reference values

Summary

Summary: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.

Top Publications

  1. pmc Establishing a standard definition for child overweight and obesity worldwide: international survey
    T J Cole
    Department of Epidemiology and Public Health, Institute of Child Health, London WC1N 1EH
    BMJ 320:1240-3. 2000
  2. ncbi Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values
    R Rolke
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Mainz, Germany
    Pain 123:231-43. 2006
  3. ncbi Evaluation of diffuse myocardial fibrosis in heart failure with cardiac magnetic resonance contrast-enhanced T1 mapping
    Leah Iles
    Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    J Am Coll Cardiol 52:1574-80. 2008
  4. ncbi Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
    Struan F A Grant
    deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
    Nat Genet 38:320-3. 2006
  5. ncbi A new and improved population-based Canadian reference for birth weight for gestational age
    M S Kramer
    Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Canada
    Pediatrics 108:E35. 2001
  6. ncbi Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
    Xinmei Zhang
    Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China
    Diabetes 57:1246-53. 2008
  7. ncbi Human hydration indices: acute and longitudinal reference values
    Lawrence E Armstrong
    Human Performance Laboratory, University of Connecticut, Storrs, CT, USA
    Int J Sport Nutr Exerc Metab 20:145-53. 2010
  8. ncbi Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program
    Gary L Myers
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Clin Chem 52:5-18. 2006
  9. ncbi Gamma glutamyl transferase
    J B Whitfield
    Department of Clinical Biochemistry, Royal Prince Alfred Hospital, and University of Sydney, NSW, Australia
    Crit Rev Clin Lab Sci 38:263-355. 2001
  10. ncbi Sleep duration from infancy to adolescence: reference values and generational trends
    Ivo Iglowstein
    Growth and Development Center, University Children s Hospital, Zurich, Switzerland
    Pediatrics 111:302-7. 2003

Detail Information

Publications288 found, 100 shown here

  1. pmc Establishing a standard definition for child overweight and obesity worldwide: international survey
    T J Cole
    Department of Epidemiology and Public Health, Institute of Child Health, London WC1N 1EH
    BMJ 320:1240-3. 2000
    ..To develop an internationally acceptable definition of child overweight and obesity, specifying the measurement, the reference population, and the age and sex specific cut off points...
  2. ncbi Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values
    R Rolke
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Mainz, Germany
    Pain 123:231-43. 2006
    ..plus or minus signs in patients we have now established age- and gender-matched absolute and relative QST reference values from 180 healthy subjects, assessed bilaterally over face, hand and foot...
  3. ncbi Evaluation of diffuse myocardial fibrosis in heart failure with cardiac magnetic resonance contrast-enhanced T1 mapping
    Leah Iles
    Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    J Am Coll Cardiol 52:1574-80. 2008
    ..The purpose of this study was to investigate a noninvasive method for quantifying diffuse myocardial fibrosis with cardiac magnetic resonance imaging (CMRI)...
  4. ncbi Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
    Struan F A Grant
    deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
    Nat Genet 38:320-3. 2006
    ..It is thought to act through regulation of proglucagon gene expression in enteroendocrine cells via the Wnt signaling pathway...
  5. ncbi A new and improved population-based Canadian reference for birth weight for gestational age
    M S Kramer
    Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Canada
    Pediatrics 108:E35. 2001
    ....
  6. ncbi Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
    Xinmei Zhang
    Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China
    Diabetes 57:1246-53. 2008
    ..This study aimed to investigate the relationship between its serum levels and various cardiometabolic parameters in humans...
  7. ncbi Human hydration indices: acute and longitudinal reference values
    Lawrence E Armstrong
    Human Performance Laboratory, University of Connecticut, Storrs, CT, USA
    Int J Sport Nutr Exerc Metab 20:145-53. 2010
    ..This investigation provided reference values for euhydration (i.e...
  8. ncbi Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program
    Gary L Myers
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Clin Chem 52:5-18. 2006
    ..Available resources for standardization of serum creatinine measurement are discussed, and recommendations for measurement improvement are given...
  9. ncbi Gamma glutamyl transferase
    J B Whitfield
    Department of Clinical Biochemistry, Royal Prince Alfred Hospital, and University of Sydney, NSW, Australia
    Crit Rev Clin Lab Sci 38:263-355. 2001
    ....
  10. ncbi Sleep duration from infancy to adolescence: reference values and generational trends
    Ivo Iglowstein
    Growth and Development Center, University Children s Hospital, Zurich, Switzerland
    Pediatrics 111:302-7. 2003
    ....
  11. ncbi Normal fasting plasma glucose levels and type 2 diabetes in young men
    Amir Tirosh
    Medical Corps Headquarters, Tel Hashomer, Israel
    N Engl J Med 353:1454-62. 2005
    ..55 mmol per liter). Whether higher fasting plasma glucose levels within this range independently predict type 2 diabetes in young adults is unclear...
  12. ncbi Serum insulin-like growth factor I reference values for an automated chemiluminescence immunoassay system: results from a multicenter study
    Georg Brabant
    Department of Gastroenterology, Hepatology and Endocrinology, Medizinische Hochschule, Hannover, Germany
    Horm Res 60:53-60. 2003
    ..The objective of the present study was to develop cross-sectional reference values for S-IGF-I measured by an automated chemiluminescence immunoassay (Nichols Advantage).
  13. ncbi Tensorial extensions of independent component analysis for multisubject FMRI analysis
    C F Beckmann
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Neuroimage 25:294-311. 2005
    ....
  14. ncbi World Health Organization reference values for human semen characteristics
    Trevor G Cooper
    Centre of Reproductive Medicine and Andrology of the University, Domagkstrasse 11, Munster, Germany
    Hum Reprod Update 16:231-45. 2010
    ..Reference intervals for values of semen parameters from a fertile population could provide data from which prognosis of fertility or diagnosis of infertility can be extrapolated...
  15. ncbi Human myocardium: single-breath-hold MR T1 mapping with high spatial resolution--reproducibility study
    Daniel R Messroghli
    BHF Cardiac MRI Unit, Leeds General Infirmary, England
    Radiology 238:1004-12. 2006
    ..This technique could enable direct quantification of changes in tissue characteristics in ischemic and inflammatory myocardial diseases...
  16. pmc Dual energy X-Ray absorptiometry body composition reference values from NHANES
    Thomas L Kelly
    Hologic, Inc, Bedford, Massachusetts, USA
    PLoS ONE 4:e7038. 2009
    ..fat mass ratio of fat, bone mineral content (BMC) and bone mineral density (BMD) were analyzed to provide reference values for subjects 8 to 85 years old...
  17. ncbi Reference values for the timed up and go test: a descriptive meta-analysis
    Richard W Bohannon
    Neag School of Education, University of Connecticut, Storrs, CT, USA
    J Geriatr Phys Ther 29:64-8. 2006
    The Timed Up and Go (TUG) test is widely employed in the examination of elders, but definitive normative reference values are lacking. This meta-analysis provided such values by consolidating data from multiple studies.
  18. ncbi Clinical applications of arterial stiffness; definitions and reference values
    Michael F O'Rourke
    St Vincent s Hospital UNSW and St Vincent s Clinic, Sydney, Australia
    Am J Hypertens 15:426-44. 2002
    ..E. Safar and E.D. Frohlich...
  19. ncbi Australian national birthweight percentiles by gestational age
    C L Roberts
    NSW Centre for Perinatal Health Services Research, Department of Obstetrics and Gynaecology, University of Sydney
    Med J Aust 170:114-8. 1999
    ..To develop national birthweight percentiles by gestational age for male and female singleton infants born in Australia, and to compare the birthweight percentiles of Indigenous and non-Indigenous infants...
  20. pmc Immunohematological reference ranges for adult Ethiopians
    A Tsegaye
    Ethiopian Netherlands AIDS Research Project, Ethiopian Health and Nutrition Research Institute, Addis Ababa, Ethiopia
    Clin Diagn Lab Immunol 6:410-4. 1999
    ..i) The WBC and platelet values of healthy HIV-negative Ethiopians are lower than the adopted reference values of Ethiopia...
  21. ncbi Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
    Shelley Lindley
    Department of Immunobiology, Guy s, King s and St Thomas School of Medicine, 2nd Floor, New Guy s House, Guy s Hospital London SE1 9RT, UK
    Diabetes 54:92-9. 2005
    ..007) and intracellular CTLA-4 (P = 0.01). These data demonstrate deficiency in function of the CD4(+)CD25(+) Treg population that may influence the pathogenesis of type 1 diabetes...
  22. ncbi Prediction equations for normal and low lung function from the Health Survey for England
    E Falaschetti
    Dept of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    Eur Respir J 23:456-63. 2004
    ..It is, therefore, suggested that these newly developed prediction equations be used for the White English population in both epidemiological studies and clinical practice...
  23. pmc Immunohaematological reference values in human immunodeficiency virus-negative adolescent and adults in rural northern Tanzania
    Bernard J Ngowi
    Haydom Lutheran Hospital, Mbulu District, Manyara Region, Tanzania
    BMC Infect Dis 9:1. 2009
    ..The aim of this study was to determine normal reference values for CD4 T cells, lymphocytes, leucocytes and haemoglobin level in healthy, HIV negative adolescents and ..
  24. pmc Population-based hematologic and immunologic reference values for a healthy Ugandan population
    Eric S Lugada
    Center for International Health, University of Bergen, Bergen, Norway
    Clin Diagn Lab Immunol 11:29-34. 2004
    To assess the validity of the reference values for hematologic and immunologic indices currently used in Africa, we evaluated blood samples from 3,311 human immunodeficiency virus (HIV)-negative Ugandans aged 1 week to 92 years...
  25. pmc Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
    K Huhtinen
    Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland
    Br J Cancer 100:1315-9. 2009
    ..Taken together, measuring both HE4 and CA125 serum concentrations increases the accuracy of ovarian cancer diagnosis and provides valuable information to discriminate ovarian tumours from ovarian endometriotic cysts...
  26. ncbi National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers
    Catharine M Sturgeon
    Department of Clinical Biochemistry, Royal Infirmary of Edinburgh, Edinburgh, UK
    Clin Chem 54:e11-79. 2008
    ..Updated National Academy of Clinical Biochemistry (NACB) Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been developed...
  27. ncbi Body mass index reference values (mean and SD) for Swedish children
    J Karlberg
    Clinical Trials Centre and Department of Pediatrics, University of Hong Kong, Hong Kong SAR, PR China
    Acta Paediatr 90:1427-34. 2001
    ..Many studies have been done to present BMI reference values in centile values rather than mean and SD values since its statistical distribution is positively skewed...
  28. ncbi Increased fetal adiposity: a very sensitive marker of abnormal in utero development
    Patrick M Catalano
    Department of Reproductive Biology, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH 44109, USA
    Am J Obstet Gynecol 189:1698-704. 2003
    ....
  29. pmc Normal macular thickness measurements in healthy eyes using Stratus optical coherence tomography
    Annie Chan
    New England Eye Center, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Mass 02111 1533, USA
    Arch Ophthalmol 124:193-8. 2006
    ..To report normal macular thickness measurements in healthy eyes using the latest commercially available optical coherence tomography (OCT) mapping software, version 3.0, from the Stratus OCT (OCT3)...
  30. ncbi Age- and gender-specific reference values of estimated GFR in Caucasians: the Nijmegen Biomedical Study
    J F M Wetzels
    Department of Nephrology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Kidney Int 72:632-7. 2007
    ..As part of the overall study, we provide reference values of estimated glomerular filtration rate (GFR) for this Caucasian population without expressed risk...
  31. ncbi Serum inhibin B and follicle-stimulating hormone levels as tools in the evaluation of infertile men: significance of adequate reference values from proven fertile men
    Anna Maria Andersson
    Department of Growth and Reproduction, Copenhagen University Hospital, DK 2100 Copenhagen, Denmark
    J Clin Endocrinol Metab 89:2873-9. 2004
    ....
  32. ncbi Reference values of handgrip dynamometry of healthy adults: a population-based study
    Michael Maia Schlüssel
    Programa de Pós Graduação em Nutrição, Instituto de Nutrição, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Clin Nutr 27:601-7. 2008
    ..This paper presents reference values for handgrip strength of healthy adults (age > or = 20 years) from a household survey.
  33. ncbi Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography-tandem mass spectrometry as a reference
    Heinz Jürgen Roth
    Limbach Laboratory, Department of Endocrinology and Oncology, Im Breitspiel 15, 69126 Heidelberg, Germany
    Ann Clin Biochem 45:153-9. 2008
    ..High variability in 25(OH)D measurements due to utilized test and assay technologies and the lack of standardization against reference materials and reference method often confounds proper assessment of vitamin D status...
  34. ncbi Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies
    T Tuomi
    Department of Endocrinology, Lund University, Sweden
    Diabetes 48:150-7. 1999
    ..Further, we propose that LADA be defined as GADab positivity (>5 relative units) in patients older than 35 years at onset of type 2 diabetes...
  35. ncbi Reference values for peripheral blood lymphocyte phenotypes applicable to the healthy adult population in Switzerland
    Leslie R Bisset
    Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Eur J Haematol 72:203-12. 2004
    Use of domestic reference values is known to improve the accuracy of flow cytometric analysis by integrating local variation due to race, gender, and age...
  36. ncbi Body mass index of 0 to 45-y-old Danes: reference values and comparison with published European reference values
    K Nysom
    Section of Paediatric Haematology and Oncology, The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark
    Int J Obes Relat Metab Disord 25:177-84. 2001
    To generate body mass index (weight/height(2) (kg/m(2)), BMI) reference values for 0 to 45-y-old Danes and compare these with published European reference values.
  37. ncbi Acupuncture modulates the limbic system and subcortical gray structures of the human brain: evidence from fMRI studies in normal subjects
    K K Hui
    MGH NMR Center, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston 02129, USA
    Hum Brain Mapp 9:13-25. 2000
    ..We hypothesize that modulation of subcortical structures may be an important mechanism by which acupuncture exerts its complex multisystem effects...
  38. pmc Reference ranges for spirometry across all ages: a new approach
    Sanja Stanojevic
    Portex Respiratory Physiology Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH UK
    Am J Respir Crit Care Med 177:253-60. 2008
    ....
  39. ncbi Forced spirometry reference values for Norwegian adults: the Bronchial Obstruction in Nord-Trøndelag Study
    A Langhammer
    , The Norwegian University of Science and Technology (NTNU, Verdal
    Eur Respir J 18:770-9. 2001
    ..After a plateau in younger adults, the variables declined by age. The reference values for forced expiratory volume in one second and forced vital capacity from the present study, were higher than ..
  40. ncbi Independent component analysis of fMRI group studies by self-organizing clustering
    Fabrizio Esposito
    Second Division of Neurology, Second University of Naples, Italy
    Neuroimage 25:193-205. 2005
    ..This property is particularly of interest for a blind group and subgroup pattern extraction and selection...
  41. pmc Reference values for serum creatinine in children younger than 1 year of age
    Dirk P Boer
    Department of Paediatric Nephrology, Erasmus MC Sophia Children s Hospital, Erasmus University Medical Center, Dr Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands
    Pediatr Nephrol 25:2107-13. 2010
    Reliable reference values of enzymatically assayed serum creatinine categorized in small age intervals are lacking in young children...
  42. ncbi Nomogram for the decline in serum antimüllerian hormone: a population study of 9,601 infertility patients
    Scott M Nelson
    Reproductive and Maternal Medicine, Faculty of Medicine, University of Glasgow, Glasgow, Scotland
    Fertil Steril 95:736-41.e1-3. 2011
    ..To define an optimal model for the decline in circulating antimüllerian hormone (AMH) with age and develop a validated age-related nomogram...
  43. ncbi Reference values of maximum isometric muscle force obtained in 270 children aged 4-16 years by hand-held dynamometry
    E A Beenakker
    Department of Neurology, University Hospital Groningen, Hanzeplein 1, 9700 RB, The, Groningen, Netherlands
    Neuromuscul Disord 11:441-6. 2001
    ..The purpose of this study was to establish reference values for muscle force in children aged 4-16 years, obtained by hand-held dynamometry in 11 muscle groups...
  44. ncbi Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance
    Ahmad R Hariri
    Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland 20892 1384, USA
    J Neurosci 23:6690-4. 2003
    ..These data implicate a specific genetic mechanism for substantial normal variation in human declarative memory and suggest that the basic effects of BDNF signaling on hippocampal function in experimental animals are important in humans...
  45. ncbi Distribution of 24-h ambulatory blood pressure in children: normalized reference values and role of body dimensions
    Elke Wühl
    Division of Pediatric Nephrology, University Children s Hospital, Heidelberg, Germany
    J Hypertens 20:1995-2007. 2002
    ..The statistical use of pediatric ABPM reference values has been compromised by the non-Gaussian distribution of 24-h blood pressure (BP) in children.
  46. ncbi Quantile regression methods for reference growth charts
    Ying Wei
    Department of Biostatistics, Columbia University, New York, NY, USA
    Stat Med 25:1369-82. 2006
    ..Quantile specific autoregressive models for unequally spaced measurements are introduced and their application to diagnostic screening is illustrated...
  47. pmc SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease
    Jeffrey B Schwimmer
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics University of California, San Diego School of Medicine, San Diego, California 92103 8450, USA
    Gastroenterology 138:1357-64, 1364.e1-2. 2010
    ..The appropriate alanine aminotransferase (ALT) threshold value to use for diagnosis of chronic liver disease in children is unknown. We sought to develop gender-specific, biology-based, pediatric ALT thresholds...
  48. ncbi Isometric muscle torque in children 5 to 15 years of age: normative data
    Meta Nyström Eek
    Department of Paediatrics, Queen Silvia Children s Hospital, Goteborg University, Sweden
    Arch Phys Med Rehabil 87:1091-9. 2006
    To establish reference values of arm and leg muscle strength as measured by isometric torque production in healthy children.
  49. pmc Protein p16 as a marker of dysplastic and neoplastic alterations in cervical epithelial cells
    Galina Volgareva
    Institute of Carcinogenesis, N N Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow 115478, Russia
    BMC Cancer 4:58. 2004
    ....
  50. ncbi Reference values for lung function: past, present and future
    S Stanojevic
    Portex Respiratory Physiology Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
    Eur Respir J 36:12-9. 2010
    ..We aim to highlight some of the main issues in selecting and using reference equations and discuss how recent developments may improve interpretation of pulmonary function results...
  51. ncbi The IFCC recommendation on estimation of reference intervals. The RefVal program
    Helge Erik Solberg
    Department of Clinical Chemistry, Rikshospitalet, Oslo, Norway
    Clin Chem Lab Med 42:710-4. 2004
    ..Federation of Clinical Chemistry (IFCC) published between 1987--91 a series of six recommendations on reference values in laboratory medicine. This paper reviews the history and scope of the fifth part of these recommendations...
  52. ncbi Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses
    Kevan L Hartshorn
    Department of Medicine, Section of Hematology Oncology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Physiol Lung Cell Mol Physiol 285:L1066-76. 2003
    ..Furthermore, removal of gp-340 from BAL fluid and saliva significantly reduced anti-IAV activity. Hence, gp-340 contributes to defense against IAV and may be particularly relevant to defense against SP-D-resistant viral strains...
  53. ncbi Monitoring low benzene exposure: comparative evaluation of urinary biomarkers, influence of cigarette smoking, and genetic polymorphisms
    Silvia Fustinoni
    Department of Occupational and Environmental Health, University of Milan, Italy
    Cancer Epidemiol Biomarkers Prev 14:2237-44. 2005
    ..15 ppm), smoking may be regarded as the major source of benzene intake; among the study indices, U-benzene is the marker of choice for biomonitoring low-level occupational and environmental benzene exposure...
  54. ncbi Reference values for a multiple repetition 6-minute walk test in healthy adults older than 20 years
    W J Gibbons
    Respiratory Division, Department of Medicine, Montreal Chest Institute, Royal Victoria Hospital, Montreal, Quebec, Canada
    J Cardiopulm Rehabil 21:87-93. 2001
    ..6MWD) from among several repetitions (best 6MWD) in a wide age range of healthy volunteers to develop reference values for the multiple repetition 6MWD, and (2) investigate the influence of demographics, anthropometrics, and ..
  55. ncbi The importance of swing-phase initial conditions in stiff-knee gait
    Saryn R Goldberg
    Mechanical Engineering Department, Biomechanical Engineering Division, Stanford University, Stanford, CA 94305 3030, USA
    J Biomech 36:1111-6. 2003
    ..These results suggest that the diminished knee flexion of many persons with stiff-knee gait may be caused by abnormally low knee flexion velocity at toe-off as opposed to excessive knee extension moments during swing...
  56. pmc Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR
    Ann Britt Nygard
    University of Copenhagen, Faculty of Life Sciences, Department of Basic Animal and Veterinary Sciences, Division of Genetics and Bioinformatics, Groennegaardsvej 3, 1870 Frederiksberg C, Denmark
    BMC Mol Biol 8:67. 2007
    ..Selection of high quality reference genes is of crucial importance for the interpretation of data generated by real-time qPCR...
  57. ncbi Evaluation of BMI-based classification of adolescent overweight and obesity: choice of percentage body fat cutoffs exerts a large influence. The COMPASS study
    M Neovius
    Department of Public Health Sciences, Karolinska Institutet, Karolinska University Hospital Norrbacka, Stockholm, Sweden
    Eur J Clin Nutr 62:1201-7. 2008
    ..To determine the impact of commonly used body fat percentage (%BF) references when evaluating the sensitivity, specificity and misclassifications of body mass index (BMI) for obesity screening in adolescence...
  58. ncbi Body fat percentile curves for U.S. children and adolescents
    Kelly R Laurson
    School of Kinesiology and Recreation, Illinois State University, Normal, Illinois 61790, USA
    Am J Prev Med 41:S87-92. 2011
    ..To date, several studies have been published outlining reference percentiles for BMI in children and adolescents. In contrast, there are limited reference data on percent body fat (%BF) in U.S. youth...
  59. ncbi 1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders
    Lidia Gabis
    Weinberg Child Development Center, Safra Children s Hospital, Tel Hashomer, Israel
    J Child Neurol 23:766-74. 2008
    ..Magnetic resonance spectroscopy can provide important information regarding abnormal brain metabolism and clinical classification in autism spectrum disorders...
  60. pmc An MRI and proton spectroscopy study of the thalamus in children with autism
    Antonio Y Hardan
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
    Psychiatry Res 163:97-105. 2008
    ..Further investigations of this structure are warranted, since it plays an important role in information processing as part of the cortico-thalamo-cortical pathways...
  61. ncbi Echocardiographic evaluation of ventricular function in mice
    Jeffrey N Rottman
    Division of Cardiovascular Medicine, Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 6300, USA
    Echocardiography 24:83-9. 2007
    ..Finally, echocardiography exists among several competing imaging technologies, and these alternatives are compared...
  62. ncbi Magnetic resonance tissue phase mapping of myocardial motion: new insight in age and gender
    Daniela Föll
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstrasse 55, Freiburg, Germany
    Circ Cardiovasc Imaging 3:54-64. 2010
    ..Magnetic resonance phase-contrast imaging (tissue phase mapping) enabling the analysis of segmental, 3-directional myocardial velocities with high temporal resolution (13.8 ms) was used to assess left ventricular motion...
  63. pmc The definition of insulin resistance using HOMA-IR for Americans of Mexican descent using machine learning
    Hui Qi Qu
    Division of Epidemiology, Human Genetics and Environmental Sciences, Brownsville Regional Campus, The University of Texas School of Public Health, Brownsville, Texas, United States of America
    PLoS ONE 6:e21041. 2011
    ..This study defines the reference range of HOMA-IR index in an adult Hispanic population based with machine learning methods...
  64. ncbi Activation of the amygdala and anterior cingulate during nonconscious processing of sad versus happy faces
    William D S Killgore
    Cognitive Neuroimaging Laboratory, McLean Hospital Harvard Medical School, Belmont, MA 02478, USA
    Neuroimage 21:1215-23. 2004
    ..Findings suggest that the amygdala and anterior cingulate are important components of a network involved in detecting and discriminating affective information presented below the normal threshold of conscious visual perception...
  65. ncbi Enhancement of non-dominant hand motor function by anodal transcranial direct current stimulation
    Paulo S Boggio
    Department of Experimental Psychology, University of Sao Paulo, Brazil
    Neurosci Lett 404:232-6. 2006
    ..We speculate that the under-use of the non-dominant hand with its associated consequences in cortical plasticity might be one of the reasons to explain motor performance enhancement in the non-dominant hand only...
  66. ncbi Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence
    Shumei Sun Guo
    Department of Community Health, Wright State University, Dayton, OH 45420, USA
    Am J Clin Nutr 76:653-8. 2002
    ..The Centers for Disease Control and Prevention (CDC) introduced the clinical use of the body mass index (BMI; in kg/m(2)) in growth charts for young males and females...
  67. ncbi Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES III)
    Elizabeth Selvin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Diabetes Care 30:234-8. 2007
    ..The objective of this study is to test the hypothesis that low normal levels of total, free, and bioavailable testosterone are associated with prevalent diabetes in men...
  68. ncbi Reference values for right ventricular volumes and ejection fraction with real-time three-dimensional echocardiography: evaluation in a large series of normal subjects
    Gloria Tamborini
    Centro Cardiologico Monzino, IRCCS, Department of Cardiovascular Sciences, University of Milan, Milan, Italy
    J Am Soc Echocardiogr 23:109-15. 2010
    ..The aim of this study was to provide normal reference values for RV volumes and function using this technique.
  69. ncbi The electrophysiological dynamics of interference during the Stroop task
    Simon Hanslmayr
    Department of Experimental Psychology, Regensburg University, Regensburg, Germany
    J Cogn Neurosci 20:215-25. 2008
    ..Thereafter, sustained phase coupling between the ACC and the prefrontal cortex occurs, which most likely reflects the engagement of cognitive control mechanisms...
  70. ncbi Population reference values for plasma total homocysteine concentrations in US adults after the fortification of cereals with folic acid
    Vijay Ganji
    Department of Human Nutrition, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA
    Am J Clin Nutr 84:989-94. 2006
    ..Folate intake is inversely associated with circulating total homocysteine (tHcy). Elevated tHcy is directly associated with cardiovascular disease risk...
  71. ncbi References for growth and pubertal development from birth to 21 years in Flanders, Belgium
    M Roelants
    Laboratory of Anthropogenetics, Vrije Universiteit Brussel VUB, Belgium
    Ann Hum Biol 36:680-94. 2009
    ..Reference charts that were until recently used in Belgium are based on samples collected more than 30 years ago, and references for body mass index (BMI) and pubertal development have not been established before...
  72. ncbi Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Am Geriatr Soc 53:1675-80. 2005
    ..To define clinically relevant cutpoints for usual gait speed and to investigate their predictive value for health-related events in older persons...
  73. ncbi Body mass index percentiles for children and adolescents in Germany based on a nationally representative sample (KiGGS 2003-2006)
    A Schaffrath Rosario
    Robert Koch Institute, Department of Epidemiology and Health Reporting, Berlin, Germany
    Eur J Clin Nutr 64:341-9. 2010
    ....
  74. ncbi Reference values for hair cotinine as a biomarker of active and passive smoking in women of reproductive age, pregnant women, children, and neonates: systematic review and meta-analysis
    Ana Florescu
    Public Health Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Ther Drug Monit 29:437-46. 2007
    ..These new values should facilitate clinical diagnosis of active and passive exposure to tobacco smoke. Such diagnosis is critical in pregnancy and in a large number of tobacco-induced medical conditions...
  75. ncbi Development of a multiplex MethyLight assay for the detection of multigene methylation in human colorectal cancer
    Qiong He
    Department of Human Anatomy and Neurobiology, Sun Yat Sen University, Guangzhou, Guangdong, P R China
    Cancer Genet Cytogenet 202:1-10. 2010
    ....
  76. pmc Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology
    R E Banks
    ICRF Cancer Medicine Research Unit, St James s University Hospital, Leeds UK
    Br J Cancer 77:956-64. 1998
    ..e.g. wound healing, and in tumour metastasis, when platelets adhering to circulating tumour cells may release VEGF at points of adhesion to endothelium, leading to hyperpermeability and extravasation of cells...
  77. pmc The ratio of FEV1 to FVC as a basis for establishing chronic obstructive pulmonary disease
    Carlos A Vaz Fragoso
    Yale Claude D Pepper Older Americans Independence Center, New Haven, Connecticut, USA
    Am J Respir Crit Care Med 181:446-51. 2010
    ..The clinical validity of this threshold as a basis for establishing chronic obstructive pulmonary disease is unknown...
  78. ncbi Shallow medial tibial plateau and steep medial and lateral tibial slopes: new risk factors for anterior cruciate ligament injuries
    Javad Hashemi
    Department of Mechanical Engineering, Texas Tech University, 7th and Boston Streets, Lubbock, TX 79409 1021, USA
    Am J Sports Med 38:54-62. 2010
    ....
  79. ncbi Keep it simple: a case for using classical minimum norm estimation in the analysis of EEG and MEG data
    Olaf Hauk
    Cognition and Brain Sciences Unit, Medical Research Council, Cambridge, UK
    Neuroimage 21:1612-21. 2004
    ..g., single-trial data) are analyzed. For that purpose, an efficient and practical implementation of this method will be suggested and illustrated with simulations using a realistic head geometry...
  80. ncbi Stunting, adiposity, and low-grade inflammation in African adolescents from a township high school
    Herculina Salome Kruger
    School of Physiology, Nutrition and Consumer Science, North West University, Potchefstroom, South Africa
    Nutrition 26:90-9. 2010
    ..The objective of this study was to compare the inflammatory status of children with differences in nutritional status...
  81. ncbi Reduction of rise in blood pressure and cortisol release during stress by Ginkgo biloba extract (EGb 761) in healthy volunteers
    D Jezova
    Laboratory of Pharmacological Neuroendocrinology, Slovak Academy of Sciences, Bratislava
    J Physiol Pharmacol 53:337-48. 2002
    ..Thus, this study provides evidence that EGb 761 has an inhibitory action on blood pressure and it may influence cortisol release in response to some stress stimuli...
  82. ncbi Measurement of cerebrospinal fluid flow at the cerebral aqueduct by use of phase-contrast magnetic resonance imaging: technique validation and utility in diagnosing idiopathic normal pressure hydrocephalus
    Patrick H Luetmer
    Department of Diagnostic Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Neurosurgery 50:534-43; discussion 543-4. 2002
    ....
  83. pmc Biomarkers of ovarian function in girls and women with classic galactosemia
    Rebecca D Sanders
    Graduate Program in Biochemistry, Cell, and Developmental Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Fertil Steril 92:344-51. 2009
    ..To determine whether premature ovarian insufficiency (POI) associated with classic galactosemia results from a true impairment of ovarian function or from aberrant FSH...
  84. ncbi fMRI resting state networks define distinct modes of long-distance interactions in the human brain
    M De Luca
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, UK
    Neuroimage 29:1359-67. 2006
    ..Because RSNs reflect interactions in cognitively relevant functional networks, they offer a new approach to the characterization of state changes with pathology and the effects of drugs...
  85. ncbi Positive interpretation training: effects of mental imagery versus verbal training on positive mood
    Emily A Holmes
    MRC Cognition and Brain Sciences Unit, Cambridge, UK
    Behav Ther 37:237-47. 2006
    ..This study also provides the first test of a standardized intervention using an "interpretive bias training" paradigm to improve positive mood...
  86. pmc Adaptive changes in early and late blind: a FMRI study of verb generation to heard nouns
    H Burton
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurophysiol 88:3359-71. 2002
    ..It remains possible that these responses represent adaptations which initially are for processing either sound or touch, but which are later generalized to the other modality during acquisition of Braille reading skills...
  87. ncbi Varying femoral tunnels between the anatomical footprint and isometric positions: effect on kinematics of the anterior cruciate ligament-reconstructed knee
    Volker Musahl
    Department of Orthopaedic Surgery, University of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Am J Sports Med 33:712-8. 2005
    ..Knee kinematics and in situ forces resulting from anterior cruciate ligament reconstructions with 2 femoral tunnel positions were evaluated...
  88. ncbi First reference curves of waist circumference for German children in comparison to international values: the PEP Family Heart Study
    Peter Schwandt
    Arteriosklerose Präventions Institut, Munich Nuremberg, Germany
    World J Pediatr 4:259-66. 2008
    ..Considering the lack of reference values in Germany, we developed age- and gender-specific WC smoothed reference curves in German children, and ..
  89. ncbi Classification of the myoelectric signal using time-frequency based representations
    K Englehart
    Institute of Biomedical Engineering, University of New Brunswick, Fredericton, Canada
    Med Eng Phys 21:431-8. 1999
    ....
  90. pmc A detailed examination of cytokine abnormalities in Major Depressive Disorder
    N M Simon
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Eur Neuropsychopharmacol 18:230-3. 2008
    ..These data support a generalized chronic inflammatory state in MDD, and implicate additional cytokines and chemokines previously linked to cardiovascular disease...
  91. ncbi Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease
    Andrew D Rule
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Ann Intern Med 141:929-37. 2004
    ..However, healthy persons were not included in the development of the MDRD equation...
  92. ncbi Lung function testing in the elderly--can we still use FEV1/FVC<70% as a criterion of COPD?
    Astri Medbø
    Institute of Community Medicine, University of Tromsø, 9038 Tromsø, Norway
    Respir Med 101:1097-105. 2007
    ..COPD is known as a disease which is frequently under-diagnosed. However, there is a risk of over diagnosis when this diagnostic threshold is applied among the elderly...
  93. ncbi T2 relaxation time of cartilage at MR imaging: comparison with severity of knee osteoarthritis
    Timothy C Dunn
    Department of Radiology, University of California at San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107 1739, USA
    Radiology 232:592-8. 2004
    ....
  94. ncbi Intranasal insulin reduces body fat in men but not in women
    Manfred Hallschmid
    Institute of Neuroendocrinology, University of Lubeck, Ratzeburger Allee 160, Haus 23a, 23538 Lubeck, Germany
    Diabetes 53:3024-9. 2004
    ..Our results provide a strong, first confirmation in humans that insulin acts as a negative feedback signal in the regulation of adiposity and point to a differential sensitivity to the catabolic effects of insulin based on sex...
  95. ncbi National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes
    David A Morrow
    Clin Chem 53:552-74. 2007
  96. ncbi Estimation of bone mineral density by digital X-ray radiogrammetry: theoretical background and clinical testing
    A Rosholm
    Pronosco A S, Vedbaek, Hvidovre Hospital, University of Copenhagen, Denmark
    Osteoporos Int 12:961-9. 2001
    ..It is concluded that the DXR method offers a BMD estimate with a good correlation with distal forearm BMD, a low variation between geographical sites and a precision that potentially allows for relatively short observation intervals...
  97. pmc Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study
    Clara Kelliny
    Medical Research Council Epidemiology Unit, Addenbrooke s Hospital, Institute of Metabolic Science, Cambridge, U K
    Diabetes 58:2939-45. 2009
    ..The goal of this study was to investigate whether the effects of common genetic variants associated with fasting glucose in adults are detectable in healthy children...
  98. ncbi Analysis of dose-response curves to methacholine. An approach suitable for population studies
    G O'CONNOR
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115
    Am Rev Respir Dis 136:1412-7. 1987
    ..Dose-response slope is proposed as a quantitative measure of nonspecific airway responsiveness that avoids censoring and that may be particularly useful in epidemiologic studies...
  99. ncbi Quantitative MRI of the temporal lobe, amygdala, and hippocampus in normal human development: ages 4-18 years
    J N Giedd
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892 1600, USA
    J Comp Neurol 366:223-30. 1996
    ....
  100. ncbi Sex and race differences in fat distribution among Asian, African-American, and Caucasian prepubertal children
    Qing He
    Obesity Research Center, St Luke s Roosevelt Hospital, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    J Clin Endocrinol Metab 87:2164-70. 2002
    ..This comparison of African-American, Asian, and Caucasian prepubertal children suggests phenotypic differences. Additional studies are needed to explore the metabolic and health risk implications of these findings...
  101. ncbi Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: implications for systolic and diastolic reserve limitations
    Miho Kawaguchi
    Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Circulation 107:714-20. 2003
    ..We hypothesized that such patients also display combined ventricular-systolic and arterial stiffening that can exacerbate blood pressure lability and diastolic dysfunction under stress...

Research Grants22

  1. Cholesterol Homeostasis in Framingham Offspring Study
    Alice Lichtenstein; Fiscal Year: 2006
    ..define the relationship between markers of cholesterol absorption and synthesis, and CVD outcomes; establish reference values for measures of cholesterol absorption and synthesis; and assess the predictive value of these measures to ..
  2. SEQUENTIAL ANALYSIS OF HEMATOLOGIC MEASUREMENTS
    Christine McLaren; Fiscal Year: 1992
    ..statistical methods for the sequential analysis of hematologic measurements to provide patient-specific reference values that will facilitate the detection and diagnosis of anemia...
  3. Noninvasive Quantification of the Resistance Baroeflex
    Ramakrishna Mukkamala; Fiscal Year: 2006
    ..gain values determined by applying the algorithm to ABP and CO measured during AV sequential pacing with reference values established by applying MRA to ABP, CVP, and CO measured during a set of adjustments to ventricular rate and ..
  4. Novel Technologies to Identify Preclinical Coronary Disease in High Risk Families
    Lewis C Becker; Fiscal Year: 2010
    ..Data will be used to general reference values for plaque volumes and to determine the value of MDCTA as a method to track responsiveness to therapy in a ..
  5. QUANTITATIVE METALLOPROTEOMICS: THE HUMAN ERYTHROCYTE
    Bruce Ames; Fiscal Year: 2006
    ..for every class of cellular macromolecule Assessing RBC metal content is a standard clinical test, yet reference values for many of the trace metals and metalloids in the RBC are surprisingly not well known...
  6. Bone-Specific Assessment of Marrow Cellularity by H-NMR Spectroscopy
    JOSE CARLOS PICHARDO; Fiscal Year: 2010
    ..However, the model is partially based on the use of standardized reference values bone marrow cellularity data from the radiation protection literature, data that was compiled from various ..
  7. PATTERN OF FATTY ACIDS IN FRAMINGHAM OFFSPRING
    Edward Siguel; Fiscal Year: 1991
    ..Tables of reference values will be produced for the general population and for selected subpopulations...
  8. Vulnerability to Smallpox Due to Declining CTL Immunity
    Innocent Mbawuike; Fiscal Year: 2003
    ..Data from recent vaccinees might also serve as reference values for new smallpox vaccines that might be developed since specific correlates of immunity against smallpox (..
  9. Hair and toenail nicotine as biomarkers of actual population exposure to tobacco
    Wael K Al Delaimy; Fiscal Year: 2010
    ..Some of the obstacles to wider use of biomarkers are the lack of population based reference values for determination of standards of exposure or cut-off points in relation to health outcomes...
  10. LIPOPROTEIN (A) STANDARDIZATION PROGRAM
    Santica Marcovina; Fiscal Year: 2000
    ..Often there is no reference to population-based reference values. Additionally, none of the existing assays have been evaluated to establish what exactly is being measured, i...
  11. Aging and Alcohol Demand
    Henry Saffer; Fiscal Year: 2005
    ..The PSID although it is a general population survey is important since it can provide reference values for the effects of risk preference on alcohol consumption. There are no other studies of this question...
  12. ACOUSTICAL POWER FLOW AS AN AUDIOLOGICAL TOOL
    PATRICIA JENG; Fiscal Year: 2001
    ..The accuracy of the PFA is expected to be within 2 dB of the reference values obtained by Voss and Allen (J. Acoust. Am. 95 372-384, 1994)...
  13. Raman spectroscopy of bacteria in oral plaques
    ANDREW BERGER; Fiscal Year: 2006
    ..The target of each experiment will be Raman-based prediction of bacterial concentrations, compared to reference values. Accuracy of prediction will be characterized in each step, providing benchmarks for subsequent studies on ..
  14. Bone-Sparing by Ca Salts With & Without Extra Phosphorus
    Robert Heaney; Fiscal Year: 2008
    ..1 Description, ..
  15. Effects of Aging on Executive Processes
    Timothy Salthouse; Fiscal Year: 2006
    ..e., specific to individual variables or common to many variables) at which age-related influences operate on executive process variables. ..
  16. Quantification of Host Markers in GCF Using CBIB
    Ricardo Teles; Fiscal Year: 2007
    ..Moreover, this methodology is at the forefront of new approaches in proteomics, and carries enormous promise for translational applications in the near future. [unreadable] [unreadable]..
  17. Emotional Mechanisms /Blood-Injection-Injury Phobia
    Olubunmi Olatunji; Fiscal Year: 2004
    ..This research will provide an important contribution to the understanding of the emotions that mediate BII phobia, thus potentially providing a foundation for incorporating effective treatment strategies. ..
  18. Genome-wide association of common alleles with long-term diabetic complications
    Andrew Paterson; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  19. Mechanisms of Vitamin E Function Studied in Zebrafish
    Maret G Traber; Fiscal Year: 2010
    ..the molecular targets altered by - tocopherol-deficiency in the zebrafish will provide a solid basis for understanding why humans require -tocopherol for reproduction as well as to maintain a healthy nervous system ..
  20. Exploring Growth Energy Expenditure in Normal-Weight and Overweight Children
    ZiMian Wang; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  21. Investigation of a Behavioral Substitute for Sunbathing
    Sherry Pagoto; Fiscal Year: 2007
    ..Prevention interventions that target high-risk segments of the community in settings where risk behavior occurs have potential for a large and focused public health impact. [unreadable] [unreadable] [unreadable]..
  22. Massaging Preterm Infants Enhances Growth
    Tiffany Field; Fiscal Year: 2006
    ..abstract_text> ..