Summary: Motion of a rigid body in which either one point is fixed, or all the points on a straight line are fixed. It is also the motion of a particle about a fixed point. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Top Publications

  1. ncbi Neuroimaging studies of mental rotation: a meta-analysis and review
    Jeffrey M Zacks
    Department of Psychology, Washington University in Saint Louis, Saint Louis, MO, USA
    J Cogn Neurosci 20:1-19. 2008
  2. pmc The bacterial actin MreB rotates, and rotation depends on cell-wall assembly
    Sven van Teeffelen
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 108:15822-7. 2011
  3. ncbi Direct observation of DNA rotation during transcription by Escherichia coli RNA polymerase
    Y Harada
    Department of Physics, Faculty of Science and Technology, Keio University, Hiyoshi 3 14 1, Kohoku Ku, Yokohama 223 8522, Japan
    Nature 409:113-5. 2001
  4. pmc Spontaneous intersubunit rotation in single ribosomes
    Peter V Cornish
    Department of Physics, University of Illinois, 1110 West Green Street, Urbana, IL 61801, USA
    Mol Cell 30:578-88. 2008
  5. ncbi Rotational head kinematics in football impacts: an injury risk function for concussion
    Steven Rowson
    School of Biomedical Engineering and Sciences, Virginia Tech Wake Forest University, 440 ICTAS Building, Stanger St, Blacksburg, VA 24061, USA
    Ann Biomed Eng 40:1-13. 2012
  6. ncbi Model for growth hormone receptor activation based on subunit rotation within a receptor dimer
    Richard J Brown
    Institute for Molecular Bioscience and School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, Australia
    Nat Struct Mol Biol 12:814-21. 2005
  7. ncbi p53 searches on DNA by rotation-uncoupled sliding at C-terminal tails and restricted hopping of core domains
    Tsuyoshi Terakawa
    Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606 8502 Japan
    J Am Chem Soc 134:14555-62. 2012
  8. ncbi Vestibular perception and action employ qualitatively different mechanisms. I. Frequency response of VOR and perceptual responses during Translation and Tilt
    Daniel M Merfeld
    Jenks Vestibular Physiology Laboratory, Massachusetts Eye and Ear Infirmary, Room 421, MEEI, 243 Charles St, Boston, Massachusetts 02114, USA
    J Neurophysiol 94:186-98. 2005
  9. ncbi UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila
    Gina Lee
    National Creative Research Initiatives Center and School of Biological Sciences, Seoul National University, Seoul, Korea
    Dev Biol 356:588-97. 2011
  10. ncbi ATP synthase--a marvellous rotary engine of the cell
    M Yoshida
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Yokohama 226 8503, Japan
    Nat Rev Mol Cell Biol 2:669-77. 2001

Detail Information

Publications374 found, 100 shown here

  1. ncbi Neuroimaging studies of mental rotation: a meta-analysis and review
    Jeffrey M Zacks
    Department of Psychology, Washington University in Saint Louis, Saint Louis, MO, USA
    J Cogn Neurosci 20:1-19. 2008
    Abstract Mental rotation is a hypothesized imagery process that has inspired controversy regarding the substrate of human spatial reasoning...
  2. pmc The bacterial actin MreB rotates, and rotation depends on cell-wall assembly
    Sven van Teeffelen
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 108:15822-7. 2011
    ..previous studies have suggested that MreB dynamics are driven by its own polymerization, we show that MreB rotation does not depend on its own polymerization but rather requires the assembly of the peptidoglycan cell wall...
  3. ncbi Direct observation of DNA rotation during transcription by Escherichia coli RNA polymerase
    Y Harada
    Department of Physics, Faculty of Science and Technology, Keio University, Hiyoshi 3 14 1, Kohoku Ku, Yokohama 223 8522, Japan
    Nature 409:113-5. 2001
    Helical filaments driven by linear molecular motors are anticipated to rotate around their axis, but rotation consistent with the helical pitch has not been observed...
  4. pmc Spontaneous intersubunit rotation in single ribosomes
    Peter V Cornish
    Department of Physics, University of Illinois, 1110 West Green Street, Urbana, IL 61801, USA
    Mol Cell 30:578-88. 2008
    ..Furthermore, the acylation state of P site tRNA has a dramatic effect on the frequency of intersubunit rotation. Our results provide direct evidence that the intersubunit rotation that underlies ribosomal translocation is ..
  5. ncbi Rotational head kinematics in football impacts: an injury risk function for concussion
    Steven Rowson
    School of Biomedical Engineering and Sciences, Virginia Tech Wake Forest University, 440 ICTAS Building, Stanger St, Blacksburg, VA 24061, USA
    Ann Biomed Eng 40:1-13. 2012
    ..These data provide an increased understanding of the biomechanics associated with concussion and they provide critical insight into injury mechanisms, human tolerance to mechanical stimuli, and injury prevention techniques...
  6. ncbi Model for growth hormone receptor activation based on subunit rotation within a receptor dimer
    Richard J Brown
    Institute for Molecular Bioscience and School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, Australia
    Nat Struct Mol Biol 12:814-21. 2005
    ..However, the receptor can be activated by rotation without ligand by inserting a defined number of alanine residues within the transmembrane domain...
  7. ncbi p53 searches on DNA by rotation-uncoupled sliding at C-terminal tails and restricted hopping of core domains
    Tsuyoshi Terakawa
    Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606 8502 Japan
    J Am Chem Soc 134:14555-62. 2012
    ..salt concentrations finding that, at physiological salt concentration, p53 diffuses along nonspecific DNA via rotation-uncoupled sliding with its CTD, whereas the core domain repeats dissociation and association...
  8. ncbi Vestibular perception and action employ qualitatively different mechanisms. I. Frequency response of VOR and perceptual responses during Translation and Tilt
    Daniel M Merfeld
    Jenks Vestibular Physiology Laboratory, Massachusetts Eye and Ear Infirmary, Room 421, MEEI, 243 Charles St, Boston, Massachusetts 02114, USA
    J Neurophysiol 94:186-98. 2005
    ..005-0.7 Hz) subjects in roll about an earth-horizontal, head-centered, rotation axis ("Tilt") or sinusoidally accelerating (3.3 m/s2, 0.005-0...
  9. ncbi UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila
    Gina Lee
    National Creative Research Initiatives Center and School of Biological Sciences, Seoul National University, Seoul, Korea
    Dev Biol 356:588-97. 2011
    Heterotaxy characterized by abnormal left-right body asymmetry causes diverse congenital anomalies. Organ rotation is a crucial developmental process to establish the left-right patterning during animal development...
  10. ncbi ATP synthase--a marvellous rotary engine of the cell
    M Yoshida
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Yokohama 226 8503, Japan
    Nat Rev Mol Cell Biol 2:669-77. 2001
    ..The mechanisms by which rotation and catalysis are coupled in the working enzyme are now being unravelled on a molecular scale.
  11. pmc Adaptation to visuomotor rotation through interaction between posterior parietal and motor cortical areas
    Hirokazu Tanaka
    Howard Hughes Medical Institute, Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, USA
    J Neurophysiol 102:2921-32. 2009
    Studying how motor adaptation to visuomotor rotation for one reach direction generalizes to other reach directions can provide insight into how visuomotor maps are represented and learned in the brain...
  12. ncbi Mental rotation of objects versus hands: neural mechanisms revealed by positron emission tomography
    S M Kosslyn
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Psychophysiology 35:151-61. 1998
    Twelve right-handed men participated in two mental rotation tasks as their regional cerebral blood flow (rCBF) was monitored using positron emission tomography...
  13. ncbi NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha
    Monique van der Voet
    Developmental Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Nat Cell Biol 11:269-77. 2009
    ..Spindle rotation during maternal meiosis is independent of GPR-1/2 and Galpha, yet requires LIN-5, ASPM-1, CMD-1 and dynein...
  14. ncbi Flexion and rotation of the trunk and lifting at work are risk factors for low back pain: results of a prospective cohort study
    W E Hoogendoorn
    TNO Work and Employment, Hoofddorp, The Netherlands
    Spine (Phila Pa 1976) 25:3087-92. 2000
    ..A 3-year prospective cohort study among workers of 34 companies in the Netherlands...
  15. pmc Internal rotation of the tibial component is frequent in stiff total knee arthroplasty
    Martin Bédard
    Department of Orthopaedic Surgery, CHA Hôpital de l Enfant Jésus, Laval University, Quebec City, QC, Canada
    Clin Orthop Relat Res 469:2346-55. 2011
    ..We suspected internally rotated components compromised motion because of pain, patellar maltracking, a tight medial flexion gap, and limited femoral rollback on a conforming lateral tibial condyle...
  16. pmc Cell entry of one-dimensional nanomaterials occurs by tip recognition and rotation
    Xinghua Shi
    School of Engineering, Brown University, Providence, Rhode Island 02912, USA
    Nat Nanotechnol 6:714-9. 2011
    ..nanotubes with end caps or carbon shells at their tips, uptake involves tip recognition through receptor binding, rotation that is driven by asymmetric elastic strain at the tube-bilayer interface, and near-vertical entry...
  17. ncbi Mental rotation of body parts and non-corporeal objects in patients with idiopathic cervical dystonia
    Mirta Fiorio
    Department of Neurological and Vision Sciences, Section of Rehabilitative Neurology, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy
    Neuropsychologia 45:2346-54. 2007
    Mental rotation of body parts is performed through inner simulation of actual movements, and is likely to rely upon cortical and subcortical systems (e.g...
  18. ncbi Microsaccades and blinks trigger illusory rotation in the "rotating snakes" illusion
    Jorge Otero-Millan
    Barrow Neurological Institute, Phoenix, Arizona 85013, USA
    J Neurosci 32:6043-51. 2012
    ..Here, we asked human subjects to indicate the presence or absence of rotation during the observation of the illusion while we simultaneously recorded their eye movements with high precision...
  19. ncbi Control of ribosomal subunit rotation by elongation factor G
    Arto Pulk
    Department of Molecular and Cell Biology, California Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720, USA
    Science 340:1235970. 2013
    ..RNAs and messenger RNA by one codon after each peptide bond is formed, a reaction that requires ribosomal subunit rotation and is catalyzed by the guanosine triphosphatase (GTPase) elongation factor G (EF-G)...
  20. ncbi Rotation and structure of FoF1-ATP synthase
    Daichi Okuno
    Department of Applied Chemistry, School of Engineering, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    J Biochem 149:655-64. 2011
    ..motors interconvert the chemical energy of ATP hydrolysis and proton electrochemical potential via the mechanical rotation of the rotary shaft. This unique energy transmission mechanism is not found in other biological systems...
  21. ncbi Sex differences in mental rotation and line angle judgments are positively associated with gender equality and economic development across 53 nations
    Richard A Lippa
    Department of Psychology, California State University, Fullerton, Fullerton, CA 92834 6846, USA
    Arch Sex Behav 39:990-7. 2010
    Mental rotation and line angle judgment performance were assessed in more than 90,000 women and 111,000 men from 53 nations. In all nations, men's mean performance exceeded women's on these two visuospatial tasks...
  22. pmc Learning a visuomotor rotation: simultaneous visual and proprioceptive information is crucial for visuomotor remapping
    Britne A Shabbott
    The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA
    Exp Brain Res 203:75-87. 2010
    ..Subjects were exposed to a visuomotor rotation, during which they received continuous visual feedback (CF) of hand position with instructions to correct or not ..
  23. pmc Multiple motor learning strategies in visuomotor rotation
    Naoki Saijo
    NTT Communication Science Laboratories, Nippon Telegraph and Telephone Corporation, Atsugi, Kanagawa, Japan
    PLoS ONE 5:e9399. 2010
    ..a continuous directional discrepancy between movements of a visible hand cursor and the actual hand (visuomotor rotation), subjects adapt their reaching movements so that the cursor is brought to the target...
  24. ncbi Intraoperative, full-rotation, three-dimensional image (O-arm)-based navigation system for cervical pedicle screw insertion
    Yoshimoto Ishikawa
    Department of Orthopedic Surgery, Spine Center, Konan Kosei Hospital, Takaya Chou, Konan City, Japan
    J Neurosurg Spine 15:472-8. 2011
    ..retrospectively evaluate the reliability and accuracy of cervical pedicle screw (CPS) placement using an intraoperative, full-rotation, 3D image (O-arm)-based navigation system and to assess the advantages and disadvantages of the system.
  25. ncbi F1-ATPase is a highly efficient molecular motor that rotates with discrete 120 degree steps
    R Yasuda
    Department of Physics, Faculty of Science and Technology, Keio University, Yokohama, Japan
    Cell 93:1117-24. 1998
    ..The work done in each step is constant over a broad range of imposed load and is close to the free energy of hydrolysis of one ATP molecule...
  26. ncbi Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain
    T Moriki
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Mol Biol 311:1011-26. 2001
    ..Kinetic analyses of the disulphide bonding indicate that EGF binding induces flexible rotation or twist of the juxtamembrane region of the receptor in the plane parallel with the lipid bilayer...
  27. ncbi Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis
    Michaela Brosig
    Friedrich Miescher Institute for Biomedical Research, Novartis Research Foundation, Basel, Switzerland
    Int J Biochem Cell Biol 42:1717-28. 2010
    ..Fibroblasts grown on flexible silicone membranes reacted to cyclic stretch by nuclear rotation. This rotation was abolished by inhibition of actomyosin contraction as well as by overexpression of dominant-..
  28. ncbi Sex differences and correlations in a virtual Morris water task, a virtual radial arm maze, and mental rotation
    Robert S Astur
    Department of Diagnostic Radiology, Yale University, New Haven, CT 06520, USA
    Behav Brain Res 151:103-15. 2004
    ..One of these tasks, the Vanderberg 3D mental rotation task, is classically used to assess spatial memory in humans...
  29. ncbi Vestibular thresholds for yaw rotation about an earth-vertical axis as a function of frequency
    Luzia Grabherr
    Department of Psychology, University of Lausanne, Bâtiment Anthropole, 1015 Lausanne, Switzerland
    Exp Brain Res 186:677-81. 2008
    Perceptual direction detection thresholds for yaw rotation about an earth-vertical axis were measured at seven frequencies (0.05, 0.1, 0.2, 0.5, 1, 2, and 5 Hz) in seven subjects in the dark...
  30. ncbi Visuo-spatial processing in autism--testing the predictions of extreme male brain theory
    Christine M Falter
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    J Autism Dev Disord 38:507-15. 2008
    ..While the group with ASD outperformed the control group at Mental Rotation and Figure-Disembedding, these group differences were not related to differences in prenatal testosterone level...
  31. ncbi Rotated alphanumeric characters do not automatically activate frontoparietal areas subserving mental rotation
    Michael M Weiss
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Neuroimage 44:1063-73. 2009
    ..the intraparietal sulcus and dorsal precentral cortex which show a linear increase in activity with the angle of rotation across a variety of mental rotation tasks...
  32. ncbi Feasibility and reproducibility of left ventricular rotation parameters measured by speckle tracking echocardiography
    Bas M van Dalen
    Department of Cardiology, The Thoraxcenter, Erasmus University Medical Center, s Gravendijkwal 230 Room BA 302, 3015 CE Rotterdam, The Netherlands
    Eur J Echocardiogr 10:669-76. 2009
    This study sought to find the most robust method for left ventricular (LV) rotation measurement by speckle tracking echocardiography (STE) with the new QLAB Advanced Quantification Software (version 6.0, Philips, Best, The Netherlands).
  33. ncbi EMG activity of trunk muscles and torque output during isometric axial rotation exertion: a comparison between back pain patients and matched controls
    Joseph K F Ng
    Department of Physiotherapy, The University of Queensland, Australia
    J Orthop Res 20:112-21. 2002
    ..EMG) activity of abdominal and back muscles as well as triaxial torque output during isometric axial rotation at different exertion levels in back pain patients and matched controls...
  34. pmc Eye orientation during static tilts and its relationship to spontaneous head pitch in the laboratory mouse
    Brian S Oommen
    Case Western Reserve University School of Medicine, Cleveland, OH 44106 5040, USA
    Brain Res 1193:57-66. 2008
    ..The robust tiltMOR also has significant methodological implications for the practice of pupil-tracking video oculography in this species...
  35. ncbi Evidence for interacting cortical control of vestibular function and spatial representation in man
    J Ventre-Dominey
    INSERM and CNRS Cognitive Sciences Institute UMR 5015, 67 Bd Pinel, 69500, Bron, France
    Neuropsychologia 41:1884-98. 2003
    ..reflex (VOR) was tested in complete darkness by rotating the subject around the vertical axis by sinusoidal rotation at different frequencies, and by steps of acceleration or deceleration...
  36. ncbi Influence of the pattern of hypertrophy on left ventricular twist in hypertrophic cardiomyopathy
    B M Van Dalen
    Department of Cardiology, The Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands
    Heart 95:657-61. 2009
    ..The influence of the pattern of LV hypertrophy on LV twist in hypertrophic cardiomyopathy (HCM) patients is unknown. This study sought to assess LV twist in a large group of HCM patients according to the pattern of LV hypertrophy...
  37. ncbi Functional MRI in healthy subjects during acupuncture: different effects of needle rotation in real and false acupoints
    J L Fang
    Department of Radiology, Guang An Men Hospital, China Academy of Traditional Chinese Medicine, Bei Xian Ge 5, 100053 Peking, China
    Neuroradiology 46:359-62. 2004
    ..These specific cerebral activation patterns might explain the therapeutic effects of acupuncture in certain subjects...
  38. ncbi Suitable stimuli to obtain (no) gender differences in the speed of cognitive processes involved in mental rotation
    Petra Jansen-Osmann
    Institute of Experimental Psychology, Heinrich Heine University, 40225 Dusseldorf, Germany
    Brain Cogn 64:217-27. 2007
    Gender differences in speed of perceptual comparison, of picture-plane mental rotation, and in switching costs between trials that do and do not require mental rotation, were investigated as a function of stimulus material with a total ..
  39. ncbi Sex differences in mental rotation: top-down versus bottom-up processing
    Tracy Butler
    Functional Neuroimaging Laboratory, Department of Psychiatry, Weill Medical College of Cornell University, Box 140, 1300 York Avenue, New York, NY 10021, USA
    Neuroimage 32:445-56. 2006
    Functional MRI during performance of a validated mental rotation task was used to assess a neurobiological basis for sex differences in visuospatial processing...
  40. pmc The rotation-coupled sliding of EcoRV
    Jasmina Dikic
    Laboratoire Kastler Brossel, ENS, UPMC Paris6, CNRS UMR 8552, 24 rue Lhomond, 75005 Paris, France
    Nucleic Acids Res 40:4064-70. 2012
    ..restriction enzymes (REs), such as EcoRV, track the helical pitch of DNA as they diffuse along DNA, a so-called rotation-coupled sliding...
  41. pmc Brain injury prediction: assessing the combined probability of concussion using linear and rotational head acceleration
    Steven Rowson
    Center for Injury Biomechanics, Virginia Tech Wake Forest, 440 ICTAS Building, Stanger St, Blacksburg, VA 24061, USA
    Ann Biomed Eng 41:873-82. 2013
    ..In the NFL dataset, there were no significant differences between parameters. The combined probability of concussion is a valuable method to assess concussion risk in a laboratory setting for evaluating product safety...
  42. ncbi Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome
    Istvan Albert
    Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Nature 446:572-6. 2007
    ..Transcriptional start sites tended to reside about one helical turn inside the nucleosome border. These findings reveal an intimate relationship between chromatin architecture and the underlying DNA sequence it regulates...
  43. pmc Self-rotation of cells in an irrotational AC E-field in an opto-electrokinetics chip
    Long Ho Chau
    Centre for Micro and Nano Systems, The Chinese University of Hong Kong, Hong Kong
    PLoS ONE 8:e51577. 2013
    ..among all the cells investigated, melan-a cells, lymphocytes and white blood cells were found to undergo self-rotation in the device in the presence of a DEP force...
  44. ncbi The effect of ankle rotation on cutting of the tibia in total knee arthroplasty
    Hideki Mizu-uchi
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3 1 1, Maidashi, Higashi ku, Fukuoka City, 812 8582, Japan
    J Bone Joint Surg Am 88:2632-6. 2006
    ..We hypothesized that a rotational mismatch might cause incorrect positioning of an extramedullary alignment guide and evaluated such a mismatch on the predicted postoperative coronal alignment of the tibia...
  45. ncbi Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures
    Satoshi Arai
    Department of Chemistry, Graduate School of Science, Chiba University, 1 33 Yayoi cho, Inage, Chiba 263 8522, Japan
    Nature 493:703-7. 2013
    ..To our knowledge, these asymmetric structures represent the first high-resolution view of the rotational mechanism of V(1)-ATPase...
  46. ncbi Vestibular perceptual thresholds to angular rotation in acute unilateral vestibular paresis and with galvanic stimulation
    Nicholas J Cutfield
    Neuro Otology Unit, Imperial College London, Charing Cross Hospital, London, United Kingdom
    Ann N Y Acad Sci 1233:256-62. 2011
  47. ncbi A novel effector secretion mechanism based on proton-motive force-dependent type III secretion apparatus rotation
    Takashi Ohgita
    Department of Biophysical Chemistry, Kyoto Pharmaceutical University, Misasagi Nakauchicho 5, Yamashina ku, Kyoto 607 8414, Japan
    FASEB J 27:2862-72. 2013
    ..In addition, both T3SA-dependent effector secretion and flagellar rotation were reported to require proton-motive force (PMF) for activity...
  48. pmc A kinesin motor in a force-producing conformation
    Elisabeth Heuston
    Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA
    BMC Struct Biol 10:19. 2010
    ..Perturbing the motor by introducing point mutations could stabilize transitional or unstable states, providing critical information about these rarer states...
  49. ncbi The influence of muscle load on tibiofemoral knee kinematics
    Jan Victor
    Department of Orthopaedics, AZ St Lucas, St Lucaslaan 29, 8310 Brugge, Belgium
    J Orthop Res 28:419-28. 2010
    ..of the medial (MFT) and lateral femoral condyles (LFT) in the horizontal plane of the tibia, and tibial axial rotation (TR) as a function of flexion angle...
  50. ncbi Sex differences of event-related potential effects during three-dimensional mental rotation
    Qingbao Yu
    Institute of Neuroinformatics, Dalian University of Technology, Dalian, China
    Neuroreport 20:43-7. 2009
    Sex differences in performance and in cortical activation patterns during mental rotation have rather consistently been reported...
  51. pmc Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd
    Mikyung Yun
    Department of Structural Biology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    EMBO J 22:5382-9. 2003
    ..motor core residues, observed in the head that moves with the stalk, are disrupted in the other head, permitting rotation of the stalk/neck. The rotation could represent a force-producing stroke that directs the motor to the minus end.
  52. ncbi Transcranial magnetic stimulation of primary motor cortex affects mental rotation
    G Ganis
    Department of Psychology, Harvard University and Laboratory for Magnetic Brain Stimulation, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Cereb Cortex 10:175-80. 2000
    ..overt motor behavior but also during tasks that require no overt motor behavior, such as motor imagery and mental rotation. We tested the hypothesis that activation of the primary motor cortex is needed for mental rotation by using ..
  53. ncbi Anticipating intentional actions: the effect of eye gaze direction on the judgment of head rotation
    Matthew Hudson
    School of Psychology, Bangor University, Adeilad Brigantia, Penrallt Road, Bangor, United Kingdom
    Cognition 112:423-34. 2009
    ..The gaze direction of the face was either congruent with, ahead of, or lagging behind the angle of rotation. Following this, two static faces, at varying angles of rotation with respect to the end-point angle of the face ..
  54. ncbi Magnetic resonance tissue phase mapping of myocardial motion: new insight in age and gender
    Daniela Föll
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstrasse 55, Freiburg, Germany
    Circ Cardiovasc Imaging 3:54-64. 2010
    ..Magnetic resonance phase-contrast imaging (tissue phase mapping) enabling the analysis of segmental, 3-directional myocardial velocities with high temporal resolution (13.8 ms) was used to assess left ventricular motion...
  55. ncbi Mental rotation meets the motion aftereffect: the role of hV5/MT+ in visual mental imagery
    Ruth Seurinck
    Department of Experimental Psychology, Ghent, Belgium
    J Cogn Neurosci 23:1395-404. 2011
    ..We induced a direction-selective adaptation in hV5/MT+ by means of an MAE while subjects performed a mental rotation task that elicits imagined motion...
  56. ncbi Computer-assisted knee arthroplasty versus a conventional jig-based technique. A randomised, prospective trial
    S K Chauhan
    Royal Perth Hospital, Perth, Western Australia
    J Bone Joint Surg Br 86:372-7. 2004
    ..032), femoral rotation (p = 0.001), tibial varus/valgus (p = 0.047) tibial posterior slope (p = 0.0001), tibial rotation (p = 0...
  57. ncbi Mechanisms of anterior cruciate ligament injury in World Cup alpine skiing: a systematic video analysis of 20 cases
    Tone Bere
    Oslo Sports Trauma Research Center, Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway
    Am J Sports Med 39:1421-9. 2011
    ..There is limited insight into the mechanisms of anterior cruciate ligament injuries in alpine skiing, particularly among professional ski racers...
  58. ncbi High-speed atomic force microscopy reveals rotary catalysis of rotorless F₁-ATPase
    Takayuki Uchihashi
    Department of Physics, Kanazawa University, Kakuma machi, Kanazawa 920 1192, Japan
    Science 333:755-8. 2011 has been done, the structural basis of cooperative torque generation to realize the unidirectional rotation remains elusive...
  59. pmc Precision and accuracy of the subjective haptic vertical in the roll plane
    Jeanine R Schuler
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    BMC Neurosci 11:83. 2010
    ..Twelve healthy right-handed human subjects (handedness assessed based on subjects' verbal report) adjusted a rod with the right hand along perceived earth-vertical during static head roll-tilts (0-360 degrees , steps of 20 degrees )...
  60. ncbi Assessment of subendocardial vs. subepicardial left ventricular rotation and twist using two-dimensional speckle tracking echocardiography: comparison with tagged cardiac magnetic resonance
    Céline Goffinet
    Division of Cardiology, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Brussels, Belgium
    Eur Heart J 30:608-17. 2009
  61. ncbi Whole-somite rotation generates muscle progenitor cell compartments in the developing zebrafish embryo
    Georgina E Hollway
    The Victor Chang Cardiac Research Institute, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia
    Dev Cell 12:207-19. 2007
    ..We also show that formation of this compartment occurs via whole-somite rotation, a process that requires the action of the Sdf family of secreted cytokines.
  62. pmc Interdependence of behavioural variability and response to small stimuli in bacteria
    Heungwon Park
    The James Franck Institute, The Institute for Biophysical Dynamics, and the Department of Physics, University of Chicago, Chicago, Illinois 60637, USA
    Nature 468:819-23. 2010
  63. ncbi Wing rotation and the aerodynamic basis of insect flight
    M H Dickinson
    Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    Science 284:1954-60. 1999
    ..A comprehensive theory incorporating both translational and rotational mechanisms may explain the diverse patterns of wing motion displayed by different species of insects...
  64. ncbi Imagining rotation by endogenous versus exogenous forces: distinct neural mechanisms
    S M Kosslyn
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Neuroreport 12:2519-25. 2001
    ..Following this, they performed the identical mental rotation task in which they compared members of pairs of such figures, but were asked to imagine the figures rotating as ..
  65. ncbi Using sensory weighting to model the influence of canal, otolith and visual cues on spatial orientation and eye movements
    L H Zupan
    Massachusetts Eye and Ear Infirmary, Department of Otology and Laryngology, Harvard Medical School, Boston 02114, USA
    Biol Cybern 86:209-30. 2002
    ..g., semicircular canals and vision both measure self-rotation)...
  66. ncbi Vestibular signals in primate thalamus: properties and origins
    Hui Meng
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 27:13590-602. 2007
    ..Few cells responded to rotation alone, with most showing convergence between semicircular canal and otolith signals...
  67. pmc Viscoelastic dynamics of actin filaments coupled to rotary F-ATPase: angular torque profile of the enzyme
    O Panke
    Division of Biophysics, University of Osnabruck, D 49069 Osnabruck, Germany
    Biophys J 81:1220-33. 2001
    ..It is considered as essential, not only for the robust operation of this ubiquitous enzyme under symmetry mismatch, but also for a high turnover rate of the two counteracting and stepping motor/generators...
  68. ncbi Spaceflight and clinorotation cause cytoskeleton and mitochondria changes and increases in apoptosis in cultured cells
    H Schatten
    Department of Veterinary Pathobiology, University of Missouri-Columbia, Columbia, MO 65211, USA
    Acta Astronaut 49:399-418. 2001
    ..and in insect cells of Drosophila melanogaster (Schneider S-1) after exposure to conditions created by clinostat rotation. Jurkat cells were flown on the space shuttle in Biorack cassettes while Schneider S-1 cells were exposed to ..
  69. ncbi Structure of bovine mitochondrial F(1)-ATPase with nucleotide bound to all three catalytic sites: implications for the mechanism of rotary catalysis
    R I Menz
    Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
    Cell 106:331-41. 2001
    ..A catalytic scheme for hydrolysis (and synthesis) at physiological rates and a mechanism for the ATP-driven rotation of the gamma subunit are proposed based on the crystal structures of the bovine enzyme.
  70. ncbi Early transplantation of an encapsulated glial cell line-derived neurotrophic factor-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease
    Takao Yasuhara
    Department of Neurological Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    J Neurosurg 102:80-9. 2005
    ..The authors investigated the effects of GDNF on 6-hydroxydopamine (6-OHDA)-treated dopaminergic neurons in vitro and in vivo...
  71. ncbi Effects of altered gravity on the actin and microtubule cytoskeleton of human SH-SY5Y neuroblastoma cells
    H Rosner
    Cell and Developmental Neurobiology, Institute of Zoology, University of Hohenheim, Stuttgart, Federal Republic of Germany
    Protoplasma 229:225-34. 2006
    ..The latter, however, seems to be promoted at hypergravity...
  72. ncbi Biomolecular reactions studied using changes in Brownian rotation dynamics of magnetic particles
    Andrea Prieto Astalan
    IMEGO AB, Arvid Hedvalls Backe 4, SE 411 33 Göteborg, Sweden
    Biosens Bioelectron 19:945-51. 2004
    ..Our method allows to perform an immunoassay in a single step and is much faster and cheaper compared to conventional ELISA procedures...
  73. ncbi Comparative study of trochanteric fracture treated with the proximal femoral nail anti-rotation and the third generation of gamma nail
    Xu Yaozeng
    Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, Jiangsu 215006, China
    Injury 41:1234-8. 2010
    To compare the results between the proximal femoral nail anti-rotation (PFNA) and the third generation gamma nail (TGN) in the treatment of trochanteric fractures.
  74. ncbi Mental-rotation deficits following damage to the right basal ganglia
    Irina M Harris
    Department of Medicine, University of Sydney, Australia
    Neuropsychology 16:524-37. 2002
    The authors report the case of a woman with a right basal ganglia lesion and severe mental-rotation impairments...
  75. ncbi Influence of a follower load on intradiscal pressure and intersegmental rotation of the lumbar spine
    A Rohlmann
    Biomechanics Laboratory, Orthopaedic Hospital of the Free University of Berlin, Germany
    Spine (Phila Pa 1976) 26:E557-61. 2001
    STUDY DESIGN: Intradiscal pressure and intersegmental rotation of human lumbar spines were measured in vitro. OBJECTIVES: To determine the effect of a follower load on mechanical behavior at all levels of the lumbar spine...
  76. ncbi Concurrent adaptations of left and right arms to opposite visual distortions
    Otmar Bock
    Institute of Physiology and Anatomy, German Sport University, 50927 Koln, Germany
    Exp Brain Res 162:513-9. 2005
    ..The reduced aftereffects observed under bimanual conditions can be attributed to the well-known phenomenon of bimanual coupling, which is unrelated to adaptation...
  77. ncbi Mesoscopic spatial designs of nano- and microfiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques
    Satoru Kidoaki
    Division of Biomedical Engineering, Graduate School of Medicine, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka City, Fukuoka 812 8582, Japan
    Biomaterials 26:37-46. 2005
    ..composed of SPU and PEO was prepared by simultaneous electrospinning on a stainless-steel mandrel with high-speed rotation and traverse movement...
  78. ncbi Motor processes in mental rotation
    M Wexler
    Laboratoire de la Physiologie de la Perception et de l Action, CNRS College de France, Paris, France
    Cognition 68:77-94. 1998
    ..For example, rotation may be guided by processes that also prime one to see results of a specific motor action...
  79. ncbi Dissociation between the mental rotation of visual images and motor images in unilateral brain-damaged patients
    Barbara Tomasino
    Programme in Neuroscience, Cognitive Neuroscience Sector, International School for Advanced Studies SISSA ISAS, Via Beirut 2 4, Trieste 34014, Italy
    Brain Cogn 51:368-71. 2003
    Deficits in the mental rotation of body parts and of external objects can be doubly dissociated (Rumiati, Tomasino, Vorano, Umiltà, & De Luce, 2001; Sirigu & Duhamel, 2001; Tomasino, Rumiati, & Umità, in press)...
  80. pmc Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching
    Lawrence K Lee
    Structural and Computational Biology Division, The Victor Chang Cardiac Research Institute, Lowy Packer Building, 405 Liverpool Street, Darlinghurst, New South Wales 2010, Australia
    Nature 466:996-1000. 2010
    The flagellar motor drives the rotation of flagellar filaments at hundreds of revolutions per second, efficiently propelling bacteria through viscous media...
  81. ncbi Implicit transfer of motor strategies in mental rotation
    Maryjane Wraga
    Department of Psychology, Smith College, Northampton, MA 01063, USA
    Brain Cogn 52:135-43. 2003
    Recent research indicates that motor areas are activated in some types of mental rotation. Many of these studies have required participants to perform egocentric transformations of body parts or whole bodies; however, motor activation ..
  82. ncbi Adaptation to visuomotor transformations: consolidation, interference, and forgetting
    John W Krakauer
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York 10032 2603, USA
    J Neurosci 25:473-8. 2005
    ..We have shown previously that adaptation to a 30 degrees screen-cursor rotation is faster and more complete on relearning 24 hr later...
  83. ncbi The influence of hands posture on mental rotation of hands and feet
    Silvio Ionta
    Department of Clinical Sciences and Bioimaging, Institute of Advanced Biomedical Technologies, University of Chieti Pescara G D Annunzio, Via dei Vestini 33, 66013, Chieti Scalo, Italy
    Exp Brain Res 183:1-7. 2007
    Behavioural and functional neuroanatomy studies demonstrate that mental rotation of body parts is carried out through a sort of inner motor simulation...
  84. ncbi Tilt and rotation correction of acetabular version on pelvic radiographs
    M Tannast
    Department of Orthopaedic Surgery, Inselspital, University of Bern, Bern, Switzerland
    Clin Orthop Relat Res 438:182-90. 2005
    ..The vertical and horizontal distances between two easy identifiable points were used as indicators of tilt and rotation. These points were the middle of the sacrococcygeal joint and the middle of the upper border of the symphyseal ..
  85. pmc ATP-driven stepwise rotation of FoF1-ATP synthase
    Hiroshi Ueno
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Yokohama 226 8503, Japan
    Proc Natl Acad Sci U S A 102:1333-8. 2005
    ..F1, a water-soluble ATPase portion of FoF1, rotates by repeating ATP-waiting dwell, 80 degrees substep rotation, catalytic dwell, and 40 degrees -substep rotation...
  86. ncbi Direct vertebral rotation: a new technique of three-dimensional deformity correction with segmental pedicle screw fixation in adolescent idiopathic scoliosis
    Sang Min Lee
    Seoul Spine Institute, Inje University, Sanggye Paik Hospital, Seoul, Korea
    Spine (Phila Pa 1976) 29:343-9. 2004
    ..A prospective study...
  87. pmc Effect of intracellular pH on rotational speed of bacterial flagellar motors
    Tohru Minamino
    Protonic NanoMachine Project, ERATO, JST, Seika, Kyoto 619 0237, Japan
    J Bacteriol 185:1190-4. 2003
    ..Both the swimming speeds and rotation rates of tethered cells of Salmonella also decreased considerably when the external pH was shifted from pH 7...
  88. pmc Domain compliance and elastic power transmission in rotary F(O)F(1)-ATPase
    Hendrik Sielaff
    Department of Biophysics, University of Osnabruck, 49069 Osnabruck, Germany
    Proc Natl Acad Sci U S A 105:17760-5. 2008
    ..They served to probe first the functional rotation and, after formation of the given disulfide bridge, the stochastic rotational motion...
  89. ncbi Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation
    Kengo Adachi
    Department of Physics, Faculty of Science and Engineering, Waseda University, Shinjuku ku, Tokyo 169 8555, Japan
    Cell 130:309-21. 2007
    ..How the chemical reactions that occur in three catalytic sites are coupled to mechanical rotation is the central question...
  90. pmc Sex differences in parietal lobe morphology: relationship to mental rotation performance
    Tim Koscik
    University of Iowa Neuroscience Graduate Program Drive, Department of Neurology, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Brain Cogn 69:451-9. 2009
    ..The parietal lobe is thought to be involved in spatial ability, and particularly involved in mental rotation. The purpose of this study is to examine whether sex differences in parietal lobe structure are present, and if ..
  91. ncbi Effect of fiber diameter on spreading, proliferation, and differentiation of osteoblastic cells on electrospun poly(lactic acid) substrates
    Anand S Badami
    Department of Chemical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0211, USA
    Biomaterials 27:596-606. 2006
    ..These studies show that topographical factors designed into biomaterial scaffolds can regulate spreading, orientation, and proliferation of osteoblastic cells...
  92. pmc Mechanochemical analysis of DNA gyrase using rotor bead tracking
    Jeff Gore
    Department of Physics, University of California, Berkeley, California 94720, USA
    Nature 439:100-4. 2006
    ..Here we observe the activity of gyrase in real time by tracking the rotation of a submicrometre bead attached to the side of a stretched DNA molecule...
  93. ncbi Women and men exhibit different cortical activation patterns during mental rotation tasks
    Kirsten Jordan
    Institute of Experimental and General Psychology, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Neuropsychologia 40:2397-408. 2002
    The strongest sex differences on any cognitive task, favoring men, are found for tasks that require the mental rotation of three-dimensional objects...
  94. ncbi Encoding of naturalistic optic flow by a population of blowfly motion-sensitive neurons
    K Karmeier
    Department of Neurobiology, Faculty for Biology, Bielefeld University, Bielefeld, Germany
    J Neurophysiol 96:1602-14. 2006
  95. ncbi Reduced self-motion perception in patients with midline cerebellar lesions
    Adolfo M Bronstein
    Division of Neuroscience and Mental Health, Imperial College London, UK
    Neuroreport 19:691-3. 2008
    ..functional MRI studies, however, show midline cerebellar activation during visually induced illusions of self-rotation, thus suggesting that the cerebellum may also contribute to self-motion perception...
  96. ncbi Selective impairment of hand mental rotation in patients with focal hand dystonia
    Mirta Fiorio
    Dipartimento di Scienze Neurologiche e della Visione, Sezione Fisiologia Umana, Universita degli Studi di Verona, Verona, Italy
    Brain 129:47-54. 2006
    Mental rotation of body parts determines activation of cortical and subcortical systems involved in motor planning and execution, such as motor and premotor areas and basal ganglia...
  97. ncbi Interpretation of a discontinuity in the sense of verticality at large body tilt
    Ronald G Kaptein
    Department of Biophysics, University of Nijmegen, 6525 EZ Nijmegen, The Netherlands
    J Neurophysiol 91:2205-14. 2004
    ..Beyond this range, both spatial-orientation tasks seem to rely mainly on a common tilt signal...
  98. ncbi A new model-based RSA method validated using CAD models and models from reversed engineering
    B L Kaptein
    Department of Orthopaedics, Leiden University Medical Center, P O Box 9600 RC, Leiden 2300, The Netherlands
    J Biomech 36:873-82. 2003
    ..whereby a 3D model of the implant is used for matching with the actual images and the assessment of position and rotation of the implant. In this study, a model-based RSA algorithm is presented and validated in phantom experiments...
  99. ncbi Preparatory activity in motor cortex reflects learning of local visuomotor skills
    Rony Paz
    Department of Physiology, Hadassah Medical School, The Hebrew University, Box 12272, Jerusalem 91120, Israel
    Nat Neurosci 6:882-90. 2003
    ..Here we replicated these behavioral findings in rhesus monkeys using a visuomotor rotation task and simultaneously recorded neuronal activity...
  100. pmc Mental rotation task of hands: differential influence number of rotational axes
    Arjan C ter Horst
    Donders Institute for Brain, Cognition and Behaviour, Centre for Cognition, Radboud University Nijmegen, Montessorilaan 3, P O Box 9104, 6500 HE, Nijmegen, The Netherlands
    Exp Brain Res 203:347-54. 2010
    ..e., lateral or medial rotation, respectively). These findings point to the use of a cognitive embodied process referred to as motor imagery...
  101. pmc Invariance to rotation in depth measured by masked repetition priming is dependent on prime duration
    Marianna D Eddy
    Tufts University, Medford, MA, USA
    Brain Res 1424:38-52. 2011
    ..We examined three ERP components, the P/N190, N300 and N400. In Experiment 1, only the 30° rotation condition produced repetition priming effects on the N/P190, N300 and N400...

Research Grants74

  1. Investigating Mechanism of Intracellular Rotational Transport with Optical T
    Jeffrey N Anker; Fiscal Year: 2012
    ..g. endoscopy). Results from a related technique pioneered by Dr. Miller (Co-I) demonstrate that intracellular rotation rate is a powerful indicator for macrophage health in vivo, and that rotatio is impaired by toxic nanoparticles ..
  2. Chronic Sleep Restriction Increases Immunity to Autoantigen: Role of the SNS
    Arnold E Postlethwaite; Fiscal Year: 2010
    ..Using this apparatus with a computer program to control disk rotation and produce chronic disrupted sleep, we have been studying the effect of chronic (14-30 day) sleep restriction on ..
  3. Development and Validation of an Instrument to Assess Cognitive Function Regulati
    Xi Chen; Fiscal Year: 2013
    ..and measurement design, epidemiology and statistics), clinical and research seminars, and supervised clinical rotation in the UNC neurology clinic. During this award Dr...
  4. Biophysics of the morphology and motility of Borrelia burgdorferi in diverse envi
    Charles W Wolgemuth; Fiscal Year: 2013
    ..The rotation of these periplasmic flagella against the cell wall leads to deformations of the cell cylinder, and these ..
  5. Effect of Helicobacter pylori cell shape on pathogenesis
    ..We will also directly probe the effect of cell shape on translational motion by measuring flagellar and cell body rotation for bacterial cell immobilized in gastric mucin gel at low pH (aim 1B)...
  6. Connective Tissue Mechanotransduction
    Helene M Langevin; Fiscal Year: 2012
    ..We also found that similar effects occur with acupuncture needle rotation due to winding and gathering of collagen around the rotating needle, essentially stretching the tissue "from the ..
  7. Visualizing Actomyosin Transients by Data Merging
    Thomas P Burghardt; Fiscal Year: 2013
    ..of the project is to elucidate the native relationships among actin binding, active site conformation, lever arm rotation and protein displacement and then to observe how these relationships are affected by modifications introduced to ..
  8. Development and Validation of a Diagnostic Tool for Infant Head Injuries from Fal
    SUSAN SHEPS contact MARGULIES; Fiscal Year: 2010
    ..subarachnoid hemorrhage) are determined by using a porcine computational model to simulate non-impact rapid head rotation experiments in 3-5 day old piglets...
  9. Development of high-throughput, commercially viable, Cell-CT instrument with init
    Thomas Neumann; Fiscal Year: 2010
    ..the Cell-CT creates hundreds of microscopic pseudo-projection images (with extended depth of focus) around 3600 rotation of each cell...
  10. Three-dimensional visualization, interactive analysis and contextual mapping of s
    PIERRE E GOOVAERTS; Fiscal Year: 2010
    ..g. using data query, feature highlights, 3D scene rotation) and 2) contextualize the results, such as cancer burden, through the use of background maps that incorporate ..
  11. Structure/Function of Complex II Oxidoreductase
    Gary Cecchini; Fiscal Year: 2012
    ..This interaction is important for controlling the direction of flagellar rotation and assembly...
  12. Sex-specific movement differences in young adults with and without hip pain
    CARA L LEWIS; Fiscal Year: 2013
    ..of the acetabulum or femur which results in early contact between the bones during hip flexion and internal rotation. Current treatment for FAI includes surgical procedures to resect or reorient the femur or acetabulum or both...
    ..GABA-A (aim 1a), GABA-B (aim 2b) and combined GABA-A and GABA-B (aim 1c) receptor antagonists during translation, rotation and their combinations...
  14. Biotechnology Training in Biomedical Sciences and Engineering
    Yi Tang; Fiscal Year: 2013
    ..curriculum composed of formal coursework in life science and engineering and of a cross-disciplinary laboratory rotation, and an industrial internship...
  15. Electrical Stimulation to Restore Three Dimensional Vestibular Sensation
    Charles C Della Santina; Fiscal Year: 2012
    ..Because the vestibular nerve should be intact in many of these patients, electrical stimuli encoding head rotation should be able to drive the nerve and restore sensation of head movement, much like a cochlear implant restores ..
  16. The Cellular Basis of Heterotopic Ossification
    David J Goldhamer; Fiscal Year: 2013
    ..inappropriate formation of bone in skeletal muscles and associated soft tissues, causes pain, swelling, decreased rotation of affected joints, and other health consequences...
  17. Fo Motor Mechanisms that Power FoF1 ATP Synthesis
    Wayne D Frasch; Fiscal Year: 2013
    ..The integral membrane Fo motor uses proton- motive force (PMF) to drive axle rotation for F1-dependent ATP synthesis...
  18. Cell Biology, Genetics, and Biochemistry Training Program
    DAVID OWEN MORGAN; Fiscal Year: 2013
    ..of active, excellent laboratories from which students can choose for their thesis research;(b) a laboratory rotation system that provides meaningful research experience in at least three different laboratories;(c) an excellent set ..
  19. Development of novel single-molecule approaches for nanoscale study of helicases
    Sanford H Leuba; Fiscal Year: 2010
    ..constrained DNA molecule induced by the immobilized helicase activity directly in the x- and y- plane as well as rotation of the DNA molecule in real time, and novel spFRET assays to understand the mechanism of action of a helicase...
  20. Sixth Annual OSSD Meeting
    Christine Carter; Fiscal Year: 2012
    ..were selected on the basis of scientific merit, relevance of the subject matter to the overall goals and rotation of topics of interest to both groups and inclusion of basic and clinical speakers...
  21. Planar Cell Polarity and the Cytoskeleton
    Andreas Jenny; Fiscal Year: 2013
    ..of the ommatidia in the eye, requiring highly coordinated movement of groups of photoreceptor cells (ommatidial rotation)...
    Barry L Taylor; Fiscal Year: 2011
    ..Reduction of FAD in the Aer PAS domain is proposed to cause a conformational change that induces rotation of a four-helix HAMP bundle, converting the Aer signal output from the kinase-off state to the kinase-on state...
  23. Training and research application for c-spine ultrasound of an aging population.
    DANIEL BUCKLAND; Fiscal Year: 2013
    ..will be followed by testing intact human cadavers subjected to dynamic flexion/extension, lateral tilt and axial rotation moments applied to the head and neck...
  24. Mechanobiology in CAM: Differential Effects of Amplitude
    ROBERT ALLEN HARTMAN; Fiscal Year: 2013
    ..Specifically, coupled axial rotation with posterior-anterior translation (simulating chiropractic mobilization loading patterns) and flexion- ..
  25. Hydrodynamic Chirality: A novel method for chiral separation and analysis
    Osman Kibar; Fiscal Year: 2013
    ..Due to their opposite handedness, they propel along the axis of field rotation in opposite directions, enabling both isolation and analysis, including absolute configuration determination...
  26. Training in the Molecular Basis of Skin/Mucosa Parthobiology
    Molly F Kulesz-Martin; Fiscal Year: 2013
    ..areas of epithelial carcinogenesis and inflammatory disease of surface epithelia (facilitated through monthly rotation of trainee presentations of data attended by all trainees and mentors, co-mentoring, and sharing specialized ..
  27. Intramolecular domain movements of PcrA during its helicase function
    Karen R Thickman; Fiscal Year: 2010
    ..conformational changes using spFRET and test the inchworm hypothesis of PcrA translocation, follow the mechanical rotation of the DMA labeled with a rotor bead as an immobilized PcrA molecule unwinds it;these rotations should correlate ..
  28. SARRP 200 Small animal radiation research platform
    Constantinos Koumenis; Fiscal Year: 2010
    ..The irradiation stage has 4-dimensional movement control (X-Y-Z and rotation) allowing complete flexibility of dose administration...
  29. Anterior Cruciate Ligament Reconstruction and the Initiation of Osteoarthritis
    Thomas P Andriacchi; Fiscal Year: 2013 our group, we can estimate the 6 degree-of-freedom motion of the tibiofemoral joint including internal tibial rotation and anterior tibial translation...
  30. Cannabinoid Receptor Interacting Protein1a Structure-Function
    ..Research findings from my first laboratory rotation indicated that CRIP1a over-expression in rat striatum is influenced by CB1 and D2 receptor levels, and CRIP1a ..
  31. Foot Progression Angle in Individuals with Diabetes &Peripheral Neuropathy
    ERICKA NAYRAM MERRIWETHER; Fiscal Year: 2013 to determine the contribution of foot progression angle (FPA), a spatial gait variable that represents foot rotation in the transverse plane, to the development of neuropathic plantar ulcers in adults with diabetes mellitus and ..
  32. Multi-faceted Approach to Modeling ACL Injury Mechanisms
    Timothy E Hewett; Fiscal Year: 2013
    ..findings show that combined knee abduction moment (KAM), anterior tibial shear force (ATS) and internal tibial rotation moment (ITR) generates significantly greater strain in the ACL relative to the MCL, and reproduces kinematics ..
    Howard C Berg; Fiscal Year: 2013
    ..Cells with flagella do this by controlling the direction of rotation of motors that drive helical propellers...
  34. Dental outcomes in Fibrous Dysplasia/McCune Albright Syndrome
    Sunday O Akintoye; Fiscal Year: 2013
    ..FD/MAS patients are also associated with dental disorders that include tooth rotation, tooth displacement, missing teeth, enamel hypoplasia, enamel hypomineralization, abnormally large pulp chamber, ..
  35. Annual meeting of the Organization for the Study of Sex Differences
    Kevin D Beck; Fiscal Year: 2013
    ..the basis of scientific merit, relevance to the goals of the OSSD, a balance of basic and clinical speakers, and rotation of topics of interest across annual meetings...
  36. Mechanisms underlying asymmetric rotation and vascular development of the midgut
    Natasza A Kurpios; Fiscal Year: 2013
    ..It has long been assumed that gut rotation is intrinsic to the tube itself;however, my research has demonstrated that rotation is instead determined by ..
  37. Origins of Renal Physiology
    Mark L Zeidel; Fiscal Year: 2011
    ..two-day rotations (Monday-Tuesday, Wednesday-Thursday, and Friday-Saturday), with the first day of each rotation involving intensive experimental work, and the second day involving analysis and presentation of the work to the ..
  38. Bridging multiple scales in modeling targeted drug nanocarrier delivery
    Ravi Radhakrishnan; Fiscal Year: 2013
    ..model will bridge multiple degrees of freedom at different length scales to incorporate: (i) NC translation and rotation as well as antigen/antibody translation, orientation and flexure~ (ii) effect of tethers mediating conformational ..
  39. Development of an anti-bias caster system
    TODD HARGRODER; Fiscal Year: 2010
    ..This is due location of the center of gravity (which is forward of the rear axle) and the unconstrained rotation of the caster wheels...
  40. Neurotrophin Drug Development for Parkinson's Disease
    William M Pardridge; Fiscal Year: 2012
    ..The drug efficacy in experimental PD will be validated with rotation behavior measurements, and assays of striatal tyrosine hydroxylase...
    RON M PRYWES; Fiscal Year: 2013
    ..This will be determined by their performance in the Core and other courses, recommendations from their rotation and thesis sponsors, and a short research proposal reviewed by the grant's steering committee...
    Grant T Gullberg; Fiscal Year: 2013
    ..kinetic model parameters, including the blood input function, directly from projections using slow camera rotation speeds without the need for arterial blood sampling. Misalignment between SPECT and CT will be corrected...
  43. Visual and Vestibular Percepts of Motion
    Benjamin T Crane; Fiscal Year: 2013
    ..The vestibular perception component will focus on determination of translation, heading perception, and rotation in normal controls and individuals with unilateral and bilateral peripheral vestibular lesions in the absence of ..
  44. Society for Developmental Biology Annual Meetings 2009-2013
    Marianne Bronner; Fiscal Year: 2013
    ..This meeting will be followed by gatherings in the Mountain region, Central region, and the East coast, as rotation throughout the various regions eases the travel burden for those with lower budgets...
  45. Cardiovascular Bioengineering Training Program
    Sanjeev G Shroff; Fiscal Year: 2013
    ..program is that students are required to formally participate in a clinical experience (Clinical Internship and Rotation)...
  46. Exposure Response Relationships for CTS and Epicondylitis from Pooled Data
    Arun Garg; Fiscal Year: 2013
    ..a wider range of biomechanical stressors: (i) with improved confidence and precision, (ii) for workers with job rotation, and (iii) for tasks with multiple combinations of force, repetition, and posture...
  47. Pathogenic Neisseria Meeting
    Caroline A Genco; Fiscal Year: 2010
    ..The sites have varied from within the Americas to other countries on a regular rotation, reflecting the international nature of the community of scientists that work on meningococcal and gonococcal ..
  48. Effect of femoroacetabular impingement (FAI) on hip motion in young adults
    CARA L LEWIS; Fiscal Year: 2013
    ..femur ("cam" FAI) which results in impingement between the acetabulum and femur during hip flexion and internal rotation. Current treatment for FAI includes surgical procedures to resect or reorient the femur or acetabulum or both...
  49. Laser spectroscopic instrumentation for isotopic sensing of biogenic Nitric Oxide
    Gerard Wysocki; Fiscal Year: 2012
    ..The new technology will be based on Faraday rotation spectroscopy, which can provide unprecedented sensitivity and specificity to NO...
  50. SMART Mounts: independent positioning of mounted devices by people with severe di
    DIANNE GOODWIN; Fiscal Year: 2011
    ..When preferred, rotation at the joints, tilt and height may be selectively adjusted with the chosen accessible controls...
  51. Translational Research Training Program in Environmental Health Sciences
    Trevor M Penning; Fiscal Year: 2013 and three rotations, one of which must be either a community-based research or population-based research rotation so that hands on training in environmental/molecular epidemiology is provided...
  52. Computer Simulation of Electron and Proton Transfer
    Arieh Warshel; Fiscal Year: 2013
    ..ii) Our recent breakthrough in modeling the conversion of pH gradients to vectorial rotation in the F0-ATPase will be quantified, striving to gain a better understanding of the proton paths...
  53. Structure-Function Relationships in the Spirochetal Flagellar Motor
    Jun Liu; Fiscal Year: 2013
    ..The coupling of an electrochemical gradient to mechanical rotation is one of the most fascinating features of this molecular machine...
  54. Local Sleep Regulation and Brain Plasticity
    Giulio Tononi; Fiscal Year: 2010
    ..We will use both an implicit learning task (rotation adaptation) involving right parietal cortex, and an explicit learning task involving prefrontal cortex (motor ..
    MICHAEL D FORGAC; Fiscal Year: 2013
    ..We have obtained evidence for helical swiveling (rotation of a helix about its long axis) in both subunit a and the proteolipid subunits...
  56. Orientation independent DIC and polarization microscopy
    Michael Shribak; Fiscal Year: 2011
    ..Extending the preliminary studies using conventional DIG coupled with specimen rotation, by which the theoretical validity of the proposed technique was validated, OI-DIC systems are proposed which ..
  57. Structures of Peptide Synthetases and Related Enzymes
    Andrew M Gulick; Fiscal Year: 2013
    ..A 140-degree domain rotation is hypothesized to allow the multiple states that direct the peptide to different catalytic domains in a ..
    Alan S Verkman; Fiscal Year: 2013
    ..SPT and quantum rod polarization correlation microscopy to investigate the determinants of AQP4 translational and rotation diffusion in live cells, and to study AQP diffusion in lamellipodia of migrating cells and the determinants of ..
  59. Personalized Motion Management for truly 4D Lung Stereotactic Body Radiotherapy
    Amit Sawant; Fiscal Year: 2013
    ..This technique will reshape the beam so as to follow all of the complex changes (translation, rotation and deformation) of the tumor and surrounding organs...
  60. Fifth Annual OSSD Meeting
    Amy B Wisniewski; Fiscal Year: 2011
    ..were selected on the basis of scientific merit, relevance of the subject matter to the overall goals and rotation of topics of interest to OSSD members, and inclusion of basic and clinical speakers...
    Reid C Johnson; Fiscal Year: 2013
    ..core of the Hin synaptic complex, provided strong evidence that recombination of DNA strands was mediated by rotation of Hin subunit pairs within the tetramer, and showed how the Fis/enhancer system together with DNA supercoiling ..
  62. Targeted Reinnervation and Pattern-Recognition Control for Transradial Amputees
    TODD ALAN KUIKEN; Fiscal Year: 2012
    ..will also develop new technologies to advance the control of prostheses that have more functions including wrist rotation, wrist flexion/extension and hands with moving fingers and thumbs...
  63. Molecular Modulation of Catalytic Sites of Escherichia coli F1Fo ATP Synthase
    Zulfiqar Ahmad; Fiscal Year: 2009
    ..Pi binding in the catalytic sites is linked to 3- subunit rotation. In order to understand the molecular function of this nanomotor, it is paramount to identify and characterize ..
  64. Automated Connective Tissue Torque Sensor
    Robert Davis; Fiscal Year: 2007
    ..combine technologies developed in our previous research and technological transfer programs which 1) showed that rotation of ultra-fine acupuncture needles causes winding of connective tissue measurable as increased needle torque and 2)..
    Andrew Norman; Fiscal Year: 1992
    ..The functional pharmacology will be investigated in rats with unilateral striatal KA lesions by assessing rotation behavior in response to apomorphine and D-amphetamine...
  66. Reducing Low-back Disorders Using a New Sitting Design
    Mohsen Makhsous; Fiscal Year: 2003
    ..Sitting may cause backward rotation of the pelvis, reduction in lumbar lordosis, changes in muscle activities and disc pressure, excessive pressure ..
    Richard Berger; Fiscal Year: 1999
    ..stabilizes the DRUJ against volar displacement of the radius relative to the ulna in all positions of forearm rotation; 1b) the dorsal radio-ulnar ligament stabilizes the DRUJ against lateral displacement of the radius relative to ..
  68. A Novel Implant-based Approach for Treating Retrognathic Hyperdivergent Patients
    Peter Buschang; Fiscal Year: 2007
    ..Our goal is to determine the feasibility of a novel treatment approach that relies on mandibular rotation to correct dysmorphology...
  69. Palliative Care Curriculum for Medical Residents
    Charles von Gunten; Fiscal Year: 2009
    ..In preliminary work, we have developed evaluation methods and curricula for physicians and established a hospice rotation for 65 residents training in three programs of internal medicine and two programs in family medicine each year...
  70. Medial Collapse Movement Impairments associated with Patellofemoral Pain
    GRETCHEN SALSICH; Fiscal Year: 2009
    ..Medial collapse has been described as a combination of excessive adduction and medial rotation of the femur, increased knee valgus, and increased lateral tibial rotation...
  71. Vibrotactile Feedback for Prosthetic Limbs II
    RONALD RISO; Fiscal Year: 2009
    ..of sensory information will be targeted for powered arms: grasp force, object slippage and either wrist rotation (i.e. pronation/supination) or span of finger opening...
  72. ActiveImplant Prosthesis for Lower Limb Amputees
    JOHN FAGO; Fiscal Year: 2007
    ..In order to improve distal weightbearing, reduce rotation of the socket around the residuum and improve clinical function for above-knee amputees, a new surgical method ..
  73. Proton-Translocating Sector of E. coli H+ATP Synthase
    Robert H Fillingame; Fiscal Year: 2010
    ..The H+-transporting F1Fo ATP synthases of oxidative phosphorylation in mitochondria and bacteria are very similar. Rotation of subunit 3 within the core of the ?3?3 hexamer of F1 drives ATP synthesis by a mechanically driven change in ..
    RICHARDUS ROSS; Fiscal Year: 2000
    ..and postmenopausal women, men and children to confirm their suitability of inclusion in a commercial soy-based rotation diet...