gestational age

Summary

Summary: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.

Top Publications

  1. ncbi The research implications of the selection of a gestational age estimation method
    Courtney D Lynch
    Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Paediatr Perinat Epidemiol 21:86-96. 2007
  2. ncbi Birth weight in relation to morbidity and mortality among newborn infants
    D D McIntire
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235 9032, USA
    N Engl J Med 340:1234-8. 1999
  3. ncbi An overview of mortality and sequelae of preterm birth from infancy to adulthood
    Saroj Saigal
    Department of Paediatrics, McMaster University, Hamilton, ON, Canada
    Lancet 371:261-9. 2008
  4. pmc Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, 2015 Uppergate Dr, Atlanta, GA 30322, USA
    Pediatrics 126:443-56. 2010
  5. ncbi Circulating angiogenic factors and the risk of preeclampsia
    Richard J Levine
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Department of Health and Human Services, Bethesda, MD 20892, USA
    N Engl J Med 350:672-83. 2004
  6. ncbi British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood
    T J Cole
    MRC Dunn Nutrition Centre, Cambridge, UK
    Stat Med 17:407-29. 1998
  7. ncbi Soluble endoglin and other circulating antiangiogenic factors in preeclampsia
    Richard J Levine
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Department of Health and Human Services, Bethesda, MD 20892, USA
    N Engl J Med 355:992-1005. 2006
  8. ncbi Meta-analysis of neurobehavioral outcomes in very preterm and/or very low birth weight children
    Cornelieke Sandrine Hanan Aarnoudse-Moens
    Division of Neonatology, Department of Pediatrics, Erasmus University Medical Centre Sophia Children s Hospital, Rotterdam, Netherlands
    Pediatrics 124:717-28. 2009
  9. pmc Gestational weight gain and child adiposity at age 3 years
    Emily Oken
    Obesity Prevention Program, Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Am J Obstet Gynecol 196:322.e1-8. 2007
  10. ncbi Soluble endoglin contributes to the pathogenesis of preeclampsia
    Shivalingappa Venkatesha
    Center for Vascular Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Nat Med 12:642-9. 2006

Detail Information

Publications346 found, 100 shown here

  1. ncbi The research implications of the selection of a gestational age estimation method
    Courtney D Lynch
    Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Paediatr Perinat Epidemiol 21:86-96. 2007
    There are three primary methods of gestational age estimation: dating based on last menstrual period (LMP), ultrasound-based dating and neonatal estimates...
  2. ncbi Birth weight in relation to morbidity and mortality among newborn infants
    D D McIntire
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235 9032, USA
    N Engl J Med 340:1234-8. 1999
    At any given gestational age, infants with low birth weight have relatively high morbidity and mortality...
  3. ncbi An overview of mortality and sequelae of preterm birth from infancy to adulthood
    Saroj Saigal
    Department of Paediatrics, McMaster University, Hamilton, ON, Canada
    Lancet 371:261-9. 2008
    ..Morbidity is inversely related to gestational age; however, there is no gestational age, including term, that is wholly exempt...
  4. pmc Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, 2015 Uppergate Dr, Atlanta, GA 30322, USA
    Pediatrics 126:443-56. 2010
    ..data from the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network on care of and morbidity and mortality rates for very low birth weight infants, according to gestational age (GA).
  5. ncbi Circulating angiogenic factors and the risk of preeclampsia
    Richard J Levine
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Department of Health and Human Services, Bethesda, MD 20892, USA
    N Engl J Med 350:672-83. 2004
    ..Limited data suggest that excess circulating soluble fms-like tyrosine kinase 1 (sFlt-1), which binds placental growth factor (PlGF) and vascular endothelial growth factor (VEGF), may have a pathogenic role...
  6. ncbi British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood
    T J Cole
    MRC Dunn Nutrition Centre, Cambridge, UK
    Stat Med 17:407-29. 1998
    ..The ability to express anthropometry as SDS greatly simplifies growth assessment...
  7. ncbi Soluble endoglin and other circulating antiangiogenic factors in preeclampsia
    Richard J Levine
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Department of Health and Human Services, Bethesda, MD 20892, USA
    N Engl J Med 355:992-1005. 2006
    ..Since soluble endoglin, another antiangiogenic protein, acts together with sFlt1 to induce a severe preeclampsia-like syndrome in pregnant rats, we examined whether it is associated with preeclampsia in women...
  8. ncbi Meta-analysis of neurobehavioral outcomes in very preterm and/or very low birth weight children
    Cornelieke Sandrine Hanan Aarnoudse-Moens
    Division of Neonatology, Department of Pediatrics, Erasmus University Medical Centre Sophia Children s Hospital, Rotterdam, Netherlands
    Pediatrics 124:717-28. 2009
    ..We conducted a quantitative meta-analysis of studies published between 1998 and 2008 on academic achievement, behavioral functioning, and EF with the aim of providing aggregated measures of effect size for these outcome domains...
  9. pmc Gestational weight gain and child adiposity at age 3 years
    Emily Oken
    Obesity Prevention Program, Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Am J Obstet Gynecol 196:322.e1-8. 2007
    ..The purpose of this study was to examine the associations of gestational weight gain with child adiposity...
  10. ncbi Soluble endoglin contributes to the pathogenesis of preeclampsia
    Shivalingappa Venkatesha
    Center for Vascular Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Nat Med 12:642-9. 2006
    ..Our results suggest that sEng may act in concert with sFlt1 to induce severe preeclampsia...
  11. ncbi On the importance--and the unimportance--of birthweight
    A J Wilcox
    Epidemiology Branch, National Institute of Environmental Health Sciences, Durham NC 27709, USA
    Int J Epidemiol 30:1233-41. 2001
    ..While the ordinary approaches to birthweight are not well grounded, the links between birthweight and a range of health outcomes may nonetheless reflect the workings of biological mechanisms with implications for human health...
  12. ncbi Neonatal MRI to predict neurodevelopmental outcomes in preterm infants
    Lianne J Woodward
    Canterbury Child Development Research Group, Department of Psychology, University of Canterbury and the Van der Veer Institute for Parkinson s and Brain Research, Christchurch, New Zealand
    N Engl J Med 355:685-94. 2006
    ..Very preterm infants are at high risk for adverse neurodevelopmental outcomes. Magnetic resonance imaging (MRI) has been proposed as a means of predicting neurodevelopmental outcomes in this population...
  13. ncbi Long-term medical and social consequences of preterm birth
    Dag Moster
    Department of Public Health and Primary Health Care, University of Bergen, Norway
    N Engl J Med 359:262-73. 2008
    ..Advances in perinatal care have increased the number of premature babies who survive. There are concerns, however, about the ability of these children to cope with the demands of adulthood...
  14. pmc Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors
    Boris Novakovic
    Cancer, Disease and Developmental Epigenetics, Murdoch Childrens Research Institute, Royal Children s Hospital and Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia
    BMC Genomics 12:529. 2011
    ..However, the factors contributing to this variation in gene expression remain poorly understood...
  15. pmc A nearly continuous measure of birth weight for gestational age using a United States national reference
    Emily Oken
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, USA
    BMC Pediatr 3:6. 2003
    ..the determinants and sequelae of fetal growth requires a continuous measure of birth weight adjusted for gestational age. Published United States reference data, however, provide estimates only of the median and lowest and highest ..
  16. ncbi Neurologic and developmental disability at six years of age after extremely preterm birth
    Neil Marlow
    School of Human Development, University of Nottingham, Nottingham, United Kingdom
    N Engl J Med 352:9-19. 2005
    ..Birth before 26 weeks of gestation is associated with a high prevalence of neurologic and developmental disabilities in the infant during the first two years of life...
  17. ncbi Weights of placentae from small-for-gestational age infants revisited
    S Heinonen
    Department of Obstetrics and Gynecology, University Hospital of Kuopio, Finland
    Placenta 22:399-404. 2001
    ..to investigate the association between placental weight and birthweight in appropriate (AGA) and small for gestational age (SGA) infants...
  18. ncbi Natural history of brain lesions in extremely preterm infants studied with serial magnetic resonance imaging from birth and neurodevelopmental assessment
    Leigh E Dyet
    Department of Paediatrics, Medical Research Council Clinical Sciences Centre, Imperial College, Hammersmith Campus, London, United Kingdom
    Pediatrics 118:536-48. 2006
    ....
  19. ncbi Effects of Plasmodium vivax malaria in pregnancy
    F Nosten
    Shokio Malaria Research Unit, Mae Sot, Thailand
    Lancet 354:546-9. 1999
    ..P. falciparum infection has harmful effects in pregnancy, but the effects of P. vivax have not been characterised. We investigated the effects of P. vivax infection during pregnancy...
  20. ncbi Diagnosis and management of gestational hypertension and preeclampsia
    Baha M Sibai
    Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0526, USA
    Obstet Gynecol 102:181-92. 2003
    ..The decision between delivery and expectant management depends on fetal gestational age, fetal status, and severity of maternal condition at time of evaluation...
  21. ncbi A new and improved population-based Canadian reference for birth weight for gestational age
    M S Kramer
    Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Canada
    Pediatrics 108:E35. 2001
    ..fetal growth references all suffer from 1 or more major methodologic problems, including errors in reported gestational age, biologically implausible birth weight for gestational age, insufficient sample sizes at low gestational age, ..
  22. ncbi Intrauterine transmission and clinical outcome of 248 pregnancies with primary cytomegalovirus infection in relation to gestational age
    Gisela Enders
    Institute of Virology, Infectiology und Epidemiology e V, Rosenbergstraße 85, 70193 Stuttgart, Germany
    J Clin Virol 52:244-6. 2011
    ..The risk of intrauterine cytomegalovirus (CMV) infection and disease in the fetus or newborn largely depends on time of primary maternal infection during pregnancy...
  23. pmc Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies)
    Kate L Costeloe
    Centre for Paediatrics, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    BMJ 345:e7976. 2012
    ..To determine survival and neonatal morbidity for babies born between 22 and 26 weeks' gestation in England during 2006, and to evaluate changes in outcome since 1995 for babies born between 22 and 25 weeks' gestation...
  24. pmc On the pitfalls of adjusting for gestational age at birth
    Allen J Wilcox
    Epidemiology Branch MD A3 05, National Institute of Environmental Health Sciences, P O Box 12233, Durham, NC 27709, USA
    Am J Epidemiol 174:1062-8. 2011
    ..When investigators analyze the association of risk factors with neonatal outcomes, adjustment for gestational age as a mediating variable will lead to bias...
  25. ncbi Nasal CPAP or intubation at birth for very preterm infants
    Colin J Morley
    Neonatal Services, Royal Women s Hospital, Melbourne, Australia
    N Engl J Med 358:700-8. 2008
    ....
  26. ncbi New intrauterine growth curves based on United States data
    Irene E Olsen
    Rd, LDN, c o Louise Lawson, PhD, Kennesaw State, Department of Math and Stats, Box 1204, Building 12, 1000 Chastain Rd, Kennesaw, GA 30144 5591, USA
    Pediatrics 125:e214-24. 2010
    ..The objective of this study was to create and validate new intrauterine weight, length, and head circumference growth curves using a contemporary, large, racially diverse US sample and compare with the Lubchenco curves...
  27. ncbi Grey and white matter distribution in very preterm adolescents mediates neurodevelopmental outcome
    Chiara Nosarti
    Department of Psychiatry, King s College London Institute of Psychiatry, Denmark Hill, London, UK
    Brain 131:205-17. 2008
    ..white (WM) and grey matter (GM) distribution in VPT adolescents and controls, and the association with gestational age and neonatal ultrasound findings in the VPT individuals...
  28. ncbi Genetic and environmental influences on birth weight, birth length, head circumference, and gestational age by use of population-based parent-offspring data
    Astrid Lunde
    Section for Epidemiology and Medical Statistics, Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Am J Epidemiol 165:734-41. 2007
    Familial correlations in birth weight and gestational age have been explained by fetal and maternal genetic factors, mainly in studies on offspring of twins...
  29. pmc Malaria in pregnancy: the difficulties in measuring birthweight
    M J Rijken
    Shoklo Malaria Research Unit, Mae Sot, Tak, Thailand
    BJOG 118:671-8. 2011
    ..Seventy seven per cent explained how gestational age was estimated...
  30. ncbi Gestational age at birth and mortality in young adulthood
    Casey Crump
    Department of Medicine, Stanford University, 900 Blake Wilbur Dr, Stanford, CA 94304 2205, USA
    JAMA 306:1233-40. 2011
    Preterm birth is the leading cause of infant mortality in developed countries, but the association between gestational age at birth and mortality in adulthood remains unknown.
  31. ncbi Changes in neurodevelopmental outcomes at 18 to 22 months' corrected age among infants of less than 25 weeks' gestational age born in 1993-1999
    Susan R Hintz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA
    Pediatrics 115:1645-51. 2005
    ..Increased survival rates for extremely preterm, extremely low birth weight infants during the postsurfactant era have been reported, but data on changes in neurosensory and developmental impairments are sparse...
  32. pmc Risk of respiratory morbidity in term infants delivered by elective caesarean section: cohort study
    Anne Kirkeby Hansen
    Perinatal Epidemiology Research Unit, Aarhus University Hospital, Brendstrupgaardsvej 100, Skejby, 8200 Aarhus N, Denmark
    BMJ 336:85-7. 2008
    ..To investigate the association between elective caesarean sections and neonatal respiratory morbidity and the importance of timing of elective caesarean sections...
  33. ncbi Impact of labor induction, gestational age, and maternal age on cesarean delivery rates
    Linda J Heffner
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Obstet Gynecol 102:287-93. 2003
    ..To quantify the impact of labor induction and maternal age on cesarean delivery rates in nulliparous and multiparous women between 36 and 42 weeks' gestation...
  34. ncbi The influence of obesity and diabetes on the prevalence of macrosomia
    Hugh M Ehrenberg
    Case Western Reserve University School of Medicine, Department of Reproductive Biology, MetroHealth Medical Center, Cleveland, Ohio, USA
    Am J Obstet Gynecol 191:964-8. 2004
    ..This study was undertaken to determine the relative contribution of abnormal pregravid maternal body habitus and diabetes on the prevalence of large-for-gestational-age infants...
  35. ncbi Fetal spine ossification: the gender and individual differences illustrated by ultrasonography
    M Vignolo
    Department of Pediatrics, First Pediatric Clinic, University of Genoa, G Gaslini Institute, Genoa, Italy
    Ultrasound Med Biol 31:733-8. 2005
    ..of detection of sacral vertebral structures increased progressively with a regular pattern in relation to gestational age. Spinal length at first ultrasound examination was slightly correlated with time of appearance of sacral ..
  36. pmc Obstetric ultrasound scanning by local health workers in a refugee camp on the Thai-Burmese border
    M J Rijken
    Shoklo Malaria Research Unit SMRU, Mae Sot, Thailand
    Ultrasound Obstet Gynecol 34:395-403. 2009
    Ultrasound examination of the fetus is a powerful tool for assessing gestational age and detecting obstetric problems but is rarely available in developing countries...
  37. ncbi The contribution of mild and moderate preterm birth to infant mortality. Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System
    M S Kramer
    1020 Pine Ave W, Montreal, Quebec, Canada H3A 1A2
    JAMA 284:843-9. 2000
    ..However, infants born at 32 through 36 weeks are more common and their public health impact has not been well studied...
  38. pmc Gestational age at delivery and special educational need: retrospective cohort study of 407,503 schoolchildren
    Daniel F Mackay
    Section of Public Health, University of Glasgow, Glasgow, United Kingdom
    PLoS Med 7:e1000289. 2010
    ..Previous studies have demonstrated an association between preterm delivery and increased risk of special educational need (SEN). The aim of our study was to examine the risk of SEN across the full range of gestation...
  39. pmc Effects of gestational age at birth on health outcomes at 3 and 5 years of age: population based cohort study
    Elaine M Boyle
    Department of Health Sciences, University of Leicester, Leicester LE1 6TP, UK
    BMJ 344:e896. 2012
    ..To investigate the burden of later disease associated with moderate/late preterm (32-36 weeks) and early term (37-38 weeks) birth...
  40. ncbi The frequency and severity of placental findings in women with preeclampsia are gestational age dependent
    Julie S Moldenhauer
    Department of Obstetrics and Gynecology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Am J Obstet Gynecol 189:1173-7. 2003
    The purpose of this study was to evaluate placental lesions found in women with preeclampsia compared with normotensive control subjects and to determine whether the presence of these lesions are related to gestational age at delivery.
  41. ncbi Chronic lung disease after premature birth
    Eugenio Baraldi
    Department of Pediatrics, Unit of Respiratory Medicine and Allergy, Unit of Neonatal Intensive Care, University of Padua, School of Medicine, Padua, Italy
    N Engl J Med 357:1946-55. 2007
  42. ncbi Ossification timing of sacral vertebrae by ultrasound in the mid-second trimester of pregnancy
    P De Biasio
    Department of Obstetrics and Gynaecology, University of Genoa, G Gaslini Institute, Genoa, Italy
    Prenat Diagn 23:1056-9. 2003
    ..The aim of the study was to establish the ossification timing of sacral vertebrae by ultrasonography in the second trimester of pregnancy, for the diagnosis of caudal regression syndrome with isolated sacral agenesis...
  43. ncbi The NICHD neonatal research network: changes in practice and outcomes during the first 15 years
    Avroy A Fanaroff
    Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Semin Perinatol 27:281-7. 2003
    ..Advances in perinatal care within NICHD Network centers have resulted in marked improvements in survival. Further advances are required to increase survival free of neonatal morbidity or neurodevelopmental impairment...
  44. pmc A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for
    Roberto Romero
    Perinatology Research Branch, National Institute of Child Health and Human Development, NIH DHHS, Bethesda, MD 20892, USA
    J Matern Fetal Neonatal Med 21:9-23. 2008
    ..of these angiogenic and anti-angiogenic factors differ prior to development of disease among patients with normal pregnancies and those destined to develop PE (preterm and term) or to deliver a small for gestational age (SGA) neonate.
  45. ncbi Early fetal development of the human cerebellum
    Kwang Ho Cho
    Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Medical Science, 344 2 Sinyong dong, Iksan, Jeonbuk, Korea
    Surg Radiol Anat 33:523-30. 2011
    ..Consequently, in the early stages, it appears that the cerebellar hemisphere and vermis develop independently of each other...
  46. pmc Maternal and fetal variation in genes of cholesterol metabolism is associated with preterm delivery
    K M Steffen
    University of Iowa College of Medicine, Iowa City, IA 52242, USA
    J Perinatol 27:672-80. 2007
    ..To examine the contribution of variants in fetal and maternal cholesterol metabolism genes in preterm delivery (PTD)...
  47. ncbi Amniotic fluid: not just fetal urine anymore
    Mark A Underwood
    Department of Pediatrics, University of California, Davis School of Medicine, Davis, CA 95616, USA
    J Perinatol 25:341-8. 2005
    ..This article reviews recent discoveries and the current understanding of the origin and circulation of AF and its nutritive, protective, and diagnostic functions. Future directions for AF research are also discussed...
  48. ncbi Neonatal anthropometric charts: the Italian neonatal study compared with other European studies
    Enrico Bertino
    Dipartimento di Scienze Pediatriche e dell Adolescenza, Universita degli Studi di Torino, Torino, Italy
    J Pediatr Gastroenterol Nutr 51:353-61. 2010
    ....
  49. ncbi Modifiable determinants of fetal macrosomia: role of lifestyle-related factors
    Nanna Voldner
    Department of Obstetrics and Gynecology, University of Oslo, Rikshospitalet Medical Centre, Oslo, Norway
    Acta Obstet Gynecol Scand 87:423-9. 2008
    ....
  50. pmc Timing of elective repeat cesarean delivery at term and neonatal outcomes
    Alan T N Tita
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Alabama at Birmingham, 619 19th St South, Birmingham, AL 35249, USA
    N Engl J Med 360:111-20. 2009
    ..We assessed associations between elective cesarean delivery at term (37 weeks of gestation or longer) but before 39 weeks of gestation and neonatal outcomes...
  51. ncbi Increased fetal adiposity: a very sensitive marker of abnormal in utero development
    Patrick M Catalano
    Department of Reproductive Biology, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH 44109, USA
    Am J Obstet Gynecol 189:1698-704. 2003
    ....
  52. ncbi Comparison of pregnancy dating by last menstrual period, ultrasound scanning, and their combination
    David A Savitz
    Carolina Population Center, The Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 27599, USA
    Am J Obstet Gynecol 187:1660-6. 2002
    The purpose of this study was to evaluate the accuracy of algorithms for the assignment of gestational age with the use of the last menstrual period and early ultrasound information.
  53. pmc Epidemiology of preterm birth
    Janet Tucker
    Dugald Baird Centre, Department of Obstetrics and Gynaecology, University of Aberdeen
    BMJ 329:675-8. 2004
  54. pmc Association between local traffic-generated air pollution and preeclampsia and preterm delivery in the south coast air basin of California
    Jun Wu
    Program in Public Health, College of Health Sciences, University of California, Irvine, California 92697 7555, USA
    Environ Health Perspect 117:1773-9. 2009
    ..Increasing evidence suggests that air pollution adversely affects pregnancy outcomes. Yet few studies have examined how local traffic-generated emissions affect preeclampsia in addition to preterm birth...
  55. ncbi Role of insulin-like growth factors in embryonic and postnatal growth
    J Baker
    Department of Genetics and Development, Columbia University, New York, New York 10032
    Cell 75:73-82. 1993
    ....
  56. ncbi Australian national birthweight percentiles by gestational age
    C L Roberts
    NSW Centre for Perinatal Health Services Research, Department of Obstetrics and Gynaecology, University of Sydney
    Med J Aust 170:114-8. 1999
    To develop national birthweight percentiles by gestational age for male and female singleton infants born in Australia, and to compare the birthweight percentiles of Indigenous and non-Indigenous infants.
  57. ncbi Preterm premature rupture of the membranes
    Brian M Mercer
    Department of Obstetrics and Gynecology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio 44109 1989, USA
    Obstet Gynecol 101:178-93. 2003
    ..An understanding of gestational age-dependent neonatal morbidity and mortality is important in determining the potential benefits of conservative ..
  58. ncbi The neural basis of response inhibition and attention allocation as mediated by gestational age
    Emma J Lawrence
    Department of Psychological Medicine, Institute of Psychiatry, King s College London, United Kingdom
    Hum Brain Mapp 30:1038-50. 2009
    ....
  59. ncbi One-year survival of extremely preterm infants after active perinatal care in Sweden
    Vineta Fellman
    Department of Obstetrics and Gynecology, Lund University Hospital, S 221 85 Lund, Sweden
    JAMA 301:2225-33. 2009
    ..Up-to-date information on infant survival after extremely preterm birth is needed for assessing perinatal care services, clinical guidelines, and parental counseling...
  60. ncbi Birth characteristics and subsequent risks of maternal cardiovascular disease: effects of gestational age and fetal growth
    Anna Karin Edstedt Bonamy
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    Circulation 124:2839-46. 2011
    Prior studies showing an inverse relationship between low birth weight in offspring and maternal risks of cardiovascular diseases (CVD) are limited by lack of information on gestational age and/or insufficient adjustment for confounders.
  61. pmc Quantitative anatomy of the growing abdominal aorta in human fetuses: an anatomical, digital and statistical study
    Michał Szpinda
    Department of Normal Anatomy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland
    Med Sci Monit 18:BR419-26. 2012
    ..Advances in perinatal medicine have required an extensive knowledge of fetal aorto-iliac measurements. The present study was performed to compile reference data for dimensions of the abdominal aorta at varying gestational ages...
  62. pmc Altered basal cortisol levels at 3, 6, 8 and 18 months in infants born at extremely low gestational age
    Ruth E Grunau
    Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada
    J Pediatr 150:151-6. 2007
    ..Little is known about the developmental trajectory of cortisol levels in preterm infants after hospital discharge...
  63. ncbi The impact of very premature birth on the psychological health of mothers
    Leigh Davis
    Centre for Nursing Research, School of Nursing, Queensland University of Technology, Kelvin Grove Campus, Locked Bag, No 2, Red Hill, QLD 4059, Australia
    Early Hum Dev 73:61-70. 2003
    ..The birth of a very premature infant is a critical event in the life of a family and studies have shown that mothers of these infants are at greater risk of psychological distress than mothers of full-term infants...
  64. pmc Classification of stillbirth by relevant condition at death (ReCoDe): population based cohort study
    Jason Gardosi
    Perinatal Institute, Birmingham B6 5RQ
    BMJ 331:1113-7. 2005
    ..To develop and test a new classification system for stillbirths to help improve understanding of the main causes and conditions associated with fetal death...
  65. ncbi Australian national birthweight percentiles by sex and gestational age, 1998-2007
    Timothy A Dobbins
    Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia
    Med J Aust 197:291-4. 2012
    To present updated national birthweight percentiles by gestational age for male and female singleton infants born in Australia.
  66. ncbi Risk of perinatal death in early-onset intrauterine growth restriction according to gestational age and cardiovascular Doppler indices: a multicenter study
    Monica Cruz-Lemini
    Department of Maternal Fetal Medicine Institut Clinic de Ginecologia, Obstetricia i Neonatologia, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, and Centro de Investigación Biomédica en Red de Enfermedades Raras, Barcelona, Spain
    Fetal Diagn Ther 32:116-22. 2012
    To assess the value of gestational age and cardiovascular Doppler indices in predicting perinatal mortality in a multicenter cohort of early-onset intrauterine growth-restricted (IUGR) fetuses.
  67. ncbi High and low hemoglobin levels during pregnancy: differential risks for preterm birth and small for gestational age
    K S Scanlon
    Division of Nutrition and Physical Activity and the Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Obstet Gynecol 96:741-8. 2000
    To examine the association of maternal hemoglobin during pregnancy with preterm birth and small for gestational age (SGA).
  68. ncbi Psychosocial stress and pregnancy outcome
    Calvin J Hobel
    Department of Obstetrics, Gynecology and Pediatrics, Division of Maternal Fetal Medicine, Burns and Allen Research Institute, Cedars Sinai Medical Center, The David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Clin Obstet Gynecol 51:333-48. 2008
    ..Future directions for prevention of adverse pregnancy outcomes are discussed and suggest that an entirely new approach may be necessary...
  69. ncbi First- and second-trimester ultrasound assessment of gestational age
    Robin B Kalish
    Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Am J Obstet Gynecol 191:975-8. 2004
    ..The purpose of this study was to evaluate and compare the accuracy of first- and second-trimester ultrasound assessment of fetal age...
  70. ncbi Neurodevelopmental disabilities and special care of 5-year-old children born before 33 weeks of gestation (the EPIPAGE study): a longitudinal cohort study
    Beatrice Larroque
    INSERM, UMR S149, IFR69, Research Unit on Perinatal Health and Women s Health, Villejuif, France Université Pierre et Marie Curie Paris 6, Paris, France
    Lancet 371:813-20. 2008
    ..We aimed to investigate neurodevelopmental outcome and use of special health care at 5 years of age in a population-based cohort of very preterm children...
  71. ncbi Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms
    Barbara Schmidt
    Department of Pediatrics, McMaster University, HSC 3N11E, 1200 Main St W, Hamilton, Ontario, Canada L8N 3Z5
    JAMA 289:1124-9. 2003
    ..Despite more than 2 decades of outcomes research after very preterm birth, clinicians remain uncertain about the extent to which neonatal morbidities predict poor long-term outcomes of extremely low-birth-weight (ELBW) infants...
  72. ncbi Chronic lung disease of prematurity and intrauterine growth retardation: a population-based study
    Mithilesh K Lal
    Neonatal Unit, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester, United Kingdom
    Pediatrics 111:483-7. 2003
    To determine the risk of chronic lung disease (CLD) in small for gestational age (SGA) preterm infants in comparison to appropriately grown and large for gestational age (LGA) infants.
  73. ncbi Improved survival rates with increased neurodevelopmental disability for extremely low birth weight infants in the 1990s
    Deanne Wilson-Costello
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
    Pediatrics 115:997-1003. 2005
    ....
  74. ncbi A global reference for fetal-weight and birthweight percentiles
    Rafael T Mikolajczyk
    Department of Clinical Epidemiology, Bremen Institute for Prevention Research and Social Medicine, Bremen, Germany
    Lancet 377:1855-61. 2011
    Definition of small for gestational age in various populations worldwide remains a challenge...
  75. ncbi Reduction in postnatal cumulative nutritional deficit and improvement of growth in extremely preterm infants
    Thibault Senterre
    Department of Neonatology, University of Liege, CHU de Liege, CHR de la Citadelle, Belgium
    Acta Paediatr 101:e64-70. 2012
    To evaluate the influence of gestational age (GA) on cumulative nutritional deficit and postnatal growth in extremely preterm (EPT) infants after optimizing nutritional protocol as recently recommended.
  76. ncbi Induction of labour versus expectant monitoring for gestational hypertension or mild pre-eclampsia after 36 weeks' gestation (HYPITAT): a multicentre, open-label randomised controlled trial
    Corine M Koopmans
    Department of Obstetrics and Gynaecology, University Medical Centre, Groningen, Netherlands
    Lancet 374:979-88. 2009
    ..We investigated whether induction of labour in women with a singleton pregnancy complicated by gestational hypertension or mild pre-eclampsia reduces severe maternal morbidity...
  77. ncbi Changes in the gestational age distribution among U.S. singleton births: impact on rates of late preterm birth, 1992 to 2002
    Michael J Davidoff
    National Office, March of Dimes, White Plains, NY 10605, USA
    Semin Perinatol 30:8-15. 2006
    ..Analyzing gestational age by mode of delivery, the distribution of spontaneous births shifted to the left, with 39 weeks becoming the ..
  78. ncbi Decreasing incidence and severity of cerebral palsy in prematurely born children
    Ingrid C van Haastert
    Department of Neonatology, Wilhelmina Children s Hospital University Medical Center Utrecht, Utrecht, The Netherlands
    J Pediatr 159:86-91.e1. 2011
    To examine incidence and severity of cerebral palsy (CP), and associated factors among preterm survivors (gestational age <34 weeks), admitted to a neonatal intensive care unit from 1990-2005.
  79. ncbi IL-1beta and IL-8 in human fetal membranes: changes with gestational age, labor, and culture conditions
    C L Elliott
    Institute of Obstetrics and Gynaecology, Imperial College School of Medicine, London, UK
    Am J Reprod Immunol 46:260-7. 2001
    ..This study aimed to characterize their concentrations in fetal membranes and any changes in these with advancing gestation and to define as to whether there are interactions between the membranes in their expression...
  80. ncbi Neonatal mortality and morbidity rates in late preterm births compared with births at term
    Donald D McIntire
    Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center, Dallas, Texas 75235 9032, USA
    Obstet Gynecol 111:35-41. 2008
    ....
  81. ncbi New Dutch reference curves for birthweight by gestational age
    Gerard H A Visser
    Dept of Obstetrics, University Medical Center, Lundlaan 6, 3584 EA Utrecht, The Netherlands
    Early Hum Dev 85:737-44. 2009
    ..To construct new Dutch reference curves for birthweight by parity, sex and ethnic background...
  82. ncbi Decreased term and postterm birthweight in the United States: impact of labor induction
    Xun Zhang
    Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec, Canada
    Am J Obstet Gynecol 203:124.e1-7. 2010
    We sought to assess recent trends in falling mean birthweight (BW) and gestational age (GA) among US non-Hispanic white singleton live births >or=37 weeks of gestation and the contribution of increased rates of induction to these ..
  83. pmc Intensive care for extreme prematurity--moving beyond gestational age
    Jon E Tyson
    Center for Clinical Research and Evidence Based Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA
    N Engl J Med 358:1672-81. 2008
    Decisions regarding whether to administer intensive care to extremely premature infants are often based on gestational age alone. However, other factors also affect the prognosis for these patients.
  84. ncbi How does early ultrasound scan estimation of gestational age lead to higher rates of preterm birth?
    Hong Yang
    Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec, Canada
    Am J Obstet Gynecol 186:433-7. 2002
    Early ultrasound scanning estimation of gestational age is known to increase the reported preterm delivery rate (<37 completed weeks) compared with estimation by date of the last normal menstrual period, but it is unclear how this ..
  85. ncbi Comparison of gestational age at birth based on last menstrual period and ultrasound during the first trimester
    Caroline S Hoffman
    Department of Epidemiology, University of North Carolina at Chapel Hill, NC, USA
    Paediatr Perinat Epidemiol 22:587-96. 2008
    Reported last menstrual period (LMP) is commonly used to estimate gestational age (GA) but may be unreliable. Ultrasound in the first trimester is generally considered a highly accurate method of pregnancy dating...
  86. ncbi Socio-economic inequality in preterm birth: a comparative study of the Nordic countries from 1981 to 2000
    Christina B Petersen
    National Institute of Public Health, Copenhagen, Denmark
    Paediatr Perinat Epidemiol 23:66-75. 2009
    ..Information on gestational age and maternal socio-economic position was obtained from the NorCHASE database, which includes comparable ..
  87. pmc Survival of very preterm infants: Epipage, a population based cohort study
    B Larroque
    Epidemiological Research Unit on Perinatal and Women s Health, U149 INSERM Villejuif, France
    Arch Dis Child Fetal Neonatal Ed 89:F139-44. 2004
    ..To evaluate the outcome for all infants born before 33 weeks gestation until discharge from hospital...
  88. ncbi Evaluation of maternal thyroid function during pregnancy: the importance of using gestational age-specific reference intervals
    Rt Stricker
    DIANALAB SA, 6 rue de la Colline, Geneve, 1205 Switzerland
    Eur J Endocrinol 157:509-14. 2007
    ..However, occult thyroid disease and physiologic changes associated with pregnancy can complicate interpretation of maternal thyroid function tests (TFTs)...
  89. ncbi New charts for ultrasound dating of pregnancy and assessment of fetal growth: longitudinal data from a population-based cohort study
    B O Verburg
    The Generation R Study Group, Erasmus Medical Center, Sophia Children s Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Ultrasound Obstet Gynecol 31:388-96. 2008
    Correct assessment of gestational age and fetal growth is essential for optimal obstetric management...
  90. ncbi Menstrual versus clinical estimate of gestational age dating in the United States: temporal trends and variability in indices of perinatal outcomes
    Cande V Ananth
    Division of Epidemiology and Biostatistics, Department of Obstetrics, Gynecology, and Reproductive Sciences, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08901 1977, USA
    Paediatr Perinat Epidemiol 21:22-30. 2007
    Accurate estimation of gestational age early in pregnancy is paramount for obstetric care decisions and for determining fetal growth and other conditions that may necessitate timing the iatrogenic intervention or delivery...
  91. ncbi The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation
    Barbara J Law
    Department of Pediatrics and Child Health, University of Manitoba and the Winnipeg Health Sciences Center, Winnipeg, Canada
    Pediatr Infect Dis J 23:806-14. 2004
    ..This study sought to identify independent risk factors for hospitalization for RSV infection...
  92. ncbi Association of a woman's own birth weight with subsequent risk for gestational diabetes
    Kim E Innes
    Southeastern Rural Mental Health Center, McLeod Hall, University of Virginia, 202 15th St SW, Charlottesville, VA 22903 3306, USA
    JAMA 287:2534-41. 2002
    ....
  93. ncbi Educational outcomes in extremely preterm children: neuropsychological correlates and predictors of attainment
    Samantha Johnson
    Department of Health Sciences, University of Leicester, Leicester, UK
    Dev Neuropsychol 36:74-95. 2011
    ..Neonatal complications combined with assessments of early cognitive function provide moderate prediction for educational outcomes in children born extremely preterm...
  94. ncbi Final height in short children born small for gestational age treated with growth hormone
    Jovanna Dahlgren
    Goteborg Pediatric Growth Research Center, Institute for the Health of Women and Children, The Sahlgrenska Academy at Goteborg University, 416 85 Goteborg, Sweden
    Pediatr Res 57:216-22. 2005
    ..observational study was to assess the long-term growth responses to GH treatment of children born small for gestational age (SGA). GH treatment was begun before puberty and continued to final height (FH)...
  95. ncbi Quantification of deep gray matter in preterm infants at term-equivalent age using manual volumetry of 3-tesla magnetic resonance images
    Latha Srinivasan
    Department of Pediatrics, Hammersmith Hospital, Du Cane Road, London W12 0NS, United Kingdom
    Pediatrics 119:759-65. 2007
    ..The aim of our study was to test this hypothesis by direct measurement of thalamic and lentiform nuclei volumes in preterm infants at term-equivalent age and term-born controls using manual volumetry...
  96. pmc Climate extremes and the length of gestation
    Payam Dadvand
    Centre for Research in Environmental Epidemiology CREAL, Barcelona, Spain
    Environ Health Perspect 119:1449-53. 2011
    ..Although future climate is predicted to have more extreme heat conditions, the available evidence on the impact of these conditions on pregnancy length is very scarce and inconclusive...
  97. pmc The ELGAN study of the brain and related disorders in extremely low gestational age newborns
    T M O'Shea
    Department of Pediatrics Neonatology, Wake Forest University Health Sciences, Medical Center Blvd, Winston Salem, NC 27157, USA
    Early Hum Dev 85:719-25. 2009
    Extremely low gestational age newborns (ELGANs) are at increased risk for structural and functional brain abnormalities.
  98. ncbi Trends in preterm birth: singleton and multiple pregnancies in the Netherlands, 2000-2007
    J M Schaaf
    Department of Medical Informatics Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands
    BJOG 118:1196-204. 2011
    ..Our aim was to describe trends in preterm birth among singleton and multiple pregnancies in the Netherlands...
  99. pmc Estimation of gestational age from fundal height: a solution for resource-poor settings
    Lisa J White
    Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 7LJ, UK
    J R Soc Interface 9:503-10. 2012
    Many women in resource-poor settings lack access to reliable gestational age assessment because they do not know their last menstrual period; there is no ultrasound (US) and methods of newborn gestational age dating are not practised by ..
  100. pmc Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women
    Kim G Harley
    Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, California, United States of America
    PLoS ONE 6:e23923. 2011
    ..We explored whether paraoxonase (PON1), a key enzyme involved in detoxification of OPs, could be an effect modifier in this association...
  101. ncbi Early administration of low-dose aspirin for the prevention of preterm and term preeclampsia: a systematic review and meta-analysis
    Stéphanie Roberge
    Department of Social and Preventive Medicine, Universite Laval, Quebec City, Que, Canada
    Fetal Diagn Ther 31:141-6. 2012
    ..To compare the effect of early administration of aspirin on the risk of preterm and term preeclampsia...

Research Grants74

  1. Hybrid Optical/Doppler Imaging of Ischemia in NEC - a multicenter trial
    David A Benaron; Fiscal Year: 2010
    ..Ninety percent of NEC cases occur in infants born before 36 weeks'gestational age, occurring in up to 10% of all very-low-birth-weight (VLBW, <1500g) neonates [2]...
  2. Diagnosis of Subglottic Stenosis and Edema in Neonates Using OCT
    Brian Wong; Fiscal Year: 2013
    ..morphologic and structural features obtained with OCT with physiologic and functional variables such as gestational age, weight, and number of failed extubations in order to identify variables that can be used to better predict ..
  3. A Novel Thioredoxin Mimetic Prodrug for Prevention of Bronchopulmonary Dysplasia
    Prakash Jagtap; Fiscal Year: 2013
    ..proteins, such as superoxide dismutase and Trx, that are present in insufficient quantity at an early gestational age. Our innovation is based upon the administration of a novel agent, R-908, a prodrug of a Trx mimetic (R-901) ..
  4. Predicting Bilirubin-induced Auditory Toxicity in Infants with Severe Jaundice
    Sanjiv B Amin; Fiscal Year: 2010
    ..and the USA with common interests and complementary roles will collaborate to enroll 100 infants = 34 weeks gestational age with severe jaundice over two year period...
  5. The effect of trichloroethylene exposure on adverse pregnancy outcomes
    Iman Hassan; Fiscal Year: 2013
    ..provided by applicant): Adverse pregnancy outcomes, including preterm birth, low birth weight, small for gestational age, intrauterine growth restriction and stillbirth,are significant determinants of infant mortality and ..
  6. Antenatal Betamethasone in Late Preterm Gestation Lambs
    SATYANARAYANA LAKSHMINRUSIMHA; Fiscal Year: 2010
    ..surfactant production and release) affect late preterm infants at a higher rate than infants of more advanced gestational age. Practice guidelines of the American College of Obstetricians and Gynecologists (ACOG) recommend tocolysis ..
  7. Parental age at birth and risk of adult-onset cancer in female offspring
    Yani Lu; Fiscal Year: 2013
    ..Biological evidence of higher levels of circulating estrogens with advancing gestational age and higher chance of germ cell mutations and DNA damage from older fathers (but not older mothers) supports ..
  8. The Impact of Sleep-Disordered Breathing on Adverse Pregnancy Outcomes
    LOUISE M O apos BRIEN; Fiscal Year: 2010
    ..such symptoms and signs may predict two key adverse outcomes, pre-eclampsia in the mother and small size for gestational age in the infant...
  9. Mechanisms of Airway Smooth Muscle Hypertrophy
    Marc B Hershenson; Fiscal Year: 2013
    ..biomarkers for the development of BPD;accounting for the potential influences of gender, birth weight and gestational age, isolation of mesenchymal stromal cells increased the adjusted odds ratio of BPD over 31-fold...
  10. EEG Synchrony, perinatal risk and outcome: analysis of CHIME data
    PHILIP GEORGE GRIEVE; Fiscal Year: 2010
    ..for poor outcomes are not altered by neonatal care such as socioeconomic status, sex, birth weight and gestational age at birth...
  11. Human developmental toxicity of metal mixture exposure from e-waste recycling
    Aimin Chen; Fiscal Year: 2010
    ..Pregnancy outcomes (stillbirth, gestational length, preterm birth, birth weight, small for gestational age [SGA], birth length, head circumference, anogenital distance [AGD]), thyroid hormones (TSH, T4, T3), and ..
  12. Genome-wide DNA Methylation Profiles Associated with Abnormal Intrauterine Growth
    Cristina Montagna; Fiscal Year: 2013
    ..environment, marked by the extremes of fetal growth (intrauterine growth restriction (IUGR) and large for gestational age (LGA)), can have major effects in determining long-term disease susceptibility, particularly in regards to ..
  13. Climate Change and Adverse Birth Outcomes: Assessing the Vulnerability of Pregnan
    Shao Lin; Fiscal Year: 2013
    ..weeks) and moderately preterm (32-37 weeks), and small-for-gestational-age (below 10% of birth weight for gestational age)...
  14. Preconception Nutrition, Endocrine Disruptors, Reproductive Outcomes
    Xiaobin Wang; Fiscal Year: 2013
    ..dysfunction, time to conception, early pregnancy loss (EPL), spontaneous abortion (SAB), and birth outcomes (gestational age, birth weight, length, and head circumference);(3) Preconception BMI and Micronutrients: including serum ..
  15. Pluripotent Stem Cells: Modeling syncytiotrophoblast development and pathogenesis
    Danny J Schust; Fiscal Year: 2013
    ..We will test this hypothesis in vitro using iPSCs derived from the umbilical cords of babies born to mothers with severe preeclampsia and gestational age-matched control iPSCs.
  16. In utero programming of the dopamine system: behavior, neuroanatomy &epigenetics
    Teresa M Reyes; Fiscal Year: 2013
    ..These small-for- gestational age (SGA) babies face increased risk for immediate morbidity and mortality, as well as long-term neurobehavioral ..
  17. Biomarker Profiles for Early Diagnosis of Sepsis in Neonates
    JAMES PRESTON MAPES; Fiscal Year: 2011
    ..In addition, a proposed normal physiological range of MAP analytes for VLBW infants based on gestational age, birth weight and postnatal age will be developed...
  18. Prenatal stress biology, infant body composition and obesity risk
    Sonja Entringer; Fiscal Year: 2013
    ..programming of obesity have relied on measures of either size at birth (such as low birth weight or small-for-gestational age birth), or fetal and early postnatal growth velocity, as markers of adverse intrauterine exposures...
  19. Weight management for improved pregnancy outcomes
    Victor J Stevens; Fiscal Year: 2012
    ..gain during pregnancy, the amount of weight retained after delivery, and the proportion of large for gestational age infants. Secondary outcomes will include multiple safety measures of the mothers and their babies...
  20. Mother Sibling Interactions
    Julie A Thompson; Fiscal Year: 2010
    ..study will use a longitudinal, comparative, mixed method design to explore the impact of a VLBW (d33 weeks gestational age) infant on the mother-sibling interactions and sibling adjustment...
  21. GWA Mapping: Maternal Metabolism-Birth Weight Interactions
    WILLIAM LOWE; Fiscal Year: 2009
    ..birth weight, ponderal index, head circumference and adiposity) allowing for other known influences such as gestational age, parity, and maternal weight gain...
  22. Regulation of Maternal Fuel Supply and Neonatal Adiposity
    LINDA ANNE BARBOUR; Fiscal Year: 2013
    ..as a major fuel source affecting fetal fat accretion, the alarming increase in the number of large for gestational age (LGA) infants are being born primarily to obese women who do not fit diagnostic criteria for GDM...
  23. Randomized Trial of Antenatal Late Preterm Steroids (ALPS) - Clinical Coordinatin
    Ronald Wapner; Fiscal Year: 2012
    ..b>Gestational age is determined by a standardized algorithm prior to randomization...
  24. Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies
    RITA MARIE RYAN; Fiscal Year: 2013
    ..The lymphocytic phenotype will be analyzed particulariy in the context of gestational age and maternal-fetal stressors capable of modulating oxidative stress (oxygen exposure, infection and ..
  25. Maternal genitourinary infections and adverse perinatal outcomes
    Abdullah Hel Baqui; Fiscal Year: 2013
    ..CHWs will prospectively collect data on pregnancy outcomes and neonatal and maternal morbidity. Gestational age will be determined by maternal report of last menstrual period...
  26. Effects of prenatal stress exposure on childhood physical and metabolic outcomes
    Kelsey Needham Dancause; Fiscal Year: 2013
    ..the effects of prenatal stress exposure on birth outcomes (birth weight, stature, and head circumference for gestational age) in both cohorts using already available data...
  27. Metabolic Consequences of bariatric surgery on pregnant and lactating rats and th
    Bernadette E Grayson; Fiscal Year: 2013
    ..offspring due to gestational diabetes, hypertension and preeclampsia, difficulties in delivery of large-for-gestational age (LGA) infants and decreased capacity and quality of breast milk in the postpartum period3-5...
  28. Medications Development for the Pregnant Opiate Addict
    Mahmoud S Ahmed; Fiscal Year: 2010
    ..The hypothesis is: "The activity of placental metabolic enzymes and efflux transporters depends on gestational age and is under genetic and metabolic control"...
  29. Maternal-Fetal Conflict: The Effect of Imprinted Genes on Fetal Growth
    Ronald M Adkins; Fiscal Year: 2010
    Individuals born small for gestational age have increased risks of serious illness as newborns and throughout life, including hypertension, cardiovascular disease, type 2 diabetes and pregnancy-related hypertension and diabetes...
  30. Pregnancy complications, future cardiovascular disease risk factors and cardiovas
    NISHA INDRAVADAN PARIKH; Fiscal Year: 2013
    ..and CVD include pregnancy- induced hypertension or pre-eclampsia, gestational diabetes, having a small for gestational age infant, a low or very high number of pregnancies, pre-term delivery, stillbirth and a history of subfertility...
  31. Temperature & Vasomotor Tone During the First 5 Days in Preterms Less than 1000g
    ROBIN BRITT KNOBEL; Fiscal Year: 2010
    ..using SAS software, first as case studies within-subjects, then with comparison between subjects in three gestational age groups: 23-25, 25 1/7-27, and 27 1/7-28 6/7 weeks...
  32. Cytokines and the blood-brain barrier in the ovine fetus
    Barbara S Stonestreet; Fiscal Year: 2012
    ..Aim 2 determines whether ischemic injury increases the permeability of the BBB to cytokines as a function of gestational age and tight junction maturation. Brain ischemia is induced by carotid occlusion...
  33. Ophthalmologic Follow-up Care for Children Born Very-Low-Birth-Weight
    CHIHHUNG JASON WANG; Fiscal Year: 2012
    ..The incidence and severity of visual morbidity and disability increase with shorter gestational age and with increasing severity of ROP...
  34. Effects of maternal cortisol on fetal and neonatal growth and metabolism
    Maureen Keller-Wood; Fiscal Year: 2013
    ..Addison's disease, or hyperadrenocorticism, Cushing's syndrome, results in small for gestational age infants...
  35. Artificial Placenta Device
    KATHRYN R OSTERHOLZER; Fiscal Year: 2013
    ..many of these babies recover with conventional management, the mortality and morbidity of extremely low gestational age newborns (ELGANs) defined as born more than 3 months before the expected date of birth, is very high...
  36. Pre-Clinical Development of a Fetal Micropacemaker
    Ramen Chmait; Fiscal Year: 2013
    ..is a life-threatening emergency in a fetus, and is nearly always fatal if hydrops fetalis develops at a young gestational age. There are currently no effective treatment options in these cases, and attempts to implant an extra-uterine ..
  37. Disruption of Neural Stem Cell Homeostasis by Cytomegalovirus
    DEBORAH HYE SPECTOR; Fiscal Year: 2013
    ..It is likely that gestational age an the stage of differentiation of the susceptible neural cells at the time of infection will determin the ..
  38. Atlas - A Handheld High Resolution Wide-field Retinal Imager
    PAUL ANDREW YATES; Fiscal Year: 2013
    ..is a treatable eye disease which affects the vision of neonatal infants with a birth weight of <1500g or gestational age of <30 weeks. There are 28,000 infants born each year in the US at risk for developing ROP...
  39. UNDERSTANDING NEUROBEHAVIORAL DEFICITS IN PRETERM INFANTS THROUGH IMAGING
    David C Van Essen; Fiscal Year: 2012
    ..Approximately 10-15% of very preterm children (born <30 weeks gestational age) develop cerebral palsy, and 30 - 60% of very preterm children experience cognitive impairments...
  40. Prenatal Bisphenol A Exposure and Risk of Gestational Diabetes
    Assiamira Ferrara; Fiscal Year: 2013
    ..a prospective, nested case-control study (cases will be matched to controls on age, race-ethnicity and gestational age at the GDM screening)...
  41. Early Life Nutritional Environments and Cognitive Ability in Children
    Rika Tanda; Fiscal Year: 2012
    ..are more likely to have higher birth weights (large-for-gestational-age, LGA, e90th percentile for weight and gestational age), and are at greater risk for developing obesity, type 2 diabetes (T2DM) and metabolic syndrome in later life...
  42. Pre-existing Diabetes and Pregnancy
    Caitlin A Knox; Fiscal Year: 2013
    ..This linkage to BRCs enriches the MAX billing records with clinical parameters such as gestational age and the comprehensive medical history obtained through parent self-report...
  43. Intervening to Improve Birth Weight and Infant Respiratory Health in Rural Ghana
    PATRICK LOTT KINNEY; Fiscal Year: 2013
    ..b>Gestational age will be determined by sonogram upon enrollment and provide confirmation that potential subjects are carrying ..
  44. Exploring the Fuel-Mediated Programming of Neonatal Growth
    Dana Dabelea; Fiscal Year: 2013
    ..IL-6, TNF-[unreadable]) and insulin resistance (HOMA-IR)], and infant body size (birth weight for gestational age), fatness (determined by air displacement plethysmography) and fat deposition (skinfolds)...
  45. The Infant Development and the Environmental Study (TIDES)
    Shanna H Swan; Fiscal Year: 2013
    ..AGD, PW, testicular volume (TV) and testicular location (TL) in male newborns, specific for birthweight and gestational age. We will examine 1,000 newborn males (including 500 males born to members of the pregnancy cohort and an ..
  46. The Effects of Docosahexaenoic acid (DHA) on fetal cardiac outcomes
    Kathleen M Gustafson; Fiscal Year: 2010
    ..on maternal and fetal cardiac measures of rate and variability and fetal movements at 24 and 36 weeks gestational age. Additionally, we plan a postnatal assessment to determine the effect of supplementation on newborn ..
  47. Impact of TB on Outcome of HIV in Pregnant Women
    Richard E Chaisson; Fiscal Year: 2013
    ..ward at the Chris Hani Baragwanath Hospital and 500 HIV-infected pregnant women without TB matched based on gestational age and site of enrollment...
  48. Factors Determining Bisphenol A Disposition in Human Infants
    D Gail McCarver; Fiscal Year: 2013
    ..in a cross sectional cohort of newborns using a stratified recruitment strategy powered to test the impact of gestational age from 24 to 40 weeks...
  49. Effect of Air Pollution and Traffic on Birth Outcomes
    Michelle L Bell; Fiscal Year: 2012
    ..increased risk for low birth weight (<2500 gm), preterm delivery (<37 weeks gestation) and small for gestational age birth (<10th percentile weight for gestational age)...
  50. Integrative Stress Reduction for Maternal-Child Health
    Larissa G Duncan; Fiscal Year: 2013
    ..stress physiology (neuroendocrine and cardiovascular/ autonomic nervous system function), and birth outcomes (gestational age and birth weight) will be compared...
  51. Birth Outcomes Among Adolescents
    EMILY WHEELER HARVILLE; Fiscal Year: 2012
    ..how individual resources (self-esteem, intelligence, mental health, self- efficacy) affect birth weight and gestational age in adolescent girls;2) To examine how micro system strengths and weaknesses (family closeness, family ..
  52. A Follow-up of Children Enrolled in the Management of Myelomeningocele Study
    ELIZABETH ANN THOM; Fiscal Year: 2013
    ..a singleton fetus with a myelomeningocele lesion starting at T1-S1 with evidence of hindbrain herniation, and gestational age 19-24 weeks are randomized to fetal repair in utero via hysterotomy versus standard postnatal repair for ..
  53. Multiple Chronic Conditions in VLBW Infants: Epidemiology, NICU Care, and Outcome
    William Gardner; Fiscal Year: 2010
    ..Premature and very low birth weight infants (PVLBW, defined as gestational age d 32 weeks and birth weight d 1500g) are 100 times more likely than a normal infant to die in the first year ..
  54. Research on the Scope and Causes of Stillbirth in the US
    Carol Hogue; Fiscal Year: 2009
    ..7 stillbirths per 1,000 deliveries >20 wks). Data on prenatal care, maternal race, gestational age, cause of death are presented and compared to the entire 3-County area, the 5-County area of the Metropolitan ..
  55. Prenatal Exposure to Solid Fuel Smoke and Birth Outcomes in Sri Lanka
    Nalini Sathiakumar; Fiscal Year: 2011
    ..studies are required to confirm the risk estimates, with an emphasis on accurate assessments of exposure and gestational age. In the proposed research, we plan to evaluate the relationship between solid fuel use and birth outcomes and ..
  56. The SAIL trial [Sustained Aeration of Infant Lungs]
    Sarah J Ratcliffe; Fiscal Year: 2013
    ..infants are at high risk of death or BPD, the most vulnerable are those born between 23 and 26 weeks'gestational age (GA). In this population, the rate of death or BPD was 68% in the recent 'SUPPORT'trial...
  57. Gender preference and maternal stress in China
    Kek Khee Loo; Fiscal Year: 2010
    ..Families will be recruited at 15 weeks gestational age (T1), and followed up at: 30 and 36 weeks prenatally, and 3 months post term age (T2, T3 and T4 respectively)...
  58. Preterm Epo Neuroprotection Trial (PENUT Trial) CCC
    Sandra E Juul; Fiscal Year: 2013
    ..These infants, termed Extremely Low Gestational Age Neonates (ELGANs), experience high morbidity and mortality: 20% of ELGANs admitted to an NICU die before ..
  59. Elective Induction of Labor and Pregnancy Outcomes
    Darios Getahun; Fiscal Year: 2013
    ..found more cesarean delivery after induction, but most compared induction to spontaneous labor at the same gestational age, which is not the genuine clinical alternative...
  60. Space-time Modeling for Linking Climate Change,Pollutant Exposure, Built Environm
    Montserrat Fuentes; Fiscal Year: 2013
    ..We will use the statistical frameworks above and data on birth weight and gestational age at delivery in the Pregnancy, Infection, and Nutrition (PIN) study, which examines neighborhood factors ..
  61. Massage to reduce intrauterine artery resistance, prematurity and low birthweight
    MIGUEL ANGEL DIEGO; Fiscal Year: 2012
    ..pressure massage may increase progesterone/estriol ratios which counteract the negative cortical effects on gestational age. Eighty pregnant women with depression symptoms will be recruited at approximately 20 weeks gestation and ..
  62. Fetal Programming and Human Physical Performance
    Tom Brutsaert; Fiscal Year: 2009
    ..n=32) from the distribution of potential male and female subjects in our target population with normal gestational age. This project has relevance for the public health as human physical performance outcomes both affect and are ..
  63. Point-of Care System for Determination of Bilirubin Capacity in Neonates
    GLEN D RAMSAY; Fiscal Year: 2010
    ..for bilirubin associated brain damage, management of neonatal jaundice remains based upon proxies, such as gestational age and birth weight along with the bilirubin level...
  64. Race Related Stressors and Preterm Birth in African American Women
    Carmen Giurgescu; Fiscal Year: 2009
    ..and stress responses between women with preterm birth and women with full term birth when controlling for gestational age at data collection and circadian rhythm;and (6) preliminary evidence of the promise of our theoretical model ..
  65. MOTOR-Maternal Oral Therapy to Reduce Obstetric Risk
    STEVEN NMN OFFENBACHER; Fiscal Year: 2010
    ..g. gestational age (GA)<37 weeks: adjusted odds ratio 2.1(CI95%:1.12, 4.09)and OR=4.2 for GA<28 weeks (CI95%: 1.42,12...
  66. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2006
    ..The two most important factors affecting perinatal mortality are gestational age and relative birth weight; with each additional fetus, both of these factors are compromised...
  67. PARENTAL EMPLOYMENT AND CHILD DEVELOPMENT
    CHRISTOPHER RUHM; Fiscal Year: 2002
    ..pregnancy affect the receipt of prenatal care, other maternal inputs into fetal development, birth weight, gestational age, or infant health? Does parental employment in the early years of the child's life influence the extent and ..
  68. Psychoneuroimmunology: Preterm Birth in Hispanics
    ROBERTA RUIZ; Fiscal Year: 2007
    ..from acculturation through the endocrine and immune systems to decreased infant birth weight and decreased gestational age in Hispanic women...
  69. HYPOTHYROXINEMIA OF PREMATURITY AND NEURODEVELOPMENT
    MARY REUSS; Fiscal Year: 1993
    ..associated with normal or low thyrotropin levels, occurs in 15-80% of premature infants, depending on the gestational age(1-8)...
  70. Hormone markers during pregnancy and ovarian concer risk
    Sven Cnattingius; Fiscal Year: 2005
    ..The levels of pregnancy hormones are influenced by pregnancy characteristics, such as gestational age. Despite the evidence that risk of ovarian cancer is reduced with increasing parity, while incomplete ..
  71. Planning Grant for PRESOX Trial
    Neil Finer; Fiscal Year: 2009
    ..with a low oxygen concentration of 30% (LOWOX) compared to with the use of a 60% (HIOX) for the extremely low gestational age newborn (ELGAN). (Both Fio2 values are to be further discussed during planning period)...
  72. PARENTAL DRINKING, TOXICANT INTERACTIONS, AND PREGNANCY
    David Savitz; Fiscal Year: 1993
    ..to occupational and environmental toxicants, on pregnancy and birth outcomes (stillbirth, birth size, gestational age, intrauterine growth)...
  73. CORRELATES OF PRETERM AND TERM INFANT FEEDING OUTCOMES
    Karen Pridham; Fiscal Year: 1992
    ..status, education, parenting stress, and depressive symptoms) and infant characteristics (maturity at birth-gestational age, respiratory status, and weight) with maternal feeding behavior; and (2) infant characteristics, maternal and ..