vascular patency

Summary

Summary: The degree to which BLOOD VESSELS are not blocked or obstructed.

Top Publications

  1. ncbi Balloon angioplasty versus stenting with nitinol stents in intermediate length superficial femoral artery lesions
    Petra Dick
    Department of Angiology, Medical University Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria, Europe
    Catheter Cardiovasc Interv 74:1090-5. 2009
  2. ncbi Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study
    Steven Goldman
    Southern Arizona VA Health Care System and the University of Arizona Sarver Heart Center, Tucson, Arizona, USA
    J Am Coll Cardiol 44:2149-56. 2004
  3. ncbi Association of low serum fetuin A levels with poor arteriovenous access patency in patients undergoing maintenance hemodialysis
    Hung Yuan Chen
    Division of Nephrology, Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan
    Am J Kidney Dis 56:720-7. 2010
  4. ncbi Vascular smooth muscle enhances functionality of tissue-engineered blood vessels in vivo
    Lucas P Neff
    Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    J Vasc Surg 53:426-34. 2011
  5. ncbi Total arterial coronary revascularization: techniques and results in 3,220 patients
    J Tatoulis
    Department of Cardiac Surgery, Royal Melbourne Hospital, Richmond, Australia
    Ann Thorac Surg 68:2093-9. 1999
  6. pmc Hemodialysis arteriovenous fistula patency revisited: results of a prospective, multicenter initiative
    Henricus J T Huijbregts
    University Medical Center Utrecht, Department of Nephrology, 3508 GA Utrecht, The Netherlands
    Clin J Am Soc Nephrol 3:714-9. 2008
  7. ncbi In situ tissue regeneration using a novel tissue-engineered, small-caliber vascular graft without cell seeding
    Takenori Yokota
    Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    J Thorac Cardiovasc Surg 136:900-7. 2008
  8. ncbi Long-term outcomes and risk stratification of patency following nitinol stenting in the femoropopliteal segment: retrospective multicenter analysis
    Osamu Iida
    Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Hyogo, Japan
    J Endovasc Ther 18:753-61. 2011
  9. ncbi Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial
    Steven Goldman
    Cardiology Section 1 111C, Southern Arizona VA Health Care System, 3601 S Sixth Ave, Tucson, AZ 85723, USA
    JAMA 305:167-74. 2011
  10. ncbi Implantation of decellularized small-caliber vascular xenografts with and without surface heparin treatment
    Xue Ning Wang
    Department of Cardiothoracic Surgery, Renji Hospital, Shanghai Jiaotong University Medical College, Shanghai, China
    Artif Organs 31:99-104. 2007

Detail Information

Publications279 found, 100 shown here

  1. ncbi Balloon angioplasty versus stenting with nitinol stents in intermediate length superficial femoral artery lesions
    Petra Dick
    Department of Angiology, Medical University Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria, Europe
    Catheter Cardiovasc Interv 74:1090-5. 2009
    ..We reinvestigated whether primary nitinol stenting is associated with a morphologic and clinical benefit when compared with percutaneous transluminal angioplasty with optional stenting (PTA) in intermediate-length lesions...
  2. ncbi Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative Study
    Steven Goldman
    Southern Arizona VA Health Care System and the University of Arizona Sarver Heart Center, Tucson, Arizona, USA
    J Am Coll Cardiol 44:2149-56. 2004
    ..This study defined long-term patency of saphenous vein grafts (SVG) and internal mammary artery (IMA) grafts...
  3. ncbi Association of low serum fetuin A levels with poor arteriovenous access patency in patients undergoing maintenance hemodialysis
    Hung Yuan Chen
    Division of Nephrology, Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan
    Am J Kidney Dis 56:720-7. 2010
    ..Whether it predicts arteriovenous (AV) access patency is unknown. This study aimed to investigate the association between fetuin A and AV access patency in HD patients...
  4. ncbi Vascular smooth muscle enhances functionality of tissue-engineered blood vessels in vivo
    Lucas P Neff
    Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    J Vasc Surg 53:426-34. 2011
    ..As such, the goal of the present study was to evaluate the effect of SMC coseeding with ECs on TEBV maturation, structure, and function after prolonged in vivo maturation...
  5. ncbi Total arterial coronary revascularization: techniques and results in 3,220 patients
    J Tatoulis
    Department of Cardiac Surgery, Royal Melbourne Hospital, Richmond, Australia
    Ann Thorac Surg 68:2093-9. 1999
    ..We evaluated our experience with this strategy to establish its safety and efficacy...
  6. pmc Hemodialysis arteriovenous fistula patency revisited: results of a prospective, multicenter initiative
    Henricus J T Huijbregts
    University Medical Center Utrecht, Department of Nephrology, 3508 GA Utrecht, The Netherlands
    Clin J Am Soc Nephrol 3:714-9. 2008
    ..This prospective, multicenter study used standardized definitions to analyze patency rates and potential risk factors that affect functional patency and late arteriovenous fistula functionality...
  7. ncbi In situ tissue regeneration using a novel tissue-engineered, small-caliber vascular graft without cell seeding
    Takenori Yokota
    Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    J Thorac Cardiovasc Surg 136:900-7. 2008
    ..In this study, we investigated in situ tissue regeneration in small-diameter arteries using a novel tissue-engineered biodegradable vascular graft that did not require ex vivo cell seeding...
  8. ncbi Long-term outcomes and risk stratification of patency following nitinol stenting in the femoropopliteal segment: retrospective multicenter analysis
    Osamu Iida
    Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Hyogo, Japan
    J Endovasc Ther 18:753-61. 2011
    ..To investigate the long-term outcomes of nitinol stenting in femoropopliteal lesions and to determine the factors associated with restenosis...
  9. ncbi Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial
    Steven Goldman
    Cardiology Section 1 111C, Southern Arizona VA Health Care System, 3601 S Sixth Ave, Tucson, AZ 85723, USA
    JAMA 305:167-74. 2011
    ..The efficacy of the radial artery graft is less clear...
  10. ncbi Implantation of decellularized small-caliber vascular xenografts with and without surface heparin treatment
    Xue Ning Wang
    Department of Cardiothoracic Surgery, Renji Hospital, Shanghai Jiaotong University Medical College, Shanghai, China
    Artif Organs 31:99-104. 2007
    ..Both heparin-treated and non-heparin-treated xenografts seem to undergo a similar cellular remodeling process up to 6 months...
  11. ncbi Percutaneous treatment in iliac artery occlusion: long-term results
    Roberto Gandini
    Departments of Diagnostic Imaging, Interventional Radiology, Molecular Imaging, and Radiotherapy, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy
    Cardiovasc Intervent Radiol 31:1069-76. 2008
    ..In any case, a first-line interventional approach should be considered in elderly patients or in patients with severe comorbidities...
  12. ncbi Long-term outcomes and predictors of iliac angioplasty with selective stenting
    Toshifumi Kudo
    Gonda Goldschmied Vascular Center, University of California at Los Angeles, 90095, USA
    J Vasc Surg 42:466-75. 2005
    ..To review our 11-year experience of iliac angioplasty with selective stenting and to evaluate the safety, short- and long-term patency, clinical success rates, and predictive risk factors in patients with iliac artery occlusive disease...
  13. ncbi Impact of diabetes mellitus on outcomes of superficial femoral artery endoluminal interventions
    Andrew M Bakken
    Center for Vascular Disease, Division of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Vasc Surg 46:946-958; discussion 958. 2007
    ..We examined the consequences of endovascular treatment of the SFA in patients with and without DM...
  14. pmc Antithrombogenic modification of small-diameter microfibrous vascular grafts
    Craig K Hashi
    University of California, San Francisco, CA, USA
    Arterioscler Thromb Vasc Biol 30:1621-7. 2010
    ..To develop small-diameter vascular grafts with a microstructure similar to native matrix fibers and with chemically modified microfibers to prevent thrombosis...
  15. ncbi Primary iliac stenting versus transluminal angioplasty with selective stenting
    Ali F Aburahma
    Department of Surgery, Robert C Byrd Health Sciences Center, West Virginia University, Charleston, WV 25304, USA
    J Vasc Surg 46:965-970. 2007
    ..The preferential use of primary iliac stenting vs selective stenting is controversial. This study compares the early and late clinical outcomes of primary vs selective iliac stenting at our institution...
  16. ncbi Heparin-bonded expanded polytetrafluoroethylene vascular graft for femoropopliteal and femorocrural bypass grafting: 1-year results
    Marc Bosiers
    Department of Vascular Surgery, St Blasius Hospital, Dendermonde, Belgium
    J Vasc Surg 43:313-8; discussion 318-9. 2006
    ..This study assessed the performance of a new heparin-bonded ePTFE vascular graft that was designed to provide resistance to thrombosis and thereby decrease early graft failures and possibly prolong patency...
  17. ncbi Chronic iliac vein occlusion: midterm results of endovascular recanalization
    Tilo Kölbel
    Vascular Center, Malmo University Hospital, Malmo, Sweden
    J Endovasc Ther 16:483-91. 2009
    ..To evaluate patency and clinical outcome in patients treated with endovascular recanalization and stent placement for chronic iliac vein occlusions...
  18. ncbi Sustained suppression of neointimal proliferation by sirolimus-eluting stents: one-year angiographic and intravascular ultrasound follow-up
    J E Sousa
    Institute Dante Pazzanese of Cardiology, Sao Paulo, Brazil
    Circulation 104:2007-11. 2001
    ..The aim of the present investigation was to determine whether these results are sustained over a period of 1 year...
  19. ncbi The radial artery: which place in coronary operation?
    A Parolari
    Department of Cardiac Surgery, University of Milan, Italy
    Ann Thorac Surg 69:1288-94. 2000
    ..The recent report of encouraging 5-year patency rates, supports its continued use as a bypass graft. In this paper, we review the current knowledge about the radial artery as a bypass graft, with special emphasis on the clinical results...
  20. ncbi Improving the clinical patency of prosthetic vascular and coronary bypass grafts: the role of seeding and tissue engineering
    Alexander M Seifalian
    Tissue Engineering Center, University Department of Surgery, Royal Free and University College Medical School, University College London and The Royal Free Hospital, U K
    Artif Organs 26:307-20. 2002
    ..This review encompasses the developments in the two principal technologies used in developing hybrid coronary and peripheral vascular bypass grafts, that is, seeding and tissue engineering...
  21. ncbi External iliac and common iliac artery angioplasty and stenting in men and women
    C H Timaran
    Division of Vascular Surgery, Department of Surgery and Graduate School of Medicine, University of Tennessee Medical Center, Knoxville 37920-6999, USA
    J Vasc Surg 34:440-6. 2001
    ..Conversely, men undergoing EIA stenting have a more favorable outcome than women...
  22. ncbi Meta-analysis of infrapopliteal angioplasty for chronic critical limb ischemia
    Marcello Romiti
    Vascular Surgery Section, Department of Surgery, Health and Medical Sciences Sector, Lusiada Foundation, Santos, Sao Paulo, Brazil
    J Vasc Surg 47:975-981. 2008
    ..This meta-analysis aimed to assess the middle-term outcomes after crural angioplasty in patients with chronic critical limb ischemia and compare results with a meta-analysis of popliteal-to-distal vein bypass graft...
  23. ncbi Angioplasty and stent placement in chronic occlusion of the superficial femoral artery: technique and results
    R M Conroy
    Department of Radiology, Veterans Administration Medical Center, Long Beach, CA 90822, USA
    J Vasc Interv Radiol 11:1009-20. 2000
    ..To improve the patency rate for angioplasty in chronic occlusion of the superficial femoral artery by deploying stents after angioplasty...
  24. ncbi Radial artery patency and clinical outcomes: five-year interim results of a randomized trial
    Brian F Buxton
    Department of Cardiac Surgery, Austin and Repatriation Medical Centre, Melbourne, Victoria, Australia
    J Thorac Cardiovasc Surg 125:1363-71. 2003
    ....
  25. ncbi Primary patency of long-segment self-expanding nitinol stents in the femoropopliteal arteries
    Schila Sabeti
    Department of Angiology, University of Vienna, Medical School, A 1090 Vienna, Austria
    J Endovasc Ther 12:6-12. 2005
    ..To report a retrospective cohort study of nitinol stent implantation in patients at high risk for restenosis owing to long-segment (> or =10 cm) femoropopliteal disease...
  26. pmc Pericyte-based human tissue engineered vascular grafts
    Wei He
    Department of Surgery, University of Pittsburgh, USA
    Biomaterials 31:8235-44. 2010
    ..These results demonstrate the feasibility of a pericyte-based TEVG and suggest that the pericytes play a role in maintaining patency of the TEVG as an arterial conduit...
  27. ncbi Plasminogen supports tumor growth through a fibrinogen-dependent mechanism linked to vascular patency
    Joseph S Palumbo
    Division of Hematology Oncology, Children s Hospital Research Foundation, and University of Cincinnati College of Medicine, OH 45229, USA
    Blood 102:2819-27. 2003
    ..Furthermore, these studies suggest that one target of plasmin(ogen) relevant to tumor progression in vivo is intravascular fibrin...
  28. ncbi Stents in common iliac vein obstruction with acute ipsilateral deep venous thrombosis: early and late results
    Hyo Sung Kwak
    Department of Radiology, Chonbuk National University Medical School, 634 18 Keumam dong, Chonju 560 182, South Korea
    J Vasc Interv Radiol 16:815-22. 2005
    ..To evaluate, by imaging and clinical follow-up, the effectiveness and long-term results of stent placement in cases of common iliac vein obstruction associated with ipsilateral deep vein thrombosis (DVT)...
  29. ncbi Influence of endoscopic versus traditional saphenectomy on event-free survival: five-year follow-up of a prospective randomized trial
    Keith B Allen
    Department of Cardiothoracic Surgery, St Vincent Hospital and Health Care Center, Indianapolis, Indiana, USA
    Heart Surg Forum 6:E143-5. 2003
    ..Although histologic studies suggest no significant difference in vein quality between these two techniques, long-term follow-up is lacking to address whether graft patency and event-free survival are influenced by the harvest method...
  30. ncbi Monthly access flow monitoring with increased prophylactic angioplasty did not improve fistula patency
    Hassan Shahin
    Department of Medicine, Veterans Administration Medical Center and University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242, USA
    Kidney Int 68:2352-61. 2005
    ..Regular access monitoring is recommended to detect and treat access stenosis in order to prevent access thrombosis and failure...
  31. ncbi Activation of nuclear factor-kappa B significantly contributes to lumen loss in a rabbit iliac artery balloon angioplasty model
    J M Breuss
    Department of Vascular Biology and Thrombosis Research, University of Vienna, Austria
    Circulation 105:633-8. 2002
    ....
  32. ncbi Collagen- versus gelatine-coated Dacron versus stretch PTFE bifurcation grafts for aortoiliac occlusive disease: long-term results of a prospective, randomized multicenter trial
    Manfred R Prager
    University of Vienna Medical School and the Ludwig Boltzmann Research Institute for Interdisciplinary Vascular Medicine, Vienna, Austria
    Surgery 134:80-5. 2003
    ..In this prospective randomized multicenter trial, knitted gelatine-coated Dacron, knitted collagen-coated Dacron, and stretch polytetrafluoroethylene (PTFE) aortic bifurcation grafts were compared for their long-term results...
  33. ncbi Outcome after autogenous brachial-basilic upper arm transpositions in the post-National Kidney Foundation Dialysis Outcomes Quality Initiative era
    Heather Y Wolford
    Center for Vascular Disease, Division of Vascular Surgery, University of Rochester, NY 14642, USA
    J Vasc Surg 42:951-6. 2005
    ..We reviewed our experience with autogenous brachial-basilic upper arm transpositions (BTX) to clarify current maturation and patency rates and provide realistic expectations for a tertiary referral vascular practice...
  34. ncbi Endovascular interventions for TASC II D femoropopliteal lesions
    Donald T Baril
    Division of Vascular Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Penn 15232, USA
    J Vasc Surg 51:1406-12. 2010
    ..The purpose of this study was to evaluate outcomes of endovascular interventions on TransAtlantic InterSociety (TASC) II D femoropopliteal occlusive disease...
  35. ncbi Reduced primary patency rate in diabetic patients after percutaneous intervention results from more frequent presentation with limb-threatening ischemia
    Brian G Derubertis
    Division of Vascular Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University and Columbia University College of Physicians and Surgeons, 525 E 68th Street, New York, NY 10021, USA
    J Vasc Surg 47:101-8. 2008
    ..This study aimed to assess differential outcomes in between diabetics and nondiabetics in lower extremity percutaneous interventions...
  36. ncbi A new technique for autogenous brachiobasilic upper arm transposition for vascular access for hemodialysis
    W Weyde
    Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland
    J Vasc Access 7:74-6. 2006
    ..In case of late thrombosis, the reparation of such a fistula is almost impossible...
  37. ncbi Excimer laser recanalization of femoropopliteal lesions and 1-year patency: results of the CELLO registry
    Rajesh M Dave
    Harrisburg Hospital, Harrisburg, Pennsylvania 17101, USA
    J Endovasc Ther 16:665-75. 2009
    ..To evaluate the safety and efficacy of a modified laser catheter designed for the endovascular treatment of peripheral artery disease (PAD) affecting the superficial femoral artery (SFA) and proximal popliteal artery...
  38. ncbi Biological mechanisms influencing prosthetic bypass graft patency: possible targets for modern graft design
    D M Scharn
    Department of Vascular Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur J Vasc Endovasc Surg 43:66-72. 2012
    ..The sequence of biochemical events that lead to thrombosis of grafts is used as a guideline to describe possible counteracting prosthetic surface interventions in each separate phase of the process...
  39. ncbi Four-year randomized prospective comparison of percutaneous ePTFE/nitinol self-expanding stent graft versus prosthetic femoral-popliteal bypass in the treatment of superficial femoral artery occlusive disease
    Karen McQuade
    Department of Vascular Surgery, Baylor University Medical Center, Dallas, TX 75226, USA
    J Vasc Surg 52:584-90; discussion 590-1, 591.e1-591.e7. 2010
    ....
  40. ncbi Ultrasound-guided infraclavicular brachial plexus block enhances postoperative blood flow in arteriovenous fistulas
    Levent Sahin
    Department of Anesthesiology, Gaziantep University, Faculty of Medicine, Gaziantep, Turkey
    J Vasc Surg 54:749-53. 2011
    ..We compared the effects of ultrasound-guided, infraclavicular brachial plexus block and local infiltration anesthesia on blood flow in the radial artery and AVF during the early and late postoperative periods...
  41. ncbi Primary stenting of the superficial femoral and popliteal artery
    David D Dearing
    Huntington Hospital, Pasadena, California, USA
    J Vasc Surg 50:542-7. 2009
    ..It is the purpose of this study to determine the efficacy and durability of primary stenting of the superficial femoral and popliteal artery...
  42. ncbi Dialysis fistula or graft: the role for randomized clinical trials
    Michael Allon
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Clin J Am Soc Nephrol 5:2348-54. 2010
    ..Careful clinical judgment should optimize vascular access outcomes and minimize prolonged catheter dependence among hemodialysis patients...
  43. ncbi Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery
    Renato D Lopes
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    N Engl J Med 361:235-44. 2009
    ....
  44. ncbi Regional nerve block allows for optimization of planning in the creation of arteriovenous access for hemodialysis by improving superficial venous dilatation
    I A Laskowski
    Division of Vascular Surgery, New York University School of Medicine, New York, NY 10016, USA
    Ann Vasc Surg 21:730-3. 2007
    ..The routine use of regional anesthesia as well as intraoperative ultrasound during AV access surgery can lead to improved site selection and increased opportunity for AV fistula creation...
  45. ncbi The Zilver® PTX® Single Arm Study: 12-month results from the TASC C/D lesion subgroup
    M Bosiers
    Department of Vascular Surgery, AZ St Blasius, Dendermonde, Belgium
    J Cardiovasc Surg (Torino) 54:115-22. 2013
    ..The aim of the present article was to report the 12-month results of the Zilver® PTX® Single Arm StudyTASC C/D de novo lesion subgroup...
  46. ncbi Randomized flow capacity comparison of skeletonized and pedicled left internal mammary artery
    Vito Mannacio
    Department of Cardiac Surgery, University of Naples Federico II, Naples, Italy
    Ann Thorac Surg 91:24-30. 2011
    ..The preferential harvesting technique of the internal mammary artery has been periodically debated. This randomized study evaluated the flow outcome of the skeletonized versus pedicled left internal mammary artery...
  47. ncbi Durability and cumulative functional patency of transposed and nontransposed arteriovenous fistulas
    Hung Michael Choi
    Department of Surgery, Division of Vascular Surgery, UMDNJ New Jersey Medical School, 185 S Orange Avenue, Newark, NJ 07103 2714, USA
    J Vasc Surg 38:1206-12. 2003
    ..However, the cumulative functional patency and durability of transposed AV fistulas (TAVF) compared with nontransposed AV fistulas (AVF) and prosthetic bridging grafts (AVG) remains ill-defined...
  48. ncbi Basilic vein transposition fistula: a good option for maintaining hemodialysis access site options?
    Rajeev K Rao
    Division of Vascular Surgery, Department of Surgery, University of Southern California, Keck School of Medicine, Los Angeles, California, USA
    J Vasc Surg 39:1043-7. 2004
    ..We review the outcomes of basilic vein transposition (BVT) to assess its value as a primary upper arm arteriovenous access option...
  49. ncbi Heparin-bonded ePTFE grafts compared with vein grafts in femoropopliteal and femorocrural bypasses: 1- and 2-year results
    Kim Daenens
    Department of Vascular Surgery, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
    J Vasc Surg 49:1210-6. 2009
    ..This nonrandomized study compared the performance of these grafts with that of ASV conduits in the largest clinical series of heparin-bonded ePTFE graft implantations reported so far...
  50. ncbi Arteriovenous fistula formation using transposed basilic vein: extensive single centre experience
    S J F Harper
    Department of Infection, Immunity and Inflammation, Transplantation Division, University of Leicester, Leicester, UK
    Eur J Vasc Endovasc Surg 36:237-41. 2008
    ..The expanding haemodialysis population has lead to increased requirement for more complex vascular access. The aim of this study is to present the results of an extensive series of brachiobasilic arteriovenous fistulae...
  51. ncbi Heparin-bonded Dacron or polytetrafluorethylene for femoropopliteal bypass: five-year results of a prospective randomized multicenter clinical trial
    Carol Devine
    Department of Surgery, Wythenshawe Hospital, Manchester M23 9LT, England
    J Vasc Surg 40:924-31. 2004
    ..Despite the range of potential prosthetics, polytetrafluoroethylne (PTFE) clearly predominates in current femoropopliteal practice. We compared heparin-bonded Dacron (HBD) with PTFE in a randomized multicenter clinical trial...
  52. pmc The in vivo performance of small-caliber nanofibrous polyurethane vascular grafts
    Zuo Jun Hu
    Department of Vascular Surgery, the First Affiliated Hospital of Sun Yat Sen University, NO, 58 Zhongshan 2nd Road, Guangzhou, 510080, China
    BMC Cardiovasc Disord 12:115. 2012
    ..In the present study, we examined the in vivo biocompatibility and stability of these grafts...
  53. pmc Risk factors associated with patency loss of hemodialysis vascular access within 6 months
    Mauricio Monroy-Cuadros
    Division of Transplantation, Department of Surgery, Faculty of Medicine, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada
    Clin J Am Soc Nephrol 5:1787-92. 2010
    ....
  54. ncbi Intensive statin therapy: a favorable adjunct to the improvement of small-diameter vascular grafts
    - Jie Li
    Department of Vascular Surgery, First Affiliated Hospital, Sun Yat Sen University, Guangzhou, China
    Angiology 61:427-36. 2010
    ..In conclusion, intensive statin therapy could be considered a favorable option to improve small-diameter vascular graft patency...
  55. ncbi Improved noninvasive assessment of coronary artery bypass grafts with 64-slice computed tomographic angiography in an unselected patient population
    Tanja S Meyer
    Institut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum Munchen, Klinik an der TU München, Munich, Germany
    J Am Coll Cardiol 49:946-50. 2007
    ....
  56. ncbi Recommended standards for reports dealing with arteriovenous hemodialysis accesses
    Anton N Sidawy
    Committee on Reporting Standards for Arterio Venous Accesses of The Society for Vascular Surgery and the American Association for Vascular Surgery, Washington, DC, USA
    J Vasc Surg 35:603-10. 2002
    ....
  57. ncbi Dacron or PTFE for above-knee femoropopliteal bypass. a multicenter randomised study
    L P Jensen
    Department of Vascular Surgery B, Copenhagen University Gentofte Hospital, Copenhagen, Denmark
    Eur J Vasc Endovasc Surg 34:44-9. 2007
    ..To compare polytetrafluorethylene (PTFE) and polyester grafts (Dacron) for above knee femoropopliteal bypass...
  58. ncbi Timing of the restenosis following nitinol stenting in the superficial femoral artery and the factors associated with early and late restenoses
    Osamu Iida
    Kansai Rosai Hospital Cardiovascular Center, 3 1 69 Inabaso, Amagasaki, Hyogo 660 8511, Japan
    Catheter Cardiovasc Interv 78:611-7. 2011
    ..We sought to investigate the timing of restenosis and the restenosis factors following nitinol stenting in the superficial femoral artery (SFA)...
  59. ncbi Computational fluid dynamics and vascular access
    Ulf Krueger
    Deparment of Vascular Surgery, Queen Elisabeth Hospital, Berlin, Germany
    Artif Organs 26:571-5. 2002
    ..The anastomotic wall shear stress is decreased. The results of this study strongly support patch form use to reduce the incidence of intimal hyperplasia and venous anastomotic stenoses...
  60. ncbi Multislice spiral computed tomography for the detection of coronary stent restenosis and patency
    Stefan Kruger
    Medical Clinic I, University Hospital, University of Technology, Aachen, Germany
    Int J Cardiol 89:167-72. 2003
    ..We determined the value of MSCT to non-invasively detect significant in-stent restenosis after coronary artery stenting...
  61. ncbi Endovascular revascularization of chronically thrombosed arteriovenous fistulas and grafts for hemodialysis: a retrospective study in 15 patients with 18 access sites
    Mei Jui Weng
    Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    Cardiovasc Intervent Radiol 34:319-30. 2011
    ....
  62. ncbi Comparing vein with collagen impregnated woven polyester prosthesis in above-knee femoropopliteal bypass grafting
    A Mohammadi Tofigh
    Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Int J Surg 5:109-13. 2007
    ..A prospectively randomized clinical trial was designed to evaluate the effectiveness of reversed saphenous vein in comparison with that of collagen impregnated woven polyester prosthesis in above-knee arterial reconstruction...
  63. ncbi Different vascular smooth muscle cell apoptosis in the human internal mammary artery and the saphenous vein. Implications for bypass graft disease
    Karin Frischknecht
    Cardiovascular Research, Physiology Institute, University of Zurich, Zurich, Switzerland
    J Vasc Res 43:338-46. 2006
    ..We examined whether proliferation and apoptosis of vascular smooth muscle cells (VSMC) from human coronary artery bypass vessels differ according to patency rates...
  64. ncbi Effect of laser perforation on the remodeling of acellular matrix grafts
    Helga Bergmeister
    Institute of Biomedical Research, Medical University of Vienna, Austria
    J Biomed Mater Res B Appl Biomater 74:495-503. 2005
    ..These results suggest that the increased matrix porosity induced by laser perforation promotes graft remodeling and reconstitution with host cells...
  65. ncbi Development of anti-atherosclerotic tissue-engineered blood vessel by A20-regulated endothelial progenitor cells seeding decellularized vascular matrix
    Chuhong Zhu
    Department of Anatomy, Key Lab for Biomechanics of Chongqing, Third Military Medical University, Gao Tan Yan Street, Shaping Ba District, Chongqing 400038, China
    Biomaterials 29:2628-36. 2008
    ..These results demonstrate that transgenic tissue-engineered blood vessels have long-term patency and unique anti-stenotic properties...
  66. pmc Dacron vs. PTFE as bypass materials in peripheral vascular surgery--systematic review and meta-analysis
    Stephanie Roll
    Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
    BMC Surg 8:22. 2008
    ..Thus, the aim of this meta-analysis and systematic review was to compare the effectiveness of these two prosthetic bypass materials (Dacron and PTFE)...
  67. ncbi Angiographic evaluation of carotid artery grafting with prefabricated small-diameter, small-intestinal submucosa grafts in sheep
    Dusan Pavcnik
    Dotter Interventional Institute, Oregon Health Sciences University, Portland, OR 97201, USA
    Cardiovasc Intervent Radiol 32:106-13. 2009
    ..The complications found were partially related to the graft construction from four SIS layers. Detailed longitudinal angiographic study should become an essential part of any future evaluation of small-vessel SIS grafting...
  68. ncbi Reperfusion arrhythmias: are they only a marker of epicardial reperfusion or continuing myocardial ischemia after acute myocardial infarction?
    Gulumser Heper
    Department of Cardiology, SSK Ihtisas Hospital, Etlik
    Angiology 58:663-70. 2007
    ..This finding suggests that the continuing myocardial ischemia represented by TIMI flow at the coronary angiography after acute myocardial infarction may have an important role in the pathogenesis of reperfusion arrhythmias...
  69. ncbi Decellularized, xenogeneic small-diameter arteries: transition from a muscular to an elastic phenotype in vivo
    Helga Bergmeister
    Division of Biomedical Research, Medical University of Vienna, Vienna, Austria
    J Biomed Mater Res B Appl Biomater 87:95-104. 2008
    ..After 6 months elastin biosynthesis and complete graft remodeling toward an elastic vessel was evident. These results indicate that temporary inflammation does not interfere with long-term vascular remodeling...
  70. ncbi Endovascular management of acute extensive iliofemoral deep venous thrombosis caused by May-Thurner syndrome
    N H Patel
    Department of Radiology, Indiana University Medical Center, Indianapolis, USA
    J Vasc Interv Radiol 11:1297-302. 2000
    ..The authors report their experience on the treatment of acute extensive iliofemoral deep venous thrombosis (DVT) due to May-Thurner syndrome using endovascular techniques...
  71. pmc Percutaneous intervention in axillary loop-configured arteriovenous grafts for chronic hemodialysis patients
    Beom Jin Park
    Department of Radiology, College of Medicine, Korea University, Seoul 136 705, Korea
    Korean J Radiol 11:195-202. 2010
    ..The purpose of this study was to evaluate the fistulographic features of malfunctioning axillary loop-configured arteriovenous grafts and the efficacy of percutaneous interventions in failed axillary loop-configured arteriovenous grafts...
  72. ncbi Experimental study of hemodynamics in procedures to treat access-related ischemia
    Juergen Zanow
    Department of General and Vascular Surgery, Friedrich Schiller University, Jena, Germany
    J Vasc Surg 48:1559-65. 2008
    ..This experimental study investigated the hemodynamic effect of corrective procedures for arteriovenous access-related ischemia in pulsatile flow...
  73. ncbi Selective stenting in subintimal angioplasty: analysis of primary stent outcomes
    Gregory C Schmieder
    Division of Vascular Surgery, Eastern Virginia Medical School, Norfolk, VA 23507, USA
    J Vasc Surg 48:1175-80; discussion 1180-1. 2008
    ..The role of stents in SIA is currently unknown. We performed a retrospective review of selective stent use in SIA to assess outcomes and factors affecting these results...
  74. ncbi Contrast-enhanced magnetic resonance angiography findings prior to hemodialysis vascular access creation: a prospective analysis
    R N Planken
    Department of Vascular Surgery, Maastricht University Hospital, Maastricht University Medical School, Maastricht, The Netherlands
    J Vasc Access 9:269-77. 2008
    ..To determine prospectively the clinical value of contrast-enhanced magnetic resonance angiography (CE-MRA) for assessment of the arterial inflow and venous outflow prior to vascular access (VA) creation...
  75. ncbi The TransAtlantic InterSociety Consensus (TASC) classification system in iliac arterial stent placement: long-term patency and clinical limitations
    Kwang Bo Park
    Department of Radiology and the Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, Irwon dong, Gangnam Gu, Seoul, 135 710, Korea
    J Vasc Interv Radiol 18:193-201. 2007
    ..To evaluate the long-term patency of iliac arterial stent placement according to individual TransAtlantic Intersociety Consensus (TASC) stages and demonstrate the limitations of TASC classification for iliac arterial disease...
  76. pmc AMS INSIGHT--absorbable metal stent implantation for treatment of below-the-knee critical limb ischemia: 6-month analysis
    Marc Bosiers
    Department of Vascular Surgery, AZ St Blasius, Kroonveldlaan 50, 9200, Dendermonde, Belgium
    Cardiovasc Intervent Radiol 32:424-35. 2009
    ..0%). Although the present study indicates that the AMS technology can be safely applied, it did not demonstrate efficacy in long-term patency over standard PTA in the infrapopliteal vessels...
  77. ncbi Thrombosed dialysis access grafts: randomized comparison of the Amplatz thrombectomy device and surgical thromboembolectomy
    Renan Uflacker
    Division of Vascular and Interventional Radiology, Department of Radiology, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC 29425 9737, USA
    Eur Radiol 14:2009-14. 2004
    ..The results of the performance of both methods were comparable. No statistically significant differences were seen...
  78. ncbi Flow reduction in high-flow arteriovenous access using intraoperative flow monitoring
    Juergen Zanow
    Department of Vascular Surgery, Queen Elisabeth Hospital, Berlin, Germany
    J Vasc Surg 44:1273-8. 2006
    ..This study used intraoperative monitoring of the access flow to evaluate the results of flow reduction in the management of high-flow arteriovenous access-related symptoms of distal ischemia and cardiac insufficiency...
  79. ncbi Subintimal placement of covered stent versus subintimal balloon angioplasty in the treatment of long-segment superficial femoral artery occlusion
    Panagiotis Kougias
    Division of Vascular Surgery and Endovascular Therapy, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston VAMC, Houston TX 77030, USA
    Am J Surg 198:645-9. 2009
    ..The relative effectiveness of subintimal placement of a covered stent (CS) versus balloon-only subintimal angioplasty (SIA) remains uncertain...
  80. ncbi Endovascular management of the popliteal artery: comparison of atherectomy and angioplasty
    Elie Semaan
    Section of Vascular and Endovascular Surgery, Boston University School of Medicine, Boston, MA 02118, USA
    Vasc Endovascular Surg 44:25-31. 2010
    ..We evaluated the technical success, complications, and midterm outcomes of atherectomy and angioplasty involving the popliteal segment...
  81. ncbi Percutaneous rheolytic thrombectomy for thrombosed autogenous fistulae and prosthetic arteriovenous grafts: outcome after aggressive surveillance and endovascular management
    Stavros K Kakkos
    Division of Vascular Surgery, Department of Surgery, Henry Ford Hospital, 2799 W Grand Boulevard, Detroit, MI 48202, USA
    J Endovasc Ther 15:91-102. 2008
    ..To study the outcome of rheolytic thrombectomy for hemodialysis access occlusion...
  82. ncbi Prospective, randomized single-center trial to compare cryoplasty versus conventional angioplasty in the popliteal artery: midterm results of the COLD study
    Thomas Jahnke
    Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel, Germany
    J Vasc Interv Radiol 21:186-94. 2010
    ..To evaluate safety and efficacy of cryoplasty versus conventional angioplasty for focal popliteal arterial occlusive disease...
  83. ncbi Role of superficial femoral artery stents in the management of arterial occlusive disease: review of current evidence
    Stephen Perrio
    St George s Vascular Institute, London, UK
    Vascular 18:82-92. 2010
    ..However, the studies used displayed a high degree of heterogeneity, and some used stent technology that is now considered obsolete. Ongoing randomized controlled trials will provide a more definitive answer to this important problem...
  84. ncbi Equivalent secondary patency rates of upper extremity Vectra Vascular Access Grafts and transposed brachial-basilic fistulas with aggressive access surveillance and endovascular treatment
    Stavros K Kakkos
    Division of Vascular Surgery, Department of Surgery, Henry Ford Hospital, Detroit, MI 48202, USA
    J Vasc Surg 47:407-14. 2008
    ..AV grafts are in general least preferred; however, there is very limited data comparing directly the last two modalities. The aim of the present study is to compare outcomes of the TBB fistula and the Vectra Vascular Access Graft...
  85. ncbi Drug eluting balloons
    Nicolas A Diehm
    Division of Clinical and Interventional Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, Bern, Switzerland
    Tech Vasc Interv Radiol 13:59-63. 2010
    ..The purpose of this article is to review the clinical utility of drug-eluting balloons for lower limb endovascular interventions...
  86. ncbi Native arteriovenous fistula: preoperative evaluation
    Marko Malovrh
    Department of Nephrology, University Medical Center Ljubljana, Ljubljana, Slovenia
    Am J Kidney Dis 39:1218-25. 2002
    ....
  87. ncbi Results of aggressive graft surveillance and endovascular treatment on secondary patency rates of Vectra Vascular Access Grafts
    Stavros K Kakkos
    Division of Vascular Surgery, Henry Ford Hospital, Detroit, Mich, USA
    J Vasc Surg 45:974-80. 2007
    ....
  88. ncbi Comparison of cutting balloon versus high-pressure balloon angioplasty for resistant venous stenoses of native hemodialysis fistulas
    Chih Cheng Wu
    Department of Medicine, Hsinchu General Hospital, No 25, Ln 442, Sec 1, Jingguo Rd, Hsinchu City 300, Taiwan
    J Vasc Interv Radiol 19:877-83. 2008
    ..To compare the technical success, safety, and patency of cutting balloon angioplasty versus high-pressure balloon angioplasty in the treatment of resistant native hemodialysis fistula stenoses...
  89. ncbi Cutting balloon angioplasty for resistant venous stenoses of dialysis access: immediate and patency results
    Chih Cheng Wu
    Department of Medicine, Hsinchu General Hospital and School of Medicine, Yang Ming University, Taipei, Taiwan
    Catheter Cardiovasc Interv 71:250-4. 2008
    ..To evaluate the technical success, safety and patency of cutting balloon angioplasty for the treatment of resistant dialysis access stenoses...
  90. ncbi Endovascular treatment of infra-popliteal arteries in patients with critical limb ischemia
    A Lejay
    Department of Vascular Surgery, University Hospital of Strasbourg, France
    Acta Chir Belg 109:684-93. 2009
    ..Despite the non entirely satisfactory patency rates, endovascular treatment may provide wound healing and limb salvage...
  91. ncbi Patency of splenic vessels after laparoscopic spleen and splenic vessel-preserving distal pancreatectomy
    Y S Yoon
    Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Bundang gu, Gyeonggi Do, Korea
    Br J Surg 96:633-40. 2009
    ..This study evaluated the short- and long-term patency of preserved splenic vessels after laparoscopic spleen-preserving distal pancreatectomy (SPDP) with preservation of the splenic vessels...
  92. ncbi Performance goals and endpoint assessments for clinical trials of femoropopliteal bare nitinol stents in patients with symptomatic peripheral arterial disease
    Krishna J Rocha-Singh
    Prairie Vascular Institute, Springfield, Illinois 62794 9420, USA
    Catheter Cardiovasc Interv 69:910-9. 2007
    ..This analysis proposes safety and performance goals for prospective single-arm trials of bare nitinol stents to treat patients with debilitating claudication associated with femoropopliteal (FP) atherosclerotic lesions...
  93. ncbi Percutaneous angioplasty and stenting of the superficial femoral artery
    Scott M Surowiec
    Center for Vascular Disease, Division of Vascular Surgery, Department of Surgery, University of Rochester, NY 14642, USA
    J Vasc Surg 41:269-78. 2005
    ....
  94. ncbi Primary patency rates of AV fistulas and the effect of patient variables
    M Field
    The Vascular Unit, University Hospital of North Staffordshire NHS Trust, UK
    J Vasc Access 9:45-50. 2008
    ..In addition, an attempt has been made to address the main issue of survival rates in this high risk patient population...
  95. ncbi Ultrasound-enhanced Thrombolysis
    Amir Motarjeme
    Midwest Vascular Institute of Illinois, Downers Grove, Illinois 60515, USA
    J Endovasc Ther 14:251-6. 2007
    ..To report a single-center clinical experience with ultrasound-enhanced thrombolysis in the treatment of both arterial and venous thromboses...
  96. ncbi Restoration of patency in iliofemoral deep vein thrombosis with catheter-directed thrombolysis does not always prevent post-thrombotic damage
    Y J Park
    Department of Surgery, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 744, Republic of Korea
    Eur J Vasc Endovasc Surg 36:725-30. 2008
    ..To evaluate the long-term results of catheter-directed thrombolysis (CDT) and the feasibility of stent placement for lower extremity deep vein thrombosis (DVT)...
  97. ncbi Catheter-directed thrombolysis with percutaneous rheolytic thrombectomy versus thrombolysis alone in upper and lower extremity deep vein thrombosis
    Hyun S Kim
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Cardiovasc Intervent Radiol 29:1003-7. 2006
    ..To compare the efficacy of catheter-directed thrombolysis (CDT) alone versus CDT with rheolytic percutaneous mechanical thrombectomy (PMT) for upper and lower extremity deep vein thrombosis (DVT)...
  98. ncbi Treatment of critical limb ischemia using ultrasound-enhanced thrombolysis (PARES Trial): final results
    Christian Wissgott
    Department of Radiology, DRK Kliniken Mark Brandenburg, Berlin, Germany
    J Endovasc Ther 14:438-43. 2007
    ..To evaluate the safety and performance of ultrasound-enhanced thrombolysis in the treatment of acute thrombotic or embolic occlusion of the lower limb arteries...
  99. ncbi SMART stent for salvage of hemodialysis access grafts
    Patrick Michael Vogel
    Sutter Institute for Medical Research, Sutter Hospital, Sacramento, California, USA
    J Vasc Interv Radiol 15:1051-60. 2004
    ..To evaluate the SMART stent for treating angioplasty-resistant hemodialysis access venous stenoses...
  100. ncbi Nitinol stents in hemodialysis access
    Timothy W I Clark
    Section of Vascular and Interventional Radiology, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA
    J Vasc Interv Radiol 15:1037-40. 2004
  101. ncbi Primary nitinol stenting for femoropopliteal disease
    Mark W Mewissen
    Vascular Center, St Luke s Medical Center, 2801 W Kinnickinnic River Parkway, Suite 514, Milwaukee, WI 53215, USA
    J Endovasc Ther 16:II63-81. 2009
    ..Development and implementation of uniform reporting and surveillance standards is important for optimizing current and future research...

Research Grants62

  1. Treatment of stroke with a clinically approved proteasome inhibitor
    Li Zhang; Fiscal Year: 2012
    ..and tPA on cerebral infarction, neurological function, thrombolysis, microvascular thrombus formation, vascular patency and integrity in aged rats after embolic stroke...
  2. Role of Maternal Platelets in the Placenta and Pregnancy Complications
    Rashmi Sood; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Vascular patency and adequate blood flow are essential components of normal placental function...
  3. Carbon monoxide mediated inhibition of intimal hyperplasia
    Edith Tzeng; Fiscal Year: 2013
    ..The potential benefit of these studies to the health care of veterans is great by prolonging vascular patency after revascularization and increase functional status and limb preservation...
  4. Mechanism of thrombolytic tPA induced intracerebral hemorrhage after stroke
    Daniel A Lawrence; Fiscal Year: 2013
    ..Ideal treatment for ischemic stroke would simultaneously promote the reestablishment of vascular patency, inhibit the development of cerebral edema, and reduce the incidence of hemorrhagic transformation...
  5. PLATELETS, PLATELET AGGREGATES & PLASMINOGEN ACTIVATION
    Joseph Loscalzo; Fiscal Year: 1991
    ..and very likely important protective mechanism afforded by tissue plasminogen activator in the maintenance of vascular patency. From these studies, we hope to gain insight into mechanisms by which vessel wall products facilitate ..
  6. Interventional Management of Stroke Study (IMS III)
    JOSEPH PAUL BRODERICK; Fiscal Year: 2012
    ..to treatment as determined by an NIHSSS of 0-2 at 24 hours;(3) a CT angiography assessment of intracranial vascular patency at 24 hours;(4) the volume of infarction on 24-hour CT;(5) the rate of reperfusion (TICI Grade II or III ..
  7. STRUCTURES OF COAGULATION COFACTORS
    STEPHEN EVERSE; Fiscal Year: 2003
    he coagulation arm of hemostasis (the maintenance of vascular patency) is triggered in response to various stimuli and results in the explosive generation of thrombin...
  8. A NOVEL APPROACH TO TARGET INFLAMMATION AND THROMBOSIS
    Harshal Nandurkar; Fiscal Year: 2007
    ..Inhibition of this interaction helps to maintain vascular patency. CD39/NTPase-1 is a key enzyme expressed on endothelial cells and platelets, which inhibits platelet ..
  9. Treatment of Acute Embolic Stroke with Statins and rt-PA
    Zheng Gang Zhang; Fiscal Year: 2009
    ..LSCM) techniques, we will first investigate the effects of short-term, high-dose atorvastatin on cerebral vascular patency and integrity including cerebral blood flow (CBF) and BBB leakage, and the neurotoxic effects of tPA...
  10. EXAMINATION OF PERFUSION OF THE HEART BY 19F NMR
    Craig Malloy; Fiscal Year: 1990
    ..include the determination of the potentials of fluorocarbons in (a) aiding in the clinical management of ischemic heart disease and (b) as agents for NMR imaging for assessment of infarct size, vascular patency, and myocardial perfusion.
  11. ANTITUMOR ACTIVITY OF RECOMBINANT INTERLEUKIN I
    Paul Braunschweiger; Fiscal Year: 1991
    ..Time and dose response studies will be conducted to determine the effects of IL-1 on blood flow, vascular patency tumor pH and water distribution in tumor and normal tissues by isotope dilution methods...
  12. NOVEL INHIBITORS OF BRAIN ISCHEMIA
    MICHAEL VITEK; Fiscal Year: 2003
    ..pathway, while maintaining the extrinsic coagulation mechanisms, might be efficacious in restoring vascular patency while preventing increased risk for intracerebral hemorrhage...
  13. Homocysteine/Hypertension & Vascular Lesion Formation
    Peter Lin; Fiscal Year: 2008
    ..abstract_text> ..
  14. Mechanisms of Shear-Regulated Vein Graft Remodeling
    Scott Berceli; Fiscal Year: 2008
    ..Insight into these signaling pathways, in combination with development of these powerful gene inhibition techniques, offers the potential for direct application to the clinical setting. ..
  15. Thrombus resolution is CXC chemokine dependent
    Peter Henke; Fiscal Year: 2006
    ..abstract_text> ..
  16. Clinical Research Using Non-Fourier 3D Cardiac MRI
    Frank Rybicki; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  17. GENETIC ENGINEERING OF A FAILURE RESISTANT VEIN GRAFT
    Michael Conte; Fiscal Year: 2003
    ..The long term objective is to develop a safe, efficient, and effective protocol for intraoperative gene therapy that will engineer vein bypass grafts that are resistant to occlusion. ..
  18. Vein wall remodeling after DVT is matrix metalloproteinase dependent
    Peter Henke; Fiscal Year: 2009
    ..This proposal will provide important mechanistic insight into the pathophysiology of post-phelbitic syndrome with real potential translation to decreasing the morbidity from this under-acknowledged disease. ..
  19. Genetic Predictors of Outcome in Acute MI
    Marc Sabatine; Fiscal Year: 2005
    ..Genomic control will be employed to detect and control for population stratification. Interaction terms will be incorporated into regression models to explore gene-environment and pharmacogenomic interactions. ..
  20. Reducing Risk Factors in Peripheral Arterial Disease
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ....
  21. 3D SONOELASTOGRAPHY IMAGING FOR PROSTATE CANCER
    Deborah Rubens; Fiscal Year: 2006
    ..Year 1: 25 patients) Aim 3: Apply the results of aims 1 and 2 to evaluate the clinical utility of in-vivo prostate cancer detection by sonoelastography. (Years 2-4: 90 patients) ..
  22. 3D Prostate Cancer Imaging Based on "Crawling Wave" Excitation
    Deborah J Rubens; Fiscal Year: 2010
    ..Successful development of the novel 3D crawling wave imaging technology will be readily applicable to ultrasound scanners and therefore can be widely disseminated. ..
  23. HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
    Michael Allon; Fiscal Year: 2007
    ..The primary endpoint will be fistula thrombosis within 6 weeks, and the secondary endpoint will be the ability to use the fistula successfully for dialysis within 6 months. ..
  24. Measuring the Efficacy of Endovascular Treatment of AAA
    Peter Faries; Fiscal Year: 2007
    ..abstract_text> ..
  25. Inflammation and Peripheral Arterial Disease Outcomes
    Mary McDermott; Fiscal Year: 2008
    ..Results will be used to develop interventions to improve functioning and prevent functional decline in PAD. ..
  26. Percutaneous MR Guided Creation of a Meso-Caval Shunt
    Aravind Arepally; Fiscal Year: 2008
    ....
  27. Mechanisms of Ductus Arteriosus Regulation
    JOHN JEFFREY REESE; Fiscal Year: 2010
    ..These studies will examine new roles for prostaglandins and their relationship with other vasoactive mediators during development. ..
  28. Pathophysiologies Involving Hemostasis-related Genes
    Francis Castellino; Fiscal Year: 2008
    ..abstract_text> ..
  29. Osteoprotegerin and osteopontin in aortic aneurysm
    Jonathan Golledge; Fiscal Year: 2009
    ..Understanding the role of these calcium-controlling proteins in artery weakness and how drug therapy can interfere in these effects is an important step in the development of new treatment for aortic aneurysm. ..
  30. Prospective Investigation for Pulmonary Embolism Dx III
    Paul Stein; Fiscal Year: 2008
    ..abstract_text> ..
  31. uPA RECEPTOR SIGNALING AND CELL MIGRATION
    Mark Davies; Fiscal Year: 2005
    ..It is anticipated that data generated from these studies will provide valuable insights for the development of therapeutic intervention to address clinical relevant problems of vessel restenosis. (End of Abstract) ..
  32. ULTRASONIC TISSUE CHARACTERIZATION OF CARDIAC REMODELING
    Samuel Wickline; Fiscal Year: 2004
    ....
  33. Biologic Ventricular Assist Device
    Robert Kloner; Fiscal Year: 2004
    ..Identification and characterization of transplants will be carried out with PCR analysis of the Y chromosome (male cells into female host), detailed histologic analysis and immunostaining for muscle cell markers. ..
  34. QUANTIFICATION OF FACTORS LEADING TO VEIN GRAFT FAILURE
    Daniel Leotta; Fiscal Year: 2004
    ..By developing methods to detect the early indicators of impending failure, this project offers the opportunity to extend the useful life of the grafts by permitting early treatment of the lesions. ..
  35. ALCOHOL, ACETAMINOPHEN, AND LIVER SINUSOID DYSFUNCTION
    ROBERT MC CUSKEY; Fiscal Year: 2004
    ..A better knowledge of the hepatic pathophysiology of alcohol bringing also should result. ..
  36. Transportable Chlorine Dioxide Sterilization System
    Stuart Williams; Fiscal Year: 2004
    ..Following completion of these studies Phase II funding will be sought to optimize and commercialize a transportable sterilization unit. ..
  37. BLOOD FACTORS AND PERIPHERAL ARTERIAL DISEASE OUTCOMES
    Mary McDermott; Fiscal Year: 2004
    ....
  38. PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-II
    Paul Stein; Fiscal Year: 2003
    ..4) The team of investigators is strong, and has collaborated previously in successful research in PE. ..
  39. EARLY DIAGNOSIS AND TREATMENT OF DIALYSIS GRAFT STENOSIS
    Michelle Robbin; Fiscal Year: 2003
    ..Access patency will be followed for at least 2 years, or until placement of a new access. All other aspects of the patients' medical and dialysis care will follow usual medical standards. ..
  40. PERIPHERAL ARTERIAL DISEASE AND FUNCTIONAL OUTCOMES
    Mary McDermott; Fiscal Year: 2001
    ..They further state that the results of this study will be used to develop subsequent intervention studies designed to improve quality of life and prevent functional decline among men and women with PAD. ..
  41. TOSCA-2 An Angiographic Substudy of the Occluded Arter*
    Vladimir Dzavik; Fiscal Year: 2004
    ..The Data Coordinating Center (DCC) is the Maryland Medical Research Institute, the DCC of OAT. The An2iogiraphic Core Laboratory is at the University of British Columbia. ..
  42. Antiproliferative Rx for venous neointimal hyperplasia
    Prabir Roy Chaudhury; Fiscal Year: 2005
    ..We believe that the results from this study could transform the clinical care of hemodialysis patients and at the same time result in the successful clinical application of local therapy for the treatment of neointimal hyperplasia...
  43. PROSTAGLANDIN SIGNALING IN FEMALE REPRODUCTION
    John Reese; Fiscal Year: 2005
    ..The results of these experiments will enhance the understanding of maternal-fetal PG signaling, and are likely to provide new insights into premature or dysfunctional labor in women. ..
  44. MethLock vs. heparin as dialysis catheter lock
    Stephen Ash; Fiscal Year: 2008
    ..In Phase II we will implement the protocol in a number of dialysis centers and complete the study as originally proposed or as modified after Phase I. ..
  45. Chitosan hemostatic device for laparoscopic applications
    Hua Xie; Fiscal Year: 2005
    ..abstract_text> ..
  46. Magnetic Resonance in Peripheral Arterial Disease
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ..This knowledge, in subsequent studies, is expected to lead to new therapies for PAD-related functional impairment and functional decline. ..
  47. Vascular Access in Hemodialysis Patients
    Michael Allon; Fiscal Year: 2005
    ..The applicant will assist the trainees in acquiring the conceptual skills, research experience, and motivation required to pursue a successful career in Academic Nephrology. ..
  48. ROLE OF LAMININ-5 IN IMPLANT ASSOCIATED ANGIOGENESIS
    Stuart Williams; Fiscal Year: 2003
    ..Results from all these specific aims will provide an integrated evaluation of the role laminin 5 and the integrin alpha6beta4 in biomaterial associated angiogenesis. ..
  49. MICROSCOPIC CARDIAC MATERIAL PROPERTIES IN AGING
    Samuel Wickline; Fiscal Year: 2002
    ....
  50. SPECIFIC TISSUE TARGETED ULTRASONIC CONTRAST AGENT
    Samuel Wickline; Fiscal Year: 2002
    ....
  51. MORPHOLOGY AND FUNCTION OF BRAIN VESSELS
    GARY BAUMBACH; Fiscal Year: 2006
    ..These studies should provide important new insight into the mechanisms of vascular remodeling. [unreadable] [unreadable] [unreadable]..
  52. COLLABORATIVE R01-CARDIAC GRAFTS-FUNCTIONAL ANALYSES
    Robert Kloner; Fiscal Year: 2003
    ....
  53. Collagen-Binding Integrins in Intimal Hyperplasia
    Eric Choi; Fiscal Year: 2006
    ..Next, we plan to understand the role of collagenases in the interplay of SMC migration on native collagen. Finally, we will block the critical pathways of SMC migration in vivo to eliminate intimal lesion formation. ..
  54. Pheresis Treatment of Bioterrorism-Induced Sepsis
    Stephen Ash; Fiscal Year: 2005
    ..The safety systems of the existing PF system will be modified to meet the needs of the stand-alone system. Finally, an animal model of sepsis will be used to check efficacy and safety of the entire system. ..
  55. INFLAMMATORY MECHANISMS OF NEOINTIMAL HYPERPLASIA
    C Ozaki; Fiscal Year: 2004
    ..We hypothesize that Ill-10 downregulates neointimal hyperplasia. TNF-alpha and IL-10 mediated cellular processes serve as a potential site for therapeutically interrupting pathologic arterial remodeling. ..
  56. RADIATION ARTERIOPATHY IN A TRANSGENIC AV FISTULA MODEL
    Michael Lawton; Fiscal Year: 2004
    ..If NO and TGF-01 are involved in the radiation arteriopathy of AVMs, they might be used to enhance the efficacy of conventional stereotactic radiosurgery as part of a gene therapy for high-grade cerebral AVMs. ..
  57. Bioengineering of a Stent-Graft for Gene Therapy
    Hong Yu; Fiscal Year: 2005
    ..The host immune response to the transgene product canine F.IX will also be examined. The outcome of the project will have direct applications in the treatment of hemophilia as well as other blood and vascular disorders. ..
  58. Aging, Adenosine and Platelet-Mediated Thrombosis
    Karin Przyklenk; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  59. Articulated Robot for Epicardial Interventions
    Marco A Zenati; Fiscal Year: 2010
    ..We also believe that the HARP may expand the therapeutic options for other non-cardiac endoscopic applications . ..
  60. Mechanisms of Disability in Peripheral Arterial Disease
    Mary McDermott; Fiscal Year: 2005
    ..Results will be used to develop interventions designed to improve lower extremity functioning and prevent functional decline in persons with PAD. ..
  61. Improving Functioning in Peripheral Arterial Disease
    Mary McDermott; Fiscal Year: 2007
    ..By identifying the optimal exercise program for improving functioning in PAD patients with and without IC, our findings will have substantial clinical and public health implications for millions of patients with PAD. ..