, Department of Neuroscience, University of Uppsala, PO Box 256, SE 751 05 Uppsala, Sweden
Res Dev Disabil 32:2362-75. 2011..In sum, this study clarifies our understanding of the underlying deficits in SLI, and suggests avenues for further research...
- A functional genetic link between distinct developmental language disordersSonja C Vernes
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
N Engl J Med 359:2337-45. 2008..Rare mutations affecting the FOXP2 transcription factor cause a monogenic speech and language disorder. We hypothesized that neural pathways downstream of FOXP2 influence more common phenotypes, such as specific language impairment...
- Exploration of serial structure procedural learning in children with language impairmentAudrey Gabriel
Department of Cognitive Science, University of Liege, Liege, Belgium
J Int Neuropsychol Soc 17:336-43. 2011..These results are novel and suggest that children with SLI do not display global procedural system deficits...
- Predicted and observed outcomes in preschool children following speech and language treatment: parent and clinician perspectivesNancy Thomas-Stonell
Bloorview Research Institute, Bloorview Kids Rehab, 150 Kilgour Road, Toronto, Ontario, Canada
J Commun Disord 42:29-42. 2009..New outcome measures need to be based on actual observations of change by both parents and clinicians to ensure that they measure a sufficiently broad-based range of skills...
- Research review: structural language in autistic spectrum disorder - characteristics and causesJill Boucher
Autism Research Group, City University, London, UK
J Child Psychol Psychiatry 53:219-33. 2012..This review aims to highlight the ubiquitousness of structural language anomalies and impairments in ASD, and to stimulate investigation of their immediate causes and implications for intervention...
- Contributing to the early detection of Rett syndrome: the potential role of auditory Gestalt perceptionPeter B Marschik
Institute of Physiology, IN spired, Developmental Physiology and Developmental Neuroscience, Center for Physiological Medicine, Medical University of Graz, Austria
Res Dev Disabil 33:461-6. 2012..This is important because clinical criteria related to speech and language development remain important for early identification of Rett syndrome...
- Atypical brain responses to sounds in children with specific language and reading impairmentsGenevieve McArthur
Macquarie Centre for Cognitive Science, Macquarie University, NSW, Australia
Dev Sci 12:768-83. 2009..A subgroup of these poor non-word readers also had poor non-word repetition. These findings support the hypothesis that impaired auditory processing is a causal risk factor for both SLI and SRD...
- Semantic, factual, and social language comprehension in adolescents with autism: an FMRI studyW B Groen
Karakter, Child and Adolescent Psychiatry University Center, Karakter, 6525 GC Nijmegen, The Netherlands
Cereb Cortex 20:1937-45. 2010..The results suggest that people with autism may recruit the LIF region in a different manner in tasks that demand integration of social information...
- Development of the FOCUS (Focus on the Outcomes of Communication Under Six), a communication outcome measure for preschool childrenNancy L Thomas-Stonell
Bloorview Research Institute affiliated with the University of Toronto, Toronto, ON, Canada
Dev Med Child Neurol 52:47-53. 2010....
- Screening for speech and language delay in preschool children: systematic evidence review for the US Preventive Services Task ForceHeidi D Nelson
Department of Medical Informatics, Oregon Health and Science University, Portland, Oregon 97239, USA
Pediatrics 117:e298-319. 2006..However, optimal methods for screening for speech and language delay have not been identified, and screening is practiced inconsistently in primary care...
- Early predictors of communication development in young children with autism spectrum disorder: joint attention, imitation, and toy playKaren Toth
Department of Psychology, UW Autism Center, CHDD, University of Washington 357920, Seattle, WA 98195, USA
J Autism Dev Disord 36:993-1005. 2006..5 years. The implications of these results for understanding the nature and course of language development in autism and for the development of targeted early interventions are discussed...
- Disruption of CNTNAP2 and additional structural genome changes in a boy with speech delay and autism spectrum disorderMartin Poot
Department of Medical Genetics, University Medical Centre Utrecht, Mail stop KC 04 084 2, P O Box 85090, 3508, Utrecht, The Netherlands
Neurogenetics 11:81-9. 2010..For full-blown ASD to develop, a proximal disruption of CNTNAP2 may have to occur concomitantly with additional genome mutations such as hemizygous deletions of the KCTD3 and USH2A genes...
- Lower-frequency event-related desynchronization: a signature of late mismatch responses to sounds, which is reduced or absent in children with specific language impairmentDorothy V M Bishop
Department of Experimental Psychology, University of Oxford, OX1 3UD Oxford, UK
J Neurosci 30:15578-84. 2010..This provides compelling evidence for a low-level auditory perceptual impairment in SLI that affects a processing stage after initial detection of a sound change...
- Reorganization of the cerebro-cerebellar network of language production in patients with congenital left-hemispheric brain lesionsK Lidzba
Department of Developmental Neurology, University Children s Hospital, Hoppe Seyler Str 1, Tubingen 72076, Germany
Brain Lang 106:204-10. 2008..We suggest that the developing brain reacts to early focal lesions in the left hemisphere with a mirror-image organization of the entire cerebro-cerebellar network engaged in speech production...
- Children with autism illuminate the role of social intention in word learningJulia Parish-Morris
Department of Psychology, Temple University, Philadelphia, PA 19122 6085, USA
Child Dev 78:1265-87. 2007....
- Narrative skills of children with communication impairmentsCourtenay Frazier Norbury
Oxford Study of Children s Communication Impairments, UK
Int J Lang Commun Disord 38:287-313. 2003..Comparing these two groups of children with children who exhibit pragmatic language impairment without autism may help to clarify these issues...
- Evaluation of a language-screening programme for 2.5-year-olds at Child Health Centres in SwedenC M Mattsson
Central Unit for Child Health Care, South Bohuslän, Västra Götaland, Sweden
Acta Paediatr 90:339-44. 2001..Baye's theorem was used to calculate the sensitivity (0.69) and the specificity (0.93) of the screening. A method of calculating the sensitivity and specificity of the test method by means of three samples was demonstrated...
- Early language impairment and young adult delinquent and aggressive behaviorE B Brownlie
Psychology Department, Simon Fraser University, Burnaby, British Columbia, Canada
J Abnorm Child Psychol 32:453-67. 2004..Language impairment was not related to aggression or delinquency in girls. We examine alternate models of the interrelationships between language, academics, and behavior, at ages 5, 12, and 19...
- A longitudinal study of behavioral, emotional and social difficulties in individuals with a history of specific language impairment (SLI)Michelle C St Clair
School of Psychological Sciences, Ellen Wilkinson Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK
J Commun Disord 44:186-99. 2011..Different aspects of early language abilities and reading skills exert different types and degrees of influence on behavioral, emotional and social difficulties...
- Further defining the language impairment of autism: is there a specific language impairment subtype?Andrew J O Whitehouse
Department of Experimental Psychology, Oxford Study of Children s Communication Impairments, University of Oxford, South Parks Road, Oxford OX1 3UD, United Kingdom
J Commun Disord 41:319-36. 2008..Further analyses suggested that the nonword repetition deficits experienced by some children with autism may arise when there is substantial impairment in multiple autistic domains...
- Uses and interpretations of non-word repetition tasks in children with and without specific language impairments (SLI)Jeffry A Coady
Department of Speech, Language, and Hearing Sciences, Sargent College, Boston University, Boston, MA, USA
Int J Lang Commun Disord 43:1-40. 2008..This task has gained wide acceptance because it so closely matches the phonological component of word learning, and correlates with measures of phonological working memory, a deficit in which is hypothesized to underlie SLI...
- Non-word repetition in adolescents with specific language impairment and autism plus language impairments: a qualitative analysisN G Riches
Guy s and St Thomas NHS Hospital Trust, Newcomen Centre, Guy s Hospital, London, SE1 9RT, UK
J Commun Disord 44:23-36. 2011..From a clinical perspective algorithms which automatically count phoneme errors may enhance sensitivity of NWR as a diagnostic marker of language impairment...
- A theory of neurolinguistic developmentJ L Locke
Massachusetts General Hospital and Harvard Medical School, USA
Brain Lang 58:265-326. 1997..The theory thus offers a different role for genetics and early experience, and a different interpretation of neuroanatomic findings, from those entertained in most other proposals on developmental language disorders...
- Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairmentNatalie R Powers
Department of Genetics, Yale University, 464 Congress Avenue, Suite 243, New Haven, CT 06520, USA
Am J Hum Genet 93:19-28. 2013..On the basis of these data, we propose a new name for BV677278: "READ1" or "regulatory element associated with dyslexia 1." ..
- Individual differences in lexical processing at 18 months predict vocabulary growth in typically developing and late-talking toddlersAnne Fernald
Stanford University, Stanford, CA 94305, USA
Child Dev 83:203-22. 2012....
- Developmental language impairment through the lens of the ICF: an integrated account of children's functioningLynn Dempsey
Brock University, Department of Applied Linguistics, 500 Glenridge Avenue, St Catharines, Ontario, Canada L2S 3A1
J Commun Disord 43:424-37. 2010....
- Parent based language intervention for 2-year-old children with specific expressive language delay: a randomised controlled trialA Buschmann
Department of Paediatric Neurology, Children s Hospital, University of Heidelberg, Im Neuenheimer Feld 150, D 69120 Heidelberg, Germany
Arch Dis Child 94:110-6. 2009....
- Early speech-language development in females with Rett syndrome: focusing on the preserved speech variantPeter B Marschik
Institute of Physiology IN spired Developmental Physiology and Developmental Neuroscience, Centre for Physiological Medicine, Medical University of Graz, Harrachgasse 21 5, Graz, Austria
Dev Med Child Neurol 54:451-6. 2012....
- Late onset canonical babbling: a possible early marker of abnormal developmentD K Oller
University of Maine, Orono 04469, USA
Am J Ment Retard 103:249-63. 1998..Late canonical-babbling onset may be a predictor of later developmental disabilities, including problems in speech, language, and reading...
- Preschoolers with autism show greater impairment in receptive compared with expressive language abilitiesKristelle Hudry
Centre for Research in Autism and Education, Department of Psychology and Human Development, Institute of Education, London, UK
Int J Lang Commun Disord 45:681-90. 2010..However, the relative degree of delay or impairment in each of these sub-domains may also be atypical and remains less well-understood...
- Non-word repetition and language development in children with specific language impairment (SLI)N Botting
School of Education, University of Manchester, Oxford Road, Manchester M13 9PL, UK
Int J Lang Commun Disord 36:421-32. 2001..A specific phonological memory difficulty may therefore be present over and above a subtle but more general processing limitation. The implications for SLI theory and practice are discussed...
- Growth of reading skills in children with a history of specific language impairment: the role of autistic symptomatology and language-related abilitiesMichelle C St Clair
The University of Manchester, UK
Br J Dev Psychol 28:109-31. 2010..These findings provide strong evidence that individuals with SLI experience continued, long-term deficits in reading skills from childhood to adolescence...
- Psychosocial outcomes at 15 years of children with a preschool history of speech-language impairmentMargaret J Snowling
Department of Psychology, University of York, Heslington, UK
J Child Psychol Psychiatry 47:759-65. 2006..The present study assessed the psychosocial adjustment in adolescence of young people with history of speech-language impairment, and investigated specific relationships between language deficits and psychiatric disorders...
- The acquisition of relative clause comprehension in Hebrew: a study of SLI and normal developmentNaama Friedmann
School of Education, Tel Aviv University, Tel Aviv, Israel
J Child Lang 31:661-81. 2004..The syntactic impairment is interpreted as a selective deficit to non-canonical sentences that are derived by movement...
- High heritability of speech and language impairments in 6-year-old twins demonstrated using parent and teacher reportDorothy V M Bishop
Department of Experimental Psychology, University of Oxford, Oxford, UK
Behav Genet 36:173-84. 2006..This study shows that there are strong genetic influences on both structural and pragmatic language impairments in children, and these can be detected using a simple checklist completed by parents or teachers...
- A randomized, controlled study of computer-based intervention in middle school struggling readersBarbara K Given
Krasnow Institute for Advanced Study, George Mason University, 4400 University Drive, Fairfax, VA 22030 4444, USA
Brain Lang 106:83-97. 2008..e., change for all participants over time), but no between-subject group differences, failing to show that Fast ForWord resulted in any gains over and above those seen in the other groups...
- Cost-effectiveness analysis of current practice and parent intervention for children under 3 years presenting with expressive language delayDeborah Gibbard
Speech and Language Therapy Department, Battenburg Avenue Clinic, Portsmouth, UK
Int J Lang Commun Disord 39:229-44. 2004..However, these alternative treatments have not been subject to rigorous comparative analysis in terms of both cost and clinical effectiveness...
- Individual differences in anatomy predict reading and oral language impairments in childrenChristiana Leonard
Department of Neuroscience, University of Florida, Gainesville, FL 32605, USA
Brain 129:3329-42. 2006..Reading impaired children with and without comprehension deficits appear to occupy neuroanatomical domains on the opposite sides of normal...
- Atypical functional lateralization of language in autism spectrum disordersNatalia M Kleinhans
Department of Radiology, University of Washington, Seattle, WA 98195, USA
Brain Res 1221:115-25. 2008..Abnormal functional organization may contribute to the language impairment seen in ASD...
- Language assessment and development in toddlers with autism spectrum disordersRHIANNON J LUYSTER
Autism Consortium, Boston, MA, USA
J Autism Dev Disord 38:1426-38. 2008..For expressive language, the most significant predictors were non-verbal cognitive ability, gestures and imitation. These findings have important implications for intervention programs targeting this population...
- Residual language deficits in optimal outcome children with a history of autismElizabeth Kelley
Department of Psychology, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT 06269 1020, USA
J Autism Dev Disord 36:807-28. 2006..Results indicated that while these children's grammatical capabilities are mostly indistinguishable from their peers, they are still experiencing difficulties in pragmatic and semantic language...
- Language outcomes of 7-year-old children with or without a history of late language emergence at 24 monthsMabel L Rice
3031 Dole Human Development Center, University of Kansas, 1000 Sunnyside Avenue, Lawrence, KS 66045, USA
J Speech Lang Hear Res 51:394-407. 2008..The aim of this study was to investigate the language outcomes of 7-year-old children with and without a history of late language emergence at 24 months...
- Domain-specific cognitive systems: insight from Grammatical-SLIHeather K J van der Lely
Centre for Developmental Language Disorders and Cognitive Neuroscience, Department of Human Communication Science, University College London, 2 Wakefield Street, London WC1E 1PF, UK
Trends Cogn Sci 9:53-9. 2005..Moreover, evidence suggests that impairment in at least one subgroup is specific to grammar...
- A cluster-randomized trial of screening for language delay in toddlers: effects on school performance and language development at age 8Heleen M E van Agt
Department of Public Health, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
Pediatrics 120:1317-25. 2007..The goal of this study was to assess the effects of screening and early treatment of preschool children for language delay on language development and school performance at age 8...
- Working memory in children with developmental disordersTracy Packiam Alloway
University of Stirling, United Kingdom
J Learn Disabil 42:372-82. 2009..The implications of these findings are discussed in light of support for learning...
- Prevalence and natural history of primary speech and language delay: findings from a systematic review of the literatureJ Law
Department of Language and Communication Science, City University, London, UK
Int J Lang Commun Disord 35:165-88. 2000..The results are discussed in terms of the need to develop a model of prevalence based on risk of subsequent difficulties...
- Predicting language outcomes at 4 years of age: findings from Early Language in Victoria StudySheena Reilly
Murdoch Children s Research Institute, Royal Children s Hospital, Speech Pathology Department, Flemington Road, Parkville, 3052, Australia
Pediatrics 126:e1530-7. 2010..To quantify the contributions of child, family, and environmental predictors to language ability at 4 years...
- Decreased left posterior insular activity during auditory language in autismJ S Anderson
Department of Neuroradiology, University of Utah, Salt Lake City, Utah 84132, USA
AJNR Am J Neuroradiol 31:131-9. 2010..We acquired functional MR images during an auditory language task to evaluate systematic differences in language-network activation between control and high-functioning autistic populations...
- Clinic attenders with autism or attention-deficit/hyperactivity disorder: cognitive profile at school age and its relationship to preschool indicators of language delayBibbi S Hagberg
Department of Child and Adolescent Psychiatry, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
Res Dev Disabil 31:1-8. 2010..In many cases early language delay, even in the absence of clear learning disability should be taken as a signal that - regardless of specific diagnosis - intellectual functioning might be in the low average range...
- Outcomes of early language delay: I. Predicting persistent and transient language difficulties at 3 and 4 yearsPhilip S Dale
Communication Sciences and Disorders, University of Missouri Columbia, 65211, USA
J Speech Lang Hear Res 46:544-60. 2003..Furthermore, measures of parental education and the child's history of ear infections failed to substantially improve the prediction...
- Modeling longitudinal change in the language abilities of children with autism: parent behaviors and child characteristics as predictors of changeMichael Siller
Department of Psychology, University of California, Los Angeles, USA
Dev Psychol 44:1691-704. 2008..These findings support a social?pragmatic view on language acquisition, which emphasizes the collaborative process through which children and their parents negotiate shared meaning...
- Non-specific nature of specific language impairment: a review of the literature with regard to concomitant motor impairmentsE L Hill
Department of Experimental Psychology, University of Cambridge, UK
Int J Lang Commun Disord 36:149-71. 2001....
- Electrophysiological evidence for delayed mismatch response in infants at-risk for specific language impairmentM Friedrich
Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Psychophysiology 41:772-82. 2004..This latency difference suggests that 2-month-old infants at risk for SLI are already affected in processing an auditory stimulus change of duration...
- Improving early language and literacy skills: differential effects of an oral language versus a phonology with reading interventionClaudine Bowyer-Crane
Department of Psychology, University of York, Heslington, York, UK
J Child Psychol Psychiatry 49:422-32. 2008..This study compares the efficacy of two school-based intervention programmes (Phonology with Reading (P + R) and Oral Language (OL)) for children with poor oral language at school entry...
- Language disorders: a 10-year research update reviewC O Toppelberg
Judge Baker Children s Center, Harvard Medical School, Boston, MA 02115, USA
J Am Acad Child Adolesc Psychiatry 39:143-52. 2000..To review the past 10 years of research in child language or communication disorders, which are highly prevalent in the general population and comorbid with childhood psychiatric disorders...
- Grammaticality judgements of an extended optional infinitive grammar: evidence from English-speaking children with specific language impairmentM L Rice
Child Language Doctoral Program, University of Kansas, Lawrence 66045, USA
J Speech Lang Hear Res 42:943-61. 1999..The findings support the extended optional infinitive (EOI) account of morphosyntactic limitation based in underlying grammatical representations and do not support accounts of input processing deficits or production constraints...
- Predictors of phrase and fluent speech in children with autism and severe language delayEricka L Wodka
Center for Autism and Related Disorders, Kennedy Krieger Institute, 3901 Greenspring Ave, Baltimore, MD 21211, USA
Pediatrics 131:e1128-34. 2013..We hypothesized greater autism symptomatology and lower intelligence among children who do not attain phrase/fluent speech, with nonverbal intelligence and social engagement emerging as the strongest predictors of outcome...
- Follow-up of children attending infant language units: outcomes at 11 years of ageG Conti-Ramsden
Human Communication and Deafness, School of Education, University of Manchester, Oxford Road, Manchester M13 9PL, UK
Int J Lang Commun Disord 36:207-19. 2001..A small group of 16 children appeared to have entirely resolved their difficulties. These outcomes and their implications for education and long-term impact of the disorder are discussed...
- Syntactic complexity during conversation of boys with fragile X syndrome and Down syndromeJohanna R Price
Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, USA
J Speech Lang Hear Res 51:3-15. 2008..This study compared the syntax of boys who have fragile X syndrome (FXS) with and without autism spectrum disorder (ASD) with that of (a) boys who have Down syndrome (DS) and (b) typically developing (TD) boys...
- Research review: reading comprehension in developmental disorders of language and communicationJessie Ricketts
Centre for Educational Development, Appraisal and Research CEDAR, University of Warwick, Coventry, UK
J Child Psychol Psychiatry 52:1111-23. 2011..Deficits in reading airment (SLI), Down syndrome (DS) and autism spectrum disorders (ASD)...
- Language impairment and psychiatric comorbiditiesNancie Im-Bolter
Department of Psychology, Otonabee College, Trent University, Peterborough, Ontario, Canada K9J 7B8
Pediatr Clin North Am 54:525-42, vii. 2007..This framework emphasizes the mutually influential transactions approach between developmental domains within individuals and their environment. How knowledge can be translated to practice is discussed...
- Do individuals with autism process words in context? Evidence from language-mediated eye-movementsJon Brock
Department of Experimental Psychology, University of Oxford, Oxford, OX1 3UD, UK
Cognition 108:896-904. 2008..Instead, across both groups, the effect of sentence context was reduced in individuals with relatively poor language skills. Implications for the weak central coherence account of autism are discussed...
- Deficits in volitional oculomotor control align with language status in autism spectrum disordersDavid J Kelly
Department of Psychology, Royal Holloway, University of London, UK
Dev Sci 16:56-66. 2013..We extend the putative link between ALI and LI populations to non-language tasks, and highlight the need to account for co-morbidity in understanding the ontogenesis of ASD...
- Higher order language competence and adolescent mental healthNancy J Cohen
Hincks Dellcrest Centre Institute, University of Toronto, 114 Maitland Street, Toronto, Ontario, Canada
J Child Psychol Psychiatry 54:733-44. 2013..The demands on language for social and academic adjustment shift dramatically during adolescence and the ability to understand the nonliteral meaning in language represented by higher order language becomes essential...
- I thought we were good: social cognition, figurative language, and adolescent psychopathologyNancie Im-Bolter
Department of Psychology, Trent University, Peterborough, ON, Canada
J Child Psychol Psychiatry 54:724-32. 2013..This study investigated the contribution of structural and figurative language to social cognitive skills in adolescents who present for mental health services and those who do not...
- Eye-movement patterns are associated with communicative competence in autistic spectrum disordersCourtenay Frazier Norbury
Department of Experimental Psychology, University of Oxford, UK
J Child Psychol Psychiatry 50:834-42. 2009..However, these studies have not distinguished different cognitive phenotypes...
- Sentence comprehension in children with specific language impairment: effects of input rate and phonological working memoryJames Montgomery
School of Hearing, Speech and Language Sciences, Ohio University, Athens, OH 45701, USA
Int J Lang Commun Disord 39:115-33. 2004..That is, a slower input rate presumably requires the listener to store previously processed information for a longer period while new, incoming material is being processed...
- Early gesture predicts language delay in children with pre- or perinatal brain lesionsEve Sauer
Department of Psychology, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
Child Dev 81:528-39. 2010..Gesture was thus an early marker of which children with early unilateral lesions would eventually experience language delay, suggesting that gesture is a promising diagnostic tool for persistent delay...
- Becoming a manual occupation? The construction of a therapy manual for use with language impaired children in mainstream primary schoolsElspeth McCartney
Department of Speech and Language Therapy, University of Strathclyde, Glasgow
Int J Lang Commun Disord 39:135-48. 2004....
- Auditory processing theories of language disorders: past, present, and futureCarol A Miller
The Pennsylvania State University, University Park, PA, USA
Lang Speech Hear Serv Sch 42:309-19. 2011..The purpose of this article is to provide information that will assist readers in understanding and interpreting research literature on the role of auditory processing in communication disorders...
- MRI analysis of an inherited speech and language disorder: structural brain abnormalitiesK E Watkins
Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London Medical School, London, UK
Brain 125:465-78. 2002..These results thus provide further evidence of a relationship between the abnormal development of this nucleus and the impairments in oromotor control and articulation reported in the KE family...
- Development of language in Rett syndromeJ Uchino
Segawa Neurological Clinic for Children, 2-8 Surugadai, Kanda Chiyodaku, 101-0062, Tokyo, Japan
Brain Dev 23:S233-5. 2001..In RTT a delay in the neuronal systems involved in normal speech development was suggested and its severity seemed to depend on the loci of mutation...
- Qualitative aspects of developmental language impairment relate to language and literacy outcome in adulthoodAndrew J O Whitehouse
Department of Experimental Psychology, University of Oxford, Oxford, UK
Int J Lang Commun Disord 44:489-510. 2009..Developmental language disorder is a heterogeneous diagnostic category. Little research has compared the long-term outcomes of children with different subtypes of language impairment...
- Nonword repetition: the relative contributions of phonological short-term memory and phonological representations in children with language and reading impairmentJudith Rispens
aUniversity of Amsterdam, Amsterdam Center for Language and Communication
J Speech Lang Hear Res 55:683-94. 2012..This was evaluated in children with specific language impairment (SLI) and/or reading impairment (RI); it was also studied from a developmental perspective by comparing 2 groups of typically developing (TD) children who differed in age...
- Predicting language development at age 18 months: data from the Norwegian Mother and Child Cohort StudySynnve Schjølberg
Division of Mental Health, Norwegian Institute of Public Health, Oslo, Norway
J Dev Behav Pediatr 32:375-83. 2011..This study investigated predictors of delayed language development at 18 months of age in a large population cohort of Norwegian toddlers...
- Peculiarities in the gestural repertoire: an early marker for Rett syndrome?Peter B Marschik
Institute of Physiology Developmental Physiology and Developmental Neuroscience IN spired, Center for Physiological Medicine, Medical University of Graz, Austria
Res Dev Disabil 33:1715-21. 2012..We conclude that the gestural abilities in girls with RTT appear to remain limited and do not constitute a compensatory mechanism for the verbal language modality...
- Specific language impairment and school outcomes. I: identifying and explaining variability at the end of compulsory educationGina Conti-Ramsden
University of Manchester, Manchester, UK
Int J Lang Commun Disord 44:15-35. 2009..This investigation reports the results of national educational examinations in secondary schooling for young people who have been participating in the Manchester Language Study...
- Educational and interpersonal uses of home computers by adolescents with and without specific language impairmentKevin Durkin
Department of Psychology, University of Strathclyde, Glasgow, UK
Br J Dev Psychol 27:197-217. 2009..The findings show that language ability contributes to new media use and that adolescents with SLI are at a greater risk of low levels of engagement with educational technology...
- Development and disadvantage: implications for the early years and beyondAnn Locke
Department of Human Communication Sciences, University of Sheffield, 31 Claremont Crescent, Sheffield S10 2TA, UK
Int J Lang Commun Disord 37:3-15. 2002..Government initiatives to raise awareness of spoken language in the early years are discussed, and implications for the future role of speech and language therapists working in the pre-school sector are considered...
- Outcomes of population based language promotion for slow to talk toddlers at ages 2 and 3 years: Let's Learn Language cluster randomised controlled trialMelissa Wake
Royal Children s Hospital, Murdoch Childrens Research Institute, University of Melbourne, Parkville, Vic, Australia
BMJ 343:d4741. 2011..To determine the benefits of a low intensity parent-toddler language promotion programme delivered to toddlers identified as slow to talk on screening in universal services...
- Abnormal functional lateralization and activity of language brain areas in typical specific language impairment (developmental dysphasia)Clément de Guibert
INRIA, VisAGeS Unit Project, F 35042 Rennes, France
Brain 134:3044-58. 2011..This study thus provides evidence that this subtype of specific language impairment is associated with atypical lateralization and functioning of core language areas...
- Spatio-visual memory of children with specific language impairment: evidence for generalized processing problemsEdith L Bavin
School of Psychological Science, La Trobe University, Victoria, Australia
Int J Lang Commun Disord 40:319-32. 2005..Children with Specific language Impairment (SLI) have problems with verbal memory, particularly with tasks that have more processing demands. They also have slower speeds of responding for some tasks...
- Exploring the outcomes of a novel computer-assisted treatment program targeting expressive-grammar deficits in preschoolers with SLIKarla N Washington
Child Language Laboratories, School of Communication Sciences and Disorders, The University of Western Ontario, London, Ontario, Canada
J Commun Disord 44:315-30. 2011..This program was specifically designed with features to directly address expressive-grammar difficulties, thought to be associated with hypothesized deficits in verbal working memory (VWM)...
- The association between expressive grammar intervention and social and emergent literacy outcomes for preschoolers with SLIKarla N Washington
University of Western Ontario, London, Ontario, Canada
Am J Speech Lang Pathol 22:113-25. 2013....
- Interaction before conflict and conflict resolution in pre-school boys with language impairmentLaura Horowitz
Department of Woman and Child Health, Child and Adolescence Psychiatric Unit, Unit for Development and Evaluation, Karolinska Institutet, Stockholm, Sweden
Int J Lang Commun Disord 41:441-66. 2006..The factors involved in peer-conflict progression in pre-school children with LI, and which of these processes may differ from pre-school children with typical language development (TL), is therefore examined...
- Profiling early socio-communicative development in five young girls with the preserved speech variant of Rett syndromePeter B Marschik
Institute of Physiology Developmental Physiology and Developmental Neuroscience IN spired, Center for Physiological Medicine, Medical University of Graz, Austria
Res Dev Disabil 33:1749-56. 2012..We conclude that, even among children with the preserved speech variant, socio-communicative deficits are present before regression and persist after this period...
- Children who read words accurately despite language impairment: who are they and how do they do it?Dorothy V M Bishop
University of Oxford, UK
Child Dev 80:593-605. 2009..Poor language need not hinder acquisition of decoding, so long as rapid serial naming is intact; reading comprehension, however, is constrained by LI...
- Problems and limitations in studies on screening for language delayMårten Eriksson
Department of Social Work and Psychology, Faculty of Health and Occupational Studies, University of Gavle, Gavle, Sweden
Res Dev Disabil 31:943-50. 2010....
- The feasibility of universal screening for primary speech and language delay: findings from a systematic review of the literatureJ Law
Department of Language and Communication Science, City University, London, UK
Dev Med Child Neurol 42:190-200. 2000..This paper discusses the type of data that would be needed to address this issue further and recommendations are made for alternative approaches to early identification...
- Localization of white matter volume increase in autism and developmental language disorderMartha R Herbert
Center for Morphometric Analysis, Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA
Ann Neurol 55:530-40. 2004....
- Evidence of deficient central speech processing in children with specific language impairment: the T-complexValerie L Shafer
The Graduate Center, City University of New York, NY 10016, USA
Clin Neurophysiol 122:1137-55. 2011..This paper examined neurophysiological correlates of speech in children with language impairment (LI) and typical language development (TLD) across four experiments using different speech stimuli and tasks...
- Language skills at age 6 years in Swedish children screened for language delay at 2(1/2) years of ageCarmela Miniscalco
Central Unit for Child Health Care, Department of Women s and Children s Health, Uppsala University Children s Hospital, Uppsala, Sweden
Acta Paediatr 94:1798-806. 2005..The vulnerability that was identified at 2(1/2) y of age, such as problems with going from single-word utterances to multi-word utterances, seems to persist as delayed development at different language levels and across language domains...
- Assessing component language deficits in the early detection of reading difficulty riskHeather K J van der Lely
Department of Psychology, Harvard University, Cambridge, MA 02138, USA
J Learn Disabil 43:357-68. 2010..The article reports on a screening test of these language abilities for preschool or young school-aged children that identifies those at risk for literacy problems and in need of further assessment...
- Non-word repetition: an investigation of phonological complexity in children with Grammatical SLINichola Gallon
Centre for Developmental Language Disorders and Cognitive Neuroscience, Department of Human Communication Science, University College London, UK
Clin Linguist Phon 21:435-55. 2007..The study highlights the importance of taking into account prosodic complexity in phonological assessment and the design of non-word repetition procedures...
- Age 17 language and reading outcomes in late-talking toddlers: support for a dimensional perspective on language delayLeslie Rescorla
Department of Psychology, Bryn Mawr College, 101 North Merion Avenue, Bryn Mawr, PA 19010, USA
J Speech Lang Hear Res 52:16-30. 2009..This study examined whether late talkers identified at 24-31 months continued to have weaker language and reading skills at 17 years of age than typically developing peers...
- Educational attainments of school leavers with a preschool history of speech-language impairmentsM J Snowling
Department of Psychology, Heslington Road, University of York, York YO10 5DD, UK
Int J Lang Commun Disord 36:173-83. 2001....
- Development of the Grammar and Phonology Screening (GAPS) test to assess key markers of specific language and literacy difficulties in young childrenHilary Gardner
Department of Human Communication Sciences, University of Sheffield, Sheffield, UK
Int J Lang Commun Disord 41:513-40. 2006..The Grammar and Phonology Screening (GAPS) test was therefore designed as a short, reliable assessment of young children's language abilities...
- Differential treatment intensity research: a missing link to creating optimally effective communication interventionsSteven F Warren
Institute for Life Span Studies, University of Kansas, Lawrence, Kansas 66045 7555, USA
Ment Retard Dev Disabil Res Rev 13:70-7. 2007..We conclude with three recommendations for the field...
- Collaboration on Specific Language ImpairmentJAMES TOMBLIN; Fiscal Year: 2005..abstract_text> ..
- Predicting Bilirubin-induced Auditory Toxicity in Infants with Severe JaundiceSanjiv B Amin; Fiscal Year: 2010....
- Multiple roles of inhibition in temporal coding of sensory informationAriel Lyons-Warren; Fiscal Year: 2012..The experiments in this proposal will provide critical insight into the diverse roles of inhibition in temporal coding, thus leading to an improved understanding of neural processing of auditory information. ..
- Synaptic mechanisms of temporal pattern recognitionChrista A Baker; Fiscal Year: 2012..A thorough knowledge of how intact neural pathways perform operations critical for sensory perception is vital to research that seeks to identify the underlying causes o complex human disorders. ..
- MORPHOLOGICAL DEFICITS IN SPECIFIC LANGUAGE IMPAIRMENTLaurence Leonard; Fiscal Year: 2007..Such a finding could lead to a uniform theory of how language impairment might develop and persist among children acquiring English. ..
- GRAMMATICAL MORPHOLOGY IN SPECIFIC LANGUAGE IMPAIRMENTLaurence Leonard; Fiscal Year: 2004..abstract_text> ..
- The Genetics of Specific Language ImpairmentJAMES TOMBLIN; Fiscal Year: 2009..The phenotypes and endophenotypes from these individuals will then be used in conjunction with the existing genotyping for additional genome-wide screens and further follow-up fine mapping studies. ..
- Maternal Emotional Well-Being and Fragile X SyndromeLeonard Abbeduto; Fiscal Year: 2006....
- THOUGHT DISORDER: A DEVELOPMENTAL DISABILITY IN EPILEPSYRochelle Caplan; Fiscal Year: 2003..Weekly seizure frequency data will be obtained on a monthly basis from the parent during the 2 years. ..
- Pediatric Thought Disorder: Insights from NeuroimagingRochelle Caplan; Fiscal Year: 2006..abstract_text> ..
- Psycholinguistic and Socioemotional Profiling of SLI and ADHDSean Redmond; Fiscal Year: 2008..Given the academic and social risks associated with misdiagnosis and the poor prognosis associated with untreated comorbidity, this research impacts upon several key public health concerns. [unreadable] [unreadable] [unreadable]..
- WORD LEARNING IN INFANTS WITH HEARING LOSSMary Pat Moeller; Fiscal Year: 2008..The outcomes should provide direction for early interventionists in their efforts to promote nurturing caregiver-child interactions. [unreadable] [unreadable]..
- RESOURCES FOR INFANTS WITH NEWLY IDENTIFIED HEARING LOSSMary Pat Moeller; Fiscal Year: 2006..Information also will be re-purposed and expanded to meet the needs of the target professional audiences. The results of this effort should promote parent self-advocacy and independence in decision making. [unreadable] [unreadable]..
- Social and Affective Processes in AutismHelen Tager Flusberg; Fiscal Year: 2007....
- Effects of Fast ForWord on Language ProcessingMarc Fey; Fiscal Year: 2006..unreadable] [unreadable]..
- DISCRIMINATING SLI AND APD IN SCHOOL-AGE CHILDRENCarol Miller; Fiscal Year: 2007..The results will form the foundation for further research employing larger, more stringently selected samples and both behavioral and electrophysiological measures. ..
- Infants at Risk for Autism Spectrum Disorders or Language DelayHelen Tager Flusberg; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- The impact of inhibition control on working memory in children with SLIKlara Marton; Fiscal Year: 2007..Inhibition control may underlie many of those difficulties that children with SLI experience in everyday learning situations. [unreadable] [unreadable] [unreadable]..
- Language in Autism: Clinical and Basic StudiesHelen Tager Flusberg; Fiscal Year: 2006..These projects will be coordinated by a clinical and administrative core. ..
- Multimodal Neuroimaging of White Matter in AutismMartha Herbert; Fiscal Year: 2009..Our study design will also detect alternate outcomes and will yield data relevant for multiple levels of translational research. ..
- RESOURCES FOR INFANTS WITH NEWLY INDENTIFIED HEARING LOSMary Pat Moeller; Fiscal Year: 2002..A media advocacy program will also be implemented. The results should promote parental self-advocacy and independence in decision making. ..
- AUTISM--BRAIN MORPHOMETRY AND COGNITIVE NEUROSCIENCEMartha Herbert; Fiscal Year: 2003..The nature of developmental dysregulation and neural systems abnormalities in this disorder should thus become clearer. ..
- EARLY IDENTIFICATION OF RISK FOR LANGUAGE DISORDERDonna Thal; Fiscal Year: 2004..abstract_text> ..
- SOCIAL COGNITION IN WILLIAMS SYNDROMEHELEN B TAGER FLUSBERG; Fiscal Year: 2010..This research program will not only advance our understanding of WS;it has the potential to influence developing theoretical models in the growing field of social cognitive neuroscience. ..
- Working memory capacity in children with SLIKlara Marton; Fiscal Year: 2004....
- Effects of Intensity of Early Communication InterventionSTEVEN WARREN; Fiscal Year: 2009..Analyses will include t-tests, 2x2 ANOVA, and multi-level analysis (HLM). Multiple regression or ANCOVA will be used if statistical control of pre-treatment differences are necessary. Five years of funding is requested. ..
- THE DEVELOPMENT OF JOINT ATTENTION AFTER INFANCYLAUREN ADAMSON; Fiscal Year: 2007..Parent actions during social interactions will be described to determine if they too changed during this time interval and whether changes in parent actions predict language outcome at 42 months of age. ..
- Early Language Development Within the Autism SpectrumSusan Ellis Weismer; Fiscal Year: 2010....
- Reward System Recovery Following Behavioral Activation Therapy in DepressionGABRIEL DICHTER; Fiscal Year: 2007..Such a strategy is consistent with NIMH's mission to reduce the burden of psychiatric disorders. [unreadable] [unreadable] [unreadable]..
- Diagnostic Markers of Language Impairment in BilingualsELIZABETH D PENA; Fiscal Year: 2010..abstract_text> ..
- fMRI and DTI in Children with PVH/PVLHeidi M Feldman; Fiscal Year: 2010..It will also contribute to understanding the impact of white matter injury and the development of cortical plasticity after early brain injuries. ..
- Treatment of Speech Disorders in Children with Down SyndromeStephen Camarata; Fiscal Year: 2009..This project is designed to develop more effective treatments for speech disorders in DS. ..
- ERP & Behavioral Predictors of Language InterventionPaul Yoder; Fiscal Year: 2008..Multiple regression, multivariate permutation tests, and growth curve analyses will be used to test the research questions. Five years of funding are requested. ..
- Complex Syntax Production of Children with SLIC Schuele; Fiscal Year: 2008..abstract_text> ..
- Treatment of Lexical Deficits in Young Children with SLISHELLEY I GRAY; Fiscal Year: 2010..abstract_text> ..
- Genetic Bases of Developmental Language DisordersElena L Grigorenko; Fiscal Year: 2010..abstract_text> ..
- Phenotype Assessment Tools:Bilingual(Spanish-English)ELIZABETH PENA; Fiscal Year: 2008..This application addresses this concern by working to develop an assessment protocol to improve identification of bilingual children with language impairment. [unreadable] [unreadable]..
- NEUROBIOLOGIC ORIGINS AND INNOVATIVE TREATMENT OF AUTISMRebecca Landa; Fiscal Year: 2007..Taken as a whole, the projects should add significantly to our knowledge of the ontogeny of autism and thereby lead to the development of novel treatment approaches. ..
- Problems and Competence under Age5: School TransitionAlice Carter; Fiscal Year: 2005....
- Vocal-Motor and Speech-Gesture Coordinations in InfancyJana Iverson; Fiscal Year: 2006..Identification of the typical pattern and normal range of variation in early vocal-manual coordination will provide normative information required for future diagnostic research. ..
- EARLY COMMUNICATION INTERVENTION IN AUTISTIC CHILDRENPaul Yoder; Fiscal Year: 2004..Assessments of communication, vocabulary, and motor imitation will occur at the pre-treatment, port-treatment, and 6 month follow-up periods. Examiners and coders will be blind to treatment assignment. ..
- Cognitive-linguistic processing in L1 and L2Kathryn Kohnert; Fiscal Year: 2004..This explicit theoretical processing model of language learning by L2 learners with and without LI is needed in order to develop clinical measures which can be used to identify LI in the highly variable population of L2 learners. ..
- AUGMENTED LANGUAGE INTERVENTION FOR TODDLERSMARYANN ROMSKI; Fiscal Year: 2004..Findings will advance knowledge about the role of augmented language systems early in life and facilitate the children's adaptive behavior, educational placement, and long-term integration into society. ..
- INFANT PERCEPTUAL ABILITIES AS COGNITIVE PRECURSORSApril Benasich; Fiscal Year: 2003..abstract_text> ..
- Eye-Tracking Studies of Social Visual Pursuit in AutismAmi Klin; Fiscal Year: 2006..The proposed R01 works synergistically with other ongoing eye-tracking research including studies of toddlers at risk of having autism and studies of monkeys with mesiofrontal-limbic ablations. ..
- Childhood Bilingualism & Developmental PsychopathologyCLAUDIO TOPPELBERG; Fiscal Year: 2006..The ultimate goal is to create a solid, leading, lifelong program of research in the fields of Childhood Bilingualism and Developmental Psychopathology. ..
- Grammatical /Intelligibility Intervention--Down SyndromeStephen Camarata; Fiscal Year: 2003..A total of 12 children will be included in a multiple baseline, multiple probe design during the two year project. ..
- LEXICAL DEFICIT--YOUNG CHILD W/ SPECIFIC LANG IMPAIRMENTShelley Gray; Fiscal Year: 2002..abstract_text> ..
- NEURODEVELOPMENTAL OUTCOME OF IN UTERO COCAINE EXPOSUREEmmalee Bandstra; Fiscal Year: 2006..AIM 3: To estimate the ameliorating or exacerbating effects of the caregiving, family, and community environment on neuropsychological, educational, and emotional/behavioral outcomes, and onset of high risk behaviors. ..
- IDENTIFICATION OF GENES INFLUENCING DYSLEXIAShelley Smith; Fiscal Year: 2001..Linkage and association analysis will be used to verify that a candidate gene effects reading disability in the 175 nuclear families. ..
- The Development of Word MeaningKARLA MCGREGOR; Fiscal Year: 2007..It will also reveal sources of lexical deficits associated with SLI and autism, impairments affecting 7% and .3% of the U.S. population, respectively. ..
- Social Behavior of Young Children with Williams SyndromeBONITA KLEIN TASMAN; Fiscal Year: 2004....
- THE MENTAL LEXICON IN LANGUAGE ACQUISITIONHOLLY STORKEL; Fiscal Year: 2005..The findings to emerge hold potential for theories of word learning and the relationship between perception and production in language acquisition. ..
- Reading disability QTLs: pooled DNA on microarraysRobert Plomin; Fiscal Year: 2008..Identifying genes associated with reading disability will eventually lead to better diagnoses, individually tailored treatments, and interventions that can prevent the development of reading disability. ..
- Lateral Asymmetry in the Human Auditory SystemYvonne S Sininger; Fiscal Year: 2010..This project will help to reveal the true nature of the disability imparted to individuals with unilateral deafness and how such disability relates to the side of the deafness. ..
- The Mental Lexicon of Children with Phonological DelaysHOLLY STORKEL; Fiscal Year: 2006..abstract_text> ..
- MULTISITE PREVENTION OF ADOLESCENT CONDUCT PROBLEMSKaren Bierman; Fiscal Year: 2007..abstract_text> ..
- 3 Tesla Magnetic Resonance Imaging for Studies of Child Development and DisordersScott Holland; Fiscal Year: 2008..Installation of modern imaging facilities at CCHMC represents and excellent investment of NCRR resources and is likely to have the greatest possible impact on improving child health. [unreadable] [unreadable] [unreadable]..
- Measuring Active Vision in Toddlers and Young ChildrenLinda Smith; Fiscal Year: 2008..for studying their cascading consequences in social, cognitive and linguistic development, and for developing new therapies and interventions that generalize to the complex natural environment [unreadable] [unreadable] [unreadable]..
- AUDITORY DEVELOPMENT IN EARLY-AMPLIFIED CHILDRENYvonne Sininger; Fiscal Year: 2004....
- Definition and Development of the Phenotype of AutismSally Rogers; Fiscal Year: 2006....
- Early Childhood Education and School Readiness PlanningKaren Bierman; Fiscal Year: 2002..abstract_text> ..
- RESEARCH IN AUTISM: PARENT INTERVENTIONROBERT KOEGEL; Fiscal Year: 2007..In addition, parent satisfaction and stress measures will be gathered in order to assess the effects of each intervention on family functioning. [unreadable] [unreadable]..
- Neurodevelopment and HIV/AIDSAnnelies Van Rie; Fiscal Year: 2005....
- Bilirubin-induced Auditory Neuropathy in PretermsSANJIV AMIN; Fiscal Year: 2008..abstract_text> ..
- 2008 Conference on Cell Replacement in the Inner EarGEORGE GATES; Fiscal Year: 2008..This interchange should invigorate and focus research in inner ear hearing regeneration. [unreadable] [unreadable] [unreadable]..
- Deafness Research Foundation Clinical Research WorkshopGEORGE GATES; Fiscal Year: 2005..Attendees will be physicians and clinicians in communication disorders, such as audiologists and speech/language pathologists. Fellowships will be available for attendees. ..
- Attentional Control in Preschoolers With and Without SLITAMMIE SPAULDING; Fiscal Year: 2007..Furthermore, the methodology proposed has the potential to offer improved procedures for diagnosing attentional difficulties at an early age, regardless of language status. [unreadable] [unreadable] [unreadable]..
- Deafness Research Foundation Clinical Research WorkshopGEORGE GATES; Fiscal Year: 2004..Attendees will be physicians and clinicians in communication disorders, such as audiologists and speech/language pathologists. Fellowships will be available for attendees. ..