finite element analysis

Summary

Summary: A computer based method of simulating or analyzing the behavior of structures or components.

Top Publications

  1. ncbi Cranial design and function in a large theropod dinosaur
    E J Rayfield
    Department of Earth Sciences, University of Cambridge, UK
    Nature 409:1033-7. 2001
  2. ncbi Dynamic finite element knee simulation for evaluation of knee replacement mechanics
    Mark A Baldwin
    Computational Biomechanics Lab, University of Denver, Denver, CO 80208, USA
    J Biomech 45:474-83. 2012
  3. ncbi Simulation of a knee joint replacement during a gait cycle using explicit finite element analysis
    A C Godest
    Bioengineering Science Research Group, School of Engineering Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, UK
    J Biomech 35:267-75. 2002
  4. ncbi A human knee joint model considering fluid pressure and fiber orientation in cartilages and menisci
    K B Gu
    Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, Canada T2N 1N4
    Med Eng Phys 33:497-503. 2011
  5. ncbi Effect of superficial collagen patterns and fibrillation of femoral articular cartilage on knee joint mechanics-a 3D finite element analysis
    M E Mononen
    Department of Applied Physics, University of Eastern Finland, POB 1627, FI 70211 Kuopio, Finland
    J Biomech 45:579-87. 2012
  6. ncbi Toward integration of geometric morphometrics and computational biomechanics: new methods for 3D virtual reconstruction and quantitative analysis of Finite Element Models
    W C H Parr
    School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    J Theor Biol 301:1-14. 2012
  7. pmc Prediction of new clinical vertebral fractures in elderly men using finite element analysis of CT scans
    Xiang Wang
    Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA
    J Bone Miner Res 27:808-16. 2012
  8. ncbi Efficient 3D finite element analysis of dental restorative procedures using micro-CT data
    Pascal Magne
    University of Southern California, Division of Primary Oral Health Care, School of Dentistry, 925 West 34th Street, DEN 4366, Los Angeles, CA 90089 0641, USA
    Dent Mater 23:539-48. 2007
  9. pmc Using occlusal wear information and finite element analysis to investigate stress distributions in human molars
    Stefano Benazzi
    Department of Anthropology, University of Vienna, Vienna, Austria
    J Anat 219:259-72. 2011
  10. ncbi Creep behavior of the intact and meniscectomy knee joints
    M Kazemi
    Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, Canada T2N 1N4
    J Mech Behav Biomed Mater 4:1351-8. 2011

Detail Information

Publications369 found, 100 shown here

  1. ncbi Cranial design and function in a large theropod dinosaur
    E J Rayfield
    Department of Earth Sciences, University of Cambridge, UK
    Nature 409:1033-7. 2001
    b>Finite element analysis (FEA) is used by industrial designers and biomechanicists to estimate the performance of engineered structures or human skeletal and soft tissues subjected to varying regimes of stress and strain...
  2. ncbi Dynamic finite element knee simulation for evaluation of knee replacement mechanics
    Mark A Baldwin
    Computational Biomechanics Lab, University of Denver, Denver, CO 80208, USA
    J Biomech 45:474-83. 2012
    ..8 mm and 2.2° for PF and TF translations and rotations. The whole joint FE simulator described in this study can be applied to investigate a wide range of clinical and research questions...
  3. ncbi Simulation of a knee joint replacement during a gait cycle using explicit finite element analysis
    A C Godest
    Bioengineering Science Research Group, School of Engineering Sciences, University of Southampton, Highfield, Southampton SO17 1BJ, UK
    J Biomech 35:267-75. 2002
    ..Implicit finite element analysis techniques have been used previously to examine the polyethylene stresses...
  4. ncbi A human knee joint model considering fluid pressure and fiber orientation in cartilages and menisci
    K B Gu
    Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, Canada T2N 1N4
    Med Eng Phys 33:497-503. 2011
    ..human knee models, and thus the fluid-flow dependent response of the knee has not been explored using finite element analysis. In the present study, the fluid pressure and site-specific collagen fiber orientation in the cartilages ..
  5. ncbi Effect of superficial collagen patterns and fibrillation of femoral articular cartilage on knee joint mechanics-a 3D finite element analysis
    M E Mononen
    Department of Applied Physics, University of Eastern Finland, POB 1627, FI 70211 Kuopio, Finland
    J Biomech 45:579-87. 2012
    ..This study provides further evidence on the importance of the collagen fibril organization for the optimal function of articular cartilage...
  6. ncbi Toward integration of geometric morphometrics and computational biomechanics: new methods for 3D virtual reconstruction and quantitative analysis of Finite Element Models
    W C H Parr
    School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, NSW 2052, Australia
    J Theor Biol 301:1-14. 2012
    ..One of the most challenging of these applications is Finite Element Analysis (FEA), a potentially powerful non-destructive tool in the prediction of mechanical behaviour...
  7. pmc Prediction of new clinical vertebral fractures in elderly men using finite element analysis of CT scans
    Xiang Wang
    Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA
    J Bone Miner Res 27:808-16. 2012
    Vertebral strength, as estimated by finite element analysis of computed tomography (CT) scans, has not yet been compared against areal bone mineral density (BMD) by dual-energy X-ray absorptiometry (DXA) for prospectively assessing the ..
  8. ncbi Efficient 3D finite element analysis of dental restorative procedures using micro-CT data
    Pascal Magne
    University of Southern California, Division of Primary Oral Health Care, School of Dentistry, 925 West 34th Street, DEN 4366, Los Angeles, CA 90089 0641, USA
    Dent Mater 23:539-48. 2007
    ..This investigation describes a rapid method for the generation of finite element models of dental structures and restorations...
  9. pmc Using occlusal wear information and finite element analysis to investigate stress distributions in human molars
    Stefano Benazzi
    Department of Anthropology, University of Vienna, Vienna, Austria
    J Anat 219:259-72. 2011
    Simulations based on finite element analysis (FEA) have attracted increasing interest in dentistry and dental anthropology for evaluating the stress and strain distribution in teeth under occlusal loading conditions...
  10. ncbi Creep behavior of the intact and meniscectomy knee joints
    M Kazemi
    Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, Canada T2N 1N4
    J Mech Behav Biomed Mater 4:1351-8. 2011
    ..For the femoral cartilage, the maximum principal stress was generally in agreement with the fiber direction, which indicated the essential role of fibers in load support of the tissue...
  11. pmc Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element models
    K Kupczik
    Hull York Medical School, The University of York, UK
    J Anat 210:41-53. 2007
    Crucial to the interpretation of the results of any finite element analysis of a skeletal system is a test of the validity of the results and an assessment of the sensitivity of the model parameters...
  12. ncbi Requirements for comparing the performance of finite element models of biological structures
    E R Dumont
    Department of Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA
    J Theor Biol 256:96-103. 2009
    ..imaging and computational power has fostered a rapid increase in the number of biologists using finite element analysis (FEA) to investigate the mechanical function of living and extinct organisms...
  13. ncbi Masticatory loading and bone adaptation in the supraorbital torus of developing macaques
    K Kupczik
    Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Am J Phys Anthropol 139:193-203. 2009
    ..By using finite element analysis (FEA), we are able to evaluate the hypothesis that strain energy density (SED) magnitudes are high in ..
  14. ncbi Nonlinear analysis of cartilage in unconfined ramp compression using a fibril reinforced poroelastic model
    L P Li
    Departments of Chemical Engineering, Institute of Biomedical Engineering, Ecole Polytechnique of Montreal, P O Box 6079, Station Centre Ville, Montreal, Quebec, Canada
    Clin Biomech (Bristol, Avon) 14:673-82. 1999
    ..To develop a biomechanical model for cartilage which is capable of capturing experimentally observed nonlinear behaviours of cartilage and to investigate effects of collagen fibril reinforcement in cartilage...
  15. ncbi Three-dimensional finite element modeling of human ear for sound transmission
    Rong Z Gan
    School of Aerospace and Mechanical Engineering, University of Oklahoma, Norman, OK 73019, USA
    Ann Biomed Eng 32:847-59. 2004
    ....
  16. ncbi Effect of adhesive layer properties on stress distribution in composite restorations--a 3D finite element analysis
    Pietro Ausiello
    Department of Cariology, School of Dentistry, University of Naples Federico II, Italy
    Dent Mater 18:295-303. 2002
    ..Teeth, adhesively restored with resin-based materials, were modeled by 3D-finite elements analysis that showed a premature failure during polymerization shrinkage and occlusal loading...
  17. ncbi A three-dimensional finite element analysis of the combined behavior of ligaments and menisci in the healthy human knee joint
    E Pena
    Group of Structural Mechanics and Material Modelling, Aragon Institute of Engineering Research I3A, University of Zaragoza, Maria de Luna, 3, E 50018 Zaragoza, Spain
    J Biomech 39:1686-701. 2006
    ..The results obtained reproduce the complex, nonuniform stress and strain fields that occur in the biological soft tissues involved and the kinematics of the human knee joint under a physiological external load...
  18. ncbi Depth-wise progression of osteoarthritis in human articular cartilage: investigation of composition, structure and biomechanics
    S Saarakkala
    Department of Physics, University of Kuopio, Kuopio, Finland
    Osteoarthritis Cartilage 18:73-81. 2010
    ..e., collagen and proteoglycans (PGs), during OA progression. Further, it is unknown how the depth-wise changes affect local tissue strains during compression. Our aim was to address these issues...
  19. pmc Can high-field MREIT be used to directly detect neural activity? Theoretical considerations
    R J Sadleir
    J Crayton Pruitt Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611 6131, USA
    Neuroimage 52:205-16. 2010
    ..We also propose the idea of using MREIT as an alternative means of studying neuromodulation...
  20. ncbi Study of reproducibility of human arterial plaque reconstruction and its effects on stress analysis based on multispectral in vivo magnetic resonance imaging
    Hao Gao
    Brunel Institute for Bioengineering, Brunel University, Uxbridge, Middlesex, UK
    J Magn Reson Imaging 30:85-93. 2009
    ..To quantify the uncertainties of carotid plaque morphology reconstruction based on patient-specific multispectral in vivo magnetic resonance imaging (MRI) and their impacts on the plaque stress analysis...
  21. ncbi Mechanics of chondrocyte hypertrophy
    C C van Donkelaar
    Department of Biomedical Engineering, Eindhoven University of Technology, 5600 MB, Eindhoven, The Netherlands
    Biomech Model Mechanobiol 11:655-64. 2012
    ..It provides a mechanistic explanation for the observation that collagen degradation results in chondrocyte hypertrophy, both under physiological and pathological conditions...
  22. ncbi Assessment of function-graded materials as fracture fixation bone-plates under combined loading conditions using finite element modelling
    H Fouad
    Department of Applied Medical Science, RCC, King Saud University, PO Box 28095, 11437 Riyadh, Saudi Arabia
    Med Eng Phys 33:456-63. 2011
    ..Therefore, the significant effects of using an FG bone-plate with a gap and the presence of torsional load on the resultant stress on the fracture fixation bone-plate system should be taken into consideration...
  23. pmc Calculation of shear stiffness in noise dominated magnetic resonance elastography data based on principal frequency estimation
    K P McGee
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Phys Med Biol 56:4291-309. 2011
    ....
  24. ncbi Effects of the bone-plate material and the presence of a gap between the fractured bone and plate on the predicted stresses at the fractured bone
    H Fouad
    Department of Applied Medical Science, RCC, King Saud University, P O Box 28095, 11437 Riyadh, Saudi Arabia
    Med Eng Phys 32:783-9. 2010
    ..The significant effects of using an FG bone-plate with a gap on the resultant Von Mises stresses on the bone underneath the plate and on the bone stress shielding should be taken into consideration during fractured bone fixation...
  25. pmc Male-female differences in the association between incident hip fracture and proximal femoral strength: a finite element analysis study
    J H Keyak
    Department of Radiological Sciences, University of California, Irvine, CA, USA
    Bone 48:1239-45. 2011
    ..013). These findings support further exploration of possible sex differences in the predictors of hip fracture and of sex-specific strategies for using FE analysis to manage osteoporosis...
  26. ncbi Analysis of biomechanical changes after removal of instrumentation in lumbar arthrodesis by finite element analysis
    Ho Joong Kim
    Yonsei Sarang Hospital, Seoul, Korea
    Med Biol Eng Comput 48:703-9. 2010
    ..This study demonstrated that removal of pedicle screws could decrease stiffness of fusion segments, which would reduce the disk stress of adjacent segments...
  27. ncbi Finite element simulations of a focal knee resurfacing implant applied to localized cartilage defects in a sheep model
    Krishnagoud Manda
    KTH Mechanics, Royal Institute of Technology, Osquars backe 18, SE 100 44 Stockholm, Sweden
    J Biomech 44:794-801. 2011
    ..Too deep positions, however, lead to high shear stresses in the cartilage edges around the implant. Mechanical sealing was achieved with a wedge shape of the implant, also useful for biochemical sealing of cartilage edges at the defect...
  28. ncbi Comparative evaluation of implant designs: influence of diameter, length, and taper on strains in the alveolar crest. A three-dimensional finite-element analysis
    Cynthia S Petrie
    Department of Restorative Dentistry, School of Dentistry, University of Missouri Kansas City, Kansas City, MO 64108, USA
    Clin Oral Implants Res 16:486-94. 2005
    ..Our aim was to analyze and compare systematically the relative and interactive effects of implant diameter, length, and taper on calculated crestal bone strains...
  29. pmc Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function
    Martin J Bishop
    University of Oxford Computing Laboratory, Parks Road, Oxford OX1 3QD, UK
    Am J Physiol Heart Circ Physiol 298:H699-718. 2010
    ..This highlights the utility of histoanatomically detailed models for investigations of cardiac function, in particular for future patient-specific modeling...
  30. pmc Association of hip strength estimates by finite-element analysis with fractures in women and men
    Shreyasee Amin
    Division of Rheumatology, Department of Internal Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Bone Miner Res 26:1593-600. 2011
    ..Furthermore, an estimated hip strength below 3000 N may represent a critical level of systemic skeletal fragility in both sexes that warrants further investigation...
  31. ncbi Local axial compressive mechanical properties of human carotid atherosclerotic plaques-characterisation by indentation test and inverse finite element analysis
    Chen Ket Chai
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    J Biomech 46:1759-66. 2013
    ....
  32. pmc Why do woodpeckers resist head impact injury: a biomechanical investigation
    Lizhen Wang
    Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, People s Republic of China
    PLoS ONE 6:e26490. 2011
    ..This biomechanical analysis makes it possible to visualize events during woodpecker pecking and may inspire new approaches to prevention and treatment of human head injury...
  33. ncbi Assessment of factors influencing finite element vertebral model predictions
    Alison C Jones
    Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, LS2 9JT, UK
    J Biomech Eng 129:898-903. 2007
    This study aimed to establish model construction and configuration procedures for future vertebral finite element analysis by studying convergence, sensitivity, and accuracy behaviors of semiautomatically generated models and comparing ..
  34. pmc Analyzing taphonomic deformation of ankylosaur skulls using retrodeformation and finite element analysis
    Victoria M Arbour
    Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada
    PLoS ONE 7:e39323. 2012
    ..The effects of sediment compaction are modeled using finite element analysis, and the resulting strain distributions are compared with the retrodeformed models as a test of the ..
  35. ncbi Development of specimen-specific finite element models of human vertebrae for the analysis of vertebroplasty
    V N Wijayathunga
    School of Mechanical Engineering, University of Leeds, Leeds, UK
    Proc Inst Mech Eng H 222:221-8. 2008
    ....
  36. ncbi Why do humans have chins? Testing the mechanical significance of modern human symphyseal morphology with finite element analysis
    Flora Gröning
    Department of Archaeology and Hull York Medical School, University of York, York, UK
    Am J Phys Anthropol 144:593-606. 2011
    ..This study uses finite element analysis to examine these symphyseal loads in a model of a modern human mandible...
  37. ncbi Effect of proximal wall height on all-ceramic crown core stress distribution: a finite element analysis study
    Paulo G Coelho
    Department of Biomaterials and Biomimetics, New York University College of Dentistry, 345 24th Street, Room 804s, New York, NY 10010, USA
    Int J Prosthodont 22:78-86. 2009
    Mechanical analyses of idealized crown-cement-tooth systems through finite element analysis (FEA) has provided valuable insight concerning design parameters and materials that favor lower stress patterns...
  38. pmc Biomechanical comparison of two different concepts for stand alone anterior lumbar interbody fusion
    Philipp Schleicher
    Center for Spinal Surgery and Neurotraumatology, BG Unfallklinik Frankfurt, Friedberger Landstrasse 430, 60389, Frankfurt, Germany
    Eur Spine J 17:1757-65. 2008
    ..b>Finite element analysis (FE) was also performed to investigate load and stress distribution within the implant in several loading ..
  39. pmc Biomechanical comparison of unilateral and bilateral pedicle screws fixation for transforaminal lumbar interbody fusion after decompressive surgery--a finite element analysis
    Shih Hao Chen
    Department of Orthopaedics, Tzu Chi General Hospital at Taichung and Tzu Chi University, Hualien, Taiwan
    BMC Musculoskelet Disord 13:72. 2012
    ..This study used finite element (FE) models to investigate biomechanical differences in ROM and stress on the neighboring structures after TLIF cages insertion in conjunction with posterior fixation...
  40. pmc A finite element analysis of the effect of electrode area and inter-electrode distance on the spatial distribution of the current density in tDCS
    Paula Faria
    Institute of Biophysics and Biomedical Engineering, University of Lisbon, Lisbon, Portugal
    J Neural Eng 8:066017. 2011
    ..Finally, the use of multiple small return electrodes may be more efficient than the use of a single large return electrode...
  41. pmc Model sensitivity and use of the comparative finite element method in mammalian jaw mechanics: mandible performance in the gray wolf
    Zhijie Jack Tseng
    Integrative and Evolutionary Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 6:e19171. 2011
    b>Finite Element Analysis (FEA) is a powerful tool gaining use in studies of biological form and function...
  42. ncbi The mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interactions in articular cartilage
    F Guilak
    Orthopaedic Research Laboratories, Departments of Surgery, Biomedical Engineering, and Mechanical Engineering and Materials Science, Duke University Medical Center, P O Box 3093, 375 MSRB, 27710, Durham, NC, USA
    J Biomech 33:1663-73. 2000
    ..Knowledge of the local stress and strain fields in the extracellular matrix is an important step in the interpretation of studies of mechanical signal transduction in cartilage explant culture models...
  43. ncbi Biomechanical study of mandible bone supporting a four-implant retained bridge: finite element analysis of the influence of bone anisotropy and foodstuff position
    A S Bonnet
    Laboratory of Mechanics, Biomechanics, Polymers and Structures LaBPS, ENIM, Ile du Saulcy 57045 Metz, France
    Med Eng Phys 31:806-15. 2009
    ..work was to study the biomechanical behavior of a "All-on-four" implant-supported prosthesis through a finite element analysis using either isotropic or anisotropic properties of bone...
  44. ncbi Valve-based microfluidic compression platform: single axon injury and regrowth
    Suneil Hosmane
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Lab Chip 11:3888-95. 2011
    ..At severe levels of injury (> 95 kPa), virtually all axons were instantaneously transected and nearly half (~46%) of these axons were able to regrow within the imaging period in the absence of exogenous stimulating factors...
  45. ncbi Spectrally resolved bioluminescence tomography with adaptive finite element analysis: methodology and simulation
    Yujie Lv
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, PO Box 2728, Beijing 100080, People s Republic of China
    Phys Med Biol 52:4497-512. 2007
    ..In terms of optical property errors and two sources of discernment in deeper positions, this BLT algorithm represents the unique predominance for BLT reconstruction...
  46. ncbi Numerical modeling of bone tissue adaptation--a hierarchical approach for bone apparent density and trabecular structure
    P G Coelho
    Mechanical and Industrial Engineering Department, FCT UNL, Portugal
    J Biomech 42:830-7. 2009
    ..Since, some computed microstructures have no permeability one concludes that bone tissue arrangement is not a simple stiffness maximization issue but biological factors also play an important role...
  47. ncbi Influence of implant length and diameter on stress distribution: a finite element analysis
    Lucie Himmlova
    Institute of Dental Research and Czech Technical University, Prague, Czech Republic
    J Prosthet Dent 91:20-5. 2004
    ..Masticatory forces acting on dental implants can result in undesirable stress in adjacent bone, which in turn can cause bone defects and the eventual failure of implants...
  48. ncbi Functional significance of strain distribution in the human mandible under masticatory load: numerical predictions
    I Ichim
    Department of Oral Sciences, Otago University, Walsh Building, 310 Great King Street, Dunedin 9001, New Zealand
    Arch Oral Biol 52:465-73. 2007
    ..We then relate the magnitude of these strains to Frost's mechanostat. Our results suggest that the cortical asymmetry of the human mandible is in fact not related to strain patterns generated during mastication...
  49. ncbi In vivo MRI-based 3D mechanical stress-strain profiles of carotid plaques with juxtaluminal plaque haemorrhage: an exploratory study for the mechanism of subsequent cerebrovascular events
    Z Teng
    University Department of Radiology, University of Cambridge, Level 5, Box 218, Addenbrooke s Hospital, Hills Rd, Cambridge CB2 0QQ, UK
    Eur J Vasc Endovasc Surg 42:427-33. 2011
    ..Three-dimensional mechanical analysis was employed to represent the critical mechanical stress (P-CStress) and stretch (P-CStretch) within the plaque...
  50. pmc Composition of the pericellular matrix modulates the deformation behaviour of chondrocytes in articular cartilage under static loading
    Petro Julkunen
    Department of Clinical Neurophysiology, Kuopio University Hospital, Kuopio, Finland
    Med Biol Eng Comput 47:1281-90. 2009
    ..The development of cartilage repair materials could benefit from this information...
  51. pmc Vascular smooth muscle cells ablation with endovascular nonthermal irreversible electroporation
    Elad Maor
    Biophysics Graduate Group, Department of Mechanical Engineering, 6124 Etcheverry Hall, University of California, Berkeley, CA 94720, USA
    J Vasc Interv Radiol 21:1708-15. 2010
    ..To evaluate the effect of endovascular nonthermal irreversible electroporation (NTIRE) on blood vessels...
  52. ncbi Region-specific tolerance criteria for the living brain
    Benjamin S Elkin
    Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, 1210 Amsterdam Ave, New York, NY, USA
    Stapp Car Crash J 51:127-38. 2007
    ....
  53. ncbi Finite element analysis performed on radius and tibia HR-pQCT images and fragility fractures at all sites in men
    Nicolas Vilayphiou
    INSERM Research Unit 831 and Université de Lyon, Lyon, France
    J Bone Miner Res 26:965-73. 2011
    ....
  54. pmc Finite element analysis of performance in the skulls of marmosets and tamarins
    Elizabeth R Dumont
    Department of Biology, University of Massachusetts Amherst, Amherst, MA, USA
    J Anat 218:151-62. 2011
    ..This analysis illustrates that differences in the shapes of the skulls of Callithrix and Saguinus confer differences in performance. Whether these aspects of performance are targets of selection awaits broader comparative analyses...
  55. ncbi Free body analysis, beam mechanics, and finite element modeling of the mandible of Alligator mississippiensis
    Laura B Porro
    Department of Organismal Biology and Anatomy, University of Chicago, Illinois 60637, USA
    J Morphol 272:910-37. 2011
    ..J.Morphol. 2011. © 2011 Wiley-Liss, Inc...
  56. ncbi Finite element analysis performed on radius and tibia HR-pQCT images and fragility fractures at all sites in postmenopausal women
    Nicolas Vilayphiou
    INSERM Research Unit 831 and Université de Lyon, Lyon, France
    Bone 46:1030-7. 2010
    Assessment of bone strength at the radius by micro-finite element analysis (muFEA) has already been associated with wrist fractures...
  57. pmc Finite element modelling of squirrel, guinea pig and rat skulls: using geometric morphometrics to assess sensitivity
    P G Cox
    Department of Musculoskeletal Biology, University of Liverpool, Liverpool, UK
    J Anat 219:696-709. 2011
    ..b>Finite element analysis (FEA) is an ideal technique to investigate the biomechanical implications of these specializations, but ..
  58. ncbi Transcranial direct current stimulation (tDCS) in a realistic head model
    ROSALIND J SADLEIR
    J Crayton Pruitt Department of Biomedical Engineering, University of Florida, Box 116131, Gainesville, FL 32611 6131, USA
    Neuroimage 51:1310-8. 2010
    ..The modeling also suggests that more targeted stimulations might be achieved by different electrode topologies...
  59. ncbi Nanoscale heterogeneity promotes energy dissipation in bone
    Kuangshin Tai
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Nat Mater 6:454-62. 2007
    ..The fundamental concepts discovered here are applicable to a broad class of biological materials and may serve as a design consideration for biologically inspired materials technologies...
  60. pmc Comparison of the effects of bilateral posterior dynamic and rigid fixation devices on the loads in the lumbar spine: a finite element analysis
    Antonius Rohlmann
    Biomechanics Laboratory, Orthopaedic Hospital, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany
    Eur Spine J 16:1223-31. 2007
    ..Thus, the results of this study demonstrate that a dynamic implant does not necessarily reduce axial spinal loads compared to an un-instrumented spine...
  61. ncbi Characterization of articular cartilage by combining microscopic analysis with a fibril-reinforced finite-element model
    Petro Julkunen
    Department of Physics, University of Kuopio, Kuopio, Finland
    J Biomech 40:1862-70. 2007
    ..The present study demonstrates that modern quantitative microscopic methods in combination with the FRPVE model are feasible methods to characterize the structure-function relationships of articular cartilage...
  62. ncbi Stochastic finite element framework for simultaneous estimation of cardiac kinematic functions and material parameters
    Pengcheng Shi
    Biomedical Research Laboratory, Department of Electrical and Electronic Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, Hong Kong
    Med Image Anal 7:445-64. 2003
    ....
  63. ncbi A finite element model of the human knee joint for the study of tibio-femoral contact
    Tammy L Haut Donahue
    Department of Mechanical Engineering, Michigan Technological University, Houghton 49931, USA
    J Biomech Eng 124:273-80. 2002
    ..However, unrealistic constraints on rotations other than flexion/extension can result in relatively large errors in contact variables...
  64. ncbi A constrained modulus reconstruction technique for breast cancer assessment
    A Samani
    Department of Medical Biophysics, University of Toronto, ON, Canada
    IEEE Trans Med Imaging 20:877-85. 2001
    ..Breast tissue modulus reconstruction using simulated data and phantom modulus reconstruction using experimental data indicate that the technique is robust...
  65. ncbi Three-dimensional finite element analysis of the foot during standing--a material sensitivity study
    Jason Tak Man Cheung
    Jockey Club Rehabilitation Engineering Centre, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China
    J Biomech 38:1045-54. 2005
    ..Peak bone stress was found at the third metatarsal in all calculated cases with a minimal increase of about 7% with soft tissue stiffening...
  66. pmc Patient-specific analysis of the volume of tissue activated during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH 44195, USA
    Neuroimage 34:661-70. 2007
    ....
  67. ncbi Improvements in vertebral body strength under teriparatide treatment assessed in vivo by finite element analysis: results from the EUROFORS study
    Christian Graeff
    Medical Physics, Department of Diagnostic Radiology, Michaelisstrasse 9, D 24105 Kiel, Germany
    J Bone Miner Res 24:1672-80. 2009
    ..FE variables showed a higher standardized response to changes than BMD measurements, but further studies are needed to show that the higher response represents a more accurate estimate of treatment-induced fracture risk reduction...
  68. ncbi Can the growth factors PTHrP, Ihh and VEGF, together regulate the development of a long bone?
    J E M Brouwers
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    J Biomech 39:2774-82. 2006
    ..The three growth factors, PTHrP, Ihh and VEGF, could potentially together regulate tissue differentiation...
  69. ncbi Modeling passive mechanical interaction between aqueous humor and iris
    J J Heys
    Department of Chemical Engineering, University of Colorado, Boulder 80309-0424, USA
    J Biomech Eng 123:540-7. 2001
    ..The results compare favorably with clinical observations, supporting the hypothesis that passive iris deformation can produce the iris contours observed using ultrasound biomicroscopy...
  70. ncbi The role of computational models in the search for the mechanical behavior and damage mechanisms of articular cartilage
    W Wilson
    Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, Eindhoven 5600 MB, The Netherlands
    Med Eng Phys 27:810-26. 2005
    ..So far the most common method to accomplish that is finite element analysis. This paper provides an overview of computational descriptions developed for this purpose, and what they ..
  71. ncbi The effect of anterior cruciate ligament injury on knee joint function under a simulated muscle load: a three-dimensional computational simulation
    Guoan Li
    Orthopaedic Biomechanics Laboratory, Harvard Medical School, Massachusetts General Hospital Beth Israel Deaconess Medical Center, Boston 02215, USA
    Ann Biomed Eng 30:713-20. 2002
    ....
  72. ncbi Nonlinear finite element analyses: advances and challenges in dental applications
    N Wakabayashi
    Department of Removable Prosthodontics, School of Dentistry, Iwate Medical University, 1 3 27 Chuodori, Morioka, Iwate 020 8580, Japan
    J Dent 36:463-71. 2008
    ..To discuss the development and current status of application of nonlinear finite element method (FEM) in dentistry...
  73. ncbi A dynamic study of thoracolumbar burst fractures
    Ruth K Wilcox
    School of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Bone Joint Surg Am 85:2184-9. 2003
    ....
  74. ncbi Biomechanical rupture risk assessment of abdominal aortic aneurysms: model complexity versus predictability of finite element simulations
    T C Gasser
    Department of Solid Mechanics, The Royal Institute of Technology KTH, School of Engineering Sciences, Osquars Backe 1, SE 100 44 Stockholm, Sweden
    Eur J Vasc Endovasc Surg 40:176-85. 2010
    ..Investigation of the predictability of finite element (FE) models regarding rupture risk assessment of abdominal aortic aneurysms (AAAs)...
  75. ncbi Sensitivities of medial meniscal motion and deformation to material properties of articular cartilage, meniscus and meniscal attachments using design of experiments methods
    Jiang Yao
    Department of Mechanical Engineering, University of Rochester, Rochester, NY 14627, USA
    J Biomech Eng 128:399-408. 2006
    ....
  76. ncbi Load-sharing between anterior and posterior elements in a lumbar motion segment implanted with an artificial disc
    A P Dooris
    Iowa Spine Research Center, Departments of Biomedical Engineering andOrthopaedics, University of Iowa, Iowa City, Iowa, USA
    Spine (Phila Pa 1976) 26:E122-9. 2001
    ....
  77. pmc The feeding biomechanics and dietary ecology of Australopithecus africanus
    David S Strait
    Department of Anthropology, University at Albany, 1400 Washington Avenue, Albany, NY 12222, USA
    Proc Natl Acad Sci U S A 106:2124-9. 2009
    ..Here, we test this hypothesis using finite element analysis in conjunction with comparative, imaging, and experimental methods...
  78. ncbi Finite-element analysis of biting behavior and bone stress in the facial skeletons of bats
    Elizabeth R Dumont
    Department of Biology, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Anat Rec A Discov Mol Cell Evol Biol 283:319-30. 2005
    ..The same was not true of Cynopterus, where factors other than feeding appear to have had a more significant impact on craniofacial morphology...
  79. ncbi Blood flow and vessel mechanics in a physiologically realistic model of a human carotid arterial bifurcation
    S Z Zhao
    Department of Chemical Engineering and Chemical Technology, Imperial College, London, UK
    J Biomech 33:975-84. 2000
    ..Stress concentration occurs at both the anterior and posterior aspects of the proximal internal bulb. These are also regions of low wall shear stress. The comparison of computed and measured wall movement generally shows good agreement...
  80. ncbi Convergence in a mechanically complex phenotype: detecting structural adaptations for crushing in cichlid fish
    C Darrin Hulsey
    Department of Ecology and Evolutionary Biology, University of Tennessee, Knoxville, Tennessee 37996, USA
    Evolution 62:1587-99. 2008
    ..The structural and mechanical analyses also suggest divergence found in polymorphic species could provide the substrate for trophic differences found in reproductively isolated cichlids...
  81. ncbi Finite element analysis of stresses in endodontically treated, dowel-restored teeth
    Erik Asmussen
    Department of Dental Materials, Faculty of Health Sciences, School of Dentistry, University of Copenhagen, 20 Nørre Allé, DK 2200 Copenhagen N, Denmark
    J Prosthet Dent 94:321-9. 2005
    ..Endodontically-treated, dowel-restored teeth may experience fracture, but investigations of variables related to fracture are often inconclusive and occasionally contradictory...
  82. pmc Effects of gape and tooth position on bite force and skull stress in the dingo (Canis lupus dingo) using a 3-dimensional finite element approach
    Jason Bourke
    School of Biological Earth and Environmental Sciences, University of New South Wales, Sydney, New South Wales, Australia
    PLoS ONE 3:e2200. 2008
    ..Stress data, combined with bite force information, suggested that there is an optimal bite angle of between 25 degrees and 35 degrees in C. l. dingo. The function of these rather small bite angles remains unclear...
  83. ncbi Role of cartilage collagen fibrils networks in knee joint biomechanics under compression
    R Shirazi
    Division of Applied Mechanics, Department of Mechanical Engineering, Ecole Polytechnique, P O Box 6079, Station Centre Ville, Montreal, Quebec, Canada H3C 3A7
    J Biomech 41:3340-8. 2008
    ....
  84. ncbi Statistical methods in finite element analysis
    Fazilat H Dar
    Department of Bio Medical Physics and Bio Engineering, University of Aberdeen, Scotland, UK
    J Biomech 35:1155-61. 2002
    b>Finite element analysis (FEA) is a commonly used tool within many areas of engineering and can provide useful information in structural analysis of mechanical systems...
  85. ncbi Open access high-resolution 3D morphology models of cat, gerbil, rabbit, rat and human ossicular chains
    Wasil H M Salih
    Laboratory of Biomedical Physics, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Hear Res 284:1-5. 2012
    ..The resolution of the CT images, from which the models are segmented, varies from 5.6 to 33.5 μm. Models are freely available in different formats at our website (http://www.ua.ac.be/bimef/models) for research and educational purposes...
  86. ncbi Computational neurotrauma--design, simulation, and analysis of controlled cortical impact model
    Haojie Mao
    Bioengineering Center, Wayne State University, Detroit, MI 48201, USA
    Biomech Model Mechanobiol 9:763-72. 2010
    ..The interaction effects of any two external parameters were not significant. This study demonstrates the potential of using numerical FE modeling to engineer better experimental TBI models in the future...
  87. ncbi In vitro evaluation of stiffness graded artificial hip joint femur head in terms of joint stresses distributions and dimensions: finite element study
    H Fouad
    Orthopedic Surgery Research Chair, King Saud University, Riyadh, Saudi Arabia
    J Mater Sci Mater Med 22:1589-98. 2011
    ....
  88. ncbi Finite element analysis of weakened roots restored with composite resin and posts
    Carla Santina de Miranda Coelho
    Department of Endodontics, School of Dentistry, Catholic University of Brasilia, Distrito Federal, Brazil
    Dent Mater J 28:671-8. 2009
    b>Finite element analysis (FEA) was used to investigate the influence of different post systems on the stress distribution of weakened teeth under oblique-load application...
  89. ncbi Finite element analysis of vulnerable atherosclerotic plaques: a comparison of mechanical stresses within carotid plaques of acute and recently symptomatic patients with carotid artery disease
    Umar Sadat
    University Department of Radiology, Addenbrooke s Hospital, University of Cambridge, Cambridge CB2 0QQ, UK
    J Neurol Neurosurg Psychiatry 81:286-9. 2010
    ..Biomechanical assessment of carotid plaques using high-resolution MRI can help examine the relationship between the timing of carotid plaque symptomology and maximum simulated plaque stress concentration...
  90. ncbi Mechanical response of nickel-titanium instruments with different cross-sectional designs during shaping of simulated curved canals
    H C Kim
    Department of Conservative Dentistry, School of Dentistry, Pusan National University, Busan, Korea
    Int Endod J 42:593-602. 2009
    ..To evaluate how different cross-sectional designs affect stress distribution in nickel-titanium (NiTi) instruments during bending, torsion and simulated shaping of a curved canal...
  91. ncbi Probabilistic finite element analysis of the uncemented hip replacement--effect of femur characteristics and implant design geometry
    Carolina Dopico-González
    Bioengineering Research Group, School of Engineering Sciences, University of Southampton, United Kingdom
    J Biomech 43:512-20. 2010
    ..It was demonstrated that results from a single model study should not be generalised to the entire population of femurs and that bone variability is an important factor that should be investigated in such analyses...
  92. pmc Finite element method (FEM), mechanobiology and biomimetic scaffolds in bone tissue engineering
    A Boccaccio
    Dipartimento di Ingegneria Meccanica e Gestionale, Politecnico di Bari, 70126 Bari, Italy
    Int J Biol Sci 7:112-32. 2011
    ....
  93. ncbi High resolution quantitative computed tomography-based assessment of trabecular microstructure and strength estimates by finite-element analysis of the spine, but not DXA, reflects vertebral fracture status in men with glucocorticoid-induced osteoporosis
    Christian Graeff
    Sektion Biomedizinische Bildgebung, Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Kiel, Germany
    Bone 52:568-77. 2013
    ..quantitative computed tomography (HRQCT)-based analysis of spinal bone density and microstructure, finite element analysis (FEA), and DXA were used to investigate the vertebral bone status of men with glucocorticoid-induced ..
  94. pmc Transcranial direct current stimulation in patients with skull defects and skull plates: high-resolution computational FEM study of factors altering cortical current flow
    Abhishek Datta
    Department of Biomedical Engineering, The City College of New York of CUNY, New York, NY 10031, USA
    Neuroimage 52:1268-78. 2010
    ..The predictions of this study are the first step to assess safety of transcranial electrical therapy in subjects with skull injuries and skull plates...
  95. pmc Considerations for reporting finite element analysis studies in biomechanics
    Ahmet Erdemir
    Computational Biomodeling Core, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    J Biomech 45:625-33. 2012
    ..b>Finite element analysis (FEA) has been widely used in the last few decades to understand and predict biomechanical phenomena...
  96. ncbi Three-dimensional finite element analysis of strength, stability, and stress distribution in orthodontic anchorage: a conical, self-drilling miniscrew implant system
    Shivani Singh
    Department of Orthodontics and Dentofacial Orthopedics, Manipal College of Dental Sciences, Mangalore, India
    Am J Orthod Dentofacial Orthop 141:327-36. 2012
    ....
  97. ncbi Experimentally validated three-dimensional finite element model of the rat for mild traumatic brain injury
    Michael Lamy
    Department of Fluid and Solid Mechanics, University of Strasbourg, IMFS, 2 rue Boussingault, 67000 Strasbourg, France
    Med Biol Eng Comput 51:353-65. 2013
    ..Results of our analysis tend to show that time-related metrics may be more suited for the explanation of mild TBI than commonly used peak metrics in the three anatomical regions of the brain...
  98. ncbi Patient-specific knee joint finite element model validation with high-accuracy kinematics from biplane dynamic Roentgen stereogrammetric analysis
    G Papaioannou
    Human Movement Sciences, MOVE Center, College of Health Sciences, University of Wisconsin Milwaukee, Room 364 Pavilion, P O Box 413, Milwaukee, WI 53201 0413, USA
    J Biomech 41:2633-8. 2008
    ..This local validation using accurate localized patient-specific geometry and meniscal kinematics was needed to enhance model fidelity at the level of contact between menisci and cartilage...
  99. ncbi The effect of the frontal plane tibiofemoral angle and varus knee moment on the contact stress and strain at the knee cartilage
    Nicholas H Yang
    Mechanical and Industrial Engineering Dept, Northeastern University, Boston, MA, USA
    J Appl Biomech 26:432-43. 2010
    Subject-specific models were developed and finite element analysis was performed to observe the effect of the frontal plane tibiofemoral angle on the normal stress, Tresca shear stress and normal strain at the surface of the knee ..
  100. ncbi Two dental implants designed for immediate loading: a finite element analysis
    Laurent Pierrisnard
    Faculty of Dental Surgery, Montrouge, University of Paris V, France
    Int J Oral Maxillofac Implants 17:353-62. 2002
    The aim of this study was to evaluate by finite element analysis the influence of the design of 3 different dental implants on micromovements, cervical shearing stress intensity, and stress distribution after occlusal loading.
  101. ncbi Mechanical stimulation to stimulate formation of a physiological collagen architecture in tissue-engineered cartilage: a numerical study
    Mehdi Khoshgoftar
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Comput Methods Biomech Biomed Engin 14:135-44. 2011
    ..Adding lateral compression may stimulate the formation of a deep zone with perpendicularly aligned fibres. These insights may be used to improve loading conditions for cartilage tissue engineering...

Research Grants63

  1. High Resolution Peripheral Quantitative CT
    MARY BETH LEONARD; Fiscal Year: 2013
    ..Importantly, HR-pQCT images can be used as input for [unreadable]-Finite Element Analysis (FEA) for estimation of whole bone strength or elastic moduli of trabecular bone...
  2. Early effects of PTH on the proximal femur
    Felicia Cosman; Fiscal Year: 2013
    ..Apart from the beneficial effect of TPTD on bone density and bone strength by finite element analysis at the hip, nothing is known about the mechanism of the effect of TPTD on the proximal femur...
  3. Bone Microarchitecture: The Framingham Osteoporosis Study
    Douglas P Kiel; Fiscal Year: 2013
    ..we will also determine the contribution of bone microarchitecture, and bone strength measured by micro-finite element analysis, to incidence of non-vertebral fragility fracture in women and men, and determine if the association ..
  4. Clinical Validation of BCT - Phase II
    DAVID KOPPERDAHL; Fiscal Year: 2010
    ..we term Biomechanical Computed Tomography (BCT), addresses this need through a combination of engineering finite element analysis, 3D quantitative computed tomography (QCT), and bone fracture biomechanics...
  5. The interaction of anabolic and antiresorptive agents in osteoporosis therapy
    Joy Tsai; Fiscal Year: 2013
    ..cortical thickness and porosity, trabecular microarchitecture, and estimated bone strength (via micro finite element analysis)...
  6. Development of Headwear To Prevent Fall-Related Injuries in Elderly Persons
    JAMES RIDDELL FERGUSON; Fiscal Year: 2011
    ..material characteristics using data from Phase I impact testing and conduct numerical modeling using finite element analysis, 2) conduct biochemical evaluation of these advanced materials on designer-enhanced prototypes, 3) ..
  7. Surgery to Prevent Postinfarction Ventricular Remodeling
    Robert C Gorman; Fiscal Year: 2013
    ..Myocardial stress distribution will be calculated using state-of-the-art finite element analysis based on the MRI strain data...
  8. Computational Biomechanics for Prediction of Osteoporotic Vertebral Fracture Risk
    Chamith Sudesh Rajapakse; Fiscal Year: 2013
    ..The proposed research holds the potential to provide an improved technique for early prediction of vertebral fractures and will serve well as a launching pad for the applicant to become an independent researcher. ..
  9. Ultra-high Resolution pQCT as a Biomarker of Bone Strength in Osteoporosis Trials
    ELIZABETH J SHANE; Fiscal Year: 2010
    ..ultra-structural details of trabecular microarchitecture, and yields datasets that can be subjected to finite element analysis (FEA) modeling to assess bone strength...
  10. MicroCT 100
    David H Kohn; Fiscal Year: 2010
    ..Software will also be included to calculate detailed bone histomorphometric parameters and to conduct finite element analysis. Increased throughput of the instrument will reduce turnover times for sample analysis while increased ..
  11. Bone Quality and Mechanical Competence In Chronic Kidney Disease
    Thomas L Nickolas; Fiscal Year: 2012
    ..b>Finite element analysis (FEA), a measure of bone strength, can be applied to HRpQCT data sets...
  12. Apical Access System with Universal Connector for Beating Heart LVAD Implantation
    Jorge Hernan Jimenez; Fiscal Year: 2013
    ..Testing to include: 600 Millio cycle fatigue, leakage/burst testing in pressurized hearts, Finite element analysis of anchoring components, sterilization validation and biocompatibility, anatomical fit and surgical ..
  13. Cortical Bone Porosity Identifies Diabetes Subjects With Fragility Fractures
    Thomas M Link; Fiscal Year: 2010
    ..concerning image post-processing to extract structural parameters including cortical porosity and finite element analysis derived surrogate markers of bone strength...
  14. BONE PROPERTIES IN HYPOPARATHYROIDISM: EFFECTS OF PTH
    John P Bilezikian; Fiscal Year: 2013
    ..absorptiometry, quantitative peripheral and central computed tomography (including high resolution pQCT, finite element analysis, Individual Trabecular Segmentation analysis, voxel- based QCT) and measurement of skeletal indices from ..
  15. Bone Metabolism and Body Composition in Young Athletes
    Madhusmita Misra; Fiscal Year: 2013
    ..are proposed in the current application, and it is hypothesized (1) that bone strength [assessed using finite element analysis (FEA)] is lower in AA compared with EA and non-athletes 14-21 y at baseline and decreases prospectively ..
  16. The Bone Trial of the Testosterone Trial
    Peter J Snyder; Fiscal Year: 2013
    ..end points are vBMD of the hip;bone strength and strength-to-density ratio in the spine and hip by finite element analysis determined from the QCT data;areal BMD of the lumbar spine, proximal hip and distal radius by DXA;serum ..
  17. Chronic Kidney Disease and PTH: Effects on the Postmenopausal Skeleton
    EMILY MARGARET STEIN; Fiscal Year: 2013
    ..State of the art non-invasive techniques, high-resolution peripheral computed tomography (HRpQCT) and finite element analysis (FEA), will allow us to distinguish trabecular and cortical compartments, discern trabecular ..
  18. BIOMECHANICAL ANALYSIS IN STRABISMUS SURGERY
    JOSEPH LOUIS DEMER; Fiscal Year: 2013
    ..and model behavior of orbital fibromuscular tissues, using the modern mechanical engineering technique of finite element analysis (FEA) to integrate data on EOM and connective tissue properties obtained using novel techniques of ..
  19. A New Hip Fracture Risk Prediction Tool Based on Common Predictors and Hip Geomer
    Samy Missoum; Fiscal Year: 2012
    ..The third aim is to validate and compare the SVM-based risk with and without the use of finite element analysis and develop a hip fracture risk calculator for the web...
  20. Micro-Mechanical Role of Hypertension in Intimal Hyperplasia
    Ghassan S Kassab; Fiscal Year: 2013
    ..To elucidate the mechanical role of hypertension on IH using the validated models of Aim 2 combined with finite element analysis and experimental validation...
  21. 3-D Visualization and Prediction of Spine Fractures
    Elise F Morgan; Fiscal Year: 2012
    ..Aim #2 will use micro-finite element analysis to quantify the anisotropic elastic properties throughout the centrum...
  22. Growth and Remodeling Model of Abdominal Aortic Aneurysm: Toward Clinical Applica
    Seungik Baek; Fiscal Year: 2013
    ..Conventional finite element analysis, however, uses advances in medical imaging only to define patient-specific lesion geometry, but do not ..
  23. Vertical and shear forces and distributions in the diabetic foot
    Scott Barnes; Fiscal Year: 2012
    ..quantities can be accurately mapped to the physical location on the foot;Aim 3, Phase II) Utilizing the finite element analysis model, as independently established by Innovative Science Solutions Inc...
  24. Skeletal Regulation of Cortical and Trabecular Bone by Parathyroid Hormone
    Natalie Cusano; Fiscal Year: 2013
    ..bone turnover;bone mineral density by dual-energy x-ray absorptiometry (DXA) and high resolution peripheral quantitative computed tomography (HRpQCT);Finite Element Analysis (FEA);and Individual Trabeculae Segmentation (ITS) analysis.
  25. Real-time Ultrasonic Monitoring of Tumor Ablation
    Tomy Varghese; Fiscal Year: 2013
    ..b>Finite element analysis (FEA) to model deformations induced by RF/microwave displacements will be performed to better understand ..
  26. Hign Performance MEMS Deformable Mirror for Adaptive Optics Retinal Imaging
    MICHAEL HELMBRECHT; Fiscal Year: 2009
    ..This research will develop the DM over two iterations, refining the manufacturing each step of the way. Finite element analysis, performance testing, and failure studies will feed into the design to create robust mirrors...
  27. Simple &Safe Implantable Device for Treatment of Gastroesophageal Reflux Disease
    CLAUDE NMN TIHON; Fiscal Year: 2013
    ..Preliminary work has been completed on the anatomy and pathophysiology of the LES including a finite element analysis on an analogous model of urethral incontinence...
  28. Cooling Suit for First Responders
    GIRISH SRINIVAS; Fiscal Year: 2011
    ..In addition, we will perform a system analysis using a 2D software and a finite element analysis. The design analysis will form the basis of the prototype fabrication in the Phase II project...
  29. Implant/Construct Interactions in the Biomechanics of Total Hip Dislocation
    Thomas Brown; Fiscal Year: 2009
    ..Realistic finite element analysis is an ideal vehicle for systematically assessing the complex interactions of the many factors influencing ..
  30. Clinical Validation of BCT
    DAVID KOPPERDAHL; Fiscal Year: 2007
    ..we term Biomechanical Computed Tomography (BCT), addresses this need through a combination of engineering finite element analysis, 3D quantitative computed tomography (QCT), and bone biomechanics...
  31. SURGERY FOR ACUTE MYOCARDIAL INFARCTION
    L Edmunds; Fiscal Year: 2000
    ..He has refined techniques of biaxial stress-extension testing of tissue samples, finite element analysis of left ventricular infarction, sonomicrometry array localization of left ventricular and mitral annular ..
  32. BIOMIMETICS OF BONE REGENERATION
    Jill Helms; Fiscal Year: 2002
    ..In specific aim 4 we propose to use finite element analysis to define the mechanical environment of the distraction site...
  33. PHYSIOLOGY AND MEASUREMENT OF VOCAL FOLD VIBRATION
    Jack Jiang; Fiscal Year: 2000
    ..As a supplement to the excised larynx model, a finite element analysis (FEA) computer model and a mucosal wave model will be studied...
  34. EMG propagation in planar muscles for prosthesis control
    Todd Kuiken; Fiscal Year: 2007
    ..This will be accomplished with a series of generalized planar FE models. Next, finite element analysis will be used to determine the effect of anatomical manipulations for improving surface EMG signal ..
  35. Computational and Experimental Analysis of Tibial Tuberosity Transfers
    John J Elias; Fiscal Year: 2011
    ..The second aim is to utilize both discrete element analysis and finite element analysis, with multiple representations for cartilage, to replicate the experimental studies...
  36. SEGMENTAL BONE & JOINT REPLACEMENT AFTER TUMOR RESECTION
    Edmund Chao; Fiscal Year: 2000
    ..Implant and fixation strength will be tested in vitro under bending and torsional loading conditions. Finite element analysis will be adopted to study the stress transfer phenomenon with and without extracortical bone bridging...
  37. Chaos in Human Phonation and Its Measurement
    Jack Jiang; Fiscal Year: 2007
    ..In part I, research will focus on the chaotic dynamics of the lumped-parameter model of vocal folds and finite element analysis (FEA)...
  38. OPTIMIZED STRESS STATES IN CERAMIC-BASED RESTORATIONS
    Kenneth Anusavice; Fiscal Year: 2003
    ..developments will be employed for the analyses proposed: 1) a three-dimensional visco-elastic element for finite element analysis of incompatibility stresses, 2) thermal tempering in liquid media to alter residual stress profiles and ..
  39. Energy Absorbing Transit Safe Wheelchair Caster
    LINDA VANROOSMALEN; Fiscal Year: 2004
    ..3. Get evidence through dynamic impact testing and finite element analysis on loading patterns and failure modes of the prototype caster-fork assemblies. 4...
  40. ADVANCED BIOFIDOLIC LOWER EXTREMITY PROSTHESIS RESEARCH
    MORENO WHITE; Fiscal Year: 2003
    ..Assures satisfactory performance by analyzing the design using state of the art finite element analysis prior to fabrication and 4...
  41. A minimally invasive cardiac assist device
    Walid Aboulhosn; Fiscal Year: 2004
    ..e., the Hemopump). Phase I goals: 1) design and analyze prototype using finite element analysis of hydraulics and electomechanical coupling, 2) build working models and test fixtures, 3) conduct bench ..
  42. A MULTIFUNCTIONAL SURGICAL SUPPORT SURFACE
    James Price; Fiscal Year: 2001
    ..project will focus on the optimization of the air cell grid design by means of a large displacement finite element analysis. Prototypes of the support surface constructs will be fabricated and tested to establish the performance ..
  43. Human Lumbar Facet Capsule Biomechanics
    Partap Khalsa; Fiscal Year: 2004
    ..Determine material properties of the facet joint capsule; and 3) Develop a mathematical model of the capsule using finite element analysis to enable estimating stress at any location within the capsule during loading.
  44. Image Guided Constitutive Modeling of the Brain Tissue
    Oskar Skrinjar; Fiscal Year: 2004
    ..AIM 3: Inverse finite element analysis of the strain fields and derivation of constitutive models within the novel thermodynamically consistent ..
  45. DEVELOPMENT OF AN IMPLANT FOR FINGER JOINT ARTHROPLASTY
    WILFRED LYNCH; Fiscal Year: 1993
    ..Proposed research is to demonstrate feasibility of the Arthroflex concept. Kinematic and finite element analysis (FEA) will be used to analyze forces on joints during normal hand usage...
  46. MECHANICS OF SPINE SURGERY - A FINITE ELEMENT ANALYSIS
    Vijay Goel; Fiscal Year: 1993
    ..Such analyses may afford us an opportunity to identify parameters that will help design an optimal fixation device...
  47. Accessible Mounting and Positioning Technology
    DIANNE GOODWIN; Fiscal Year: 2006
    ..Loads calculated by MotionWorks are used in Finite Element analysis, to optimize the arm design...
  48. Rabbit Model for In Vivo Monitoring of Bone Structure
    Michael Voor; Fiscal Year: 2003
    ..When the volume of trabecular bone is sufficiently large, micromechanical finite element analysis (micro-FEA) can also be done to nondestructively test the mechanical behavior and predict the strength of ..
  49. A Repositionable Tissue Anchor for Osteoporortic Bone
    DANIEL KELSCH; Fiscal Year: 2004
    ..The development of this anchor and associated insertion tooling will utilize a finite element analysis design tool...
  50. Bone Fluid Flow and its Regulatory Role in Adaptation
    Yi Xian Qin; Fiscal Year: 2006
    ..A poroelastic finite element analysis will be developed, which will evaluate the correlation between fluid flow and resultant adaptation...
  51. IDIOPATHIC OSTEOPOROSIS IN PREMENOPAUSAL WOMEN
    Elizabeth Shane; Fiscal Year: 2009
    ..Quantitative bone histomorphometry, microcomputed tomography (micro-CT), finite element analysis (micro-FE) will be applied to assess bone structure, remodeling, connectivity and strength...
  52. Finite element analysis of middle ear acoustics
    JAMES TUCK LEE; Fiscal Year: 2005
    ..This can then be used with ossicle and cochlea models for a complete middle ear model, which can be compared with existing measurements, and used to simulate damage or surgical reconstruction to the middle ear. ..
  53. Microcomputed tomography device (Scanco microCT35)
    Karl Insogna; Fiscal Year: 2007
    ..5 micron) imaging capacity, as well as the ability to undertake finite element analysis. These capabilities are absolutely required to sustain the current pace of discovery in musculoskeletal ..
  54. A HUMAN ACCOMMODATION MODEL
    JANE KORETZ; Fiscal Year: 1991
    ..A second type of modelling approach - finite element analysis - will also be employed to expand the scope of the study without the necessity of developing an even more ..
  55. DENTAL IMPLANT BIOMECHANICS--ROBOTIC SIMULATOR
    LARRY BREEDING; Fiscal Year: 1993
    ..Investigators, through finite element analysis and biomechanical models, have attempted to predict these force levels; however, these techniques are ..
  56. ECAD:Enhanced Coronary Artery Disease Phantom for MRA
    Thomas Burke; Fiscal Year: 2006
    ..technologies are significantly improved through the introduction of powerful computer based, finite element analysis and CAD/CAM integration with in house CNC prototype hardware...
  57. Knee Implant Wear Evaluation-An Integrated Approach
    Timothy Wright; Fiscal Year: 2005
    ..Computational simulations using finite element analysis (FEA) have limitations as well - wear performance has been assessed only from singular stress or strain ..
  58. EXPIRATORY MUSCLE ACTIVATION TO PRODUCE COUGH
    Anthony DiMarco; Fiscal Year: 2003
    ..around and within the spinal cord during SCS and MS will be measured and used in conjunction with finite element analysis modeling techniques to determine optimum electrode and coil design...
  59. BIOMECHANICAL FACTORS IN OA OF THE GLENOHUMERAL JOINT
    VAN MOW; Fiscal Year: 1999
    ..tensile, compressive, shear and permeability properties of cartilage at the joint; and three-dimensional finite element analysis of contact stresses correlated with experimental data...
  60. Cooling Suit for First Responders
    GIRISH SRINIVAS; Fiscal Year: 2007
    ..In addition, we will perform a system analysis using a 2D software and a finite element analysis. The design analysis will form the basis of the prototype fabrication in the Phase II project...
  61. Subdiffraction Fluorescence imaging of Bone Biomechanics
    Michael Morris; Fiscal Year: 2006
    ..The results will be coupled with finite element analysis models to estimate strain distributions...
  62. Validation of Injury Reduction by Bumper Airbags for Heavy Truck Collisions
    PETER DREHER; Fiscal Year: 2007
    ..Phase I of this project used non-linear, dynamic, finite element analysis and computational fluid mechanics to model the airbags in collisions and cross winds...
  63. MECHANISMS OF ACOUSTIC PERCEPTION AND ORIENTATION
    O DELL HENSON; Fiscal Year: 2000
    ..5. Complete the collection of MRM images of the cochleae of bats and other mammals and explore the modeling (finite element analysis - FEA) of vibrational patterns, given the dimensions of the cochleae reconstructed from MRM.