goals

Summary

Summary: The end-result or objective, which may be specified or required in advance.

Top Publications

  1. pmc Human and rodent homologies in action control: corticostriatal determinants of goal-directed and habitual action
    Bernard W Balleine
    Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
    Neuropsychopharmacology 35:48-69. 2010
  2. doi HIV-related stigma as a barrier to achievement of global PMTCT and maternal health goals: a review of the evidence
    Janet M Turan
    Department of Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA
    AIDS Behav 17:2528-39. 2013
  3. doi The unconscious will: how the pursuit of goals operates outside of conscious awareness
    Ruud Custers
    Department of Psychology, Utrecht University, Heidelberglaan 1, 3584 CS Utrecht, Netherlands
    Science 329:47-50. 2010
  4. ncbi Infants predict other people's action goals
    Terje Falck-Ytter
    Department of Psychology, Uppsala University, Box 1225, 751 42 Uppsala, Sweden
    Nat Neurosci 9:878-9. 2006
  5. ncbi Parietal lobe: from action organization to intention understanding
    Leonardo Fogassi
    Dipartimento di Psicologia, Universita di Parma, Borgo Carissimi 10, 43100 Parma, Italy
    Science 308:662-7. 2005
  6. pmc Hippocampal place-cell sequences depict future paths to remembered goals
    Brad E Pfeiffer
    Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nature 497:74-9. 2013
  7. doi Learner regulated knowledge of results during the acquisition of multiple timing goals
    Jae T Patterson
    Department of Physical Education and Kinesiology, Brock University, Canada
    Hum Mov Sci 29:214-27. 2010
  8. ncbi Building a practically useful theory of goal setting and task motivation. A 35-year odyssey
    Edwin A Locke
    R H Smith School of Business, University of Maryland, USA
    Am Psychol 57:705-17. 2002
  9. pmc Goals and habits in the brain
    Ray J Dolan
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1 3BG, UK Electronic address
    Neuron 80:312-25. 2013
  10. pmc The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988-2010
    Sarah Stark Casagrande
    Social and Scientific Systems, Inc, Silver Spring, Maryland, USA
    Diabetes Care 36:2271-9. 2013

Detail Information

Publications324 found, 100 shown here

  1. pmc Human and rodent homologies in action control: corticostriatal determinants of goal-directed and habitual action
    Bernard W Balleine
    Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
    Neuropsychopharmacology 35:48-69. 2010
    ..The neural basis of the integration of learning and motivation in choice and decision-making is still controversial and we review some recent hypotheses relating to this issue...
  2. doi HIV-related stigma as a barrier to achievement of global PMTCT and maternal health goals: a review of the evidence
    Janet M Turan
    Department of Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA
    AIDS Behav 17:2528-39. 2013
    The global community has set goals of virtual elimination of new child HIV infections and 50 percent reduction in HIV-related maternal mortality by the year 2015...
  3. doi The unconscious will: how the pursuit of goals operates outside of conscious awareness
    Ruud Custers
    Department of Psychology, Utrecht University, Heidelberglaan 1, 3584 CS Utrecht, Netherlands
    Science 329:47-50. 2010
    People often act in order to realize desired outcomes, or goals. Although behavioral science recognizes that people can skillfully pursue goals without consciously attending to their behavior once these goals are set, conscious will is ..
  4. ncbi Infants predict other people's action goals
    Terje Falck-Ytter
    Department of Psychology, Uppsala University, Box 1225, 751 42 Uppsala, Sweden
    Nat Neurosci 9:878-9. 2006
    ..The activation of this system requires observing an interaction between the hand of the agent and an object...
  5. ncbi Parietal lobe: from action organization to intention understanding
    Leonardo Fogassi
    Dipartimento di Psicologia, Universita di Parma, Borgo Carissimi 10, 43100 Parma, Italy
    Science 308:662-7. 2005
    ..Thus, these neurons not only code the observed motor act but also allow the observer to understand the agent's intentions...
  6. pmc Hippocampal place-cell sequences depict future paths to remembered goals
    Brad E Pfeiffer
    Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nature 497:74-9. 2013
    ....
  7. doi Learner regulated knowledge of results during the acquisition of multiple timing goals
    Jae T Patterson
    Department of Physical Education and Kinesiology, Brock University, Canada
    Hum Mov Sci 29:214-27. 2010
    ..Thus, the results extend previous research by suggesting a generalized learning strategy by performers acquiring multiple motor task goals.
  8. ncbi Building a practically useful theory of goal setting and task motivation. A 35-year odyssey
    Edwin A Locke
    R H Smith School of Business, University of Maryland, USA
    Am Psychol 57:705-17. 2002
    ..They describe the core findings of the theory, the mechanisms by which goals operate, moderators of goal effects, the relation of goals and satisfaction, and the role of goals as mediators of ..
  9. pmc Goals and habits in the brain
    Ray J Dolan
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1 3BG, UK Electronic address
    Neuron 80:312-25. 2013
    ..We review four generations of work in this tradition and provide pointers to the forefront of the field's fifth generation. ..
  10. pmc The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988-2010
    Sarah Stark Casagrande
    Social and Scientific Systems, Inc, Silver Spring, Maryland, USA
    Diabetes Care 36:2271-9. 2013
    ..who meet hemoglobin A1c (A1C), blood pressure (BP), and LDL cholesterol (ABC) recommendations and their current statin use, factors associated with goal achievement, and changes in the proportion achieving goals between 1988 and 2010.
  11. ncbi Therapeutic inertia is an impediment to achieving the Healthy People 2010 blood pressure control goals
    Eni C Okonofua
    Medical University of South Carolina, Charleston, SC 29425, USA
    Hypertension 47:345-51. 2006
    Therapeutic inertia (TI), defined as the providers' failure to increase therapy when treatment goals are unmet, contributes to the high prevalence of uncontrolled hypertension (> or =140/90 mm Hg), but the quantitative impact is ..
  12. ncbi Determining the neural substrates of goal-directed learning in the human brain
    Vivian V Valentin
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 27:4019-26. 2007
    ..These results suggest an important contribution of orbitofrontal cortex in guiding goal-directed instrumental choices in humans...
  13. doi Understanding others' actions and goals by mirror and mentalizing systems: a meta-analysis
    Frank Van Overwalle
    Vrije Universiteit Brussel, Belgium
    Neuroimage 48:564-84. 2009
    ..explores the role of the mirror and mentalizing systems in the understanding of other people's action goals. Based on over 200 fMRI studies, this analysis demonstrates that the mirror system - consisting of the anterior ..
  14. ncbi Husbands' versus wives' fertility goals and use of contraception: the influence of gender context in five Asian countries
    K O Mason
    World Bank, Washington, DC 20433, USA
    Demography 37:299-311. 2000
    ..This is the case because the proportion of couples with differing fertility goals is small in most communities.
  15. ncbi Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI, 48109 0720, USA
    Psychopharmacology (Berl) 191:599-607. 2007
    ..The way an individual responds to cues associated with rewards may be a key determinant of vulnerability to compulsive behavioral disorders...
  16. pmc Optimizing the decoding of movement goals from local field potentials in macaque cortex
    David A Markowitz
    Center for Neural Science, New York University, New York, New York 10003, USA
    J Neurosci 31:18412-22. 2011
    ..implanted multielectrode arrays with individually movable electrodes to examine how the encoding of movement goals depends on cortical depth...
  17. pmc Report on the inaugural meeting of the International Consortium on Hallucination Research: a clinical and research update and 16 consensus-set goals for future research
    Flavie Waters
    Centre for Clinical Research in Neuropsychiatry, Graylands Hospital, Mail Bag No 1, Claremont, Perth 6910, Western Australia
    Schizophr Bull 38:258-62. 2012
    ..Here, we outline the top 16 goals for research on auditory hallucinations, which cover topics of conceptual importance, academic and treatment ..
  18. pmc Calculating consequences: brain systems that encode the causal effects of actions
    Saori C Tanaka
    Division of the Humanities and Social Sciences and Computation and Neural Systems Program, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 28:6750-5. 2008
    ..These results reveal the involvement of distinct brain regions in the computational processes that establish the causal efficacy of actions, providing insight into the neural mechanisms underlying the adaptive control of behavior...
  19. pmc Achieving the Millennium Development Goals: does mental health play a role?
    J Jaime Miranda
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS Med 2:e291. 2005
  20. doi Orienting attention in time activates left intraparietal sulcus for both perceptual and motor task goals
    Karen Davranche
    Université de Provence and Centre National de la Recherche Scientifique, Marseille Cedex 3, France
    J Cogn Neurosci 23:3318-30. 2011
    ....
  21. pmc Action experience alters 3-month-old infants' perception of others' actions
    Jessica A Sommerville
    Department of Psychology and Institute for Learning and Brain Sciences, University of Washington, Seattle, Washington 98195, USA
    Cognition 96:B1-11. 2005
    ..These findings indicate that infants can rapidly form goal-based action representations and suggest a developmental link between infants' goal directed actions and their ability to detect goals in the actions of others.
  22. doi Are we on course for reporting on the Millennium Development Goals in 2015?
    Deborah Rugg
    Department of Evidence, Monitoring and Policy EMP, Monitoring and Evaluation EVA Division, UNAIDS, Geneva, Switzerland
    J Acquir Immune Defic Syndr 52:S69-76. 2009
    ....
  23. doi Interactions between health technology assessment, coverage, and regulatory processes: emerging issues, goals, and opportunities
    Chris Henshall
    University of York and Health Technology Assessment International
    Int J Technol Assess Health Care 27:253-60. 2011
    ..This study summarizes the main points emerging from a recent discussion of this topic at the HTAi Policy Forum...
  24. doi Do patients and providers agree about the most important facts and goals for breast reconstruction decisions?
    Clara N Lee
    Division of Plastic and Reconstructive Surgery, University of North Carolina, Chapel Hill, NC 27599 7195, USA
    Ann Plast Surg 64:563-6. 2010
    ..related to the decision, and the treatment chosen should be consistent with the patient's personal preferences or goals. We sought to identify the most important facts and goals for decisions about breast reconstruction after ..
  25. doi Tracking the construction of episodic future thoughts
    Arnaud D'Argembeau
    Department of Cognitive Sciences, University of Lie ge, Lie ge, Belgium
    J Exp Psychol Gen 140:258-71. 2011
    ..of this general personal knowledge and tested the hypothesis that it is mainly organized in terms of personal goals. Study 2 showed that cuing participants with knowledge about personal goals increased the ease of future event ..
  26. doi Recommended dietary reference intakes, nutritional goals and dietary guidelines for fat and fatty acids: a systematic review
    Javier Aranceta
    Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain
    Br J Nutr 107:S8-22. 2012
    ..are analyzed following a systematic review process to examine dietary reference intakes, nutritional goals and dietary guidelines for fat and fatty acids...
  27. doi Triangles have goals too: understanding action representation in left aIPS
    Richard Ramsey
    School of Psychology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Neuropsychologia 48:2773-6. 2010
    ..However, it is not yet known if the brain systems that respond to human action-goals also respond to the action-goals of shapes...
  28. pmc Nine-months-old infants do not need to know what the agent prefers in order to reason about its goals: on the role of preference and persistence in infants' goal-attribution
    Mikolaj Hernik
    Research Department of Educational, Clinical and Health Psychology, University College London, UK
    Dev Sci 15:714-22. 2012
    Human infants readily interpret others' actions as goal-directed and their understanding of previous goals shapes their expectations about an agent's future goal-directed behavior in a changed situation...
  29. doi The essential tension between leadership and power: when leaders sacrifice group goals for the sake of self-interest
    Jon K Maner
    Department of Psychology, Florida State University, FL, USA
    J Pers Soc Psychol 99:482-97. 2010
    Throughout human history, leaders have been responsible for helping groups attain important goals. Ideally, leaders use their power to steer groups toward desired outcomes...
  30. doi Habitual versus goal-directed action control in Parkinson disease
    Sanne de Wit
    Department of Psychology, Amsterdam Center for Study of Adaptive Control in Brain and Behavior Acacia, University of Amsterdam, Roeterstraat 15, 1018 WB, The Netherlands
    J Cogn Neurosci 23:1218-29. 2011
    ..If anything our results suggest a disease severity-dependent deficit in goal-directed behavior. These results are discussed in the context of Parkinson disease and the neurobiology of habitual and goal-directed behavior...
  31. ncbi Goal-selection and movement-related conflict during bimanual reaching movements
    Jorn Diedrichsen
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
    Cereb Cortex 16:1729-38. 2006
    Conflict during bimanual movements can arise during the selection of movement goals or during movement planning and execution. We demonstrate a behavioral and neural dissociation of these 2 types of conflict...
  32. doi Performance goals on simulators boost resident motivation and skills laboratory attendance
    Dimitrios Stefanidis
    Carolinas Simulation Center, Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
    J Surg Educ 67:66-70. 2010
    To assess the impact of setting simulator training goals on resident motivation and skills laboratory attendance.
  33. doi Goal-oriented cognitive rehabilitation for people with early-stage Alzheimer disease: a single-blind randomized controlled trial of clinical efficacy
    Linda Clare
    Bangor University, United Kingdom
    Am J Geriatr Psychiatry 18:928-39. 2010
    ..To provide evidence regarding the clinical efficacy of cognitive rehabilitation (CR) in early-stage Alzheimer disease (AD)...
  34. doi Writing SMART rehabilitation goals and achieving goal attainment scaling: a practical guide
    Thamar J H Bovend'Eerdt
    Oxford Brookes University and Oxford Centre for Enablement, Nuffield Orthopaedic Centre, Oxford, UK
    Clin Rehabil 23:352-61. 2009
    To describe a practical method of setting personalized but specific goals in rehabilitation that also facilitates the use of goal attainment scaling.
  35. ncbi Regret and quality of life across the adult life span: the influence of disengagement and available future goals
    Carsten Wrosch
    Department of Psychology, Centre for Research in Human Development, Concordia University, Montreal, PQ, Canada
    Psychol Aging 20:657-70. 2005
    ..It was suggested that being disengaged from undoing the consequences of regrets and having many future goals available may reduce older adults' intensity of regret and thereby contribute to a better quality of life...
  36. doi Corticostriatal connectivity underlies individual differences in the balance between habitual and goal-directed action control
    Sanne de Wit
    Amsterdam Center for the Study of Adaptive Control in Brain and Behavior, Department of Developmental Psychology, University of Amsterdam, 1018 XA Amsterdam, The Netherlands
    J Neurosci 32:12066-75. 2012
    ..These findings suggest that integrity of dissociable corticostriatal pathways underlies individual differences in action control in the healthy population, which may ultimately mediate vulnerability to impulse control disorders...
  37. ncbi Mechanisms of implementation intention effects: the role of goal intentions, self-efficacy, and accessibility of plan components
    Thomas L Webb
    Department of Psychology, University of Sheffield, Sheffield, UK
    Br J Soc Psychol 47:373-95. 2008
    ..These findings suggest that implementation intention effects are not explained by increased deliberation, but rather accrue from heightened accessibility of specified opportunities and strong opportunity-response links...
  38. ncbi Self-regulation of goal setting: turning free fantasies about the future into binding goals
    G Oettingen
    Department of Psychology, New York University, New York 10003, USA
    J Pers Soc Psychol 80:736-53. 2001
    ..g., making plans), affective (e.g., felt attachment), and behavioral terms (e.g., effort expenditure, quality of performance). Implications for theories on goal setting and goal striving are discussed...
  39. doi Intention, action planning, and decision making in parietal-frontal circuits
    Richard A Andersen
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Neuron 63:568-83. 2009
    ..These sensorimotor functions can be harnessed for neural prosthetic operations by decoding intended goals (planning) and trajectories (forward state estimation) of movements as well as higher cortical functions related ..
  40. pmc Mania and dysregulation in goal pursuit: a review
    Sheri L Johnson
    Flipse Building Fifth Floor, Department of Psychology, University of Miami, 5665 Ponce de Leon Blvd, Coral Gables, FL 33146, USA
    Clin Psychol Rev 25:241-62. 2005
    ..These increases in confidence, coupled with a background of ambitious goals, are believed to promote excessive pursuit of goals...
  41. ncbi Goal setting as a strategy for dietary and physical activity behavior change: a review of the literature
    Mical Kay Shilts
    Family and Consumer Sciences Department, California State University, Sacramento, California, USA
    Am J Health Promot 19:81-93. 2004
    ..Estimate effectiveness of goal setting for nutrition and physical activity behavior change, review the effect of goal-setting characteristics on behavior change, and investigate effectiveness of interventions containing goal setting...
  42. pmc Differential coupling of visual cortex with default or frontal-parietal network based on goals
    James Z Chadick
    Department of Neurology, Physiology and Psychiatry, W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, USA
    Nat Neurosci 14:830-2. 2011
    ..This indicates that sensory cortical regions are differentially and dynamically coupled with distinct networks on the basis of task goals.
  43. doi Motor abstraction: a neuroscientific account of how action goals and intentions are mapped and understood
    Vittorio Gallese
    Department of Neuroscience, Section of Physiology, University of Parma, Parma, Italy
    Psychol Res 73:486-98. 2009
    ..Empirical evidence on the neural underpinnings of action goals and on their ontogeny and phylogeny is introduced and discussed...
  44. ncbi How global versus local perception fits regulatory focus
    Jens Förster
    International University Bremen, Germany
    Psychol Sci 16:631-6. 2005
    ....
  45. doi Goals, attention, and (un)consciousness
    Ap Dijksterhuis
    Behavioral Science Institute, Radboud University Nijmegen, 6500 HE Nijmegen, The Netherlands
    Annu Rev Psychol 61:467-90. 2010
    ..from neuroscience, cognitive psychology, and social cognition is integrated to discuss the relation between goals, attention, and consciousness. Goals are the tools with which people engage in volitional behavior...
  46. doi Motor system activation reveals infants' on-line prediction of others' goals
    Victoria Southgate
    Centre for Brain and Cognitive Development, School of Psychology, Birkbeck, Malet St, London WC1E 7HX, United Kingdom
    Psychol Sci 21:355-9. 2010
    Despite much research demonstrating infants' abilities to attribute goals to others' actions, it is unclear whether infants can generate on-line predictions about action outcomes, an ability crucial for the human propensity to cooperate ..
  47. pmc Differential engagement of the ventromedial prefrontal cortex by goal-directed and habitual behavior toward food pictures in humans
    Sanne de Wit
    Amsterdam Center for the Study of Adaptive Control in Brain and Behavior Acacia, Department of Psychology, University of Amsterdam, 1018 WB Amsterdam, The Netherlands
    J Neurosci 29:11330-8. 2009
    ..We can therefore exclude a purely Pavlovian account of ventromedial prefrontal function and unequivocally demonstrate its involvement in the acquisition as well as deployment of goal-directed knowledge...
  48. ncbi Intelligence and the frontal lobe: the organization of goal-directed behavior
    J Duncan
    MRC Applied Psychology Unit, Cambridge, United Kingdom
    Cogn Psychol 30:257-303. 1996
    ..A frontal process of constraint or requirement activation is fundamental to Spearman's g...
  49. pmc Beyond grasping: representation of action in human anterior intraparietal sulcus
    E Tunik
    Department of Physical Therapy, Steinhardt School of Education, New York University, NY, USA
    Neuroimage 36:T77-86. 2007
    ..a network involved in the higher order dynamic control of action, including representation of intended action goals. These findings may be important not only for guiding the design of future experiments investigating related ..
  50. ncbi Palliative goals, patient selection, and perioperative platelet management: outcomes and lessons from 3 decades of splenectomy for myelofibrosis with myeloid metaplasia at the Mayo Clinic
    Ruben A Mesa
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 107:361-70. 2006
    ..The authors retrospectively analyzed their experience with splenectomy over the course of 30 years to analyze the impact of improved techniques, antimicrobials, and aggressive postoperative control of platelet counts on outcome...
  51. doi Using immunization delivery strategies to accelerate progress in Africa towards achieving the Millennium Development Goals
    C John Clements
    Centre for International Health, The Macfarlane Burnet Institute for Medical Research and Public Health Ltd, GPO Box 2284, Commercial Road, Melbourne, VIC 3004, Australia
    Vaccine 26:1926-33. 2008
    ..within and between organizations to solve common problems, developing a commitment to a shared vision and goals, and using common technologies and resources to achieve these goals...
  52. ncbi Goal neglect and inhibitory limitations: dissociable causes of interference effects in conflict situations
    R De Jong
    Institute of Experimental and Occupational Psychology, University of Groningen, The Netherlands
    Acta Psychol (Amst) 101:379-94. 1999
    ..These results indicate that, in addition to mean performance levels, variability of task performance may provide a valuable source of evidence regarding the actual cause of performance limitations or deficits in conflict situations...
  53. pmc A navigational guidance system in the human brain
    Hugo J Spiers
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1N 3BG, United Kingdom
    Hippocampus 17:618-26. 2007
    ..current position during navigation, surprisingly little is known about how the human brain guides navigation to goals. Computational accounts argue that specific brain regions support navigational guidance by coding the proximity ..
  54. ncbi Neuronal correlates of goal-based motor selection in the prefrontal cortex
    Kenji Matsumoto
    Cognitive Brain Mapping Laboratory, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Science 301:229-32. 2003
    ..This prefrontal activity is likely to underlie goal-based action selection...
  55. pmc Shift from goal-directed to habitual cocaine seeking after prolonged experience in rats
    Agustin Zapata
    Integrative Neuroscience Section, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Baltimore, Maryland 21224, USA
    J Neurosci 30:15457-63. 2010
    ....
  56. pmc Millennium Development Goals 4 and 5: progress and challenges
    Jennifer Bryce
    Institute for International Programs, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    BMC Med 11:225. 2013
    The Millennium Development Goals have galvanized efforts to improve child survival (MDG-4) and maternal health (MDG-5)...
  57. pmc The unconscious regulation of emotion: nonconscious reappraisal goals modulate emotional reactivity
    Lawrence E Williams
    Leeds School of Business, University of Colorado at Boulder, UCB 419, Boulder, CO 80309, USA
    Emotion 9:847-54. 2009
    ..Two experiments examined the effects of nonconsciously operating goals on people's emotion regulatory success. In Experiment 1, participants engaged in an anxiety-eliciting task...
  58. ncbi Goal-directed training: linking theories of treatment to clinical practice for improved functional activities in daily life
    M Mastos
    School of Occupational Therapy, La Trobe University, Bundoora, Australia
    Clin Rehabil 21:47-55. 2007
    BACKGROUND: Goal-directed training is an activity-based approach to therapy. Meaningful, client-selected goals are used to provide opportunities for problem solving and to indirectly drive the movements required to successfully meet the ..
  59. ncbi Task goals and change in dynamical degrees of freedom with motor learning
    Karl M Newell
    Department of Kinesiology, College of Health and Human Development, Pennsylvania State University, University Park 16802, USA
    J Exp Psychol Hum Percept Perform 29:379-87. 2003
    ..These findings support the proposition that the observed increase or decrease in dimension with learning is dependent on both the intrinsic dynamics of the system and the short-term change required to realize the task goal...
  60. doi Goal-directed aiming: two components but multiple processes
    Digby Elliott
    School of Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, England
    Psychol Bull 136:1023-44. 2010
    ..e., Down syndrome, Williams syndrome, autism spectrum disorder, normal aging) within the framework of a multiple-process approach to goal-directed aiming...
  61. doi Identifying and applying psychological theory to setting and achieving rehabilitation goals
    Lesley Scobbie
    Alliance for Self Care Research, Department of Nursing and Midwifery, University of Stirling, Stirling, Scotland, UK
    Clin Rehabil 23:321-33. 2009
    ..Goal setting is considered to be a fundamental part of rehabilitation; however, theories of behaviour change relevant to goal-setting practice have not been comprehensively reviewed...
  62. pmc Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder
    Claire M Gillan
    Department of Experimental Psychology and Psychiatry, University of Cambridge, Cambridge, UK
    Am J Psychiatry 168:718-26. 2011
    ..This study investigated whether the urge to perform compulsive acts is mediated by a disruption in the balance between flexible, goal-directed action control and habitual behavior...
  63. ncbi The frequency and behavioral outcomes of goal choices in the self-management of diabetes
    Paul A Estabrooks
    Clinical Research Unit, Kaiser Permanente Colorado, Aurora, CO, USA
    Diabetes Educ 31:391-400. 2005
    ..determine the frequency and effectiveness of behavioral goal choices in the self-management of diabetes and to test goal-setting theory hypotheses that self-selection and behavioral specificity of goals are key to enhancing persistence.
  64. pmc Genome Consortium for Active Teaching: meeting the goals of BIO2010
    A Malcolm Campbell
    Department of Biology, Davidson College, Davidson, NC 28035, USA
    CBE Life Sci Educ 6:109-18. 2007
    ..GCAT is meeting important goals of BIO2010 by making research methods accessible to undergraduates, training faculty in genomics and ..
  65. doi Long-term aftereffects of response inhibition: memory retrieval, task goals, and cognitive control
    Frederick Verbruggen
    Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
    J Exp Psychol Hum Percept Perform 34:1229-35. 2008
    ..can slow responses for 1-20 trials after successful inhibition, which suggests the automatic retrieval of task goals. On the basis of these findings, the authors concluded that cognitive control can rely on both memory retrieval ..
  66. pmc Can a self-propelled box have a goal? Psychological reasoning in 5-month-old infants
    Yuyan Luo
    Psychology Department, University of Illinois, Champaign, 61820, USA
    Psychol Sci 16:601-8. 2005
    Some researchers have suggested that infants' ability to reason about goals develops as a result of their experiences with human agents and is then gradually extended to other agents...
  67. doi Stress prompts habit behavior in humans
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 29:7191-8. 2009
    ..Moreover, stress reduced subjects' explicit knowledge of the action-outcome contingencies. These results demonstrate for the first time that stress promotes habits at the expense of goal-directed performance in humans...
  68. ncbi Health, development and the Millennium Development Goals
    R Dodd
    Department for Health Policy, Development and Services, EIP HDS, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
    Ann Trop Med Parasitol 100:379-87. 2006
    The Millennium Development Goals (MDG), which emerged from the United Nations Millennium Summit in 2000, are increasingly recognized as the over-arching development framework...
  69. doi Prebiotics and the health benefits of fiber: current regulatory status, future research, and goals
    Amy M Brownawell
    Life Sciences Research Organization, Inc, Bethesda, MD, USA
    J Nutr 142:962-74. 2012
    ..LSRO) held a workshop, Prebiotics and the Health Benefits of Fiber: Future Research and Goals, in February 2011 to assess the current state of the science and the international regulatory environment for ..
  70. pmc Accounting for water quality in monitoring access to safe drinking-water as part of the Millennium Development Goals: lessons from five countries
    Rob E S Bain
    Water and Health Research Centre, University of Bristol, England
    Bull World Health Organ 90:228-235A. 2012
    ..To determine how data on water source quality affect assessments of progress towards the 2015 Millennium Development Goal (MDG) target on access to safe drinking-water...
  71. pmc Addressing inequity to achieve the maternal and child health millennium development goals: looking beyond averages
    George M Ruhago
    School of Public Health and Social Sciences, Muhimbili University, P, O Box 65015, Dar es Salaam, Tanzania
    BMC Public Health 12:1119. 2012
    ..maternal health interventions is impeding progress towards the maternal and child health Millennium Development Goals. This study explores the potential health gains and equity impact if a set of priority interventions for mothers ..
  72. pmc Pairings of lever and food induce Pavlovian conditioned approach of sign-tracking and goal-tracking in C57BL/6 mice
    Arthur Tomie
    Center of Alcohol Studies, Rutgers The State University of New Jersey, 607 Allison Road, Piscataway, NJ 08854 8001, USA
    Behav Brain Res 226:571-8. 2012
    ..Corticosterone release, a pathophysiological marker of vulnerability to drug abuse, was positively related to ST CR performance...
  73. doi Through the looking glass: focusing on long-term goals increases immanent justice reasoning
    Mitchell J Callan
    Department of Psychology, University of Essex, UK
    Br J Soc Psychol 52:377-85. 2013
    ..moral) behaviour to a greater extent when they first focused on their long-term (vs. short-term) goals. These findings highlight the important function believing in a just world plays in self-regulatory processes by ..
  74. ncbi Management of Wilms' tumour: current practice and future goals
    John A Kalapurakal
    Department of Radiation Oncology, Children s Memorial Hospital, Northwestern University, IL, Chicago, USA
    Lancet Oncol 5:37-46. 2004
    ..Better understanding of the biological processes that lead to this childhood cancer will allow further improvements in its management...
  75. doi Evidence for a unitary goal concept in 12-month-old infants
    Szilvia Biro
    Department of Psychology, Leiden University, The Netherlands
    Dev Sci 14:1255-60. 2011
    ..This finding suggests that, by 12 months, infants possess a unitary concept of goal...
  76. pmc "Let's work together": what do infants understand about collaborative goals?
    Annette M E Henderson
    Department of Psychology, HSB building, 10 Symonds Street, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
    Cognition 121:12-21. 2011
    ..The implications of our findings for theories of collaboration and folk psychology are discussed...
  77. pmc Speed/accuracy trade-off between the habitual and the goal-directed processes
    Mehdi Keramati
    School of Management and Economics, Sharif University of Technology, Tehran, Iran
    PLoS Comput Biol 7:e1002055. 2011
    ....
  78. ncbi Predicting objectively assessed physical activity from the content and regulation of exercise goals: evidence for a mediational model
    Simon J Sebire
    Centre for Exercise, Nutrition and Health Sciences, University of Bristol, Bristol, U K
    J Sport Exerc Psychol 33:175-97. 2011
    ..Ryan, 2000), the purpose of this work was to examine effects of the content and motivation of adults' exercise goals on objectively assessed moderate-to-vigorous physical activity (MVPA)...
  79. pmc Infants generate goal-based action predictions
    Erin N Cannon
    Department of Human Development, University of Maryland, College Park, MD 20742, USA
    Dev Sci 15:292-8. 2012
    ..This study suggests that by 11 months infants actively use goal analysis to generate on-line predictions of an agent's next action...
  80. doi Parallel goal-directed and habitual control of human drug-seeking: implications for dependence vulnerability
    Lee Hogarth
    School of Psychology, University of Nottingham, UK
    J Exp Psychol Anim Behav Process 37:261-76. 2011
    ....
  81. doi Randomized controlled trial of peer-led recovery education using Building Recovery of Individual Dreams and Goals through Education and Support (BRIDGES)
    Judith A Cook
    University of Illinois at Chicago, Department of Psychiatry, Chicago, IL 60612, United States
    Schizophr Res 136:36-42. 2012
    The purpose of this study was to test the efficacy of a peer-led, mental illness education intervention called Building Recovery of Individual Dreams and Goals through Education and Support (BRIDGES).
  82. doi Financing of health systems to achieve the health Millennium Development Goals in low-income countries
    Robert Fryatt
    Health Systems and Services, World Health Organization, Geneva, Switzerland
    Lancet 375:419-26. 2010
    Concern that underfunded and weak health systems are impeding the achievement of the health Millennium Development Goals in low-income countries led to the creation of a High Level Taskforce on Innovative International Financing for ..
  83. doi Goal anticipation during action observation is influenced by synonymous action capabilities, a puzzling developmental study
    Gustaf Gredeback
    Department of Psychology, Uppsala University, Uppsala, Sweden
    Exp Brain Res 202:493-7. 2010
    ..53). These findings suggests a connection between manual ability and the ability to anticipate the goal of others' actions in toddlers, in accordance with the direct matching hypothesis...
  84. pmc The AgeWell study of behavior change to promote health and wellbeing in later life: study protocol for a randomized controlled trial
    Linda Clare
    School of Psychology, Bangor University, Bangor, Gwynedd, LL57 2AS, UK
    Trials 13:115. 2012
    ..Lifestyle factors playing a role in the development of late-life disability may be modifiable. There is a need for robust evidence about the potential for prevention of disability through behavior change interventions...
  85. ncbi The concept and measurement of meaning in life in Dutch cancer patients
    Tessa A Jaarsma
    Northern Centre for Healthcare Research, University Medical Center Groningen, University of Groningen, The Netherlands
    Psychooncology 16:241-8. 2007
    ..Future research can investigate its appropriateness for other populations than cancer patients, and if and how the experience of meaning in life eventually changes as a result of existential threats...
  86. doi Rehabilitation of executive functioning with training in attention regulation applied to individually defined goals: a pilot study bridging theory, assessment, and treatment
    Tatjana Novakovic-Agopian
    Veteran s Administration Medical Center, San Francisco, California 94121, USA
    J Head Trauma Rehabil 26:325-38. 2011
    ..To assess feasibility and effects of training in goal-oriented attentional self-regulation for patients with brain injury and chronic executive dysfunction...
  87. pmc The automated will: nonconscious activation and pursuit of behavioral goals
    J A Bargh
    Department of Psychology, New York University, New York 10003, USA
    J Pers Soc Psychol 81:1014-27. 2001
    It is proposed that goals can be activated outside of awareness and then operate nonconsciously to guide self-regulation effectively (J. A. Bargh, 1990)...
  88. doi Understanding the goals of service learning and community-based medical education: a systematic review
    Justin B Hunt
    Division of Health Services Research, Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Acad Med 86:246-51. 2011
    To understand the educational goals of projects described as "service learning" or "community-based medical education" and to learn how relationships between medical schools and community members are discussed in these projects.
  89. pmc Encoding goals but not abstract magnitude in the primate prefrontal cortex
    Aldo Genovesio
    Department of Physiology and Pharmacology, Sapienza, University of Rome, 00185 Rome, Italy
    Neuron 74:656-62. 2012
    ..result, domain-specific neural processing at the single-cell level seems to underlie domain generality as observed at the regional level, with a common representation of prospective goals rather than a common representation of magnitude.
  90. pmc Chimpanzees' flexible targeted helping based on an understanding of conspecifics' goals
    Shinya Yamamoto
    Primate Research Institute, Kyoto University, Inuyama, Aichi 4848506, Japan
    Proc Natl Acad Sci U S A 109:3588-92. 2012
    ..Many still believe that this is because only humans can understand others' goals due to our unique "theory of mind" abilities, especially shared intentionality...
  91. ncbi Approach-avoidance motivation in personality: approach and avoidance temperaments and goals
    Andrew J Elliot
    Department of Clinical and Social Sciences in Psychology, University of Rochester, New York 14627 0266, USA
    J Pers Soc Psychol 82:804-18. 2002
    ..In Studies 3-7, approach and avoidance temperaments were shown to be systematically linked to achievement goals (both nomothetic and idiographic). The findings are discussed in terms of an integrative approach to personality.
  92. ncbi Basic oral health goals for Spain 2015/2020
    Manuel Bravo
    University of Granada, Spain
    Int Dent J 59:78-82; quiz 62. 2009
    To define the basic oral health goals for Spain 2015 (children)/2020 (adults).
  93. ncbi 'Obsessed with goals': functions and mechanisms of teleological interpretation of actions in humans
    Gergely Csibra
    School of Psychology, Birkbeck, University of London, Malet Street, London WC1E 7HX, United Kingdom
    Acta Psychol (Amst) 124:60-78. 2007
    ....
  94. ncbi The structure of goal contents across 15 cultures
    Frederick M E Grouzet
    School of Psychology, University of Ottawa, Ottawa, ON, Canada
    J Pers Soc Psychol 89:800-16. 2005
    ..Results suggested that the 11 types of goals the authors assessed were consistently organized in a circumplex fashion across the 15 cultures...
  95. ncbi Feature binding and episodic retrieval in blindness for congruent stimuli: evidence from analyses of sequential congruency
    Chris Oriet
    Department of Psychology, University of Regina, 3737 Wascana Parkway, Regina, Saskatchewan, S4S 0A2, Canada
    Psychol Res 71:30-41. 2007
    ..Implications for action planning and feature binding are discussed...
  96. doi Millennium development goals and the water target: details, definitions and debate
    Osman A Dar
    Imperial College Healthcare NHS Trust, London, UK
    Trop Med Int Health 16:540-4. 2011
    ..drinking water leave out some important elements that should be taken into account when determining whether the goals have been met...
  97. doi Choosing goals, not rules: deciding among rule-based action plans
    Christian Klaes
    Bernstein Center for Computational Neuroscience, Gottingen, Germany
    Neuron 70:536-48. 2011
    ..Movement goals must then be inferred from the sensory cue based on rules...
  98. ncbi What you want (and do not want) affects what you see (and do not see): avoidance social goals and social events
    Amy Strachman
    Psychology Department, University of California Los Angeles, Los Angeles, CA 90095, USA
    Pers Soc Psychol Bull 32:1446-58. 2006
    Two studies examined the influence of approach and avoidance social goals on memory for and evaluation of ambiguous social information...
  99. doi Goal attainment scaling (GAS) in rehabilitation: a practical guide
    Lynne Turner-Stokes
    Kings College London, School of Medicine, Regional Rehabilitation Unit, Northwick Park Hospital, Harrow, UK
    Clin Rehabil 23:362-70. 2009
    Goal attainment scaling is a mathematical technique for quantifying the achievement (or otherwise) of goals set, and it can be used in rehabilitation...
  100. pmc When do patients and their physicians agree on diabetes treatment goals and strategies, and what difference does it make?
    Michele Heisler
    Veterans Affairs Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI 48113 0170, USA
    J Gen Intern Med 18:893-902. 2003
    ..contributes to improved patient self-care by promoting greater agreement on patient-specific treatment goals and strategies...
  101. pmc Goal setting in diabetes self-management: taking the baby steps to success
    Darren A DeWalt
    Division of General Internal Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Patient Educ Couns 77:218-23. 2009
    To evaluate the usefulness of a diabetes self-management guide and a brief counseling intervention in helping patients set and achieve their behavioral goals.

Research Grants72

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  2. Discovery metabolite profiling of the prolyl peptidases
    Alan Saghatelian; Fiscal Year: 2009
    ..Furthermore, the application of DMP to peptidases will demonstrate the generality of this approach for the future characterization of medically relevant enzymes and signaling pathways. ..
  3. Personalized Clinical Diagnostics and Beyond: Integrated Ring Resonator Arrays
    Ryan Bailey; Fiscal Year: 2009
    ..This technology promises to broadly impact the landscape of the biomedical sciences, both meeting the clinical diagnostic challenges of today and pioneering the paradigm-shifting discoveries of tomorrow. ..
  4. Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex
    Derek Toomre; Fiscal Year: 2009
    ..Their advances will directly benefits goals of the DP2 and the new electronics and software's performance will be benchmarked and iteratively improved...
  5. NIH Director's Pioneer Award
    ERICH JARVIS; Fiscal Year: 2009
    ..Repairing the pathway in vocal learners, when damaged, would have profound impact for correcting neurological disorders of speech. ..
  6. Prevention of Complications in Thalassemia
    Elliott P Vichinsky; Fiscal Year: 2011
    ..Our future goals include expanded screening for cardiac iron deposition using newly available MRI technology and pulmonary ..
  7. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2012
    ..S. House of Representatives and U.S. Senate, ICCVAM and NICEATM prepared a five-year plan to describe goals and objectives for the years 2008 through 2012...
  8. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2011
    ..S. House of Representatives and U.S. Senate, ICCVAM and NICEATM prepared a five-year plan to describe goals and objectives for the years 2008 through 2012...
  9. National Network of Libraries of Medicine (NN/LM) Region 2
    Javier Crespo; Fiscal Year: 2010
    ..S. Virgin Islands. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  10. National Network of Libraries of Medicine (NN/LM) Region 2
    DENNIS PATTRATH; Fiscal Year: 2010
    ..S. Virgin Islands. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  11. National Network of Libraries of Medicine - Region 2
    JM J TOOEY; Fiscal Year: 2013
    ..S. Virgin Islands. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  12. National Network of Libraries of Medicine - Region 2
    JM J TOOEY; Fiscal Year: 2012
    ..S. Virgin Islands. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  13. National Network of Libraries of Medicine - Region 2
    JM J TOOEY; Fiscal Year: 2011
    ..S. Virgin Islands. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  14. National Network of Libraries of Medicine (NN/LM) Region 3
    Ruth Holst; Fiscal Year: 2010
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  15. Vaccine Development for Falciparum Malaria in Pregnant Women and Their Offspring
    Ian C Michelow; Fiscal Year: 2013
    ..He plans to accomplish his goals by acquiring critical new skills in the following three key areas: 1) vaccine immunology, 2) advanced molecular ..
  16. National Network of Libraries of Medicine (NN/LM) Region 3
    Ruth Holst; Fiscal Year: 2009
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  17. The Primate Corpus Luteum: Functional Regression and Cardiovascular Impacts
    Randy L Bogan; Fiscal Year: 2012
    ..Formal classes and training objectives are laid out to meet the aforementioned immediate goals. The research plan will address the novel hypothesis that cholesterol uptake and efflux activities, regulated by ..
  18. National Network of Libraries of Medicine - Region 3
    Ruth Holst; Fiscal Year: 2013
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  19. National Network of Libraries of Medicine - Region 3
    Ruth Holst; Fiscal Year: 2011
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  20. National Network of Libraries of Medicine - Region 3
    Ruth Holst; Fiscal Year: 2012
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  21. Role of NGF in inflammatory and proliferative cascades of psoriatic disease
    Siba P Raychaudhuri; Fiscal Year: 2012
    ..To determine these goals we are studying blood, joint fluid and joint tissues from patients with psoriatic arthritis and other forms of ..
  22. National Network of Libraries of Medicine (NN/LM) region 4
    Claire Hamasu; Fiscal Year: 2010
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  23. Ligand Directed Transdermal siRNA Delivery to Improve Wound Healing
    David M Evans; Fiscal Year: 2012
    ..Consequently, the primary goals in the treatment of wounds are rapid wound closure with minimal appearance of scarring...
  24. National Network of Libraries of Medicine (NN/LM) region 4
    Claire Hamasu; Fiscal Year: 2009
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  25. Tyrosine Availability Influences Mesocortico-Limbic Catecholamines
    GEORGE EUGENE JASKIW; Fiscal Year: 2012
    ..If recovery and reintegration into the community are goals, then currently available medications are highly unsatisfactory...
  26. Principles of Therapy in Cerebellar Disease: Explorations in Ion Channel Mutants
    JOHN SAMUEL STAHL; Fiscal Year: 2013
    ..The specific goals of the application include: 1)To determine whether one of the eye movement abnormalities of mice with cerebellar ..
  27. National Network of Libraries of Medicine (NN/LM) Region 5
    MICHELLE MALIZIA; Fiscal Year: 2010
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  28. National Network of Libraries of Medicine (NN/LM) Region 5
    MICHELLE MALIZIA; Fiscal Year: 2009
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  29. National Network of Libraries of Medicine (NN/LM) Region 6
    CATHY BURROUGHS; Fiscal Year: 2009
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  30. National Network of Libraries of Medicine (NN/LM) Region 7
    TAMARA COMBS; Fiscal Year: 2010
    ..S. Territories in the Pacific Basin. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  31. The influence of air pollution mixtures on biomarkers of airway oxidative stress
    Roby Greenwald; Fiscal Year: 2013
    The immediate career goals of the candidate, Dr. Roby Greenwald, are to examine the respiratory response to inhaled oxidants, specifically, the influence of air pollution mixtures on markers of airway inflammation and oxidative stress...
  32. Development of VN/14-1 and Related Analogs for Breast Cancer Therapy
    VINCENT COLLINS OFUKA NJAR; Fiscal Year: 2013
    ..34 and 1.41 hr, in mouse and rat, respectively. Therefore, in this application, one of our goals is to design and synthesize new analogs with improved in vivo stability and with anti-breast cancer activities as ..
  33. Sphingolipid Metabolism in Drosophila Development
    Julie D Saba; Fiscal Year: 2013
    ..Our long-term goals are to exploit Drosophila to elucidate the role of sphingolipids in biology, membrane function, and tissue ..
  34. Polycyclic aromatic hydrocarbons and birth outcomes in Mexico City
    MARIE SYLVIA O'NEILL; Fiscal Year: 2013
    ..Reducing infant mortality is one of the Millennium Development Goals, so the public health importance of understanding and minimizing environmental contributors to poor birth outcomes ..
  35. National Network of Libraries of Medicine - Region 4
    HAMASU CLAIRE; Fiscal Year: 2012
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  36. National Network of Libraries of Medicine - Region 4
    HAMASU CLAIRE; Fiscal Year: 2013
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  37. National Network of Libraries of Medicine - Region 8
    Javier Crespo; Fiscal Year: 2012
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  38. National Network of Libraries of Medicine - Region 8
    Javier Crespo; Fiscal Year: 2013
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  39. Metabolic Engineering of Bacteria for Cancer Immunotherapy by Gamma Delta T Cells
    Craig T Morita; Fiscal Year: 2013
    ..To accomplish our goals, we will: (1) metabolically engineer vaccine bacteria to overproduce HMBPP, (2) test engineered bacteria in vitro ..
  40. Behavioral Activation Therapy for Rural Veterans with Diabetes and Depression
    Aanand Dinkar Naik; Fiscal Year: 2013
    ..theory-based process for conducting the sessions with the aim of creating patient-centered and articulated goals and behavioral action plans...
  41. National Network of Libraries of Medicine - Region 8
    Javier Crespo; Fiscal Year: 2011
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  42. National Network of Libraries of Medicine - Region 4
    HAMASU CLAIRE; Fiscal Year: 2011
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  43. The Habenulo-Interpeduncular Pathway and Nicotine
    Christie D Fowler; Fiscal Year: 2013
    ..The immediate goals of this proposal are twofold: (1) to further define the mechanisms of the habenulo-interpeduncular pathway and its ..
  44. DNA Damage and Response in the Bladder Microenvironment.
    Bradley P Dixon; Fiscal Year: 2013
    ..The Candidate's immediate goals are to investigate these biological processes in a bladder microenvironment through both in vitro and in vivo ..
  45. National Network of Libraries of Medicine (NN/LM) Region 1
    Colleen Cuddy; Fiscal Year: 2010
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  46. Effect of PPARy Ligands on Alcohol-Induced Alveolar Macrophage Oxidative Stress
    Samantha M Yeligar; Fiscal Year: 2013
    ..The likelihood that she will achieve these goals is supported by planned mentorship from well-established investigators, the abundant scientific opportunities ..
  47. National Network of Libraries of Medicine - Region 6
    CATHY BURROUGHS; Fiscal Year: 2013
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  48. National Network of Libraries of Medicine - Region 6
    CATHY BURROUGHS; Fiscal Year: 2012
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  49. National Network of Libraries of Medicine - Region 5
    MICHELLE MALIZIA; Fiscal Year: 2013
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  50. National Network of Libraries of Medicine - Region 5
    MICHELLE MALIZIA; Fiscal Year: 2012
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  51. National Network of Libraries of Medicine - Region 5
    MICHELLE MALIZIA; Fiscal Year: 2011
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  52. National Network of Libraries of Medicine - Region 6
    CATHY BURROUGHS; Fiscal Year: 2011
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  53. Genetic and physiological causes of inherited Vascular and Metabolic Diseases
    Arya Mani; Fiscal Year: 2013
    ..The current study goals are investigating the effect of the mutation on metabolism of glucose and insulin secretion and function in ..
  54. National Network of Libraries of Medicine (NN/LM) Region 1
    KATE BURR OLIVER; Fiscal Year: 2009
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  55. Collagen X and heparan sulfate proteoglycan in the hematopoietic stem cell niche.
    ELIZABETH G SWEENEY; Fiscal Year: 2012
    ..an extension to the completed aims of a NRSA awarded to this investigator, and will provide data towards future goals of characterizing the extracellular matrix contribution to cytokine rich niches in development and disease...
  56. Skeletal Muscle. Ca Release Control Inside the Sarcoplasmic Reticulum.
    Eduardo Rios; Fiscal Year: 2013
    ..These goals are now feasible in living animals thanks to a DNA transfection method that works with every protein and can be ..
  57. Group A Streptococcus responses to oxidative stress
    Ioannis Gryllos; Fiscal Year: 2010
    ..The goals of this project are to characterize GAS adaptive responses coordinated by PerR under oxidative stress, and begin ..
  58. DNA methylation of extracellular superoxide dismutase in pulmonary hypertension
    EVA NOZIK GRAYCK; Fiscal Year: 2012
    ..The long term goals are to establish new pathways important in the regulation of this pivotal antioxidant enzyme in the vessel wall, ..
  59. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2009
    ..Prevention of eye injury is of great importance to human health. Two critically important goals are the replacement of the rabbit eye test with one or more alternative assay(s) that can provide equal or greater ..
  60. Role and Regulation of INrf2
    ANIL KUMAR JAISWAL; Fiscal Year: 2013
    ..The major goals of this proposal are to study role and regulation of INrf2. To this effect, we propose four specific aims...
  61. Molecular Markers for Progression of Pulmonary Fibrosis in Systemic Sclerosis
    Shervin Assassi; Fiscal Year: 2013
    ..Training Plan and Career Goals: The proposed four-year program provides intensive mentoring, didactic course work and independent scientific ..
  62. Pathobiology of Cystic Fibrosis-Related Diabetes in a Ferret Model
    Zoe Stewart; Fiscal Year: 2013
    ..To address the goals of Aim 1, we will use standard pancreatic endocrine functional tests to confirm that a subset of CF ferrets ..
  63. Mitochondrial dysfunction, oxidative stress, and surgical acute kidney injury
    FREDERIC TREMAINE BILLINGS; Fiscal Year: 2013
    ..His immediate career goals are to 1) Test the hypothesis that mitochondrial dysfunction contributes to oxidative and AKI following cardiac ..
  64. National Network of Libraries of Medicine - Region 7
    Julie Kwan; Fiscal Year: 2011
    ..S. Territories in the Pacific Basin. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  65. National Network of Libraries of Medicine - Region 7
    Julie Kwan; Fiscal Year: 2013
    ..S. Territories in the Pacific Basin. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  66. Androgen Modulation of Neurodegeneration in Dopamine Neurons
    Rebecca L Cunningham; Fiscal Year: 2010
    ..To be completed by applicant- follow PHS416-1 instructions) 20. GOALS FOR KIRSCHSTEIN-NRSA FELLOWSHIP TRAINING AND CAREER The training goals of this fellowship include learning ..
  67. National Network of Libraries of Medicine - Region 7
    Julie Kwan; Fiscal Year: 2012
    ..S. Territories in the Pacific Basin. The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  68. National Network of Libraries of Medicine - Region 1
    BARBARA EPSTEIN; Fiscal Year: 2012
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  69. National Network of Libraries of Medicine - Region 1
    BARBARA EPSTEIN; Fiscal Year: 2011
    ..The NN/LM goals are: to develop collaborations among network members and other organizations to improve access to and sharing of ..
  70. Transforming PCI Informed Consent into an Evidence-based Decision-making Tool
    John A Spertus; Fiscal Year: 2010
    ..e. those at the highest risk for bleeding) Finally, we will integrate all of these goals by formally assessing the cost-effectiveness of PCI after introducing PRISM into practice...
  71. STRUCTURE-BASED TUBERCULOSIS DRUG DESIGN TARGETED AT ACYL-COA CARBOXYLASE
    Shiou Chuan Tsai; Fiscal Year: 2010
    ..relevance to the mission of the agency). Describe concisely the research design and methods for achieving these goals. Describe the rationale and techniques you will use to pursue these goals...
  72. AGE, SENSATION AND FALLS--BIOMECHANICS AND PREVENTION
    Ge Wu; Fiscal Year: 1999
    The primary goals of this proposal are to study the biomechanics of posture at the level of single body segments in relation to age and peripheral sensory deficits in the visual and somatosensory systems that the aging process; also to ..