growth

Summary

Summary: Gradual increase in the number, the size, and the complexity of cells of an individual. Growth generally results in increase in ORGAN WEIGHT; BODY WEIGHT; and BODY HEIGHT.

Top Publications

  1. ncbi Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version
    Cynthia L Ogden
    National Center for Health Statistics, Hyattsville, Maryland National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Pediatrics 109:45-60. 2002
  2. pmc Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
    Katherine Amps
    Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK
    Nat Biotechnol 29:1132-44. 2011
  3. ncbi Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    JAMA 292:2357-65. 2004
  4. pmc βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism
    Xunshan Ding
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Cell Metab 16:387-93. 2012
  5. pmc Being big or growing fast: systematic review of size and growth in infancy and later obesity
    Janis Baird
    MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton SO16 6YD
    BMJ 331:929. 2005
  6. pmc A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response
    Arnaud Sartelet
    Unit of Animal Genomics, GIGA R, Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    PLoS Genet 8:e1002581. 2012
  7. ncbi A review and meta-analysis of the impact of intestinal worms on child growth and nutrition
    Andrew Hall
    Centre for Public Health Nutrition, University of Westminster, London, UK
    Matern Child Nutr 4:118-236. 2008
  8. ncbi Growth control and ribosome biogenesis
    Harri Lempiäinen
    Department of Molecular Biology and NCCR Program Frontiers in Genetics, University of Geneva, 30 Quai Ernest Ansermet, Geneva 4, Switzerland
    Curr Opin Cell Biol 21:855-63. 2009
  9. ncbi Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis
    Ken K L Ong
    Department of Paediatrics, University of Cambridge, Addenbrookes Hospital, Cambridge, UK
    Pediatr Res 52:863-7. 2002
  10. pmc Small is beautiful: insulin-like growth factors and their role in growth, development, and cancer
    Robert G Maki
    Memorial Sloan Kettering Cancer Center, New York, NY 10065 6007, USA
    J Clin Oncol 28:4985-95. 2010

Detail Information

Publications276 found, 100 shown here

  1. ncbi Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version
    Cynthia L Ogden
    National Center for Health Statistics, Hyattsville, Maryland National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Pediatrics 109:45-60. 2002
    To present a clinical version of the 2000 Centers for Disease Control and Prevention (CDC) growth charts and to compare them with the previous version, the 1977 National Center for Health Statistics (NCHS) growth charts.
  2. pmc Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
    Katherine Amps
    Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK
    Nat Biotechnol 29:1132-44. 2011
    ..21, including three genes expressed in human ES cells, ID1, BCL2L1 and HM13, occurred in >20% of the lines. Of these genes, BCL2L1 is a strong candidate for driving culture adaptation of ES cells...
  3. ncbi Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    JAMA 292:2357-65. 2004
    ..Neonatal infections are frequent complications of extremely low-birth-weight (ELBW) infants receiving intensive care...
  4. pmc βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism
    Xunshan Ding
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Cell Metab 16:387-93. 2012
    Fibroblast growth factor 21 (FGF21) is a fasting-induced hepatokine that has potent pharmacologic effects in mice, which include improving insulin sensitivity and blunting growth...
  5. pmc Being big or growing fast: systematic review of size and growth in infancy and later obesity
    Janis Baird
    MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton SO16 6YD
    BMJ 331:929. 2005
    To assess the association between infant size or growth and subsequent obesity and to determine if any association has been stable over time.
  6. pmc A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response
    Arnaud Sartelet
    Unit of Animal Genomics, GIGA R, Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    PLoS Genet 8:e1002581. 2012
    We report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle (BBC)...
  7. ncbi A review and meta-analysis of the impact of intestinal worms on child growth and nutrition
    Andrew Hall
    Centre for Public Health Nutrition, University of Westminster, London, UK
    Matern Child Nutr 4:118-236. 2008
    ..intestinal worms with particular attention to intestinal nematodes; (2) examines how such worms may affect child growth and nutrition; (3) reviews the biological and epidemiological factors that influence the effects that worms can ..
  8. ncbi Growth control and ribosome biogenesis
    Harri Lempiäinen
    Department of Molecular Biology and NCCR Program Frontiers in Genetics, University of Geneva, 30 Quai Ernest Ansermet, Geneva 4, Switzerland
    Curr Opin Cell Biol 21:855-63. 2009
    Ribosomes provide the basis for protein production and this drives cell growth. Recent studies, both in yeast and in higher eukaryotes, are beginning to reveal new mechanisms underlying the elaborate control of ribosome biogenesis, which ..
  9. ncbi Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis
    Ken K L Ong
    Department of Paediatrics, University of Cambridge, Addenbrookes Hospital, Cambridge, UK
    Pediatr Res 52:863-7. 2002
    There is remarkably wide variation in rates of infancy growth, however, its regulation is not well understood...
  10. pmc Small is beautiful: insulin-like growth factors and their role in growth, development, and cancer
    Robert G Maki
    Memorial Sloan Kettering Cancer Center, New York, NY 10065 6007, USA
    J Clin Oncol 28:4985-95. 2010
    Insulin-like growth factors were discovered more than 50 years ago as mediators of growth hormone that effect growth and differentiation of bone and skeletal muscle...
  11. ncbi Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation
    Lazaros C Foukas
    Ludwig Institute for Cancer Research, 91 Riding House Street, London W1W 7BS, UK
    Nature 441:366-70. 2006
    ..severely blunted signalling via insulin-receptor substrate (IRS) proteins, key mediators of insulin, insulin-like growth factor-1 and leptin action...
  12. pmc Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
    Xiaocheng C Dong
    Howard Hughes Medical Institute, Division of Endocrinology, Children s Hospital Boston, Karp Family Research Laboratories, 300 Longwood Avenue, Harvard Medical School, Boston, MA 02115, USA
    Cell Metab 8:65-76. 2008
    ..mice were small and developed diabetes; analysis of the DKO-liver transcriptome identified perturbed expression of growth and metabolic genes, including increased Ppargc1a and Igfbp1, and decreased glucokinase, Srebp1c, Ghr, and Igf1...
  13. ncbi A general model for ontogenetic growth
    G B West
    Theoretical Division, MS B285, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA
    Nature 413:628-31. 2001
    Several equations have been proposed to describe ontogenetic growth trajectories for organisms justified primarily on the goodness of fit rather than on any biological mechanism...
  14. pmc Fetal and early life growth and body mass index from birth to early adulthood in 1958 British cohort: longitudinal study
    T J Parsons
    Department of Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH, UK
    BMJ 323:1331-5. 2001
    ..mass index at different stages of later life; whether this relation persists after accounting for potential confounding factors; and the role of indicators of fetal growth (birth weight relative to parental size) and childhood growth.
  15. ncbi Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials
    Kenneth H Brown
    Program in International Nutrition and the Department of Nutrition, University of California, Davis 95616, USA
    Am J Clin Nutr 75:1062-71. 2002
    Multiple studies have been carried out to assess the effect of zinc supplementation on children's growth. The results of these studies are inconsistent, and the factors responsible for these varied outcomes are unknown.
  16. ncbi Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration
    Yoonsung Lee
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Development 132:5173-83. 2005
    ..These instructions specify the amount of tissue to regenerate, as well as the rate at which regenerative growth is to occur...
  17. ncbi Rapid growth in infancy and childhood and obesity in later life--a systematic review
    P O A Monteiro
    Department of Clinical Medicine, Federal University of Pelotas, 96001 970 Pelotas, Brazil
    Obes Rev 6:143-54. 2005
    ..This systematic review addresses studies of the role of rapid growth in infancy and childhood as possible determinants of overweight and obesity later in the life course...
  18. ncbi Effectiveness of an educational intervention on complementary feeding practices and growth in rural China: a cluster randomised controlled trial
    Ling Shi
    College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA 02125, USA
    Public Health Nutr 13:556-65. 2010
    ..We developed an educational intervention, delivered by local health-care providers, aimed at improving complementary feeding practices and child nutrition...
  19. pmc Associations of linear growth and relative weight gain during early life with adult health and human capital in countries of low and middle income: findings from five birth cohort studies
    Linda S Adair
    Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516 2524, USA
    Lancet 382:525-34. 2013
    Fast weight gain and linear growth in children in low-income and middle-income countries are associated with enhanced survival and improved cognitive development, but might increase risk of obesity and related adult cardiometabolic ..
  20. pmc Inhibition of growth hormone signaling by the fasting-induced hormone FGF21
    Takeshi Inagaki
    Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Cell Metab 8:77-83. 2008
    Starvation blocks the actions of growth hormone (GH) and inhibits growth through mechanisms that are not well understood...
  21. ncbi Characterizing extreme values of body mass index-for-age by using the 2000 Centers for Disease Control and Prevention growth charts
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    Am J Clin Nutr 90:1314-20. 2009
    The 2000 Centers for Disease Control and Prevention (CDC) growth charts included lambda-mu-sigma (LMS) parameters intended to calculate smoothed percentiles from only the 3rd to the 97th percentile.
  22. pmc The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development
    J Xu
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 97:6379-84. 2000
    ..Hormonal analysis indicates that SRC-3 plays a role in both the growth hormone regulatory pathway and the production of estrogen, which may explain the observed phenotypes...
  23. ncbi Infant growth and later body composition: evidence from the 4-component model
    Sirinuch Chomtho
    The Medical Research Council, Childhood Nutrition Research Centre, Institute of Child Health, University College London, London, United Kingdom
    Am J Clin Nutr 87:1776-84. 2008
    ..Rapid weight gain in infancy is associated with higher body mass index in later life, but its relation with individual body-composition components remains unclear...
  24. ncbi Timing and tempo of first-year rapid growth in relation to cardiovascular and metabolic risk profile in early adulthood
    Ralph W J Leunissen
    Department of Pediatrics, Subdivision of Endocrinology, Erasmus Medical Center Sophia Children s Hospital, 3015 GJ Rotterdam, The Netherlands
    JAMA 301:2234-42. 2009
    b>Growth during infancy appears to be an important determinant of cardiovascular disease and type 2 diabetes later in life.
  25. ncbi Programming of body composition by early growth and nutrition
    Jonathan C K Wells
    Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Proc Nutr Soc 66:423-34. 2007
    There is now compelling evidence that growth patterns in early life are associated with risk of the metabolic syndrome in adulthood, although the relative importance of prenatal v...
  26. ncbi Lifespan: catch-up growth and obesity in male mice
    Susan E Ozanne
    Department of Clinical Biochemistry, University of Cambridge, Cambridge, CB2 2QR, UK
    Nature 427:411-2. 2004
    Poor fetal growth is linked with long-term detrimental effects on health in adulthood...
  27. pmc Antenatal supplementation with folic acid + iron + zinc improves linear growth and reduces peripheral adiposity in school-age children in rural Nepal
    Christine P Stewart
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Clin Nutr 90:132-40. 2009
    ..We previously reported that a randomized controlled trial of antenatal micronutrient supplements in rural Nepal decreased the risk of low birth weight by approximately 15%...
  28. pmc Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth
    Cathy E Elks
    MRC Epidemiology Unit, Addenbrooke s Hospital, Cambridge, United Kingdom
    PLoS Med 7:e1000284. 2010
    ..Exploration of these genotype associations in children may provide insights into the timing of weight changes leading to adult obesity...
  29. pmc Neonatal and fetal exposure to trans-fatty acids retards early growth and adiposity while adversely affecting glucose in mice
    Kylie Kavanagh
    Department of Pathology, Section on Comparative Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Nutr Res 30:418-26. 2010
    ..of C18:1 and then aimed to determine whether maternal transfer of TFAs through pregnancy and lactation alters growth, body composition, and glucose metabolism...
  30. ncbi Cytoskeletal control of growth and cell fate switching
    Akiko Mammoto
    Vascular Biology Program, Department of Surgery, Harvard Medical School and Children s Hospital, Boston, MA 02115, USA
    Curr Opin Cell Biol 21:864-70. 2009
    Living cells must be able to switch between growth and differentiation with high fidelity and precise spatial control to ensure that normal tissue patterns are formed in the embryo and maintained throughout adult life...
  31. pmc Serum dioxins and polychlorinated biphenyls are associated with growth among Russian boys
    Jane S Burns
    Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Ave, Building I, Room 1404E, Boston, MA 02115, USA
    Pediatrics 127:e59-68. 2011
    We evaluated the associations of serum dioxins and polychlorinated biphenyls (PCBs) with longitudinally assessed growth measurements among peripubertal Russian boys.
  32. pmc Growth faltering due to breastfeeding cessation in uninfected children born to HIV-infected mothers in Zambia
    Stephen Arpadi
    Columbia University Gertrude H Sergievsky Center, College of Physicians and Surgeons and Mailman School of Public Health, New York, NY 10030, USA
    Am J Clin Nutr 90:344-53. 2009
    The effect of breastfeeding on growth in HIV-exposed infants is not well described.
  33. ncbi Intrauterine growth restriction as a potential risk factor for disease onset in adulthood
    Anastasia A Varvarigou
    Department of Paediatrics, Neonatal Intensive Care Unit, University of Patras, Medical School, Rio, Patras, Greece
    J Pediatr Endocrinol Metab 23:215-24. 2010
    Intrauterine growth restriction (IUGR) is a risk factor for cardiovascular disease, type 2 diabetes mellitus, and obesity in adulthood...
  34. ncbi The evolution of growth trajectories: what limits growth rate?
    Caitlin M Dmitriew
    Department of Ecology and Evolutionary Biology, University of Toronto, Canada
    Biol Rev Camb Philos Soc 86:97-116. 2011
    According to life-history theory, growth rates are subject to strong directional selection due to reproductive and survival advantages associated with large adult body size...
  35. ncbi Class 2 IGF-1 isoforms are dispensable for viability, growth and maintenance of IGF-1 serum levels
    L Temmerman
    European Molecular Biology Laboratory Mouse Biology Unit, Via Ramarini 32, I 00015 Monterotondo Scalo, Roma, Italy
    Growth Horm IGF Res 20:255-63. 2010
    Insulin-like growth factor 1 (IGF-1) is a pleiotropic factor involved in growth, cell survival and cellular differentiation. It exerts its functions through endocrine, paracrine or autocrine mechanisms...
  36. pmc Effect of in utero and early-life conditions on adult health and disease
    Peter D Gluckman
    Liggins Institute, University of Auckland, and National Research Centre for Growth and Development, Auckland, New Zealand
    N Engl J Med 359:61-73. 2008
  37. ncbi Growth at puberty
    Alan D Rogol
    Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA
    J Adolesc Health 31:192-200. 2002
    Somatic growth and maturation are influenced by a number of factors that act independently or in concert to modify an individual's genetic potential...
  38. ncbi Patterns of growth among children who later develop type 2 diabetes or its risk factors
    J G Eriksson
    National Public Health Institute, Helsinki, Finland
    Diabetologia 49:2853-8. 2006
    We studied fetal and childhood growth patterns that are associated with IGT and type 2 diabetes in adult life.
  39. ncbi Insulin sensitivity and secretion are related to catch-up growth in small-for-gestational-age infants at age 1 year: results from a prospective cohort
    Nestor Soto
    Institute of Maternal and Child Research IDIMI, Faculty of Medicine, University of Chile, Casilla 226 3, Santiago, Chile
    J Clin Endocrinol Metab 88:3645-50. 2003
    ..In addition, SGA infants were stratified according to catch-up growth (CUG) in weight (WCUG) or length (LCUG) during the first year of life...
  40. ncbi Programmed obesity in intrauterine growth-restricted newborns: modulation by newborn nutrition
    Mina Desai
    Perinatal Research Laboratories, Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California Los Angeles, Torrance, CA, USA
    Am J Physiol Regul Integr Comp Physiol 288:R91-6. 2005
    ..programming of appetite-regulating hormones, body composition, and propensity to adult obesity in intrauterine growth-restricted (IUGR) newborns...
  41. pmc Deletion of ghrelin impairs neither growth nor appetite
    Yuxiang Sun
    Department of Molecular and Cellular Biology, Huffington Center on Aging, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Mol Cell Biol 23:7973-81. 2003
    Pharmacological studies show that ghrelin stimulates growth hormone release, appetite, and fat deposition, but ghrelin's physiological role in energy homeostasis has not been established...
  42. ncbi The developmental origins of adult disease
    D J P Barker
    MRC Environmental Epidemiology Unit, Southampton General Hospital, Southampton, UK
    Eur J Epidemiol 18:733-6. 2003
  43. ncbi The thrifty phenotype: An adaptation in growth or metabolism?
    Jonathan C K Wells
    Childhood Nutrition Research Centre, UCL Institute of Child Health, London, UK
    Am J Hum Biol 23:65-75. 2011
    ..is adaptive about early life thrift, and biomedical approaches struggle to explain why associations between early growth and later disease hold across the entire range of birth size...
  44. ncbi Effect of growth on cardiometabolic status at 4 y of age
    Camila Corvalan
    Emory University, Atlanta, GA, USA
    Am J Clin Nutr 90:547-55. 2009
    Cardiovascular disease (CVD) risks are increasingly being diagnosed in children and track into adulthood. Growth is associated with CVD risk in adulthood; however, its contribution to CVD risks in children facing the obesity epidemic is ..
  45. ncbi Cow milk consumption, insulin-like growth factor-I, and human biology: a life history approach
    Andrea S Wiley
    Human Biology Program and Department of Anthropology, Indiana University, Bloomington, Indiana 47405, USA
    Am J Hum Biol 24:130-8. 2012
    ..cow milk consumption at different stages in early life (prenatal to adolescence), especially with regard to linear growth and age at menarche and the role of insulin-like growth factor I (IGF-I) in mediating a relationship among milk, ..
  46. pmc Genome-wide linkage analysis of QTL for growth and body composition employing the PorcineSNP60 BeadChip
    Ana I Fernandez
    Departamento de Mejora Genética Animal, INIA, Ctra, De la Coruña km, 7, Madrid, 28040, Spain
    BMC Genet 13:41. 2012
    ..The aims of the current study are to confirm previous QTL regions for growth and body composition traits in different generations of an Iberian x Landrace intercross (IBMAP) and especially ..
  47. pmc Polygenic risk, rapid childhood growth, and the development of obesity: evidence from a 4-decade longitudinal study
    Daniel W Belsky
    Institute for Genome Sciences and Policy, Duke University, Grey House, Duke University, Durham, NC 27708, USA
    Arch Pediatr Adolesc Med 166:515-21. 2012
    ..To test how genomic loci identified in genome-wide association studies influence the development of obesity...
  48. pmc Use of national and international growth charts for studying height in European children: development of up-to-date European height-for-age charts
    Marjolein Bonthuis
    European Society for Pediatric Nephrology European Renal Association European Dialysis and Transplant Association Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 7:e42506. 2012
    b>Growth charts based on data collected in different populations and time periods are key tools to assess children's linear growth...
  49. ncbi Longevity determined by paternal ancestors' nutrition during their slow growth period
    L O Bygren
    Department of Community Medicine and Rehabilitation, Social Medicine, Umea University, Sweden
    Acta Biotheor 49:53-9. 2001
    ..quot;feedforward" control loop has been proposed, that links grandparental nutrition with the grandchild's growth. The mechanism has been speculated to be a specific response, e.g...
  50. ncbi Dietary nucleotides and early growth in formula-fed infants: a randomized controlled trial
    Atul Singhal
    Institute of Child Health, Medical Research Council Childhood Nutrition Research Center, 30 Guilford St, London WC1N 3EH, United Kingdom
    Pediatrics 126:e946-53. 2010
    ..intake has been suggested to explain some of the benefits of breastfeeding compared with formula feeding and to promote infant growth. However, relatively few large-scale randomized trials have tested this hypothesis in healthy infants.
  51. ncbi Variable degree of growth hormone (GH) and insulin-like growth factor (IGF) sensitivity in children with idiopathic short stature compared with GH-deficient patients: evidence from an IGF-based dosing study of short children
    Pinchas Cohen
    Pediatric Endocrinology, Mattel Children s Hospital at University of California, Los Angeles, 10833 Le Conte Avenue, MDCC 22 315, Los Angeles, California 90095, USA
    J Clin Endocrinol Metab 95:2089-98. 2010
    We recently showed that, in IGF-based GH therapy, the IGF-I target chosen affects GH dose requirements, and higher IGF-I targets are associated with more robust growth parameters.
  52. ncbi Global growth deficiencies in mice lacking the ribosomal protein HIP/RPL29
    Catherine B Kirn-Safran
    Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, USA
    Dev Dyn 236:447-60. 2007
    ..In null embryos, delayed global growth is first observed around mid-gestation, and postnatal lethality due to low birth weight results in distortion of ..
  53. ncbi Early growth patterns and long-term obesity risk
    Nicolas Stettler
    The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Curr Opin Clin Nutr Metab Care 13:294-9. 2010
    This review is an update on recent findings regarding early growth patterns and later obesity...
  54. ncbi Growth of Belgian and Norwegian children compared to the WHO growth standards: prevalence below -2 and above +2 SD and the effect of breastfeeding
    P B Juliusson
    Section for Pediatrics, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway
    Arch Dis Child 96:916-21. 2011
    New national growth references have been published in Belgium and Norway. The WHO recommends universal use of their 2006 Child Growth Standards based on data from breastfed children.
  55. pmc Implications of adopting the WHO 2006 Child Growth Standard in the UK: two prospective cohort studies
    C Wright
    Division of Developmental Medicine, University of Glasgow, Glasgow, UK
    Arch Dis Child 93:566-9. 2008
    The WHO 2006 Child Growth Standard is based on data from international optimally nourished breastfed infants from birth to age 5 years.
  56. pmc Non-compliance with growth hormone treatment in children is common and impairs linear growth
    Wayne S Cutfield
    Liggins Institute, University of Auckland, Auckland, New Zealand
    PLoS ONE 6:e16223. 2011
    GH therapy requires daily injections over many years and compliance can be difficult to sustain. As growth hormone (GH) is expensive, non-compliance is likely to lead to suboptimal growth, at considerable cost...
  57. doi WHO Child Growth Standards in action
    Stef van Buuren
    Netherlands Organization for Applied Scientific Research TNO, Quality of Life, PO Box 2215, 2301 CE Leiden, The Netherlands
    Arch Dis Child 93:549-51. 2008
  58. ncbi The role of infant feeding practices in the explanation for ethnic differences in infant growth: the Amsterdam Born Children and their Development study
    Marieke L A de Hoog
    Department of Public Health, Academic Medical Centre, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Br J Nutr 106:1592-601. 2011
    Rapid early growth in infants may influence overweight and CVD in later life. Both rapid growth and these disease outcomes disproportionately affect some ethnic minorities...
  59. pmc aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues
    Jianqiang Mao
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 106:17576-81. 2009
    ..FACC1KO mice showed prenatal growth retardation; after weaning, however, their weight gain was comparable to that of wild-type (WT) mice on a normal ..
  60. ncbi Growth faltering in rural Gambian infants is associated with impaired small intestinal barrier function, leading to endotoxemia and systemic inflammation
    D I Campbell
    Medical Research Council, Keneba, The Gambia
    J Nutr 133:1332-8. 2003
    b>Growth faltering of rural Gambian infants is associated with a chronic inflammatory enteropathy of the mucosa of the small intestine that may impair both digestive/absorptive and barrier functions...
  61. ncbi Role of obesity and leptin in the pubertal process and pubertal growth--a review
    S Shalitin
    Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Int J Obes Relat Metab Disord 27:869-74. 2003
    ..Children with obesity also have increased adrenal androgen levels, which may be involved in the accelerated growth of these children before puberty...
  62. ncbi Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth
    B E Needham
    Department of Pathology, The University of Melbourne, Victoria 3010, Australia
    J Pathol 215:155-63. 2008
    ..were also significantly reduced in the double knockouts compared to the wild-types, and they showed distinctive growth restriction, suggesting the involvement of a metabolic impairment...
  63. pmc Distinct variants at LIN28B influence growth in height from birth to adulthood
    Elisabeth Widen
    Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland
    Am J Hum Genet 86:773-82. 2010
    We have studied the largely unknown genetic underpinnings of height growth by using a unique resource of longitudinal childhood height data available in Finnish population cohorts...
  64. pmc Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli
    Adam M Feist
    Department of Bioengineering, University of California, 9500 Gilman Drive 0412, San Diego, La Jolla, CA 92093 0412, USA
    Metab Eng 12:173-86. 2010
    ..multiple native products from different representative feedstocks through coupling metabolite production to growth rate...
  65. ncbi Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
    A Nussenzweig
    Department of Medical Physics, Memorial Sloan Kettering Cancer Centre, New York 10021, USA
    Nature 382:551-5. 1996
    ..Consistent with this growth defect, fibroblasts derived from Ku80-/- embryos showed an early loss of proliferating cells, a prolonged doubling ..
  66. ncbi Comparison of the World Health Organization (WHO) Child Growth Standards and the National Center for Health Statistics/WHO international growth reference: implications for child health programmes
    Mercedes de Onis
    Department of Nutrition, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
    Public Health Nutr 9:942-7. 2006
    To compare growth patterns and estimates of malnutrition based on the World Health Organization (WHO) Child Growth Standards ('the WHO standards') and the National Center for Health Statistics (NCHS)/WHO international growth reference ('..
  67. pmc Effects of treatment for intestinal helminth infection on growth and cognitive performance in children: systematic review of randomised trials
    R Dickson
    International Health Division, Liverpool School of Tropical Medicine, Liverpool L3 5QA
    BMJ 320:1697-701. 2000
    To summarise the effects of anthelmintic drug treatment on growth and cognitive performance in children.
  68. ncbi Construction of the World Health Organization child growth standards: selection of methods for attained growth curves
    E Borghi
    Department of Nutrition, WHO, Geneva, Switzerland
    Stat Med 25:247-65. 2006
    ..Organization (WHO), in collaboration with a number of research institutions worldwide, is developing new child growth standards...
  69. ncbi Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
    H Tamemoto
    Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan
    Nature 372:182-6. 1994
    ..homozygous for targeted disruption of the IRS-1 gene were born alive but were retarded in embryonal and postnatal growth. They also had resistance to the glucose-lowering effects of insulin, IGF-1 and IGF-2...
  70. ncbi At the crossroads of growth control; making ribosomal RNA
    Tom Moss
    Cancer Research Centre and Department of Medical Biology, Laval University, Hotel Dieu de Quebec, 9 rue McMahon, G1R 2J6 Québec, Canada
    Curr Opin Genet Dev 14:210-7. 2004
    Although the mechanisms of cell cycle control are well established, the factors controlling cell growth and target size are still poorly understood...
  71. ncbi Progranulin (granulin-epithelin precursor, PC-cell derived growth factor, acrogranin) in proliferation and tumorigenesis
    C H P Ong
    Endocrine Labs, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Histol Histopathol 18:1275-88. 2003
    The granulin-epithelin precursor, progranulin, PC-cell-derived growth factor or acrogranin, is a high molecular weight secreted mitogen...
  72. ncbi Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program
    A Turturro
    Division of Biometry and Risk Assessment, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079 9502, USA
    J Gerontol A Biol Sci Med Sci 54:B492-501. 1999
    ..long-lived rodent models to investigators, while allowing for the development of some of the most definitive information on life span, food consumption, and growth characteristics in these genotypes under diverse feeding paradigms.
  73. ncbi [WHO growth standards for infants and young children]
    M de Onis
    Departement de Nutrition, Organisation mondiale de la Sante, Geneve, Suisse
    Arch Pediatr 16:47-53. 2009
    The growth pattern of healthy breastfed infants deviates to a significant extent from the NCHS/WHO international reference...
  74. ncbi Growth references for Turkish children aged 6 to 18 years
    Olcay Neyzi
    Institute of Environmental Sciences, Bogazici University, Istanbul, Turkey
    Acta Paediatr 95:1635-41. 2006
    To create up-to-date reference standards for Turkish children, and to compare these with growth standards for US children (CDC 2000 Growth Charts) and with previous local data.
  75. pmc Adult height variants affect birth length and growth rate in children
    Lavinia Paternoster
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Hum Mol Genet 20:4069-75. 2011
    ..The age at which these begin to affect growth is unclear. We modelled the effect of these SNPs on birth length and childhood growth...
  76. pmc Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity
    George A Garinis
    MGC Department of Cell Biology and Genetics, Center for Biomedical Genetics, Erasmus Medical Center, PO Box 1738, Rotterdam 3000 DR, The Netherlands
    Nat Cell Biol 11:604-15. 2009
    ..ageing seems to be phenotypically reproducible and regulated through genetic pathways such as the insulin-like growth factor-1 (IGF-1) and growth hormone (GH) receptors, which are central mediators of the somatic growth axis...
  77. ncbi Early diagnosis of cystic fibrosis through neonatal screening prevents severe malnutrition and improves long-term growth. Wisconsin Cystic Fibrosis Neonatal Screening Study Group
    P M Farrell
    University of Wisconsin Medical School, Madison, Wisconsin, USA
    Pediatrics 107:1-13. 2001
    ..In addition, the incidence of CF was determined, and the validity of our randomization method assessed by comparing 16 demographic variables...
  78. ncbi Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis
    Susan R Hintz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA
    Pediatrics 115:696-703. 2005
    ..However, subsequent neurodevelopmental and growth outcomes of extremely low birth weight (ELBW) infants with NEC have not been well described...
  79. pmc Growth patterns of breast fed and formula fed infants in the first 12 months of life: an Italian study
    C Agostoni
    Department of Pediatrics, San Paolo Hospital, University of Milan, 8 Via A di Rudini, 20142 Milan, Italy
    Arch Dis Child 81:395-9. 1999
    To compare the growth patterns of breast fed and formula fed Italian infants in the first 12 months of life using World Health Organisation (WHO) reference data.
  80. ncbi Growth-mortality tradeoffs and 'personality traits' in animals
    Judy A Stamps
    University of California, Davis, Davis, CA 95616, USA
    Ecol Lett 10:355-63. 2007
    ..Here, I suggest that consistent individual differences in growth rates encourage consistent individual differences in behavior patterns that contribute to growth-mortality ..
  81. ncbi Silencing of acetylcholinesterase gene of Helicoverpa armigera by siRNA affects larval growth and its life cycle
    Maneesh Kumar
    Department of Genetics, University of Delhi South Campus, Benito Juarez Road, New Delhi 110021, India
    J Insect Physiol 55:273-8. 2009
    ..The siRNA treatment resulted in specific gene silencing of AChE and consequently brought about mortality, growth inhibition of larvae, reduction in the pupal weight, malformation and drastically reduced fecundity as compared to ..
  82. ncbi Growth and pubertal development in children and adolescents: effects of diet and physical activity
    A D Rogol
    University of Virginia Health Sciences Center Charlottesville, USA
    Am J Clin Nutr 72:521S-8S. 2000
    The longitudinal growth of an individual child is a dynamic statement of the general health of that child. Measurements should be performed often and accurately to detect alterations from physiologic growth...
  83. pmc Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth
    Malene Boas
    Department of Growth and Reproduction, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    Environ Health Perspect 118:1458-64. 2010
    ..Phthalates are widely used chemicals, and human exposure is extensive. Recent studies have indicated that phthalates may have thyroid-disrupting properties...
  84. pmc Quantitative trait loci involved in sex determination and body growth in the gilthead sea bream (Sparus aurata L.) through targeted genome scan
    Dimitrios Loukovitis
    Animal Breeding and Genetics, Department of Animal Production, School of Agricultural Technology, Alexander Technological Institute of Thessaloniki, SINDOS, Greece
    PLoS ONE 6:e16599. 2011
    ..The identification of QTLs linked to sex reversal and growth, will contribute significantly to a better understanding of the complex nature of sex determination in S...
  85. ncbi Parents' growth in childhood and the birth weight of their offspring
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Epidemiology 15:308-16. 2004
    ..We investigated the influence of the childhood growth of the mother or father on the birth weight of their first-born offspring.
  86. ncbi Changes in the use of antimicrobials and the effects on productivity of swine farms in Denmark
    Frank M Aarestrup
    National Food Institute, Technical University of Denmark, Kemitorvet, Building 204, DK 2800, Kongens Lyngby, Denmark
    Am J Vet Res 71:726-33. 2010
    ..To evaluate changes in antimicrobial consumption and productivity by Danish swine farms during 1992 to 2008...
  87. pmc Children of low socioeconomic status show accelerated linear growth in early childhood; results from the Generation R Study
    Lindsay M Silva
    The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    PLoS ONE 7:e37356. 2012
    ..for height development, we hypothesized that a low socioeconomic status is associated with a slower linear growth in early childhood...
  88. ncbi Lipoproteins in Staphylococcus aureus mediate inflammation by TLR2 and iron-dependent growth in vivo
    Mathias Schmaler
    Department of Biomedicine, Division Infection Biology, University Hospital Basel, Basel, Switzerland
    J Immunol 182:7110-8. 2009
    ..inflammation, Lpp allowed bacterial clearing from liver devoid of infiltrating cells, but still conferred a strong growth advantage in mice, which was shown to rely on iron uptake and storage in vitro and in vivo...
  89. pmc Genetic architecture of growth traits revealed by global epistatic interactions
    Lin Xu
    Genome Biol Evol 3:909-14. 2011
    ..13% increase from random expectation) and displays modular architecture among genes that underlie the same growth traits...
  90. ncbi Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmission
    Nelly Briand
    Institut National d Etudes Demographiques, Paris, France
    Pediatr Infect Dis J 25:325-32. 2006
    ..Although reducing substantially the number of infected children, the potential adverse consequences of these treatments on the health of HIV-uninfected children need to be assessed...
  91. ncbi Predictors of children's body mass index: a longitudinal study of diet and growth in children aged 2-8 y
    J D Skinner
    Nutrition Department, University of Tennessee, Knoxville, TN 37996 1920, USA
    Int J Obes Relat Metab Disord 28:476-82. 2004
    ..To identify longitudinal variables related to children's body mass index (BMI) (kg/m(2)) at age 8 y...
  92. ncbi Discontinuation of growth hormone (GH) treatment during the transition phase is an important factor determining the phenotype of young adults with nonidiopathic childhood-onset GH deficiency
    Maria Kołtowska-Häggström
    KIGS KIMS Medical Outcomes, Pfizer Health AB, Endocrine Care, SE 190 91 Sollentuna, Sweden
    J Clin Endocrinol Metab 95:2646-54. 2010
    ..Little is known about the impact of childhood-onset GH deficiency (GHD), in particular the duration of GH cessation during the transition phase, on adult phenotype...
  93. pmc A cluster-randomized controlled trial evaluating the effects of mass azithromycin treatment on growth and nutrition in Niger
    Abdou Amza
    Université Abdou Moumouni de Niamey, Programme National de Lutte Contre la Cecité, Niamey, Niger
    Am J Trop Med Hyg 88:138-43. 2013
    ..There may not be an association between antibiotic use and improved growth in humans, or this trial was not powerful enough to detect an association if it exists.
  94. ncbi The effect of cessation of growth hormone (GH) therapy on bone mineral accretion in GH-deficient adolescents at the completion of linear growth
    W M Drake
    Department of Endocrinology, St Bartholomew s Hospital, London EC1A 7BE, United Kingdom
    J Clin Endocrinol Metab 88:1658-63. 2003
    In many countries, treatment of childhood-onset GH deficiency (GHD) with GH ceases when linear growth is complete. Peak bone mass occurs several years after the completion of linear growth...
  95. ncbi Body size and growth in 0- to 4-year-old children and the relation to body size in primary school age
    T Stocks
    Department of Health Sciences, Faculty of Earth and Life Sciences and EMGO Institute for Health and Care Research, VU University, Amsterdam, The Netherlands
    Obes Rev 12:637-52. 2011
    ..The aim of this study was to review the literature on body size and growth in 0- to 4-year-old children and the association with body size at age 5-13 years...
  96. ncbi Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome
    Lise Aksglaede
    University Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, DK 2100 Copenhagen, Denmark
    J Clin Endocrinol Metab 93:169-76. 2008
    b>Growth is a highly complex process regulated by the interaction between sex steroids and the GH IGF-axis. However, other factors such as sex chromosome-related genes play independent roles.
  97. ncbi Differences in size at birth are determined by differences in growth velocity during early prenatal life
    Silvano Milani
    Istituto di Statistica Medica e Biometria, Universita degli Studi di Milano, Milano, Italy
    Pediatr Res 57:205-10. 2005
    ..interindividual differences in neonatal size are traditionally thought of as determined by differences in fetal growth occurring only in the second half of pregnancy...
  98. ncbi Physical growth assessment in adolescence
    K N Agarwal
    Department of Pediatrics, University College of Medical Sciences, Delhi 110 057, India
    Indian Pediatr 38:1217-35. 2001
    ..To describe ponderosity indices body mass index--"BMI" and ponderal index "PI" and skin fold thicknesses (triceps, biceps, subscapular and suprailiac) for affluent Indian school going adolescents...
  99. ncbi Adolescent growth and development
    Bonnie A Spear
    University of Alabama at Birmingham, 35233, USA
    J Am Diet Assoc 102:S23-9. 2002
  100. ncbi Genetic conflict, genomic imprinting and establishment of the epigenotype in relation to growth
    T Moore
    Department of Biochemistry, University College Cork, Lee Maltings, Prospect Row, Cork, Ireland
    Reproduction 122:185-93. 2001
    ..and their deregulation is implicated in a variety of pathologies including sporadic, inherited and induced growth disorders...
  101. ncbi Assessment of growth
    Timothy James Cole
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guildford Street, London, WC1N 1EH, UK
    Best Pract Res Clin Endocrinol Metab 16:383-98. 2002
    The assessment of growth is an important part of paediatrics and community child health. Poor growth is a common side-effect of many local and systemic conditions and its identification acts as a useful early warning of a possible problem...

Research Grants68

  1. Effect of Health on Education & Work in Filipino Youth
    Linda Adair; Fiscal Year: 2005
    ..characteristics, diet and nutritional status, infectious disease morbidity, preventive health care, early child growth, cognitive ability, and psychological well being...
  2. Prenatal Nutrition and Adverse Birth Outcomes in HIV-Infected Women in Malawi
    Linda Adair; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  3. Obesity development and CVD risk factor clustering in Filipino women & offspring
    Linda Adair; Fiscal Year: 2009
    ....
  4. Impact of Development on Protein Utilization and Growth
    William Heird; Fiscal Year: 2007
    ..While the consequences of the early growth failure are not known with certainty, there is evidence that it may contribute to the high prevalence of ..
  5. DIETARY OMEGA-3 FATTY ACIDS, GENE EXPRESSION AND GROWTH
    William Heird; Fiscal Year: 2001
    ..abstract_text> ..
  6. IMMUNE MECHANISMS OF MIDDLE EAR DISEASE
    David Skoner; Fiscal Year: 2006
    ..The primary hypothesis is that cytokine genotype is predictive of illness expression and of OM incidence during a documented RSV infection in young children. ..
  7. RESEARCH TRAINING IN MATERNAL, INFANT & CHILD NUTRITION
    William Heird; Fiscal Year: 2008
    ..abstract_text> ..
  8. Toddler Feeding Styles
    Maureen M Black; Fiscal Year: 2010
    ..Although caregiver-child interaction patterns influence children's growth and behavior, most overweight prevention programs have focused exclusively on diet and physical activity, with ..
  9. ZINC AND IRON SUPPLEMENTATION: IMPACT ON DEVELOPMENT
    Maureen Black; Fiscal Year: 2002
    The proposed project builds on an existing trial of micronutrient supplementation on children's growth, immune functioning, and morbidity, administered from birth through 9 months among full-term infants born small-for-gestational age in ..
  10. Prenatal Drug Exposure: Effects on Adolescent Brain and Behavioral Development
    Maureen Black; Fiscal Year: 2009
    ..This application examines adacemic performance, socio-emotional functioning, and drug use among adolescents exposed to cocaine and/or heroin prenatally ..
  11. IRON STATUS IN WOMEN OF REPRODUCTIVE AGE
    Usha Ramakrishnan; Fiscal Year: 2002
    ..The investigators state that in summary, the project is expected to provide information that can be used to examine policy options and develop guidelines to ensure adequate but safe iron status for women of reproductive age. ..
  12. DIETARY LIPIDS AND EXPERIMENTAL IGA NEPHROPATHY
    James Pestka; Fiscal Year: 2009
    ..abstract_text> ..
  13. Searching for ADHD Susceptibility Genes
    Stephen V Faraone; Fiscal Year: 2010
    ..That, in turn, should facilitate the search for newer, more effective treatments for the disorder. ..
  14. IGF-I: A Nutrition-Regulated Target in Prostate Cancer
    Pinchas Cohen; Fiscal Year: 2007
    ..Insulin-like growth factor-I (IGF-I) is a potent mitogen that has been implicated as a critical factor in the development of CaP...
  15. FAS Prevention: A Trial of the IOM Model
    Philip May; Fiscal Year: 2009
    ..Selective and universal prevention use: screening for alcohol abuse;targeted messages to change norms and KABB;policy advocacy;and community education and dialogue. ..
  16. Computational Applications in Diabetes and Endocrinology
    Michael Johnson; Fiscal Year: 2007
    ..Eventually, we plan to offer formal degree subspecializations in Biomathematics (BS/MS) and Computational Diabetes and Endocrinology (MS/PhD) [unreadable] [unreadable]..
  17. Growth Outcomes in Bronchopulmonary Dysplasia at 36 Weeks Postconceptional Age
    Deborah Steward; Fiscal Year: 2007
    ..Poor growth is the most common morbidity experienced by VLBW infants with BPD...
  18. Primary Care Obesity Prevention: One or Multiple Targets
    Nicolas Stettler; Fiscal Year: 2010
    ..abstract_text> ..
  19. Vitamins, Breast Milk HIV Shedding and Child Health
    Eduardo Villamor; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  20. Bioactivity and Vitamins in Flash-heated Breastmilk
    Caroline Chantry; Fiscal Year: 2005
    ..Heated milk must be nutritious enough to support growth and development, retain anti-infective activity in order to prevent infectious morbidities...
  21. Validating Novel Familial Phenotypes of Drug Abuse
    Stephen Faraone; Fiscal Year: 2007
    ..State of the art statistical techniques will be employed. ..
  22. Analysis of an ADHD Whole Genome Association Scan
    Stephen Faraone; Fiscal Year: 2007
    ..All genotype data generated by the GAIN whole genome association scan will be made available to the scientific community by GAIN as soon as the genotypes are completed. [unreadable] [unreadable] [unreadable]..
  23. Early Diagnosis of Neonatal Candidiasis
    Daniel Benjamin; Fiscal Year: 2008
    ..abstract_text> ..
  24. EVOLUTION OF BRAIN-BEHAVIOR CONTROLLING MECHANISMS
    David Crews; Fiscal Year: 2009
    ..abstract_text> ..
  25. Feasibility and Pilot Efficacy of Flash-heated Breastmilk to Reduce Pediatric HIV
    Caroline Chantry; Fiscal Year: 2008
    ..4) To pilot an efficacy trial of FH to improve infant health outcomes. Clinic assistants will monitor infant growth and morbidity during home visits twice monthly...
  26. 2/5-The Psychiatric GWAS Consortium: Integrated & Coordinated GWAS Meta-Analyses
    Stephen Faraone; Fiscal Year: 2008
    ..Finally, the PGC proposes to abide as fully as possible with the NIH's GWAS data sharing policies and we provide a detailed data sharing plan and timetable. [unreadable] [unreadable] [unreadable]..
  27. Software For The Analysis Of Hormone Pulsatility
    Michael Johnson; Fiscal Year: 2008
    ..We also envision potential applications in other non-endocrine research fields. ..
  28. Trial of FAS Prevention and Diagnosis Among Indians
    Philip May; Fiscal Year: 2008
    ..The proposed renewal will ensure sufficient time to test the IOM model of prevention while advancing science in several other ways. ..
  29. Increasing youth physical activity: neighborhood environmen influences
    JAMES ROEMMICH; Fiscal Year: 2009
    ..We hypothesize that there will be a main effect of reduction in access to sedentary behaviors on energy and fat intake and percent overweight. ..
  30. Anisotropy and Nonlinearity of Cartilage Mechanics
    Gerard Ateshian; Fiscal Year: 2008
    ..abstract_text> ..
  31. Nutritional and Hormonal Determinants of Peak Bone Mass
    Madhusmita Misra; Fiscal Year: 2008
    ..Calcium and vitamin D supplementation does not improve BMD in AN. Adults with AN have have high growth hormone (GH) and low IGF-I levels, suggestive of a nutritionally acquired 'GH resistance'...
  32. The Role of IGF2 in Fetal Growth Restriction
    Pinchas Cohen; Fiscal Year: 2008
    Fetal growth is a complex process involving multiple environmental and genetic factors...
  33. International Neuropsychological Study of FASD--U01
    Philip May; Fiscal Year: 2005
    ..abstract_text> ..
  34. REGULATION OF SKELETAL GROWTH IN RENAL FAILURE
    CHERYL SANCHEZ; Fiscal Year: 2003
    b>Growth retardation occurs invariably in children with chronic renal failure; secondary hyperparathyroidism and tissue resistance to the actions of IGF-1 are major contributors to impaired growth...
  35. Clinical Predictors of Antiretroviral Failure
    Daniel Benjamin; Fiscal Year: 2003
    ..This proposal will be an important first step to determine if a combination of clinical parameters (age, gender, growth-velocity, and ethnicity) can predict relevant laboratory surrogate markers, clinical outcomes and ART failure...
  36. TESTING THE VALIDITY OF ADULT ATTENTION DEFICIT DISORDER
    Stephen Faraone; Fiscal Year: 2002
    ..Thus, if founded, we expect that the proposed work will lead to a program of research that can both clarify the nosological complexities of adult ADHD and clarify the nature of genes that are risk factors for the disorder. ..
  37. REGULATORY MECHANISMS OF GROWTH-PLATE CHONDROCYTES
    Robert Olney; Fiscal Year: 2002
    There is a gap in the field of growth research. There is a large body of work on growth on the whole body level in humans. There is also a large and rapidly growing body of work on growth-plate regulation in animals...
  38. ENVIRONMENTAL INFLUENCES ON BRAIN PLASTICITY
    David Crews; Fiscal Year: 2002
    ..The final category of experiments is particularly important as it will discern whether the incubation temperature effects are direct or indirect. ..
  39. WHO MULTICENTER GROWTH REFERENCE STUDY: U.S. SITE
    Kathryn Dewey; Fiscal Year: 2002
    Assessment of infant/child growth is a key element of monitoring nutritional status and evaluating the impact of various programs...
  40. ENDOTOXIN AND SUSCEPTIBILITY TO TRICHOTHECENE MYCOTOXINS
    James Pestka; Fiscal Year: 2002
    ..Over the long term, this research will provide insight into adverse immunologic consequences that may occur in LPS-exposed individuals who are exposed to environmental toxicants." ..
  41. IGF AXIS IN ASTHMA
    Pinchas Cohen; Fiscal Year: 2002
    ..b>Growth factors are likely to be involved in the pathogenesis of the ASM hyperplasia in asthma...
  42. TRIAL OF FAS PREVENTION IN AMERICAN INDIAN COMMUNITIES
    Philip May; Fiscal Year: 2001
    ..Furthermore, prevention protocols, research techniques and methods, will test the recommendations of the IOM report and should also be applicable to non-Indian communities as well. ..
  43. MISSING DATA, MEASUREMENT ERROR AND APPLICATIONS
    Ching Yun Wang; Fiscal Year: 2002
    ..The investigator states that the proposed methods will also accommodate two-stage designs which are becoming popular in epidemiologic research and particular in genetic epidemiology. ..
  44. TRAINING PROGRAM IN NEUROBIOLOGY AND BEHAVIOR
    David Crews; Fiscal Year: 2003
    ..All of the laboratories comply with NIH requirements. ..
  45. AN ECOGENETIC STUDY OF ADHD
    Stephen Faraone; Fiscal Year: 2003
    ..Furthermore, no studies have used an ecogenetic approach to sharpen the accuracy of risk prediction. ..
  46. Causal Effects of Schooling on Adult and Child Health
    JERE BEHRMAN; Fiscal Year: 2005
    ..abstract_text> ..
  47. Filipino Early Childhood Development--Longitudinal Anal*
    JERE BEHRMAN; Fiscal Year: 2005
    ..3) To strengthen the analytical capacity of OPS through collaborative analytical research that integrates health, nutrition, demographic and economic concerns, in addition to collaborative data collection. ..
  48. Increasing physical activity of sedentary youth
    JAMES ROEMMICH; Fiscal Year: 2005
    ..This study will yield important information on new ways to increase the physical activity of children. ..
  49. Neurodevelopmental Outcome in Russian Orphanage
    Laurie Miller; Fiscal Year: 2004
    ..have multiple risk factors at birth, including prenatal drug and alcohol exposure, prematurity, intrauterine growth retardation, congenital microcephaly, and lack of prenatal care...
  50. Genomic and Non-Genomic Effects of IGFBP-3 on Apoptosis
    Pinchas Cohen; Fiscal Year: 2004
    ..of the IGF axis in general, and IGFBP-3 in particular, are important determinants of prostate cancer (CaP) cell growth and death, and represent epidemiological risk factors for this disease...
  51. International Multi-Center ADHD Genetics Project
    Stephen Faraone; Fiscal Year: 2007
    ..abstract_text> ..
  52. Epigenetic Influences on Brain and Behavior
    David Crews; Fiscal Year: 2004
    ..Specific Aim III. To establish if the different behavioral profiles exhibited in such animals in adulthood are reflected in different patterns of activity in a network of interconnected limbic nuclei. ..
  53. Mentored Patient-Oriented Research Career Development Aw
    Nicolas Stettler; Fiscal Year: 2005
    ..at the Children's CHOP, and will acquire proficiency with the techniques for the assessment of body composition, growth and energy balance. Drs. Babette S. Zemel at CHOP, and Michael I...
  54. Low Magnitude Mechanical Stimuli Effects on Bone Structu
    Mary Leonard; Fiscal Year: 2006
    ..Consistent with the Program Announcement, it is anticipated that this innovative study will lead to a full-scale clinical trial of LMMS as an anabolic bone therapy for ROD in dialysis patients. ..
  55. Zn & Maternal-Infant Brain Function in S. Ethiopia: Randomized Controlled Trials
    K Hambidge; Fiscal Year: 2009
    ..zinc (Zn) supplementation on: maternal-infant cognition, temperament and bonding and on pre-and post-natal brain growth. The proposal includes further development of research resources at Debub University...
  56. HEALTH EFFECTS OF ACUTE H PYLORI INFECTION IN CHILDREN
    Douglas Passaro; Fiscal Year: 2003
    ..pylori infection is accompanied by gastrointestinal symptoms and to determine whether H.pylori infection leads to growth retardation or increases in diarrheal illness...
  57. Prolactin and Estrogens as Mitogens in Prostate Cancer
    Nira Ben Jonathan; Fiscal Year: 2002
    ..positive regulators of PRL, or by drugs result in rodent prostatic hyperplasia and enhanced rodent prostatic tumor growth. In rodents, hyperprolactinemia and prostatic hyperplasia are also induced by bisphenol A (BPA), an environmental ..
  58. Bone Health in Pediatric Crohn Disease: A Low Magnitude Mechanical Stimulus Trial
    MARY BETH LEONARD; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Skeletal growth is characterized by gender-, maturation-, and race- specific increases in cortical dimensions and trabecular volumetric bone mineral density (vBMD)...
  59. ADJUNCT VITAMIN A THERAPY FOR TUBERCULOSIS AND HIV/AIDS
    Richard Semba; Fiscal Year: 2005
    ....
  60. Imprinted SnoRNA Genes in the PWS deletion Region
    Uta Francke; Fiscal Year: 2005
    ..pathophysiologic pathways that lead to the PWS phenotype that involves metabolic and behavioral changes such as growth deficiency and lack of appetite control...
  61. Antenatal and preschool iron and zinc use and cognition
    Parul Christian; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  62. Great Plains Cultural Ways Mental Health Careers Program
    LESLIE WHITBECK; Fiscal Year: 2008
    ..The proposed program meets a critical need for preparing native undergraduates for careers in mental health research. ..
  63. Iron and the Breast-fed Infant
    Ekhard Ziegler; Fiscal Year: 2005
    ..Iron stores present at birth provide all the iron the normal infant needs for growth during the first 5-6 months of life...
  64. Prevention of Vitamin D Deficiency in Breastfed Infants
    Ekhard Ziegler; Fiscal Year: 2009
    ..The study has considerable public health importance because of the importance of preventing vitamin D deficiency not only in its severe form, rickets, but also in its milder forms. ..
  65. Innovative Modeling of Puberty and Substance Use Risk
    Bin Huang; Fiscal Year: 2009
    ..It will also contribute to the statistical literature on modeling longitudinal pubertal maturational process and complex mediating mechanisms. ..
  66. PARENTING AND INFANT DEVELOPMENT IN ALCOHOLIC FAMILIES
    RINA EIDEN; Fiscal Year: 2009
    ..abstract_text> ..