Genomes and Genes
Summary: The withholding of food in a structured experimental situation.
Publications254 found, 100 shown here
- The comparative physiology of food deprivation: from feast to famineTobias Wang
Department of Zoophysiology, Aarhus University, 8000 Aarhus C, Denmark
Annu Rev Physiol 68:223-51. 2006The ability of animals to survive food deprivation is clearly of considerable survival value. Unsurprisingly, therefore, all animals exhibit adaptive biochemical and physiological responses to the lack of food...
- Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleusF Damiola
, Sciences II, , CH-1211 Geneva, Switzerland
Genes Dev 14:2950-61. 2000..Food-induced phase resetting proceeds faster in liver than in kidney, heart, or pancreas, but after 1 wk of daytime feeding, the phases of circadian gene expression are similar in all examined peripheral tissues...
- Lifespan extension in Caenorhabditis elegans by complete removal of foodTammi L Kaeberlein
Department of Microbiology, University of Washington, Seattle, WA, USA
Aging Cell 5:487-94. 2006..Removal of bacterial food also increases lifespan when initiated in postreproductive adults, suggesting that dietary restriction started during middle age can result in a substantial longevity benefit that is independent of reproduction...
- Effects of short-term food deprivation on interoceptive awareness, feelings and autonomic cardiac activityBeate M Herbert
Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tuebingen, Eberhard Karls University Tuebingen, Germany
Biol Psychol 89:71-9. 2012..study investigated changes of interoceptive awareness and cardiac autonomic activity induced by short-term food deprivation and its relationship to hunger and affective experience...
- The relative-reinforcing value of food under differing levels of food deprivation and restrictionHollie A Raynor
State University of New York, University at Buffalo, Buffalo, NY 14214 3000, USA
Appetite 40:15-24. 2003b>Food deprivation and restriction both increase food consumption...
- Role and regulation of starvation-induced autophagy in the Drosophila fat bodyRyan C Scott
Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis 55455 USA
Dev Cell 7:167-78. 2004..Thus, in cells lacking TOR, autophagy plays a protective role that is dominant over its potential role as a growth suppressor...
- Fuel, fasting, fear: routine metabolic rate and food deprivation exert synergistic effects on risk-taking in individual juvenile European sea bassShaun S Killen
Institut des Sciences de l Evolution de Montpellier, UMR 5554 CNRS Université de Montpellier 2, Station Mediterraneenne de l Environnement Littoral, 1 Quai de la Daurade, F 34200 Sète, France
J Anim Ecol 80:1024-33. 2011..Such a relationship could be exacerbated by food deprivation if a higher metabolic demand also causes greater mass loss and hunger. 2...
- Food deprivation and emotional reactions to food cues: implications for eating disordersD J Drobes
NIMH Center for the Study of Emotion and Attention, University of Florida, Box 100165 HSC, Gainsville, FL 32610, USA
Biol Psychol 57:153-77. 2001..In experiment 1, normal college students were assigned to 0-, 6- or 24-h of food deprivation prior to presentations of standard emotional and food-related pictures...
- Rapid development of fasting-induced hepatic lipidosis in the American mink (Neovison vison): effects of food deprivation and re-alimentation on body fat depots, tissue fatty acid profiles, hematology and endocrinologyKirsti Rouvinen-Watt
Department of Plant and Animal Sciences, Nova Scotia Agricultural College, Truro, NS, Canada
Lipids 45:111-28. 2010..the timeline and characterize the development of hepatic lipidosis in mink in response to 0-7 days of food deprivation and liver recovery after 28 days of re-feeding...
- Discrimination of circadian phase in intact and suprachiasmatic nuclei-ablated ratsR E Mistlberger
Department of Psychology, Simon Fraser University, Burnaby, B C, Canada
Brain Res 739:12-8. 1996..The results provide the first clear evidence that the circadian system in a mammal can function as a consulted clock that provides discriminative time cues for cognitive processes subserving behavioral plasticity...
- Effects of deprivation on hedonics and reinforcing value of foodLeonard H Epstein
Department of Pediatrics, School of Medicine and Biomedical Sciences, University at Buffalo, G56 Farber Hall, 3435 Main Street, Buffalo, NY 14214 3000, USA
Physiol Behav 78:221-7. 2003..These results suggest that hedonics and the reinforcing value of food are separate processes in humans, and they may independently influence eating behavior...
- Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C. elegansKien Thiam Tan
Laboratory of Molecular Pathology, Institute of Molecular Biology, Academia Sinica, Taipei 115, Taiwan
Cell Metab 14:390-402. 2011..Upon depletion of the intestinal lipids, further food deprivation results in a significant reduction in metabolic activity in the starved male worms...
- The regulation of feeding and metabolism in response to food deprivation in Caenorhabditis elegansSarah Luedtke
School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK
Invert Neurosci 10:63-76. 2010This review considers the factors involved in the regulation of feeding and metabolism in response to food deprivation using Caenorhabditis elegans as a model organism...
- Hypothalamic orexin neurons regulate arousal according to energy balance in miceAkihiro Yamanaka
Institute of Basic Medical Science, University of Tsukuba, 305 8575, Ibaraki, Japan
Neuron 38:701-13. 2003..Transgenic mice, in which orexin neurons are ablated, fail to respond to fasting with increased wakefulness and activity. These findings indicate that orexin neurons provide a crucial link between energy balance and arousal...
- A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feedingKeiko Hirota
Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki 305 8577, Japan
J Biol Chem 283:32432-41. 2008....
- The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brainRobert Fredriksson
Department of Neuroscience, Functional Pharmacology, Uppsala University, Biomedical Center, Uppsala, Sweden
Endocrinology 149:2062-71. 2008..The FTO was significantly up-regulated (41%) in the hypothalamus of rats after 48-h food deprivation. We also found a strong negative correlation of the FTO expression level with the expression of orexigenic ..
- Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo techniqueCraig A Goodman
Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
FASEB J 25:1028-39. 2011..In addition, IV-SUnSET detected food deprivation-induced decreases in PS in the heart, kidney, and skeletal muscles, with similar changes being visualized ..
- Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feedingAngelo A Izzo
Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
Br J Pharmacol 158:451-61. 2009..Here we evaluate endocannabinoid dysregulation in the small intestine of mice with diet-induced obesity (DIO) and in peripheral tissues of Zucker and lean rats following food deprivation and re-feeding.
- Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated miceMasashi Akiyama
Department of Pharmacology, School of Science and Engineering, Waseda University, 2 7 5 Higashifushimi, Nishitokyo, 202 0021, Japan
Eur J Neurosci 20:3054-62. 2004..Based on these results, we suggest that activity of the orexin neuron in the LHA contributes to the promotion and maintenance of FAA...
- Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegansErica D Smith
Department of Pathology, University of Washington, Seattle, WA 98195, USA
BMC Dev Biol 8:49. 2008..Dietary restriction (DR) increases life span and delays age-associated disease in many organisms. The mechanism by which DR enhances longevity is not well understood...
- The functional costs and benefits of dietary restriction in DrosophilaJoep M S Burger
Department of Genetics, University of Georgia, Life Sciences Building, Athens, GA 30602 7223, USA
Aging Cell 6:63-71. 2007..Given the age-specific effects of DR on functional state, imposing DR late in life might not provide the same functional benefits as when applied at early ages...
- Effects of mild food deprivation on the estrous cycle of ratsJ Tropp
Behavioral Neuroscience Division, Department of Psychology, University of Connecticut, Box U-20, 406 Babbidge Road, 06269, Storrs, CT, USA
Physiol Behav 73:553-9. 2001It has long been known that severe food deprivation disrupts the estrous cycle. One of the main problems with behavioral tasks that use food for reinforcement is the requirement that the animal be food deprived...
- Analytical issues in the evaluation of food deprivation and sucrose concentration effects on the microstructure of licking behavior in the ratA C Spector
Department of Psychology, University of Florida, Gainesville 32611 2250, USA
Behav Neurosci 112:678-94. 1998..03-1.0 M) in daily single-bottle, 1-hr sessions was conducted. Food deprivation and concentration interacted to increase total licks...
- Evidence of increased dopamine receptor signaling in food-restricted ratsK D Carr
Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Neuroscience 119:1157-67. 2003..The signaling pathways mediating these augmented responses remain to be fully elucidated...
- Food deprivation alters osmoregulatory and metabolic responses to salinity acclimation in gilthead sea bream Sparus auratusSergio Polakof
Laboratorio de Fisioloxia Animal, Facultade de Ciencias do Mar, Edificio de Ciencias Experimentais, Universidade de Vigo, 36310, Vigo, Spain
J Comp Physiol B 176:441-52. 2006..b>Food deprivation abolished or attenuated the increase in gill Na+,K+-ATPase activity observed in LSW- and HSW-acclimated fish, ..
- Different colors reveal different information: how nutritional stress affects the expression of melanin- and structurally based ornamental plumageKevin J McGraw
Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 205:3747-55. 2002....
- Transcriptional feedback control of insulin receptor by dFOXO/FOXO1Oscar Puig
Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
Genes Dev 19:2435-46. 2005..Our results reveal a key feedback control mechanism for dFOXO/FOXO1 in regulating metabolism and insulin signaling...
- Nutrient-sensitive mitochondrial NAD+ levels dictate cell survivalHongying Yang
Department of Pathology, Paul F Glenn Laboratories, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Cell 130:1095-107. 2007..We discuss the relevance of these findings to understanding how nutrition modulates physiology and to the evolution of apoptosis...
- Direct and trans-generational responses to food deprivation during development in the Glanville fritillary butterflyM Saastamoinen
Department of Biosciences, University of Helsinki, Helsinki, Finland
Oecologia 171:93-104. 2013..We conducted a set of experiments to assess the direct and trans-generational effects of food deprivation in the Glanville fritillary butterfly Melitaea cinxia...
- Effects of food deprivation on goal-directed behavior, spontaneous locomotion, and c-Fos immunoreactivity in the amygdalaJ M Moscarello
Behavioral Pharmacology Laboratory, Department of Psychology, University of California, Santa Barbara, CA 93106 9660, USA
Behav Brain Res 197:9-15. 2009Previous work in our laboratory has shown that food deprivation and food presentation produce different patterns of neuronal activity (as measured by c-Fos immunoreactivity) in the medial prefrontal cortex and nucleus accumbens of rats...
- Dynamic interaction between medial prefrontal cortex and nucleus accumbens as a function of both motivational state and reinforcer magnitude: a c-Fos immunocytochemistry studyJustin M Moscarello
Behavioral Pharmacology Laboratory, Department of Psychology, University of California, Santa Barbara, CA 93106 9660, USA
Brain Res 1169:69-76. 2007This study examined the effects of simultaneous variations in motivational state (food deprivation) and reinforcer magnitude (food presentation) on c-Fos immunoreactivity in the pre- and infralimbic medial prefrontal cortex (mPFC), ..
- MTII attenuates ghrelin- and food deprivation-induced increases in food hoarding and food intakeErin Keen-Rhinehart
Department of Biology and Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA 30302 4010, USA
Horm Behav 52:612-20. 2007b>Food deprivation triggers a constellation of physiological and behavioral changes including increases in peripherally-produced ghrelin and centrally-produced agouti-related protein (AgRP)...
- Activation of the central nervous system in obese Zucker rats during food deprivationE Timofeeva
, , , Canada, G1K 7P4
J Comp Neurol 441:71-89. 2001..out to investigate the pattern of neuronal activations that occur in the obese fa/fa Zucker rat during food deprivation. The functional activation of neurons was estimated in lean and obese Zucker rats either fed ad libitum or ..
- Reintoxication: the release of fat-stored delta(9)-tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposureN Gunasekaran
School of Medical Science Pharmacology and Bosch Institute, The University of Sydney, Sydney, NSW, Australia
Br J Pharmacol 158:1330-7. 2009..Here we investigated whether conditions that promote lipolysis can liberate THC from adipocytes to yield increased blood levels of THC...
- Enhanced food anticipatory activity associated with enhanced activation of extrahypothalamic neural pathways in serotonin2C receptor null mutant miceJennifer L Hsu
Gladstone Institute of Neurological Disease, San Francisco, California, United States of America
PLoS ONE 5:e11802. 2010..in 5-HT2CR null mutant mice develops independent of external light cues and persists during two days of total food deprivation, indicating that food anticipatory activity in 5-HT2CR null mutant mice reflects the locomotor output of a ..
- The Drosophila foraging gene mediates adult plasticity and gene-environment interactions in behaviour, metabolites, and gene expression in response to food deprivationClement F Kent
Department of Biology, University of Toronto Mississauga, Ontario, Canada
PLoS Genet 5:e1000609. 2009..Here we show that variants of the foraging (for) gene in Drosophila melanogaster affect the response to food deprivation in a large suite of adult phenotypes by measuring gene by environment interactions (GEI) in a suite of food-..
- A daily palatable meal without food deprivation entrains the suprachiasmatic nucleus of ratsJorge Mendoza
Departamento de Anatomia, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, Mexico DF, 04510, Mexico
Eur J Neurosci 22:2855-62. 2005..Here we evaluated the entrainment influence of a daily palatable meal, without regular food deprivation, on the circadian rhythm of locomotor activity and the c-Fos and PER-1 protein expression in the SCN...
- Enhanced food-anticipatory circadian rhythms in the genetically obese Zucker ratR E Mistlberger
Department of Psychology, Simon Fraser University, Burnaby BC, Canada
Physiol Behav 66:329-35. 1999..Activity within this neuropeptide Y system is enhanced by food deprivation and attenuated by overfeeding and diet-induced obesity...
- Feeding cues alter clock gene oscillations and photic responses in the suprachiasmatic nuclei of mice exposed to a light/dark cycleJorge Mendoza
Laboratory of Neurobiology of Rhythms, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7518, Department of Neuroscience, Institut Fédératif de Recherche 37, University Louis Pasteur, F 67084 Strasbourg, France
J Neurosci 25:1514-22. 2005....
- After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalanceNicole M Avena
Department of Psychology, Princeton University, Princeton, NJ 08540, USA
Physiol Behav 94:309-15. 2008..This is similar to the effects of naloxone, suggesting opiate-like withdrawal. This may be a factor in some eating disorders...
- Molecular physiology of the neural circuit for calcineurin-dependent associative learning in Caenorhabditis elegansAtsushi Kuhara
Division of Biological Science, Graduate School of Science and Institute for Advanced Research, Nagoya University, Nagoya 464 8602, Japan
J Neurosci 26:9355-64. 2006..Our results demonstrate the molecular and physiological mechanisms of a simple neural circuit for calcineurin-mediated associative learning behavior...
- Unpredictable feeding schedules unmask a system for daily resetting of behavioural and metabolic food entrainmentCarolina Escobar
Departamento de Anatomia, Edificio B 4 Piso, Facultad de Medicina, Circuito Escolar s n, Universidad Nacional Autonoma de Mexico, Mexico DF 04510, Mexico
Eur J Neurosci 26:2804-14. 2007..The variable feeding strategy uncovered a rapid (24-h basis) resetting mechanism for metabolism and general behaviour...
- Food deprivation differentially modulates orexin receptor expression and signaling in rat hypothalamus and adrenal cortexEmmanouil Karteris
Biomedical Research Institute, Univ of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Am J Physiol Endocrinol Metab 288:E1089-100. 2005..Given that orexins are involved in regulating food intake and activating the HPA axis, we hypothesized that food deprivation, an acute challenge to the systems that regulate energy balance, should elicit changes in orexin receptor ..
- Diet and agingMatthew D W Piper
UCL Institute of Healthy Ageing, University College London, London, WC1E 6BT, UK
Cell Metab 8:99-104. 2008..Here we discuss examples of diet/genotype interactions that show a more complex mechanistic view is required and that mild dietary modifications can dramatically change the interpretation of model organism aging studies...
- Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathwayTor Erik Rusten
Department of Biochemistry, The Norwegian Radium Hospital, Montebello, N 0310 Oslo
Dev Cell 7:179-92. 2004..Hence, these studies link hormonal induction of autophagy to the regulatory function of the PI3K signaling pathway in vivo...
- Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide YJ C Erickson
Howard Hughes Institute, University of Washington, Seattle, USA
Nature 381:415-21. 1996..here that mice deficient for NPY have normal food intake and body weight, and become hyperphagic following food deprivation. Mutant mice decrease their food intake and lose weight, initially to a greater extent than controls, when ..
- Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogasterRichard Wong
Institute for Healthy Ageing, Darwin Building, University College London, Gower St, London, WC1E 6BT, UK
Nat Methods 5:214-5; author reply 215. 2008
- Elevated corticosterone associated with food deprivation upregulates expression in rat skeletal muscle of the mTORC1 repressor, REDD1Nora K McGhee
Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
J Nutr 139:828-34. 2009b>Food deprivation induces a repression of protein synthesis in skeletal muscle in part due to reduced signaling through the mammalian target of rapamycin complex 1 (mTORC1)...
- Differential effects of a restricted feeding schedule on clock-gene expression in the hypothalamus of the ratM C Minana-Solis
Departamento de Anatomia, Facultad de Medicina Universidad Nacional Autonoma de Mexico, Mexico, D F
Chronobiol Int 26:808-20. 2009..Present data highlight that metabolic or temporal cues elicited by feeding modify the temporal organization in the hypothalamus and are not exclusive for a food-entrained oscillator...
- Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylationDavid B Lombard
Howard Hughes Medical Institute, The Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
Mol Cell Biol 27:8807-14. 2007..Overall, our results extend the recent finding of lysine acetylation of mitochondrial proteins and demonstrate that SIRT3 has evolved to control reversible lysine acetylation in this organelle...
- The role of corticosterone in food deprivation-induced reinstatement of cocaine seeking in the ratUri Shalev
Behavioral Neuroscience Branch, IRP NIDA NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Psychopharmacology (Berl) 168:170-6. 2003Acute 1-day food deprivation stress reinstates heroin seeking in rats, but the generality of this effect to other drugs, and its underlying mechanisms, are largely unknown...
- Two strategies for coping with food shortage in desert golden spiny miceRoee Gutman
Department of Zoology, Tel Aviv University, Tel Aviv 69978, Israel
Physiol Behav 90:95-102. 2007..The use of two strategies to cope with food shortage as found in the golden spiny mice may be of evolutionary advantage, since it allows a more flexible reaction to food restriction at the population level...
- Immediate and delayed life history effects caused by food deprivation early in life in a short-lived lizardM Mugabo
Centre National de la Recherche Scientifique UMR 7625, Laboratoire Ecologie et Evolution, UPMC ENS Université Pierre et Marie Curie, 7 quai St Bernard, Paris, France
J Evol Biol 23:1886-98. 2010..Using the common lizard (Zootoca vivipara), we tested whether a food deprivation during the two-first months of life influence life history (growth, survival, reproduction) and performance ..
- Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein neuronsKanji A Takahashi
Vollum Institute and The Center for the Study of Weight Regulation and Associated Disorders, Oregon Health and Science University, Portland, Oregon 97239, USA
Endocrinology 146:1043-7. 2005..This is a remarkably straightforward example of a very robust in vitro electrophysiogical effect produced by a simple behavioral manipulation, food restriction...
- Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta have an attenuated response to cAMP and impaired carbohydrate metabolismC M Croniger
Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4935, USA
J Biol Chem 276:629-38. 2001..C/EBP beta influences the regulation of carbohydrate metabolism by altering the level of hepatic cAMP and the activity of protein kinase A...
- Long-term dietary restriction causes negative effects on cognitive functions in ratsShuichi Yanai
Department of Psychology, Doshisha University, Kyoto 602 8580, Japan
Neurobiol Aging 25:325-32. 2004....
- Overnight food deprivation markedly attenuates hindbrain noradrenergic, glucagon-like peptide-1, and hypothalamic neural responses to exogenous cholecystokinin in male ratsJames W Maniscalco
Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, United States
Physiol Behav 121:35-42. 2013..of A2, GLP-1, and mpPVN neurons would express cFos in rats after increasing doses of CCK, and that food deprivation would attenuate both hindbrain and hypothalamic neural activation...
- DAF-2 pathway mutations and food restriction in aging Caenorhabditis elegans differentially affect metabolismKoen Houthoofd
Department of Biology, Ghent University, K L Ledeganckstraat 35, B 9000 Ghent, Belgium
Neurobiol Aging 26:689-96. 2005..In addition, we provide evidence that DAF-2 signaling controls mitochondrial bioenergetics by adjusting the rate of ATP synthesis to the rate of ATP utilization and by regulating the heat-producing proton leak pathway...
- Effects of diabetes and food deprivation on shivering activity during progressive hypothermia in the ratR D Kilgour
Department of Exercise Science, Concordia University, Montreal, Quebec, Canada
Comp Biochem Physiol A Physiol 114:159-65. 1996Diabetes mellitus and food deprivation are two conditions known to significantly reduce the ability to generate body heat during periods of acute cold stress...
- Larval life history responses to food deprivation in three species of predatory lady beetles (Coleoptera: Coccinellidae)Mpho W Phoofolo
Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK 74078, USA
Environ Entomol 37:315-22. 2008..axyridis and then C. maculata. Percentage weight loss of larvae was affected by food deprivation period and coccinellid species. Both C. maculata and H. axyridis lost significantly more weight than H...
- Endocrine responses to short-term feed deprivation in weanling pigsB E Salfen
Animal Physiology Research Unit, ARS USDA, Columbia, Missouri, USA
J Endocrinol 178:541-51. 2003....
- Effects of food deprivation and refeeding on neuropeptide Y (NPY) mRNA levels in goldfishY K Narnaware
Department of Biological Sciences, University of Alberta, Alberta, T6G 2E9, Edmonton, Canada
Comp Biochem Physiol B Biochem Mol Biol 129:633-7. 2001..Taken together, these results further support that NPY is a physiological brain transducer involved in the regulation of daily appetite and feeding in goldfish...
- CCAAT/enhancer binding protein-delta expression is increased in fast skeletal muscle by food deprivation and regulates myostatin transcription in vitroDavid L Allen
Dept of Integrative Physiology, Univ of Colorado, Boulder, Campus Box 354, Boulder, CO 80309, USA
Am J Physiol Regul Integr Comp Physiol 299:R1592-601. 2010..C/EBP-δ mRNA and protein levels were significantly increased by 2 days of food deprivation in the tibialis anterior (TA) muscle, and expression of both myostatin and C/EBP-δ mRNA during food ..
- Influence of long-term food restriction on sleep pattern in male ratsTathiana A F Alvarenga
Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
Brain Res 1057:49-56. 2005..These results suggest that dietary restriction, regardless to the feeding schedule, caused increase in total sleep time, during the active period...
- Effects of post-ovulatory food deprivation on the hormonal profiles, activity of the oviduct and ova transport in sowsA M Mwanza
Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, Swedish University of Agricultural Sciences, Box 7039, SE 750 07, Uppsala, Sweden
Anim Reprod Sci 59:185-99. 2000The objective of the present study was to investigate the effect of post-ovulatory food deprivation on the hormonal profiles and consequently on the activity of the oviduct and ova transport in sows...
- Selective fatty acid mobilization in the American mink (Mustela vison) during food deprivationPetteri Nieminen
University of Joensuu, Department of Biology P O Box 111, FIN 80101, Joensuu, Finland
Comp Biochem Physiol B Biochem Mol Biol 145:81-93. 2006The mobilization of fatty acids (FAs) during food deprivation is a selective process in laboratory rodents and humans. The site-specific differences in adipose tissue functions - e.g...
- Plasma concentrations of leptin mirror changes in body weight but do not influence the pattern of the preovulatory luteinizing hormone surge in mink (Mustela vison)Anne Helene Tauson
Department of Animal Science and Animal Health, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
J Nutr 132:1790S-2S. 2002
- Effects of food deprivation on the development of Coleomegilla maculata (De Geer) (Coleoptera: Coccinellidae)T M Santos-Cividanes
Agência Paulista de Tecnologia dos Agronegócios, Ribeirao Preto, SP, Brasil
Neotrop Entomol 40:112-6. 2011..0% and 23.4% for larvae fed every two and three days, respectively. Coleomegilla maculata showed fecundity of 781.1 ± 149.02, 563.4 ± 80.81 and 109.0 ± 103.0 eggs when fed daily and at intervals of two and three days, respectively...
- Impact of postovulatory food deprivation on the ova transport, hormonal profiles and metabolic changes in sowsP Razdan
Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
Acta Vet Scand 42:45-55. 2001The effect of food deprivation on ova transport, hormonal profiles and metabolic changes was studied in 20 crossbred multiparous sows during their second oestrus after weaning...
- Food insecurity, food choices, and body mass index in adults: nutrition transition in Trinidad and TobagoMartin C Gulliford
Department of Public Health Sciences, King s College London, Nutrition and Metabolism Division, Ministry of Health, Laventille, Trinidad and Tobago
Int J Epidemiol 32:508-16. 2003..This study evaluated whether food insecurity and obesity were associated in a population sample in Trinidad...
- The arcuate NPY, POMC, and CART expressions responding to food deprivation are exaggerated in young female rats that experienced neonatal maternal separationS B Yoo
Department of Oral and Maxillofacial Surgery, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea
Neuropeptides 45:343-9. 2011..and cocaine-amphetamine regulated transcript (CART) were examined at two months of age with or without food deprivation. The basal arcuate expression levels of these peptides did not differ between NH and MS group...
- Feeding induced by food deprivation is differentially reduced by G-protein alpha-subunit antisense probes in ratsMaria M Hadjimarkou
Department of Psychology and Neuropsychology Doctoral Sub Program, Queens College, City University of New York, 65 30 Kissena Blvd, Flushing, NY 11367, USA
Brain Res 955:45-54. 2002..The present study examined whether food intake and weight changes elicited by 24 h of food deprivation were significantly altered by ventricular administration of antisense probes directed against either G(i)..
- The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemakerMichihiro Mieda
Laboratory of Molecular Neuroscience, School of Biomedical Science and Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113 8519, Japan
Proc Natl Acad Sci U S A 103:12150-5. 2006....
- Hungry for money: the desire for caloric resources increases the desire for financial resources and vice versaBarbara Briers
HEC School of Management, Paris, France
Psychol Sci 17:939-43. 2006..In Study 3, participants' desire for money affected the amount of M&M's they ate in a subsequent taste test, but only among participants who were not restricting their food intake in order to manage their weight...
- Correcting the short-term effect of food deprivation in a damselfly: mechanisms and costsMelina Campero
Laboratory of Aquatic Ecology, University of Leuven, Ch Deberiotstraat 32, B 3000 Leuven, Belgium
J Anim Ecol 77:66-73. 2008....
- Gastrin-releasing peptide messenger ribonucleic acid expression in the hypothalamic paraventricular nucleus is altered by melanocortin receptor stimulation and food deprivationEllen E Ladenheim
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Endocrinology 150:672-8. 2009..we investigated whether GRP mRNA expression in the PVN may be sensitive to challenges imposed by either 38 h food deprivation or stimulation of the melanocortin system by the melanocortin 3/4 receptor agonist, melanotan II (MTII)...
- A metabolomics approach to elucidate effects of food deprivation in juvenile rainbow trout (Oncorhynchus mykiss)Andreas Kullgren
Fish Endocrinology Laboratory, Dept of Zoology Zoophysiology, Univ of Gothenburg, Box 463, SE 405 30 Gothenburg, Sweden
Am J Physiol Regul Integr Comp Physiol 299:R1440-8. 2010..NMR-based metabolomics is a suitable method to generate an integrated view on metabolic processes during food deprivation in salmonid fish...
- Relationships of consumer characteristics and food deprivation to food purchasing behaviorD J Mela
Consumer Sciences Department, Institute of Food Research, Reading, UK
Physiol Behav 60:1331-5. 1996..behavior, and it is commonly believed that this may be significantly influenced by the shopper's state of food deprivation. In the present study, 198 subjects recruited just prior to shopping at a large supermarket completed ..
- Energy expenditure of rats subjected to long-term food restrictionF N Santos-Pinto
Disciplina de Fisiologia Renal e Termometabologia, Departamento de Fisiologia, , Rua Botucatu, 862, 5o andar, 04023-900 So Paulo, SP, Brazil
Int J Food Sci Nutr 52:193-200. 2001....
- Food deprivation increases post-heparin lipoprotein lipase activity in humansT Ruge
Department of Medical Biosciences, , , Sweden
Eur J Clin Invest 31:1040-7. 2001..CONCLUSIONS: In animal models such as rats and guinea pigs, post-heparin LPL activity decreases on fasting, presumably due to down-regulation of adipose tissue LPL. In humans, fasting caused increased post-heparin LPL activity...
- Darker eumelanic barn owls better withstand food depletion through resistance to food deprivation and lower appetiteAmelie Dreiss
Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland
Oecologia 164:65-71. 2010..Eumelanic coloration may therefore be associated with adaptations to environments where the risk of food depletion is high...
- Housing conditions influence the expression of food-anticipatory activity in miceMarleen H M de Groot
Department of Psychology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J1
Physiol Behav 83:447-57. 2004..g., those with different genotypes) should be interpreted cautiously, since at least one strain is strongly affected by a relatively minor procedural difference that was not anticipated to have a significant impact...
- Effects of acute food deprivation on eating behavior in eating disordersM M Hetherington
Department of Psychology, University of Dundee, Dundee, Scotland
Int J Eat Disord 28:272-83. 2000Effects of acute food deprivation on eating behavior in bulimic patients and controls were investigated. It was predicted that food deprivation would increase overall food intake and result in overeating in bulimics.
- A limited role for ghrelin in heroin self-administration and food deprivation-induced reinstatement of heroin seeking in ratsTia Maric
Department of Psychology, Center for Studies in Behavioral Neurobiology, Group de Recherche en neurobiologie comportementale, Concordia University, Montreal, QC, Canada
Addict Biol 17:613-22. 2012b>Food deprivation (FD) or restriction augments the locomotor activating and reinforcing effects of drugs of abuse...
- Circadian clocks for all meal-times: anticipation of 2 daily meals in ratsRalph E Mistlberger
Department of Psychology, Simon Fraser University, Burnaby, Canada
PLoS ONE 7:e31772. 2012..showed weak or no anticipation to one or both meals exhibited elevated activity at mealtime during 1 or 2 day food deprivation tests in DD, suggesting covert operation of circadian timing in the absence of anticipatory behavior...
- [Metabolic and endocrine effects of water and/or food deprivation in rats]Abir Grissa Kasdallah
Laboratoire de Physiologie Animale, Departement de Biologie, faculté des sciences de Tunis El Manar, Campus Universitaire, 1060 Tunis, Tunisie
C R Biol 328:463-70. 2005Metabolic and endocrine effects of water and/or food deprivation in rats...
- Placental protection of the fetal brain during short-term food deprivationKevin D Broad
Sub Department of Animal Behaviour, University of Cambridge, Cambridge CB23 8AA, United Kingdom
Proc Natl Acad Sci U S A 108:15237-41. 2011..We further show that challenging this genomic linkage of hypothalamus and placenta with 24-h food deprivation results in disruption to coexpressed genes, primarily by affecting placental gene expression...
- Modulation of methylphenidate effects on wheel running and acoustic startle by acute food deprivation in commercially and selectively bred ratsIan B McLaughlin
Department of Psychology, Occidental College, Los Angeles, CA 90041, USA
Pharmacol Biochem Behav 97:500-8. 2011..Modulation of the effects of methylphenidate (MPD) on wheel running and acoustic startle by food deprivation was examined in three experiments...
- Caloric restriction in primates and relevance to humansG S Roth
Laboratory of Neurosciences, Gerontology Research Center, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
Ann N Y Acad Sci 928:305-15. 2001....
- Food deprivation induces adipose plasminogen activator inhibitor-1 (PAI-1) expression without accumulation of plasma PAI-1 in genetically obese and diabetic db/db miceKatsutaka Oishi
Clock Cell Biology Research Group, National Institute of Advanced Industrial Science and Technology, Central 6, 1 1 1, Higashi, Tsukuba, Ibaraki 305 8566, Japan
Thromb Haemost 98:864-70. 2007Relationships between energy intake and fibrinolytic functions have been documented in detail. We evaluated food deprivation (FD) as a means of modulating fibrinolytic activity in genetically obese and diabetic db/db mice and in their ..
- AGS-3 alters Caenorhabditis elegans behavior after food deprivation via RIC-8 activation of the neural G protein G αoCatherine Hofler
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520 8024, USA
J Neurosci 31:11553-62. 2011..AGS-3 activates Gα(o) signaling in vivo to allow Caenorhabditis elegans to alter several behaviors after food deprivation, apparently so that the animals can more effectively seek food...
- Effect of food deprivation on the pulsatile LH release in the cycling and ovariectomized female ratF R Cagampang
Laboratory of Animal Reproduction, School of Agriculture, Nagoya University, Japan
Horm Metab Res 22:269-72. 1990The effect of food deprivation on the pulsatile release of LH was examined in the normal cycling and the ovariectomized (OVX) adult female rat...
- Effects of chronic food restriction and exercise training on the recovery of cardiac function following ischemiaT L Broderick
Department of Physiology, Midwestern University, Glendale, Arizona 85308, USA
J Gerontol A Biol Sci Med Sci 56:B33-7. 2001..Our results clearly indicate that the myocardium from the FR animal or the FR, exercise-trained rat is more resistant to ischemia...
- Prevention of adipose tissue depletion during food deprivation in angiotensin type 2 receptor-deficient miceLaurent Yvan-Charvet
Institut National de la Sante et de la Recherche Medicale, Unité 671, 15 rue de l Ecole de Medecine, 75270 Paris Cedex 06, France
Endocrinology 147:5078-86. 2006..These data reveal an important physiological role of AT2R in metabolic adaptations to fasting...
- Lateral hypothalamic signaling mechanisms underlying feeding stimulation: differential contributions of Src family tyrosine kinases to feeding triggered either by NMDA injection or by food deprivationArshad M Khan
Department of Cell Biology and Neuroscience, University of California, Riverside, California 92521, USA
J Neurosci 24:10603-15. 2004In rats, feeding can be triggered experimentally using many approaches. Included among these are (1) food deprivation and (2) acute microinjection of the neurotransmitter l-glutamate (Glu) or its receptor agonist NMDA into the lateral ..
- Interoceptive sensory signals produced by 24-hr food deprivation, pharmacological glucoprivation, and lipoprivationS C Benoit
Department of Psychological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
Behav Neurosci 110:168-80. 1996..The present research was designed to assess if they also give rise to interoceptive cues like 24-hr food deprivation. Rats were first trained to discriminate a mild shock based on interoceptive cues arising from 1- and 24-hr ..
- Perinatal food deprivation induces marked alterations of the hypothalamo-pituitary-adrenal axis in 8-month-old male rats both under basal conditions and after a dehydration periodNaima Sebaai
Laboratoire de Neuroendocrinologie du Developpement, UPRES EA 2701, Universite de Lille 1, Villeneuve d Ascq, France
Neuroendocrinology 79:163-73. 2004..We speculate that higher basal HPA activity and an inadequate HPA response after dehydration in mature animals may contribute to diseases such as hypertension, known to develop with aging in perinatally growth-restricted rats...
- Dietary restriction in two rotifer species: the effect of the length of food deprivation on life span and reproductionGuntram Weithoff
Institute for Biochemistry and Biology, University of Potsdam, Am Neuen Palais 10, 14469 Potsdam, Germany
Oecologia 153:303-8. 2007..These results suggest that in a temporally (or spatially) variable environment, some rotifer populations can persist even during long periods of severe food deprivation.
- Effects of food deprivation on host feeding and parasitism of whitefly parasitoidsLian Sheng Zang
Texas AgriLife Research, Weslaco, TX 78596, USA
Environ Entomol 39:912-8. 2010..The effects of food deprivation on host-feeding and parasitizing capacity of the whitefly parasitoids Eretmocerus melanoscutus and Encarsia ..
- Peptidomics of Cpe fat/fat mouse hypothalamus: effect of food deprivation and exercise on peptide levelsFa Yun Che
Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
J Biol Chem 280:4451-61. 2005..Twenty-eight peptides were increased >50% by food deprivation, and some of these were increased by 2- to 3-fold...
- Acute food deprivation and chronic food restriction differentially affect hypothalamic NPY mRNA expressionSheng Bi
Dept of Psychiatry and Behavioral Sciences, Johns Hopkins Univ School of Medicine, 720 Rutland Ave, Ross 618, Baltimore, MD 21205, USA
Am J Physiol Regul Integr Comp Physiol 285:R1030-6. 2003Although acute food deprivation and chronic food restriction both result in body weight loss, they produce different metabolic states...
- The gastric X/A-like (ghrelin) cell: A peripheral regulator of food intakeNILS WG LAMBRECHT; Fiscal Year: 2012..and nesfatin- 1/NUCB2 cellular expression, peptide modification and release into the circulation: a) 24 h food deprivation compared to ad libitum feeding and b) acute inflammation compared to healthy rats (peritoneal injection of ..
- Response to and signals of caloric restriction and intermittent feeding regimensMARC KOPEL HELLERSTEIN; Fiscal Year: 2010..First, a life-time of food deprivation and reduced body weight is not practical for most people;and, second, it has not been easy to identify the ..
- Ghrelin: Behavioral, Anatomical, and Physiological Components of ObesityBRETT JOHN WARREN TEUBNER; Fiscal Year: 2011..the physiological range, increases ingestive behaviors in Siberian hamsters to nearly identical levels as food deprivation [36-56 hrs (IACUC approved), as shorter ones do not impact these behaviors due to their ample lipid stores]...
- The Role of Leptin in the Maintenance of a Reduced Body WeightChristos S Mantzoros; Fiscal Year: 2012..Our group has shown that decreasing leptin levels mediate the neuroendocrine response to food deprivation in both animals and humans...
- Significance of Pituitary Leptin to GonadotropesGwen V Childs; Fiscal Year: 2010..There are parallel reductions in pituitary leptin and LH during food deprivation and a parallel recovery mediated by glucose...
- CHARACTERIZATION OF A NEW FAMILY OF PROTEIN KINASESKirill M Popov; Fiscal Year: 2012..PUBLIC HEALTH RELEVANCE: The long-term regulation of PDHK activity is central to adaptation to food deprivation, hypoxia, high-fat diet, etc...
- Central Regulation of Hepatic Energy StoresAllison W Xu; Fiscal Year: 2013..component of the overall adaptive regulation by leptin to ensure energy availability during long period of food deprivation. This mechanism may also operate in diet-induced obesity in that impairment of leptin signaling due to leptin ..
- Mechanisms of Oxidative Stress and Inflammation during Prolonged Fasting and SleeRudy M Ortiz; Fiscal Year: 2013..or alleviate the consequences of oxidative stress and inflammation commonly associated with protracted food deprivation and sleep apnea in humans in an effort to identify novel therapeutic targets...
- Effects of food deprivation on sexual behaviorMICHAEL FERKIN; Fiscal Year: 2009..The proposal is to use an animal model (the meadow vole) to examine the effects of food deprivation on three aspects of reproductive behavior (attractivity, proceptivity, and receptivity) as well as the ..
- REGULATION OF ION CHANNELS IN NERVE CELLSIRWIN LEVITAN; Fiscal Year: 2009..brain;and (4) mutant flies in which Slob expression is decreased exhibit locomotor rhythm defects and survive food deprivation much longer than their wild type counterparts...
- Neurocognitive Mechanisms of Decisions and Impulse Control in Nutrition BehaviorAntoine Bechara; Fiscal Year: 2013..We will also test the hypothesis that food deprivation induces an increased activation of the insular cortex with the consequence of exacerbating activity of the ..
- ENVIRONMENTAL AND PHARMACOLOGICAL CONTROL OF DRUG ABUSEMarilyn Carroll; Fiscal Year: 2000..Some groups of 5 rats will have behavioral interventions such as food satiation, food deprivation or access to an alternative reinforcer such as orally-delivered G+S or ethanol (8%)...
- Small RNAs: Regulation and Regulatory Activity in Body Weight ControlRoderick V Jensen; Fiscal Year: 2010..experiments will characterize a potentially new method for hypothalamic gene regulation during food intake, food deprivation or in obese individuals with high levels of circulating leptin...
- Promoter characterization of the CART geneMichael J Kuhar; Fiscal Year: 2010..it has been shown that CART levels do change quickly (in hours) in response to cocaine and amphetamine and food deprivation, for example...
- Characterization of Taste-independent Sugar Sensor in the BrainGreg S B Suh; Fiscal Year: 2013..still developed a preference for a sugar solution based on its nutritional value after prolonged periods of food deprivation. Specifically, these starved sugar-blind or taste-blind flies were able to distinguish nutritious D-glucose ..
- EMPHYSEMA--INFLUENCES ON DIAPHRAGM FATIGUE RESISTANCEMichael Lewis; Fiscal Year: 1992..Adult male Sprague Dawley rats will be studied. The induction of PCM will be achieved by prolonged food deprivation over 4 weeks. Emphysema will be induced by a single intratracheal installation of pancreatic porcine elastase...
- Developmental Control in C. elegansMin Han; Fiscal Year: 2013..approach will further be used to identify dynamic miRNA::target interactions during animals'responses to food deprivation, pathogen infection and other stresses...
- Hypothalamic Type 2 Deiodinase in Metabolism RegulationSabrina Diano; Fiscal Year: 2005..leptin and elevating corticosterone levels that disrupts normal thyroid feedback during short-term food deprivation. The following Specific Aims will test our hypotheses: Specific Aim 1...
- A Novel Cytoprotective Peptide for GI Epithelial CellFREDERICK TOBACK; Fiscal Year: 2005..intracecal Pseudomonas aeruginosa following the surgical stress of partial hepatectomy and post-operative food deprivation in a model GDS...
- Genes underlying food-related behaviors in Drosphila.MARLA SOKOLOWSKI; Fiscal Year: 2007..in the regulation of hunger and satiation: The normal behavioral response of a larva to an acute period of food deprivation is to increase its food intake and reduce its locomotor activity...
- NEUROPEPTIDE Y--EFFECTS ON ENERGY METABOLISMCharles Billington; Fiscal Year: 2001..activated by NPY in hypothalamic paraventricular nucleus, opioids in nucleus of the solitary tract, and by food deprivation through examining site specific expression of the immediate early gene, c-fos; (2) Verify the functional ..
- ENVIRONMENTAL CONTROL OF OVULATIONLAWRENCE MORIN; Fiscal Year: 1990Short photoperiod, prolonged cold exposure, lactation and food deprivation all produce anovulation in the female hamster...
- HINDBRAIN AND NEUROPEPTIDE Y--CONTROL OF FOOD INTAKEERIC CORP; Fiscal Year: 2002..the larger NPY neural circuitry, I propose additionally to investigate NPY gene expression in response to food deprivation in locus coeruleus and dorsal tegmental nuclei, two dorsal pontine loci with NPY efferent projections to ..
- Chronic stress intensifies incentive relativityMary Dallman; Fiscal Year: 2006..High B (and/or food deprivation) intensifies incentive relativity effects on a maze; and, 4...
- EFFECT OF DIETING ON ALCOHOL AND DRUG USE IN YOUNG WOMENDean Krahn; Fiscal Year: 1993..Animal studies have suggested that increased drug intake may be caused by food deprivation. Because the onset of clinically significant eating disorders usually antedates the onset of clinically ..
- Homeostatic Substrates of Incentive Re-ValuationNorman Pecoraro; Fiscal Year: 2004..Relativity effects will be exacerbated in a second set of animals by food deprivation. Radioimmunoassays and telemetry will determine whether 32% sucrose solutions entrain circadian feeding ..
- INCREASING THE REINFORCING EFFECTIVENESS OF ETHANOLHENRY MARCUCELLA; Fiscal Year: 1980..The concentration of ethanol and the subject state of food deprivation affect the amount of ethanol consumed, the duration of ethanol availability and non-availability periods ..
- The Effects of Sleep Deprivation on Cocaine Self-Administration and RelapseMatthew D Puhl; Fiscal Year: 2010..Similarly, CORT has been shown to play a permissive role in relapse induced by food deprivation. Therefore, the plasma CORT response to the acute IV administration of cocaine will also be assessed ..
- MORPHINE AND FEEDING BEHAVIOR: PATTERNS OF INTERACTIONROBIN KANAREK; Fiscal Year: 1980..effects of variables associated with food intake on narcotic administration, it has been recently shown that food deprivation leads to increased intakes of opioid solutions...
- Metabolic regulation of midbrain dopamine neuronsRobert MacKenzie; Fiscal Year: 2005..b>Food deprivation enhances feeding, drug self-administration, relapse to drug-taking and self-stimulation reward...
- EARLY HUSBANDRY INFLUENCES ON ADULT PHENOTYPEMICHAEL TORDOFF; Fiscal Year: 2009..g., food deprivation, water deprivation, temperature, motion)on adult phenotype...
- CRH Antagonists for Treatment of Drug AbuseJames Woods; Fiscal Year: 2005..v. administration of CRH, i.v. administration of the CRH R1 agonist EG12114, footshock, social defeat, and food deprivation. Initially, the effect of each stressor on ACTH and corticosterone levels will be determined...
- CHANGES IN BRAIN ASTROCYTES WITH AGINGDavid Morgan; Fiscal Year: 1991..of the increase in GFAP-RNA in these wasting mice will be sought by examining select aspects of the model; food deprivation, tumor transplantation, immune system reactivity and other conditions will be tested. Study IV: Intrinsic vs...
- Quantitative Peptidomics of Food DeprivationLloyd Fricker; Fiscal Year: 2005..of peptides in mouse hypothalamus, of which 20-30% are substantially up- or down-regulated by 2 days of food deprivation. In Aim 1, we will identify these peptides using tandem mass spectrometry...
- THE EFFECT OF FOOD DEPRIVATION ON CIGARETTE SMOKINGFrank Collins; Fiscal Year: 1991..Research in behavioral pharmacology has indicated that drug reinforced behaviors increase during food deprivation. Specifically, animals that have been trained to self-administer drugs will show increased rates in self ..
- EFFECT OF FOOD/TASTE PREFERENCES ON DRUG INTAKEDean Krahn; Fiscal Year: 1992..Previous studies, including our own preliminary investigations, have shown that: (1) food deprivation causes significant changes in the self-administration of a variety of drugs (as well as changes in fat and ..
- BEHAVIORAL/BIOLOGICAL DETERMINANTS OF ETHANOL PREFERENCEDzung Le; Fiscal Year: 1993..differences in ethanol preference, 2) an examination into how behavioral manipulations such as stress and food deprivation, which have been shown to enhance ethanol consumption, might affect these three factors, and 3) an ..
- OPIOID MECHANISMS THAT FACILITATE REWARDKENNETH CARR; Fiscal Year: 2006..abstract_text> ..
- CNS Mechanisms that Modulate RewardKENNETH CARR; Fiscal Year: 2008..The research proposed in this application is aimed at elucidating midbrain and striatal mechanisms involved in the increased behavioral responsiveness of FR rats to drugs of abuse. ..
- The Role of Melanocortin 4 Receptors in Energy BalanceJULI JONES; Fiscal Year: 2005....
- Matrix Metalloproteinases, Exercise, and Muscle DamageDavid Allen; Fiscal Year: 2008..Finally, subjects will be genotyped for known functional MMP promoter polymorphisms, which will be correlated with MMP levels and muscle damage and soreness following eccentric exercise. ..
- Dorsomedial Hypothalamic Pathways and Energy BalanceSheng Bi; Fiscal Year: 2005..Together, these neurochemical and functional demonstrations will provide a clear view of the role of the DMH in energy balance ..
- Dorsomedial Hypothalamic Signaling Pathways and Energy BalanceSheng Bi; Fiscal Year: 2010..Overall, the elucidation of the actions of these DMH peptide systems in feeding and body weight control would significantly advance our understanding of the role of this hypothalamic nucleus in maintaining energy homeostasis. ..
- Leptin and Neuroendocrine Gene Regulation in ObesityJudith Korner; Fiscal Year: 2005..Leibel and Dr. Wardlaw, are experienced in basic and clinical research. They are easily accessible, enthusiastic about my projects, and will facilitate my transition to status as an independent investigator. ..
- Leptin and Neuroendocrine Gene Regulation in ObesityJudith Korner; Fiscal Year: 2005..abstract_text> ..
- TRH in mediating the bradycardia of caloric restrictionSteven Swoap; Fiscal Year: 2005..Resting and intrinsic HRs will be measured before and during a caloric restriction period. ..
- Cocaine Self Administration and Relapse in Mice:Gene delLAWRENCE MIDDAUGH; Fiscal Year: 2003..These studies will significantly advance the use of the mouse species as a model for drug abuse and contribute toward establishing appropriate therapies for addiction. ..
- CONTROL OF ALCOHOL INTAKE BY BRAIN-GUT PEPTIDESNORCROSS GEARY; Fiscal Year: 2003..The work will be closely coordinated, and we expect this cooperative effort to be very productive. ..
- ONTOGENY OF METABOLIC CONTROLS OF INGESTIVE BEHAVIORSUSAN SWITHERS; Fiscal Year: 2002..e. food deprivation)...
- Physiology and genetics of food procurement in rodentsNeil Rowland; Fiscal Year: 2008..The proposed studies will be the first to address the issue of behavioral change induced by anorectics under such conditions of simulated economic costs. [unreadable] [unreadable] [unreadable]..
- Rapid Metabolic Control of the HPG SystemJILL SCHNEIDER; Fiscal Year: 2007..Comparisons of species from two different taxa will test the generality of the conclusions. ..
- OVARIAN HORMONAL CONTROL OF MEAL SIZENORCROSS GEARY; Fiscal Year: 2008..8) Determine the tonic and phasic effects of estradiol on glutamate synaptogenesis in the brainstem by using immunocytochemical detection of synaptic proteins. [unreadable] [unreadable]..
- Imprint Osmoregulation/Maternally-Dehydrated OffspringMina Desai; Fiscal Year: 2007..We will determine the molecular and cellular mechanism(s) and peripheral renal AVP receptor changes. Finally, we will delineate the critical period during which imprinting of the AVP/osmoregulatory pathway occurs. ..
- ANTIDEPRESSANT THERAPY AND HYPOGLYCEMIADianne Lattemann; Fiscal Year: 2006..non-diabetic rats. The results of these studies will provide new knowledge that ultimately may assist primary physicians in determining the most advantageous treatment for their diabetic patients with depression. ..
- HYPOTHALAMIC NEUROTRANSMITTER SYSTEMS & EATING BEHAVIORSarah F Leibowitz; Fiscal Year: 2010..In summary, this grant tests the novel hypothesis that a high-fat diet itself can promote overeating and ultimately dietary obesity through a positive feedback loop involving circulating lipids, hypothalamic peptides and accumbens DA. ..
- Gender-Specific Ontogenic Cocaine Effects: NeuroanatomyDiana Dow Edwards; Fiscal Year: 2006..Together these studies will examine the neuroanatomic basis for developmental cocaine's effects on function in males and females and determine the roles of gonadal steroids in producing these effects. ..
- Hindbrain integration of adiposity and satiety signalsDiana Williams; Fiscal Year: 2007..unreadable] [unreadable]..
- GLYCOSPHINGOLIPIDS IN MURINE NEURODEGENERATIVE DISEASESTHOMAS SEYFRIED; Fiscal Year: 2009..The proposed studies will provide essential information on combinatorial therapies for the ganglioside storage diseases and will have translational benefit to the clinic. ..
- GLYCOSPHINGOLIPIDS IN MURINE NEURODEGENERATIVE DISEASESTHOMAS SEYFRIED; Fiscal Year: 2004..Since there are no effective treatments for human ganglioside storages disease, the proposed research could offer a novel therapy for the early intervention of these neurodegenerative disorders. ..
- Nutritional Regulation of Fetal Liver DevelopmentPHILIP GRUPPUSO; Fiscal Year: 2008..Furthermore, we anticipate that our findings will relate to diverse areas of liver biology, including the hepatic response to liver injury, hepatic carcinogenesis, and liver stem cell biology. [unreadable] [unreadable]..