ventilation

Summary

Summary: Supplying a building or house, their rooms and corridors, with fresh air. The controlling of the environment thus may be in public or domestic sites and in medical or non-medical locales. (From Dorland, 28th ed)

Top Publications

  1. ncbi The relative efficacy of respirators and room ventilation in preventing occupational tuberculosis
    K P Fennelly
    National Jewish Medical and Research Center and the University of Colorado Health Sciences Center, Denver 80206, USA
    Infect Control Hosp Epidemiol 19:754-9. 1998
  2. ncbi Environmental controls in operating theatres
    S Dharan
    Infection Control Programme, Department of Internal Medicine, University of Geneva Hospitals, Switzerland
    J Hosp Infect 51:79-84. 2002
  3. ncbi Ventilation in motor neuron disease: difficult decisions in difficult circumstances
    David Oliver
    Wisdom Hospice, High Bank, Rochester, Kent ME1 2NU, UK
    Amyotroph Lateral Scler Other Motor Neuron Disord 5:6-8. 2004
  4. ncbi On the history of indoor air quality and health
    J Sundell
    International Center for Indoor Environment and Energy, Technical University of Denmark, Lyngby, Denmark
    Indoor Air 14:51-8. 2004
  5. ncbi Sick building syndrome and perceived indoor environment in relation to energy saving by reduced ventilation flow during heating season: a 1 year intervention study in dwellings
    K Engvall
    Stockholm Office of Research and Statistics, Stockholm, Sweden
    Indoor Air 15:120-6. 2005
  6. ncbi Indoor air pollution in developing countries: recommendations for research
    K R Smith
    140 Warren Hall, University of California, Berkeley, California 94720 7360, USA
    Indoor Air 12:198-207. 2002
  7. pmc The characterization of upper-room ultraviolet germicidal irradiation in inactivating airborne microorganisms
    Gwangpyo Ko
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115 6021, USA
    Environ Health Perspect 110:95-101. 2002
  8. doi Roles of sunlight and natural ventilation for controlling infection: historical and current perspectives
    R A Hobday
    Department of Microbiology, Hairmyres Hospital, East Kilbride, Lanarkshire G75 8RG, UK
    J Hosp Infect 84:271-82. 2013
  9. ncbi Ventilation in public housing: implications for indoor nitrogen dioxide concentrations
    A Zota
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA
    Indoor Air 15:393-401. 2005
  10. doi An experimental study on effects of increased ventilation flow on students' perception of indoor environment in computer classrooms
    D Norback
    Medical Science Occupational and Environmental Medicine, and Department of Medical Science, University Hospital Uppsala, Uppsala, Sweden
    Indoor Air 18:293-300. 2008

Detail Information

Publications315 found, 100 shown here

  1. ncbi The relative efficacy of respirators and room ventilation in preventing occupational tuberculosis
    K P Fennelly
    National Jewish Medical and Research Center and the University of Colorado Health Sciences Center, Denver 80206, USA
    Infect Control Hosp Epidemiol 19:754-9. 1998
    To evaluate the relative efficacy of personal respiratory protection as the concentrations of infectious aerosols increase or as room ventilation rates decrease.
  2. ncbi Environmental controls in operating theatres
    S Dharan
    Infection Control Programme, Department of Internal Medicine, University of Geneva Hospitals, Switzerland
    J Hosp Infect 51:79-84. 2002
    ..Modern operating theatres have conventional plenum ventilation with filtered air where particles >/=5 microm are removed...
  3. ncbi Ventilation in motor neuron disease: difficult decisions in difficult circumstances
    David Oliver
    Wisdom Hospice, High Bank, Rochester, Kent ME1 2NU, UK
    Amyotroph Lateral Scler Other Motor Neuron Disord 5:6-8. 2004
    ..A case is presented of a patient who asked for invasive ventilation to be withdrawn and the problems for all involved--patient, family and professionals--are explored...
  4. ncbi On the history of indoor air quality and health
    J Sundell
    International Center for Indoor Environment and Energy, Technical University of Denmark, Lyngby, Denmark
    Indoor Air 14:51-8. 2004
    ..Allergies, airway infections and sick building syndrome are associated with, e.g., "dampness", a low ventilation rate, and plasticizers. In the future more emphasis must be given to IAQ and health issues.
  5. ncbi Sick building syndrome and perceived indoor environment in relation to energy saving by reduced ventilation flow during heating season: a 1 year intervention study in dwellings
    K Engvall
    Stockholm Office of Research and Statistics, Stockholm, Sweden
    Indoor Air 15:120-6. 2005
    b>Ventilation in Scandinavian buildings is commonly performed by means of a constant flow ventilation fan. By using a regulated fan, it is possible to make a seasonal adjustment of outdoor ventilation flow...
  6. ncbi Indoor air pollution in developing countries: recommendations for research
    K R Smith
    140 Warren Hall, University of California, Berkeley, California 94720 7360, USA
    Indoor Air 12:198-207. 2002
    ..national level surveys; (3) interventions: engineering and dissemination approaches for improved stoves, fuels, ventilation, and behavior that reliably and economically reduce exposure...
  7. pmc The characterization of upper-room ultraviolet germicidal irradiation in inactivating airborne microorganisms
    Gwangpyo Ko
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115 6021, USA
    Environ Health Perspect 110:95-101. 2002
    ..Our results indicated that the equivalent ventilation rate attributable to upper-room UVGI for BCG aerosols ranged from 1 ACH to 22 ACH for ceiling-mounted UV ..
  8. doi Roles of sunlight and natural ventilation for controlling infection: historical and current perspectives
    R A Hobday
    Department of Microbiology, Hairmyres Hospital, East Kilbride, Lanarkshire G75 8RG, UK
    J Hosp Infect 84:271-82. 2013
    ..Infections caught in buildings are a major global cause of sickness and mortality. Understanding how infections spread is pivotal to public health yet current knowledge of indoor transmission remains poor...
  9. ncbi Ventilation in public housing: implications for indoor nitrogen dioxide concentrations
    A Zota
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA
    Indoor Air 15:393-401. 2005
    ..Indoor NO2 levels in this cohort are higher than those generally reported in residential US settings, associated in part with increased gas stove usage and decreased AERs during the heating season...
  10. doi An experimental study on effects of increased ventilation flow on students' perception of indoor environment in computer classrooms
    D Norback
    Medical Science Occupational and Environmental Medicine, and Department of Medical Science, University Hospital Uppsala, Uppsala, Sweden
    Indoor Air 18:293-300. 2008
    The effects of ventilation in computer classrooms were studied with university students (n = 355) in a blinded study, 31% were women and 3.8% had asthma. Two classrooms had a higher air exchange (4.1-5...
  11. ncbi Reduction potential of urban PM2.5 mortality risk using modern ventilation systems in buildings
    O O Hänninen
    KTL, Centre for Environmental Health Risk Analysis, Kuopio, Finland
    Indoor Air 15:246-56. 2005
    ..The large fraction of time spent indoors makes the reduction larger than what probably can be achieved by local transport policies or other emission controls in the near future...
  12. doi Effects of intermittent hypoxia on erythropoietin, soluble erythropoietin receptor and ventilation in humans
    J V Brugniaux
    Dept of Physiology and Pharmacology, University of Calgary, Calgary, Canada
    Eur Respir J 37:880-7. 2011
    ..Following exposure to IH, tidal volume (V(T)) increased, respiratory frequency remained unchanged, and minute ventilation (V'(E)) was increased. There was a negative correlation between EPO and sEPOR (r = -0.261; p = 0...
  13. ncbi Exposure to indoor air pollution from household energy use in rural China: the interactions of technology, behavior, and knowledge in health risk management
    Yinlong Jin
    Institute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention CDC, Beijing, PR China
    Soc Sci Med 62:3161-76. 2006
    ..Based on the analysis, we present technological and behavioral interventions for these four Chinese provinces...
  14. ncbi Do indoor pollutants and thermal conditions in schools influence student performance? A critical review of the literature
    M J Mendell
    Lawrence Berkeley National Laboratory, Environmental Energy Technologies Division, Indoor Environment Department, Berkeley, CA 94720, USA
    Indoor Air 15:27-52. 2005
    ..links higher indoor concentrations of NO(2) to reduced school attendance, and suggestive evidence links low ventilation rates to reduced performance...
  15. ncbi Role of ventilation in airborne transmission of infectious agents in the built environment - a multidisciplinary systematic review
    Y Li
    Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, Hong Kong
    Indoor Air 17:2-18. 2007
    ..recent studies demonstrating a definitive association between the transmission of airborne infections and the ventilation of buildings...
  16. doi Ventilation rates and health: multidisciplinary review of the scientific literature
    J Sundell
    Technical University of Denmark, Lyngby, Denmark
    Indoor Air 21:191-204. 2011
    The scientific literature through 2005 on the effects of ventilation rates on health in indoor environments has been reviewed by a multidisciplinary group...
  17. doi The effect of dornase alfa on ventilation inhomogeneity in patients with cystic fibrosis
    R Amin
    Division of Respiratory Medicine, Dept of Paediatrics, The Hospital for Sick Children, Toronto, ON, Canada
    Eur Respir J 37:806-12. 2011
    ..1% ± 10.34%; p = 0.03 and 0.28 ± 0.46 z-score; p = 0.03). Dornase alfa significantly improved LCI. Therefore the LCI may be a suitable tool to assess early intervention strategies in this patient population...
  18. pmc Human occupancy as a source of indoor airborne bacteria
    Denina Hospodsky
    Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut, United States of America
    PLoS ONE 7:e34867. 2012
    ..genome concentration, and bacterial phylogenetic populations were characterized in indoor, outdoor, and ventilation duct supply air, as well as in the dust of ventilation system filters and in floor dust...
  19. pmc The impact of school building conditions on student absenteeism in Upstate New York
    Elinor Simons
    Bureau of Environmental and Occupational Epidemiology, New York State Department of Health, Troy, NY, USA
    Am J Public Health 100:1679-86. 2010
    ..We investigated Upstate New York school building conditions and examined the associations between school absenteeism and building condition problems...
  20. pmc Personalized ventilation as a control measure for airborne transmissible disease spread
    Jovan Pantelic
    Department of Building, School and Design and Environment, National University of Singapore, Singapore, Singapore
    J R Soc Interface 6:S715-26. 2009
    The protective role of personalized ventilation (PV) against plausible airborne transmissible disease was investigated using cough droplets released from a 'coughing machine' simulating the human cough at different distances (1, 1...
  21. ncbi MR-compatible ventilator for small animals: computer-controlled ventilation for proton and noble gas imaging
    L W Hedlund
    Center for In Vivo Microscopy, Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
    Magn Reson Imaging 18:753-9. 2000
    ..endotracheal tube to reduce dead volume and allows independent control of inspiratory and expiratory phases of ventilation. This ventilator has been used in a wide variety of MR and x-ray microscopy studies of small animals, ..
  22. ncbi A probabilistic transmission dynamic model to assess indoor airborne infection risks
    Chung Min Liao
    Ecotoxicological Modeling Center, Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, Taiwan 10617, ROC
    Risk Anal 25:1097-107. 2005
    ..Here, we show that virulence of the organism factors, infectious quantum generation rates (quanta/s by an infected person), and host factors determine the risk for inhalation of indoor airborne infection...
  23. doi Early initiation of basic resuscitation interventions including face mask ventilation may reduce birth asphyxia related mortality in low-income countries: a prospective descriptive observational study
    Hege Langli Ersdal
    Department of Anaesthesiology and Intensive Care, Stavanger University Hospital, Norway
    Resuscitation 83:869-73. 2012
    ..The objectives were to describe normal transitional respiratory adaption at birth and to assess the importance of initiating basic resuscitation within the first minutes after birth as it relates to neonatal outcome...
  24. ncbi Indoor air quality for poor families: new evidence from Bangladesh
    S DasGupta
    Development Research Group, World Bank, Washington, DC 20433, USA
    Indoor Air 16:426-44. 2006
    ..in Dhaka and Narayanganj, with a particular focus on fuel use, cooking locations, structural materials, ventilation practices, and other potential determinants of exposure to IAP...
  25. pmc Airborne transmission of disease in hospitals
    I Eames
    University College London, Gower Street, London WC1E 7JE, UK
    J R Soc Interface 6:S697-702. 2009
    ..The review also points out some of the outstanding scientific questions and possible approaches to mitigating transmission...
  26. pmc The airborne metagenome in an indoor urban environment
    Susannah G Tringe
    Department of Energy Joint Genome Institute, Walnut Creek, California, United States of America
    PLoS ONE 3:e1862. 2008
    ..This baseline index of air microbiota will be valuable for improving designs of surveillance for natural or man-made release of virulent pathogens...
  27. ncbi Indoor air quality, ventilation and health symptoms in schools: an analysis of existing information
    J M Daisey
    Indoor Environment Department, Berkeley, CA 94720, USA
    Indoor Air 13:53-64. 2003
    We reviewed the literature on Indoor Air Quality (IAQ), ventilation, and building-related health problems in schools and identified commonly reported building-related health symptoms involving schools until 1999...
  28. doi Revisiting the effect of room size and general ventilation on the relationship between near- and far-field air concentrations
    John W Cherrie
    Institute of Occupational Medicine, Research Avenue North, Edinburgh EH14 4AP, UK
    Ann Occup Hyg 55:1006-15. 2011
    ..The Advanced REACH Tool (ART) is based on a two-zone dispersion paradigm. Further simulations have been carried out to help ensure that the ART realistically reflects pollutant dispersion...
  29. ncbi A preliminary study on the association between ventilation rates in classrooms and student performance
    R J Shaughnessy
    Indoor Air Program, The University of Tulsa, Tulsa, OK 74104, USA
    Indoor Air 16:465-8. 2006
    ..to students on a yearly basis, to classroom carbon dioxide (CO2) concentrations, which provide a surrogate of ventilation being provided to each room...
  30. ncbi The effect of ventilation strategies of child care centers on indoor air quality and respiratory health of children in Singapore
    M S Zuraimi
    Department of Building, School of Design and Environment, National University of Singapore, Singapore
    Indoor Air 17:317-27. 2007
    This paper reports the effects of ventilation strategies on indoor air quality (IAQ) and respiratory health of children within 104 child care centers (CCCs) in a hot and humid climate...
  31. ncbi Impact of environmental factors on efficacy of upper-room air ultraviolet germicidal irradiation for inactivating airborne mycobacteria
    Peng Xu
    Department of Civil, Environmental, and Architectural Engineering, 428 UCB, University of Colorado, Boulder, Colorado 80309 0428, USA
    Environ Sci Technol 39:9656-64. 2005
    ..W all lamps operating) was operated at 24 and 34 degrees C, between 25 and 90% relative humidity, and at three ventilation rates...
  32. doi A respiratory function monitor improves mask ventilation
    F E Wood
    Division of Neonatal Services, Royal Women s Hospital, Carlton, Victoria, Australia
    Arch Dis Child Fetal Neonatal Ed 93:F380-1. 2008
    ..It showed the leak was more than halved, being reduced from 27% to 11% when 25 participants used the monitor to identify and correct the mask leak...
  33. doi Comparing the effectiveness of interventions to improve ventilation behavior in primary schools
    L M J Geelen
    Office of Environmental Health and Safety, Public Health Services Brabant Zeeland, Hertogenbosch, The Netherlands
    Indoor Air 18:416-24. 2008
    ..Indoor air quality can be improved by increasing ventilation. The objective of this study was to compare the effectiveness of different interventions to improve ventilation ..
  34. pmc Eye discomfort, headache and back pain among Mayan Guatemalan women taking part in a randomised stove intervention trial
    Esperanza Diaz
    Section for General Practice, Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien 31, N 5018 Bergen, Norway
    J Epidemiol Community Health 61:74-9. 2007
    ..Indoor air pollution (IAP) from combustion of biomass fuels represents a global health problem, estimated to cause 1.6 million premature deaths annually...
  35. doi Quantitative relationship of sick building syndrome symptoms with ventilation rates
    W J Fisk
    Indoor Environment Department, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Indoor Air 19:159-65. 2009
    ..and curves quantifying the change in sick building syndrome (SBS) symptom prevalence in office workers with ventilation rate...
  36. ncbi Testing selected behaviors to reduce indoor air pollution exposure in young children
    B R Barnes
    Medical Research Council of South Africa, PO Box 87373, Houghton, 2041 Johannesburg, South Africa
    Health Educ Res 19:543-50. 2004
    ..four indoor air pollution reduction behaviors (improve stove maintenance practices, child location practices, ventilation practices and reduce the duration of solid fuel burning)...
  37. ncbi Ocular, nasal, dermal and respiratory symptoms in relation to heating, ventilation, energy conservation, and reconstruction of older multi-family houses
    K Engvall
    Stockholm Office of Research and Statistics, Stockholm, Sweden
    Indoor Air 13:206-11. 2003
    ..aim was to study relationships between symptoms compatible with the sick building syndrome, type of heating and ventilation system, energy saving, and reconstruction in older dwellings...
  38. ncbi Noise exposure during noninvasive ventilation with a helmet, a nasal mask, and a facial mask
    Franco Cavaliere
    Institute of Anesthesia and Intensive Care, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168 Rome, Italy
    Intensive Care Med 30:1755-60. 2004
    To assess noise exposure during noninvasive ventilation (NIV) with different types of interface (helmet, nasal, and facial masks).
  39. doi Noninvasive ventilation in adult liver transplantation
    P Feltracco
    Department of Pharmacology, University Hospital of Padova, Padova, Italy
    Transplant Proc 40:1979-82. 2008
    Noninvasive ventilation (NIV) has proven to be a safe and effective technique in the treatment of respiratory failure complicating various medical and surgical diseases...
  40. ncbi Particulate matter and carbon dioxide in classrooms - the impact of cleaning and ventilation
    U Heudorf
    Public Health Service of the City of Frankfurt M, Braubachstr 18 22, D 60311 Frankfurt, Germany
    Int J Hyg Environ Health 212:45-55. 2009
    The objective of the study was to measure the indoor air quality in classrooms with special emphasis on particulate matter (PM 10) and carbon dioxide (CO(2)) and the impact of cleaning and ventilation.
  41. ncbi Gas cooking, kitchen ventilation, and asthma, allergic symptoms and sensitization in young children--the PIAMA study
    S M Willers
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Allergy 61:563-8. 2006
    ..Kitchen ventilation characteristics may modify the relationship between gas cooking and respiratory health...
  42. ncbi Will drivers for home energy efficiency harm occupant health?
    Angie Bone
    Health Protection Agency, 7th Floor, Holborn Gate, 330 High Holborn, London, WC1V 7PR, UK
    Perspect Public Health 130:233-8. 2010
    ..The main concerns for health surround the potential for poor indoor air quality if ventilation is insufficient and the possible risks of overheating in heatwave conditions...
  43. doi Use of personalized ventilation for improving health, comfort, and performance at high room temperature and humidity
    A K Melikov
    International Centre for Indoor Environment and Energy, Department of Civil Engineering, Technical University of Denmark, Kgs Lyngby, Denmark
    Indoor Air 23:250-63. 2013
    The effect of personalized ventilation (PV) on people's health, comfort, and performance in a warm and humid environment (26 and 28°C at 70% relative humidity) was studied and compared with their responses in a comfortable environment (..
  44. doi Secondhand smoke transfer and reductions by air sealing and ventilation in multiunit buildings: PFT and nicotine verification
    D L Bohac
    Center for Energy and Environment, Minneapolis, MN, USA
    Indoor Air 21:36-44. 2011
    ..and after treatments that sealed boundaries between units and provided a minimum amount of continuous exhaust ventilation of each unit. Six buildings in Minnesota were studied...
  45. ncbi [Nitrogen dioxide and ozone exposures in a population sample from Ile-de-France]
    M Saintot
    Groupe d Epidémiologie Métabolique INSERM CRLC, Centre de Recherches en Cancérologie, Parc Euromedecine, 34298 Montpellier Cedex 5
    Rev Epidemiol Sante Publique 48:2S54-61. 2000
    ..The present study was conducted to evaluated individual exposure to NO(2) and O(3) and to identify the environmental determinants of exposure in a larger population living in different environmental conditions...
  46. doi Perceived indoor air quality, air-related symptoms and ventilation in Finnish hospitals
    Ulla Maija Hellgren
    Finnish Institute of Occupational Health, Helsinki, Finland
    Int J Occup Med Environ Health 24:48-56. 2011
    Good ventilation is more important in hospitals than in many other buildings...
  47. doi The relationship between atopic dermatitis and indoor environmental factors: a cross-sectional study among Japanese elementary school children
    Shigekazu Ukawa
    Department of Public Health Science, Hokkaido University Graduate School of Medicine, Hokkaido, Sapporo, Japan
    Int Arch Occup Environ Health 86:777-87. 2013
    ..This study aimed to determine that home environmental factors were associated with atopic dermatitis in Japanese elementary school children...
  48. pmc Enhancing ventilation in homes of children with asthma: cost-effectiveness study alongside randomised controlled trial
    Rhiannon T Edwards
    Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK
    Br J Gen Pract 61:e733-41. 2011
    ..There has been little rigorous economic analysis of the relationship between asthma and improved housing...
  49. ncbi Nationwide study of sick house syndrome: comparison of indoor environment of newly built dwellings between Sapporo city and Southern areas including those in Honshu and Kyushu
    Ayako Kanazawa
    Department of Public Health Sciences, Hokkaido University Graduate School of Medicine
    Nihon Eiseigaku Zasshi 65:447-58. 2010
    ..The aims of this study are to evaluate the associations between residential factors and sick house syndrome (SHS) in a cold region and in a temperate region in Japan...
  50. doi Carbon dioxide (CO2) demand-controlled ventilation in university computer classrooms and possible effects on headache, fatigue and perceived indoor environment: an intervention study
    Dan Norback
    Department of Medical Science, Occupational and Environmental Medicine, University Hospital, Uppsala University, 751 85 Uppsala, Sweden
    Int Arch Occup Environ Health 86:199-209. 2013
    To study the effects of a CO(2) demand-controlled ventilation system (variable flow) in computer classrooms on perceived air quality and sick building syndrome.
  51. ncbi An evaluation of hospital special-ventilation-room pressures
    N Rice
    Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis 55455, USA
    Infect Control Hosp Epidemiol 22:19-23. 2001
    ..quantitate the magnitude and consistency of positive (airflow out) and negative (airflow in) hospital special-ventilation-room (SVR) airflow...
  52. ncbi Modeling ventilation and radon in new Dutch dwellings
    M P M Janssen
    National Institute of Public Health and the Environment RIVM LSO, 3720 BA Bilthoven, The Netherlands
    Indoor Air 13:118-27. 2003
    Indoor radon concentrations were estimated for various ventilation conditions, the differences being mainly related to the airtightness of the dwelling and the ventilation behavior of its occupants...
  53. doi Removal of exhaled particles by ventilation and deposition in a multibed airborne infection isolation room
    H Qian
    Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Indoor Air 20:284-97. 2010
    ..Previous studies showed that the downward ventilation recommended by Centers for Disease Control and Prevention (CDC) could not produce the expected 'laminar' flow ..
  54. ncbi Do we really need laminar flow ventilation in the operating room to prevent surgical site infections?
    Pamela A Lipsett
    Ann Surg 248:701-3. 2008
  55. ncbi Effectiveness of a custom-fitted flange and local exhaust ventilation (LEV) system in controlling the release of nanoscale metal oxide particulates during reactor cleanout operations
    Mark M Methner
    National Institute for Occupational Safety and Health, Centers for Disease Control, Atlanta, GA, USA
    Int J Occup Environ Health 16:475-87. 2010
    ..A field study was conducted to evaluate the effectiveness of a portable, HEPA-filtered, local exhaust ventilation system equipped with a custom-fitted flange for controlling the emission of engineered nanoscale metal oxide ..
  56. ncbi A pilot study on the effects of two ventilation methods on weld fume exposures in a shipyard confined space welding task
    Steven J Wurzelbacher
    Mitsui Sumitomo Loss Control, Cincinnati, Ohio, USA
    Appl Occup Environ Hyg 17:735-40. 2002
  57. pmc Sonic anemometry to measure natural ventilation in greenhouses
    Alejandro López
    Department of Rural Engineering, University of Almeria, Ctra Sacramento s n, 04120 Almeria, Spain
    Sensors (Basel) 11:9820-38. 2011
    The present work has developed a methodology for studying natural ventilation in Mediterranean greenhouses by means of sonic anemometry...
  58. ncbi Evaluation of microbial contamination of air in two haematology departments equipped with ventilation systems with different filtration devices
    P Crimi
    Department of Health Sciences, San Martino Hospital, University of Genoa, Italy
    J Prev Med Hyg 50:33-6. 2009
    ..In this study, we evaluated microbial contamination of the air in two divisions with high risk patients, focusing on the validity of the air system with correlation to the presence or not of the HEPA absolute filters...
  59. ncbi Manganese exposures during shielded metal arc welding (SMAW) in an enclosed space
    Michael K Harris
    Hamlin and Harris, Inc, Baton Rouge, Louisiana 70808, USA
    J Occup Environ Hyg 2:375-82. 2005
    The work reported here evaluates the effectiveness of various rates of dilution ventilation in controlling welder exposures to manganese in shielded metal arc welding (SMAW) fume when working in enclosed or restricted spaces...
  60. ncbi Worker performance and ventilation in a call center: analyses of work performance data for registered nurses
    C C Federspiel
    Center for the Built Environment, University of California, Berkeley, CA 94720, USA
    Indoor Air 14:41-50. 2004
    We investigated the relationship between ventilation rates and individual work performance in a call center, and controlled for other factors of the indoor environment...
  61. ncbi Estimating the resuspension rate and residence time of indoor particles
    Jing Qian
    Department of Civil and Environmental Engineering, Clarkson University, Potsdam, NY 13699, USA
    J Air Waste Manag Assoc 58:502-16. 2008
    ..However, resuspension substantially increases PM concentration, and thus increases short-term inhalation exposure to indoor PM pollutants...
  62. ncbi Effect of ultraviolet germicidal lights installed in office ventilation systems on workers' health and wellbeing: double-blind multiple crossover trial
    Dick Menzies
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Quebec, Canada
    Lancet 362:1785-91. 2003
    ..We assessed whether ultraviolet germicidal irradiation (UVGI) of drip pans and cooling coils within ventilation systems of office buildings would reduce microbial contamination, and thus occupants' work-related symptoms.
  63. doi Cooking fuel type, household ventilation, and the risk of acute lower respiratory illness in urban Bangladeshi children: a longitudinal study
    E L Murray
    Department of Epidemiology, Rollins School of Public Health of Emory University, Atlanta, GA, USA
    Indoor Air 22:132-9. 2012
    ..However, few studies have evaluated the influence of natural household ventilation indicators on ALRI...
  64. doi Can a photocatalytic air purifier be used to improve the perceived air quality indoors?
    J Kolarik
    International Centre for Indoor Environment and Energy, Department of Civil Engineering, Technical University of Denmark, Lyngby, Denmark
    Indoor Air 20:255-62. 2010
    ..PAQ in the rooms polluted by building materials (used carpet, old linoleum, and old chipboard), and a used ventilation filter as well as a mixture of building materials, used ventilation filter and cathode-ray tube computer ..
  65. doi Evaluation of biological air filters for livestock ventilation air by membrane inlet mass spectrometry
    Anders Feilberg
    Dep of Aricultural Engineering, Faculty of Agricultural Sciences, Aarhus University, 8830 Tjele, Denmark
    J Environ Qual 39:1085-96. 2010
    ..Based on the results and published odor threshold values, it is estimated that the low removal efficiency of ROS is the main limitation for achieving a higher odor reduction...
  66. doi Association between substandard classroom ventilation rates and students' academic achievement
    U Haverinen-Shaughnessy
    The University of Tulsa, Indoor Air Program, Tulsa, OK 74104 3189, USA
    Indoor Air 21:121-31. 2011
    This study focuses on the relationship between classroom ventilation rates and academic achievement. One hundred elementary schools of two school districts in the southwest United States were included in the study...
  67. ncbi Ventilation performance in the operating theatre against airborne infection: numerical study on an ultra-clean system
    T T Chow
    Division of Building Science and Technology, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, China
    J Hosp Infect 59:138-47. 2005
    ..The study of the ultra-clean ventilation system investigated the effectiveness of the laminar flow in: (i) preventing bioaerosols released by the ..
  68. doi Effect of particle spatial distribution on particle deposition in ventilation rooms
    Bin Zhao
    Dept of Building Science, School of Architecture, Tsinghua University, Beijing, China
    J Hazard Mater 170:449-56. 2009
    We used simulations and experimental tests to investigate indoor particle deposition during four commonly used ventilation modes, including ceiling supply, side-up supply, side-down supply and bottom supply...
  69. ncbi Gas cooking, kitchen ventilation, and exposure to combustion products
    S M Willers
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Indoor Air 16:65-73. 2006
    ..The system was based on questions about type of cooking appliance, type and use of ventilation provisions, and kitchen size...
  70. doi Low home ventilation rate in combination with moldy odor from the building structure increase the risk for allergic symptoms in children
    L Hagerhed-Engman
    Department of Building Physics and Indoor Environment, SP Technical Research Institute of Sweden, Boras, Sweden
    Indoor Air 19:184-92. 2009
    ..Furthermore, low ventilation rate in combination with moldy odor along the skirting board further increased the risk for three out of four ..
  71. ncbi Molds in floor dust and building-related symptoms in adolescent school children
    H W Meyer
    Epidemiological Research Unit, Clinic of Occupational and Environmental Medicine, H S Copenhagen University Hospital, Bispebjerg, Copenhagen NV, Denmark
    Indoor Air 14:65-72. 2004
    ..building characteristics including mold infestation were assessed, and dust was collected from floors, air, and ventilation ducts during a working day. Dust was examined for endotoxin level, and cultivated for viable molds...
  72. ncbi Ventilation system, indoor air quality, and health outcomes in Parisian modern office workers
    D Vincent
    Service de Medecine Interne, Hopital Louis Mourier, Colombes, France
    Environ Res 75:100-12. 1997
    A cross-sectional study was carried out to determine the effect on health of exposure to different types of ventilation, taking indoor environmental measurements (IEMs) of major contaminants and aeroallergens into account...
  73. ncbi Human response to personalized ventilation and mixing ventilation
    J Kaczmarczyk
    International Center for Indoor Environment and Energy, Technical University of Denmark, Kgs Lyngby, Denmark
    Indoor Air 14:17-29. 2004
    The response of 60 human subjects to a personalized ventilation system (PVS), providing control of positioning of the air terminal device and the airflow rate, was compared with the response to mixing ventilation (MV)...
  74. doi Exhaled air dispersion and removal is influenced by isolation room size and ventilation settings during oxygen delivery via nasal cannula
    David S Hui
    Stanley Ho Center for Emerging Infectious Diseases, Department Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    Respirology 16:1005-13. 2011
    ..We compared the exhaled air dispersion distances during oxygen delivery via nasal cannula to a human-patient simulator (HPS) in two different isolation rooms...
  75. doi Adaptive support ventilation for gynaecological laparoscopic surgery in Trendelenburg position: bringing ICU modes of mechanical ventilation to the operating room
    Julio Llorens
    Hospital Clinico Universitario de Valencia, Anaesthesiology and Critical Care, Valencia, Spain
    Eur J Anaesthesiol 26:135-9. 2009
    The aim of the present study was to test the efficacy of adaptive support ventilation (ASV) to automatically adapt the ventilatory settings to the changes in the respiratory mechanics that occur during pneumoperitoneum and Trendelenburg ..
  76. ncbi Summary of human responses to ventilation
    O A Seppänen
    Helsinki University of Technology, Finland
    Indoor Air 14:102-18. 2004
    It is known that ventilation is necessary to remove indoor-generated pollutants from indoor air or dilute their concentration to acceptable levels...
  77. doi Effects of thermal discomfort in an office on perceived air quality, SBS symptoms, physiological responses, and human performance
    L Lan
    Institute of Refrigeration and Cryogenics, Shanghai Jiao Tong University, China
    Indoor Air 21:376-90. 2011
    ..Task performance decreased when the subjects felt warm. Their heart rate, respiratory ventilation, and end-tidal partial pressure of carbon dioxide increased significantly, and their arterial oxygen saturation ..
  78. pmc Wind-driven roof turbines: a novel way to improve ventilation for TB infection control in health facilities
    Helen Cox
    Medecins Sans Frontieres, Cape Town, South Africa
    PLoS ONE 7:e29589. 2012
    ..Although improving ventilation may reduce transmission, there is a lack of evidence to support low-cost practical interventions...
  79. doi Short-term airing by natural ventilation - implication on IAQ and thermal comfort
    P Heiselberg
    Department of Civil Engineering, Aalborg University, DK 9000 Aalborg, Denmark
    Indoor Air 20:126-40. 2010
    The need to improve the energy efficiency of buildings requires new and more efficient ventilation systems...
  80. ncbi Perceptions of indoor air quality associated with ventilation system types in elementary schools
    M R Kinshella
    Tri-County Health Department, Englewood, Colorado, USA
    Appl Occup Environ Hyg 16:952-60. 2001
    ..The purpose of this study was to evaluate possible associations between ventilation system type and occupant perception of indoor air quality...
  81. ncbi Indoor climate in interior Alaska: simultaneous measurement of ventilation, benzene and toluene in residential indoor air of two homes
    Maggie A Isbell
    Department of Chemistry and Biochemistry, University of Alaska Fairbanks, Fairbanks, AK 99775 6160, USA
    Sci Total Environ 345:31-40. 2005
    ..These calculations demonstrated that the home with the air-to-air heat exchangers and forced ventilation had less transport of aromatics than the unventilated home...
  82. ncbi Analysis of risk factors for sternal surgical site infection: emphasizing the appropriate ventilation of the operating theaters
    Serap Simsek Yavuz
    Department of Infectious Disease and Clinical Microbiology, Siyami Ersek Thoracic and Cardiovascular Surgery Hospital, Uskudar, Turkey
    Infect Control Hosp Epidemiol 27:958-63. 2006
    ..To determine the incidence of and identify risk factors for sternal surgical site infection (SSI)...
  83. doi Validation of the criteria for initiating the cleaning of heating, ventilation, and air-conditioning (HVAC) ductwork under real conditions
    Jacques Lavoie
    Institut de recherche Robert Sauve en sante et en securite du travail IRSST, Montreal, Quebec, Canada
    J Occup Environ Hyg 8:467-72. 2011
    Dust accumulation in the components of heating, ventilation, and air-conditioning (HVAC) systems is a potential source of contaminants...
  84. ncbi Dispersion of exhaled droplet nuclei in a two-bed hospital ward with three different ventilation systems
    H Qian
    Department of Mechanical Engineering, The University of Hong Kong, Hong Kong SAR, China
    Indoor Air 16:111-28. 2006
    Effective ventilation in general hospital wards is important for controlling the airborne transmission of infectious respiratory diseases...
  85. ncbi Ventilation performance in operating theatres against airborne infection: review of research activities and practical guidance
    T T Chow
    Division of Building Science and Technology, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, People s Republic of China
    J Hosp Infect 56:85-92. 2004
    ..site infection risk due to airborne bacteria is a key area of consideration in developing operating theatre ventilation design and monitoring procedures...
  86. pmc Natural ventilation for the prevention of airborne contagion
    A Roderick Escombe
    Department of Infectious Diseases and Immunity, Imperial College London, London, United Kingdom
    PLoS Med 4:e68. 2007
    ..Natural ventilation may offer a low-cost alternative...
  87. ncbi Hospital ventilation and risk for tuberculous infection in canadian health care workers. Canadian Collaborative Group in Nosocomial Transmission of TB
    D Menzies
    Montreal Chest Institute, 3650 St Urbain Street, Montreal, Quebec H2X 2P4, Canada
    Ann Intern Med 133:779-89. 2000
    ..The risk for and determinants of transmission of tuberculosis in hospitals caring for moderate numbers of patients with tuberculosis remain uncertain...
  88. ncbi Source strengths of ultrafine and fine particles due to cooking with a gas stove
    Lance A Wallace
    U S Environmental Protection Agency, 11568 Woodhollow Court, Reston, Virginia 20191, USA
    Environ Sci Technol 38:2304-11. 2004
    ..strengths calculated here are independent of these variables and may be used to estimate number and volume concentrations in other types of homes with widely varying volumes, ventilation rates, and heating and air-conditioning practices.
  89. ncbi Impact of indoor air temperature and humidity in an office on perceived air quality, SBS symptoms and performance
    L Fang
    International Centre for Indoor Environment and Energy, Technical University of Denmark
    Indoor Air 14:74-81. 2004
    ..work were studied in a real office space at three levels of air temperature and humidity and two levels of ventilation rate (20 degrees C/40%, 23 degrees C/50%, 26 degrees C/60% RH at 10 l s(-1) p(-1) outside air, and 20 degrees C/..
  90. ncbi Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises
    J W Tang
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Hosp Infect 64:100-14. 2006
    ..On this basis, recommendations are made to improve the control of aerosol-transmitted infections in hospitals as well as in the design and construction of future isolation facilities...
  91. ncbi Impact of improved stoves, house construction and child location on levels of indoor air pollution exposure in young Guatemalan children
    Nigel Bruce
    Department of Public Health, University of Liverpool, UK
    J Expo Anal Environ Epidemiol 14:S26-33. 2004
    The goal of this study was to assess the impact of improved stoves, house ventilation, and child location on levels of indoor air pollution and child exposure in a rural Guatemalan population reliant on wood fuel...
  92. ncbi Evidence of airborne transmission of the severe acute respiratory syndrome virus
    Ignatius T S Yu
    Department of Community and Family Medicine, Chinese University of Hong Kong, Hong Kong, China
    N Engl J Med 350:1731-9. 2004
    ....
  93. doi The ventilation of multiple-bed hospital wards: review and analysis
    Clive B Beggs
    Bradford Infection Group, School of Engineering, Design and Technology, University of Bradford, Bradford, UK
    Am J Infect Control 36:250-9. 2008
    ..This is because relatively little research work has been done in the ventilation of these areas compared with that done in operating theatres and isolation rooms...
  94. doi Operating room ventilation with laminar airflow shows no protective effect on the surgical site infection rate in orthopedic and abdominal surgery
    Christian Brandt
    Charité Universtitätsmedizin Berlin, Berlin, Germany
    Ann Surg 248:695-700. 2008
    To evaluate whether operating room (OR) ventilation with (vertical) laminar airflow impacts on surgical site infection (SSI) rates.
  95. ncbi Gas-phase organics in environmental tobacco smoke. 1. Effects of smoking rate, ventilation, and furnishing level on emission factors
    Brett C Singer
    E O Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Environ Sci Technol 36:846-53. 2002
    ..over a 24-h period, were calculated by mass balance from measured compound concentrations and chamber ventilation rates in a 50-m3 room constructed and furnished with typical materials...
  96. ncbi Wind-induced ventilation of the giant nests of the leaf-cutting ant Atta vollenweideri
    C Kleineidam
    Biozentrum, University of Wurzburg, Am Hubland, 97074 Wurzburg, Germany
    Naturwissenschaften 88:301-5. 2001
    ..of elaborate nest architecture for the control of nest climate, we investigated the mechanisms governing nest ventilation in a large field nest of Atta vollenweideri...
  97. ncbi Contribution of incense burning to indoor PM10 and particle-bound polycyclic aromatic hydrocarbons under two ventilation conditions
    S C C Lung
    Department of Public Health, Chung Shan Medical University, Taichung, Taiwan
    Indoor Air 13:194-9. 2003
    ..On average, PM10 and associated PAH concentrations were about 371 and 0.23 microg/m3 lower, respectively, in ventilated environments compared with closed conditions. Concentrations were elevated for at least 6 h under closed conditions...
  98. pmc Air trapping on chest CT is associated with worse ventilation distribution in infants with cystic fibrosis diagnosed following newborn screening
    Graham L Hall
    Respiratory Medicine, Princess Margaret Hospital for Children, Perth, Australia
    PLoS ONE 6:e23932. 2011
    ..children with cystic fibrosis (CF) structural lung damage assessed using chest CT is associated with abnormal ventilation distribution...
  99. ncbi Daily time spent indoors in German homes--baseline data for the assessment of indoor exposure of German occupants
    Sabine Brasche
    Friedrich Schiller University Jena, Institute of Occupational, Social and Environmental Medicine, Department of Indoor Climatology, Bachstrasse 18, 07740 Jena, Germany
    Int J Hyg Environ Health 208:247-53. 2005
    ..location, city size, region, building type, owner-occupier status, number of people at home, smoking and ventilation habits, moisture emission and ill health factors such as asthma, allergy and number of acute respiratory ..
  100. doi Effect of flow-triggered adaptive servo-ventilation compared with continuous positive airway pressure in patients with chronic heart failure with coexisting obstructive sleep apnea and Cheyne-Stokes respiration
    Takatoshi Kasai
    Sleep Center, Toranomon Hospital, Tokyo, Japan
    Circ Heart Fail 3:140-8. 2010
    ..Recently, it was reported that adaptive servo-ventilation (ASV) can effectively treat sleep-disordered breathing...
  101. ncbi Mobile zoned/exponential LAF screen: a new concept in ultra-clean air technology for additional operating room ventilation
    B Friberg
    Department of Nursing, Umea University, S 901 87 Umea, Sweden
    J Hosp Infect 50:286-92. 2002
    ..4 m/s) was investigated as an addition to conventional turbulent/mixing operating room ventilation. The evaluation was performed during strictly standardized sham operations reflecting conditions during major ..

Research Grants79

  1. INTERVENTIONS TO PROMOTE VENTILATOR WEANING
    Kathleen Stone; Fiscal Year: 2002
    DESCRIPTION (As Adapted from the Investigator's Abstract): Weaning the critically ill patient from mechanical ventilation (MV) to spontaneous ventilation (SpV) continues to be a significant challenge for nursing...
  2. PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX II
    CHARLES HALES; Fiscal Year: 2003
    ..Pulmonary embolism is common, yet frequently undiagnosed and fatal. Ventilation/perfusion lung scans are the most commonly used test...
  3. A Hybrid PARP Inhibitor and Redox Catalyst for Lung Transplantation
    GARRY JOHN SOUTHAN; Fiscal Year: 2012
    ..to translate into clinical endpoints in LIRI of decreased: 1) pulmonary shunt, 2) duration of mechanical ventilation, 3) length of hospitalization, and 4) all-cause 30 and 365 day mortality...
  4. The influence of air pollution mixtures on biomarkers of airway oxidative stress
    Roby Greenwald; Fiscal Year: 2013
    ..Since the elevated ventilation rate associated with physical activity leads to increased inhalation of ambient oxidants, the investigatorswill ..
  5. Comparison of Diesel and Biodiesel Emissions and Health Effects in Underground Mi
    Jefferey L Burgess; Fiscal Year: 2013
    ..Background: Despite mine ventilation and emission controls, underground miners are exposed to concentrations of diesel exhaust that frequently ..
  6. Monitoring cellular redox signaling and oxidant stress in vivo
    Paul T Schumacker; Fiscal Year: 2010
    ..system to demonstrate efficacy, we will measure redox changes in smooth muscle cells in the intact lung during ventilation with different concentrations of oxygen...
  7. Lactoferrin Enhances Growth and Reduces Nosocomial Infection in Preterm Infants
    Karel Petrak; Fiscal Year: 2009
    ..Additionally, Secondary Efficacy Parameters shall evaluate the number of days on mechanical ventilation and/or nasal positive airway pressure, number of days on supplemental oxygen, and overall morbidity and ..
  8. Intrathoracic Pressure Regulator for Resuscitation
    Keith G Lurie; Fiscal Year: 2011
    ..intrathoracic pressure during the expiratory phase to subatmospheric levels after each positive pressure ventilation. The decrease in intrathoracic pressure, typically to -7 to -9 mmHg, creates a vacuum within the thorax ..
  9. Respiratory and autonomic plasticity following intermittent hypoxia
    JASON HAROLD MATEIKA; Fiscal Year: 2012
    ..that has been shown to manifest itself in animals following exposure to IH is long-term facilitation (LTF) of ventilation and sympathetic nervous system activity (SNSA)...
  10. Novel Means to Establish Free Radical Balance in the Neonatal Premature Lung
    Prakash Jagtap; Fiscal Year: 2011
    ..Current standard of care is limited to low volume mechanical ventilation and the exogenous endotracheal administration of surfactant...
  11. Pharmacologic Interventions for Cardiovascular Disease in Obstructive Sleep Apnea
    Barbara J Morgan; Fiscal Year: 2013
    ..Excess superoxide in the carotid body, in turn, augments chemoreflex control of sympathetic outflow and ventilation. At the same time, activation of RAS and XO in resistance arteries leads to impairment in endothelium- ..
  12. Mechanisms of innate immune response modulation by mechanical ventilation
    William A Altemeier; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Mechanical ventilation is frequently used to support critically ill patients even in the absence of overt lung injury...
  13. PARP Inhibitor and Redox Catalyst for Ventilatory Trauma
    Prakash Jagtap; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): High volume mechanical ventilation (MV) induces a lethal pulmonary complication, termed "ventilator induced lung injury" (VILI), via the generation of toxic free radical and oxidant species that ..
  14. Antenatal Betamethasone in Late Preterm Gestation Lambs
    SATYANARAYANA LAKSHMINRUSIMHA; Fiscal Year: 2010
    ..production and release) or instrumented for evaluation of pulmonary vascular resistance, oxygenation and ventilation for 6 h...
  15. Targeting thermoreceptors for therapeutic hypothermia
    Sean P Marrelli; Fiscal Year: 2012
    ..currently used to prevent the shiver response produce respiratory depression and typically require patient ventilation. The combination of difficult implementation, slow achievement of target temperature, and clinical ..
  16. Role of Dendritic Ca2+ Transients in Respiratory Rhythm Generation
    Jack L Feldman; Fiscal Year: 2010
    ..such as sleep apnea, apnea of prematurity, congenital central hypoventilation syndrome, central alveolar hypo- ventilation syndrome, hyperventilation syndrome, Rett syndrome, and perhaps sudden infant death syndrome, leads to serious ..
  17. Clinical and genomic responses to remote ischemic preconditioning
    Brian W McCrindle; Fiscal Year: 2010
    ..will reflect multi-organ dysfunction and inflammation and their impact, and include duration of mechanical ventilation, duration of stay in the intensive care unit, and physiologic measures over the first 48 hours after surgery...
  18. Inhibitors of isoprenoid synthesis for antibacterial therapy
    Donald T Moir; Fiscal Year: 2013
    ..g., HIV and cancer), cystic fibrosis patients, and those on mechanical ventilation or with burn wounds...
  19. EEG Synchrony, perinatal risk and outcome: analysis of CHIME data
    PHILIP GEORGE GRIEVE; Fiscal Year: 2010
    ..3) postnatal factors such as intraventricular hemorrhage, nosocomial infections and sepsis, days on mechanical ventilation, necrotizing enterocolitis and chronic lung disease...
  20. Effect of Neonatal Hyperoxia on Alveolar Development and Infection
    MICHAEL A O'REILLY; Fiscal Year: 2012
    ABSTRACT Despite the use of exogenous surfactant, steroids, and mild ventilation, premature infants often require oxygen assistance and many develop bronchopulmonary dysplasia (BPD)...
  21. Foxf1 Transcription Factor in Development of Pulmonary Capillaries
    Vladimir V Kalinichenko; Fiscal Year: 2013
    ..Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in preterm infants following mechanical ventilation and high levels of supplemental oxygen...
  22. Right Heart-Pulmonary Vascular Interactions in Bronchopulmonary Dysplasia
    Marlowe Eldridge; Fiscal Year: 2013
    ..develop BPD, a chronic lung disease that affects VLBW infants (<1500 grams) who need long-term mechanical ventilation and oxygen therapy...
  23. Mechanisms of adaptive immunity to P. aeruginosa in the lung
    Gregory P Priebe; Fiscal Year: 2013
    ..infections in the form of either acute pneumonia in hospitalized patients (usually associated with mechanical ventilation) or chronic pneumonia in people with cystic fibrosis (CF)...
  24. Pathogenic Mechanisms of PBEF in Ventilator Induced Lung Injury
    Joe G N Garcia; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Mechanical ventilation is a life-saving intervention in critically ill patients with respiratory failure, but also directly contributes to lung injury and augments established acute lung injury (ALI),..
  25. Genetic Basis for Impaired Angiogenic Signaling in BPD
    STEVEN HERBERT ABMAN; Fiscal Year: 2012
    ..provided by applicant): Bronchopulmonary dysplasia (BPD) is the chronic lung disease that follows mechanical ventilation and oxygen therapy for respiratory failure in premature newborns...
  26. Antenatal betamethasone for persistent pulmonary hypertension of newborn
    Girija G Konduri; Fiscal Year: 2010
    ..After the ventilation studies are completed, lungs will be harvested from euthanized lambs for additional studies...
  27. Oxygen versus PAP for treatment of sleep apnea in chronic heart failure
    Henry Klar Yaggi; Fiscal Year: 2013
    ..following treatment of CSA with continuous positive airway pressure (CPAP) or adaptive pressure-support servo-ventilation (ASV), although the single long-term outcome study of CPAP therapy for CSA in HF found no difference in ..
  28. Acquisition of a MALDI-TOF/TOF MS for Glycomic and Lipidomic Research
    Larry S Schlesinger; Fiscal Year: 2010
    ..in the tear film in various states of eye disease, and hyperoxic lung injury following high frequency/pressure ventilation in premature infants...
  29. Mechanisms and consequences of sleep disordered breathing in COPD
    Cynthia D Brown; Fiscal Year: 2012
    ..are: 1) to better understand how normal changes in inspiratory resistance during sleep affect sleep quality and ventilation;2) to ascertain whether sleep fragmentation and nocturnal hypoxemia lead to changes in sympathetic activation ..
  30. Structure and function of stress fibers and cell adhesion sites
    Mary C Beckerle; Fiscal Year: 2013
    ..mice harboring mutations that affect components of the repair machinery for their response to mechanical ventilation, a clinically important intervention that often leads to pathophysiological consequences such as loss of ..
  31. Novel non-invasive device for treatment of elevated intracranial pressures
    Keith G Lurie; Fiscal Year: 2011
    ..during the expiratory phase to subatmospheric levels and providing a means to provide positive pressure ventilation. The decrease in intrathoracic pressure, typically to -7 to -9 mmHg, creates a vacuum within the thorax ..
  32. Immediate and Delayed Effects of Morphine on Brain Circuits: Animal and Human Cor
    Dusica Bajic; Fiscal Year: 2013
    ..receive prolonged opioids for sedation to reduce anxiety, agitation, stress responses, and to facilitate ventilation. Such treatment is associated with a high incidence of opioid tolerance and dependence, as well as long-term ..
  33. Developmental defects in serotonin neurons and the response to O2 and CO2
    George B Richerson; Fiscal Year: 2011
    ..We will expose adult and neonatal mice to hypercapnia and hypoxia, and measure ventilation, heart rate, motor activity and EEG...
  34. Bifunctional Redox Agent for the Treatment of PPHN
    GARRY JOHN SOUTHAN; Fiscal Year: 2011
    ..Current therapy includes mechanical ventilation, oxygen, and inhalational nitric oxide (iNO), a gas that selectively dilates the pulmonary vasculature but is ..
  35. Phase III Study Comparing Albumin and Hetastarch Therapy in Acute Lung Injury
    Gregory S Martin; Fiscal Year: 2013
    ..Caring for patients with ALI requires prolonged mechanical ventilation and supportive intensive care, resulting in reduced quality of life and contributing substantially to ..
  36. Single RNA sensitive probes for studying viral replication and budding
    Philip J Santangelo; Fiscal Year: 2013
    ..hRSV), an RNA virus, is the leading cause of viral pneumonia, bronchiolitis, respiratory failure, mechanical ventilation, and viral death in infants in the USA and worldwide, and causes nine times as many infant deaths as influenza ..
  37. Resuscitation using novel impedance threshold devices in pediatrics
    Keith G Lurie; Fiscal Year: 2013
    ..Rapid, large volume crystalloid infusion and positive intrathoracic pressure ventilation resuscitation strategies often increase morbidity and mortality following hemorrhage...
  38. RESPIRATORY PATTERN GENERATION STUDIED IN VITRO
    Jack L Feldman; Fiscal Year: 2012
    ..AIM B: Active expiration is essential at higher levels of ventilation, such as during exercise...
  39. CRCNS: Computation-Enabled Adaptive Ventilatory Control System
    Ranu Jung; Fiscal Year: 2013
    ..Most people with SCI that require ventilation management are initially supported with positive pressure-mechanical ventilation, which is associated with ..
  40. Trial of Late SURFactant (TOLSURF) to Prevent BPD - Clinical Coord Ctr
    ROBERTA ANDERSON BALLARD; Fiscal Year: 2013
    ..genetic component, and involves lung injury and inflammation secondary to treatment with oxygen and mechanical ventilation in an underdeveloped, immature lung...
  41. Trial Of Late SURFactant (TOLSURF) to Prevent BPD-Data Coordinating Center
    Dennis M Black; Fiscal Year: 2013
    ..genetic component, and involves lung injury and inflammation secondary to treatment with oxygen and mechanical ventilation in an underdeveloped, immature lung...
  42. Factors Associated with Ventilator-Associated Pneumonia Guideline Adherence
    Hiroko Kiyoshi-Teo; Fiscal Year: 2011
    ..hygiene, oral hygiene, semi-recumbent patient positioning, subglottic suctioning, early weaning from mechanical ventilation, and maintenance of a ventilator circuit...
  43. Cell Survival and Death in Oxidant Lung Injury
    MICHAEL A O'REILLY; Fiscal Year: 2013
    ..Although the therapeutic use of exogenous surfactant and milder ventilation strategies has reduced mortality, children and adolescents born prematurely have reduced lung function, ..
  44. 1st Tier Drugs+Theophylline in Pediatric Severe Asthma
    JERRY JOHN ZIMMERMAN; Fiscal Year: 2010
    ..is beneficial to most children with status asthmaticus, some require adjunctive therapy including mechanical ventilation. Previously, theophylline and various congeners were utilized as front-line therapy for asthma, both ..
  45. Coagulation and Fibrinolysis in Pediatric Insulin Titration Trial
    Anil Sapru; Fiscal Year: 2013
    ..Approximately 25% of critically ill children with heart and lung failure (i.e., those receiving mechanical ventilation ad/or inotropes) develop hyperglycemia within 24 hours of admission, and if the hyperglycemia is sustained (..
  46. The Role of Xanthine Oxidoreductase in Ventilator-Associated Lung Injury
    Paul M Hassoun; Fiscal Year: 2013
    ..of this application renewal, we now demonstrate that mechanical stress, in the context of high tidal volume ventilation, leads to profound re-arrangement of the pulmonary endothelial cytoskeleton, apoptosis, and capillary leakage, ..
  47. Testing the feasibility of patient-controlled sedation in ventilated ICU patients
    Craig R Weinert; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Mechanical ventilation (MV) is the most frequently used life-support modality in intensive care units (ICUs)...
  48. Genetic and Functional Profiles of Serotonergic Neuron Subtypes
    Rachael D Brust; Fiscal Year: 2013
    ..by us demonstrating that brain 5-HT neurons are capable of regulating the respiratory network, and thus lung ventilation, in response to elevated blood carbon dioxide (CO2) levels, and that at least a subset are also likely to act ..
  49. Sleep Disordered Breathing and Passive Limb Movement in Children with Paraplegia
    Marlyn Woo; Fiscal Year: 2013
    ..Passive limb movement, the rhythmic movement of extremities without voluntary effort, increases ventilation during sleep in subjects with intact spinal cords;the impact of this intervention in complete thoracic SCI (..
  50. Redox Regulation of Vascular cGMP Signaling in Neonatal Lungs
    Kathryn N Farrow; Fiscal Year: 2013
    ..mainstays of BPD therapy is oxygen (O2), but supraphysiologic O2 concentrations in combination with mechanical ventilation increase reactive oxygen species (ROS) production, inducing significant vascular dysfunction in neonates...
  51. The MIND USA Study
    E Wesley Ely; Fiscal Year: 2012
    ..investigation in 876 critically ill, delirious medical/surgical ICU patients who are (a) on mechanical ventilation or non-invasive positive pressure ventilation or (b) in shock on vasopressors...
  52. XeBox-E10 Gas Polarizer for Functional MRI of Pediatric Lung Disease
    SEAN BEDILION FAIN; Fiscal Year: 2013
    ..Recent advances in pulmonary MRI have enabled functional imaging of ventilation in childhood asthma using novel fast MRI methods during single bolus delivery of hyperpolarized 3He gas, an ..
  53. Imaging regional physiologic parameters of lung function
    Rahim R Rizi; Fiscal Year: 2011
    ..we designed and implemented various methods to accurately measure regional alveolar partial pressure of oxygen, ventilation, perfusion, and ventilation-to-perfusion ratio, as well as oxygen depletion rate and diffusivity of helium-3 in ..
  54. Aminoglycoside potentiators for P. aeruginosa therapy
    Donald T Moir; Fiscal Year: 2013
    ..g., HIV and cancer), cystic fibrosis (CF), on mechanical ventilation or with burn wounds. While P...
  55. Mechanisms of diaphragm muscle dysfunction in critical-illness myopathy
    CATHERINE S SASSOON; Fiscal Year: 2012
    ..Care Unit, referred to "critical-illness myopathy," occurs commonly in patients receiving prolonged mechanical ventilation combined with both neuromuscular junction blocking agents (NMBA) and corticosteroid (methylprednisolone, MP)...
  56. A novel treatment, TAT-HSP70, in attenuating lung injury in sepsis induced ARDS
    MARY MELANIE LYONS; Fiscal Year: 2012
    ..This is best treated with mechanical ventilation. However, use of exogenous respiratory support compounds immobility, muscular deconditioning, and critical ..
  57. Perioperative Use and Outcomes of Noninvasive Ventilation in Sleep Apnea
    Peter K Lindenauer; Fiscal Year: 2013
    ..of OSA in the ambulatory setting consists of continuous positive airway pressure, a form of noninvasive ventilation (NIV)...
  58. Excitability of afferents evoking the exercise pressor reflex
    Victor Ruiz-Velasco; Fiscal Year: 2013
    ..flow and oxygen to exercising muscles, include reflex increases in arterial blood pressure, cardiac output and ventilation. With respect to thin fiber muscle afferents, we propose to combine the power of the in vitro whole-cell patch- ..
  59. Assessment of lung function in neonates and infants
    IULIAN CONSTANTIN RUSET; Fiscal Year: 2013
    ..b>Ventilation imaging depicts regional patency of the airway tree, even down to the smallest airways...
  60. Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe Sepsis
    Pratik Pandharipande; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The need for mechanical ventilation (MV) secondary to sepsis is the leading cause of admission to the intensive care unit, often necessitating sedation for patient safety and comfort...
  61. Prediction of Physiological Events in People with Sleep Disordered Breathing
    Jonathan A Waxman; Fiscal Year: 2011
    ..breathing (SDB) refers to a spectrum of disorders characterized by abnormal respiratory patterns or levels of ventilation during sleep. The most common is obstructive sleep apnea (OSA)...
  62. Furlow Palatoplasty with Tensor Tenopexy for Otitis Media
    Joseph E Losee; Fiscal Year: 2013
    ..surgical procedures will include cleft lip repair (if present) at 3-6 months of age, bilateral placement of a ventilation tube (VT) at 3-6 months of age, the designated palatoplasty at approximately 9-11 months of age and repeat ..
  63. Neonatal Oxygen and Susceptibility to Respiratory Viral Infections
    MICHAEL A O'REILLY; Fiscal Year: 2013
    ..dysplasia (BPD) is a chronic lung disease seen in premature infants requiring oxygen supplementation and ventilation. Although the use of exogenous surfactant and mild ventilation strategies has reduced mortality, infants who ..
  64. Effect of Prenatal Nicotinic Exposure on Control of Hypoxic Ventilatory Response
    Fadi Xu; Fiscal Year: 2013
    ..It is generally accepted that activation of PCFs inhibits ventilation via releasing glutamate that stimulates PCF-driven neurons in the caudal and middle nucleus tractus solitarius (..
  65. Temperature & Vasomotor Tone During the First 5 Days in Preterms Less than 1000g
    ROBIN BRITT KNOBEL; Fiscal Year: 2010
    ..Events causing decreased internal body temperatures may include suctioning, ventilation with an oxygen bag or infusion of fluids into umbilical catheters...
  66. NEUROTRANSMITTERS AND VENTILATORY CONTROL
    EARL OLSON; Fiscal Year: 1990
    ..long range goal of this research is to determine the basic neurochemical mechanisms linking chemical drive and ventilation. Unanesthetized, unrestrained rats prepared with chronically indwelling femoral artery catheters will be used ..
  67. SURGICAL STUDIES OF SEVERE RESPIRATORY FAILURE
    Joseph Zwischenberger; Fiscal Year: 2004
    ..Unfortunately, mechanical ventilation targeted to restore normal blood gases causes high peak airway pressure with iatrogenic barotrauma or ..
  68. AIR CONDITIONING BY THE TRACHEA--STIMULI AND MECHANISMS
    Mark Deffebach; Fiscal Year: 1993
    ..As ventilation increases, the trachea becomes a major source of the heat and water required for the conditioning of inspired ..
  69. PERINATAL PULMONARY CIRCULATION--VASOACTIVE MEDIATORS
    Michael Heymann; Fiscal Year: 1999
    With the onset of ventilation at birth, pulmonary blood flow (PBF) increases 8- 10-fold with a concomitant fall in pulmonary vascular resistance...
  70. SoundTrak: A Data Acquisition and Analysis System for OSDB
    B Parker; Fiscal Year: 2009
    ..g., a sibling sleeping in the same room, noise from heating, ventilation, and air conditioning systems, etc)...
  71. VENTILATION CONTROL TO REDUCE AIRBORNE CONTAMINANTS
    PATRICK O SHAUGHNESSY; Fiscal Year: 2001
    ..b>Ventilation systems associated with swine confinements are largely designed to provide a comfortable climate for the pigs...
  72. LUNG VASCULAR EFFECTS OF HIGH FREQUENCY VENTILATION
    MUKUL BANERJEE; Fiscal Year: 1992
    The objective of this project is to investigate the effects of high frequency ventilation (HFV) on pulmonary vascular function...
  73. Entrainment-based mechanical ventilation
    Chi Sang Poon; Fiscal Year: 2010
    ..Mechanical ventilation is a life support procedure that is indicated for a wide variety of acute or chronic respiratory failure ..
  74. MECHANICAL VENTILATION AND RESPIRATORY MUSCLES
    Scott Powers; Fiscal Year: 2004
    DESCRIPTION (Applicant's abstract): Mechanical ventilation (MV) is used clinically to sustain ventilation in patients who are incapable of independently maintaining adequate alveolar ventilation...
  75. LIQUID VENTILATION IN ARDS
    Ronald Hirschl; Fiscal Year: 2000
    ..Gas exchange may be successfully carried out during partial liquid ventilation (PLV, gas ventilation of the perfluorocarbon- filled lungs)...
  76. CTRIP Ex-vivo perfusion and ventilation of lungs to assess transplant suitability
    Thomas M Egan; Fiscal Year: 2010
    ..The aims of this proposal are: 1). to perfect a technique of lung perfusion and ventilation outside the body (ex-vivo) to reliably assess lung function and suitability for transplant;2)...
  77. Center of Predictive Medicine for Biodefense
    MANUAL MARTINEZ; Fiscal Year: 2007
    ..The facility building will include a penthouse that will be limited to facility mechanical and heating, ventilation, and air-conditioning (HVAC) components...
  78. Formaldehyde and Other Pollutants from Ozone Reactions on Ventilation Systems
    Hugo Destaillats; Fiscal Year: 2010
    ..project is aimed at studying ozone reactions with particulate matter and sorbed chemicals collected on heating, ventilation and air conditioning (HVAC) filters. The study will also test the inertness of filter media...
  79. Ventilation Improves Lung Physiology and Biology
    Bela Suki; Fiscal Year: 2006
    It is believed that during mechanical ventilation (MV), over-distension of lung units and/or shear forces generated during repetitive opening and closing of collapsed airways and atelectatic alveolar regions can exacerbate and may even ..