shear strength

Summary

Summary: The internal resistance of a material to moving some parts of it parallel to a fixed plane, in contrast to stretching (TENSILE STRENGTH) or compression (COMPRESSIVE STRENGTH). Ionic crystals are brittle because, when subjected to shear, ions of the same charge are brought next to each other, which causes repulsion.

Top Publications

  1. ncbi Wall shear stress--an important determinant of endothelial cell function and structure--in the arterial system in vivo. Discrepancies with theory
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, Maastricht, The Netherlands
    J Vasc Res 43:251-69. 2006
  2. ncbi Effect of blood contamination on shear bond strength of orthodontic brackets and disinclusion buttons
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, Pavia, Italy
    Br J Oral Maxillofac Surg 49:404-8. 2011
  3. pmc Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells
    Guadalupe Villarreal
    Laboratory for Systems Biology, Center for Excellence in Vascular Biology, Department of Pathology, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    Biochem Biophys Res Commun 391:984-9. 2010
  4. ncbi Effects of etchants and primers on shear bond strength of a self-ligating esthetic orthodontic bracket
    Robert Chalgren
    School of Dentistry, University of Minnesota, Minneapolis 55455, USA
    Am J Orthod Dentofacial Orthop 132:577.e1-5. 2007
  5. ncbi Plant extract ankaferd blood stopper effect on bond strength
    Goksu Trakyali
    Department of Orthodontics, Yeditepe University, Istanbul, Turkey
    Angle Orthod 80:570-4. 2010
  6. pmc Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress
    Stephen J White
    Bristol Heart Institute, University of Bristol Clinical Sciences South Bristol, Bristol, UK
    J Cell Physiol 226:2841-8. 2011
  7. ncbi Reconditioning of self-ligating brackets
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, Pavia, Italy
    Angle Orthod 82:158-64. 2012
  8. ncbi Fluid dynamics of heart development
    Arvind Santhanakrishnan
    Department of Biomedical Engineering, Georgia Institute of Technology, 315 Ferst Drive NW, Parker H Petit Biotechnology Building, Atlanta, GA 30332 0363, USA
    Cell Biochem Biophys 61:1-22. 2011
  9. pmc Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008
  10. ncbi Shear bond strength of deciduous and permanent bovine enamel
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, Italy
    J Adhes Dent 13:227-30. 2011

Research Grants

  1. FAILURE MECHANISMS OF REVISION JOINT REPLACEMENT
    Joan E Bechtold; Fiscal Year: 2013
  2. INTERLAKEN SERIES 3000 AXIAL-TORSIONAL MATERIALS TESTING
    Wilson Hayes; Fiscal Year: 1992
  3. FAILURE MECHANISMS OF REVISION JOINT REPLACEMENT
    Joan Bechtold; Fiscal Year: 2000
  4. LASER ACOUSTIC EVALUATION OF DENTAL MATERIALS BONDING
    EVAN GREENER; Fiscal Year: 1993
  5. S. aureus Enhances Interaction with Biomaterials
    Michael Hudson; Fiscal Year: 2004
  6. PMMA PRECOATED INTRAMEDULLARY IMPLANTS
    Joon Park; Fiscal Year: 1980
  7. INTERFACIAL PROPERTIES OF HAVERSIAN BONE
    LANNY GRIFFIN; Fiscal Year: 2002
  8. WALL SHEAR STRESS IN THE CARDIOVASCULAR SYSTEM
    JOHN TARBELL; Fiscal Year: 2003
  9. SHEAR STRESS EFFECTS ON ENDOTHELIAL TRANSPORT
    John M Tarbell; Fiscal Year: 2010
  10. CCNY/MSKCC BIOMEDICAL ENGINEERING PARTNERSHIP
    JOHN TARBELL; Fiscal Year: 2007

Detail Information

Publications276 found, 100 shown here

  1. ncbi Wall shear stress--an important determinant of endothelial cell function and structure--in the arterial system in vivo. Discrepancies with theory
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, Maastricht, The Netherlands
    J Vasc Res 43:251-69. 2006
    ..Applications of wall shear stress as in flow-mediated arterial dilation, clinically in use to assess endothelial cell (dys)function, are also addressed. This review starts with some background considerations and some theoretical aspects...
  2. ncbi Effect of blood contamination on shear bond strength of orthodontic brackets and disinclusion buttons
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, Pavia, Italy
    Br J Oral Maxillofac Surg 49:404-8. 2011
    ..001). Contamination of enamel by blood during bonding lowers the strength of the bond, more so with orthodontic brackets than with bondable buttons...
  3. pmc Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells
    Guadalupe Villarreal
    Laboratory for Systems Biology, Center for Excellence in Vascular Biology, Department of Pathology, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    Biochem Biophys Res Commun 391:984-9. 2010
    ..Collectively, our data identify a significant degree of mechanistic and functional conservation between KLF2 and KLF4, and importantly, provide further insights into the complex regulatory networks governing endothelial vasoprotection...
  4. ncbi Effects of etchants and primers on shear bond strength of a self-ligating esthetic orthodontic bracket
    Robert Chalgren
    School of Dentistry, University of Minnesota, Minneapolis 55455, USA
    Am J Orthod Dentofacial Orthop 132:577.e1-5. 2007
    ....
  5. ncbi Plant extract ankaferd blood stopper effect on bond strength
    Goksu Trakyali
    Department of Orthodontics, Yeditepe University, Istanbul, Turkey
    Angle Orthod 80:570-4. 2010
    ..To determine the effect of Ankaferd Blood Stopper (ABS) on the shear bond strength (SBS) of orthodontic attachments...
  6. pmc Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress
    Stephen J White
    Bristol Heart Institute, University of Bristol Clinical Sciences South Bristol, Bristol, UK
    J Cell Physiol 226:2841-8. 2011
    ..In summary, LSS75 induced a specific change in behavior, modifying gene expression, reducing ROS levels, altering MAP kinase signaling and reducing cAMP levels, opening multiple avenues for future study...
  7. ncbi Reconditioning of self-ligating brackets
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, Pavia, Italy
    Angle Orthod 82:158-64. 2012
    ..To test the null hypothesis that there is no significant difference in the shear bond strength (SBS) and Adhesive Remnant Index (ARI) scores of new vs reconditioned self-ligating brackets...
  8. ncbi Fluid dynamics of heart development
    Arvind Santhanakrishnan
    Department of Biomedical Engineering, Georgia Institute of Technology, 315 Ferst Drive NW, Parker H Petit Biotechnology Building, Atlanta, GA 30332 0363, USA
    Cell Biochem Biophys 61:1-22. 2011
    ..The relevant work in cardiac morphology, muscle mechanics, regulatory networks, and electrophysiology is also reviewed in the context of intracardial fluid dynamics...
  9. pmc Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008
    ..Low wall shear stress (WSS) has been reported to have a negative effect on endothelial cells normal physiology and may be an important contributor to local remodeling of the arterial wall and to aneurysm growth and rupture...
  10. ncbi Shear bond strength of deciduous and permanent bovine enamel
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, Italy
    J Adhes Dent 13:227-30. 2011
    ..The use of bovine teeth as a substitute for human enamel has been proposed for dental studies. The aim of this study was to determine the shear bond strength and Adhesive Remnant Index (ARI) of deciduous and permanent bovine teeth...
  11. ncbi Effects of extracellular fiber architecture on cell membrane shear stress in a 3D fibrous matrix
    John A Pedersen
    Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
    J Biomech 40:1484-92. 2007
    ....
  12. ncbi The forgotten face of regular physical exercise: a 'natural' anti-atherogenic activity
    Justyna Szostak
    Service de Medecine Vasculaire, Departement de Medecine Interne, Centre Hospitalier Universitaire Vaudois CHUV, 1011 Lausanne, Switzerland
    Clin Sci (Lond) 121:91-106. 2011
    ..The down-regulation of TNF-α induced by skeletal-muscle-derived IL-6 may also participate in mediating the atheroprotective effect of physical activity...
  13. ncbi Laser etching of enamel for direct bonding with an Er,Cr:YSGG hydrokinetic laser system
    Serdar Usumez
    Faculty of Dentistry, Department of Orthodontics, Selcuk University, Konya 42079, Turkey
    Am J Orthod Dentofacial Orthop 122:649-56. 2002
    ..Although laser devices are effectively used in some other areas of dentistry, enamel conditioning with an Er,Cr:YSGG laser cannot be considered a successful alternative to the conventional methods of increasing bond strengths to enamel...
  14. ncbi The role of shear stress in the pathogenesis of atherosclerosis
    Kristopher S Cunningham
    Department of Pathology, Toronto General Research Institute, University Health Network, Canada
    Lab Invest 85:9-23. 2005
    ..Thus, shear stress is critically important in regulating the atheroprotective, normal physiology as well as the pathobiology and dysfunction of the vessel wall through complex molecular mechanisms that promote atherogenesis...
  15. pmc Blood contamination effect on shear bond strength of an orthodontic hydrophilic resin
    Taís de Morais Alves da Cunha
    Dental School, Pontifical Catholic University of Parana, Curitiba, PR, Brazil
    J Appl Oral Sci 20:89-93. 2012
    ..The aim of this study was to assess the impact of blood contamination on shear bond strength (SBS) and bond failure pattern of metallic brackets bonded using a new hydrophilic resin...
  16. ncbi Enamel and dentin bond strength following gaseous ozone application
    Milena Cadenaro
    Department of Biomedicine, University of Trieste, Trieste, Italy
    J Adhes Dent 11:287-92. 2009
    ..To evaluate the effects of gaseous ozone application on enamel and dentin bond strength produced by two self-etching adhesive systems...
  17. ncbi Bond strengths of two adhesive systems to dentin contaminated with a hemostatic agent
    Watcharaporn Kuphasuk
    Department of Operative Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
    Oper Dent 32:399-405. 2007
    ..The bond strength of CB20 to contaminated dentin was significantly lower than that to normal dentin. The extension of primer application time from 20 to 40 seconds significantly increased the bond strength of CB to contaminated dentin...
  18. pmc Effects of disturbed flow on endothelial cells
    Shu Chien
    Department of Bioengineering, University of California, San Diego, PFBH room 134, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    Ann Biomed Eng 36:554-62. 2008
    ..Understanding of the EC responses to different flow patters helps to elucidate the mechanism of the region-specific localization of atherosclerosis in the arterial system...
  19. ncbi Shear bond strength of orthodontic resins after caries infiltrant preconditioning
    Ewelina Naidu
    Department of Preventive Dentistry, Periodontology and Cariology, University of Zurich, 8032 Zurich, Switzerland
    Angle Orthod 83:306-12. 2013
    ..To investigate the influence of caries infiltrant preconditioning on the shear bond strength of orthodontic resin cements on sound and demineralized enamel...
  20. ncbi Effect of blood contamination on the shear bond strength at resin/dentin interface in primary teeth
    Maria Stella Raffaini
    Department of Pediatric Clinics, Preventive and Social Dentistry, University of Sao Paulo, Ribeirao Preto, SP, Brazil
    Am J Dent 21:159-62. 2008
    ..To assess in vitro the shear bond strength at the resin/dentin interface in primary teeth after contamination with fresh human blood...
  21. ncbi A computational fluid dynamic study of stent graft remodeling after endovascular repair of thoracic aortic dissections
    Stephen W K Cheng
    Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    J Vasc Surg 48:303-9; discusion 309-10. 2008
    ..We used computational fluid dynamic techniques to analyze the biomechanical factors associated with stent graft remodeling in these patients...
  22. ncbi Influence of moisture conditions on dentin bond strength of single-step self-etch adhesive systems
    Yasushi Chiba
    Nihon University Graduate School of Dentistry, Tokyo, Japan
    J Oral Sci 48:131-7. 2006
    ..Failure after the test was commonly due to adhesive breakdown associated with partial cohesive failure in the dentin. These data suggest that air-drying of the dentin surface is appropriate for the adhesive systems tested...
  23. ncbi Effect of drying time of 3-methacryloxypropyltrimethoxysilane on the shear bond strength of a composite resin to silica-coated base/noble alloys
    Mutlu Ozcan
    Department of Dentistry and Dental Hygiene, Faculty of Medical Sciences, University of Groningen, Antonius Deusinglaan 1, NL 9713 AV, The Netherlands
    Dent Mater 20:586-90. 2004
    ....
  24. ncbi The effect of a 3-methacryloxypropyltrimethoxysilane and vinyltriisopropoxysilane blend and tris(3-trimethoxysilylpropyl)isocyanurate on the shear bond strength of composite resin to titanium metal
    Jukka P Matinlinna
    Department of Prosthetic Dentistry and Biomaterials Research, Institute of Dentistry, University of Turku, Lemminkaisenkatu 2, 20520, Finland
    Dent Mater 20:804-13. 2004
    ..The aim of this study was to evaluate the reactions of silanes prior to attaching the composite to titanium and evaluate these silanes as coupling agents. Veneered titanium may be used as a prosthetic material...
  25. ncbi Effect of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells
    Yan Huang
    Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Yue Yuan Road no 37, Beijing, China
    Arch Med Res 41:497-505. 2010
    ..We investigated whether fluid shear stress (FSS), which is a mechanical load generated by fluid flow, can regulate rat BMSC (rBMSC) differentiation into cardiomyocytes...
  26. ncbi Shear bond strength of self-ligating brackets
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, Italy
    Eur J Orthod 33:71-4. 2011
    ..Moreover, groups 1 and 3 showed a higher frequency of ARI score 1, whereas groups 2 and 4 showed higher frequency of ARI score 2. All the brackets demonstrated a clinically adequate SBS...
  27. ncbi Evaluation of five dental silanes on bonding a luting cement onto silica-coated titanium
    J P Matinlinna
    Department of Prosthetic Dentistry and Biomaterials Science, Institute of Dentistry, University of Turku, Lemminkaisenkatu 2, FI 20520 Turku, Finland
    J Dent 34:721-6. 2006
    ..Five commercial dental silanes were evaluated in vitro as adhesion promoters bonding a luting cement to silica-coated titanium surfaces...
  28. ncbi The effect of tooth bleaching on the shear bond strength of orthodontic brackets
    Samir E Bishara
    Orthodontic Department, College of Dentistry, University of Iowa, Iowa City, IA 52242 1001, USA
    Am J Orthod Dentofacial Orthop 128:755-60. 2005
    ..The purpose of this study was to determine the effect of enamel bleaching on the shear bond strength of orthodontic brackets bonded with a composite adhesive...
  29. ncbi Influence of light intensity on dentin bond strength of self-etch systems
    Akira Yamamoto
    Nihon University Graduate School of Dentistry, Tokyo, Japan
    J Oral Sci 48:21-6. 2006
    ..Further research will be required to clarify the irradiance-dependent properties of light-cured resin adhesive systems...
  30. ncbi Effect of air-drying time of single-application self-etch adhesives on dentin bond strength
    Yasushi Chiba
    Nihon University Graduate School of Dentistry, Department of Operative Dentistry, Tokyo, Japan
    Oper Dent 31:233-9. 2006
    ..For all five of the systems studied, a five-second air-drying time appeared to be appropriate...
  31. ncbi The influence of different bracket base surfaces on tensile and shear bond strength
    Tjalling J Algera
    Department of Orthodontics, Academic Centre for Dentistry Amsterdam, Universiteit van Amsterdam and Vrije Universiteit, The Netherlands
    Eur J Orthod 30:490-4. 2008
    ..Improvement of the bond between bracket and cement might be found in other variables of the bracket-cement-enamel system such as the elasticity of the materials...
  32. ncbi 3-D numerical simulation of blood flow through models of the human aorta
    L Morris
    Centre for Applied Biomedical Engineering Research, Dept Mechanical and Aeronautical Eng and Material and Surface Science Institute, University of Limerick, Castletroy, Limerick, Ireland
    J Biomech Eng 127:767-75. 2005
    ..Flow patterns obtained from transient 3-D computational fluid dynamics are influenced by different reconstruction methods and the pulsatility of the flow. Caution is required when analyzing models based on CT scans...
  33. ncbi Modulation of erythrocyte deformability by PKC activity
    Sofia de Oliveira
    Instituto de Bioquimica, Unidade Biologia Microvascular e Inflamacao, Instituto de Medicina Moecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
    Clin Hemorheol Microcirc 39:363-73. 2008
    ..Better understanding of those proteins interactions on transduction mechanisms might trigger possible targets for drug action that would modulate EEI...
  34. ncbi A decoupled fluid structure approach for estimating wall stress in abdominal aortic aneurysms
    Yannis Papaharilaou
    Institute of Applied and Computational Mathematics, Foundation for Research and Technology Hellas, P O Box 1385, 71110 Heraklion, Crete, Greece
    J Biomech 40:367-77. 2007
    ..5% compared to the proposed decoupled fluid structure approach. Furthermore, the decoupled approach provides potentially useful information on the nature of the aneurysmal sac flow...
  35. ncbi Shear bond strength comparison between two orthodontic adhesives and self-ligating and conventional brackets
    Rodney G Northrup
    Marquette University, Milwaukee, WI 53201 1881, USA
    Angle Orthod 77:701-6. 2007
    ..To evaluate and compare the shear bond strengths of two adhesives using two types of brackets: a conventional and a self-ligating bracket system...
  36. ncbi Shear versus micro-shear bond strength test: a finite element stress analysis
    Eliane Placido
    Department of Dental Materials, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil
    Dent Mater 23:1086-92. 2007
    ..This study aimed at comparing the stress distribution in shear and micro-shear test set-ups using finite element analysis, and suggesting some parameter standardization that might have important influence on the results...
  37. ncbi Dentin bond strength of composites with self-etching adhesives using LED curing lights
    Yonca Korkmaz
    Department of Conservative Dentistry, Faculty of Dentistry, Hacettepe University, Ankara, Turkey
    J Contemp Dent Pract 8:34-42. 2007
    ....
  38. pmc "Go with the flow": how Krüppel-like factor 2 regulates the vasoprotective effects of shear stress
    Lalitha Nayak
    Division of Hematology Oncology, Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Antioxid Redox Signal 15:1449-61. 2011
    ..This review summarizes the current understanding of Krüppel-like factor 2 action in endothelial gene expression and function...
  39. ncbi Effect of using self-etching primer for bonding orthodontic brackets
    Rieko Yamada
    Department of Orthodontics, Nihon University School of Dentistry at Matsudo, Chiba, Japan
    Angle Orthod 72:558-64. 2002
    ..Megabond self-etching primer may be a candidate for bonding orthodontic brackets using the resin-modified glass ionomer cement for minimizing the amount of enamel loss...
  40. pmc Anterior shear strength of the porcine lumbar spine after laminectomy and partial facetectomy
    Guido B van Solinge
    Department of Orthopedic Surgery, VU University Medical Center, Amsterdam, The Netherlands
    Eur Spine J 19:2130-6. 2010
    ..The effect of this procedure on the shear strength of the spine has not yet been investigated in vitro...
  41. ncbi An in vitro comparative assessment of different enamel contaminants during bracket bonding
    Andreas Faltermeier
    Department of Orthodontics, University Clinics, Regensburg, Germany
    Eur J Orthod 29:559-63. 2007
    ..Under dry conditions hydrophilic or hydrophobic primers could be applied. Blood contamination seems to be a more serious problem for bond strength than saliva or etching gel contamination...
  42. ncbi Influence of surface treatment and simulated aging on bond strengths of luting agents to zirconia
    Markus B Blatz
    Department of Preventive and Restorative Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia 19104, USA
    Quintessence Int 38:745-53. 2007
    ..To evaluate short- and long-term shear bond strengths of 4 luting agents to zirconia following different surface treatments...
  43. ncbi Wall shear stress on ruptured and unruptured intracranial aneurysms at the internal carotid artery
    L D Jou
    Department of Radiology, Baylor College of Medicine, Houston, TX 77030, USA
    AJNR Am J Neuroradiol 29:1761-7. 2008
    ..Flow impingement, greater pressure, and abnormal wall shear stress are all indications for aneurysm rupture. Characterizing wall shear stress for intracranial aneurysms at similar anatomic locations may help in understanding its role...
  44. ncbi Effect of blood and saliva contamination on bond strength of brackets bonded with a protective liquid polish and a light-cured adhesive
    Korkmaz Sayinsu
    Faculty of Dentistry, Yeditepe University, Istanbul, Turkey
    Am J Orthod Dentofacial Orthop 131:391-4. 2007
    ....
  45. ncbi Effects of silica coating and silane surface conditioning on the bond strength of metal and ceramic brackets to enamel
    Saadet Saglam Atsu
    Prosthetic Dentistry, Kirikkale University, Turkey
    Angle Orthod 76:857-62. 2006
    ..To evaluate the effect of tribochemical silica coating and silane surface conditioning on the bond strength of metal and ceramic brackets bonded to enamel surfaces with light-cured composite resin...
  46. ncbi Shear bond strength of bonding to enamel with different laser irradiation distances
    Guvenc Basaran
    Faculty of Dentistry, Department of Orthodontics, Dicle University, 21280, Diyarbakir, Turkey
    Lasers Med Sci 26:149-56. 2011
    ..The mean shear bond strengths and enamel surface etching obtained with the Er:YAG laser at 1 and 2 mm and the Er,Cr:YSGG laser at 1 mm were comparable to that obtained with acid etching...
  47. ncbi Light curing the primer-beneficial when working in problem areas?
    Korkmaz Sayinsu
    Department of Orthodontics, Yeditepe University, Istanbul, Turkey
    Angle Orthod 76:310-3. 2006
    ..To minimize the negative effect of contamination on bond strength, it would be appropriate for clinicians to light cure immediately after the application of the primer...
  48. ncbi Effects of blood contamination on the shear bond strengths of conventional and hydrophilic primers
    Vittorio Cacciafesta
    Department of Orthodontics, University of Insubria, Varese, Italy
    Am J Orthod Dentofacial Orthop 126:207-12. 2004
    ..Blood contamination of enamel during the bonding procedure of conventional and hydrophilic primers significantly lowers their bond strength values and might produce a bond strength that is not clinically adequate...
  49. ncbi Effect of blood and saliva contamination on shear bond strength of brackets bonded with 4 adhesives
    Mehmet Oguz Oztoprak
    Faculty of Dentistry, Yeditepe University, Istanbul, Turkey
    Am J Orthod Dentofacial Orthop 131:238-42. 2007
    ..The purpose of this study was to assess the effect of blood and saliva contamination on the shear bond strength of 4 orthodontic adhesives...
  50. ncbi Immediate repair bond strengths of microhybrid, nanohybrid and nanofilled composites after different surface treatments
    Margareta Rinastiti
    Department of Biomedical Engineering, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands
    J Dent 38:29-38. 2010
    ..To evaluate immediate repair bond strengths and failure types of resin composites with and without surface conditioning and characterize the interacting composite surfaces by their surface composition and roughness...
  51. ncbi Effect of different adhesive systems and laser treatment on the shear bond strength of bleached enamel
    Sevil Gurgan
    Hacettepe University, School of Dentistry, Department of Restorative Dentistry, Sihhiye 06100, Ankara, Turkey
    J Dent 37:527-34. 2009
    ..This study determined the shear bond strength of a nanohybrid composite resin to bleached enamel immediately or 15 days later using different adhesive systems and laser application...
  52. ncbi Effect of artificial saliva contamination on pH value change and dentin bond strength
    Noriko Hiraishi
    Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan
    Dent Mater 19:429-34. 2003
    ..This study was to examine the effect of artificial saliva contamination on pH change of the dentin surface and the micro-shear bond strength (MSBS) of the two bonding systems to contaminated dentin...
  53. ncbi Shear strength of core-veneer interface in bi-layered ceramics
    Hana M Al-Dohan
    School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA
    J Prosthet Dent 91:349-55. 2004
    ..Whether this phenomenon is an inherent weakness of the veneering porcelain due to a weak interface between the veneering and the core porcelains, or merely a fracture through the veneering porcelain itself, has not been explored...
  54. ncbi Adhesive bonding of Ti-6Al-7Nb alloy and component metals with acidic primers and a tri-n-butylborane initiated resin
    Hiroyasu Koizumi
    Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan
    J Adhes Dent 14:283-92. 2012
    ..To evaluate the effects of acidic functional monomers on the bond strength and durability of an acrylic resin joined to Ti-6Al-7Nb alloy and component metals...
  55. ncbi Composite resin to yttria stabilized tetragonal zirconia polycrystal bonding: comparison of repair methods
    Priscila Cristoforides
    Sao Paulo State University UNESP, Sao Jose dos Campos, Brazil
    Oper Dent 37:263-71. 2012
    ..The purpose of the current study was to evaluate different approaches for bonding composite to the surface of yttria stabilized tetragonal zirconia polycrystal (Y-TZP) ceramics...
  56. ncbi The effect of a novel silane blend system on resin bond strength to silica-coated Ti substrate
    J P Matinlinna
    NIOM Nordic Institute of Dental Materials, P O Box 70, NO 1305 Haslum, Norway
    J Dent 34:436-43. 2006
    ....
  57. ncbi Influence of Ankaferd Blood Stopper on shear bond strength of bonding systems
    Soley Arslan
    Department of Restorative Dentistry and Endodontics, Faculty of Dentistry, Erciyes University, Kayseri, Turkey
    Dent Mater J 31:226-31. 2012
    ..There were significant differences in bond strengths between the control and ABS-contaminated samples. These findings suggest that ABS contamination reduced bond strength of total- and self-etching adhesives...
  58. ncbi Influence of enamel wetness on composite restorations using various dentine bonding agents: part II-effects on shear bond strength
    Shu Fen Chuang
    Institute of Oral Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
    J Dent 34:352-61. 2006
    ..To investigate the bond strength and fracture characteristics of various dentine bonding agents (DBAs) on wet or dry enamel...
  59. ncbi Adhesive bonding of resin cements to cast titanium with adhesive primers
    Marina Di Francescantonio
    Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, SP, Brazil
    Braz Dent J 23:218-22. 2012
    ..Panavia F 2.0 and RelyX ARC yielded high bond strength means with or without adhesive primers. The use of adhesive primers might increase the bond strength to cast titanium depending on the resin cement used...
  60. pmc Three-dimensional phase contrast angiography of the mouse aortic arch using spiral MRI
    Robert L Janiczek
    Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA
    Magn Reson Med 66:1382-90. 2011
    ..14 ± 0.01 vs. 0.08 ± 0.01; P < 0.01). This finding is in agreement with humans, where WSS is lower and more oscillatory along the inner radius, an atheroprone region, than the outer radius, an atheroprotective region...
  61. ncbi Influence of microhybrid resin and etching times on bleached enamel for the bonding of ceramic brackets
    Leily Macedo Firoozmand
    Department of Dentistry, School of Dentistry, Univ CEUMA, Sao Luis, MA, Brazil
    Braz Oral Res 27:142-8. 2013
    ..The type of composite resin, etching time and external bleaching significantly influenced the SBS of PCB on enamel, even after 14 days of saliva storage...
  62. ncbi Comparative evaluation of shear bond strength of different bracket base designs in dry and wet environments
    O P Mehta
    Department of Orthodontics, MMCDSR, Mullana Ambala, India
    J Indian Soc Pedod Prev Dent 26:S104-8. 2008
    ..Conventional Transbond XT in dry conditions and M.I.P in dry and wet environments. The specimens were tested for SBS using Instron machine at C.I.P.E.T. (Amritsar), Punjab. Results were statistically analyzed...
  63. ncbi Effects of a convenient silica-coating treatment on shear bond strengths of porcelain veneers on zirconia-based ceramics
    Takuya Oguri
    Department of Oral Biomaterials and Technology, Showa University School of Dentistry, 1 5 8 Hatanodai, Shinagawa ku, Tokyo, Japan
    Dent Mater J 31:788-96. 2012
    ..05). However, differences among treated specimens were not significant. Moreover, SP gave superior wettability, and smoothness as good as NT. These data suggest that SP affects the bond strength between zirconia and a porcelain veneer...
  64. ncbi Effects of sol-gel processed silica coating on bond strength of resin cements to glass-infiltrated alumina ceramic
    Haifeng Xie
    Department of Prosthodontics, Stomatology Institute of Nanjing Medical University, Jiang Su Province, People s Republic of China
    J Adhes Dent 11:49-55. 2009
    ..The aim of this study was to verify the effects of sol-gel processed silica coating on the bond strength between resin cement and glass-infiltrated aluminum oxide ceramic...
  65. ncbi Bonding agent underneath sealant: shear bond strength to oil-contaminated
    Maria Cristina Borsatto
    Department of Pediatric Clinics, Preventive and Community Dentistry, Ribeirao Preto Dental School, University of Sao Paulo, Ribeirao Preto, SP, Brazil
    Braz Dent J 21:50-4. 2010
    ..91). It may be concluded that the oil contamination affected negatively the sealant bonding to enamel and the acetone-based adhesive system (PB) layer applied underneath the sealant was able to prevent its deleterious effects to adhesion...
  66. ncbi The effect of trichloracetic acid as a hemostatic and etching agent on the morphological characteristics and shear bond strength of resin composite to enamel
    Maryam Khoroushi
    Department of Operative Dentistry and Torabinejad Dental Research Center, Faculty of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
    Oper Dent 35:187-93. 2010
    ..This study evaluated the effect of TCA gel as an etchant, its use before etchant on the shear bond strength between resin composite and enamel and also its effect on enamel surface morphological characteristics...
  67. ncbi The role of etching in bonding to enamel: a comparison of self-etching and etch-and-rinse adhesive systems
    Robert L Erickson
    Department of General Dentistry, Creighton University School of Dentistry, 2500 California Plaza, Omaha, NE 68178, USA
    Dent Mater 25:1459-67. 2009
    ..The hypothesis was that similar morphology would result in similar bond strength assuming micro-mechanical bonding is the mechanism of adhesion...
  68. ncbi Bond strength of poly(methyl methacrylate) denture base material to cast titanium and cobalt-chromium alloy
    Yasuhiro Matsuda
    Department of Applied Prosthodontics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    J Adhes Dent 12:223-9. 2010
    ..The shear bond strength of an auto-polymerizing poly(methyl methacrylate) denture base resin material to cast titanium and cobalt-chromium alloy treated with six conditioning methods was investigated...
  69. ncbi Effect of primer precuring on the shear bond strength of orthodontic brackets
    Larry J Oesterle
    Department of Orthodontics, University of Colorado School of Dentistry, Denver, CO 80262, USA
    Am J Orthod Dentofacial Orthop 126:699-702. 2004
    ..There is no advantage or disadvantage in bracket bond strength by precuring the primer before placing the bracket and filled component of the adhesive...
  70. ncbi Adhesive bond of veneering composites on various metal surfaces using silicoating, titanium-coating or functional monomers
    Michael Behr
    Department of Prosthodontics, University of Regensburg, Franz Josef Strauss Allee 11, 93053, Regensburg, Germany
    J Dent 31:33-42. 2003
    ....
  71. ncbi Shear bond strength of aesthetic materials bonded to Ni-Cr alloy
    Hercules Jorge Almilhatti
    Faculdade de Odontologia de Araraquara UNESP, Departamento de Materiais Odontológicos e Prótese, Rua Humaita, 1680 Araraquara, Sao Paulo 14801 903, Brazil
    J Dent 31:205-11. 2003
    ..This study was undertaken to evaluate the shear bond strength of four materials used as aesthetic material bonded to Ni-Cr alloy...
  72. ncbi Effect of blood contamination on shear bond strength of brackets bonded with conventional and self-etching primers
    Maria Francesca Sfondrini
    Department of Orthodontics, University of Pavia, 27100 Pavia, Italy
    Am J Orthod Dentofacial Orthop 125:357-60. 2004
    ..Significant differences in debond locations were found among the groups bonded with the 2 primers under the various enamel surface conditions...
  73. ncbi Effect of saliva on shear bond strength of an orthodontic adhesive used with moisture-insensitive and self-etching primers
    Irene L Zeppieri
    School of Dental Medicine, University of Pennsylvania, Philadephia 19104, USA
    Am J Orthod Dentofacial Orthop 124:414-9. 2003
    ....
  74. pmc An in vivo murine model of low-magnitude oscillatory wall shear stress to address the molecular mechanisms of mechanotransduction--brief report
    Nick J Willett
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Arterioscler Thromb Vasc Biol 30:2099-102. 2010
    ....
  75. ncbi Hemodynamic regulation of inflammation at the endothelial-neutrophil interface
    Julie Y Ji
    Department of Bioengineering, Institute for Medicine and Engineering, University of Pennsylvania, 1024 Vagelos Research Laboratory, 3340 Smith Walk, Philadelphia, PA 19104, USA
    Ann Biomed Eng 36:586-95. 2008
    ..Hemodynamic force exerts anti-inflammatory effects on cytokine-activated endothelium by attenuation of cytokine expression and neutrophil firm arrest...
  76. ncbi Bond strength of adhesive systems to dentin and enamel--human vs. bovine primary teeth in vitro
    Stephanie Krifka
    Department of Operative Dentistry and Periodontology, University of Regensburg, Germany
    Dent Mater 24:888-94. 2008
    ....
  77. ncbi Bond strength and debonding characteristics of a new ceramic bracket
    Jia Kuang Liu
    Department of Dentistry, National Cheng Kung University, 138 Sheng Li Road, Tainan 204, Taiwan, ROC
    Am J Orthod Dentofacial Orthop 128:761-5; quiz 802. 2005
    ....
  78. ncbi A full-range, multi-variable, CFD-based methodology to identify abnormal near-wall hemodynamics in a stented coronary artery
    Jonathan B Murphy
    Department of Mechanical Engineering, Dublin Institute of Technology, Dublin, Ireland
    Biorheology 47:117-32. 2010
    ..The hemodynamic performance of a stent can be assessed more comprehensively than with previously used methods by examining the arterial viscous stresses using the proposed methodology...
  79. ncbi Inflammatory responses of endothelial cells experiencing reduction in flow after conditioning by shear stress
    Nick M Matharu
    Division of Medical Sciences, The Medical School, University of Birmingham, UK
    J Cell Physiol 216:732-41. 2008
    ..Prolonged cessation of flow may increase the sensitivity of EC to inflammatory stimuli, but this effect may be suppressed by residual flow...
  80. ncbi Effect of thermal cycling on bond strengths of single-step self-etch adhesives to bovine dentin
    Yohei Asaka
    Nihon University Graduate School of Dentistry, Tokyo, Japan
    J Oral Sci 48:63-9. 2006
    ..Ten samples per group were tested for shear strength at a crosshead speed of 1.0 mm/min...
  81. ncbi Effect of light-tip distance on the shear bond strengths of composite resin
    Vittorio Cacciafesta
    Department of Orthodontics, University of Insubria, Varese, Italy
    Angle Orthod 75:386-91. 2005
    ..In hard-to-reach areas, the use of PAC system is suggested, whereas the LED evaluated in this study is not recommended...
  82. ncbi Effect of pre-etching enamel on fatigue of self-etch adhesive bonds
    Robert L Erickson
    Creighton University School of Dentistry, Omaha, NE, USA
    Dent Mater 24:117-23. 2008
    ..The objective of this study was to determine if pre-etching enamel would substantially improve the SBS and SFL of the PLP adhesive over those found in the previous study...
  83. ncbi Shear bond strength of dual-cured and self-cured resin composites to dentin using different bonding agents and techniques
    C Leevailoj
    Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
    Oper Dent 32:149-59. 2007
    ..017). Light activation of the bonding agents prior to applying the resin composites led to a significantly higher shear bond strength of the resin composites to dentin, compared to no light activation (p < 0.05)...
  84. pmc Spatial regulation of inflammation by human aortic endothelial cells in a linear gradient of shear stress
    Jean K Tsou
    Department of Biomedical Engineering, University of California, Davis, California, USA
    Microcirculation 15:311-23. 2008
    ..This study aimed to understand how endothelial cells sense a gradient of fluid shear stress and transduce signals that regulate membrane expression of cell adhesion molecules and monocyte recruitment...
  85. ncbi Shear bond strength of metallic orthodontic brackets bonded to enamel prepared with Self-Etching Primer
    Fabio Lourenco Romano
    Piracicaba Dental School Unicamp, Ribeirao Preto, Sao Paulo, Brazil
    Angle Orthod 75:849-53. 2005
    ..The Transbond XT conventionally bonded showed better adhesion results than Transbond XT, Z-100, and Concise Orthodontic after using Transbond Plus Self-Etching Primer...
  86. pmc Statistical wall shear stress maps of ruptured and unruptured middle cerebral artery aneurysms
    L Goubergrits
    Biofluid Mechanics Laboratory, Charite Universitatsmedizin Berlin, Berlin, Germany
    J R Soc Interface 9:677-88. 2012
    ..Our results confirm the hypothesis of low WSS and irregular shape as the essential rupture risk parameters...
  87. ncbi Enamel conditioning for orthodontic bonding with a single-step bonding agent
    Heike Korbmacher
    Department of Orthodontics, University of Hamburg, Germany
    J Orofac Orthop 63:463-71. 2002
    ..In-vitro evaluation of an alternative method to the conventional acid etch technique...
  88. ncbi Comparison of bonding time and shear bond strength between a conventional and a new integrated bonding system
    Samir E Bishara
    Orthodontic Department, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA
    Angle Orthod 75:237-42. 2005
    ..The clinician has to decide whether the increase in bond strength, the decrease in the total bonding time, and the steps saved during the bonding procedure with the new bonding system balance the increased cost incurred...
  89. ncbi Effect of water storage on the shear strength and fatigue limit of the reline resin bond to denture base resins
    Carlos Eduardo Vergani
    Department of Dental Materials and Prosthodontics, Sao Paulo State University UNESP, Araraquara Dental School, SP, Brazil
    J Adhes Dent 12:319-27. 2010
    ..This study evaluated the effect of water storage (WS) on the shear bond strength (SBS) and shear bond fatigue limit (SBFL) between denture base and reline resins. In addition, a possible correlation between SBS and SBFL was evaluated...
  90. ncbi Effect of thermal cycling on enamel bond strength of single-step self-etch systems
    Shino Amano
    Nihon University, School of Dentistry, Department of Operative Dentistry, Tokyo, Japan
    Oper Dent 31:616-22. 2006
    ..With a careful choice of adhesive systems, the benefit to using single-step self-etch systems in terms of simplifying the clinical procedure might be acceptable, even after thermal stresses...
  91. ncbi Shear stress effect on transfection of neurons cultured in microfluidic devices
    Hwa Sung Shin
    Department of Biological Engineering, Inha University, Incheon 402 751, Korea
    J Nanosci Nanotechnol 9:7330-5. 2009
    ....
  92. ncbi Effects of cardiac motion on right coronary artery hemodynamics
    Dehong Zeng
    Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada
    Ann Biomed Eng 31:420-9. 2003
    ..The hemodynamic effects of RCA motion can, therefore, be ignored as a first approximation in modeling studies...
  93. ncbi Effects of a chlorhexidine varnish on shear bond strength in indirect bonding
    Omur Polat
    Department of Orthodontics, Faculty of Dentistry, Baskent University, Ankara, Turkey
    Angle Orthod 75:1036-40. 2005
    ....
  94. ncbi Shear bond strength of self-etching and total-etch adhesive systems to Er:YAG laser-irradiated primary dentin
    Carolina Paes Torres
    Department of Pediatric Clinics, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
    J Dent Child (Chic) 76:67-73. 2009
    ..The purpose of this study was to assess in vitro the shear bond strength of self-etching and total-etch adhesive systems to Er:YAG laser-irradiated primary dentin...
  95. ncbi Effects of different chlorhexidine formulations on shear bond strengths of orthodontic brackets
    Bulent Catalbas
    Department of Orthodontics, University of Kirikkale, Kirikkale, Turkey
    Angle Orthod 79:312-6. 2009
    ..To test the hypothesis that the application of different chlorhexidine formulations to the etched enamel will not affect shear bond strength (SBS)...
  96. ncbi Effects of elastic property of the wall on flow characteristics through arterial stenoses
    M S Moayeri
    Department of Mechanical Engineering, Shiraz University, Shiraz, Iran
    J Biomech 36:525-35. 2003
    ..The results indicate that deformability of the wall causes an increase in the time average of pressure drop, but a decrease in the maximum wall shear stress. Displacement and stress distributions in the wall are presented...
  97. ncbi Effectiveness of a hydrophilic primer when different antimicrobial agents are mixed
    Ali Ihya Karaman
    Selcuk University, School of Dentistry, Department of Orthodontics, Konya, Turkey
    Angle Orthod 74:414-9. 2004
    ..Application of different antimicrobial agents may result in differences in the site of failure...
  98. ncbi The incorporation of a zone of calcified cartilage improves the interfacial shear strength between in vitro-formed cartilage and the underlying substrate
    Jean Philippe St-Pierre
    CIHR BioEngineering of Skeletal Tissues Team, Mount Sinai Hospital, Canada M5G 1X5
    Acta Biomater 8:1603-15. 2012
    ..The generation of a ZCC at the cartilage-CPP interface led to a 3.3-fold increase in the interfacial shear strength of biphasic constructs...
  99. pmc Effect of self-etching primer/adhesive and conventional bonding on the shear bond strength in metallic and ceramic brackets
    Behnam Mirzakouchaki
    Orthodontic Department, TMSU, Tabriz, Iran
    Med Oral Patol Oral Cir Bucal 17:e164-70. 2012
    ..Bracket debonding from the tooth surface is a common problem in fixed orthodontics. The aims of the present study were to assess the bond strength and failure sites in two ways of bonding technique, with metallic and ceramic brackets...
  100. ncbi High rate shear insult delivered to cortical neurons produces heterogeneous membrane permeability alterations
    Michelle C LaPlaca
    Biomed Eng Dept, Georgia Inst of Technol, Atlanta, GA 30332 0535, USA
    Conf Proc IEEE Eng Med Biol Soc 1:2384-7. 2006
    ..This approach provides an experimental framework to investigate injury tolerance criteria as well as mechanistically driven therapeutic strategies...
  101. ncbi Localized elevation of shear stress is related to coronary plaque rupture: a 3-dimensional intravascular ultrasound study with in-vivo color mapping of shear stress distribution
    Yusaku Fukumoto
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan
    J Am Coll Cardiol 51:645-50. 2008
    ..The purpose of the present study was to assess the relationship between shear stress distribution and coronary plaque rupture by means of a new color-mapping program of shear stress with 3-dimensional intravascular ultrasound (IVUS)...

Research Grants67

  1. FAILURE MECHANISMS OF REVISION JOINT REPLACEMENT
    Joan E Bechtold; Fiscal Year: 2013
    ..Fixation is determined mechanically (static and dynamic shear strength, stiffness and energy and damping modulus), histomorphometrically (bone ongrowth, % bone in peri-implant space,..
  2. INTERLAKEN SERIES 3000 AXIAL-TORSIONAL MATERIALS TESTING
    Wilson Hayes; Fiscal Year: 1992
    ..cartilage, which would in turn be related to extracellular matrix synthesis, assembly and catabolism; 7) The shear strength between calcium phosphate coatings and a metallic substrate will be evaluated by torsional tests of ..
  3. FAILURE MECHANISMS OF REVISION JOINT REPLACEMENT
    Joan Bechtold; Fiscal Year: 2000
    ..Analyses and intergroup comparisons (Years 4-5) will be conducted for implant/interface shear strength, fibrous membrane thickness, bone ingrowth, and presence of macrophages, fibroblasts, synovial cells, foreign ..
  4. LASER ACOUSTIC EVALUATION OF DENTAL MATERIALS BONDING
    EVAN GREENER; Fiscal Year: 1993
    ..techniques, which include the compressive and diametral tensile tests in the case of composites, and shear strength measurements in the case of dentin bonding, to determine the extent of correlation...
  5. S. aureus Enhances Interaction with Biomaterials
    Michael Hudson; Fiscal Year: 2004
    ..3. Does UV-killed S. aureus enhance interfacial shear strength between bone and titanium implants in vivo? An in vivo model is proposed to address this aim...
  6. PMMA PRECOATED INTRAMEDULLARY IMPLANTS
    Joon Park; Fiscal Year: 1980
    ..of load from implant to bone, improves intramedullary centering of the prosthesis and increases interfacial shear strength over the same prosthesis and conventional implantation methods...
  7. INTERFACIAL PROPERTIES OF HAVERSIAN BONE
    LANNY GRIFFIN; Fiscal Year: 2002
    ..The goal of this study is to quantitatively investigate properties, such as fracture toughness and shear strength, of major interfaces in cortical bone, such as cement lines and interlamellar interfaces of osteons...
  8. WALL SHEAR STRESS IN THE CARDIOVASCULAR SYSTEM
    JOHN TARBELL; Fiscal Year: 2003
    ....
  9. SHEAR STRESS EFFECTS ON ENDOTHELIAL TRANSPORT
    John M Tarbell; Fiscal Year: 2010
    ..abstract_text> ..
  10. CCNY/MSKCC BIOMEDICAL ENGINEERING PARTNERSHIP
    JOHN TARBELL; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  11. LASER DOPPLER VELOCIMETER SYSTEM FOR BIOMEDICAL STUDIES
    JOHN TARBELL; Fiscal Year: 2001
    ..The system will be the primary measurement system for the ongoing research in cardiovascular prosthetics including mechanical heart valve cavitation and ventricular assist devices. ..
  12. Methyl Mercury Evaluation in Dental Waste Water
    James Drummond; Fiscal Year: 2003
    ..Hypothesis: Element mercury released in DWW is converted to Hg(lI) and then in more limited amounts to methyl-mercury by specific biofilm bacterial species in the Dental sewage pipes. ..
  13. Assessment of Tissue Response to Stress
    Joan Sanders; Fiscal Year: 2006
    ..this technology could be applied to other areas of rehabilitation, for example, shoe design for patients with insensate feet, cushion design for wheelchair users, and mattress design for bedridden patients [unreadable] [unreadable]..
  14. Stem Cell-Seeded ECM Scaffolds for Neurotransplantation
    MICHELLE LAPLACA; Fiscal Year: 2004
    ..abstract_text> ..
  15. VASCULAR FUNCTION BY MAGNETIC RESONANCE ANGIOGRAPHY
    HARRY SILBER; Fiscal Year: 2005
    ..abstract_text> ..
  16. Cell and molecular studies in cardiovascular engineering
    Peter Davies; Fiscal Year: 2005
    ....
  17. Skin Adaptation to Mechanical Stress
    Joan Sanders; Fiscal Year: 2006
    ..By understanding the process of skin adaptation (natural skin strengthening) at both a cellular and molecular level, therapies to encourage skin adaptation before breakdown occurs can be intelligently pursued. ..
  18. INTERFACE MECHANICS, MATERIALS AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2007
    ..The development of methods to predict and overcome the detrimental effects of residual limb shape change and ultimately prevent soft-tissue breakdown will help to prevent secondary disability and morbidity in the amputee population. ..
  19. MOLECULAR MECHANISMS CELL COMMUNICATIONS/ATHEROGENESIS
    Peter Davies; Fiscal Year: 2002
    ..These studies will address a poorly understood mechanism of vascular cell communication at the tissue, cell and molecular level as a function of atherogenesis. ..
  20. INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2003
    ....
  21. INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2002
    ....
  22. NEW BIOMATERIALS TO MINIMIZE SCAR TISSUE FORMATION
    Joan Sanders; Fiscal Year: 2002
    ..e. soft-tissue complications that require surgical repair through use of a biomaterial. The new materials will prevent scar tissue formation and reduce the occurrence of secondary complications. ..
  23. Regulation of Transepithelial Transport in PKD
    Rajeev Rohatgi; Fiscal Year: 2008
    ..SA II: To identify those factors that regulate the avid Na absorption seen in ARPKD cyst lining epithelial cells. ..
  24. Osteoblast stimulation effects on osteoclast activity
    Marnie Saunders; Fiscal Year: 2006
    ..This work has several clinically relevant applications including implant- and metastatic-induced osteolysis, osteoporosis, osteopetrosis, fracture healing and functional tissue engineering. ..
  25. Magnetic quantum dots for active sensing of the nuclear envelope
    Denis Wirtz; Fiscal Year: 2008
    ..3d. We will investigate whether and how the actin and microtubule networks affect the mechanical properties of the NE. [unreadable] [unreadable] [unreadable]..
  26. Image-guided Ultrasound-triggered Tumor Therapy
    Alexander Klibanov; Fiscal Year: 2007
    ..Monitor blood flow within the tumor after treatment. Perform final optimization of the drug carrier formulation and ultrasound activation parameters. ..
  27. MECHANICALLY-INDUCED REMODELING OF TISSUE ENGINEERED BLOOD VESSELS
    RUDOLPH GLEASON; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  28. Augmentation of Lymphangiogenesis by Increased Fluid Channeling in Mouse Skin
    Jeremy Goldman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  29. New bioreactor-based approach to stem cell/progenitor expansion for cell therapie
    Stephen Navran; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  30. MULTIAXIAL STRENGTH BEHAVIOR OF HUMAN TRABECULAR BONE
    Tony M Keaveny; Fiscal Year: 2010
    ..This project should provide substantial insight into the roles of trabecular bone strength and bone quality on osteoporotic fracture risk and treatment and other orthopedic applications. ..
  31. Aging and Fatigue Crack Growth in Dentin
    DWAYNE DALE AROLA; Fiscal Year: 2010
    ..These achievements should reduce the incidence of restorative failures associated with tooth fracture, resulting in billions of dollars in savings of health care costs, as well as a reduction in human suffering. ..
  32. Multiscale modeling of leukocyte-tumor cell adhesion to endothelium in shear flow
    Cheng Dong; Fiscal Year: 2010
    ....
  33. Optimizing Osteotropism of Human Mesenchymal Stem Cells
    Robert Sackstein; Fiscal Year: 2010
    ....
  34. Spatiotemporal Progression of Meniscal Degradation
    Marc E Levenston; Fiscal Year: 2010
    ..These studies will provide important new insights into the progression of meniscal degeneration and could lead to novel diagnostic or therapeutic targets to prevent or delay the progression of OA. ..
  35. BIOEFFECTS OF GAS BODY ACTIVATION IN MEDICAL ULTRASOUND
    Douglas Miller; Fiscal Year: 2009
    ..This project will examine bioeffects in cells and tissues and show how to safely use ultrasound contrast agents in diagnostic imaging. ..
  36. RESIN-BASED REMINERALIZING CEMENTS AND COMPOSITES
    SABINE DICKENS; Fiscal Year: 2009
    ..Completion of this research will lead to Ca- PO4 cements and composites with improved adhesion to dentin and improved strength for ART and the treatment of root caries. ..
  37. The Regulation of VEGF-C by Interstitial Flow
    Jeremy Goldman; Fiscal Year: 2008
    ..Therefore, we aim to determine whether an augmentation of fluid channel formation will increase interstitial flow and promote functional lymphangiogenesis in experimental lymphedema. [unreadable] [unreadable] [unreadable]..
  38. Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain
    Helene M Langevin; Fiscal Year: 2010
    ....
  39. Regional Assessment of the Lung Using Magnetic Resonance Elastography (MRE)
    KIARAN PATRICK MCGEE; Fiscal Year: 2010
    ..abstract_text> ..
  40. Mechanical Feedback on Cell Structure and Signaling
    Shu Chien; Fiscal Year: 2010
    ..The results generated from these proposed studies will provide insight into the cellular adaptation mechanisms and homeostasis of biological functions in responses to stretch. ..
  41. Induction of Tissue Factor by Patient Sera in HUS
    Eric Grabowski; Fiscal Year: 2007
    ..A key additional feature of this proposal is the use of our newly formed collaborative group of pediatric nephrologists to facilitate patient recruitment [unreadable] [unreadable]..
  42. BIOMECHANICAL/PSYCHOSOCIAL RISKS FOR LOW BACK DISORDERS
    William Marras; Fiscal Year: 2003
    ..We will also be able to discern when and under what conditions an intervention to improve the psycho social work environment will be likely to reduce LBP and its associated morbidity. ..
  43. PLATELET INTERACTIONS WITH ENDOTHELIUM AND LEUKOCYTES
    Jose Lopez; Fiscal Year: 2004
    ..The experiments proposed in this application will test these hypotheses in model systems and in vivo and will characterize in detail the interactions between gpIb and P-selectin, L-selectin, and Mac-1. ..
  44. An organotypic model of traumatic brain injury
    Michael Bottlang; Fiscal Year: 2004
    ..abstract_text> ..
  45. Methods for Improving Pancreatic Islet Transplantation
    Stephen Navran; Fiscal Year: 2004
    ..c) Viability assessed by a battery of assays. After optimization of islet culture in the perfused RCCS using rat islets in phase I, the procedures will be applied to human islets in phase II and tested in an animal model of diabetes. ..
  46. Functional Tissue Factor on Activated Endothelium
    Eric Grabowski; Fiscal Year: 2004
    ....
  47. DETERMINANTS OF DYNAMICS OF CELL ADHESION UNDER FLOW
    Daniel Hammer; Fiscal Year: 2003
    ..These microspheres can be coated with adhesive ligands that code for rolling or firm adhesion , and can be used for the treatment of vascular diseases. ..
  48. Fatigue and the Endurance Strength of Dentin
    Dwayne Arola; Fiscal Year: 2003
    ..Therefore, results from this study could have tremendous impact on the clinical techniques and procedures used for restorative dentistry. ..
  49. LOAD INDUCED DISC DEGENERATION IN A RAT TAIL MODEL
    James Iatridis; Fiscal Year: 2003
    ..abstract_text> ..
  50. ULTRASOUND ENHANCEMENT OF CANCER GENE THERAPY
    Douglas Miller; Fiscal Year: 2003
    ..This research will provide a bridge from the basic research breakthrough to specific therapeutic applications and urgently needed clinical research programs utilizing this novel technology. ..
  51. Molecular Mechanism of Endothelial Migration Under Flow
    Shu Chien; Fiscal Year: 2004
    ..abstract_text> ..
  52. Histo-Mechanics & Biology of Remodeling in Hypertension
    JAY HUMPHREY; Fiscal Year: 2005
    ..Subsequent parallel studies will focus on additional pharmacological agents and gender-related differences. ..
  53. A Novel Load Sensing Tibial Prosthesis Design
    DARRYL D LIMA; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  54. Root deformation and root resorption
    Thomas Katona; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  55. MAGNETIC RESONANCE CORONARY ANGIOGRAPHY
    John Oshinski; Fiscal Year: 2001
    ....
  56. IMPROVED PREVENTIVE/RESTORATIVE RESINS AND COMPOSITES
    SABINE DICKENS; Fiscal Year: 2006
    ..The data gathered in these experiments will serve to support a larger R01 grant application with the long-term objectives of developing improved durable materials for adhesives and adhesive composites. [unreadable] [unreadable]..
  57. Neutrophil-Mediated Melanoma Cell Adhesion and Migration
    Cheng Dong; Fiscal Year: 2006
    ..Furthermore, since adhesion is a critical step in tumor metastasis these studies may identify novel therapeutic targets against invasive melanomas. [unreadable] [unreadable]..
  58. Mapping the Mechanical Properties of the Diabetic Foot
    John Weaver; Fiscal Year: 2006
    ..abstract_text> ..
  59. Mechanical Stretch and Vein Graft Intimal Hyperplasia
    Jeremy Goldman; Fiscal Year: 2005
    ..Specific Aim II: Investigate the role of platelet-derived growth factor (PDGF)-BB and related signaling molecules in mediating subsequent vascular cell proliferation. ..
  60. Biodurability of Dentin-Adhesive Resin Bond Joint
    Steven Armstrong; Fiscal Year: 2003
    ..abstract_text> ..
  61. A Validated Micro-Structural Mechanical Model of Coronary Arteries
    Ghassan S Kassab; Fiscal Year: 2010
    ....
  62. Pressure and Flow-Induced Remodeling of Coronary Arteries
    Ghassan S Kassab; Fiscal Year: 2010
    ..The long-term goal of this research is to develop optimal therapies to restore the oxidative balance in CAD. ..
  63. Characterization of A Novel 65kDa E-selectin Ligand on G-CSF Mobilized Leukocytes
    Robert Sackstein; Fiscal Year: 2008
    ..It is anticipated that the results obtained will lead to new approaches for preventing or alleviating G-CSF-induced vascular and inflammatory complications [unreadable] [unreadable] [unreadable]..
  64. ADHESION MOLECULES MEDIATING SKIN TROPISM IN ACUTE GVHD
    Robert Sackstein; Fiscal Year: 2003
    ....
  65. Structure & Biology of Hematopoietic E-/L-Selectin
    Robert Sackstein; Fiscal Year: 2006
    ..This information will contribute greatly to our understanding of the adhesive systems that regulate steady-state and pathologic hematopoiesis, as well as hematopoietic recovery following stem cell transplantation. ..
  66. Optimizing Cardiovascular Devices Thrombogenicity for Eliminating Anticoagulation
    Danny Bluestein; Fiscal Year: 2009
    ..It is envisioned that it will also facilitate the use of these devices for long term therapy by reducing the need for difficult pharmacological management with anticoagulants, which is mandated for most existing devices. ..