environment

Summary

Summary: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.

Top Publications

  1. ncbi Ecological responses to recent climate change
    Gian Reto Walther
    Institute of Geobotany, University of Hannover, Nienburger Str 17, 30167 Hannover, Germany
    Nature 416:389-95. 2002
  2. pmc The reorienting system of the human brain: from environment to theory of mind
    Maurizio Corbetta
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 58:306-24. 2008
  3. ncbi Climate change, human impacts, and the resilience of coral reefs
    T P Hughes
    Centre for Coral Reef Biodiversity, James Cook University, Townsville, Qld 4811, Australia
    Science 301:929-33. 2003
  4. ncbi Hepatocellular carcinoma pathogenesis: from genes to environment
    Paraskevi A Farazi
    Department of Genetics, Division of Medical Sciences, Harvard University, Boston, Massachusetts 02115, USA
    Nat Rev Cancer 6:674-87. 2006
  5. ncbi Biodiversity and ecosystem functioning: current knowledge and future challenges
    M Loreau
    Laboratoire d Ecologie, UMR 7625, Ecole Normale Superieure, 46 rue d Ulm, F 75230 Paris cedex 05, France
    Science 294:804-8. 2001
  6. ncbi Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions
    Lance W Hahn
    Program in Human Genetics and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical School, Nashville, TN 37232 0700, USA
    Bioinformatics 19:376-82. 2003
  7. ncbi Epigenetics and the environment: emerging patterns and implications
    Robert Feil
    Institute of Molecular Genetics IGMM, CNRS UMR 5535 and University of Montpellier, 1919 Route de Mende, 34293 Montpellier, France cnrs fr
    Nat Rev Genet 13:97-109. 2011
  8. pmc Genomic expression programs in the response of yeast cells to environmental changes
    A P Gasch
    Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305 5428, USA
    Mol Biol Cell 11:4241-57. 2000
  9. ncbi Phenotypic diversity, population growth, and information in fluctuating environments
    Edo Kussell
    Laboratory of Living Matter and Center for Studies in Physics and Biology, Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021 6399, USA
    Science 309:2075-8. 2005
  10. ncbi Understanding physical activity environmental correlates: increased specificity for ecological models
    Billie Giles-Corti
    School of Population Health, The University of Western Australia, Perth, Australia
    Exerc Sport Sci Rev 33:175-81. 2005

Detail Information

Publications333 found, 100 shown here

  1. ncbi Ecological responses to recent climate change
    Gian Reto Walther
    Institute of Geobotany, University of Hannover, Nienburger Str 17, 30167 Hannover, Germany
    Nature 416:389-95. 2002
    ..Although we are only at an early stage in the projected trends of global warming, ecological responses to recent climate change are already clearly visible...
  2. pmc The reorienting system of the human brain: from environment to theory of mind
    Maurizio Corbetta
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 58:306-24. 2008
    ....
  3. ncbi Climate change, human impacts, and the resilience of coral reefs
    T P Hughes
    Centre for Coral Reef Biodiversity, James Cook University, Townsville, Qld 4811, Australia
    Science 301:929-33. 2003
    ..International integration of management strategies that support reef resilience need to be vigorously implemented, and complemented by strong policy decisions to reduce the rate of global warming...
  4. ncbi Hepatocellular carcinoma pathogenesis: from genes to environment
    Paraskevi A Farazi
    Department of Genetics, Division of Medical Sciences, Harvard University, Boston, Massachusetts 02115, USA
    Nat Rev Cancer 6:674-87. 2006
    ....
  5. ncbi Biodiversity and ecosystem functioning: current knowledge and future challenges
    M Loreau
    Laboratoire d Ecologie, UMR 7625, Ecole Normale Superieure, 46 rue d Ulm, F 75230 Paris cedex 05, France
    Science 294:804-8. 2001
    ..A major future challenge is to determine how biodiversity dynamics, ecosystem processes, and abiotic factors interact...
  6. ncbi Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions
    Lance W Hahn
    Program in Human Genetics and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical School, Nashville, TN 37232 0700, USA
    Bioinformatics 19:376-82. 2003
    ..be dependent on other genetic variations (gene-gene interaction or epistasis) and environmental factors (gene-environment interaction)...
  7. ncbi Epigenetics and the environment: emerging patterns and implications
    Robert Feil
    Institute of Molecular Genetics IGMM, CNRS UMR 5535 and University of Montpellier, 1919 Route de Mende, 34293 Montpellier, France cnrs fr
    Nat Rev Genet 13:97-109. 2011
    ..These have implications for structuring future research and understanding disease and development...
  8. pmc Genomic expression programs in the response of yeast cells to environmental changes
    A P Gasch
    Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305 5428, USA
    Mol Biol Cell 11:4241-57. 2000
    ..Physiological themes in the genomic responses to specific environmental stresses provided insights into the effects of those stresses on the cell...
  9. ncbi Phenotypic diversity, population growth, and information in fluctuating environments
    Edo Kussell
    Laboratory of Living Matter and Center for Studies in Physics and Biology, Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021 6399, USA
    Science 309:2075-8. 2005
    ..Here we show that stochastic switching can be favored over sensing when the environment changes infrequently. The optimal switching rates then mimic the statistics of environmental changes...
  10. ncbi Understanding physical activity environmental correlates: increased specificity for ecological models
    Billie Giles-Corti
    School of Population Health, The University of Western Australia, Perth, Australia
    Exerc Sport Sci Rev 33:175-81. 2005
    ..This selective review examines whether the predictive capacity of these models could be improved if behavior-specific measures of the environment were used to predict context-specific behaviors.
  11. ncbi Understanding environmental influences on walking; Review and research agenda
    Neville Owen
    Cancer Prevention Research Centre, School of Population Health, University of Queensland, Brisbane, Queensland, Australia
    Am J Prev Med 27:67-76. 2004
    ..Walking is the most common physical activity behavior of adults; environmental innovations may be able to influence rates of participation...
  12. pmc Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles
    Pablo Orozco-terWengel
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    Mol Ecol 21:4931-41. 2012
    ..generation sequencing of DNA pools (Pool-Seq) to identify alleles that are favourable in a novel laboratory environment and traced their trajectories during the adaptive process...
  13. pmc Use of global positioning systems to study physical activity and the environment: a systematic review
    Patricia J Krenn
    Institute of Sport Science, University of Graz, Austria
    Am J Prev Med 41:508-15. 2011
    ..The aim of this systematic review was to determine the capability of GPS to collect high-quality data on the location of activities in research on the relationship between physical activity and the environment.
  14. pmc An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus
    Chirag J Patel
    Department of Pediatrics and Medicine, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 5:e10746. 2010
    ..We conducted a pilot Environmental-Wide Association Study (EWAS), in which epidemiological data are comprehensively and systematically interpreted in a manner analogous to a Genome Wide Association Study (GWAS)...
  15. pmc Green space, urbanity, and health: how strong is the relation?
    Jolanda Maas
    NIVEL, Netherlands Institute for Health Services Research, PO Box 1568, 3500 BN Utrecht, Netherlands
    J Epidemiol Community Health 60:587-92. 2006
    To investigate the strength of the relation between the amount of green space in people's living environment and their perceived general health. This relation is analysed for different age and socioeconomic groups...
  16. ncbi Jack of all trades, master of some? On the role of phenotypic plasticity in plant invasions
    Christina L Richards
    Department of Ecology and Evolution, Stony Brook University, 650 Life Sciences, Stony Brook, NY 11794 5245, USA
    Ecol Lett 9:981-93. 2006
    ..This new framework can be applied when testing both ecological or evolutionary oriented hypotheses, and therefore promises to bridge the gap between the two perspectives...
  17. pmc Gene-environment interaction in yeast gene expression
    Erin N Smith
    Lewis Sigler Institute for Integrative Genomics and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America
    PLoS Biol 6:e83. 2008
    ..genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood...
  18. ncbi Correlates of adults' participation in physical activity: review and update
    Stewart G Trost
    School of Human Movement Studies, University of Queensland, Brisbane QLD 4072, Australia
    Med Sci Sports Exerc 34:1996-2001. 2002
    ..To review and update the evidence relating to the personal, social, and environmental factors associated with physical activity (PA) in adults...
  19. ncbi Abiotic stress, the field environment and stress combination
    Ron Mittler
    Department of Biochemistry and Molecular Biology, University of Nevada, Mail Stop 200, Reno, NV 89557, USA
    Trends Plant Sci 11:15-9. 2006
    ..Tolerance to a combination of different stress conditions, particularly those that mimic the field environment, should be the focus of future research programs aimed at developing transgenic crops and plants with enhanced ..
  20. ncbi Stochastic switching as a survival strategy in fluctuating environments
    Murat Acar
    Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Nat Genet 40:471-5. 2008
    ..Each phenotype was designed to confer a growth advantage over the other phenotype in a certain environment. When we compared the growth of two populations with different switching rates, we found that fast-switching ..
  21. ncbi Neighborhood environments and physical activity among adults in 11 countries
    James F Sallis
    Active Living Research, Department of Psychology, San Diego State University, San Diego, California 92103, USA
    Am J Prev Med 36:484-90. 2009
    ..Surveys were conducted in 11 countries using the same self-report environmental variables and the International Physical Activity Questionnaire, allowing analyses with pooled data...
  22. pmc Attractor dynamics in the hippocampal representation of the local environment
    Tom J Wills
    Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, UK
    Science 308:873-6. 2005
    ..This enables study of attractor dynamics in a cognitive representation and may correspond to the formation of distinct contexts in context-dependent memory...
  23. ncbi C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
    E R Sawin
    Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA
    Neuron 26:619-31. 2000
    ..The basal and enhanced slowing responses are distinct and separable neuromodulatory components of a genetically tractable paradigm of behavioral plasticity...
  24. ncbi Confounding factors in the detection of species responses to habitat fragmentation
    Robert M Ewers
    School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Biol Rev Camb Philos Soc 81:117-42. 2006
    ..a landscape-level phenomenon in which species that survive in habitat remnants are confronted with a modified environment of reduced area, increased isolation and novel ecological boundaries...
  25. ncbi Unravelling the effects of the environment and host genotype on the gut microbiome
    Aymé Spor
    Department of Microbiology, Cornell University, Ithaca, New York 14853, USA
    Nat Rev Microbiol 9:279-90. 2011
    ..In this Review, we describe how host genetics and the environment shape the microbiota, and how these three factors may interact in the context of chronic disease.
  26. ncbi Potential environmental determinants of physical activity in adults: a systematic review
    W Wendel-Vos
    Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Obes Rev 8:425-40. 2007
    ..However, most studies used cross-sectional designs and non-validated measures of environments and/or behaviour. Therefore, no strong conclusions can be drawn and more research of better quality is clearly needed...
  27. ncbi Genetics of mouse behavior: interactions with laboratory environment
    J C Crabbe
    Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, OR 97201, USA
    Science 284:1670-2. 1999
    ..Possible confounding influences of the laboratory environment were studied in several inbred strains and one null mutant by simultaneous testing in three laboratories on a ..
  28. ncbi Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation
    Luis López-Maury
    Department of Genetics, Evolution and Environment, UCL Cancer Institute, University College London, London WC1E 6BT, UK
    Nat Rev Genet 9:583-93. 2008
    ..insight into cellular strategies for keeping gene expression in tune with physiological needs dictated by the environment, promoting adaptation to both short- and long-term environmental changes...
  29. pmc Adaptation, plasticity, and extinction in a changing environment: towards a predictive theory
    Luis Miguel Chevin
    Division of Biology, Imperial College London, Silwood Park, United Kingdom
    PLoS Biol 8:e1000357. 2010
    ..The unusual rate and extent of anthropogenic alterations of the environment may exceed the capacity of developmental, genetic, and demographic mechanisms that populations have evolved to ..
  30. ncbi Freshwater biodiversity: importance, threats, status and conservation challenges
    David Dudgeon
    Department of Ecology and Biodiversity, The University of Hong Kong, Hong Kong SAR, China
    Biol Rev Camb Philos Soc 81:163-82. 2006
    ..Recognition of this need will require adoption of a new paradigm for biodiversity protection and freshwater ecosystem management - one that has been appropriately termed 'reconciliation ecology'...
  31. ncbi Morbidity is related to a green living environment
    J Maas
    EMGO Institute, VU University Medical Centre, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    J Epidemiol Community Health 63:967-73. 2009
    ..There is increasing evidence for a positive relation between green space in people's living environment and self-reported indicators of physical and mental health...
  32. ncbi Global dispersal of free-living microbial eukaryote species
    Bland J Finlay
    Centre for Ecology and Hydrology Windermere, Ferry House, Ambleside, Cumbria LA22 0LP, UK
    Science 296:1061-3. 2002
    ....
  33. ncbi Environmental correlates of physical activity in youth - a review and update
    I Ferreira
    Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands
    Obes Rev 8:129-54. 2007
    ..Low crime incidence (in adolescents) was characteristic of the neighbourhood environment associated with higher PA...
  34. ncbi Forecasting agriculturally driven global environmental change
    D Tilman
    Department of Ecology, Evolution and Behavior, University of Minnesota, 1987 Upper Buford Circle, St Paul, MN 55108, USA
    Science 292:281-4. 2001
    ..Significant scientific advances and regulatory, technological, and policy changes are needed to control the environmental impacts of agricultural expansion...
  35. ncbi The frontoparietal attention network of the human brain: action, saliency, and a priority map of the environment
    Radek Ptak
    Division of Neurorehabilitation, Geneva University Hospital, University of Geneva, Switzerland
    Neuroscientist 18:502-15. 2012
    ..to a central role of this region in the computation of a feature- and modality-independent priority map of the environment. The priority map integrates feature information elaborated in sensory cortex and top-down representations of ..
  36. ncbi The environment and schizophrenia
    Jim Van Os
    European Graduate School for Neuroscience, SEARCH, Maastricht University Medical Centre, 6200 MD Maastricht, The Netherlands
    Nature 468:203-12. 2010
    ..emphasized, onset is associated with environmental factors such as early life adversity, growing up in an urban environment, minority group position and cannabis use, suggesting that exposure may have an impact on the developing '..
  37. pmc Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution
    Matteo Fumagalli
    Scientific Institute IRCCS E Medea, Bioinformatic Lab, Bosisio Parini, Italy
    PLoS Genet 7:e1002355. 2011
    ..Furthermore, we show that the diversity of the local pathogenic environment is the predominant driver of local adaptation, and that climate, at least as measured here, only plays a ..
  38. ncbi Climate change and evolution: disentangling environmental and genetic responses
    P Gienapp
    Ecological Genetics Research Unit, Department of Biological and Environmental Sciences, PO Box 65, FI 00014 University of Helsinki, Finland
    Mol Ecol 17:167-78. 2008
    ..Hence, clear-cut evidence indicating a significant role for evolutionary adaptation to ongoing climate warming is conspicuously scarce...
  39. ncbi Climate change and distribution shifts in marine fishes
    Allison L Perry
    Centre for Ecology, Evolution and Conservation, School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
    Science 308:1912-5. 2005
    ..Further temperature rises are likely to have profound impacts on commercial fisheries through continued shifts in distribution and alterations in community interactions...
  40. ncbi Healthy nutrition environments: concepts and measures
    Karen Glanz
    Rollins School of Public Health, Emory University, 1518 Clifton Road, NE, Room 526, Atlanta, GA 30322, USA
    Am J Health Promot 19:330-3, ii. 2005
    The authors provide a conceptual model of a healthy nutrition environment, then review the types of measures required to assess various aspects of this environment...
  41. pmc Home environment relationships with children's physical activity, sedentary time, and screen time by socioeconomic status
    Pooja S Tandon
    Seattle Children s Research Institute, M S CW8 6, P, O, Box 5371, Seattle, WA 98145 5005, USA
    Int J Behav Nutr Phys Act 9:88. 2012
    ..We aimed to determine if home physical activity (PA) environments differed by SES and to explore home environment mediators of the relation of family SES to children's PA and sedentary behavior.
  42. pmc School and residential neighborhood food environment and diet among California youth
    Ruopeng An
    RAND Corporation, Santa Monica, California, USA
    Am J Prev Med 42:129-35. 2012
    ..For youth, empirical evidence for any particular hypothesis remains limited...
  43. ncbi Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment
    Martin H Rau
    Department of Systems Biology, Technical University of Denmark, 2800 Lyngby, Denmark
    Environ Microbiol 14:2200-11. 2012
    ..Finally, we also describe the complete genome of this highly adapted pathogenic strain of P.aeruginosa to strengthen the genetic basis, which serves to help our understanding of microbial evolution in a natural environment.
  44. pmc Vulnerability genes or plasticity genes?
    J Belsky
    Institute for the Study of Children, Families and Social Issues, Birkbeck University of London, London, UK
    Mol Psychiatry 14:746-54. 2009
    ..as particularly vulnerable to adversity, informs virtually all psychiatric research on behavior-gene-environment (G x E) interaction...
  45. pmc A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry
    Laramie E Duncan
    Harvard School of Public Health, Massachusetts General Hospital, McLean Hospital, Harvard Medical School, Belmont, USA
    Am J Psychiatry 168:1041-9. 2011
    Gene-by-environment interaction (G×E) studies in psychiatry have typically been conducted using a candidate G×E (cG×E) approach, analogous to the candidate gene association approach used to test genetic main effects...
  46. ncbi Antibiotic resistance in the environment: a link to the clinic?
    Gerard D Wright
    M G DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada L8N 3Z5
    Curr Opin Microbiol 13:589-94. 2010
    ..Understanding the extent of the environmental resistome and its mobilization into pathogenic bacteria is essential for the management and discovery of antibiotics...
  47. ncbi The mental and physical health outcomes of green exercise
    Jules Pretty
    Department of Biological Sciences, University of Essex, Colchester, UK
    Int J Environ Health Res 15:319-37. 2005
    ..We conclude that green exercise has important public and environmental health consequences...
  48. ncbi Individual, social, and physical environment factors associated with electronic media use among children: sedentary behavior at home
    Joanna Granich
    School of Sport Science, Exercise, and Health, The University of Western Australia, Perth, Australia
    J Phys Act Health 8:613-25. 2011
    Individual, home social and physical environment correlates of electronic media (EM) use among children were examined and pattern of differences on school and weekend days.
  49. pmc Genes and social behavior
    Gene E Robinson
    Department of Entomology, University of Illinois at Urbana Champaign, 505 South Goodwin Avenue, Urbana, IL 61801, USA
    Science 322:896-900. 2008
    ..We also discuss how evolutionary changes in genomic elements influence social behavior and outline prospects for a systems biology of social behavior...
  50. pmc Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactions
    David Duneau
    University of Basel, Zoological Institute, Vesalgasse 1, Basel, Switzerland
    BMC Biol 9:11. 2011
    ....
  51. pmc Using environmental correlations to identify loci underlying local adaptation
    Graham Coop
    Department of Evolution and Ecology and Center for Population Biology, University of California, Davis, Calfornia 95616, USA
    Genetics 185:1411-23. 2010
    ..Software is available at http://www.eve.ucdavis.edu/gmcoop/...
  52. ncbi Phenotypic plasticity in the interactions and evolution of species
    A A Agrawal
    Department of Botany, University of Toronto, 25 Willcocks Street, Toronto, ON M5S 3B2, Canada
    Science 294:321-6. 2001
    ..Taken together, phenotypic responses in species interactions represent modifications that can lead to reciprocal change in ecological time, altered community patterns, and expanded evolutionary potential of species...
  53. ncbi Adaptive prediction of environmental changes by microorganisms
    Amir Mitchell
    Department of Molecular Genetics, Weizmann Institute of Science Rehovot 76100, Israel
    Nature 460:220-4. 2009
    ..Our work indicates that environmental anticipation is an adaptive trait that was repeatedly selected for during evolution and thus may be ubiquitous in biology...
  54. pmc Gene duplication as a mechanism of genomic adaptation to a changing environment
    Fyodor A Kondrashov
    Institucio Catalana de Recerca i Estudis Avancats, Centre for Genomic Regulation CRG and Universitat Pompeu Fabra, 88 Dr Aiguader, Barcelona 08003, Spain
    Proc Biol Sci 279:5048-57. 2012
    ....
  55. ncbi Environment can alter selection in host-parasite interactions
    Justyna Wolinska
    Ludwig Maximilians Universitat, Department Biologie II, Evolutionsökologie, Grosshaderner Str 2, D 82152 Planegg Martinsried, Germany
    Trends Parasitol 25:236-44. 2009
    ..Infections measured under laboratory conditions have shown that the environment in which hosts and parasites interact might substantially affect the strength and specificity of selection...
  56. pmc C. elegans dauer formation and the molecular basis of plasticity
    Nicole Fielenbach
    Huffington Center on Aging, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Genes Dev 22:2149-65. 2008
    ..dynamic, and complex, all animals have evolved remarkable abilities to cope with changes in their external environment and internal physiology...
  57. ncbi Motor protein KIF1A is essential for hippocampal synaptogenesis and learning enhancement in an enriched environment
    Makoto Kondo
    Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo 113 0033, Japan
    Neuron 73:743-57. 2012
    ..of kinesin superfamily motor protein 1A (KIF1A) was observed in the hippocampi of mice kept in an enriched environment and, in hippocampal neurons in vitro, BDNF increased the levels of KIF1A and of KIF1A-mediated cargo transport...
  58. pmc The influence of oral health conditions, socioeconomic status and home environment factors on schoolchildren's self-perception of quality of life
    Janice S Paula
    Department of Community Dentistry, Division of Health Education and Health Promotion, Piracicaba Dental School, P, O, Box 52, University of Campinas UNICAMP, 13414 903, Piracicaba, SP, Brazil
    Health Qual Life Outcomes 10:6. 2012
    The objective this study was to investigate the influence of clinical conditions, socioeconomic status, home environment, subjective perceptions of parents and schoolchildren about general and oral health on schoolchildren's oral health-..
  59. pmc Neuronal basis of sequential foraging decisions in a patchy environment
    Benjamin Y Hayden
    Department of Neurobiology, Duke University School of Medicine, Durham, North Carolina, USA
    Nat Neurosci 14:933-9. 2011
    ..These findings portend an understanding of the neural basis of foraging decisions and endorse the unification of theoretical and experimental work in ecology and neuroscience...
  60. ncbi Gene-environment interactions in human diseases
    David J Hunter
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115, USA
    Nat Rev Genet 6:287-98. 2005
    Studies of gene-environment interactions aim to describe how genetic and environmental factors jointly influence the risk of developing a human disease...
  61. pmc Neighborhood food environment and walkability predict obesity in New York City
    Andrew Rundle
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Environ Health Perspect 117:442-7. 2009
    Differences in the neighborhood food environment may contribute to disparities in obesity.
  62. ncbi Bounded integration in parietal cortex underlies decisions even when viewing duration is dictated by the environment
    Roozbeh Kiani
    Howard Hughes Medical Institute, National Primate Research Center, and Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195, USA
    J Neurosci 28:3017-29. 2008
    ..Under many natural circumstances and in many laboratory settings, the environment, rather than the subject, controls the stimulus duration...
  63. ncbi The epigenome: archive of the prenatal environment
    Bastiaan T Heijmans
    Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Epigenetics 4:526-31. 2009
    ..Well-designed epigenome-wide studies will be crucial in creating a catalog of epigenomic regions that are sensitive to the prenatal environment to evaluate developmental influences on common human disease.
  64. ncbi Relationship between the physical environment and physical activity in older adults: a systematic review
    Jelle Van Cauwenberg
    Department of Human Biometry and Biomechanics, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussel, Belgium
    Health Place 17:458-69. 2011
    ..aims to provide a comprehensive overview of the literature concerning the relationship between the physical environment and PA in older adults. A systematic literature search resulted in the inclusion of 31 articles...
  65. ncbi The Power of Food Scale. A new measure of the psychological influence of the food environment
    Michael R Lowe
    Department of Psychology, Drexel University, Philadelphia, PA 19102, USA
    Appetite 53:114-8. 2009
    ..The PFS may be useful as a measure of the hedonic impact of food environments replete with highly palatable foods...
  66. pmc Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics
    Tamara B Harris
    Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892 9205, USA
    Am J Epidemiol 165:1076-87. 2007
    In anticipation of the sequencing of the human genome and description of the human proteome, the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik) was initiated in 2002...
  67. ncbi Anthropogenic environmental change and the emergence of infectious diseases in wildlife
    P Daszak
    Institute of Ecology, University of Georgia, Athens GA 30602, USA
    Acta Trop 78:103-16. 2001
    ....
  68. pmc The environment and susceptibility to schizophrenia
    Alan S Brown
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY 10032, USA
    Prog Neurobiol 93:23-58. 2011
    ..and more rigorous epidemiologic investigations, and research on translational and clinical neuroscience, gene-environment interactions, epigenetics, developmental trajectories and windows of vulnerability, are elaborated upon...
  69. ncbi Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders
    Martha R Herbert
    TRANSCEND Research Program, Pediatric Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Curr Opin Neurol 23:103-10. 2010
    ..This review presents a rationale and evidence for contributions of environmental influences and environmentally vulnerable physiology to autism spectrum disorders (ASDs)...
  70. ncbi Measuring the food environment using geographical information systems: a methodological review
    Hélène Charreire
    UMR INSERM U 557 INRA U 1125 CNAM, University Paris 13, CRNH IdF, Bobigny, France
    Public Health Nutr 13:1773-85. 2010
    Through a literature review, we investigated the geographic information systems (GIS) methods used to define the food environment and the types of spatial measurements they generate.
  71. ncbi Twin studies in autoimmune disease: genetics, gender and environment
    Dimitrios P Bogdanos
    Institute of Liver Studies, Liver Immunopathology, King s College London School of Medicine at King s College Hospital, London, UK
    J Autoimmun 38:J156-69. 2012
    ..This review will examine the literature surrounding twin studies in autoimmune disease including discussions of genetics and gender...
  72. pmc Unhealthy landscapes: Policy recommendations on land use change and infectious disease emergence
    Jonathan A Patz
    Center for Sustainability and the Global Environment SAGE, Nelson Institute for Environmental Studies and the Department of Population Health Sciences, University of Wisconsin, Madison, 53726 4087, USA
    Environ Health Perspect 112:1092-8. 2004
    ....
  73. ncbi Built environment, physical activity, and obesity: what have we learned from reviewing the literature?
    Ding Ding
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
    Health Place 18:100-5. 2012
    To evaluate the growing literature on the built environment and physical activity/obesity, we conducted a review of review papers...
  74. ncbi Epigenetic programming of neurodegenerative diseases by an adverse environment
    Olena Babenko
    Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, Canada
    Brain Res 1444:96-111. 2012
    Experience and environment can critically influence the risk and progression of neurodegenerative disorders...
  75. pmc Flowering time quantitative trait Loci analysis of oilseed brassica in multiple environments and genomewide alignment with Arabidopsis
    Y Long
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, China
    Genetics 177:2433-44. 2007
    ..Five to 18 QTL at a statistically significant level (SL-QTL) were detected in each environment and, on average, two new SL-QTL were discovered with each added environment...
  76. ncbi On the generality of the latitudinal diversity gradient
    Helmut Hillebrand
    Department of Limnology, Evolutionary Biology Centre, University of Uppsala, Norr Malma 4200, S 76173 Norrtalje, Sweden
    Am Nat 163:192-211. 2004
    ..This analysis is the first to describe these general and significant patterns, which have important consequences for models aiming to explain the latitudinal gradient...
  77. ncbi Limiting the impact of light pollution on human health, environment and stellar visibility
    Fabio Falchi
    Istituto di Scienza e Tecnologia dell Inquinamento Luminoso, Via Roma 13, I 36106 Thiene, Italy
    J Environ Manage 92:2714-22. 2011
    ..This increase will exacerbate known and possible unknown effects of light pollution on human health, environment and on visual perception of the Universe by humans...
  78. ncbi Environmental enrichment, prefrontal cortex, stress, and aging of the brain
    Gregorio Segovia
    Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, S N, Madrid 28040, Spain
    J Neural Transm 116:1007-16. 2009
    As a result of living in an enriched environment, the brain of animals undergoes molecular and morphological changes leading to improvements in learning and memory...
  79. ncbi Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction
    Avshalom Caspi
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Biol Psychiatry 57:1117-27. 2005
    ..The vast majority of cannabis users do not develop psychosis, however, prompting us to hypothesize that some people are genetically vulnerable to the deleterious effects of cannabis...
  80. ncbi Environmental and psychosocial correlates of accelerometer-assessed and self-reported physical activity in Belgian adults
    Delfien Van Dyck
    Fund for Scientific Research Flanders, Ghent, Belgium
    Int J Behav Med 18:235-45. 2011
    ..To develop effective interventions to increase PA, it is necessary to understand the most important PA correlates and to investigate whether correlates are similar in different population subgroups...
  81. ncbi Atopic disease, immune system, and the environment
    Salvatore Leonardi
    Department of Pediatrics, Catania University, Catania, Italy
    Allergy Asthma Proc 28:410-7. 2007
    ..of allergic respiratory diseases observed in the last 20 years seems to be associated with changes of environment and lifestyle, which favor a delayed acquisition of Th1 function in childhood...
  82. pmc An approximately Bayesian delta-rule model explains the dynamics of belief updating in a changing environment
    Matthew R Nassar
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 30:12366-78. 2010
    ..appropriate beliefs about variables needed for effective decision making can be difficult in a dynamic environment. One key issue is the amount of influence that unexpected outcomes should have on existing beliefs...
  83. pmc Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits
    Avshalom Caspi
    Department of Psychology, and Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA
    Am J Psychiatry 167:509-27. 2010
    ..The study of such Gene-by-Environment (GxE) interactions has gained momentum...
  84. pmc The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions
    Marilyn C Cornelis
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115
    Genet Epidemiol 34:364-72. 2010
    ..However, the role of environment and its potential to interact with key loci has not been adequately addressed in most GWAS...
  85. ncbi Epigenetic mechanisms and cancer: an interface between the environment and the genome
    Zdenko Herceg
    Epigenetics Group, International Agency for Research on Cancer IARC, Lyon, France
    Epigenetics 6:804-19. 2011
    Although epidemiological studies support the role of environment in a wide range of human cancers, the precise mechanisms by which environmental exposures promote cancer development and progression remain poorly understood...
  86. pmc Gene--environment-wide association studies: emerging approaches
    Duncan Thomas
    Medicine, University of Southern California, 1540 Alcazar Street, CHP 220, Los Angeles, California 90089 9011, USA
    Nat Rev Genet 11:259-72. 2010
    ..This unexplained heritability could be partly due to gene--environment (G×E) interactions or more complex pathways involving multiple genes and exposures...
  87. ncbi Clonal adaptive radiation in a constant environment
    Ram Maharjan
    School of Molecular and Microbial Biosciences, University of Sydney, Sydney, New South Wales 2006, Australia
    Science 313:514-7. 2006
    ..The multidirectional exploration of fitness space is an underestimated ingredient to bacterial success even in unstructured environments...
  88. ncbi Adaptation to an extraordinary environment by evolution of phenotypic plasticity and genetic assimilation
    Russell Lande
    Division of Biology, Imperial College London, Silwood Park, Ascot, Berkshire, UK
    J Evol Biol 22:1435-46. 2009
    Adaptation to a sudden extreme change in environment, beyond the usual range of background environmental fluctuations, is analysed using a quantitative genetic model of phenotypic plasticity...
  89. ncbi A serpentinite-hosted ecosystem: the Lost City hydrothermal field
    Deborah S Kelley
    School of Oceanography, University of Washington, Seattle, WA 98195, USA
    Science 307:1428-34. 2005
    ....
  90. ncbi Functional traits and environmental filtering drive community assembly in a species-rich tropical system
    Edwin Lebrija-Trejos
    Wageningen University, Forest Ecology and Forest Management Group, Centre for Ecosystem Studies, P O Box 47, 6700 AA, Wageningen, The Netherlands
    Ecology 91:386-98. 2010
    ..measurements and scale up from species to community level and because the functional traits' significance is environment dependent...
  91. pmc Gene X environment interaction of vigorous exercise and body mass index among male Vietnam-era twins
    Jeanne M McCaffery
    Weight Control and Diabetes Research Center, Brown Medical School and The Miriam Hospital, Providence, RI 02903, USA
    Am J Clin Nutr 89:1011-8. 2009
    ..However, twin models that incorporate a gene-environment correlation and gene x environment interaction have not been applied to elucidate specific environmental ..
  92. ncbi Immigration history controls diversification in experimental adaptive radiation
    Tadashi Fukami
    Department of Zoology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA
    Nature 446:436-9. 2007
    ..These results demonstrate that immigration and diversification are tightly linked processes, with small differences in immigration history greatly affecting the evolutionary emergence of diversity...
  93. pmc Prion transmission: prion excretion and occurrence in the environment
    Kevin C Gough
    School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, UK
    Prion 4:275-82. 2010
    ..The cycle of "uptake of prion from the environment--widespread in vivo prion dissemination--prion excretion--prion persistence in the environment" is likely to ..
  94. ncbi Global patterns in biodiversity
    K J Gaston
    Department of Animal and Plant Sciences, University of Sheffield, UK
    Nature 405:220-7. 2000
    ..Theory is, however, developing rapidly, improving in its internal consistency, and more readily subjected to empirical challenge...
  95. ncbi Gene-environment interactions in obesity
    Marion M Hetherington
    Institute of Psychological Sciences, University of Leeds, Leeds, UK
    Forum Nutr 63:195-203. 2010
    ..Common obesity is polygenic, involving complex gene-gene and gene-environment interactions, and it is these interactions that produce the multi-factorial obese phenotypes...
  96. ncbi Escherichia coli mechanisms of copper homeostasis in a changing environment
    Christopher Rensing
    Department of Soil, Water, and Environmental Science, University of Arizona, Shantz Bld 38, Rm 429, Tucson, AZ 85721, USA
    FEMS Microbiol Rev 27:197-213. 2003
    ..Pathways of copper uptake and intracellular copper handling are still not identified in E. coli...
  97. ncbi The presence of the glycolysis operon in SAR11 genomes is positively correlated with ocean productivity
    M S Schwalbach
    Oregon State University, Department of Microbiology, 220 Nash Hall, Corvallis, OR 97331, USA
    Environ Microbiol 12:490-500. 2010
    ..Our results indicated that glycolysis is a variable metabolic property of SAR11 metabolism and suggest that glycolytic SAR11 are more common in productive marine environments...
  98. pmc Specialization can drive the evolution of modularity
    Carlos Espinosa-Soto
    Department of Biochemistry, University of Zurich, Zurich, Switzerland
    PLoS Comput Biol 6:e1000719. 2010
    ..We also show how modularity can facilitate co-option, the utilization of existing gene activity to build new gene activity patterns, a frequent feature of evolutionary innovations...
  99. pmc Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments
    Harold N Frazier
    Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA 98195, USA
    Curr Biol 19:859-63. 2009
    ..Such parental effects are adaptive for the offspring if the future environment is similar to the current one but can be maladaptive otherwise [11]...
  100. pmc Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms
    Kerry J Ressler
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 954 Gatewood Drive, Atlanta, GA 30329, USA
    Am J Med Genet B Neuropsychiatr Genet 153:812-24. 2010
    Gene x environment (G x E) interactions mediating depressive symptoms have been separately identified in the stress-sensitive serotonergic (5-HTTLPR) and corticotropin-releasing hormone (CRHR1) systems...
  101. pmc Gene-environment interactions in Parkinson's disease: the importance of animal modeling
    M P Horowitz
    Medical Scientist Training Program, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Clin Pharmacol Ther 88:467-74. 2010
    ..We argue that animal modeling will become increasingly important in attempting to elucidate gene-environment interactions, to define pathogenic mechanisms, and to provide a platform for testing of targeted therapeutic ..

Research Grants74

  1. Molecular Basis of E. coli Adhesins in Bladder Disorders
    Scott J Hultgren; Fiscal Year: 2013
    ....
  2. Mechanisms for Cardiovascular Effects of air pollutants: Effect of Age and Sex
    BRITT HOLMEN; Fiscal Year: 2010
    ..Despite the belief that biofuels may be better for the environment and for human health, there is very limited information about the biological effects of biodiesel emissions so ..
  3. Chronic Granulomatous Lung Inflammation Elicited by Carbon Nanotubes
    Mary Jane Thomassen; Fiscal Year: 2013
    ..In summary, this unique investigation of MWCNT-elicited granulomatous lung disease is well suited for student participation in an area with environmental impact on human disease. ..
  4. The Toxic Environment and the Epigenetics of Fetal Growth
    HEATHER HERSON BURRIS; Fiscal Year: 2013
    ..the skills and experience needed to achieve success as an independent investigator studying the role of the environment and epigenetic mechanisms in birth outcomes...
  5. Nanodiagnostics and Nanotherapeutics: Building Research Ethics and Oversight
    Susan M Wolf; Fiscal Year: 2010
    ..abstract_text> ..
  6. Transgenerational epigenetic inheritance of allergy in a multigenerational cohort
    WILFRIED JJ KARMAUS; Fiscal Year: 2013
    ..In addition, the combined effects of genes and the environment are more strongly associated with allergy than genes alone...
  7. A semi field trial test on efficacy of transgenic antimalarial biocontrol fungi
    Raymond J St Leger; Fiscal Year: 2013
    ..organisms) projects go through a review process that includes semi-field studies in a contained near-natural environment as a prerequisite for an open field release...
  8. 15th International Workshop on Ataxia-Telangiectasia and ATM to be held in India
    Tej K Pandita; Fiscal Year: 2012
    ..This will be the first A-T Workshop that provides a forum to discuss the near term potential for applying the results from basic ATM studies to possible A-T clinical treatment trials and, in the future, other neurological diseases. ..
  9. In Vivo Measures of Vocal Function Response to Environmental Conditions
    MARY JOYCE SANDAGE; Fiscal Year: 2012
    ..This novel application of concurrent measures of laryngeal environment temperature (pharyngeal thermister temperature probe and infrared thermal imaging) with clinical measures of ..
  10. Fc receptor targeted therapy for immune hemolytic anemia
    Periasamy Selvaraj; Fiscal Year: 2009
    ..a.* Does this project have an actual or potential impact on m Yes l No the environment? 4.b. If yes, please explain: 4.c...
  11. Porphyromonas gingivalis Horizontal DNA Transfer and Genetic Variation
    Gena D Tribble; Fiscal Year: 2013
    ..are their only habitat, and evolution in these bacteria is in response to selective pressure from the host environment. As each human host represents a unique ecological niche, bacterial virulence factors that contribute to ..
  12. Environmental exposure to metal mixtures and kidney disease
    Mary Fox; Fiscal Year: 2009
    ..The National Institute for Environmental Health Sciences stated in its 2006-2011 Strategic Plan that maximal public health impact depends on conducting research relevant to societal decision making. ..
  13. Restoration of Fecal Continence in Aging IAS
    Khalil N Bitar; Fiscal Year: 2012
    ..a.* Does this project have an actual or potential impact on m Yes l No the environment? 4.b. If yes, please explain: 4.c...
  14. Transcriptional Regulation of Retinal Development
    Mengqing Xiang; Fiscal Year: 2012
    ..a. * Does this project have an actual or potential impact on Yes No the environment? 4.b. If yes, please explain: 4.c...
  15. EID - Effects of avian migration & anthropogenic change on the distribution & tra
    Thomas Smith; Fiscal Year: 2009
    ..Finally, we will share our results with public health organizations and the scientific community in a timely fashion in order to maximize the public good. ..
  16. Evaluation, Validation, and Implementation of Acoustic Droplet Ejector Technology
    Martin E Adelson; Fiscal Year: 2010
    ....
  17. Exploring Interactions between Folate and Environmental Risk Factors for Autism
    REBECCA JEAN SCHMIDT; Fiscal Year: 2013
    ..Prenatal nutrition and nutrient-environment interactions have been understudied in relation to autism etiology and risk...
  18. 3-Dimensional Imaging of Biomaterials on the Nanoscale with Mass Spectrometry
    Nicholas Winograd; Fiscal Year: 2010
    ..Samples are analyzed without significant chemical usage, and power consumption, associated mostly with vacuum pumps, is modest during and after spectrometer evacuation. ..
  19. EnerCage: A Scalable Array of Intelligent Wireless Sensor Modules to Energize and
    Maysam Ghovanloo; Fiscal Year: 2010
    ..Therefore it permits multichannel recordings for many hours by eliminating the need for carrying batteries on the animal body in large and completely enclosed experimental arenas, similar to rodents'natural habitat. ..
  20. Using genomics to understand physiologic water conservation in desert rodents
    MATTHEW MACMANES; Fiscal Year: 2013
    ..Within the set of genes that are differentially expressed in the dry season, those that are specific to desert-adapted species are likely critical for persistence in desert environments (e.g., likely underlie anuria). ..
  21. AvanceIII 700MHz NMR spectrometer with cryogenic probe
    James J Chou; Fiscal Year: 2010
    ..The proposed 700 MHz NMR spectrometer would provide us sufficient instrumentation to move the above studies forward, while maintaining the postdoctoral fellow positions involved in these projects;it has no environmental impact. ..
  22. Environmental Mutagen Society 2011 Annual Meeting
    CATHERINE G B KLEIN; Fiscal Year: 2011
    ..The meetings also provide a forum in which students, postdoctoral fellows, and early career investigators can share information with established scientists through formal scientific sessions and informal interactions. ..
  23. Ecological impacts of forest disturbance on La Crosse encephalitis virus dynamics
    MARIA RICHETTA CAMILLE HARRIS; Fiscal Year: 2010
    ..We will also perform experiments to assess how efficiently mosquito species can transmit this virus. ..
  24. Colloidal Quantum Dot/Well Near-Infrared NanoLabels
    Hua Mao; Fiscal Year: 2010
    ..Unlike zero tolerance of Cd, Hg and Pb in today's regulation environment in advanced countries, human body can tolerate a small amount of indium, arsenic and selenium...
  25. The role of polysaccharide surface capsules in Bacteroides glycan degradation
    Eric C Martens; Fiscal Year: 2013
    ....
  26. Adaptive Evolutionary Responses of White-footed Mice (Peromyscus leucopus) to Urb
    Jason Munshi-South; Fiscal Year: 2012
    ....
  27. Identification of bacteria-associated cues that regulate hatching of Aedes aegypt
    Loganathan Ponnusamy; Fiscal Year: 2013
    ..Moreover, the project will provide tools and reagents for future research on the physiological events during the transition from embryo to neonate, including gene expression patterns and studies of sensory physiology. ..
  28. Linking infectious disease dynamics to seasonal animal movements
    REBECCA ANNE BARTEL; Fiscal Year: 2010
    ..and duration of time spent in a given habitat affect parasite transmission and accumulation in the hosts'environment. To examine how the costs of infection impact host migratory success, I will incorporate field data analysis ..
  29. Aerobic Growth of Anaerobic Pathogens
    ABRAHAM LINCOLN SONENSHEIN; Fiscal Year: 2013
    ..Given that the normal habitat for these bacteria is the anaerobic environment of the large intestine, it is remarkable that our preliminary results have shown that mutants of B...
  30. A Unique Natural Model for Studying the Mechanisms Underlying Social Behavior
    Donna L Maney; Fiscal Year: 2013
    ..Here, we will study these influences in an animal model with a natural polymorphism that provides a unique opportunity to characterize the processes underlying aggression and parenting. ..
  31. Eosinophils support nematode infection
    Judith A Appleton; Fiscal Year: 2012
    ..Finally, our studies have relevance to other chronic diseases in which eosinophils also populate the microenvironment, including obesity, cancer, and allergy. ..
  32. The Genetics and Evolution of Extreme Body Size in Mice from Gough Island
    Bret A Payseur; Fiscal Year: 2013
    ..In addition, our results will help situate phenotypic differences among laboratory mouse strains used as models for disease within the larger context of natural trait variation. ..
  33. Enhanced Recovery of Pharmaceutical Solvent driven by EPA Initiative
    JOHN J BOWSER; Fiscal Year: 2013
    ..The goal is water/methanol selectivity greater than 15.0. A parallel goal is 50% savings compared to molecular sieves. ..
  34. How economic and neighborhood factors modify effects of school obesity policies
    DANIEL TABER; Fiscal Year: 2012
    ..proposed training will include: 1) formal coursework in system dynamics, 2) one-on-one training in economic and environment policy initiatives, and 3) one-on-one training in economic methods of studying disparities and policy ..
  35. New Tools for Understanding the Composition and Dynamics of Microbial Communities
    Robin Knight; Fiscal Year: 2012
    ..within an individual, in transmission between individuals, and in transmission between humans and the environment. This project is directly responsive to the Roadmap RFA for Development of New tools for Computational Analysis ..
  36. Malaria in Africa: A History of Infections and Interventions, 1900-2010
    JAMES LEWIS ADRIAN WEBB; Fiscal Year: 2012
    ..The United States Government, through the President's Malaria Initiative, is actively engaged in malaria control in Africa. This project is squarely aligned with the larger mission of the National Institutes of Health. ..
  37. Development of a system (devices and protocols) to improve biospecimen preservati
    BRIAN HRUDKA; Fiscal Year: 2012
    ..National Cancer Institute (NCI), Office of Biorepositories and Biospecimen Research (OBBR) website. ..
  38. XXIst North American Testis Workshop
    John R McCarrey; Fiscal Year: 2011
    ....
  39. 2013 Mycotoxins and Phycotoxins Gordon Research Conference &Gordon Research Semi
    Gary A Payne; Fiscal Year: 2013
    ..and students who are all ultimately focused on solving similar problems --- ensuring the health of the environment and the safety and security of the food supply...
  40. The Genetics of Parallel Reproductive Isolation in Stickleback Species Pairs
    Catherine L Peichel; Fiscal Year: 2012
    ..Thus, sticklebacks provide an excellent vertebrate model system for studying the genetic architecture of phenotypic variation that has direct relevance to similar studies in humans. ..
  41. Evolution of Avian Photopigments: From Sequences to Color Vision
    NATASHA IVONNE BLOCH; Fiscal Year: 2013
    ..Here, "natural experiments" provided by evolution, give us the opportunity to study the mechanisms of spectral tuning in visual pigments. ..
  42. 2011 Mycotoxins and Phycotoxins Gordon Research Conference
    James J Pestka; Fiscal Year: 2011
    ..scientists and students who are all ultimately focused on solving similar problems--ensuring the health of the environment and the safety and security of the food supply...
  43. Neurogenomics of Social Behavior: Songbird Models
    David F Clayton; Fiscal Year: 2010
    ..Probing these links requires appropriate model organisms. This research aims to exploit natural advantages of songbirds as models for social behavior, leveraging recent progress with songbird neurobiology and genomics. ..
  44. Remediation of Word Processing and Short-Term Memory Deficits in Aphasia
    Nadine Martin; Fiscal Year: 2009
    ..a.* Does this project have an actual or potential impact on m Yes l No the environment? 4.b. If yes, please explain: 4.c...
  45. Jefferson Alumni Hall Modernization of Cage Sanitation Facility
    Judith S Daviau; Fiscal Year: 2013
    ..The procurement and installation of this equipment will result in increased personnel efficiency, less down time, significant operational savings and decreased negative environmental impact. ..
  46. Behavioral dynamics of Langerhans cells in skin
    Akira Takashima; Fiscal Year: 2010
    ..Our study should provide important insights into the behavioral biology of LCs and the pathophysiology of skin disease in which LCs play pathogenic or protective roles. ..
  47. How economic and neighborhood factors modify effects of school obesity policies
    DANIEL TABER; Fiscal Year: 2013
    ..proposed training will include: 1) formal coursework in system dynamics, 2) one-on-one training in economic and environment policy initiatives, and 3) one-on-one training in economic methods of studying disparities and policy ..
  48. Predation, habitat drying, and habitat size and production of vector mosquitoes
    Steven A Juliano; Fiscal Year: 2012
    ..Because these encephalitis vectors are widespread in the eastern US, this research is relevant to questions concerning how to target man made containers for source reduction or larviciding to minimize production of specific vectors. ..
  49. Genetic basis of salt tolerance in Anopheles gambiae s.l.
    Nora J Besansky; Fiscal Year: 2013
    ..trait using next generation genomic tools lays the groundwork for future efforts to understand the mechanisms by which these vector mosquitoes adapt to a heterogeneous and changing environment, opening up new avenues of vector control.
  50. RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES
    Max Costa; Fiscal Year: 2013
    ..abstract_text> ..
  51. Roots of Rainforest Medicine
    ROBERT ALLEN VOEKS; Fiscal Year: 2010
    ..Finally, this work documents how and why the legacy of centuries of ethnomedicinal wisdom is dying out with this generation of elders. ..
  52. Exposure-induced Systemic Oxidative Stress in Children with Asthma
    MELINDA SUE BUTSCH KOVACIC; Fiscal Year: 2010
    ..Consequently, these and planned future efforts will underscore the importance of environmental exposures in asthma treatment, development of diagnostic tools and new evidenced-based environmental policies. ..
  53. MRI Scanner (3T) for Research in Catastrophic Diseases of Childhood
    Robert J Ogg; Fiscal Year: 2010
    ..Jude Children's Research Hospital within 2 years, support construction activities at St. Jude, and strengthen the employment position of Siemens Medical Solutions in the United States. ..
  54. Identification of factors that control Mycobacterium tuberculosis biofilm growth
    Anil Kumar Ojha; Fiscal Year: 2010
    ..tuberculosis by studying its growth and development in biofilms- the surface attached multicellular structures with significantly more drug tolerant persisters than planktonic cultures. ..
  55. Ochlerotatus japonicus: Ecology of an Invasive Mosquito
    RICHARD FALCO; Fiscal Year: 2005
    ..Such information is critical to understanding how a new vector becomes established in a landscape where its exposure to other circulating pathogens may facilitate its transition to a primary zoonotie vector. ..
  56. A 15 Tesla MRI and MRS System for Small Animals
    John C Gore; Fiscal Year: 2010
    ..The system has been designed to have minimal environmental impact and the major parts will be recycled at the end of its useful life. ..
  57. EPIGENETICS, CHROMATIN &TRANSCRIPTION
    Shelley L Berger; Fiscal Year: 2011
    ....
  58. An Integrated and Individual Tick Management Program to Reduce Risk of Lyme Disea
    Scott C Williams; Fiscal Year: 2013
    ..Keywords: blacklegged tick;ITM;Lyme disease;biological control;landscape management;blood-meal analysis;pathogen screening;cost-benefit analysis;deer management;decision support system. ..
  59. Malaria Vector Biology in Brazil: Genetics and Ecology
    Jan E Conn; Fiscal Year: 2012
    ....
  60. Cytoskeletal Regulation of T cell Motility and Synaptic Signaling
    Matthew F Krummel; Fiscal Year: 2013
    ..This project will delve into how the T cell works in its native habitat and will reveal nvel mechanisms that regulate immunity and tolerance. ..
  61. Drosophila Genomics Resource Center
    PETER T CHERBAS; Fiscal Year: 2013
    ..The DGRC has 7500 users (cumulative over 8 years) in 3400 laboratories, adds 600 users per year, and makes >2000 shipments of materials per year. User surveys document the importance of these efforts to Drosophila researchers. ..
  62. Development of Rechargeable Batteries for BTE Cochlear Devices
    SIMON K NIEH; Fiscal Year: 2012
    ..Front Edge Technology's proposed high-energy thin-film battery will enable the development of smaller and better hearing devices. ..
  63. 3T MR Scanner for Translational Research using MRI and MRSI
    Sarah J Nelson; Fiscal Year: 2010
    ....
  64. Biofilm Population Structure in the Gangetic Delta
    Gary Schoolnik; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  65. Novel Nitrogen Enriched Air for Fire Suppression
    DONALD STOOKEY; Fiscal Year: 2009
    ..demonstration of the NEA/water mist system, and 4) demonstrated fire extinction while operating in breathable environment. The Phase II program will: 1) quantify the effectiveness of the NEA+mist combination, 2) optimize system, 3) ..
  66. IMMUNOREGULATION OF GUT EPITHELIUM TO ESCAPE PARASITISM
    GILBERT CASTRO; Fiscal Year: 1991
    ..spiralis. Additionally, the project will lead to the development of models for the study of immunopathological and immunophysiological processes in mucosal tissues down to the subcellular level...
  67. Ecosystem disturbance and multiscale transmission of a zoonotic wildlife pathogen
    Philip Craig; Fiscal Year: 2007
    ....
  68. PERIPLASMIC FLAGELLA OF TREPONEMA DENTICOLA
    John Ruby; Fiscal Year: 1993
    ..Regions of homology will define conserved sequences among the spirochetes. These regions are likely to be necessary for PF structure and motility...
  69. SPECIFIC PATHOGEN FREE MACAQUE BREEDING PROGRAM
    M Izard; Fiscal Year: 1999
    ....
  70. Health, Pollution & Economic Development in South Durban
    Stuart Batterman; Fiscal Year: 2004
    ..organizations, to evaluate their perceptions and knowledge regarding impacts and linkages between environment, development, health and socio-economic impacts...
  71. LUNG DRUG DELIVERY WITH CARBON DIOXIDE AEROSOL INHALERS
    Brian Hansen; Fiscal Year: 2009
    ..major changes today due to the phase-out of the use of chlorofluorocarbon propellants (because they harm the environment by damaging the protective ozone layer in the stratosphere);the most popular replacement MDI propellant has ..
  72. UAB Framework Program for Global Health
    John Ehiri; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  73. Study of monkeypox virus in rodents
    R Buller; Fiscal Year: 2005
    ..abstract_text> ..
  74. Microbial Mediation of Habitat Selection and Production
    Edward Walker; Fiscal Year: 2006
    ..Microbial basis for larval habitat production will be studied with field and lab experiments where nutrient sources and microbial communities are quantified, manipulated and larval growth responses and adult production quantified. ..