fourier analysis

Summary

Summary: Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992)

Top Publications

  1. pmc Metabolomics reveals metabolic biomarkers of Crohn's disease
    Janet Jansson
    Ecology Department, Division of Earth Sciences, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS ONE 4:e6386. 2009
  2. ncbi Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range
    Michalina Gora
    Institute of Physics, Nicolaus Copernicus University, ul Grudziadzka 5 7, PL 87 100 Torun, Poland
    Opt Express 17:14880-94. 2009
  3. ncbi The structure of the potassium channel: molecular basis of K+ conduction and selectivity
    D A Doyle
    Laboratory of Molecular Neurobiology and Biophysics and the Howard Hughes Medical Institute, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 280:69-77. 1998
  4. pmc The contribution of gliosis to diffusion tensor anisotropy and tractography following traumatic brain injury: validation in the rat using Fourier analysis of stained tissue sections
    Matthew D Budde
    Neuroscience Research Centre, Milwaukee, WI 53226, USA
    Brain 134:2248-60. 2011
  5. pmc Fourier analysis and systems identification of the p53 feedback loop
    Naama Geva-Zatorsky
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel
    Proc Natl Acad Sci U S A 107:13550-5. 2010
  6. pmc Insulin sensitivity is reflected by characteristic metabolic fingerprints--a Fourier transform mass spectrometric non-targeted metabolomics approach
    Marianna Lucio
    Department of BioGeoChemistry and Analytics, Institute for Ecological Chemistry, Helmholtz Zentrum Muenchen German Research Center for Environmental Health, Neuherberg, Germany
    PLoS ONE 5:e13317. 2010
  7. pmc Predicting housekeeping genes based on Fourier analysis
    Bo Dong
    Bioinformatics Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People s Republic of China
    PLoS ONE 6:e21012. 2011
  8. ncbi Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies
    Yaron Har-Shai
    Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Wound Repair Regen 14:18-27. 2006
  9. ncbi Collagen bundle morphometry in skin and scar tissue: a novel distance mapping method provides superior measurements compared to Fourier analysis
    Pauline D H M Verhaegen
    Association of Dutch Burn Centres, Beverwijk, The Netherlands
    J Microsc 245:82-9. 2012
  10. pmc Real-time 4D signal processing and visualization using graphics processing unit on a regular nonlinear-k Fourier-domain OCT system
    Kang Zhang
    Department of Electrical and Computer Engineering, The Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
    Opt Express 18:11772-84. 2010

Research Grants

  1. Mechanics of Inner Ear Hair Bundles
    KIRIAKI DOMENICA KARAVITAKI; Fiscal Year: 2012
  2. Placental shape features, gestational timing and maternal and infant health
    Carolyn M Salafia; Fiscal Year: 2011
  3. FIBER CELL JUNCTIONS IN NORMAL AND CATARACTOUS LENSES
    M Joseph Costello; Fiscal Year: 2011
  4. IMMUNOGLOBULINS IN MULTIPLE MYELOMA & AMYLOIDOSIS
    Allen Edmundson; Fiscal Year: 1993
  5. A NEW METHOD FOR ANALYSIS OF CORONARY ARTERY BEHAVIOR
    Thomas Williams; Fiscal Year: 1980
  6. Quantifying Left Ventricular Ejection Effectiveness
    Michael Pinsky; Fiscal Year: 2007
  7. Surgical Monitor for Detection of Spinal Cord Injury
    ANANTH NATARAJAN; Fiscal Year: 2003
  8. ANALYSIS OF FLICKER RETINAL ACTION POTENTIALS
    ROBERT DE VOE; Fiscal Year: 1990
  9. INTRAORAL PRESSURE VARIATIONS--THE PALATAL MICROPHONE
    JOHN SEIKEL; Fiscal Year: 1992
  10. TRANSMISSION ELECTRON MICROSCOPE--PHILIPS CM120
    M Costello; Fiscal Year: 1999

Detail Information

Publications358 found, 100 shown here

  1. pmc Metabolomics reveals metabolic biomarkers of Crohn's disease
    Janet Jansson
    Ecology Department, Division of Earth Sciences, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS ONE 4:e6386. 2009
    ..Our data reveal novel differentiating metabolites for CD that may provide diagnostic biomarkers and/or monitoring tools as well as insight into potential targets for disease therapy and prevention...
  2. ncbi Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range
    Michalina Gora
    Institute of Physics, Nicolaus Copernicus University, ul Grudziadzka 5 7, PL 87 100 Torun, Poland
    Opt Express 17:14880-94. 2009
    ..Additionally, a volumetric and real time reconstruction of dynamic processes, like pupillary reaction to light stimulus or blink-induced contact lens movements are demonstrated...
  3. ncbi The structure of the potassium channel: molecular basis of K+ conduction and selectivity
    D A Doyle
    Laboratory of Molecular Neurobiology and Biophysics and the Howard Hughes Medical Institute, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 280:69-77. 1998
    ..The architecture of the pore establishes the physical principles underlying selective K+ conduction...
  4. pmc The contribution of gliosis to diffusion tensor anisotropy and tractography following traumatic brain injury: validation in the rat using Fourier analysis of stained tissue sections
    Matthew D Budde
    Neuroscience Research Centre, Milwaukee, WI 53226, USA
    Brain 134:2248-60. 2011
    ..We developed a method to quantify the anisotropy of stained histological sections using Fourier analysis, and applied the method to a rat controlled cortical impact model to identify the specific pathological ..
  5. pmc Fourier analysis and systems identification of the p53 feedback loop
    Naama Geva-Zatorsky
    Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel
    Proc Natl Acad Sci U S A 107:13550-5. 2010
    ..It seems to be a useful way to find the in vivo design of circuits and may be applied to other systems by monitoring their power spectrum in individual cells...
  6. pmc Insulin sensitivity is reflected by characteristic metabolic fingerprints--a Fourier transform mass spectrometric non-targeted metabolomics approach
    Marianna Lucio
    Department of BioGeoChemistry and Analytics, Institute for Ecological Chemistry, Helmholtz Zentrum Muenchen German Research Center for Environmental Health, Neuherberg, Germany
    PLoS ONE 5:e13317. 2010
    ....
  7. pmc Predicting housekeeping genes based on Fourier analysis
    Bo Dong
    Bioinformatics Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People s Republic of China
    PLoS ONE 6:e21012. 2011
    ..They play an important role in the normalization of microarray technology. Using Fourier analysis we transformed gene expression time-series from a Hela cell cycle gene expression dataset into Fourier ..
  8. ncbi Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies
    Yaron Har-Shai
    Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Wound Repair Regen 14:18-27. 2006
    ....
  9. ncbi Collagen bundle morphometry in skin and scar tissue: a novel distance mapping method provides superior measurements compared to Fourier analysis
    Pauline D H M Verhaegen
    Association of Dutch Burn Centres, Beverwijk, The Netherlands
    J Microsc 245:82-9. 2012
    ..Nevertheless, in the future, both methods can be used for reliable and valid collagen morphometry of skin and scars, whereas further applications evaluating the quantitative microscopy of other fibrotic processes are anticipated...
  10. pmc Real-time 4D signal processing and visualization using graphics processing unit on a regular nonlinear-k Fourier-domain OCT system
    Kang Zhang
    Department of Electrical and Computer Engineering, The Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
    Opt Express 18:11772-84. 2010
    ..This technique is highly cost-effective and can be easily integrated into most ultrahigh speed FD-OCT systems to overcome the 3D data processing and visualization bottlenecks...
  11. ncbi First-in-man evaluation of intravascular optical frequency domain imaging (OFDI) of Terumo: a comparison with intravascular ultrasound and quantitative coronary angiography
    Takayuki Okamura
    Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
    EuroIntervention 6:1037-45. 2011
    ..The Terumo-OFDI system is capable of acquiring images with high-speed automated pullback (up to 40 mm/sec) and requires only a short injection (3-4 sec) of small amount of x-ray contrast (9-16 ml)...
  12. ncbi Reproducibility of coronary Fourier domain optical coherence tomography: quantitative analysis of in vivo stented coronary arteries using three different software packages
    Takayuki Okamura
    Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
    EuroIntervention 6:371-9. 2010
    ..We tested the reproducibility of in vivo, intracoronary FD OCT and assessed the influence of different computer-assisted algorithms on quantitative analysis...
  13. pmc Pilot study of optical coherence tomography measurement of retinal blood flow in retinal and optic nerve diseases
    Yimin Wang
    Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Invest Ophthalmol Vis Sci 52:840-5. 2011
    ..To investigate blood flow changes in retinal and optic nerve diseases with Doppler Fourier domain optical coherence tomography (OCT)...
  14. ncbi 13C isotope-labeled metabolomes allowing for improved compound annotation and relative quantification in liquid chromatography-mass spectrometry-based metabolomic research
    Patrick Giavalisco
    Max Planck Institut fur Molekulare Pflanzenphysiologie, Am Muhlenberg 1, 14476 Potsdam Golm, Germany
    Anal Chem 81:6546-51. 2009
    ....
  15. ncbi Optimisation of the 3D MDEFT sequence for anatomical brain imaging: technical implications at 1.5 and 3 T
    R Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London WC1N 3BG, UK
    Neuroimage 21:757-67. 2004
    ..It is shown both theoretically and experimentally that these problems can be avoided by using spin tagging and fat saturation...
  16. ncbi Spectral Repeat Finder (SRF): identification of repetitive sequences using Fourier transformation
    Deepak Sharma
    Department of Biotechnology, All India Institute of Medical Sciences, New Delhi 110029, India
    Bioinformatics 20:1405-12. 2004
    ..A major difficulty in identification of repeats arises from the fact that the repeat units can be either exact or imperfect, in tandem or dispersed, and of unspecified length...
  17. ncbi Fourier-domain low-coherence interferometry for light-scattering spectroscopy
    Adam Wax
    Department of Biomedical Engineering and the Fitzpatrick Center for Photonics, Duke University, Durham, North Carolina 27708, USA
    Opt Lett 28:1230-2. 2003
    ..Application of the technique to probing the size of cell nuclei in living epithelial tissues is discussed...
  18. ncbi Frequency domain algorithm for quantifying atrial fibrillation organization to increase defibrillation efficacy
    T H Everett
    Department of Internal Medicine, University of Virginia Health System, Charlottesville 22908, USA
    IEEE Trans Biomed Eng 48:969-78. 2001
    ..8 for a 1-s window, and improved to 0.9 for a 4-s window. We conclude that the spectrum of an AF signal contains information relating to its organization, and can be used in predicting a successful defibrillation...
  19. ncbi Presence of left-to-right atrial frequency gradient in paroxysmal but not persistent atrial fibrillation in humans
    Sorin Lazar
    Electrophysiology Division, Department of Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA
    Circulation 110:3181-6. 2004
    ..We hypothesized that human AF would also manifest a left-to-right atrial frequency gradient...
  20. ncbi RR interval dynamics before atrial fibrillation in patients after coronary artery bypass graft surgery
    C W Hogue
    Department of Anesthesiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Circulation 98:429-34. 1998
    ..Because nonlinear methods of HRV analysis provide information about heart rate dynamics not evident from usual HRV measures, we also hypothesized that approximate entropy (ApEn), a nonlinear measure of HRV, might have predictive value...
  21. pmc REPETITA: detection and discrimination of the periodicity of protein solenoid repeats by discrete Fourier transform
    Luca Marsella
    CECAM, Lyon, France
    Bioinformatics 25:i289-95. 2009
    ....
  22. pmc Classification and 3D averaging with missing wedge correction in biological electron tomography
    A Bartesaghi
    Center for Cancer Research, National Institutes of Health, Building 50, Room 4306, Bethesda, MD 20892, USA
    J Struct Biol 162:436-50. 2008
    ....
  23. ncbi Predicting the distribution of tsetse flies in West Africa using temporal Fourier processed meteorological satellite data
    D J Rogers
    Department of Zoology, University of Oxford
    Ann Trop Med Parasitol 90:225-41. 1996
    ..Refinements of the analytical technique and the problems of extending the predictions through space and time are discussed...
  24. ncbi Power vectors: an application of Fourier analysis to the description and statistical analysis of refractive error
    L N Thibos
    School of Optometry, Indiana University, Bloomington, USA
    Optom Vis Sci 74:367-75. 1997
    The description of sphero-cylinder lenses is approached from the viewpoint of Fourier analysis of the power profile...
  25. pmc Electron tomography, three-dimensional Fourier analysis and colour prediction of a three-dimensional amorphous biophotonic nanostructure
    Matthew D Shawkey
    Department of Biology and Integrated Bioscience Program, University of Akron, Akron, OH 44325 3908, USA
    J R Soc Interface 6:S213-20. 2009
    ..Tomography and three-dimensional Fourier analysis reveal that it is an amorphous, interconnected bicontinuous matrix that is appropriately ordered at local ..
  26. ncbi Collagen morphology in human skin and scar tissue: no adaptations in response to mechanical loading at joints
    Paul P M van Zuijlen
    Burn Centre and Department of Surgery, Red Cross Hospital, Vondellaan 13, 1942 LE Beverwijk, The Netherlands
    Burns 29:423-31. 2003
    ..Scar tissue and normal skin were biopsied from joints and control areas and evaluated by the Fourier analysis. Collagen orientation was represented by an index ranging from 0 (perfectly random) to 1 (perfectly parallel)...
  27. pmc Definition and estimation of resolution in single-particle reconstructions
    Hstau Y Liao
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Structure 18:768-75. 2010
    ..Finally, the drawbacks of resolution estimation are entirely avoided by computing the correlation of neighboring voxels in the Fourier domain...
  28. pmc The vibrations of texture
    Sliman J BensmaIa
    University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Somatosens Mot Res 20:33-43. 2003
    ..On the other hand, the effects of speed on roughness match those of speed on power. We propose that the roughness of a fine surface (spatial period<200 microm) is a function of the Pacinian-weighted power of the vibrations it elicits...
  29. ncbi Adaptive estimation of EEG for subject-specific reactive band identification and improved ERD detection
    Yubo Wang
    College of IT Engineering, Kyungpook National University, Daegu 702 701, South Korea
    Neurosci Lett 528:137-42. 2012
    ..Study conducted with 8 subjects drawn from BCI Competition IV data set show a 22% increase in ERD and 10% improvement in classification with the proposed method compared to standard ERD based classification...
  30. pmc Time-frequency analysis of movement-related spectral power in EEG during repetitive movements: a comparison of methods
    David P Allen
    Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 N Michigan Avenue, Suite 1100, Chicago, IL 60611, USA
    J Neurosci Methods 186:107-15. 2010
    ....
  31. ncbi Spatial-frequency and contrast properties of crowding
    S T Chung
    School of Optometry, Indiana University, Bloomington, IN, USA
    Vision Res 41:1833-50. 2001
    ....
  32. ncbi Progression of keratoconus assessed by fourier analysis of videokeratography data
    Tetsuro Oshika
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ophthalmology 109:339-42. 2002
    ..To quantitatively document changes in corneal refractive parameters in relation to the progression of keratoconus over years...
  33. ncbi Non-uniform frequency domain for optimal exploitation of non-uniform sampling
    Krzysztof Kazimierczuk
    Faculty of Chemistry, University of Warsaw, Pasteura 1, 02 093 Warsaw, Poland
    J Magn Reson 205:286-92. 2010
    ..COSY multiplets. Spectral data acquired with the use of proposed techniques allow easy assignment of protein backbone resonances and precise determination of coupling constants...
  34. ncbi Bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities in human retinal vessels
    René M Werkmeister
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Opt Lett 33:2967-9. 2008
    ..We demonstrate that bidirectional color Doppler optical coherence tomography allows for the measurement of absolute blood flow values in vivo in human retinal vessels...
  35. ncbi Magnetic flux density reconstruction using interleaved partial Fourier acquisitions in MREIT
    Hee Myung Park
    Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Korea
    Phys Med Biol 56:2059-73. 2011
    ....
  36. ncbi Rapid visual categorization of natural scene contexts with equalized amplitude spectrum and increasing phase noise
    Olivier R Joubert
    Centre de Recherche Cerveau et Cognition, Universite de Toulouse, UPS, France
    J Vis 9:2.1-16. 2009
    ..This two-phase strategy could maximize categorization performance if the diagnostic features of man-made environments tolerate higher levels of noise than natural features, as proposed recently...
  37. ncbi Do's and don'ts in Fourier analysis of steady-state potentials
    M Bach
    Elektrophysiologisches Labor, Universitats Augenklinik, Freiburg, Germany
    Doc Ophthalmol 99:69-82. 1999
    b>Fourier analysis is a powerful tool in signal analysis that can be very fruitfully applied to steady-state evoked potentials (flicker ERG, pattern ERG, VEP, etc.)...
  38. ncbi Fractal-like image statistics in visual art: similarity to natural scenes
    Christoph Redies
    Institute of Anatomy I, School of Medicine, Friedrich Schiller University, D 07740 Jena, Germany
    Spat Vis 21:137-48. 2007
    ....
  39. ncbi Frequency domain and time complex analyses manifest low correlation and temporal variability when calculating activation rates in atrial fibrillation patients
    Angelo B Biviano
    Cardiology Division, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Pacing Clin Electrophysiol 34:540-8. 2011
    ..We report: (1) their correlation when measuring AF activation rates, (2) comparisons of recording durations required to minimize variability, and (3) differences in the temporal reproducibility...
  40. pmc High-throughput subtomogram alignment and classification by Fourier space constrained fast volumetric matching
    Min Xu
    Program in Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA
    J Struct Biol 178:152-64. 2012
    ..As a proof of principle, we can demonstrate that the automatic method can successfully classify a large number of experimental subtomograms without the need of a reference structure...
  41. ncbi Ultra-high-speed volumetric tomography of human retinal blood flow
    Tilman Schmoll
    Center of Biomedial Engineering and Physics, Medical University Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Opt Express 17:4166-76. 2009
    ..Experimental data of 3D static DFDOCT sets from fovea and nerve head region are shown together with first 4D imaging of retinal capillary flow...
  42. ncbi Sparsity based sub-wavelength imaging with partially incoherent light via quadratic compressed sensing
    Yoav Shechtman
    Department of Control Science and Engineering, Harbin Institute of Technology, Harbin 150001, China
    Opt Express 19:14807-22. 2011
    ..Specifically for microscopy, this method can be readily extended to white light microscopes with the additional knowledge of the light source spectrum...
  43. pmc Robust spectral analysis of videocapsule images acquired from celiac disease patients
    Edward J Ciaccio
    Department of Medicine Celiac Disease Center, Columbia University, New York, USA
    Biomed Eng Online 10:78. 2011
    ..Longer periodicity is related to greater image texture at areas of villous atrophy in celiac disease. However, extraneous features and spatiotemporal phase shift may mask DF rhythms...
  44. pmc Electron-induced dissociation of glycosaminoglycan tetrasaccharides
    Jeremy J Wolff
    Department of Chemistry, University of Georgia, Athens, Georgia 30602, USA
    J Am Soc Mass Spectrom 19:1449-58. 2008
    ..These data suggest that for EDD, electron detachment plays a significant role in distinguishing glucuronic acid from iduronic acid...
  45. ncbi The handaxe reloaded: a morphometric reassessment of Acheulian and Middle Paleolithic handaxes
    Radu Iovita
    Forschungsbereich Altsteinzeit, Römisch Germanisches Zentralmuseum Mainz, Schloß Monrepos, D 56567 Neuwied, Germany
    J Hum Evol 61:61-74. 2011
    ..Both standard caliper-based morphometrics and Elliptical Fourier Analysis applied to coordinate data taken from digitized images of handaxes are used to assess shape...
  46. pmc Accelerating and focusing protein-protein docking correlations using multi-dimensional rotational FFT generating functions
    David W Ritchie
    Department of Computing Science, University of Aberdeen, Aberdeen, Scotland, UK
    Bioinformatics 24:1865-73. 2008
    ..Hence there is a need to develop more powerful and more versatile FFT docking techniques...
  47. pmc Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media
    D A Berk
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston 02114
    Biophys J 65:2428-36. 1993
    A new method for the measurement of diffusion in thick samples is introduced, based upon the spatial Fourier analysis of Tsay and Jacobson (Biophys. J...
  48. ncbi On computing dominant frequency from bipolar intracardiac electrograms
    Gerald Fischer
    University for Health Sciences, Medical Informatics and Technology UMIT, Hall in Tyrol 6060, Austria
    IEEE Trans Biomed Eng 54:165-9. 2007
    ..It is the focus of this paper to provide this background by a Fourier analysis. We demonstrate that it is mainly the timing of the narrow deflections (local activation at the catheter tip) ..
  49. ncbi Technical considerations for dominant frequency analysis
    Jason Ng
    Bluhm Cardiovascular Center and the Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Cardiovasc Electrophysiol 18:757-64. 2007
    ..The aim of this study was to explore technical issues that may affect the estimation of local activation rate during AF using DF analysis...
  50. ncbi Imaging mass spectrometry: hype or hope?
    Ron M A Heeren
    FOM Institute for Atomic and Molecular Physics, Amsterdam, The Netherlands
    J Am Soc Mass Spectrom 20:1006-14. 2009
    ....
  51. pmc Evidence that localized variation in primate sequence divergence arises from an influence of nucleosome placement on DNA repair
    Hua Ying
    John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia
    Mol Biol Evol 27:637-49. 2010
    ..Our results support a role for differential DNA repair rates between open and closed chromatin in the spatial distribution of rate heterogeneity...
  52. ncbi Novel method to quantify loss of heart rate variability in pediatric multiple organ failure
    Shane M Tibby
    Department of Critical Care Medicine, Hospital for Sick Children, Toronto, Canada
    Crit Care Med 31:2059-67. 2003
    ..To develop a power-law model for measurement of heart rate variability (HRV) and to compare this model with established methods for measuring HRV in a group of children with organ failure (OF)...
  53. ncbi Comparison of STFT and wavelet transform methods in determining epileptic seizure activity in EEG signals for real-time application
    M Kemal Kiymik
    Department of Electric and Electronic Engineering, Kahramanmaras Sutcu Imam University, 46100 Kahramanmaras, Turkey
    Comput Biol Med 35:603-16. 2005
    ..However, the CWT still had good resolution and performance high enough for use in clinical and research settings...
  54. pmc Drift-free position estimation of periodic or quasi-periodic motion using inertial sensors
    Win Tun Latt
    Hamlyn Centre for Robotic Surgery, and Department of Computing, Imperial College London, London, UK
    Sensors (Basel) 11:5931-51. 2011
    ..Results demonstrate that the performance of the proposed method outperforms the existing analytical integration method...
  55. ncbi Narrow peaks and high dimensionalities: exploiting the advantages of random sampling
    Krzysztof Kazimierczuk
    Department of Chemistry, University of Warsaw, Warszawa, Poland
    J Magn Reson 197:219-28. 2009
    ..We present the example of such approach, referred to as Sparse Multidimensional Fourier Transform...
  56. ncbi Left atrial dilatation resulting from chronic mitral regurgitation decreases spatiotemporal organization of atrial fibrillation in left atrium
    Thomas H Everett
    Cardiovascular Research Institute and Division of Cardiology, University of California San Francisco, 500 Parnassus Avenue, MU East 4, San Francisco, CA 94143 1354, USA
    Am J Physiol Heart Circ Physiol 286:H2452-60. 2004
    ..In addition, there was a decrease in OI and in the correlation coefficients in the LA of the MR model. These results suggest that the AF substrate in the MR model may be different from that of control or RAP models...
  57. ncbi Stable microreentrant sources as a mechanism of atrial fibrillation in the isolated sheep heart
    R Mandapati
    Department of Pharmacology, SUNY Health Science Center, Syracuse, NY 13210, USA
    Circulation 101:194-9. 2000
    ..Our objective was to use a combination of optical and bipolar electrode recordings to identify sites of periodic activity during AF and elucidate their mechanism...
  58. ncbi An accurate mass tag strategy for quantitative and high-throughput proteome measurements
    Richard D Smith
    Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Proteomics 2:513-23. 2002
    ..Using this strategy, in our first application we have been able to identify AMTs for >60% of the potentially expressed proteins in the organism Deinococcus radiodurans...
  59. ncbi Epicardial mapping of chronic atrial fibrillation in patients: preliminary observations
    Jayakumar Sahadevan
    Department of Medicine, Division of Cardiology, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, The Louis B Stokes Veterans Administration Medical Center, Cleveland, Ohio 44106, USA
    Circulation 110:3293-9. 2004
    ....
  60. ncbi Comparison of detrending methods for optimal fMRI preprocessing
    Jody Tanabe
    Department of Radiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Neuroimage 15:902-7. 2002
    ..However, auto-detrending (selecting the best algorithm or none, if detrending is not useful) appears to be the most judicious choice, particularly for analyzing fMRI data with weak activations in the presence of baseline drift...
  61. ncbi Fourier analysis of induced irregular astigmatism. Photorefractive keratectomy versus laser in situ keratomileusis in a bilateral cohort of hyperopic patients
    Andrea Sciscio
    Department of Ophthalmology, St Thomas Hospital, London, England, United Kingdom
    J Cataract Refract Surg 29:1709-17. 2003
    To analyze corneal topographic data by Fourier analysis to determine differences in irregular astigmatism following spherical hyperopic correction by photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK).
  62. ncbi Scaling behaviour of heartbeat intervals obtained by wavelet-based time-series analysis
    P C Ivanov
    Center for Polymer Studies, Boston University, Massachusetts 02215, USA
    Nature 383:323-7. 1996
    ..The approach introduced here should be useful in the analysis of other nonstationary biological signals...
  63. ncbi Label-free protein quantification using LC-coupled ion trap or FT mass spectrometry: Reproducibility, linearity, and application with complex proteomes
    Guanghui Wang
    Proteomics Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Proteome Res 5:1214-23. 2006
    ..The utility of this method to biomarker discovery is likely to synergize with future improvements in the detecting sensitivity of mass spectrometers...
  64. pmc Identification of SYWKQCAFNAVSCFamide: a broadly conserved crustacean C-type allatostatin-like peptide with both neuromodulatory and cardioactive properties
    Patsy S Dickinson
    Department of Biology, Bowdoin College, Brunswick, ME 04011, USA
    J Exp Biol 212:1140-52. 2009
    ..In H. americanus, SYWKQCAFNAVSCFamide is capable of modulating the output of both the pyloric circuit of the stomatogastric nervous system and the heart. This is the first demonstration of bioactivity for this peptide in any species...
  65. ncbi Spectral analysis of ventricular fibrillation and closed-chest cardiopulmonary resuscitation
    H U Strohmenger
    Department of Anesthesiology and Critical Care Medicine, University of Ulm, Germany
    Resuscitation 33:155-61. 1996
    ..In this model after elimination of oscillations due to mechanical CPR, median fibrillation frequency best reflects the probability of resuscitation success...
  66. ncbi Traction fields, moments, and strain energy that cells exert on their surroundings
    James P Butler
    Physiology Program, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Physiol Cell Physiol 282:C595-605. 2002
    ..Finally, we give explicit formulas for reducing the traction and displacement fields to contraction moments, the orientation of the principal axes of traction, and the strain energy imparted by the cell to the substrate...
  67. ncbi Exploring artificial cranial deformation using elliptic Fourier analysis of Procrustes aligned outlines
    Martin Friess
    New York Consortium in Evolutionary Primatology, American Museum of Natural History, New York, NY 10024, USA
    Am J Phys Anthropol 122:11-22. 2003
    ..The present study compares samples of intentionally deformed and undeformed human crania, using elliptic Fourier analysis (EFA), a morphometric approach which has been shown to be particularly appropriate for characterizing the ..
  68. pmc Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability
    F Xavier Castellanos
    Institute for Pediatric Neuroscience, New York University, Child Study Center, NYU School of Medicine, New York, New York 10016, USA
    Biol Psychiatry 57:1416-23. 2005
    ..These results highlight the importance of retaining time-series data and quantitatively examining intra-subject measures of variability as a putative endophenotype for ADHD...
  69. pmc Analysis of E. coli K5 capsular polysaccharide heparosan
    Mellisa Ly
    Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, 110 Eight Street, Troy, NY 12180, USA
    Anal Bioanal Chem 399:737-45. 2011
    ..Unbleached and bleached heparosan produced by fermentation of E. coli K5 had similar number-averaged MWs (M(N)), weight-averaged MWs (M(W)), and MW ranges of 3,000 to 150,000 Da...
  70. ncbi Understanding and interpreting dominant frequency analysis of AF electrograms
    Jason Ng
    Bluhm Cardiovascular Center and the Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Cardiovasc Electrophysiol 18:680-5. 2007
    ..This will in turn allow the strengths and limitations of dominant frequency analysis to be better understood and improve its applicability to potential clinical usages...
  71. ncbi Automated ambient desorption-ionization platform for surface imaging integrated with a commercial Fourier transform ion cyclotron resonance mass spectrometer
    Jaroslav Pól
    Laboratory of Molecular Structure Characterization, Institute of Microbiology, Academy of Sciences of the Czech Republic, CZ 142 20 Prague, Czech Republic
    Anal Chem 81:8479-87. 2009
    ..It showed promise in imaging of phytocompounds from plant leaves, and selective ionization of a sterol lipid was achieved by DAPPI from a brain tissue sample...
  72. ncbi Morphometry of dermal collagen orientation by Fourier analysis is superior to multi-observer assessment
    Paul P M van Zuijlen
    Burns Centre, Red Cross Hospital, Beverwijk, The Netherlands
    J Pathol 198:284-91. 2002
    ..The hypothesis on which this study is based is that an objective image analysis technique, Fourier analysis, would improve the reliability (are the measurements reproducible?) and the accuracy (does the method measure ..
  73. ncbi Fourier analysis of optical coherence tomography and scanning laser polarimetry retinal nerve fiber layer measurements in the diagnosis of glaucoma
    Edward A Essock
    Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY 40292, USA
    Arch Ophthalmol 121:1238-45. 2003
    ..To evaluate a new Fourier-based analysis method for diagnosing glaucoma using retinal nerve fiber layer (RNFL) thickness estimates obtained from the optical coherence tomograph (OCT) (OCT 2000) and the scanning laser polarimeter (GDx)...
  74. ncbi Optimized grid-based protein-protein docking as a global search tool followed by incorporating experimentally derivable restraints
    Wei Huang
    School of Life Sciences and Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China USTC, Hefei, Anhui 230027, People s Republic of China
    Proteins 80:691-702. 2012
    ....
  75. ncbi Clustering of change patterns using Fourier coefficients
    Jaehee Kim
    Department of Statistics, Duksung Women s University, Seoul National University, Seoul, S Korea
    Bioinformatics 24:184-91. 2008
    ..In addition, as their limiting distribution is a multivariate normal, a model-based clustering method incorporating statistical properties would be appropriate...
  76. pmc Cardiac magnetic resonance assessment of dyssynchrony and myocardial scar predicts function class improvement following cardiac resynchronization therapy
    Kenneth C Bilchick
    Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    JACC Cardiovasc Imaging 1:561-8. 2008
    ....
  77. ncbi Description of joint movements in human and non-human primate locomotion using Fourier analysis
    David Webb
    Department of Anthropology and Sociology, Kutztown University, Kutztown, PA 19530, USA
    Primates 48:277-92. 2007
    To describe and help interpret joint movements in various forms of primate locomotion, we explored the use of Fourier analysis to represent changing joint angles as a series of sine and cosine curves added together to approximate the raw ..
  78. pmc Fourier analysis of STimulated echoes (FAST) for the quantitative analysis of left ventricular twist
    Meral Reyhan
    Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA
    J Magn Reson Imaging 35:587-93. 2012
    ..To validate a novel method for the rapid and facile quantification of left ventricular (LV) twist from tagged magnetic resonance images and demonstrate the potential clinical utility in a series of 20 healthy volunteers...
  79. ncbi Assessment of global atrial fibrillation organization to optimize timing of atrial defibrillation
    T H Everett
    Cardiovascular Division, Department of Internal Medicine, The University of Virginia Health System, Charlottesville, VA 22908, USA
    Circulation 103:2857-61. 2001
    ..5. CONCLUSIONS: AF signals show a high degree of variability. Shock efficacy is increased when shocks are delivered during periods of high AF organization as determined by the OI method...
  80. ncbi OMWSA: detection of DNA repeats using moving window spectral analysis
    Liping Du
    Department of Electronic Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Bioinformatics 23:631-3. 2007
    ..AVAILABILITY: Available on http://www.hy8.com/~tec/sw01/omwsa01.zip. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online...
  81. pmc Quantitative assessment of systolic and diastolic left ventricular twist using Fourier Analysis of Stimulated echoes (FAST) and CSPAMM
    Meral Reyhan
    Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California 90095 7206, USA
    J Magn Reson Imaging 37:678-83. 2013
    To evaluate Fourier Analysis of Stimulated echoes (FAST) and CSPAMM for the quantification of left ventricular (LV) systolic and diastolic function and compare it with the previously validated FAST+SPAMM technique.
  82. ncbi Fourier analysis of intracranial aneurysms: towards an objective and quantitative evaluation of the shape of aneurysms
    Stefan Rohde
    Institut für Neuroradiologie, Klinikum der Johann Wolfgang Goethe Universitat, Schleusenweg 2 16, 60528 Frankfurt am Main, Germany
    Neuroradiology 47:121-6. 2005
    ..To quantify morphological differences, Fourier analysis of the shape of intracranial aneurysms was introduced...
  83. ncbi A fourier analysis of the dose grid resolution required for accurate IMRT fluence map optimization
    James F Dempsey
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610 0385, USA
    Med Phys 32:380-8. 2005
    ..An information theory based Fourier analysis of the accuracy of discrete representations of three-dimensional dose distributions is presented...
  84. pmc F2Dock: fast Fourier protein-protein docking
    Chandrajit Bajaj
    Computational Visualization Center, Department of Computer Sciences and the Institute of Computational Engineering and Sciences, University of Texas at Austin, 1 University Station C0500, Austin, Texas 78712, USA
    IEEE/ACM Trans Comput Biol Bioinform 8:45-58. 2011
    ....
  85. pmc A new transform for the analysis of complex fractionated atrial electrograms
    Edward J Ciaccio
    Department of Medicine, Division of Cardiology, Columbia University, USA
    Biomed Eng Online 10:35. 2011
    Representation of independent biophysical sources using Fourier analysis can be inefficient because the basis is sinusoidal and general...
  86. doi Low-frequency Fourier analysis of speech rhythm
    Sam Tilsen
    J Acoust Soc Am 124:EL34-9. 2008
    A method for studying speech rhythm is presented, using Fourier analysis of the amplitude envelope of bandpass-filtered speech...
  87. pmc Optical clearing for improved contrast in second harmonic generation imaging of skeletal muscle
    Sergey Plotnikov
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Biophys J 90:328-39. 2006
    ..SHG and optical clearing may provide an ideal mechanism to study physiology in highly scattering skeletal or cardiac muscle tissue with significantly improved depth of penetration and achievable imaging depth...
  88. ncbi Discrete Fourier analysis of ultrasound RF time series for detection of prostate cancer
    M Moradi
    School of Computing, Queen s University, Kingston, ON, K7L 3N6, Canada
    Conf Proc IEEE Eng Med Biol Soc 2007:1339-42. 2007
    ..03 cm2. Based on pathology results used as gold standard, we have acquired mean accuracy of 91%, mean sensitivity of 92% and mean specificity of 90% on seven human prostates...
  89. pmc Measurement of total blood flow in the normal human retina using Doppler Fourier-domain optical coherence tomography
    Y Wang
    Center for Ophthalmic Optics and Lasers, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Br J Ophthalmol 93:634-7. 2009
    ..To measure total retinal blood flow in normal human eyes using Doppler Fourier-domain optical coherence tomography (FD-OCT)...
  90. ncbi Adaptive cyclic physiologic noise modeling and correction in functional MRI
    Erik B Beall
    Imaging Institute, Cleveland Clinic, 9500 Euclid Ave U15, Cleveland, OH, USA
    J Neurosci Methods 187:216-28. 2010
    ..Our results demonstrate a significant improvement in the sensitivity of fMRI (up to a 17% increase in activation volume for fMRI compared with higher order traditional noise correction) and functional connectivity analyses...
  91. ncbi Identification of sites of ubiquitination in proteins: a fourier transform ion cyclotron resonance mass spectrometry approach
    Helen J Cooper
    School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Anal Chem 76:6982-8. 2004
    ..Assignments were confirmed by AI ECD or IRMPD. The Gly-Gly modification is stable and both tandem mass spectrometric techniques are suitable, providing extensive sequence coverage and retention of the modification on backbone fragments...
  92. ncbi Synthetic aperture fourier holographic optical microscopy
    Sergey A Alexandrov
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, WA, Australia
    Phys Rev Lett 97:168102. 2006
    ....
  93. ncbi Fourier analysis reveals increased trabecular spacing in sickle cell anemia
    T D Faber
    Section of Oral and Maxillofacial Radiology, UCLA School of Dentistry, Los Angeles, CA 90095 1668, USA
    J Dent Res 81:214-8. 2002
    Sickle cell anemia may expand marrow spaces in the jaws. Fourier analysis is well-suited to the analysis of trabecular spacing in radiographs...
  94. pmc GPU.proton.DOCK: Genuine Protein Ultrafast proton equilibria consistent DOCKing
    Alexander A Kantardjiev
    Biophysical Chemistry Group, Institute of Organic Chemistry, Bulgarian Academy of Sciences, and Department of Physics, Sofia University, Sofia, Bulgaria
    Nucleic Acids Res 39:W223-8. 2011
    ..The output is comprised of docked complexes in PDB format as well as interactive visualization in a molecular viewer. GPU.proton.DOCK server can be accessed at http://gpudock.orgchm.bas.bg/...
  95. pmc Improved frequency resolution for characterization of complex fractionated atrial electrograms
    Edward J Ciaccio
    Department of Medicine, Division of Cardiology, Columbia University Medical Center, New York, NY, USA
    Biomed Eng Online 11:17. 2012
    ..Herein the spectral resolution of a recently described and relatively new spectral estimation technique is compared to the Fourier radix-2 implementation...
  96. ncbi In vitro validation of new Fourier-domain optical coherence tomography
    Satoko Tahara
    Harrington McLaughlin Heart and Vascular Institute, University Hospitals Case Medical Center, and Case Western Reserve University, Cleveland, OH 44106 5038, USA
    EuroIntervention 6:875-82. 2011
    ..To validate the accuracy and evaluate the intra- and inter-observer variability of vascular measurements using novel Fourier-domain optical coherence tomography (FD-OCT) versus intravascular ultrasound (IVUS) in a coronary phantom model...
  97. ncbi Dynamic PET reconstruction using wavelet regularization with adapted basis functions
    Jeroen Verhaeghe
    Department of Electronics and Information Systems, MEDISIP, Ghent University IBBT IBiTech, De Pintelaan 185 block B, B 9000 Ghent, Belgium
    IEEE Trans Med Imaging 27:943-59. 2008
    ....
  98. pmc Generic real-time uniform K-space sampling method for high-speed swept-source optical coherence tomography
    Jiefeng Xi
    Department of Biomedical Engineering, Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Opt Express 18:9511-7. 2010
    ..Real-time imaging of biological tissues using such a system was demonstrated with a measured axial resolution of 9.3 mum and detection sensitivity greater than 120dB...
  99. ncbi Frequency analysis of atrial fibrillation surface and intracardiac electrograms during pulmonary vein isolation
    Inaki Romero
    Physikalisch Technische Bundesanstalt, Berlin, Germany
    Europace 13:1340-5. 2011
    ..This work explores the fibrillatory frequency properties of both surface and intracardiac electrograms before and after pulmonary vein isolation (PVI) using three time-frequency techniques...
  100. ncbi Use of fast fourier transform analysis of atrial electrograms for rapid characterization of atrial activation-implications for delineating possible mechanisms of atrial tachyarrhythmias
    Kyungmoo Ryu
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA
    J Cardiovasc Electrophysiol 17:198-206. 2006
    ....
  101. ncbi Elliptical fourier analysis of symphyseal shape in great ape mandibles
    D J Daegling
    Department of Basic Medical Sciences, California College of Podiatric Medicine, 1210 Scott Street, San Francisco, CA 94115, USA
    J Hum Evol 39:107-22. 2000
    ..In this study, a type of Fourier analysis is applied to cross-sectional contours of ape mandibles in order to provide a mathematical accounting of ..

Research Grants64

  1. Mechanics of Inner Ear Hair Bundles
    KIRIAKI DOMENICA KARAVITAKI; Fiscal Year: 2012
    ..The motion will be observed using a two photon microscope and DIC optics and quantified by applying Fourier analysis on the captured images...
  2. Placental shape features, gestational timing and maternal and infant health
    Carolyn M Salafia; Fiscal Year: 2011
    ..proposes to optimize models of whole placental shape based on well-established methodologies in mathematics (Fourier analysis) and physics (statistical thermodynamics) that are based on data derived from digital images of the placental ..
  3. FIBER CELL JUNCTIONS IN NORMAL AND CATARACTOUS LENSES
    M Joseph Costello; Fiscal Year: 2011
    ..b>Fourier analysis was used to relate the amount of texturing to the observed opacification of the nucleus...
  4. IMMUNOGLOBULINS IN MULTIPLE MYELOMA & AMYLOIDOSIS
    Allen Edmundson; Fiscal Year: 1993
    ..The detailed modes of binding of these ligands will continue to be determined by difference Fourier analysis at 2.7-A resolution, in combination with interactive computer graphics...
  5. A NEW METHOD FOR ANALYSIS OF CORONARY ARTERY BEHAVIOR
    Thomas Williams; Fiscal Year: 1980
    It is the objective of this study to test the usefulness of a rigorous analytical technique (Fourier Analysis) for the characterization of the physical state of the coronary arterial bed...
  6. Quantifying Left Ventricular Ejection Effectiveness
    Michael Pinsky; Fiscal Year: 2007
    ..a novel application of the assessment of LV ejection efficiency combining regional phase angle analysis with Fourier analysis of both phase angle and amplitude dispersion from echocardiographic data...
  7. Surgical Monitor for Detection of Spinal Cord Injury
    ANANTH NATARAJAN; Fiscal Year: 2003
    ..In our Phase I effort, we will use adaptive Fourier analysis of SSEPs to evaluate parametric changes in the signal, and correlate the results with injury...
  8. ANALYSIS OF FLICKER RETINAL ACTION POTENTIALS
    ROBERT DE VOE; Fiscal Year: 1990
    ..motion detection better, the periodic responses elicited by these sequential stimuli will be compared, using Fourier analysis, with flicker responses to simultaneous periodic stimuli...
  9. INTRAORAL PRESSURE VARIATIONS--THE PALATAL MICROPHONE
    JOHN SEIKEL; Fiscal Year: 1992
    ..Static estimation of tract resonances will be made through Fourier analysis, with resonant peaks identified and graphically represented in spatiotopic order...
  10. TRANSMISSION ELECTRON MICROSCOPE--PHILIPS CM120
    M Costello; Fiscal Year: 1999
    ..resolution bottom mount CCD digital camera accessory would permit collection of digitized images for on-line Fourier analysis, computerized tomography, automatic montaging, low/minimum dose imaging and production of publication quality ..
  11. FUNCTIONAL DESCRIPTION OF VISUAL MECHANISMS
    D Snodderly; Fiscal Year: 1980
    ..Contrast sensitivities will be determined using sinusoidal grating patterns and Fourier analysis. Effects of mean luminance level and temporal transients will be investigated...
  12. Bi-Plane Correlation Imaging: Detection of Lung Cancer
    Ehsan Samei; Fiscal Year: 2007
    ..The findings will be used to substantiate the capability of BCI for improving the early detection of lung nodules and to optimize its performance on actual clinical cases. ..
  13. Resolution requirements for mammographic displays
    Ehsan Samei; Fiscal Year: 2004
    ..The results will be used to formulate recommendations to the breast imaging community concerning display resolution criteria for safe and optimized soft-copy display of digital mammograms. ..
  14. Early Detection of Lung Cancer via Bi Plane Correlation
    Ehsan Samei; Fiscal Year: 2002
    ..The findings will be used to demonstrate the capability of the approach for improving the detection of lung nodules, and thus the prognosis of lung cancer. ..
  15. Mathematical and Statistical Models for Nucleosome
    Ji Ping Wang; Fiscal Year: 2010
    ..5) Automate the developed tools and algorithms. ..
  16. Multi-Resolution Corneal Topography (MRCT)
    EDWIN SARVER; Fiscal Year: 2006
    ..research grant ..
  17. Scanning Ocular Aberration Measurement (SAM) System
    EDWIN SARVER; Fiscal Year: 2007
    ..In addition, the ability to measure these aberrations dynamically while the eye is changing focus from a distant to a near object will be provided. [unreadable] [unreadable] [unreadable] [unreadable]..
  18. National Assessment of the Mortality and Morbidity Effects of Tropospheric Ozone
    Michelle L Bell; Fiscal Year: 2010
    ..The goal of this work is to provide policy-makers, scientists, and the public with a better understanding of how ozone affects health in order to aid more effective decisions regarding protection of human health. ..
  19. LOCALIZATION OF SOUND BY HUMAN LISTENERS
    William Hartmann; Fiscal Year: 2008
    ..at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description, ..
  20. Real-Time MRI and 3D Modeling: Development and Application to Patellofemoral Pain
    GARRY GOLD; Fiscal Year: 2008
    ..The novel imaging and biomechanical modeling techniques developed in this research will be used to improve the diagnosis and treatment of a range of musculoskeletal disorders. ..
  21. EPR Sample-cell-Resonator Design and Construction
    James Hyde; Fiscal Year: 2008
    ..Work proposed here will improve the quality of data obtained in these experiments. [unreadable] [unreadable] [unreadable]..
  22. Visual Dysfunction in Retinal Degenerations
    Kenneth R Alexander; Fiscal Year: 2010
    ....
  23. LOOP GAP RESONATOR COILS FOR MRI AND 31P SPECTROSCOPY
    James Hyde; Fiscal Year: 2001
    ..The research proposed here is in support of these four streams of fMRI research. ..
  24. Subjective Refraction by Meridional Power Matching
    EDWIN SARVER; Fiscal Year: 2002
    ..Technological Innovation: Providing an accurate, low-cost, low-maintenance refractor that can be easily transported and used in hostile environments. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
  25. DEVELOPMENT OF BIOMEDICAL ESR INSTRUMENTATION
    James Hyde; Fiscal Year: 2002
    ..The investigator asserts that only on such a foundation can a rational approach to improved human health be based. ..
  26. BROADBAND EPR SPECTROMETER WITH DIGITAL SUBSAMPLING
    James Hyde; Fiscal Year: 2002
    ..It is the only method that can detect the formation of free radicals in biology unambiguously. It contributes to health-related research at the basic fundamental level. ..
  27. 3T Whole-Body MRI Scanner for Functional Imaging
    James Hyde; Fiscal Year: 2003
    ..It will have no clinical fee-for-service usage. The fMRI group at MCW is superbly positioned to provide leadership at a national level in the use of fMRI in medicine. ..
  28. BROADBAND EPR SPECTROMETER WITH DIGITAL SUBSAMPLING
    James Hyde; Fiscal Year: 2003
    ..It is the only method that can detect the formation of free radicals in biology unambiguously. It contributes to health-related research at the basic fundamental level. ..
  29. Breast Cancer Imaging Using a Solid-State SPECT Camera
    G Zeng; Fiscal Year: 2005
    ..abstract_text> ..
  30. In vivo Thermoacoustic Imaging of HER2 Status
    Robert Kruger; Fiscal Year: 2008
    ..3. Determine the minimum detectable concentration of IRIS Green One dye that can be detected within a 1.2-mm diameter tube in a breast-tissue mimicking phantom. ..
  31. Neurobehavioral Consequences of Adolescent Alcohol
    Cindy Ehlers; Fiscal Year: 2008
    ..AIM 3: To investigate the neurochemical substrates underlying the lasting neurobehavioral consequences of adolescent ethanol exposure, with a focus on NMDA systems ..
  32. INTERACTIONS BETWEEN PERCEPTUAL AND CONCEPTUAL LEARNING
    Robert Goldstone; Fiscal Year: 2002
    ..abstract_text> ..
  33. OPTICAL TOMOGRAPHY FOR THE DIAGNOSIS OF JOINT DISEASES
    ANDREAS HIELSCHER; Fiscal Year: 2007
    ..The ultimate goal of this proposal is to lay the groundwork for a clinical viable joint imager that can be used in a phase II clinical trial in i subsequent studies. ..
  34. Ultra High Field (16.4 Tesla) Animal MRI/MRS System
    Michael Garwood; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  35. Neurobehavioral Control of Body Fluid Balance in Mouse
    Alan Johnson; Fiscal Year: 2009
    ..heat) challenges. These studies will be especially important for understanding mechanisms underlying pathological conditions such as hypertension and congestive heart failure where excess thirst and sodium intake have been documented. ..
  36. Structural Mapping of Protein Complexes by Hydrogen/Deuterium Exchange
    Alan Marshall; Fiscal Year: 2009
    ..This project is multidisiplinary and pulls together several distinguished collaborators with focused research projects that will benefit directly from H/D exchange with high-resolution mass analysis. ..
  37. PROTEIN STRUCTURE BY ANALYSIS OF SPIN LABEL INTERACTIONS
    ERIC HUSTEDT; Fiscal Year: 2002
    ..abstract_text> ..
  38. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry N Thibos; Fiscal Year: 2010
    ..Project 6. Develop a new concept of wavefront tomography to characterize the 3-dimensional structure of the eye's optical system from a series of wavefront measurements along multiple lines-of-sight. ..
  39. Conference: Diffraction Methods in Structural Biology
    Michael Chapman; Fiscal Year: 2002
    ..Junior participation will be encouraged with a new policy of 3 mini-talks each day invited from the poster-presentations by the day's session chairs. ..
  40. Hierarchical Methods for Large BioMolecular Complexes
    Chandrajit L Bajaj; Fiscal Year: 2010
    ..AIM 4: To implement, test, package and freely distribute our structural feature determination and fast search/fitting techniques. ..
  41. Protein Structure by EPR Distance Determination and Molecular Modeling
    ERIC HUSTEDT; Fiscal Year: 2007
    ..In general, the tools developed in this proposal will be applicable to a wide range of SDSL studies of protein structure, assembly, and functional dynamics in laboratories worldwide. [unreadable] [unreadable] [unreadable]..
  42. Image Reconstruction with Solid Srate SPECR
    LAWRENCE ZENG; Fiscal Year: 2005
    ..abstract_text> ..
  43. Role of Parabrachial 5-HT in Thirst and Salt Appetite
    Alan Johnson; Fiscal Year: 2005
    ..g., hypertension; congestive heart failure; renal disease). ..
  44. Decoupling of Principal Renal Autoregulatory Mechanisms
    Ki Chon; Fiscal Year: 2005
    ..By exercising this model, as described under Specific Aim (5), we plan to begin understanding the underlying reasons for the changes observed in autoregulation under pathological conditions. ..
  45. RISK FACTORS FOR ALCOHOLISM IN NATIVE AMERICANS
    Cindy Ehlers; Fiscal Year: 2006
    ..The identification of such variables may potentially be useful in the development of specific prevention and treatment programs for this population as well as other Native American tribes. ..
  46. WORKING MEMORY IN OBSTRUCTIVE SLEEP APNEA-AN fMRI STUDY
    Robert Thomas; Fiscal Year: 2006
    ..abstract_text> ..
  47. Sensory Processing Deficits in Cannabis Use
    PATRICK SKOSNIK; Fiscal Year: 2006
    ..Taken together, this data may serve to elucidate whether the known cognitive dysfunction observed in cannabis use is in part related to disturbances in early sensory information processing and/or neural synchronization. ..
  48. CT DEVICE FOR MICROIMAGING OF TISSUE SPECIMENS IN VIVO
    Felix Wehrli; Fiscal Year: 2001
    ..abstract_text> ..
  49. Effect of Bracing and Strengthening Exercises on Posterior Tibial Tendon Dysfunct
    Jeff Houck; Fiscal Year: 2007
    ..g. infection) there is a clear benefit to the individual and society. [unreadable] [unreadable]..
  50. Enhancing Duke University's Animal Resources
    John Norton; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  51. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2004
    ....
  52. PHASE RESETTING AND SENSORY INHIBITION IN THE CNS
    Nashaat Boutros; Fiscal Year: 2005
    ....
  53. Long-range processing in dorsal-occipital cortex
    Christopher Tyler; Fiscal Year: 2005
    ..The final project will introduce a clinical component, quantifying symmetry-blindness in neurological patients with relevant lesions, together with comparison studies in matched controls. ..
  54. TRANSITION TO NIPPLE FEEDING FOR PRETERM INFANTS
    Gail McCain; Fiscal Year: 2008
    ..Parental reports about their infants' feeding problems at 3 months post hospital discharge will be content analyzed. [unreadable] [unreadable] [unreadable]..
  55. MRI-Compatible Diffuse Optical Tomography System
    ANDREAS HIELSCHER; Fiscal Year: 2005
    ..This comparison will quantify the advantages and disadvantages of these different optical imaging modalities. ..
  56. Simultaneous MEG and ULF MRI for Functional Imaging
    Robert Kraus; Fiscal Year: 2009
    ..ULF-MRI that may lead to direct imaging of neural activity, even with modest temporal resolution, can be used to constrain the simultaneously acquired MEG signal, providing millisecond or better temporal resolution. ..
  57. Shear-mode Transcranial Ultrasound Imaging
    Gregory Clement; Fiscal Year: 2005
    ..It could potentially offer a non-ionizing imaging method that could in operate clinically, while introducing a new technique into medical and biological imaging. ..
  58. Structure of the Human Cortical Depth Map
    Christopher Tyler; Fiscal Year: 2004
    ..The mapping results will be validated by functional studies of the susceptibility of each cortical area to depth variations and of the time course depth adaptation, and also for insensitivity to contrast variations. ..
  59. Signal processing software for biomolecular NMR
    Jeffrey Hoch; Fiscal Year: 2008
    ..The application of modern spectrum analysis in biomolecular NMR will enable the full potential of modern magnets, probes, and pulse sequences to be realized for solving challenging problems in structural biology. ..
  60. Experimental Analysis of Advanced Radiotherapy Dosimetry
    JAMES DEMPSEY; Fiscal Year: 2007
    ..Results from this work will provide a paradigm for closing the loop between the clinical treatment planning system and the MLC IMRT delivery system. ..
  61. Visual Processing in Schizophrenia and SPD
    BRIAN O DONNELL; Fiscal Year: 2009
    ..These findings may identify neurobehavioral deficits common to SZ and SPD, as well as features which differentiate these disorders. ..
  62. Human Brain Metabolism in Ketosis
    Jullie Pan; Fiscal Year: 2004
    ..We anticipate that these data will contribute towards better understanding of themechanism of seizure control by theketogenic diet. ..
  63. BIOPHYSICAL STUDY OF ANTIPSYCHOTICS BEHAVIORAL EFFECTS
    Stephen Fowler; Fiscal Year: 2009
    ..The results will improve our understanding of the pharmacological basis of dopamine related behaviors and assist in the discovery of improved antipsychotic medications. ..