periodicity

Summary

Summary: The tendency of a phenomenon to recur at regular intervals; in biological systems, the recurrence of certain activities (including hormonal, cellular, neural) may be annual, seasonal, monthly, daily, or more frequently (ultradian).

Top Publications

  1. pmc Determinants of relapse periodicity in Plasmodium vivax malaria
    Nicholas J White
    Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
    Malar J 10:297. 2011
  2. ncbi Entrainment of neuronal oscillations as a mechanism of attentional selection
    Peter Lakatos
    Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute, Orangeburg, NY 10962, USA
    Science 320:110-3. 2008
  3. ncbi A segmentation clock with two-segment periodicity in insects
    Andres F Sarrazin
    Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Nikolaou Plastira 100, GR 70013 Heraklio, Crete, Greece
    Science 336:338-41. 2012
  4. pmc Reduction of theta rhythm dissociates grid cell spatial periodicity from directional tuning
    Mark P Brandon
    Center for Memory and Brain, Department of Psychology, Graduate Program for Neuroscience, Boston University, 2 Cummington Street, Boston, MA 02215, USA
    Science 332:595-9. 2011
  5. pmc Circuits controlling vertebrate locomotion: moving in a new direction
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Rev Neurosci 10:507-18. 2009
  6. ncbi Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks
    Marlene Bartos
    Physiologisches Institut der Universität Freiburg, Abteilung 1, Hermann Herder Strasse 7, D 79104 Freiburg, Germany
    Nat Rev Neurosci 8:45-56. 2007
  7. ncbi The spatial periodicity of grid cells is not sustained during reduced theta oscillations
    Julie Koenig
    Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego, USA
    Science 332:592-5. 2011
  8. ncbi Locomotor circuits in the mammalian spinal cord
    Ole Kiehn
    Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S17177, Sweden
    Annu Rev Neurosci 29:279-306. 2006
  9. ncbi Sensorimotor synchronization: a review of the tapping literature
    Bruno H Repp
    Haskins Laboratories, New Haven, CT 06511 6624, USA
    Psychon Bull Rev 12:969-92. 2005
  10. pmc Dengue dynamics in Binh Thuan province, southern Vietnam: periodicity, synchronicity and climate variability
    Khoa T D Thai
    Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, Amsterdam, The Netherlands
    PLoS Negl Trop Dis 4:e747. 2010

Detail Information

Publications361 found, 100 shown here

  1. pmc Determinants of relapse periodicity in Plasmodium vivax malaria
    Nicholas J White
    Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
    Malar J 10:297. 2011
    ..The intervals between relapses display a remarkable periodicity which has not been explained...
  2. ncbi Entrainment of neuronal oscillations as a mechanism of attentional selection
    Peter Lakatos
    Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute, Orangeburg, NY 10962, USA
    Science 320:110-3. 2008
    ..These instrumental functions of low-frequency oscillations support a conceptual framework that integrates numerous earlier findings...
  3. ncbi A segmentation clock with two-segment periodicity in insects
    Andres F Sarrazin
    Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Nikolaou Plastira 100, GR 70013 Heraklio, Crete, Greece
    Science 336:338-41. 2012
    ..We find that the segmentation gene odd-skipped (Tc-odd) oscillates with a two-segment periodicity in the beetle Tribolium castaneum...
  4. pmc Reduction of theta rhythm dissociates grid cell spatial periodicity from directional tuning
    Mark P Brandon
    Center for Memory and Brain, Department of Psychology, Graduate Program for Neuroscience, Boston University, 2 Cummington Street, Boston, MA 02215, USA
    Science 332:595-9. 2011
    ..During MS inactivation, grid cells lost their spatial periodicity, whereas head-direction cells maintained their selectivity...
  5. pmc Circuits controlling vertebrate locomotion: moving in a new direction
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Rev Neurosci 10:507-18. 2009
    ....
  6. ncbi Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks
    Marlene Bartos
    Physiologisches Institut der Universität Freiburg, Abteilung 1, Hermann Herder Strasse 7, D 79104 Freiburg, Germany
    Nat Rev Neurosci 8:45-56. 2007
    ..Computational analysis further suggests that synaptic specialization turns interneuron networks into robust gamma frequency oscillators...
  7. ncbi The spatial periodicity of grid cells is not sustained during reduced theta oscillations
    Julie Koenig
    Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego, USA
    Science 332:592-5. 2011
    ..Precisely timed neural activity within single cells or local networks is thus required for periodic spatial firing but not for single place fields...
  8. ncbi Locomotor circuits in the mammalian spinal cord
    Ole Kiehn
    Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S17177, Sweden
    Annu Rev Neurosci 29:279-306. 2006
    ..Molecular and genetic approaches that have the potential to elucidate the function of populations of CPG interneurons are also discussed...
  9. ncbi Sensorimotor synchronization: a review of the tapping literature
    Bruno H Repp
    Haskins Laboratories, New Haven, CT 06511 6624, USA
    Psychon Bull Rev 12:969-92. 2005
    ..They exemplify the general distinction between subconscious mechanisms of action regulation and conscious processes involved in perceptual judgment and action planning...
  10. pmc Dengue dynamics in Binh Thuan province, southern Vietnam: periodicity, synchronicity and climate variability
    Khoa T D Thai
    Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, Amsterdam, The Netherlands
    PLoS Negl Trop Dis 4:e747. 2010
    ..The epidemiology is complex with long inter-epidemic intervals and endemic with seasonal fluctuations. This study was initiated to investigate dengue transmission dynamics in Binh Thuan province, southern Vietnam...
  11. ncbi Rhythm and beat perception in motor areas of the brain
    Jessica A Grahn
    MRC Cognition and Brain Sciences Unit, Cambridge, UK
    J Cogn Neurosci 19:893-906. 2007
    ..We conclude that, in addition to their role in movement production, the basal ganglia and SMAs may mediate beat perception...
  12. pmc Encoding of oscillations by axonal bursts in inferior olive neurons
    Alexandre Mathy
    Wolfson Institute for Biomedical Research, Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK
    Neuron 62:388-99. 2009
    ..Our results challenge the view that the climbing fiber conveys an all-or-none signal to the cerebellar cortex and help to link learning and timing theories of olivocerebellar function...
  13. ncbi Temporal aspects of stimulus-driven attending in dynamic arrays
    Mari Riess Jones
    Psychology Department, The Ohio State University, USA
    Psychol Sci 13:313-9. 2002
    ..This effect persisted over time, but disappeared when the rhythm of interpolated tones was either missing or irregular...
  14. pmc Nonstationary influence of El Niño on the synchronous dengue epidemics in Thailand
    Bernard Cazelles
    CNRS UMR 7625, Ecole Normale Superieure, Paris, France
    PLoS Med 2:e106. 2005
    ..Here we address the role of climate variability in shaping the interannual pattern of dengue epidemics...
  15. pmc JTK_CYCLE: an efficient nonparametric algorithm for detecting rhythmic components in genome-scale data sets
    Michael E Hughes
    Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA
    J Biol Rhythms 25:372-80. 2010
    ..These data suggest that JTK_CYCLE is an ideal tool for identifying and characterizing oscillations in genome-scale data sets...
  16. ncbi Role of gap junctions in synchronized neuronal oscillations in the inferior olive
    Elena Leznik
    Department of Physiology and Neuroscience, New York University Medical School, NY 10016, USA
    J Neurophysiol 94:2447-56. 2005
    ..The findings support the view that oscillatory properties of single IO neurons endow the system with important reset dynamics, while gap junctions are mainly required for synchronized neuronal ensemble activity...
  17. ncbi Asymmetric transfer of visuomotor learning between discrete and rhythmic movements
    Tsuyoshi Ikegami
    Graduate School of Education, The University of Tokyo, Bunkyo ku, Tokyo 113 0033, Japan
    J Neurosci 30:4515-21. 2010
    ....
  18. pmc Dynamics of Active Sensing and perceptual selection
    Charles E Schroeder
    Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute for Psychiatric Research, USA
    Curr Opin Neurobiol 20:172-6. 2010
    ..These observations outline the essentials of an Active Sensing paradigm, and argue for increased emphasis on the study of sensory processes as specific to the dynamic motor/attentional context in which inputs are acquired...
  19. pmc Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis
    Yasutaka Niwa
    Institute for Virus Research, Kyoto University, Shogoin Kawahara, Sakyo ku, Kyoto, Japan
    Genes Dev 25:1115-20. 2011
    ..These results suggest that Notch oscillators define the prospective somite region, while Fgf oscillators regulate the pace of segmentation...
  20. ncbi Effects of correct and transformed visual feedback on rhythmic visuo-motor tracking: tracking performance and visual search behavior
    M Roerdink
    Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit, 1081BT Amsterdam, The Netherlands
    Hum Mov Sci 24:379-402. 2005
    ....
  21. ncbi Detecting periodic patterns in unevenly spaced gene expression time series using Lomb-Scargle periodograms
    Earl F Glynn
    Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA
    Bioinformatics 22:310-6. 2006
    ..The choice of statistic to evaluate the significance of the periodic patterns for unevenly spaced gene expression time series has not been well substantiated...
  22. ncbi Visual tracking and entrainment to an environmental rhythm
    R C Schmidt
    Department of Psychology, College of the Holy Cross, Worcester, MA 01610, USA
    J Exp Psychol Hum Percept Perform 33:860-70. 2007
    ..These findings highlight the importance of understanding the role of eye movements in environmental coordination...
  23. pmc Ready, set, reset: stimulus-locked periodicity in behavioral performance demonstrates the consequences of cross-sensory phase reset
    Ian C Fiebelkorn
    Cognitive Neurophysiology Laboratory, Children s Evaluation and Rehabilitation Center, Department of Pediatrics, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neurosci 31:9971-81. 2011
    ..present experiment uses a psychophysical approach in humans to demonstrate, for the first time, stimulus-locked periodicity in visual-target detection, following a temporally informative sound...
  24. ncbi Generation and propagation of subthreshold waves in a network of inferior olivary neurons
    Anna Devor
    Department of Neurobiology, Institute of Life Sciences, Hebrew University, Jerusalem 91904, Israel
    J Neurophysiol 87:3059-69. 2002
    ....
  25. pmc Ionic mechanisms of autorhythmic firing in rat cerebellar Golgi cells
    Lia Forti
    Dipartimento di Scienze Fisiologiche e Farmacologiche, Universita di Pavia, Via Forlanini 6, 27100 Pavia, Italy
    J Physiol 574:711-29. 2006
    ..The multiple ionic mechanisms shown here to contribute to GoC pacemaking should provide the substrate for fine regulation of firing frequency and precision, thus influencing the cyclic inhibition exerted by GoCs onto the cerebellar GL...
  26. ncbi Breeding periodicity for male sea turtles, operational sex ratios, and implications in the face of climate change
    Graeme C Hays
    Department of Pure and Applied Ecology, Institute of Environmental Sustainability, Swansea University, Singleton Park, Swansea SA2 8PP, UK
    Conserv Biol 24:1636-43. 2010
    ..seasons and identified individuals on their breeding grounds, using photoidentification, to determine breeding periodicity and operational sex ratios. Males returned to breed at least twice as frequently as females...
  27. ncbi Dynamic markers of altered gait rhythm in amyotrophic lateral sclerosis
    J M Hausdorff
    Margret and H A Rey Laboratory for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Appl Physiol (1985) 88:2045-53. 2000
    ..Moreover, a matrix of markers based on gait dynamics may be useful in characterizing certain pathologies of motor control and, possibly, in quantitatively monitoring disease progression and evaluating therapeutic interventions...
  28. ncbi A novel form of pigment-dispersing hormone in the central nervous system of the intertidal marine isopod, Eurydice pulchra (leach)
    David C Wilcockson
    Institute of Biological Environmental and Rural Sciences, Aberystwyth University, Penglais, Ceredigion, United Kingdom
    J Comp Neurol 519:562-75. 2011
    ..both tidal (activity) and circadian (chromatophore) rhythms, however, there was no evidence for a corresponding periodicity in the expression of pdh transcript, as determined by quantitative reverse transcriptase polymerase chain ..
  29. ncbi Glutamatergic input governs periodicity and synchronization of bursting activity in oxytocin neurons in hypothalamic organotypic cultures
    Jean Marc Israel
    INSERM U 378, I F R des Neurosciences, Universite Victor Segalen Bordeaux 2, 1 rue Camille Saint Saens, F 33077 Bordeaux, France
    Eur J Neurosci 17:2619-29. 2003
    ....
  30. ncbi Attention samples stimuli rhythmically
    Ayelet Nina Landau
    Ernst Strüngmann Institute for Neuroscience in Cooperation with Max Planck Society, Deutschordenstr 46, D 60528 Frankfurt, Germany
    Curr Biol 22:1000-4. 2012
    ..These findings show that selective attention samples multiple stimuli rhythmically, and they position spatial attention within the family of exploration behaviors...
  31. ncbi High-frequency network oscillations in cerebellar cortex
    Steven J Middleton
    Institute of Neuroscience, The Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK
    Neuron 58:763-74. 2008
    ..The ability of cerebellar cortex to generate population rhythms within the same frequency bands as neocortex suggests that they act as a common spatiotemporal code within which corticocerebellar dialog may occur...
  32. pmc Abnormal neural synchrony in schizophrenia
    Kevin M Spencer
    Department of Psychiatry, Harvard Medical School Veterans Affairs Boston Healthcare System, Brockton, Massachusetts 02301, USA
    J Neurosci 23:7407-11. 2003
    ..These findings support the hypothesis that schizophrenia is associated with impaired neural circuitry demonstrated as a failure of gamma band synchronization, especially in the 40 Hz range...
  33. pmc Using EEG to explore how rTMS produces its effects on behavior
    Jeffrey S Johnson
    Department of Psychiatry, University of Wisconsin Madison, 53719, USA
    Brain Topogr 22:281-93. 2010
    ..Simultaneous recording of the EEG thus offers an important means of directly testing assumptions about how rTMS exerts its effects on behavior...
  34. ncbi Unsupervised statistical learning underpins computational, behavioural, and neural manifestations of musical expectation
    Marcus T Pearce
    Department of Computing, Goldsmiths, University of London, London SE14 6NW, UK
    Neuroimage 50:302-13. 2010
    ....
  35. ncbi It don't mean a thing... Keeping the rhythm during polyrhythmic tension, activates language areas (BA47)
    P Vuust
    Center of Functionally Integrative Neuroscience, Aarhus University Hospital, Denmark
    Neuroimage 31:832-41. 2006
    ..We propose that BA47 is involved in general neuronal processing of temporal coherence subserving both language and music...
  36. ncbi Rhythmic episodes of subthreshold membrane potential oscillations in the rat inferior olive nuclei in vivo
    Edith Chorev
    Department of Neurobiology and Center for Computational Neuroscience, Hebrew University, Jerusalem 91904, Israel
    J Neurosci 27:5043-52. 2007
    ..The transient nature of these oscillatory epochs accounts for the difficulties to uncover them by prolonged recordings of complex spikes activity in the cerebellar cortex...
  37. ncbi Electrotonically mediated oscillatory patterns in neuronal ensembles: an in vitro voltage-dependent dye-imaging study in the inferior olive
    Elena Leznik
    Department of Physiology and Neuroscience, New York University School of Medicine, New York, New York 10016, USA
    J Neurosci 22:2804-15. 2002
    ..The possibility that such clustering is a consequence of intrinsic oscillations in ensembles of coupled neurons was tested using mathematical modeling...
  38. ncbi Characterization of peripheral circadian clocks in adipose tissues
    Sanjin Zvonic
    Stem Cell Laboratory, Louisiana State University, Pennington Biomedical Research Center, Baton Rouge, LA, USA
    Diabetes 55:962-70. 2006
    ....
  39. ncbi Refinement of metre perception--training increases hierarchical metre processing
    Eveline Geiser
    Massachusetts Institute of Technology, Department of Brain and Cognitive Sciences, Cambridge, MA 02139, USA
    Eur J Neurosci 32:1979-85. 2010
    ..Finally, our data show that small differences in sensitivity to higher-order patterns can be captured by means of an MMN paradigm...
  40. pmc Time-of-day-dependent dietary fat consumption influences multiple cardiometabolic syndrome parameters in mice
    M S Bray
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Obes (Lond) 34:1589-98. 2010
    ..Despite growing acceptance that biological rhythms profoundly influence energy homeostasis, little is known regarding how the timing of nutrient ingestion influences development of common metabolic diseases...
  41. ncbi Stuttering and the basal ganglia circuits: a critical review of possible relations
    Per A Alm
    Department of Clinical Neuroscience, Lund University, Lund, Sweden
    J Commun Disord 37:325-69. 2004
    ..Behavioral and pharmacologic information suggests the existence of subtypes of stuttering...
  42. ncbi Synchronization and rhythmic processes in physiology
    L Glass
    Department of Physiology, Centre for Nonlinear Dynamics in Physiology and Medicine, McGill University, Montreal, Quebec, Canada
    Nature 410:277-84. 2001
    ....
  43. ncbi Suprachiasmatic regulation of circadian rhythms of gene expression in hamster peripheral organs: effects of transplanting the pacemaker
    Hongnian Guo
    Department of Biology and Program in Neuroscience and Behavior, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Neurosci 26:6406-12. 2006
    ..Furthermore, the results indicate that conventional models of internal entrainment may need to be revised to explain control of the periphery by the pacemaker...
  44. ncbi Pattern motion selectivity of spiking outputs and local field potentials in macaque visual cortex
    Farhan A Khawaja
    Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
    J Neurosci 29:13702-9. 2009
    ..Together, these results suggest a surprisingly strong link between the sensory tuning of cortical LFPs and afferent inputs, with important implications for the interpretation of imaging studies and for models of cortical function...
  45. ncbi Acute changes in motor cortical excitability during slow oscillatory and constant anodal transcranial direct current stimulation
    Til Ole Bergmann
    Department of Neurology, Christian Albrechts University Kiel, D 24105 Kiel, Germany
    J Neurophysiol 102:2303-11. 2009
    ..We conclude that sleep slow oscillation-like excitability changes cannot be actively imposed on the awake cortex with so-tDCS, but phase-independent on-line as well as off-line facilitation can reliably be induced...
  46. ncbi Dopamine-dependent changes in the functional connectivity between basal ganglia and cerebral cortex in humans
    David Williams
    Sobell Department of Neurophysiology, Institute of Neurology, London, UK
    Brain 125:1558-69. 2002
    ....
  47. ncbi What keeps C. elegans regular: the genetics of defecation
    Robyn Branicky
    Department of Biology, McGill University, 1205 Docteur Penfield Avenue, Montreal, Quebec H3A 1B1, Canada
    Trends Genet 22:571-9. 2006
    ..Our review highlights how the function of a system even this simple results from the integration of many aspects of an organism's biology and involves the action of diverse genes...
  48. ncbi Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network
    Guillaume P Dugué
    Laboratoire de Neurobiologie, ENS, CNRS, Paris
    Neuron 61:126-39. 2009
    ..These results suggest a major role for Golgi cells in coordinating cerebellar sensorimotor integration during oscillatory interactions...
  49. ncbi The influence of metricality and modality on synchronization with a beat
    Aniruddh D Patel
    The Neurosciences Institute, 10640 John Jay Hopkins Drive, San Diego, CA 92121, USA
    Exp Brain Res 163:226-38. 2005
    ..This suggests that beat perception and synchronization have a special affinity with the auditory system...
  50. pmc Rhythm generation through period concatenation in rat somatosensory cortex
    Mark A Kramer
    Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, United States of America
    PLoS Comput Biol 4:e1000169. 2008
    ..We conclude that neural activity in the superficial and deep cortical layers may temporally combine to generate a slower oscillation...
  51. ncbi Quantitative analysis of high-frequency oscillations (80-500 Hz) recorded in human epileptic hippocampus and entorhinal cortex
    Richard J Staba
    Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    J Neurophysiol 88:1743-52. 2002
    ..The strong association between FR and regions of seizure initiation supports the view that FR reflects pathological hypersynchronous events crucially associated with seizure genesis...
  52. pmc EEG mu rhythm and imitation impairments in individuals with autism spectrum disorder
    R Bernier
    Department of Psychology, University of Washington, Seattle, WA 98185, USA
    Brain Cogn 64:228-37. 2007
    ..These findings suggest that there is execution/observation matching system dysfunction in individuals with autism and that this matching system is related to degree of impairment in imitation abilities...
  53. ncbi Bursting in leech heart interneurons: cell-autonomous and network-based mechanisms
    Gennady S Cymbalyuk
    Biology Department, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 22:10580-92. 2002
    ..Endogenous bursting, in turn, ensures appropriate bursting if the strength of mutual inhibition is weakened and limits the minimum period of the half-center oscillator to a period near that of the single neuron...
  54. ncbi Keeping with the beat: movement trajectories contribute to movement timing
    Ramesh Balasubramaniam
    Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham, Edgbaston, B15 2TT, UK
    Exp Brain Res 159:129-34. 2004
    ..We suggest that movement asymmetry in repetitive timing tasks helps satisfy requirements of precision and accuracy relative to a target event...
  55. ncbi A novel functional neuron group for respiratory rhythm generation in the ventral medulla
    Hiroshi Onimaru
    Showa University School of Medicine, Shinagawa ku, Tokyo 142 8555, Japan
    J Neurosci 23:1478-86. 2003
    ..Our findings suggest that the pFRG comprises a neuronal population that is involved in the primary respiratory rhythm generation in the rostrocaudally extending respiratory neuron network of the medulla...
  56. ncbi Developmental modulation of retinal wave dynamics: shedding light on the GABA saga
    Evelyne Sernagor
    School of Neurology, Neurobiology, and Psychiatry, Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, NE2 4HH, United Kingdom
    J Neurosci 23:7621-9. 2003
    ..Moreover, our results suggest that visual experience modulates the GABAergic switch...
  57. ncbi Modeling effects of rhythmic context on perceived duration: a comparison of interval and entrainment approaches to short-interval timing
    J Devin McAuley
    Scott Center for Neuroscience, Mind, and Behavior, Department of Psychology, Bowling Green State University, Ohio 43403, USA
    J Exp Psychol Hum Percept Perform 29:1102-25. 2003
    ..Findings are discussed in the context of theoretical assumptions about clock resetting, the representation of time, and independence of successive time intervals...
  58. pmc Visual and musculoskeletal underpinnings of anchoring in rhythmic visuo-motor tracking
    Melvyn Roerdink
    Research Institute MOVE, Faculty of Human Movement Sciences, VU University, Van der Boechorststraat 9, 1081BT, Amsterdam, The Netherlands
    Exp Brain Res 184:143-56. 2008
    ....
  59. ncbi What determines the frequency of fast network oscillations with irregular neural discharges? I. Synaptic dynamics and excitation-inhibition balance
    Nicolas Brunel
    Centre National de la Recherche Scientifique Neurophysique et Physiologie du Système Moteur Université Paris René Descartes, 75270 Paris Cedex 06, France
    J Neurophysiol 90:415-30. 2003
    ..Faster excitation than inhibition, or a higher excitation/inhibition ratio, favors the feedback loop and a much slower oscillation (typically in the gamma range)...
  60. ncbi Deletions of rhythmic motoneuron activity during fictive locomotion and scratch provide clues to the organization of the mammalian central pattern generator
    Myriam Lafreniere-Roula
    Spinal Cord Research Centre and Department of Physiology, University of Manitoba, Winnipeg, Manitoba, Canada
    J Neurophysiol 94:1120-32. 2005
    ....
  61. ncbi Rhythmic arm movement is not discrete
    Stefan Schaal
    Computer Science and Neuroscience, University of Southern California, Los Angeles, California 90089 2520, USA
    Nat Neurosci 7:1136-43. 2004
    ..These results provide neuroscientific evidence that rhythmic arm movement cannot be part of a more general discrete movement system and may require separate neurophysiological and theoretical treatment...
  62. ncbi Night-to-night variability of periodic leg movements during sleep in restless legs syndrome and periodic limb movement disorder: comparison between the periodicity index and the PLMS index
    Raffaele Ferri
    Sleep Research Centre, Department of Neurology I C, Oasi Institute for Research on Mental Retardation and Brain Aging IRCCS, Troina, Italy
    Sleep Med 14:293-6. 2013
    ..It is currently not known if this is also the case for the degree of periodicity of leg movements, quantified by the Periodicity index.
  63. pmc Temporal frequency of subthreshold oscillations scales with entorhinal grid cell field spacing
    Lisa M Giocomo
    Center for Memory and Brain, Department of Psychology, Program in Neuroscience, Boston University, 2 Cummington Street, Boston, MA 02215, USA
    Science 315:1719-22. 2007
    ....
  64. ncbi Synchronization of neuronal activity in the human primary motor cortex by transcranial magnetic stimulation: an EEG study
    T Paus
    Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada
    J Neurophysiol 86:1983-90. 2001
    ..As such, they corroborate previous studies of cortical oscillations in the motor cortex and point to the potential of the combined TMS/EEG approach for further investigations of cortical rhythms in the human brain...
  65. ncbi Rumination, negative cognition, and their interactive effects on depressed mood
    Jeffrey A Ciesla
    Department of Psychology, Kent State University, Kent, OH 44242, USA
    Emotion 7:555-65. 2007
    ..These studies provide support for an interactive model in which rumination amplifies the deleterious effects of negative cognition...
  66. ncbi Period basin of entrainment for unintentional visual coordination
    Stacy M Lopresti-Goodman
    Center for the Ecological Study of Perception and Action, University of Connecticut, Storrs, CT 06269, USA
    J Mot Behav 40:3-10. 2008
    ..The present findings extend the dynamical systems perspective on person-environment coupling and highlight the significance of period difference to the emergence of unintentional coordination...
  67. ncbi Treadmill walking as an external pacemaker to improve gait rhythm and stability in Parkinson's disease
    Silvi Frenkel-Toledo
    Department of Physical Therapy, Sackler School of Medicine, Tel Aviv, Israel
    Mov Disord 20:1109-14. 2005
    ....
  68. ncbi Large-scale comparative analysis of pertussis population dynamics: periodicity, synchrony, and impact of vaccination
    Hélène Broutin
    Research Unit 24, Epidemiology and Prevention, Institute of Research for Development, 911 Avenue Agropolis, BP 64501, 34394 Montpellier Cedex 5, France
    Am J Epidemiol 161:1159-67. 2005
    ..the wavelet method, a comparative analysis of pertussis time series in 12 countries to detect and quantify periodicity and synchrony between them...
  69. ncbi A 6- to 8-day periodicity in cercarial shedding occurred in some Galba truncatula experimentally infected with Fasciola hepatica
    P Vignoles
    UPRES EA 3174 USC INRA, Faculties of Pharmacy and Medicine, 87025 Limoges, France
    Parasitol Res 98:385-8. 2006
    ..The periodicity of 6.8-7...
  70. ncbi Neuronal periodicity detection as a basis for the perception of consonance: a mathematical model of tonal fusion
    Martin Ebeling
    Peter Cornelius Conservatory of Music, Monchengladbach D 55122 Mainz, Germany
    J Acoust Soc Am 124:2320-9. 2008
    ..the sensation of consonance and dissonance on the basis of neuronal coding and the properties of a neuronal periodicity detection mechanism...
  71. ncbi Whisker deafferentation and rodent whisking patterns: behavioral evidence for a central pattern generator
    P Gao
    Biopsychology Program, Hunter College, City University of New York, New York, New York 10021, USA
    J Neurosci 21:5374-80. 2001
    ..These findings provide strong behavioral evidence for a whisking CPG and are discussed in relation to its possible location and properties...
  72. pmc Polar localization of the CckA histidine kinase and cell cycle periodicity of the essential master regulator CtrA in Caulobacter crescentus
    Peter S Angelastro
    Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520 8103, USA
    J Bacteriol 192:539-52. 2010
    ..CtrA activity fluctuates during the cell cycle, and its periodicity is a key element of the engine that drives cell cycle progression...
  73. pmc Rhythm, timing and the timing of rhythm
    Amalia Arvaniti
    Department of Linguistics, University of California, San Diego, CA 92093 0108, USA
    Phonetica 66:46-63. 2009
    ..The hypothesis is advanced that these universal principles are grouping and prominence and evidence to support it is provided...
  74. ncbi Cerebellar cortical output encodes temporal aspects of rhythmic licking movements and is necessary for normal licking frequency
    Jeri L Bryant
    Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, USA
    Eur J Neurosci 32:41-52. 2010
    ....
  75. pmc Periodicity and evoked responses in motor cortex
    Jacob Reimer
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 30:11506-15. 2010
    Spiking in primary motor cortex (MI) exhibits a characteristic beta frequency periodicity, but the functional relevance of this rhythmic firing is controversial...
  76. ncbi Combining multisensory temporal information for movement synchronisation
    Alan M Wing
    Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Exp Brain Res 200:277-82. 2010
    ..Our findings indicate the need for further investigation of the MLE account of the integration of multisensory signals in the temporal control of action...
  77. ncbi Hippocampo-cerebellar theta band phase synchrony in rabbits
    J Wikgren
    Department of Psychology, University of Jyvaskyla, Jyvaskyla, Finland
    Neuroscience 165:1538-45. 2010
    ..Future studies should examine cerebellar unit activity in relation to hippocampal theta oscillations in order to discover the detailed mechanisms of theta-paced neural activity...
  78. ncbi The slow-wave components of the cyclic alternating pattern (CAP) have a role in sleep-related learning processes
    Raffaele Ferri
    Sleep Research Centre, Department of Neurology I C, Oasi Institute for Research on Mental Retardation and Brain Aging IRCCS, Via Conte Ruggero 73, Troina, Italy
    Neurosci Lett 432:228-31. 2008
    ..These results confirm our hypothesis that CAP slow components are modified by a learning task during the day preceding sleep and support the idea that these components may play a role in sleep-related cognitive processes...
  79. ncbi Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level
    Chris I De Zeeuw
    Department of Neuroscience, Medical Faculty, Erasmus MC, 3000DR Rotterdam, The Netherlands
    J Neurosci 23:4700-11. 2003
    ....
  80. ncbi Rhythmic movements are larger and faster but with the same frequency on removal of visual feedback
    S Levy-Tzedek
    Department of Biomedical Engineering, Ben Gurion University of the Negev, Beer Sheba, Israel
    J Neurophysiol 106:2120-6. 2011
    ....
  81. pmc The effect of diazepam on motor cortical oscillations and corticomuscular coherence studied in man
    Mark R Baker
    Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, UK
    J Physiol 546:931-42. 2003
    ..The relative constancy of coherence even when the amplitude of cortical oscillations is perturbed suggests that corticomuscular coherence itself may have a functional role in motor control...
  82. pmc Neural ensemble codes for stimulus periodicity in auditory cortex
    Jennifer K Bizley
    Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, and Robotics, Brain, and Cognitive Sciences Department, Italian Institute of Technology, 16163 Genova, Italy
    J Neurosci 30:5078-91. 2010
    ..in auditory cortex of male and female ferrets to artificial vowels of varying fundamental frequency (f(0)), or periodicity, and compared these with the performance of animals trained to discriminate the periodicity of these sounds...
  83. pmc Purinergic modulation of preBötzinger complex inspiratory rhythm in rodents: the interaction between ATP and adenosine
    J D Zwicker
    Departments of Physiology and Pediatrics, Centre for Neuroscience, Women and Children s Health Research Institute WCHRI, Faculty of Medicineand Dentistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7
    J Physiol 589:4583-600. 2011
    ..Data also suggest therapeutic potential may derive from methods that alter the ATP-ADO balance to favour the excitatory actions of ATP...
  84. ncbi Tripartite purinergic modulation of central respiratory networks during perinatal development: the influence of ATP, ectonucleotidases, and ATP metabolites
    Adrianne G Huxtable
    Department of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Neurosci 29:14713-25. 2009
    ....
  85. ncbi Neural modulation by regularity and passage of time
    Angel Correa
    Departamento de Psicologia Experimental y Fisiologia del Comportamiento, Universidad de Granada, Granada, Spain
    J Neurophysiol 100:1649-55. 2008
    ..This high degree of neural overlap between the effects of temporal orienting driven by rhythms and foreperiod effects associated with the passage of time suggests the involvement of a common mechanism for temporal preparation...
  86. ncbi Annual, lunar and diel reproductive periodicity of a spawning aggregation of snapper Pagrus auratus (Sparidae) in a marine embayment on the lower west coast of Australia
    C B Wakefield
    Western Australian Fisheries and Marine Research Laboratories, Department of Fisheries, Government of Western Australia, P O Box 20, North Beach, Western Australia 6920, Australia
    J Fish Biol 77:1359-78. 2010
    ..The reproductive cycles of P. auratus described in this study have assisted managers with the appropriate temporal and spatial scale for a closed fishing season to protect these spawning aggregations...
  87. pmc Spike integration and cellular memory in a rhythmic network from Na+/K+ pump current dynamics
    Stefan R Pulver
    Brandeis University, Department of Biology, National Center of Behavioral Genomics and Volen Center for Complex Systems, Waltham, Massachusetts, USA
    Nat Neurosci 13:53-9. 2010
    ..This current also interacted with endogenous Shal K(+) conductances to modulate spike timing for multiple seconds following rhythmic activity, providing a cellular memory of network activity on a behaviorally relevant timescale...
  88. ncbi Two different processes for sensorimotor synchronization in continuous and discontinuous rhythmic movements
    Kjerstin Torre
    Sensorimotor Neuroscience Laboratory, McMaster University, Hamilton, ON, L8S 2K1, Canada
    Exp Brain Res 199:157-66. 2009
    ..We suggest that the two modeling frameworks indeed account for different synchronization processes involved in the process of keeping time with the beat...
  89. pmc Ca2+-regulated-cAMP/PKA signaling in cardiac pacemaker cells links ATP supply to demand
    Yael Yaniv
    Laboratory of Cardiovascular Science, Gerontology Research Center, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland 21224 6825, USA
    J Mol Cell Cardiol 51:740-8. 2011
    ..ATP is consumed to pump Ca(2+) to the SR, to produce cAMP, to support contraction and to maintain cell ionic homeostasis...
  90. ncbi On the spectral periodicity of transient-evoked otoacoustic emissions from normal and damaged cochleas
    P Avan
    Laboratory of Sensory Biophysics, School of Medicine, Clermont Ferrand, France
    J Acoust Soc Am 108:1117-27. 2000
    The spectral quasi-periodicity of transient-evoked otoacoustic emissions (TEOAE) is well acknowledged since Zwicker described a preferred spacing of 0...
  91. ncbi Fictive swimming motor patterns in wild type and mutant larval zebrafish
    Mark A Masino
    Cornell Univ, Dept of Neurobiology and Behavior, W101 Mudd Hall, Ithaca, NY 14853, USA
    J Neurophysiol 93:3177-88. 2005
    ....
  92. ncbi No temporal association between influenza outbreaks and invasive pneumococcal infections
    Andre Michael Toschke
    Institute for Social Pediatrics and Adolescent Medicine, Ludwig Maximilians University Munich, Munich, Germany
    Arch Dis Child 93:218-20. 2008
    ..To assess whether the influenza peak in populations precedes the annual peak for invasive pneumococcal infections (IPI) in winter...
  93. ncbi Are the electroencephalograms mainly rhythmic? Assessment of periodicity in wide-band time series
    T H Bullock
    Department of Neurosciences, School of Medicine and Neurobiology Unit 0240, Scripps Institution of Oceanography, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Neuroscience 121:233-52. 2003
    ..peaks in the two spectra agree most of the time, quite often a peak in the power spectrum accompanies no periodicity peak and some periodicity peaks have no power spectral peak...
  94. ncbi Strong genetic differentiation and postglacial origin of populations in the marine midge Clunio marinus (Chironomidae, Diptera)
    Tobias S Kaiser
    Max Planck Institute for Chemical Ecology, Hans Knoll Strasse 8, D 07745 Jena, Germany
    Mol Ecol 19:2845-57. 2010
    ....
  95. ncbi Glia contribute to the purinergic modulation of inspiratory rhythm-generating networks
    Adrianne G Huxtable
    Departments of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Neurosci 30:3947-58. 2010
    ..Data reveal a role for glia in signal processing within brainstem motor networks that may be relevant to similar networks throughout the neuraxis...
  96. pmc Optimal control of a hybrid rhythmic-discrete task: the bouncing ball revisited
    Renaud Ronsse
    Department of Electrical Engineering and Computer Science, Montefiore Institute, Universite de Liege, Liege, Belgium
    J Neurophysiol 103:2482-93. 2010
    ..Matching results of model simulations give support to a hybrid control model based on optimality, and therefore suggest that optimality principles are applicable to the sensorimotor control of complex movements such as ball bouncing...
  97. ncbi Two distinct types of noisy oscillators in electroreceptors of paddlefish
    Alexander B Neiman
    Center for Neurodynamics, Department of Physics and Astronomy, University of Missouri, St Louis 63121 4499, USA
    J Neurophysiol 92:492-509. 2004
    ..Having 2 distinct types of internal oscillators is a novel form of organization for peripheral sensory receptors, of relevance for other hair cell sensory receptors...
  98. ncbi Models of stochastic biperiodic oscillations and extended serial correlations in electroreceptors of paddlefish
    Alexander B Neiman
    Department of Physics and Astronomy, Ohio University, Ohio 45701, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 71:061915. 2005
    ....
  99. ncbi Discrete and cyclical movements: unified dynamics or separate control?
    Anke M van Mourik
    Institute for Fundamental and Clinical Human Movement Sciences, Free University, Amsterdam, The Netherlands
    Acta Psychol (Amst) 117:121-38. 2004
    ..Future modeling attempts should explicate the dynamics of initiation and abortion of both discrete and cyclical movements...
  100. ncbi New roles for the gamma rhythm: population tuning and preprocessing for the Beta rhythm
    Mette S Olufsen
    Department of Mathematics, North Carolina State University, Raleigh, NC 27659 8205, USA
    J Comput Neurosci 14:33-54. 2003
    ..We present experimental evidence showing that such a separation can occur in hippocampal slices...
  101. ncbi Spatial and temporal regulation of mitogen-activated protein kinase phosphorylation in the mouse suprachiasmatic nucleus
    Michio Nakaya
    Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Science Bldg 3, Room 218A, 2 11 16 Yayoi, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Biochem Biophys Res Commun 305:494-501. 2003
    ..Thus, the mode of circadian and photic regulation of MAPK phosphorylation varies remarkably among the three subregions within the SCN, suggesting divergent and cell type-specific roles of MAPK in the clock system of the mouse SCN...

Research Grants65

  1. The Role of Circadian Periodicity in Human Cardiovascular Disease and Diabetes
    John P Forman; Fiscal Year: 2013
    ..Our project may help provide a framework for innovative approaches in cardiovascular disease and diabetes treatment and prevention. ..
  2. NEUROSECRETORY GENE EXPRESSION IN THE HYPOTHALAMUS
    Pamela L Mellon; Fiscal Year: 2011
    ..Astonishingly, GT1 cells secrete GnRH in a pulsatile fashion with a 30 min periodicity mirroring mouse GnRH neurons in vivo...
  3. Sleep, Arousal, and Spontaneous Movements in Opioid Exposed Infants
    Marie J Hayes; Fiscal Year: 2010
    ..G3, n=20) will be compared to exposure groups using algorithms developed in our laboratory to detect the periodicity and bout structure of spontaneous movements (SM) a putative autonomic probe of arousal regulatory integrity...
  4. TRH REGULATION/BIOSYNTHESIS AND PARAVENTRICULAR NUCLEUS
    RONALD MICHAEL LECHAN; Fiscal Year: 2010
    ..from leptin- responsive arcuate nucleus neurons and the subparaventricular zone to give rise to the circadian periodicity of the HPT axis...
  5. Developing cell lines from clock neurons in Drosophila
    Paul E Hardin; Fiscal Year: 2013
    ..Aim 2 we will determine whether these cell lines display the cardinal clock properties of self-sustained ~24h periodicity, phase shifting by environmental cues, and periods that are essentially invariant at different temperatures, ..
  6. CIRCADIAN-COUPLED CELLULAR AND LUNG FUNCTION IN COPD
    Irfan Rahman; Fiscal Year: 2012
    ..in mouse lungs;(2) determine the mechanisms whereby SIRT1 regulates BMAL1, inflammatory response and circadian periodicity by CS;and (3) determine the role of circadian proteins and SIRT1 on CS-mediated alteration in circadian ..
  7. Strategies for mapping origins in mammalian genomes
    JOYCE HAMLIN; Fiscal Year: 2009
    ..appear to correspond to single sites or circumscribed zones will be analyzed for common compositional bias, periodicity, fold-back potential, DNA unwinding elements, and conventional sequence motifs to uncover commonalities that ..
  8. Cycling of Circadian Rhythm Proteins
    Amita Sehgal; Fiscal Year: 2013
    ..However, the mechanisms that maintain such feedback loops with a 24 hour periodicity are not understood...
  9. Investigating Genetics of Human Natural Short Sleepers
    Ying Hui Fu; Fiscal Year: 2013
    ..Sleep is controlled by at least two processes: a circadian pacemaker (the clock) ticking with periodicity of ~24 hours, and a homeostatic drive that increases during wakefulness and dissipates during sleep...
  10. Structure/Function Studies of Mammalian Circadian Clock Proteins
    Carla B Green; Fiscal Year: 2013
    ..Recent years have produced molecular models of how the circadian clock is built and how it maintains 24-hour periodicity. It is known that the core part of this clockwork is a negative feedback of transcription/translation whereby ..
  11. Structural Biology of the S. elongatus Circadian Clock
    Martin Egli; Fiscal Year: 2013
    ..translational and post-translational feedback loops (TTFLs) to achieve gene expression with circadian periodicity. We study the components of the biological clock in the prokaryotic cyanobacterium, Synechococcus elongatus, ..
  12. Cell Cycle Regulation in Caulobacter Crescentus
    Michael Laub; Fiscal Year: 2013
    ..However, CtrA does not significantly influence the fundamental periodicity of DNA replication...
  13. DETERMINATION AND EXPRESSION OF AMELOGENIN GENE PRODUCTS
    Malcolm L Snead; Fiscal Year: 2012
    ..In situ hybridization of in vivo developing mouse incisors identified a periodicity for amelogenin transcript accumulation wherein one sagittal row of ameloblasts contained numerous amelogenin ..
  14. Analysis of EGFR-dependent sleep in C. elegans
    CHERYL LYNN VAN BUSKIRK; Fiscal Year: 2013
    ..elegans sleep behavior, which occurs rhythmically with molting rather than with circadian periodicity. We will examine LIN-3 expression for oscillation with the molting cycle, to connect behavior with ..
  15. CIRCADIAN CLOCK DYSFUNCTION AS A MEDIATOR OF NEURODEGENERATION
    ERIK STEVEN MUSIEK; Fiscal Year: 2013
    ..clock) that is present in most cells in the body, including neurons and glia, and oscillates with a 24 hour periodicity. In many tissues, circadian clocks serve as master regulators of metabolism, aging, and oxidative stress, ..
  16. TRAINING IN METHODS OF COMPUTATIONAL NEUROSCIENCE
    William S Reznikoff; Fiscal Year: 2013
    ..neuroscience are beginning to shed light on the basis of neuropsychiatric and neurological diseases exhibiting periodicity or cyclicity which include Bipolar Disorder, Schizophrenia, Seasonal Affective Disorder, Klein-Levin Syndrome, ..
  17. Post-translational control mechanisms of the circadian clock
    David E Somers; Fiscal Year: 2013
    ..which may contribute substantially to establishing the timing delays necessary to establishing a 24 h molecular periodicity. We have identified a nuclear pore component that slows the circadian clock when absent...
  18. DNA Excision Repair and DNA Damage Checkpoints
    Aziz Sancar; Fiscal Year: 2013
    ..excision repair in mammals have revealed that excision repair exhibits high amplitude oscillation with a daily periodicity in most mouse tissues...
  19. Electrophysiological and psychophysical measures of auditory temporal processing
    Sara K Mamo; Fiscal Year: 2013
    ..Aim 1 will employ auditory brainstem response measures elicited by speech as an index of periodicity coding...
  20. MOLECULAR AND CELLULAR STUDIES OF CIRCADIAN RHYTHMS
    Michael W Young; Fiscal Year: 2013
    ..Additional studies have identifed new genes and proteins affecting periodicity of the circadian clock...
  21. Melatonin: pacemaker for nocturnal periodicity of microfilarial parasites
    JEFFERSON ARCHER VAUGHAN; Fiscal Year: 2012
    ..Throughout most of their geographic range, W. bancrofti and B. malayi exhibit nocturnal periodicity - that is, the mf only become abundant in peripheral blood during the middle of the night...
  22. Ventricular Fibrillation in a Globally Ischemic Heart: From Cell to ECG
    Alexey V Zaitsev; Fiscal Year: 2012
    ..translates into a progressive disorganization of propagating wavelets and explains the progressive loss of periodicity in the ECG waveform. The specific aims are: 1...
  23. Photopolymerization-Induced Topography Directs Neurite and Schwann Cell Alignment
    Marlan R Hansen; Fiscal Year: 2013
    ..control afforded by PP will be leveraged to fabricate parallel line-space gratings with varied amplitude, periodicity, and surface nanoroughness...
  24. Processing AM signals in the auditory system.
    Gary J Rose; Fiscal Year: 2013
    ..In a number of vertebrate species, including mammals, there is a transformation from a periodicity coding of the rate of amplitude modulation to an AM filter representation;most neurons in the midbrain respond ..
  25. Allosteric Regulation of Myocardial Contraction
    JOHN MARSHALL ROBINSON; Fiscal Year: 2013
    ..Ca2+ sensitivity-The contractility and periodicity of the heart is regulated on a beet-to-beet basis to meet the needs of demands of the body for perfused blood...
  26. Longitudinal Voice Patterns in Bipolar Disorder
    Melvin G McInnis; Fiscal Year: 2013
    ..It is an illness with pathological disruptions of emotion, cognitive and motor capacity. There is a periodicity of the illness pattern that oscillates between manic energized states with charged emotions and pressured rapid ..
  27. Identifying the neural mechanisms for learning hippocampal spatial maps
    MARK PAUL BRANDON; Fiscal Year: 2013
    ..muscimol inactivation of the medial septum simultaneously eliminates theta oscillations and grid cell spatial periodicity (see Figure 1 in dissertation summary)...
  28. SPEECH SOUND PROCESSING IN AUDITORY CORTEX
    Mitchell Steinschneider; Fiscal Year: 2013
    ..operate on neural representations of harmonic structure (rate- place profiles) or F0-related periodicities (periodicity-place profiles), respectively...
  29. Effects of sensorineural loss on robust speech coding
    Michael Heinz; Fiscal Year: 2007
    ..If different effects of SNHL on periodicity and temporal-place measures of F0 were observed in the AN and CN, this result would constrain the possible ..
  30. Processing AM signals in the auditory system
    GARY ROSE; Fiscal Year: 2009
    ..In a number of vertebrate species, including mammals, there is a transformation from a periodicity coding of the rate of amplitude modulation to an AM filter representation;most neurons in the midbrain respond ..
  31. High-Speed, Depth-Resolved Images of Cardiac physiology
    Guy Salama; Fiscal Year: 2007
    ..regarding the precise inputs to the node (fast and slow pathways), mechanisms of AVN reentry, Wenckebach periodicity and Wolf-Parkinson syndrome...
  32. Structural Determinants of TCR Assembly and Signaling
    Kai W Wucherpfennig; Fiscal Year: 2013
    ..The absence of an alpha-helical periodicity of these protein-lipid interactions further suggests that the actual conformation of the ITAM is distinct from ..
  33. TRH REGULATION/BIOSYNTHESIS AND PARAVENTRICULAR NUCLEUS
    RONALD LECHAN; Fiscal Year: 2007
    ..integrates signals from the arcuate nucleus and subparaventricular zone that are responsible for the circadian periodicity of the HPT axis...
  34. Complex Pattern Detection by the Retina
    Michael J Berry; Fiscal Year: 2011
    ..data showing that the retina can quickly learn simple patterns in the visual stimulus, such as a temporal periodicity or a smooth motion trajectory, so that a subset of ganglion cells fires selectively after a violation of the ..
  35. STRUCTURE OF ADENOSINE RECEPTORS
    Jack Wells; Fiscal Year: 2002
    ..The periodicity of reactive cysteines will provide insights concerning the structural nature of the TM...
  36. BIOLOGY OF CHROMOSOME 17 LINKED DEMENTIA WITH TAUOPATHY
    Jill Murrell; Fiscal Year: 2000
    ..filaments isolated from brains of affected family members were composed of tau and differed in diameter and periodicity from the paired helical filaments of Alzheimer's disease...
  37. CHROMATIN-TELOMERE STRUCTURE AND AT GENOMIC SENSITIVITY
    TEJ PANDITA; Fiscal Year: 2005
    ..We demonstrated that altered telomere nuclear matrix interactions and nucleosomal periodicity observed in cells derived from individuals with ataxia telangiectasia could be the reason for telomere erosion...
  38. STUDIES ON CLOSTRIDIUM SEPTICUM LETHAL TOXIN
    Rodney Tweten; Fiscal Year: 2003
    ..with the membrane via either an amphipathic beta sheet or an alpha helix they will observe a difference in the periodicity of the response from both assays...
  39. Regulation of Myofibrillogenesis by Calcium Signaling
    Michael Ferrari; Fiscal Year: 2004
    ..transients are necessary for A band assembly, it is unknown if they are also required for establishing Z-ljne periodicity or formation of actin bands (Aim 3)...
  40. Immunomagnetic Diffractometry for Rapid Biomolecular Detection
    Cagri Savran; Fiscal Year: 2009
    ..bead size, grating periodicity, surface material, refractive indices) for maximum sensitivity...
  41. MATERNAL INFLUENCE ON DEVELOPING 24-HOUR PERIODICITY
    STEVEN REPPERT; Fiscal Year: 1991
    ..The results of these studies will advance our knowledge of the mechanisms and physiological significance of light perception by the mammalian fetus...
  42. Tertiary Structures of Circadian Clock Proteins by NMR
    Andy LiWang; Fiscal Year: 2006
    DESCRIPTION: (provided by applicant) The physiology and behavior of virtually all organisms oscillate with a periodicity of approximately 24 h, which is now known to be the result of an endogenous oscillator called the circadian clock...
  43. DNA CONFORMATION AND ENEDIYNE TARGET RECOGNITION
    Peter Dedon; Fiscal Year: 1999
    ..that will be tested by statistical sequencing of damage sites in nucleosomal DNA and by analysis of the periodicity of damage sites in long tracts of defined- sequence DNA...
  44. SPATIO-TEMPORAL PERIODICITY IN ARTIAL FIBRILLATION
    JOSE JALIFE; Fiscal Year: 2006
    ..Accomplishment of the proposed studies should lead to an increased understanding of the mechanisms of AF at the molecular, cellular and organ levels and may lead to therapeutic advances. [unreadable] [unreadable]..
  45. NEUROETHOLOGY OF VOCAL COMMUNICATION IN ANURANS
    Andrea Simmons; Fiscal Year: 1999
    ..Competing hypotheses of how the periodicity or pitch of complex sounds is extracted in the central nervous system using different time domain algorithms ..
  46. PATHOGENESIS OF OSTEOGENESIS IMPERFECTA
    Velidi Rao; Fiscal Year: 1993
    ..This hypothesis predicts the existence of sets of homologous mutations, related by a simple D-stagger periodicity, which produce similar clinical phenotypic effects, ie. mild, moderate, severe or lethal OI...
  47. DEPRESSION, PEPTIDES AND STEROIDS IN CUSHING'S SYNDROME
    MONICA STARKMAN; Fiscal Year: 1990
    ..proportion of patients with primary depressive disorder show cortisol hypersecretion, flattened circadian periodicity, failure to suppress plasma cortisol with the overnight dexamethasone test, increased ACTH levels, and/or ..
  48. PROCISE cLC Sequencing System 2 Cart w/PC
    David Teplow; Fiscal Year: 2004
    ..facto radiolabeled protein samples to identify positions of specific amino acids through the periodicity of radioactivity detected in each cycle of the Edman chemistry...
  49. Respiratory Peridocity and Cognitive Decline in Elders
    Barbara Carlson; Fiscal Year: 2006
    ..Sleep is a period of increased risk for hypoxic events; and low respiratory periodicity may be an important indicator for identifying individuals with low cerebral oxygenation during sleep...
  50. ANTHRACYCLINE CARDIOTOXICITY--OXIDATIVE STRESS
    Narine Sarvazyan; Fiscal Year: 2002
    ..of the protein kinase C epsilon isoform from cytosol to myofibrils, and 3) detected disruption of the periodicity of actin staining after repetitive exposure of myocytes to clinically relevant drug concentrations...
  51. GENETICALLY ENGINEERED POLYMER FOR GENE DELIVERY
    HARNIDREZA GHANDEHARI; Fiscal Year: 1999
    ..this technology provides a unique means to synthesize biopolymers with sell defined properties such as charge periodicity, molecular weight, and three dimensional structure, and allows for the precise introduction of of informational ..
  52. EPIDEMIOLOGY OF HHV6 INFECTION IN PREGNANCY AND INFANCY
    Charles Leach; Fiscal Year: 1999
    ..Serum antibody levels will also be determined. The periodicity and factors for viral shedding will be determined. Cross- sectional planning and gynecology clinics at UHCD...
  53. STRUCTURAL ASPECTS OF ION CHANNEL FUNCTION
    Michael White; Fiscal Year: 1999
    ..From the periodicity (in terms of amino acid position) of the introduction of a binding site the secondary structure of the pore can ..
  54. MARROW REGULATION IN CYCLIC HEMATOPOIESIS
    David Dale; Fiscal Year: 2003
    ..and analogous autosomal recessive disease occurs in grey collie dogs whose blood cells oscillate with 14-day periodicity. This group has previously characterized the clinical and physiological features of this disease and its ..
  55. SUNDOWN SYNDROME IN A SKILLED NURSING FACILITY
    Donald Bliwise; Fiscal Year: 2002
    ..involves the brain region known to control the timing of sleep/wakefulness, rest/activity and the 24-hour periodicity of nearly all physiologic functions, including the diurnal body temperature cycle...
  56. AUTOMATIC ANALYSIS AND DIAGNOSIS OF DYSARTHRIA
    Karen Chenausky; Fiscal Year: 1999
    ..The system will make its judgement from acoustic features like periodicity of glottal pulses or rate and regularity of diadochokinetic syllables, and others...
  57. CODING OF PERIODICITY PITCH IN THE AUDITORY PATHWAY
    Peter Cariani; Fiscal Year: 2000
    ..The goal of this project is to investigate how the auditory system represents the pitch of complex sounds ("periodicity pitch") in the discharge patterns of central auditory neurons...
  58. The biology of striae of Retzius in human tooth enamel
    Rebecca Ferrell; Fiscal Year: 2007
    ..They occur with a constant periodicity in an individual's teeth, but periodicity varies across individuals with a range of 6 to 12 days...
  59. AMPHIPATHIC STRUCTURES IN GABA TRANSPORT
    Steven King; Fiscal Year: 2002
    ..3) to test the hypotheses that CAR contains a long polar face that can be disrupted by offsetting helical periodicity via Ala-insertion mutagenesis, and to test (via sulfhydryl-specific site-directed radiolabeling) the sub-..
  60. Insulin granule dynamics in pancreatic beta cells
    Robert Chow; Fiscal Year: 2005
    ..In health, approximately 75 percent of secreted insulin is released in discrete pulses with a periodicity of approximately 6 minutes, and modulation of the magnitude of these pulses serves to regulate the insulin ..
  61. MECHANISMS OF TRANSMITTER RELEASE BY COCHLEAR HAIR CELLS
    Thomas Parsons; Fiscal Year: 2006
    ..locking at the cochlear hair cell afferent fiber (CHC-AF) synapse, especially when acoustic stimuli occur with periodicity less than 1 ms. We propose to use a variety of experimental preparations from a single species to: 1...
  62. CIRCADIAN RHYTHM PROTEINS PER AND TIM
    Amita Sehgal; Fiscal Year: 1999
    ..that the per and tim proteins regulate each other and interactions between them control the phase and the periodicity of behavioral rhythms...
  63. COMPUTER ANALYSES OF EEG SLEEP IN PRETERM NEONATES
    Mark Scher; Fiscal Year: 1993
    ..by a corrected term age, and can be expressed by computer analysis in terms of spectral power, coalescence, and periodicity. These mathematical models reflect the degree of neurophysiological organization of the central nervous system ..
  64. MATHEMATICAL ANALYSIS OF BRAIN FUNCTION
    Ehud Kaplan; Fiscal Year: 2002
    ..together with the retinotopic map. We shall measure the periodicity of, and correlations among, the functional maps, to determine if they are commensurate...
  65. COLOR, LUMINANCE, AND MOTION PROCESSING IN CORTEX
    MORRIS CRAWFORD; Fiscal Year: 1992
    ..and luminance-contrast stimulation; (3) By scanning microdensitometry, examine in detail the pattern periodicity following color or luminance visual stimulation; (4) By microdensitometry, examine the cortical mosaics ..