Summary: The observable response a person makes to any situation.

Top Publications

  1. ncbi The neural basis of economic decision-making in the Ultimatum Game
    Alan G Sanfey
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Science 300:1755-8. 2003
  2. ncbi Contributions of the amygdala to emotion processing: from animal models to human behavior
    Elizabeth A Phelps
    Department of Psychology, New York University, 4 6 Washington Place, New York, New York 10003, USA
    Neuron 48:175-87. 2005
  3. pmc Social contagion theory: examining dynamic social networks and human behavior
    Nicholas A Christakis
    Department of Medicine, Harvard Medical School, Boston, MA 02115, U S A
    Stat Med 32:556-77. 2013
  4. ncbi Changing human behavior to prevent disease: the importance of targeting automatic processes
    Theresa M Marteau
    Behaviour and Health Research Unit, Institute of Public Health, University of Cambridge, Cambridge CB2 0SR, UK
    Science 337:1492-5. 2012
  5. ncbi Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans
    Adam R Aron
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge CB2 2QQ, UK
    Nat Neurosci 6:115-6. 2003
  6. pdf Action and behavior: a free-energy formulation
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, UK
    Biol Cybern 102:227-60. 2010
  7. pmc Arc in synaptic plasticity: from gene to behavior
    Erica Korb
    Gladstone Institute of Neurological Disease, San Francisco, CA, USA
    Trends Neurosci 34:591-8. 2011
  8. ncbi Reinforcement learning signal predicts social conformity
    Vasily Klucharev
    Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, 6500 HB Nijmegen, The Netherlands
    Neuron 61:140-51. 2009
  9. ncbi Sedentary behavior, physical activity, and the metabolic syndrome among U.S. adults
    Earl S Ford
    Division of Adult and Community Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Obes Res 13:608-14. 2005
  10. pmc Neurogenesis, inflammation and behavior
    Rachel A Kohman
    Department of Psychology, Beckman Institute, 405 N Mathews Ave, Urbana, IL 61801, United States
    Brain Behav Immun 27:22-32. 2013

Detail Information

Publications321 found, 100 shown here

  1. ncbi The neural basis of economic decision-making in the Ultimatum Game
    Alan G Sanfey
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Science 300:1755-8. 2003
    ..Further, significantly heightened activity in anterior insula for rejected unfair offers suggests an important role for emotions in decision-making...
  2. ncbi Contributions of the amygdala to emotion processing: from animal models to human behavior
    Elizabeth A Phelps
    Department of Psychology, New York University, 4 6 Washington Place, New York, New York 10003, USA
    Neuron 48:175-87. 2005
    ..amygdala in humans and other animals, including implicit emotional learning and memory, emotional modulation of memory, emotional influences on attention and perception, emotion and social behavior, and emotion inhibition and regulation.
  3. pmc Social contagion theory: examining dynamic social networks and human behavior
    Nicholas A Christakis
    Department of Medicine, Harvard Medical School, Boston, MA 02115, U S A
    Stat Med 32:556-77. 2013
  4. ncbi Changing human behavior to prevent disease: the importance of targeting automatic processes
    Theresa M Marteau
    Behaviour and Health Research Unit, Institute of Public Health, University of Cambridge, Cambridge CB2 0SR, UK
    Science 337:1492-5. 2012
    ..These approaches are often ineffectual, which is in keeping with the observation that much human behavior is automatic, cued by environmental stimuli, resulting in actions that are largely unaccompanied by conscious ..
  5. ncbi Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans
    Adam R Aron
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge CB2 2QQ, UK
    Nat Neurosci 6:115-6. 2003
  6. pdf Action and behavior: a free-energy formulation
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, UK
    Biol Cybern 102:227-60. 2010
    ..Furthermore, it accounts for many aspects of motor behavior; from retinal stabilization to goal-seeking...
  7. pmc Arc in synaptic plasticity: from gene to behavior
    Erica Korb
    Gladstone Institute of Neurological Disease, San Francisco, CA, USA
    Trends Neurosci 34:591-8. 2011
    ..We will also attempt to clarify how its molecular functions correspond to its requirement in various forms of plasticity, discuss Arc's role in behavior and disease, and highlight critical unresolved questions.
  8. ncbi Reinforcement learning signal predicts social conformity
    Vasily Klucharev
    Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, 6500 HB Nijmegen, The Netherlands
    Neuron 61:140-51. 2009
    We often change our decisions and judgments to conform with normative group behavior. However, the neural mechanisms of social conformity remain unclear...
  9. ncbi Sedentary behavior, physical activity, and the metabolic syndrome among U.S. adults
    Earl S Ford
    Division of Adult and Community Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Obes Res 13:608-14. 2005
    We examined the associations among physical activity, sedentary behavior, and metabolic syndrome in a representative sample of U.S. adults.
  10. pmc Neurogenesis, inflammation and behavior
    Rachel A Kohman
    Department of Psychology, Beckman Institute, 405 N Mathews Ave, Urbana, IL 61801, United States
    Brain Behav Immun 27:22-32. 2013
    ..other immune-reactive cells in the brain can support or disrupt neural processes depending on the phenotype and behavior of the cells...
  11. pmc Synaptic AMPA receptor plasticity and behavior
    Helmut W Kessels
    Department of Neuroscience, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0634, USA
    Neuron 61:340-50. 2009
    The ability to change behavior likely depends on the selective strengthening and weakening of brain synapses...
  12. pmc Defecting or not defecting: how to "read" human behavior during cooperative games by EEG measurements
    Fabrizio de Vico Fallani
    NEILab, Scientific Institute for Research Hospitalization and Health Care IRCCS Fondazione Santa Lucia, Rome, Italy
    PLoS ONE 5:e14187. 2010
    ..e., the tendency to form two separate subgraphs--than couples playing cooperative or tit-for-tat strategies. The decision to defect can be "read" in advance by evaluating the changes of connectivity pattern in the hyper-brain network...
  13. pmc Student behavior during a school closure caused by pandemic influenza A/H1N1
    Joel C Miller
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 5:e10425. 2010
    ..The effectiveness of closing schools to reduce transmission depends largely on student/family behavior during the closure. We sought to improve our understanding of these behaviors.
  14. ncbi The revolution that wasn't: a new interpretation of the origin of modern human behavior
    S Mcbrearty
    Department of Anthropology, University of Connecticut, Storrs, Connecticut 06269, USA
    J Hum Evol 39:453-563. 2000
    ..sapiens. The appearance of Middle Stone Age technology and the first signs of modern behavior coincide with the appearance of fossils that have been attributed to H. helmei, suggesting the behavior of H...
  15. pmc Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans
    Mathias Pessiglione
    Wellcome Department of Imaging Neuroscience, 12 Queen Square, London WC1N 3BG, UK
    Nature 442:1042-5. 2006
    ..We conclude that dopamine-dependent modulation of striatal activity can account for how the human brain uses reward prediction errors to improve future decisions...
  16. pmc Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 years: a randomized, controlled trial (the DOLAB Study)
    Alexandra J Richardson
    Centre for Evidence Based Intervention, University of Oxford, Oxford, United Kingdom
    PLoS ONE 7:e43909. 2012
    ..Evidence from clinical trials indicates that dietary supplementation with long-chain omega-3 may improve child behavior and learning, although most previous trials have involved children with neurodevelopmental disorders such as ..
  17. pmc Experience sampling during fMRI reveals default network and executive system contributions to mind wandering
    Kalina Christoff
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada V6Z 2R8
    Proc Natl Acad Sci U S A 106:8719-24. 2009
    Although mind wandering occupies a large proportion of our waking life, its neural basis and relation to ongoing behavior remain controversial...
  18. pmc Priming intelligent behavior: an elusive phenomenon
    David R Shanks
    Division of Psychology and Language Sciences, University College London, London, United Kingdom
    PLoS ONE 8:e56515. 2013
    Can behavior be unconsciously primed via the activation of attitudes, stereotypes, or other concepts? A number of studies have suggested that such priming effects can occur, and a prominent illustration is the claim that individuals' ..
  19. ncbi The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking
    S Ikemoto
    Behavioral Neuroscience Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224, USA
    Brain Res Brain Res Rev 31:6-41. 1999
    ..motivated behaviors accumulate, it is necessary to accommodate such data for understanding the role of NAS DA in behavior. The aim of the present paper is to provide a unifying interpretation that can account for the functions of NAS ..
  20. pmc Optogenetic tools for analyzing the neural circuits of behavior
    Jacob G Bernstein
    MIT Media Lab and McGovern Institute, Departments of Brain and Cognitive Sciences, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Trends Cogn Sci 15:592-600. 2011
    ..We describe this optogenetic toolbox, how it can be used to analyze neural circuits in the brain and how optogenetics is impacting the study of cognition...
  21. ncbi Task set and prefrontal cortex
    Katsuyuki Sakai
    Department of Cognitive Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Annu Rev Neurosci 31:219-45. 2008
    ..The processes of representing, updating, and implementing task sets occur in parallel at multiple levels of brain organization. Neural accounts of task sets demonstrate that the brain determines our thoughts and behaviors...
  22. pmc Conscious and subliminal conflicts in normal subjects and patients with schizophrenia: the role of the anterior cingulate
    Stanislas Dehaene
    Institut National de la Santé et de la Recherche Médicale Commissariat à l Energie Atomique Unit 562 Cognitive Neuroimaging, Service Hospitalier Frederic Joliot, Orsay Cedex, France
    Proc Natl Acad Sci U S A 100:13722-7. 2003
    ..Those findings suggest that subliminal conflicts are resolved without ACC contribution and that the ACC participates in a distributed conscious control network that is altered in schizophrenia...
  23. ncbi The unconscious will: how the pursuit of goals operates outside of conscious awareness
    Ruud Custers
    Department of Psychology, Utrecht University, Heidelberglaan 1, 3584 CS Utrecht, Netherlands
    Science 329:47-50. 2010
    ..behavioral science recognizes that people can skillfully pursue goals without consciously attending to their behavior once these goals are set, conscious will is considered to be the starting point of goal pursuit...
  24. ncbi A cortical network sensitive to stimulus salience in a neutral behavioral context across multiple sensory modalities
    Jonathan Downar
    Institute of Medical Science, University of Toronto, Canada
    J Neurophysiol 87:615-20. 2002
    ..A frontal-parietal-cingulate network may serve to identify and evaluate salient sensory stimuli in general...
  25. ncbi Neural mechanisms of transient and sustained cognitive control during task switching
    Todd S Braver
    Department of Psychology, Washington University, St Louis, MO 63130, USA
    Neuron 39:713-26. 2003
  26. pmc Dorsal anterior cingulate cortex: a role in reward-based decision making
    George Bush
    Department of Psychiatry, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:523-8. 2002
    ..These findings should be of interest to those studying reward, cognition, emotion, motivation, and motor control...
  27. pmc CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior
    Roy L Silverstein
    Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA
    Sci Signal 2:re3. 2009
    ..Identification of the precise CD36 signaling pathways in specific cells elicited in response to specific ligands may yield novel targets for drug development...
  28. pmc Human behavior in Prisoner's Dilemma experiments suppresses network reciprocity
    Carlos Gracia-Lázaro
    Instituto de Biocomputación y Física de Sistemas Complejos BIFI, Universidad de Zaragoza, 50018 Zaragoza, Spain
    Sci Rep 2:325. 2012
    ..We here report that when one takes into account the real behavior of people observed in the experiments, both at the mean-field level and on utterly different networks, the ..
  29. pmc A new perspective on the role of the orbitofrontal cortex in adaptive behaviour
    Geoffrey Schoenbaum
    Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Nat Rev Neurosci 10:885-92. 2009
    ..We suggest that this function--signalling of expected outcomes--can also explain the crucial role of the OFC in changing behaviour in the face of unexpected outcomes...
  30. ncbi Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging
    Roshan Cools
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 22:4563-7. 2002
    ..Overall, these data concur with findings in rodents and nonhuman primates of reversal-learning deficits after damage to ventral frontostriatal circuitry, and also support recent clinical findings using this task...
  31. ncbi Discrete emotions predict changes in cognition, judgment, experience, behavior, and physiology: a meta-analysis of experimental emotion elicitations
    Heather C Lench
    Department of Psychology, Texas A and M University, College Station, TX 77843 4235, USA
    Psychol Bull 137:834-55. 2011
    ..was to examine the extent to which discrete emotions elicit changes in cognition, judgment, experience, behavior, and physiology; whether these changes are correlated as would be expected if emotions organize responses across ..
  32. ncbi Heart rate variability explored in the frequency domain: a tool to investigate the link between heart and behavior
    Nicola Montano
    Department of Clinical Science, Luigi Sacco Hospital, University of Milan, Milan, Italy
    Neurosci Biobehav Rev 33:71-80. 2009
  33. ncbi The microbiome-gut-brain axis: from bowel to behavior
    J F Cryan
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Neurogastroenterol Motil 23:187-92. 2011
    The ability of gut microbiota to communicate with the brain and thus modulate behavior is emerging as an exciting concept in health and disease...
  34. ncbi Detecting frontotemporal dysfunction in ALS: utility of the ALS Cognitive Behavioral Screen (ALS-CBS)
    Susan C Woolley
    Forbes Norris ALS Research Center, California Pacific Medical Center, San Francisco, California, USA
    Amyotroph Lateral Scler 11:303-11. 2010
    ..Further validation with larger sample sizes will clarify its clinical utility...
  35. pmc Daytime naps, motor memory consolidation and regionally specific sleep spindles
    Masaki Nishida
    Sleep and Neuroimaging Laboratory, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 2:e341. 2007
  36. ncbi Changing complexity in human behavior and physiology through aging and disease
    David E Vaillancourt
    Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA
    Neurobiol Aging 23:1-11. 2002
    ..It is postulated that the observed increase or decrease in complexity with aging and disease is dependent on the nature of both the intrinsic dynamics of the system and the short-term change required to realize a local task demand...
  37. pmc Habituation revisited: an updated and revised description of the behavioral characteristics of habituation
    Catharine H Rankin
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver BCV6H1B3, Canada
    Neurobiol Learn Mem 92:135-8. 2009
    ..F., & Spencer, W. A. (1966). Habituation: A model phenomenon for the study of neuronal substrates of behavior. Psychological Review, 73, 16-43]...
  38. ncbi Strategies and methods for research on sex differences in brain and behavior
    Jill B Becker
    Department of Psychology, University of Michigan, 525 East University, Ann Arbor, MI 48109, USA
    Endocrinology 146:1650-73. 2005 health and disease susceptibility, in the pharmacological effects of drugs, and in the study of brain and behavior. To investigate sex differences in brain and behavior there is a logical series of questions that should be ..
  39. ncbi Emotion, cognition, and behavior
    R J Dolan
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Science 298:1191-4. 2002
    ..The psychological consequences and mechanisms underlying the emotional modulation of cognition provide the focus of this article...
  40. ncbi Eye movements in natural behavior
    Mary Hayhoe
    Department of Brain and Cognitive Science, University of Rochester, Rochester, NY 14627, USA
    Trends Cogn Sci 9:188-94. 2005
    ..All of these advances are proving crucial for understanding how behavioral programs control the selection of visual information...
  41. ncbi Prefrontal-cingulate interactions in action monitoring
    W J Gehring
    Department of Psychology, University of Michigan, 525 East University Avenue, Ann Arbor, Michigan 48109 1109, USA
    Nat Neurosci 3:516-20. 2000
    ..Lateral prefrontal damage also affected corrective behavior. Thus the lateral prefrontal cortex seemed to interact with the anterior cingulate cortex in monitoring behavior ..
  42. pmc Serotonin selectively influences moral judgment and behavior through effects on harm aversion
    Molly J Crockett
    Department of Experimental Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Proc Natl Acad Sci U S A 107:17433-8. 2010
    Aversive emotional reactions to real or imagined social harms infuse moral judgment and motivate prosocial behavior. Here, we show that the neurotransmitter serotonin directly alters both moral judgment and behavior through increasing ..
  43. pmc Hierarchical models of behavior and prefrontal function
    Matthew M Botvinick
    Department of Psychology, Princeton Neuroscience Institute, Green Hall, Princeton, NJ 08540, USA
    Trends Cogn Sci 12:201-8. 2008
    The recognition of hierarchical structure in human behavior was one of the founding insights of the cognitive revolution...
  44. ncbi Towards a functional neuroanatomy of self processing: effects of faces and words
    T T Kircher
    Department of Psychological Medicine, Institute of Psychiatry and GKT School of Medicine, De Crespigny Park, SE5 8AF, London, UK
    Brain Res Cogn Brain Res 10:133-44. 2000
    ..The self-relevant stimuli engaged to a differential extent long term and working memory, semantic and emotional processes. We suggest that regions activated by these stimuli are engaged in self-processing...
  45. ncbi Intrinsic brain activity sets the stage for expression of motivated behavior
    Marcus E Raichle
    Department of Radiology, Washington University, St Louis, Missouri 63110, USA
    J Comp Neurol 493:167-76. 2005
    ..such constraint and potential modulation is achieved likely involves processes that emerge from the coordinated behavior of multiple brain systems, and functional brain imaging techniques such as PET and fMRI are beginning to help us ..
  46. ncbi Visceral influences on brain and behavior
    Hugo D Critchley
    Psychiatry, Brighton and Sussex Medical School, Brighton BN1 9RR, UK
    Neuron 77:624-38. 2013
    ..Here, we review the role of these pathways as sources of biases to perception, cognition, emotion, and behavior and arguably the dynamic basis to the concept of self.
  47. pmc Ghrelin influences novelty seeking behavior in rodents and men
    Caroline Hansson
    Department of Physiology Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
    PLoS ONE 7:e50409. 2012
    ..between this trait and drug and alcohol abuse, led us to hypothesize that ghrelin may influence novelty seeking behavior. To test this possibility we applied several complementary rodent models of novelty seeking behavior, i.e...
  48. pmc The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond
    Mauro W Zappaterra
    Department of Physical Medicine and Rehabilitation, VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA
    Cell Mol Life Sci 69:2863-78. 2012
    ..In this review, we will discuss the development of the choroid plexus-CSF system, and review the current literature on how the CSF actively regulates mammalian brain development, behavior, and responses to traumatic brain injury.
  49. pmc Collective behavior in the spatial spreading of obesity
    Lazaros K Gallos
    Levich Institute and Physics Department, City College of New York, New York, NY 10031, USA
    Sci Rep 2:454. 2012
    ..the weaker correlations found in the underlying population distribution indicating the presence of collective behavior, i.e., individual habits may have negligible influence in shaping the patterns of spreading...
  50. pmc Privacy-preserved behavior analysis and fall detection by an infrared ceiling sensor network
    Shuai Tao
    Division of Computer Science, Hokkaido University, Kita 8 Nishi 5, Kita ku, Sapporo 060 0808, Japan
    Sensors (Basel) 12:16920-36. 2012
    An infrared ceiling sensor network system is reported in this study to realize behavior analysis and fall detection of a single person in the home environment...
  51. ncbi Alcoholism: a systems approach from molecular physiology to addictive behavior
    Rainer Spanagel
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
    Physiol Rev 89:649-705. 2009
    ..approach is not very practical if a better understanding of the pathological processes leading to an addictive behavior is to be achieved...
  52. ncbi Changing physicians' behavior: what works and thoughts on getting more things to work
    Jeremy M Grimshaw
    Clinical Epidemiology Program, Ottawa Health Research Institute, Center for Best Practices, Institute of Population Health, University of Ottawa, Ontario
    J Contin Educ Health Prof 22:237-43. 2002
    ..Since this problem is compounded by the lack of a theoretical base for conceptualizing physician behavior change, we suggest exploring the applicability of behavioral theories to the understanding of professional ..
  53. ncbi From circuits to behavior: a bridge too far?
    Matteo Carandini
    University College London, London, UK
    Nat Neurosci 15:507-9. 2012
    Neuroscience seeks to understand how neural circuits lead to behavior. However, the gap between circuits and behavior is too wide...
  54. ncbi Causal connectivity of evolved neural networks during behavior
    Anil K Seth
    The Neurosciences Institute, 10640 John Jay Hopkins Drive, San Diego, CA 92121, USA
    Network 16:35-54. 2005
    To show how causal interactions in neural dynamics are modulated by behavior, it is valuable to analyze these interactions without perturbing or lesioning the neural mechanism...
  55. pmc HCN channels in behavior and neurological disease: too hyper or not active enough?
    Alan S Lewis
    Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Mol Cell Neurosci 46:357-67. 2011
    ..nervous system, and changes in I(h) alter cellular input-output properties and neuronal circuitry important for behavior such as learning and memory...
  56. ncbi The hippocampal learning-behavior translation and the functional significance of hippocampal dysfunction in schizophrenia
    Tobias Bast
    School of Psychology and Institute of Neuroscience, University of Nottingham, Nottingham, UK
    Curr Opin Neurobiol 21:492-501. 2011
    How is hippocampal learning, including place learning, translated into behavior? The hippocampus integrates, along its septotemporal axis, substrates of rapid place learning, including entorhinal-hippocampal connectivity, with functional ..
  57. pmc Epilepsy, cognition, and behavior: The clinical picture
    Anne T Berg
    Epilepsy Center, Northwestern Children s Memorial Hospital, Chicago, Illinois, USA
    Epilepsia 52:7-12. 2011
    ..The mounting evidence argues strongly for the recognition of epilepsy as part of a spectrum of disorders and against the notion that even uncomplicated epilepsy can a priori be considered benign...
  58. ncbi Substance use and mental health trends among U.S. military active duty personnel: key findings from the 2008 DoD Health Behavior Survey
    Robert M Bray
    RTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709 2194, USA
    Mil Med 175:390-9. 2010
    ..Examine substance use and mental health issues among U.S. military personnel...
  59. pmc Bayesian models: the structure of the world, uncertainty, behavior, and the brain
    Iris Vilares
    Departments of Physical Medicine and Rehabilitation, Physiology, and Applied Mathematics, Northwestern University, 345E Superior St Onterie, Chicago, IL 60611, USA
    Ann N Y Acad Sci 1224:22-39. 2011
    ..on humans and other animals have shown that uncertainty due to unreliable or incomplete information affects behavior. Recent studies have formalized uncertainty and asked which behaviors would minimize its effect...
  60. pmc Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults
    Julio Licinio
    Center for Pharmacogenomics, Neuropsychiatric Institute, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 1761, USA
    Proc Natl Acad Sci U S A 101:4531-6. 2004
    ..resolution of type 2 diabetes mellitus and hypogonadism, and beneficial effects on ingestive and noningestive behavior. These results highlight the role of the leptin pathway in adults with key effects on the regulation of body ..
  61. ncbi Dissociation of reward anticipation and outcome with event-related fMRI
    B Knutson
    National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892-1610, USA
    Neuroreport 12:3683-7. 2001
    ..These findings suggest that reward anticipation and outcomes may differentially recruit distinct regions that lie along the trajectory of ascending dopamine projections...
  62. pmc Predicting consumer behavior with Web search
    Sharad Goel
    Microeconomics and Social Systems, Yahoo Research, 111 West 40th Street, New York, NY 10018, USA
    Proc Natl Acad Sci U S A 107:17486-90. 2010
    ..Here we show that what consumers are searching for online can also predict their collective future behavior days or even weeks in advance...
  63. ncbi Ages for the Middle Stone Age of southern Africa: implications for human behavior and dispersal
    Zenobia Jacobs
    GeoQuEST Research Centre, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia
    Science 322:733-5. 2008
    ..Comparison with climatic records shows that these bursts of innovative behavior cannot be explained by environmental factors alone.
  64. ncbi Intra-individual variability in behavior: links to brain structure, neurotransmission and neuronal activity
    Stuart W S MacDonald
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, S 113 30 Stockholm, Sweden
    Trends Neurosci 29:474-80. 2006
  65. ncbi Environmental contaminant-mixture effects on CNS development, plasticity, and behavior
    Deanna D Wormley
    Department of Pharmacology, Meharry Medical College, Nashville, TN 37208, USA
    Toxicol Appl Pharmacol 197:49-65. 2004
    ..receptor (NMDA) mRNA expression, (3) long-term potentiation (LTP), (4) fixed-ratio performance learning behavior, and (5) experience-dependent activity related cytoskeletal-associated protein (Arc) mRNA and protein expression ..
  66. ncbi The limbic lobe and its output channels: implications for emotional functions and adaptive behavior
    Lennart Heimer
    Department of Neurosurgery and Neuroscience, University of Virginia, Box 800212, Charlottesville, VA 22908, USA
    Neurosci Biobehav Rev 30:126-47. 2006
    ..desire to move beyond the limbic system in efforts to explain key facets of emotional functions and motivational behavior. This review promotes an anatomical viewpoint, which originated as a result of histotechnical advances...
  67. pmc Adaptive human behavior in epidemiological models
    Eli P Fenichel
    School of Life Sciences and ecoSERVICES Group, Arizona State University, Tempe, AZ 85287 4501, USA
    Proc Natl Acad Sci U S A 108:6306-11. 2011
    ..policy to manage epidemics focuses on motivating people, through social distancing policies, to alter their behavior to reduce contacts and reduce public disease risk. Person-to-person contacts drive human disease dynamics...
  68. pmc Behavior-specific changes in transcriptional modules lead to distinct and predictable neurogenomic states
    Sriram Chandrasekaran
    Center for Biophysics and Computational Biology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Proc Natl Acad Sci U S A 108:18020-5. 2011
    ..853 individual honey bees exhibiting 48 distinct behavioral phenotypes in naturalistic contexts, we report that behavior-specific neurogenomic states can be inferred from the coordinated action of transcription factors (TFs) and their ..
  69. ncbi Electrophysiological correlates for response inhibition in a Go/NoGo task
    H Bokura
    Department of Internal Medicine III, Shimane Medical University, 89 1, Enya, Izumo, 693 8501, Shimane, Japan
    Clin Neurophysiol 112:2224-32. 2001
    ..Event-related brain potentials (ERPs) during a Go/NoGo task were investigated to elucidate the electrophysiological basis for executive and inhibitory control of responses...
  70. pmc Using EEG to explore how rTMS produces its effects on behavior
    Jeffrey S Johnson
    Department of Psychiatry, University of Wisconsin Madison, 53719, USA
    Brain Topogr 22:281-93. 2010
    A commonly held view is that, when delivered during the performance of a task, repetitive TMS (rTMS) influences behavior by producing transient "virtual lesions" in targeted tissue...
  71. pmc Searching for genes underlying behavior: lessons from circadian rhythms
    Joseph S Takahashi
    Howard Hughes Medical Institute, Northwestern University, Evanston, IL 60208, USA
    Science 322:909-12. 2008 gene) approaches to uncover genes that drive the molecular mechanism of circadian clocks and control circadian behavior has been unprecedented...
  72. pmc Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior
    Luc Mallet
    Institut National de la Santé et de la Recherche Médicale AVENIR Group, Behavior, Emotion, and Basal Ganglia, 75013 Paris, France
    Proc Natl Acad Sci U S A 104:10661-6. 2007
    ..This observation suggests that the STN plays a role in the control of a complex behavior that includes emotional as well as cognitive and motor components...
  73. pmc Monoamine oxidase: from genes to behavior
    J C Shih
    Department of Molecular Pharmacology and Toxicology, School of Pharmacy, University of Southern California, Los Angeles 90033, USA
    Annu Rev Neurosci 22:197-217. 1999
    ..MAO A and B knock-out mice exhibit distinct differences in neurotransmitter metabolism and behavior. MAO A knock-out mice have elevated brain levels of serotonin, norephinephrine, and dopamine and manifest ..
  74. pmc The immune system and developmental programming of brain and behavior
    Staci D Bilbo
    Department of Psychology and Neuroscience, Duke University, 572 Research Drive, Box 91050, Durham, NC 27708, USA
    Front Neuroendocrinol 33:267-86. 2012
    ..Immune molecules have a powerful impact on neuroendocrine function, including hormone-behavior interactions, during health as well as sickness...
  75. pmc Color in context: psychological context moderates the influence of red on approach- and avoidance-motivated behavior
    Brian P Meier
    Department of Psychology, Gettysburg College, Gettysburg, Pennsylvania, United States of America
    PLoS ONE 7:e40333. 2012
    ..and achievement-relevant contexts, respectively, but in all existing empirical work approach and avoidance behavior has been studied in separate tasks and separate experiments...
  76. ncbi Stochastic models of decisions about motion direction: behavior and physiology
    Jochen Ditterich
    Center for Neuroscience and Section of Neurobiology, Physiology and Behavior, University of California, Davis, CA 95616, USA
    Neural Netw 19:981-1012. 2006
    ..Overall, the data favor a diffusion model with time-variant gain and leaky integrators. The integration time constant, however, turns out not to be well-constrained by the data...
  77. pmc Oseltamivir prescription and regulatory actions vis-à-vis abnormal behavior risk in Japan: drug utilization study using a nationwide pharmacy database
    Hisashi Urushihara
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan
    PLoS ONE 6:e28483. 2011
    ..issued in Japan to restrict oseltamivir use in children aged 10-19 years because of safety concerns over abnormal behavior. The effectiveness and validity of regulatory risk minimization actions remain to be reviewed, despite their ..
  78. pmc From men to mice: CHRNA5/CHRNA3, smoking behavior and disease
    Jennifer J Ware
    Department of Psychological Medicine, Cardiff University, 1st Floor Neuadd Meirionnydd, Heath Park Campus, Cardiff CF14 4YS, United Kingdom
    Nicotine Tob Res 14:1291-9. 2012
    ..Two highly correlated single nucleotide polymorphisms (SNPs) within this region--rs16969968 in CHRNA5 and rs1051730 in CHRNA3--have generated particular interest...
  79. pmc Time scale hierarchies in the functional organization of complex behaviors
    Dionysios Perdikis
    Theoretical Neuroscience Group, UMR6233, Institut Science du Mouvement, University of the Mediterranean, Marseille, France
    PLoS Comput Biol 7:e1002198. 2011
    ..e., not from trajectories in phase space or time)...
  80. pmc A role for WNT/β-catenin signaling in the neural mechanisms of behavior
    Kimberly A Maguschak
    Massachusetts Institute of Technology, Cambridge, MA, USA
    J Neuroimmune Pharmacol 7:763-73. 2012
    ..Here we summarize the role of Wnt/β-catenin signaling in the postnatal brain and discuss recent studies suggesting that deregulated Wnt signaling can result in altered behavior and cognitive disorders.
  81. pmc Do parents recognize autistic deviant behavior long before diagnosis? Taking into account interaction using computational methods
    Catherine Saint-Georges
    Department of Child and Adolescent Psychiatry, AP HP, Groupe Hospitalier Pitie Salpetriere, Universite Pierre et Marie Curie, Paris, France
    PLoS ONE 6:e22393. 2011
  82. ncbi Modeling dad: animal models of paternal behavior
    Amanda C Kentner
    Hotckiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
    Neurosci Biobehav Rev 34:438-51. 2010
    ..on the interactions between mothers and offspring, with little research directed at understanding paternal behavior. In animal studies, experimenters correlate paternal behaviors with those seen in rodent or primate mothers, ..
  83. ncbi Early-childhood poverty and adult attainment, behavior, and health
    Greg J Duncan
    Department of Education, University of California Irvine, Irvine, CA 92697, USA
    Child Dev 81:306-25. 2010
    ..of poverty between a child's prenatal year and 5th birthday for several adult achievement, health, and behavior outcomes, measured as late as age 37...
  84. ncbi DNA methylation, behavior and early life adversity
    Moshe Szyf
    Department of Pharmacology and Therapeutics, McGill University, 3655 Sir William Osler Promenade, Montreal, Quebec H3G 1Y6, Canada
    J Genet Genomics 40:331-8. 2013
    ..Particularly important is the environment early in life including both the prenatal and postnatal social environments. ..
  85. pmc The genetics of sex differences in brain and behavior
    Tuck C Ngun
    David Geffen School of Medicine at UCLA, Gonda Center, Room 5506, 695 Charles Young Drive South, Los Angeles, CA 90095 7088, United States
    Front Neuroendocrinol 32:227-46. 2011
    ..Ultimately, the study of the biological basis for sex differences will improve healthcare for both men and women...
  86. pmc Calculating consequences: brain systems that encode the causal effects of actions
    Saori C Tanaka
    Division of the Humanities and Social Sciences and Computation and Neural Systems Program, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 28:6750-5. 2008
    ..These results reveal the involvement of distinct brain regions in the computational processes that establish the causal efficacy of actions, providing insight into the neural mechanisms underlying the adaptive control of behavior.
  87. ncbi Dynamic interaction of object- and space-based attention in retinotopic visual areas
    Notger G Müller
    Cognitive Neurology Unit, Department of Neurology, Johann Wolfgang Goethe University, 60590 Frankfurt am Main, Germany
    J Neurosci 23:9812-6. 2003
    ..Objects, hence, also guide spatial search, and this may account for the behaviorally observed delay in processing parts of an unattended object...
  88. ncbi Simple sequence repeats: genetic modulators of brain function and behavior
    John W Fondon
    McDermott Center for Human Growth and Development and Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Trends Neurosci 31:328-34. 2008
    ..SSRs can affect neuronal differentiation, brain development and even behavioral evolution...
  89. pmc Of mice and men--universality and breakdown of behavioral organization
    Toru Nakamura
    The Center for Advanced Medical Engineering and Informatics, Osaka University, Osaka, Japan
    PLoS ONE 3:e2050. 2008
  90. ncbi Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids
    Parris M Kidd
    University of California, Berkeley, California, USA
    Altern Med Rev 12:207-27. 2007
    ..DHA is proven essential to pre- and postnatal brain development, whereas EPA seems more influential on behavior and mood. Both DHA and EPA generate neuroprotective metabolites...
  91. ncbi New lower nicotine cigarettes can produce compensatory smoking and increased carbon monoxide exposure
    Andrew A Strasser
    Transdisciplinary Tobacco Use Research Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, United States
    Drug Alcohol Depend 86:294-300. 2007
    ..low nicotine cigarettes suggests smokers will compensate for lower nicotine delivery by increasing their puffing behavior to extract more nicotine...
  92. ncbi Forming attitudes that predict future behavior: a meta-analysis of the attitude-behavior relation
    Laura R Glasman
    Department of Psychology, University of Florida, Gainesville, FL 32611, USA
    Psychol Bull 132:778-822. 2006
    ..influence of factors present at the time an attitude is formed on the degree to which this attitude guides future behavior. The findings indicated that attitudes correlated with a future behavior more strongly when they were easy to ..
  93. pmc Human category learning 2.0
    F Gregory Ashby
    Department of Psychology, University of California Santa Barbara, CA 93106, USA
    Ann N Y Acad Sci 1224:147-61. 2011
    ..covered include (1) How do the various systems interact? (2) Are there different neural systems for categorization and category representation? (3) How does automaticity develop in each system? and (4) Exactly how does each system learn?..
  94. pmc Economic games on the internet: the effect of $1 stakes
    Ofra Amir
    Department of Information Systems Engineering, Ben Gurion University of the Negev, Be er Sheva, Israel
    PLoS ONE 7:e31461. 2012
    ..Using Mturk, we recruited 756 subjects and examined their behavior in four canonical economic games, with two payoff conditions each: a stakes condition, in which subjects' ..
  95. pmc The shift from local to global visual processing in 6-year-old children is associated with grey matter loss
    Nicolas Poirel
    UMR 6232, CI NAPS, CNRS, CEA, Caen University and Paris Descartes University, Sorbonne, France
    PLoS ONE 6:e20879. 2011
    ..The brain regions involved in this shift in visual preference have not been described...
  96. ncbi Motivation of extended behaviors by anterior cingulate cortex
    Clay B Holroyd
    Department of Psychology, University of Victoria, P O Box 3050 Victoria, BC V8W 3P5, Canada
    Trends Cogn Sci 16:122-8. 2012
    ..has emerged between neuropsychological theories suggesting a primary role for ACC in motivating or 'energizing' behavior, and neuroimaging-inspired theories emphasizing its contribution to cognitive control and reinforcement learning...
  97. pmc Tracking the unconscious generation of free decisions using ultra-high field fMRI
    Stefan Bode
    Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
    PLoS ONE 6:e21612. 2011
    ..These results give further evidence that FPC stands at the top of the prefrontal executive hierarchy in the unconscious generation of free decisions...
  98. pmc Multisensory guidance of orienting behavior
    Joost X Maier
    Center for Cognitive Neuroscience, Department of Neurobiology, Department of Psychology and Neuroscience, Duke University, LSRC B203, Durham NC 27708, USA
    Hear Res 258:106-12. 2009
    ..A common view is that the brain needs to reconcile these differences in order to control behavior, such as orienting gaze to the location of a sound source...
  99. ncbi Fetal behavior
    Jan G Nijhuis
    Department of Obstetrics and Gynecology, Academic Hospital Maastricht, P O Box 5800, 6202 AZ Maastricht, The Netherlands
    Neurobiol Aging 24:S41-6; discussion S47-9, S51-2. 2003
    Fetal behavior reflects the activity of the fetal central nervous system (CNS). Insight in fetal behavior is crucial for the understanding of normal fetal well-being and in the evaluation of the possibly compromised fetus...
  100. pmc The time course of the influence of valence and arousal on the implicit processing of affective pictures
    Chunliang Feng
    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    PLoS ONE 7:e29668. 2012
    ..Our results suggest that valence and arousal effects on implicit affective processing are more complicated than previous ERP studies with explicit tasks have revealed...
  101. ncbi Episodic memory in frontotemporal dementia: a critical review
    Michael Hornberger
    Neuroscience Research Australia, Sydney, NSW 2031, Australia
    Brain 135:678-92. 2012
    ..Together, recent clinical and experimental findings and the historical evidence represent a strong case for a re-evaluation of the importance of memory disturbance in the clinical diagnosis of frontotemporal dementia...

Research Grants80

  1. Acceptance and Commitment Therapy as a Treatment for OCD
    Steven Hayes; Fiscal Year: 2007
    ..Instead, it focuses on stepping back from ones obsessions and focusing behavior change on following ones values rather than decreasing uncomfortable private events such as anxiety or obsessions...
  2. Cannabinoid Receptor Function in Alcoholism: Effects of D-9-THC
    DEEPAK D SOUZA; Fiscal Year: 2008
    ..lower levels of alcohol preference and consumption, 2) slower rate of acquisition of alcohol drinking behavior, 3) lower alcohol sensitivity, and 4) blunted alcohol-induced dopamine release in the nucleus accumbens...
  3. Cannabinoids, Neural Synchrony and Information Processing
    DEEPAK D SOUZA; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
    DEEPAK D SOUZA; Fiscal Year: 2002
    ..Pilot data (n=12) towards this proposal suggests that glycine reduces ketamine-induced perceptual alterations, negative symptoms and impairments on recall without worsening positive symptoms. ..
    DEEPAK D SOUZA; Fiscal Year: 2009
  6. Linking Affect to Action: Critical Contributions of the Orbitofrontal Cortex
    Geoffrey Schoenbaum; Fiscal Year: 2006
    ..The participation of minorities and women has been emphasized at each level (organizers, speakers, students). Thus the conference will address important scientific, social, and educational issues. [unreadable] [unreadable] [unreadable]..
  7. Pathology and Treatment of Cytokine-Induced Depression
    Andrew Miller; Fiscal Year: 2008
    ..Proinflammatory cytokines have been found to influence neurobiologic function including neurochemistry and behavior, and induce a depressive syndrome that has overlapping features with major depression...
  8. Reward System Recovery Following Behavioral Activation Therapy in Depression
    GABRIEL DICHTER; Fiscal Year: 2007
    ..Such a strategy is consistent with NIMH's mission to reduce the burden of psychiatric disorders. [unreadable] [unreadable] [unreadable]..
  9. Maternal Opioid Treatment: Human Experimental Research
    Barry Lester; Fiscal Year: 2009
    ..abstract_text> ..
  10. Rapid Effects of Estradiol in the Brain
    Jill Becker; Fiscal Year: 2007
    ..It may also be important for our understanding and treatment of a number of neurological disorders including stroke, Alzheimer's disease and Parkinson's disease where estradiol may be neuroprotective. ..
    J A Scott Kelso; Fiscal Year: 2006
    unreadable] DESCRIPTION (provided by applicant): All cognition and behavior, from perception and memory to decision-making and action, requires the activation of specialized areas in the brain as well as the means to globally coordinate ..
  12. Mechanisms of Radiation Induced Fatigue in Cancer
    Julienne Bower; Fiscal Year: 2006
    ..Together with a targeted program of didactic instruction, this project will prepare the candidate to become a fully independent behavioral scientist in the field of cancer prevention and control research. ..
  13. Steroid Hormones Regulatory Mechanisms and Behavior
    SHAILAJA MANI; Fiscal Year: 2006
    ..regulate cellular functions in the central nervous system resulting in changes in physiology and reproductive behavior in a variety of species...
  14. Psychoneuroimmunology and Mind-Body Interventions
    Janice Kiecolt Glaser; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  15. College Drinking: A Twin Study
    Andrey Anokhin; Fiscal Year: 2006
    ..the effects of transition to college and, alternatively, entry into workforce on changes in drinking behavior; (2) to determine, using family-based non-collegiate controls, the relative role of dispositional (pre-existing) ..
  16. Neural Mechanisms of MTBI: A Prospective fMRI Approach
    J A Scott Kelso; Fiscal Year: 2008
    ..This individualized approach should provide important insights into the structural and dynamic mechanisms underlying recovery of function in the human brain. ..
  17. Pathophysiology of IFN-alpha-induced Sleep Disturbances
    Andrew Miller; Fiscal Year: 2008
    ..Moreover, this work will identify novel targets for the development of treatment strategies for sleep alterations in medically ill patients. ..
  18. Fetal and Infant Neurobehavior in Opiate Dependent Women
    Lauren Jansson; Fiscal Year: 2009
    ..Information gained from this proposal has the potential to significantly impact the way in which we treat the difficult and high-risk population of opiate dependent pregnant women. ..
  19. Hormones Neuronal Phosphoproteins and Behavior
    SHAILAJA MANI; Fiscal Year: 2008
    ..regulate functions in the central nervous system resulting in alterations in physiology and reproductive behavior. One means by which estradiol and progesterone exert their neural effects on reproductive behavior is via their ..
  20. Nursing Home Pain Management Algorithm Clinical Trial
    Mary Ersek; Fiscal Year: 2009
    ..Findings from this study will assist NH staff to assess and treat pain effectively in cognitively intact and impaired residents. Long-term follow-up will establish the persistence of changes in clinical practice and resident outcomes. ..
  21. Behavioral factors in the surgical treatment of obesity
    Thomas Wadden; Fiscal Year: 2009
    ..The study, by examining ghrelin and other appetite-related hormones, also will enhance knowledge of the regulation of body weight following GBP. ..
  22. Development of Basic Components of Decision Making
    BETTY CASEY; Fiscal Year: 2008
    ..The proposed studies are in response to RFA # DA-04-009 Behavioral and Cognitive Processes Related to Adolescent Drug Abuse. ..
  23. Mental Health Conferences: Comparative & Primate Studies
    Judy Cameron; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  24. Drug Effects on Behavior: Workplace Implications
    Carl Hart; Fiscal Year: 2008
    ..Together, the data from the proposed studies will have substantial public health impact and will serve both educational and public policy functions. ..
  25. The Functional Neuroanatomy of Acute Nicotinic Modulation of Impulsivity in Women
    Alexandra Potter; Fiscal Year: 2008
    ..This model may be useful for the examination of other drugs of abuse. [unreadable] [unreadable] [unreadable]..
  26. Genes Influencing Social Behaviors
    DONALD WELLS PFAFF; Fiscal Year: 2010
    ..with all interesting results followed up by a novel antisense DNA technique - and measure an interesting behavior maternal aggression (as part of reproduction), compared to an 'affiliative behavior', maternal care ..
  27. Brain Development Following Institutionalization
    BETTY CASEY; Fiscal Year: 2008
    ..We will recruit a typically developing population of children to assess deviations or delays in the development of amygdala and hippocampal volume and function. [unreadable] [unreadable]..
  28. Errors and Expectancies in OFC and VTA and their Roles in Associative Learning
    GEOFFREY M SCHOENBAUM; Fiscal Year: 2010
    ..This proposal will test this hypothesis, using inactivation and single-unit recording to ask how OFC is involved learning and in the calculation of prediction errors in dopaminergic VTA neurons during Pavlovian blocking. ..
  29. Long-Term Outcomes of Childhood-Onset Epilepsy
    Anne Berg; Fiscal Year: 2006
    ..This in turn could help lessen the burdens associated with childhood-and adolescent-onset epilepsy for the individual, the family, and society as a whole. ..
  30. Development of Prediction and Reward Related Circuitry
    BETTY CASEY; Fiscal Year: 2004 R21 application in response to RFA DA-02-001 entitled "Neuroimaging Technology Development to Assess Brain and Behavior in Pediatric Populations"...
  31. Intranasal Methamphetamine: A Pharmacotherapy Model
    Carl Hart; Fiscal Year: 2009
    Thomas Wadden; Fiscal Year: 2003
    ..The predicted superiority of lifestyle activity is based on extensive pilot data and, if confirmed, should significantly improve the management of obesity and its associated health complications. ..
    Andrew Miller; Fiscal Year: 2002
    ..Taken together, these studies will provide the foundation for developing new treatment strategies for immunomodulation drawing upon advances in neuroendocrinology and the neurosciences. ..
    David Crews; Fiscal Year: 2002
    ..temperature have been found in morphology, secretion of and sensitivity to steroid hormones, sociosexual behavior, reproductive success, and in the neuroanatomy and metabolic activity of brain areas that mediate sociosexual ..
    Lauren Jansson; Fiscal Year: 2004
    ..Upon completing the 5-year funding period, Dr. Jansson plans to have written an RO1 grant application to pursue research ideas identified during KO8 funding. ..
  36. Chronic Pain Self-Management for the Elderly
    Mary Ersek; Fiscal Year: 2005
    ..abstract_text> ..
    Hal Blumenfeld; Fiscal Year: 2002
    ..The information provided by these studies may yield insights into the mechanisms of normal cortical rhythmic oscillations, and suggest new therapies for the therapeutic management of epileptic seizures. ..
  38. Psychoneuroimmunology and Mind-Body Medicine
    Janice Kiecolt Glaser; Fiscal Year: 2005
    ..Accordingly, a psychoneuroimmunology focus for these mechanistic studies will provide a way to clarify mechanisms while assessing clinical efficacy. ..
  39. Interaction of Brain Norepinephrine/Galanin in Stress
    David Morilak; Fiscal Year: 2005
    ..abstract_text> ..
  40. Symposium on Challenging Behavior in CHARGE Syndrome
    TIMOTHY HARTSHORNE; Fiscal Year: 2003
    ..One issue that has been of considerable concern to parents is the development of severe behavior problems...
    Andrey Anokhin; Fiscal Year: 2005
    ..Although a strong genetic contribution to smoking behavior has been well documented by recent studies, little is known about biobehavioral mechanisms that might mediate ..
    Thomas Wadden; Fiscal Year: 2002
    ..b>Behavior therapy facilitates adherence to exercise and medication recommendations, whereas pharmacotherapy, by reducing ..
    Donald Pfaff; Fiscal Year: 2002
    The most advanced system for understanding neural and molecular mechanisms of mammalian behavior is the effect of estradiol (E) on lordosis behavior by the female rat upon mounting by the male...
    Andrew Miller; Fiscal Year: 2003
    ..interferon a (IFNa) to humans has been shown to induce a depression-like syndrome, also referred to as "sickness behavior," that includes symptoms of depressed mood, anhedonia, anorexia, fatigue, and disrupted sleep...
    Andrew Miller; Fiscal Year: 2003
    ..into an examination of the impact of the type I interferon (IFN), IFNalpha, on neuroendocrine function and behavior in patients undergoing high dose IFNalpha therapy for malignant melanoma...
    Andrew Miller; Fiscal Year: 2008
    ..unreadable] [unreadable]..
    David Crews; Fiscal Year: 2003
    ..grant at the University of Texas at Austin focusing on interdisciplinary training in the biological bases of behavior. A small select group of behavioral neuroscientists from the Psychology and Zoology departments of the University ..
  48. Functional neuroanatomical deficits in ADHD families
    BETTY CASEY; Fiscal Year: 2003
    ..Imaging will be performed at corresponding imaging sites at DUMC, Weill Medical College of Cornell University, and Stanford University respectively. ..
    David Crews; Fiscal Year: 2009
    ..on androgens in all vertebrates studied, but the mechanisms by which these hormones influence the brain and behavior are not well understood...
    Timothy Monk; Fiscal Year: 2001
  51. Drug Abuse: Sex differences in developmental and environmental influences
    Jill B Becker; Fiscal Year: 2010
    ..the consequences for both sexes is an enhanced response to cocaine which increases vulnerability for drug taking behavior. Prenatal stress exposes the developing organism to increased levels of glucocorticoids at a time during which ..
  52. Cholinergic Effects on Inhibition and Delay in ADHD
    Alexandra Potter; Fiscal Year: 2005
    ..Recent evidence suggests that two models of the cognitive underpinnings of impulsive behavior, the behavioral inhibition model (Bl) and the delay aversion (DA) model, contribute independently to ADHD ..
  53. Frontostriatal Development and Cognitive Control
    BETTY CASEY; Fiscal Year: 2005
    DESCRIPTION: One key feature of cognitive and behavioral development is the gradual ability to override one behavior in favor of another or to suppress attention to irrelevant information in favor of more relevant information...
  54. Cognitive and Emotional Processes in Decision-Making
    ALAN SANFEY; Fiscal Year: 2007
    ..field of neuroeconomics, which attempts understand the component processes of decision-making by examining both behavior and the underlying neural substrates...
  55. 2007 Catecholamines Gordon Research Conference
    Jill Becker; Fiscal Year: 2007
    ..applicant): Catecholamines are investigated using a broad range of approaches: molecular biology, simple systems, behavior and clinical studies...
  56. Resilience in Children
    Barry Lester; Fiscal Year: 2006
    ..C. The conference is being organized by Barry M. Lester, Ph.D., Professor of Psychiatry & Human Behavior and Pediatrics, and Director, Infant Development Center, Brown Medical School...
  57. Exercise Effects on the Primate Nigrostriatal Pathway
    Judy Cameron; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  58. The effects of SAMe on reward circuitry in depression
    Diego Pizzagalli; Fiscal Year: 2007
    ..A better understanding of the mechanisms of actions of SAMe should, in turn, provide a foundation for future clinical trials. ..
  59. Neuroimmune Mechanisms of Glucocorticoid Resistance
    Andrew H Miller; Fiscal Year: 2010
    ..Taken together, these studies will help identify novel targets for the treatment of mood disorders in both medically ill and medically healthy patients. ..
  60. Preventing spike-wave epileptogenesis: critical periods & neuroimaging biomarkers
    Hal Blumenfeld; Fiscal Year: 2010
    ..untreated animals. We will also investigate the anatomical basis of white matter DTI abnormalities through electron microscopy to determine changes in axons and myelin in affected regions. 2. ..
    Robert Findling; Fiscal Year: 2005
    ..This study will provide information about the comparative effectiveness of the most commonly used and representative antipsychotic drugs in youth with schizophrenia spectrum disorders. ..
  62. Human Laboratory Model of Cocaine Treatment: Behavioral Economic Analysis
    Mark K Greenwald; Fiscal Year: 2010
    ..Therefore, tests of cocaine medications need to be conducted in synchrony with behavior therapies also taking into account individual differences in order to understand the mechanisms of interaction ..
  63. Fronto-Striatal Dysfunction in IFNa-Induced Depression
    Andrew Miller; Fiscal Year: 2008
    ..Proinflammatory cytokines have been found to influence neurobiologic function including neurochemistry and behavior, and induce a depressive syndrome that has overlapping features with major depression...
    Sandra Comer; Fiscal Year: 2002
  65. Adolescence: A Sensitive Period for Nicotine Addiction
    Edward Levin; Fiscal Year: 2008
    ..unreadable] [unreadable]..
    CAROLYN MERVIS; Fiscal Year: 2009
    ..tests of language, memory, and visuospatial abilities;and measures of personality, temperament, and adaptive behavior. 3) Identify genes responsible for specific phenotypic features of WS...
  67. MCH Modulation of Neurotransmission in the LH area
    Xiao Bing Gao; Fiscal Year: 2005
    ..The funding of this research proposal is important for the applicant to continue this course. A career development plan is also documented in this proposal. ..
    Carl Latkin; Fiscal Year: 2002
    ..sequelae, STIs are risk factors for HIV infection and transmission, are biological markers of HIV-related sexual behavior, and help validate self-reports of risk behaviors...
  69. BOLD fMRI in MR research to map learning histories
    MICHAEL SCHLUND; Fiscal Year: 2004
    ..abstract_text> ..
  70. Opioid Antagonist Discrimination: A Model of Withdrawal
    Alison Oliveto; Fiscal Year: 2011
    ..This paradigm provides a sensitive, standard, objective, systematic method to identify potential agents for enhancing OW treatment which can be examined further in a detox protocol. ..
    Ralph Sacco; Fiscal Year: 2007
    ..abstract_text> ..
  72. Behavioral Effects of GHB in Healthy Volunteers
    ALISON OLIVETO BEAUDOIN; Fiscal Year: 2003
    ..This study will also potentially establish a standard methodology to characterize systematically the behavioral effects of GHB in humans. ..
  73. Conduct Disorder and Depression in Childhood
    Theodore Beauchaine; Fiscal Year: 2006
    ..Findings obtained should further our understanding of the autonomic substrates of CD, depression, and their comorbidity, and may have differential treatment implications for depressed probands who do and do not present with comorbid CD. ..
  74. Role of Kv3 Potassium Channels in Arousal-State Dynamics
    Rolf Joho; Fiscal Year: 2008
    ..altered neuronal firing patterns in distinct neuronal subpopulations with the correspondingly altered sleep-wake behavior. Hence, Kv3 mutant mice will serve as well-defined models to study the pathophysiology of hyperactivity and sleep ..
  75. Tailored Activity to Improve Affect in Dementia at Home
    Laura Gitlin; Fiscal Year: 2006
    ..This pilot study will provide critical data by which to refine and standardize the intervention manual and protocols, and structure the design of a large-scale randomized clinical trial. ..
    Roger Ratcliff; Fiscal Year: 2003
    ..The second aim of the research is to investigate the joint behavior of small subsets of the neuronal populations that decide the direction, distance, and timing of eye movements...
  77. Hypothalamic Leptin and Insulin Signaling
    Christopher Morrison; Fiscal Year: 2007
    ..that leptin is capable of acting in either the forebrain (hypothalamus) or hindbrain to regulate feeding behavior. However, the relative importance of these 2 areas in sensing changes in circulating leptin is poorly ..
  78. Advanced Reproductive Age and Environmental Health
    Stephanie Engel; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  79. Vagal Tone and Social Behaviors in Autism
    STEPHEN SHEINKOPF; Fiscal Year: 2004
    ..This study may provide information on the biological basis of the social deficits in autism and may also help develop methods that can be used to study autism in infancy. ..
  80. Wise Mind: Environmental Approach for Obesity Prevention
    Donald Williamson; Fiscal Year: 2004
    ..abstract_text> ..