venous pressure

Summary

Summary: The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.

Top Publications

  1. ncbi Venous hypertension, inflammation and valve remodeling
    S Takase
    Department of Bioengineering, The Whitaker Institute for Biomedical Engineering, University of California San Diego, La Jolla, CA 92093 0412, USA
    Eur J Vasc Endovasc Surg 28:484-93. 2004
  2. ncbi Hepatic venous pressure gradient can predict the development of hepatocellular carcinoma and hyponatremia in decompensated alcoholic cirrhosis
    Moon Young Kim
    Departments of Internal Medicine and Institute of Lifelong Health, Yonsei University Wonju College of Medicine, 162 Ilsan dong, Wonju, South Korea
    Eur J Gastroenterol Hepatol 21:1241-6. 2009
  3. pmc Relationship between the hepatic venous pressure gradient and first variceal hemorrhage in patients with cirrhosis: a multicenter retrospective study in Korea
    Jin Nyoung Kim
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea
    Clin Mol Hepatol 18:391-6. 2012
  4. ncbi [Measurement of hepatic venous pressure gradient in liver cirrhosis: relationship with the status of cirrhosis, varices, and ascites in Korea]
    Moon Young Kim
    Department of Internal Medicine and Institute of Lifelong Health, Yonsei University Wonju College of Medicine, Wonju, Korea
    Korean J Hepatol 14:150-8. 2008
  5. ncbi Hepatic venous pressure gradient in the assessment of portal hypertension before liver resection in patients with cirrhosis
    E Boleslawski
    Service de Chirurgie Digestive et Transplantations, Hopital Huriez, Centre hospitalier universitaire CHU, Université Nord de France, Lille, France
    Br J Surg 99:855-63. 2012
  6. ncbi The influence of abdominal pressure on lower extremity venous pressure and hemodynamics: a human in-vivo model simulating the effect of abdominal obesity
    T Willenberg
    Swiss Cardiovascular Centre, Division of Clinical and Interventional Angiology, University Hospital, Berne, Switzerland
    Eur J Vasc Endovasc Surg 41:849-55. 2011
  7. ncbi Comparison of hepatic venous pressure gradient and two models of end-stage liver disease for predicting the survival in patients with decompensated liver cirrhosis
    Ki Tae Suk
    Department of Internal Medicine Molecular Medicine, Hallym University College of Medicine, Chuncheon, South Korea
    J Clin Gastroenterol 46:880-6. 2012
  8. ncbi Identification of patients with decompensated cirrhosis at high risk for death: improving the prediction by hepatic venous pressure gradient?
    Seung Ha Park
    Department of Internal Medicine, Inje University College of Medicine, Busan, Korea
    Hepatogastroenterology 59:2548-51. 2012
  9. ncbi The hepatic venous pressure gradient: anything worth doing should be done right
    Roberto J Groszmann
    Digestive Diseases Section, the VA Connecticut Healthcare System, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06516, USA
    Hepatology 39:280-2. 2004
  10. ncbi Hepatic venous pressure gradient identifies patients at risk of severe hepatitis C recurrence after liver transplantation
    Alejandro Blasco
    Liver Unit, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Hepatology 43:492-9. 2006

Detail Information

Publications246 found, 100 shown here

  1. ncbi Venous hypertension, inflammation and valve remodeling
    S Takase
    Department of Bioengineering, The Whitaker Institute for Biomedical Engineering, University of California San Diego, La Jolla, CA 92093 0412, USA
    Eur J Vasc Endovasc Surg 28:484-93. 2004
    ..To identify possible mechanisms for destruction of valves in chronic venous hypertension and the results of treatment with an anti-inflammatory micronized purified flavonoid fraction...
  2. ncbi Hepatic venous pressure gradient can predict the development of hepatocellular carcinoma and hyponatremia in decompensated alcoholic cirrhosis
    Moon Young Kim
    Departments of Internal Medicine and Institute of Lifelong Health, Yonsei University Wonju College of Medicine, 162 Ilsan dong, Wonju, South Korea
    Eur J Gastroenterol Hepatol 21:1241-6. 2009
    ..We aimed to determine the relationship between hepatic venous pressure gradient (HVPG) and the development of HCC or low SNa in decompensated alcoholic cirrhosis patients.
  3. pmc Relationship between the hepatic venous pressure gradient and first variceal hemorrhage in patients with cirrhosis: a multicenter retrospective study in Korea
    Jin Nyoung Kim
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea
    Clin Mol Hepatol 18:391-6. 2012
    ..The development of gastroesophageal varices and variceal hemorrhage is the most direct consequence of portal hypertension. Correlations between the hepatic venous pressure gradient (HVPG) and first variceal hemorrhage were examined.
  4. ncbi [Measurement of hepatic venous pressure gradient in liver cirrhosis: relationship with the status of cirrhosis, varices, and ascites in Korea]
    Moon Young Kim
    Department of Internal Medicine and Institute of Lifelong Health, Yonsei University Wonju College of Medicine, Wonju, Korea
    Korean J Hepatol 14:150-8. 2008
    The relationships between the hepatic venous pressure gradient (HVPG) and the status of cirrhosis, complications of portal hypertension and the severity of cirrhosis are not clear...
  5. ncbi Hepatic venous pressure gradient in the assessment of portal hypertension before liver resection in patients with cirrhosis
    E Boleslawski
    Service de Chirurgie Digestive et Transplantations, Hopital Huriez, Centre hospitalier universitaire CHU, Université Nord de France, Lille, France
    Br J Surg 99:855-63. 2012
    Preoperative measurement of hepatic venous pressure gradient (HVPG) is not performed routinely before hepatectomy in patients with cirrhosis, although it has been suggested to be useful...
  6. ncbi The influence of abdominal pressure on lower extremity venous pressure and hemodynamics: a human in-vivo model simulating the effect of abdominal obesity
    T Willenberg
    Swiss Cardiovascular Centre, Division of Clinical and Interventional Angiology, University Hospital, Berne, Switzerland
    Eur J Vasc Endovasc Surg 41:849-55. 2011
    ..To demonstrate that abdominal pressure impacts venous flow and pressure characteristics...
  7. ncbi Comparison of hepatic venous pressure gradient and two models of end-stage liver disease for predicting the survival in patients with decompensated liver cirrhosis
    Ki Tae Suk
    Department of Internal Medicine Molecular Medicine, Hallym University College of Medicine, Chuncheon, South Korea
    J Clin Gastroenterol 46:880-6. 2012
    We evaluated the efficacy of initial and follow-up hepatic venous pressure gradient (HVPG), models of end-stage liver disease (MELD), and MELD-Na for predicting the survival of patients with decompensated liver cirrhosis (LC).
  8. ncbi Identification of patients with decompensated cirrhosis at high risk for death: improving the prediction by hepatic venous pressure gradient?
    Seung Ha Park
    Department of Internal Medicine, Inje University College of Medicine, Busan, Korea
    Hepatogastroenterology 59:2548-51. 2012
    The incremental usefulness of adding hepatic venous pressure gradient (HVPG) for predicting the risk of death has not, to our knowledge, been evaluated among patients with decompensated cirrhosis...
  9. ncbi The hepatic venous pressure gradient: anything worth doing should be done right
    Roberto J Groszmann
    Digestive Diseases Section, the VA Connecticut Healthcare System, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06516, USA
    Hepatology 39:280-2. 2004
  10. ncbi Hepatic venous pressure gradient identifies patients at risk of severe hepatitis C recurrence after liver transplantation
    Alejandro Blasco
    Liver Unit, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Hepatology 43:492-9. 2006
    ..We also explored the diagnostic value of hepatic venous pressure gradient (HVPG) to identify patients at risk of severe HCV disease recurrence after liver transplantation (LT)..
  11. ncbi Liver stiffness measurement as a predictive tool of clinically significant portal hypertension in patients with compensated hepatitis C virus or alcohol-related cirrhosis
    M Lemoine
    Service d Hepatologie, Hopital Jean Verdier, AP HP, Bondy, France
    Aliment Pharmacol Ther 28:1102-10. 2008
    Hepatic venous pressure gradient (HVPG) is the gold standard for assessing the presence and the severity of portal hypertension (PHT). Liver stiffness measurement (LSM) is a non-invasive method for liver fibrosis assessment.
  12. ncbi Does femoral venous pressure measurement correlate well with intrabladder pressure measurement? A multicenter observational trial
    Bart L De Keulenaer
    Intensive Care Unit, Fremantle Hospital, 1 Alma Street, Fremantle, WA 6160, Australia
    Intensive Care Med 37:1620-7. 2011
    To investigate if femoral venous pressure (FVP) measurement can be used as a surrogate measure for intra-abdominal pressure (IAP) via the bladder.
  13. ncbi Portal venous pressure changes after sequential clinical islet transplantation
    John J Casey
    Department of Surgical and Clinical Sciences Surgery, Royal Infirmary, Edinburgh, Scotland
    Transplantation 74:913-5. 2002
    ..Complications associated with the injection of islets into the portal vein have been reported; therefore, in this study we sought to further characterize changes in portal venous pressure associated with islet infusion.
  14. pdf Hepatic venous pressure gradient measurement in pre-primary and primary prophylaxis of variceal hemorrhage
    Julio D Vorobioff
    University of Rosario Medical School, 2000 Rosario, Argentina
    Ann Hepatol 12:22-9. 2013
    ..Hepatic venous pressure gradient (HVPG) measurement closely reflects portal pressure in most liver diseases whith predominant ..
  15. ncbi Clinical trial: The effect of somatostatin vs. octreotide in preventing post-endoscopic increase in hepatic venous pressure gradient in cirrhotics with bleeding varices
    J Vlachogiannakos
    2nd Department of Gastroenterology, Evangelismos Hospital, Athens, Greece
    Aliment Pharmacol Ther 26:1479-87. 2007
    Hepatic venous pressure gradient (HVPG) increases significantly after endoscopic therapy in patients with bleeding oesophageal varices, which may precipitate further haemorrhage...
  16. ncbi Hepatic venous pressure gradient does not correlate with the presence and the severity of portal hypertensive gastropathy in patients with liver cirrhosis
    Lia Bellis
    Haemodynamic Unit, Marino General Hospital, Via XXIV Maggio, 00047 Marino, Rome, Italy
    J Gastrointestin Liver Dis 16:273-7. 2007
    To evaluate whether the hepatic venous pressure gradient (HVPG) differs between cirrhotic patients with severe portal hypertensive gastropathy (PHG) and those with mild or absent PHG.
  17. ncbi Pulmonary venous pressure: relationship to pulmonary artery, pulmonary wedge, and left atrial pressure in normal, lightly sedated dogs
    Hari P Chaliki
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota, MN 55905, USA
    Catheter Cardiovasc Interv 56:432-8. 2002
    Because pulmonary venous pressure has never been measured, it is unclear whether pulmonary wedge pressure measures left atrial pressure, as commonly assumed, or pressure more upstream in the pulmonary venous or capillary beds...
  18. ncbi Diagnostic accuracy of hepatic venous pressure gradient measurement in the prediction of stage 1 compensated liver cirrhosis in patients with chronic hepatitis B
    Ki Tae Suk
    Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, South Korea
    Eur J Gastroenterol Hepatol 25:1170-6. 2013
    Hepatic venous pressure gradient (HVPG) of 6-10 mmHg has been accepted as a hemodynamic parameter of stage 1 compensated liver cirrhosis (LC)...
  19. ncbi The jugular venous pressure revisited
    John Michael S Chua Chiaco
    Cardiovascular Disease, John A Burns School of Medicine, University of Hawaii, Honolulu
    Cleve Clin J Med 80:638-44. 2013
    Assessment of the jugular venous pressure is often inadequately performed and undervalued...
  20. pmc Assessment of therapeutic benefit of antiviral therapy in chronic hepatitis C: is hepatic venous pressure gradient a better end point?
    A K Burroughs
    Royal Free Hospital, Liver Transplantation and Hepatobiliary Medicine, London, UK
    Gut 50:425-7. 2002
    ..However, changes in the hepatic venous pressure gradient (HVPG) may be considered as an adjunctive end point for the therapeutic evaluation of antiviral ..
  21. ncbi Value of hepatic venous pressure gradient measurement before liver resection for hepatocellular carcinoma
    S Stremitzer
    Department of General Surgery, Medical University Vienna, Vienna, Austria
    Br J Surg 98:1752-8. 2011
    ..This study assessed the role of preoperative hepatic venous pressure gradient (HVPG) assessment in identifying portal hypertension.
  22. ncbi Effect of sustained viral response on hepatic venous pressure gradient in hepatitis C-related cirrhosis
    Stuart Roberts
    Department of Gastroenterology, Alfred Hospital, Melbourne, Victoria, Australia
    Clin Gastroenterol Hepatol 5:932-7. 2007
    ..The aims of this study were to investigate the effect of treatment with peginterferon alfa-2a and ribavirin on hepatic venous pressure gradient (HVPG) in CHC with compensated cirrhosis.
  23. ncbi Prognostic value of hepatic venous pressure gradient in patients with compensated chronic hepatitis C-related cirrhosis
    Diego Rincon
    Hepatic Hemodynamic Laboratory, Liver Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Scand J Gastroenterol 48:487-95. 2013
    Hepatic venous pressure gradient (HVPG) is the main predictor of clinical decompensation in cirrhotic patients with compensated disease of any etiology without varices...
  24. ncbi The role of femoral venous pressure and femoral venous oxygen saturation in the setting of intra-abdominal hypertension: a pig model
    Adrian Regli
    Intensive Care Unit, Sir Charles Gairdner Hospital, Nedlands, Australia
    Shock 35:422-7. 2011
    ..this group of patients, we examined the impact of IAP and positive end-expiratory pressure (PEEP) on femoral venous pressure (FVP) and femoral venous oxygen saturation (Sfvo2) in an animal model...
  25. ncbi Hepatic venous pressure gradient determination in patients with hepatitis C virus-related and alcoholic cirrhosis
    Lia Bellis
    Department of Gastroenterology and Internal Medicine, Genzano Hospital E De Santis, Rome, Italy
    Eur J Gastroenterol Hepatol 15:1085-9. 2003
    ..This study was aimed at comparing the severity of portal hypertension in patients with HCV-related or alcoholic cirrhosis...
  26. ncbi Value of the hepatic venous pressure gradient to monitor drug therapy for portal hypertension: a meta-analysis
    Agustin Albillos
    Servicio de Gastroenterologia, Hospital Ramon y Cajal, Madrid, Spain
    Am J Gastroenterol 102:1116-26. 2007
    The use of the hepatic venous pressure gradient (HVPG) to assess the efficacy of the pharmacological treatment of portal hypertension in cirrhosis is controversial...
  27. ncbi Hepatic venous pressure gradient: worth another look?
    Sameer Parikh
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Dig Dis Sci 54:1178-83. 2009
    ..Measurement of the hepatic venous pressure gradient (HVPG) is a simple, invasive, and reproducible method of assessing portal venous pressure...
  28. ncbi Pathogenesis of primary chronic venous disease: Insights from animal models of venous hypertension
    John J Bergan
    Department of Surgery, University of California San Diego, 9850 Genesee, La Jolla, CA 92037, USA
    J Vasc Surg 47:183-92. 2008
    ..Reflux of blood through incompetent venous valves is a major cause of the venous hypertension that underlies clinical manifestations of chronic venous disease, including varicose veins, lipodermatosclerosis, and venous ulcers...
  29. ncbi Idiopathic elevated episcleral venous pressure and open-angle glaucoma
    D J Rhee
    Glaucoma Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Br J Ophthalmol 93:231-4. 2009
    To report a case series of Idiopathic Elevated Episcleral Venous Pressure (IEEVP).
  30. ncbi Computer-assisted image analysis of liver collagen: relationship to Ishak scoring and hepatic venous pressure gradient
    Vincenza Calvaruso
    The Royal Free Sheila Sherlock Liver Centre and Department of Surgery, Royal Free Hospital, London, UK
    Hepatology 49:1236-44. 2009
    ..We determined relationships between DIA, Ishak stage, and hepatic venous pressure gradient (HVPG) reflecting severity of fibrosis...
  31. ncbi Muscle blood flow response to contraction: influence of venous pressure
    Zoran Valic
    Departments of Anesthesiology and Physiology, Medical College of Wisconsin and VA Medical Center, 5000 W National Ave, Milwaukee, WI 53295, USA
    J Appl Physiol 98:72-6. 2005
    ..We hypothesized that increases in venous pressure within the muscle would enhance the effectiveness of the muscle pump and yield greater postcontraction ..
  32. ncbi Predictive value of the variceal pressure response to continued pharmacological therapy in patients with cirrhosis and portal hypertension
    A Escorsell
    Hepatic Hemodynamic Laboratory, Liver Unit, University of Barcelona, Barcelona, Spain
    Hepatology 31:1061-7. 2000
    ..Portal pressure was evaluated as the hepatic venous pressure gradient (HVPG). Over a 28 +/- 11 month follow-up, 16 patients experienced variceal bleeding...
  33. ncbi Computerized endoscopic balloon manometry to detect esophageal variceal pressure
    D R Kong
    Department and Key Laboratory of Gastroenterology, Anhui Geriatric Institute, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China
    Endoscopy 41:415-20. 2009
    ..The aims of the study were to test the in-vitro accuracy of CEBM and to evaluate the clinical reliability and feasibility of this method...
  34. ncbi Hepatic venous pressure gradient in cirrhosis: correlation with the size of varices, bleeding, ascites, and child's status
    M Wadhawan
    Department of Gastroenterology, G B Pant Hospital, New Delhi, 110002, India
    Dig Dis Sci 51:2264-9. 2006
    The hepatic venous pressure gradient (HVPG) clearly reflects portal pressure in cirrhotic portal hypertension. Its relation with variceal bleeding has been well studied...
  35. ncbi Raised venous pressure as a factor in multiple sclerosis
    David G Talbert
    Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, Du Cane Road, London W12 ONN, United Kingdom
    Med Hypotheses 70:1112-7. 2008
    ..However, if the DAVF outflow is entirely into the spine, intracranial venous pressure may be normal and so there is nothing to alert the clinician to the presence of an intracranial DAVF...
  36. ncbi Hepatic venous pressure gradient and prognosis in patients with acute variceal bleeding treated with pharmacologic and endoscopic therapy
    Juan G Abraldes
    Hepatic Hemodynamic Laboratory, Liver Unit, IMDiM, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Spain
    J Hepatol 48:229-36. 2008
    In acute variceal bleeding (AVB) hepatic venous pressure gradient (HVPG) is associated with prognosis. However, this has not been studied in patients receiving the currently recommended therapy...
  37. ncbi Third heart sound and elevated jugular venous pressure as markers of the subsequent development of heart failure in patients with asymptomatic left ventricular dysfunction
    Mark H Drazner
    Heart Failure Research Unit, Donald W Reynolds Cardiovascular Clinical Research Center, Dallas, Texas 75390, USA
    Am J Med 114:431-7. 2003
    To determine the independent prognostic value of a third heart sound (S(3)) and elevated jugular venous pressure in patients with asymptomatic left ventricular dysfunction.
  38. pmc The effect of vasopressin on choroidal blood flow, intraocular pressure, and orbital venous pressure in rabbits
    Barbara Bogner
    Department of Ophthalmology and Optometry, SALK Paracelsus Medical University, Salzburg, Austria
    Invest Ophthalmol Vis Sci 52:7134-40. 2011
    To investigate the effects of arginine-vasopressin (AVP) on intraocular pressure (IOP), orbital venous pressure (OVP), and choroidal blood flow (ChorBF) regulation in anesthetized rabbits.
  39. ncbi Prognostic importance of elevated jugular venous pressure and a third heart sound in patients with heart failure
    M H Drazner
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75390 9034, USA
    N Engl J Med 345:574-81. 2001
    The independent prognostic value of elevated jugular venous pressure or a third heart sound in patients with heart failure is not well established.
  40. ncbi Peripheral venous pressure as a hemodynamic variable in neurosurgical patients
    J R Munis
    Section of Anesthesia for Neurosurgery, Department of General Anesthesiology, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Anesth Analg 92:172-9. 2001
    ..yields a pressure that is traditionally measured at the superior vena cava and referred to as "central venous pressure" (CVP)...
  41. ncbi A rabbit model to study orbital venous pressure, intraocular pressure, and ocular hemodynamics simultaneously
    Herbert A Reitsamer
    Department of Physiology, University of Vienna Medical School, Austria
    Invest Ophthalmol Vis Sci 43:3728-34. 2002
    To measure orbital venous pressure (OVP) and determine the effects of changes in mean arterial pressure (MAP) on OVP, intraocular pressure (IOP), episcleral venous pressure (EVP), and ciliary and choroidal blood flows.
  42. ncbi Venous pressure monitoring does not accurately predict access failure in children
    Deepa H Chand
    Division of Pediatric Nephrology and Hypertension, A 120, The Cleveland Clinic Foundation, OH 44195, USA
    Pediatr Nephrol 17:765-9. 2002
    ..Routine monitoring of arteriovenous (AV) fistulas and grafts could increase access longevity. Dynamic venous pressure monitoring is a surveillance test advocated to detect early signs of vascular thrombosis...
  43. pmc Sildenafil does not influence hepatic venous pressure gradient in patients with cirrhosis
    Jens Otto Clemmesen
    Department of Hepatology A 2121, Rigshospitalet, Blegdamsvej 9, Copenhagen DK 2100, Denmark
    World J Gastroenterol 14:6208-12. 2008
    To investigate if sildenafil increases splanchnic blood flow and changes the hepatic venous pressure gradient (HVPG) in patients with cirrhosis...
  44. ncbi A case of renal impairment and raised venous pressure
    D F Johnston
    Colchester General Hospital, 2 Parker Road, Colchester, Essex CO4 5BE, UK
    Br J Radiol 80:499-501. 2007
  45. ncbi Prognostic value of hepatic venous pressure gradient for in-hospital mortality of patients with severe acute alcoholic hepatitis
    D Rincon
    Seccion de Hepatologia, Servicio de Aparato Digestivo, Hospital Gregorio Maranon, Madrid, Spain
    Aliment Pharmacol Ther 25:841-8. 2007
    Hepatic venous pressure gradient (HVPG) has prognostic value in complications and survival of patients with liver cirrhosis...
  46. ncbi Respiratory variations in the reflection mode photoplethysmographic signal. Relationships to peripheral venous pressure
    L Nilsson
    Department of Anaesthesiology and Intensive Care, Linkoping University Hospital, Linkoping, Sweden
    Med Biol Eng Comput 41:249-54. 2003
    ..healthy subjects, the respiratory synchronous variations from a PPG reflection mode signal and the peripheral venous pressure (PVP) were recorded...
  47. ncbi Episcleral venous pressure of mouse eye and effect of body position
    Makoto Aihara
    Hamilton Glaucoma Center, University of California San Diego, La Jolla, CA 92093 0946, USA
    Curr Eye Res 27:355-62. 2003
    To measure the episcleral venous pressure (EVP) of the mouse eye and to investigate the effect of body position on EVP and intraocular pressure (IOP).
  48. ncbi Regular monitoring of access flow compared with monitoring of venous pressure fails to improve graft survival
    Louise M Moist
    Department of Medicine, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
    J Am Soc Nephrol 14:2645-53. 2003
    ..studied time to graft thrombosis and graft loss, comparing monthly Qa plus standard surveillance (dynamic venous pressure and physical examination) (treatment group) to standard surveillance alone (control group)...
  49. ncbi Venous pressure measurements in the superior and inferior vena cava: the influence of intra-abdominal pressure
    N Markou
    B ICU, KAT Hospital, Athens, Greece
    Hepatogastroenterology 51:51-5. 2004
    ..To investigate the relationship of pressure in the inferior vena cava (Pivc) with a) pressure in the superior vena cava (Psvc), b) intra-abdominal pressure as measured in the urinary bladder (Pcyst)...
  50. ncbi Comparison of access blood flow and venous pressure measurements as predictors of arteriovenous graft thrombosis
    N Singh
    Department of Medicine, University at Buffalo, NY, USA
    J Vasc Access 7:66-73. 2006
    The purpose of the present study was to prospectively compare the predictive accuracy of static venous pressure (SVP); dynamic venous pressure (DVP) and access blood flow (ABF) in determining subsequent graft thrombosis and/or failure.
  51. ncbi Can transient elastography replace liver histology for determination of advanced fibrosis in alcoholic patients: a real-life study
    Filip Janssens
    Department of Gastroenterology, St Luc University Hospital, Universite Catholique de Louvain, Brussels, Belgium
    J Clin Gastroenterol 44:575-82. 2010
    ..We evaluated the performance of TE in predicting severe fibrosis (> or =F3) in alcoholic patients using cut-off values validated for chronic hepatitis C...
  52. ncbi Clinical trial: a randomized controlled study on prevention of variceal rebleeding comparing nadolol + ligation vs. hepatic venous pressure gradient-guided pharmacological therapy
    C Villanueva
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Aliment Pharmacol Ther 29:397-408. 2009
    Hepatic venous pressure gradient (HVPG) monitoring of therapy to prevent variceal rebleeding provides strong prognostic information. Treatment of nonresponders to beta-blockers +/- nitrates has not been clarified.
  53. ncbi Clinical outcome of HCV-related graft cirrhosis and prognostic value of hepatic venous pressure gradient
    Georgios Kalambokis
    The Royal Free Sheila Sherlock Liver Centre, University Department of Surgery, Royal Free Hospital, London, UK
    Transpl Int 22:172-81. 2009
    ..in 55 out of 234 consecutive patients and predictors of decompensation and mortality, including hepatic venous pressure gradient (HVPG) in 38...
  54. pmc Hepatic venous pressure gradient predicts development of hepatocellular carcinoma independently of severity of cirrhosis
    Cristina Ripoll
    Veterans Affairs CT Healthcare System, West Haven, CT 06516, USA
    J Hepatol 50:923-8. 2009
    ..Predictors of the development of hepatocellular carcinoma (HCC), including hepatic venous pressure gradient (HVPG) were analyzed.
  55. ncbi Mathematical model demonstrates influence of luminal diameters on venous pressure surveillance
    John J White
    Augusta VA Medical Center, and Section of Nephrology, Hypertension, and Renal Transplantation, Medical College of Georgia, Augusta, Georgia 30912, USA
    Clin J Am Soc Nephrol 2:681-7. 2007
    The reliability of dialysis venous pressure (VP) in detecting stenosis is controversial. A mathematical model may help to resolve the controversy by providing insight into the factors that influence static VP.
  56. ncbi Influence of hepatic venous pressure gradient on the prediction of survival of patients with cirrhosis in the MELD Era
    Cristina Ripoll
    Seccion de Hepatologia, Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Hepatology 42:793-801. 2005
    Measurements of portal pressure, usually obtained via the hepatic venous pressure gradient (HVPG) may be a prognostic marker in cirrhosis...
  57. ncbi [Comparison of the Model for End-stage Liver Disease and hepatic venous pressure gradient for predicting survival in patients with decompensated liver cirrhosis]
    Sung Hoa Lee
    Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea
    Korean J Hepatol 15:350-6. 2009
    This study compared the prognostic values of the Model for End-stage Liver Disease (MELD) and the hepatic venous pressure gradient (HVPG) in the prediction of death within 3 and 12 months in patients with decompensated liver cirrhosis.
  58. ncbi Vascular access surveillance: evaluation of combining dynamic venous pressure and vascular access blood flow measurements
    Heidi Hoeben
    Department of Medicine, Yale University, New Haven, Conn 06520 8029, USA
    Am J Nephrol 23:403-8. 2003
    ..Surveillance protocols utilizing venous pressure (Vp) and vascular access blood flow (VABF) measurements have been employed to preserve vascular access...
  59. ncbi Graft surveillance: venous pressure, access flow, or the combination?
    J H Smits
    Department of Nephrology, University Medical Center, The Netherlands
    Kidney Int 59:1551-8. 2001
    Increased venous pressure (VP) and decreased access flow (Qa) are predictors of dialysis access graft thrombosis. VP is easily obtainable. Qa assessment requires a special device and takes more time...
  60. ncbi Episcleral venous pressure in untreated primary open-angle and normal-tension glaucoma
    J Michael Selbach
    Department of Ophthalmology, University of Essen, Germany
    Ophthalmologica 219:357-61. 2005
    The aim of this prospective study was to investigate episcleral venous pressure (EVP) in different forms of glaucoma in comparison with age-matched controls...
  61. ncbi Peripheral venous pressure as a predictor of central venous pressure during orthotopic liver transplantation
    Nir Hoftman
    Department of Anesthesiology, David Geffen School of Medicine, UCLA Medical Center, Los Angeles, CA 90095 1778, USA
    J Clin Anesth 18:251-5. 2006
    To assess the reliability of peripheral venous pressure (PVP) as a predictor of central venous pressure (CVP) in the setting of rapidly fluctuating hemodynamics during orthotopic liver transplant surgery.
  62. ncbi Can peripheral venous pressure be interchangeable with central venous pressure in patients undergoing cardiac surgery?
    Roger Desjardins
    Department of Anesthesiology and Surgery, Montreal Heart Institute, 5000 Belanger Street East, H1T 1C8, Montreal, Quebec, Canada
    Intensive Care Med 30:627-32. 2004
    ..There is growing interest in the use of peripheral venous sites for estimating central venous pressure (CVP)...
  63. ncbi The efficacy of a new portable sequential compression device (SCD Express) in preventing venous stasis
    Stavros K Kakkos
    Department of Vascular Surgery, Faculty of Medicine, Imperial College, London, United Kingdom
    J Vasc Surg 42:296-303. 2005
    ..The aim of our study was to test the hemodynamic effectiveness of a new portable sequential compression system (the SCD Express), which has the ability to detect the individual refill time of the two lower limbs separately...
  64. ncbi Losartan in preascitic cirrhosis
    Gustavo Castano
    Am J Gastroenterol 99:2282-3. 2004
  65. ncbi Calf muscle pump stimulation as an adjunct to orthopaedic surgery
    Victor H Frankel
    NYU Hospital for Joint Diseases Orthopaedic Institute, New York, New York, USA
    Surg Technol Int 14:297-304. 2005
    ....
  66. ncbi Hyperemic maximal venous outflow unmasks symptomatic lower extremity venous obstruction
    David J Paolini
    Jobst Vascular Center, The Toledo Hospital, Toledo, Ohio 43606, USA
    J Vasc Surg 48:749-53. 2008
    ..A postocclusive reactive hyperemic technique was used to unmask significant outflow obstruction, leading to operative correction and subsequent symptom resolution...
  67. ncbi Prevalence of portal hypertensive duodenopathy in cirrhosis: clinical and haemodynamic features
    Luis Menchén
    Servicios de Aparato Digestivo, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    Eur J Gastroenterol Hepatol 18:649-53. 2006
    ..To estimate the prevalence of portal hypertensive duodenopathy (PHD) in patients with cirrhosis and portal hypertension, and to evaluate its relationship with clinical and haemodynamic parameters...
  68. ncbi HR, 0-(beta-hydroxyethyl)-rutosides, in comparison with diosmin+hesperidin in chronic venous insufficiency and venous microangiopathy: an independent, prospective, comparative registry study
    M R Cesarone
    Irvine2 Vasc Lab and Physiology, Department of Biomedical Sciences, Chieti University, San Valentino Vascular Screening Project, Italy
    Angiology 56:1-8. 2005
    ..The comparison with D+H indicates that HR is comparatively more effective both on microcirculatory parameters and on signs/symptoms of CVI...
  69. ncbi Influence of beta-2 adrenergic receptor gene polymorphism on the hemodynamic response to propranolol in patients with cirrhosis
    Juan Turnes
    Hepatic Hemodynamic Laboratory, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, IDIBAPS, Barcelona, Spain
    Hepatology 43:34-41. 2006
    ..However, HVPG reduction cannot be predicted from polymorphism analysis. Patients with the Gly16-Glu/Gln27 haplotypes may benefit from the association of hepatic vasodilators to propranolol therapy...
  70. ncbi The venous return simulator: an effective tool for investigating the effects of external compression on the venous hemodynamics--first results after thigh compression
    J M Fullana
    Service de Biophysique, Laboratoires Innothera, Arcueil, France
    Vasa 34:19-23. 2005
    ..To present a virtual model, the venous return simulator (VRS), designed to compute venous hemodynamic variations when compression is applied to the leg...
  71. ncbi Assessment of the agreement between wedge hepatic vein pressure and portal vein pressure in cirrhotic patients
    U Thalheimer
    Liver Transplantation and Hepatobiliary Medicine Unit, Royal Free Hospital, Pond Street, NW3 2QG London, UK Internal Medicine Dept, Policlinico G B Rossi, Piazzale L A Scuro, Verona, Italy
    Dig Liver Dis 37:601-8. 2005
    Measuring wedged hepatic venous pressure and hepatic venous pressure gradient as indices of portal pressure is being increasingly used in assessing the prognosis and response to pharmacological treatment for portal hypertension in ..
  72. ncbi [Pharmacological therapy of portal hypertension--focused on Korean data]
    Soon Koo Baik
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Ilsan dong, Wonju, Korea
    Korean J Gastroenterol 45:381-6. 2005
    ..The hepatic venous pressure gradient has been accepted as the gold-standard method for assessing the severity of portal hypertension and ..
  73. ncbi The impact of gastrocnemius muscle cell changes in chronic venous insufficiency
    T Qiao
    Department of Vascular Surgery, Drum Tower Hospital, Affiliated Hospital of Medical College, Nanjing University, Nanjing 210008, China
    Eur J Vasc Endovasc Surg 30:430-6. 2005
    ..To investigate the pathological and metabolic changes in the gastrocnemius muscle in patients with chronic vein insufficiency (CVI)...
  74. ncbi Improvement of microcirculation and healing of venous hypertension and ulcers with Crystacide: evaluation with a microcirculatory model, including free radicals, laser doppler flux, and PO2/PCO2 measurements
    Gianni Belcaro
    Irvine Vascular Laboratory and Physiology, Department of Biomedical Sciences, Chieti University, San Valentino Vascular Screening Project, PE, Italy
    Angiology 58:323-8. 2007
    ..In conclusion, in chronic venous insufficiency and venous ulcerations, local treatment with Crystacide (10 days) improves the microcirculation and decreases skin free radicals, thus improving healing...
  75. ncbi [Principles of hemodynamics and sonographic techniques for the evaluation of veins of the neck and limbs]
    Ph Bonnin
    Service de Physiologie, Explorations Fonctionnelles, Pr B Levy, Hopital Lariboisiere, 2 rue A Pare, 75 475 Paris Cedex 10
    J Radiol 86:629-37. 2005
    ..Venography is thus rarely performed. The sensitivity for the diagnosis of deep venous thrombosis at the neck level is up to 90%. Follow-up can easily be performed because of the wide availability of US...
  76. ncbi Endovenous saphenous ablation corrects the hemodynamic abnormality in patients with CEAP clinical class 3-6 CVI due to superficial reflux
    William A Marston
    Division of Vascular Surgery, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7212, USA
    Vasc Endovascular Surg 40:125-30. 2006
    ..These techniques are useful for treatment of patients with more severe clinical classes of superficial CVI...
  77. ncbi Mathematical model for the hemodynamic response to venous occlusion measured with near-infrared spectroscopy in the human forearm
    Toi Van Vo
    Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA
    IEEE Trans Biomed Eng 54:573-84. 2007
    ..These results indicate that this mathematical model can be a valuable analytical tool to characterize, optimize, and further develop diagnostic measurement schemes that use venous occlusion approaches...
  78. ncbi Systematic review of HVPG measurement: statistics versus clinical applicability
    Ulrich Thalheimer
    Gastroenterology 132:1201-2; author reply 1202-4. 2007
  79. ncbi Hemodynamic impairment, venous segmental disease, and clinical severity scoring in limbs with Klippel-Trenaunay syndrome
    Konstantinos T Delis
    Division of Vascular Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Vasc Surg 45:561-7. 2007
    ..With the purpose of determining the actual significance of venous impairment in patients with KTS, we quantified the venous valvular competency and calf muscle pump function and examined their effect on clinical severity...
  80. ncbi Effect of carvedilol on portal hypertension depends on the degree of endothelial activation and inflammatory changes
    Radan Bruha
    4th Medical Department, General Teaching Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Scand J Gastroenterol 41:1454-63. 2006
    ..The aim of study was to assess the correlation between the therapeutic efficacy of carvedilol and markers of endothelial dysfunction and systemic inflammation in patients with liver cirrhosis and portal hypertension...
  81. ncbi Damping index of Doppler hepatic vein waveform to assess the severity of portal hypertension and response to propranolol in liver cirrhosis: a prospective nonrandomized study
    Moon Young Kim
    Department of Internal Medicine and Institute of Lifelong Health, Wonju College of Medicine, Yonsei University, Wonju, South Korea
    Liver Int 27:1103-10. 2007
    ..We prospectively evaluated the correlation between the extent of abnormal Doppler HV waveforms expressed as damping index (DI) and the hepatic venous pressure gradient (HVPG) and response to propranolol in patients with cirrhosis.
  82. ncbi Rapid relief of signs/symptoms in chronic venous microangiopathy with pycnogenol: a prospective, controlled study
    M R Cesarone
    Irvine2 Vascular Lab and Physiology, Department of Biomedical Sciences, G Annunzio, Chieti Pescara University, San Valentino Vascular Screening Project, Faculty of Motory Sciences, L Aquila University, Italy
    Angiology 57:569-76. 2006
    ..Also the 18 controls completed the follow-up period. There were no drop-outs. The average ambulatory venous pressure was 59.3 (SD 7.2; range 50-68) with a refilling time shorter than 10 seconds (average 7.6; SD 3)...
  83. ncbi Conception of the venous hemodynamics in the lower extremity
    C Recek
    Vienna, Austria
    Angiology 57:556-63. 2006
    ..b>Venous pressure difference arising between the popliteal and the posterior tibial vein during the activity of the calf muscle ..
  84. ncbi Impact of the calf perforators on the venous hemodynamics in primary varicose veins
    C Recek
    Division of Vascular Surgery, Department of Surgery, University Hospital, Hradec Kralove, Czech Republic
    J Cardiovasc Surg (Torino) 47:629-35. 2006
    ..The size of the calf perforators is determined by the amount of saphenous reflux. When the saphenous reflux is abolished (e.g. by high ligation), the enlarged calf perforators diminish...
  85. ncbi Haemodynamic and clinical assessment of lateral marginal vein excision in patients with a predominantly venous malformation of the lower extremity
    Y W Kim
    Division of Vascular Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Eur J Vasc Endovasc Surg 33:122-7. 2007
    ..The purpose of the present study was to determine the effects of the surgical excision of lateral marginal veins (LMVs) in patients with a venous malformation (VM) affecting the lower extremity...
  86. ncbi Mechanisms in experimental venous valve failure and their modification by Daflon 500 mg
    L Pascarella
    Department of Surgery University of California San Diego, La Jolla, CA, USA
    Eur J Vasc Endovasc Surg 35:102-10. 2008
    ..To characterize the acute response of the vein wall to venous hypertension and associated altered fluid shear stress and to test the effect of micronized purified flavonoid fraction (MPFF, Daflon 500), on this response...
  87. ncbi Role of percutaneous transhepatic obliteration for special types of varices with portal hypertension
    F Chikamori
    Department of Surgery, Kuniyoshi Hospital, 1 3 4 Kamimachi, Kochi City, Kochi 780 0901, Japan
    Abdom Imaging 32:92-5. 2007
    ..The special types of varices were successfully embolized in all cases and there were no complications. We conclude that the PTO is still an effective and safe treatment for special types of varices with portal hypertension...
  88. ncbi Leg ulcer recurrence and its risk factors: a duplex ultrasound study before and after vein surgery
    M B Magnusson
    Department of Clinical Physiology, Cardiovascular Institute, Goteborg, Sweden
    Eur J Vasc Endovasc Surg 32:453-61. 2006
    ..Assessment of risk factors for ulcer recurrence in chronic leg ulcer patients treated by varicose vein surgery...
  89. ncbi High blood flow rates with adjustment of needle diameter do not increase hemolysis during hemodialysis treatment
    F Techert
    Georg Haas Dialysis Center, Giessen, Germany
    J Vasc Access 8:252-7. 2007
    ..Higher blood flow in dialysis therapy is often avoided due to concerns about shear-induced blood damage despite the lack of reliable data...
  90. ncbi O-(beta-hydroxyethyl)-rutosides systemic and local treatment in chronic venous disease and microangiopathy: an independent prospective comparative study
    Gianni Belcaro
    Department of Biomedical Sciences, Chieti Pescara University, and the San Valentino Vascular Screening Project, Italy
    Angiology 59:7S-13S. 2008
    ..The study is based on evaluation of microcirculatory variables in patients with severe CVI (ambulatory venous pressure, > 56 mm Hg) and venous microangiopathy...
  91. ncbi [Surgery for deep venous reflux in the lower limb]
    M Perrin
    Chirurgie Vasculaire, Lyon, France
    Praxis (Bern 1994) 95:464-8. 2006
    ..Valve agenesis is very rare. Clinical examination frequently does not allow distinguishing between superficial and deep venous insufficiency. In addition primary reflux is difficult to identify from secondary deep reflux...
  92. ncbi 5-Year control and treatment of edema and increased capillary filtration in venous hypertension and diabetic microangiopathy using O-(beta-hydroxyethyl)-rutosides: a prospective comparative clinical registry
    Gianni Belcaro
    Department of Biomedical Sciences, Chieti Pescara University, and the San Valentino Vascular Screening Project, Italy
    Angiology 59:14S-20S. 2008
    ..The prevention of ulcerations with HR is another important observation. The effects of HR seem to be partially dose related, and tolerability and compliance are good...
  93. ncbi Venous valve reconstruction in patients with secondary chronic venous insufficiency
    A Rosales
    Faculty of Medicine, Oslo Vascular Centre, Aker University Hospital, University of Oslo, Oslo, Norway
    Eur J Vasc Endovasc Surg 36:466-72. 2008
    ....
  94. ncbi Monitoring the changes in intraparenchymatous venous pressure to ascertain flap viability
    Hiroyuki Sakurai
    Department of Plastic and Reconstructive Surgery, Tokyo Women s Medical University, Kawada cho, Shinjuku ku, Tokyo, Japan
    Plast Reconstr Surg 119:2111-7. 2007
    ..The authors have devised an approach with which to monitor the changes in venous pressure in a composite tissue transferred by means of microsurgical technique for bodily reconstruction.
  95. ncbi The venous reflux
    C Recek
    Angiology 55:541-8. 2004
    ..Large incompetent calf perforators are not the cause of venous abnormality but are the consequence of saphenous retrograde flow...
  96. ncbi Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemodynamics
    Uwe J F Tietge
    Dept of Medicine, NWFZ, 5 Ebene, Charite Campus Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    Am J Physiol Endocrinol Metab 287:E82-9. 2004
    ....
  97. ncbi The value of serum-ascites albumin gradient for the determination of portal hypertension in the diagnosis of ascites
    S Dittrich
    , RS, Brazil
    Hepatogastroenterology 48:166-8. 2001
    ..to paracentesis and blood examination to determine the serum-ascites albumin gradient and the hepatic venous pressure gradient was measured. RESULTS: Mean serum-ascites albumin gradient was 2.0 g/dL in group 1 and 0...
  98. ncbi Early surgical management of Klippel-Trenaunay syndrome in childhood can prevent long-term haemodynamic effects of distal venous hypertension
    V Baraldini
    Milan, Italy
    J Pediatr Surg 37:232-5. 2002
    ..The aim of this study was to evaluate the authors' preliminary experience in early surgical treatment of distal venous hypertension (DVH) in children affected by Klippel-Trenaunay syndrome (KTS)...
  99. ncbi Intrahepatic heterogeneity of hepatic venous pressure gradient in human cirrhosis again
    S Keiding
    Scand J Gastroenterol 37:1344. 2002
  100. ncbi Prospective evaluation of chronic venous insufficiency based on foot venous pressure measurements and air plethysmography findings
    Masato Fukuoka
    Department of Cardiovascular, Thoracic and Pediatric Surgery, Kobe University Graduate School of Medicine, 7 5 2 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    J Vasc Surg 38:804-11. 2003
    The purpose of this study was to evaluate lower extremity venous function in patients with chronic venous insufficiency, with foot venous pressure (FVP) measurements and air plethysmography (APG).
  101. ncbi Plasma erythropoietin level in patients with cirrhosis and its relationship to the severity of cirrhosis and renal function
    Ying Ying Yang
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, National Yang Ming University School of Medicine, and Institute of Traditional Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    J Gastroenterol Hepatol 18:1156-61. 2003
    ..The current study was undertaken to evaluate the relationship between plasma EPO levels and the severity of liver disease, hemodynamic values, renal functions, and plasma nitrate/nitrite levels in patients with cirrhosis...

Research Grants63

  1. Omega-3 Fatty Acids, Neurohumoral Activation, and Human Heart Failure
    Kevin D Monahan; Fiscal Year: 2010
    ..Doppler ultrasound estimates of renal blood flow velocity and whole limb blood flow, [central venous pressure], and numerous biochemical measures to assess the state of neurohumoral activation...
  2. Detection and Quantification of Neonatal Intraventricular Hemorrhage
    Michael D Weiss; Fiscal Year: 2013
    ..Many physiologic disturbances (e.g., loss of cerebral blood flow autoregulation, increased central venous pressure, hypotension) have been associated with IVHs through retrospective studies, but exact cause-effect ..
  3. HEMODYNAMICS OF CEREBRAL ARTERIOVENOUS MALFORMATIONS
    Hua Su; Fiscal Year: 2013
    ..We will test the effect of increased flow and venous pressure, and their interaction to produce dysplasia...
  4. Mechanisms of Cardiac Function and Cerebral Vascular Control during Heat Stress
    Robert Matthew Brothers; Fiscal Year: 2010
    ..Specific Aim 1: Tests the hypothesis that restoration of central blood volume (indexed by central venous pressure) during heat stress improves blood pressure control and orthostatic tolerance...
  5. Mechano-Sensitive Hypoxia-Inducible Factor-MMP Pathway in Venous Insufficiency
    Raouf A Khalil; Fiscal Year: 2013
    ..CVI commonly occurs in the lower extremity, suggesting a role of venous pressure and vein wall stretch...
  6. Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension
    Flemming Forsberg; Fiscal Year: 2013
    ..Consequently, the development of an accurate and noninvasive technique for measurement of portal venous pressure would represent a major advance in the diagnosis and management of portal hypertension...
  7. Aqueous Humor Dynamic Components that Determine Intraocular Pressure Variance
    Sayoko E Moroi; Fiscal Year: 2013
    ..measures are the physiological components of IOP, namely, aqueous humor inflow, outflow facility, episcleral venous pressure, and uveoscleral outflow...
  8. Noninvasive and Accurate Measurement of Portal Hypertension
    Flemming Forsberg; Fiscal Year: 2010
    ..Consequently, the development of an accurate noninvasive technique for measurement of portal venous pressure would represent a major advance in the diagnosis and management of portal hypertension...
  9. Quantitative Hemodynamics of the Liver with 4D Flow MRI
    Oliver Wieben; Fiscal Year: 2013
    ..Portal hypertension is currently assessed using invasive catheter-based measurements of hepatic venous pressure gradient (HVPG)...
  10. Assessing Use of Acoustic Radiation Force to Noninvasively Measure Liver Pressure
    VERONICA MIRIAM ROTEMBERG; Fiscal Year: 2013
    ..liver diseases includes a combination of serum testing, liver biopsy, and, as the disease progresses, hepatic venous pressure gradient (HVPG) measurement...
  11. TRPV1 mediation of local vasoconstrictor reflexes in spinal cord injured humans
    Dean L Kellogg; Fiscal Year: 2013
    ..The VAR occurs when venous pressure increases more than 25mmHg and causes a reduction in blood flow probably by distention of stretch receptors ..
  12. Factors Determining Protein Losing Enteropathy
    Hudson H Freeze; Fiscal Year: 2012
    ..that localized loss of HSPG, plus a general systemic pro-inflammatory condition in a setting of increased venous pressure causes PLE. Our preliminary data supports a robust synergism of these factors...
  13. Ocular blood flow and intraocular pressure homeostasis
    Jeffrey W Kiel; Fiscal Year: 2013
    ..The project's goal for this cycle is to increase our knowledge of episcleral venous pressure (EVP) and its regulation. This is important for two reasons...
  14. MICROVASCULAR PERMEABILITY OF THE CEREBRAL CIRCULATION
    WILLIAM MAYHAN; Fiscal Year: 1992
    ..and disruption of the BBB in veins was associated with, and presumably due to, increases in pial venous pressure. Experiments that are proposed will examined the determinants of disruption in veins...
  15. Piezoelectric Pump to supply Ventricular Assist Device for Fontan Patients
    CONAL O'NEILL; Fiscal Year: 2013
    ..demonstrate that the system can increase fluid flow through the pulmonary circulation while reducing systemic venous pressure in a mock Fontan fluidic circuit...
  16. PILOT STUDY OF PIRFENIDONE IN PBC AND PSC
    Keith Lindor; Fiscal Year: 1999
    ..and (3) to evaluate the clinical antifibrotic activity of pirfenidone on portal hypertension (hepatic venous pressure gradient and gastroesophageal varices) in portal hypertensive patients with PBC and on the severity of bile ..
  17. REGULATION OF TRABECULAR CELL GLYCOPROTEINS
    John Samples; Fiscal Year: 1991
    ..which are thought to impede outflow and maintain a normal intraocular pressure of approximately 7 mm above venous pressure. The purpose of this proposal is to study signals involved in the regulation of trabecular cells with respect ..
  18. INTERACTION OF CARDIOVASCULAR REFLEXES IN EXERCISE
    Gary Mack; Fiscal Year: 1992
    ..characteristics of each baroreflex by selectively manipulating either carotid sinus transmural or central venous pressure. The linear relationship between forearm vascular resistance (FVR) and CVP determined during low levels of ..
  19. Noninvasive Quantification of the Resistance Baroeflex
    Ramakrishna Mukkamala; Fiscal Year: 2006
    ..with atrio-ventricular (AV) block and instrumented for cardiac pacing and measurement of ABP, CO, and central venous pressure (CVP)...
  20. PHYSIOLOGIC BENEFITS OF BIVENTRICULAR PACING IN CHF
    Mohamed Hamdan; Fiscal Year: 2002
    ..During phase 1 and 2, arterial pressure, central venous pressure and muscle sympathetic nerve activity using microneurography will be recorded during sinus rhythm, atrial ..
  21. FEEDING, ISCHEMIA, & OXYGENATION IN DEVELOPING INTESTINE
    KAREN CRISSINGER; Fiscal Year: 1991
    ..and 1 month will be utilized to measure total and fractionated blood flow, arteriovenous oxygen difference, venous pressure, and capillary pressure...
  22. Bridge to neonatal Fontan repair of single ventricle
    Mark Rodefeld; Fiscal Year: 2006
    ..We further hypothesize that the neonate will tolerate the systemic venous pressure elevation required to permit passive venous flow through the lungs...
  23. ASSESSMENT OF DIASTOLIC FUNCTION IN HUMANS
    James Thomas; Fiscal Year: 1999
    ..or across the atrial septum (cath lab) to obtain high fidelity left atrial, ventricular and pulmonary venous pressure. Simultaneous transesophageal echocardiographic acquisitions of mitral valve and pulmonary venous pulsed ..
  24. PEPTIDE AND PROBE MODULATION OF AQUEOUS DYNAMICS
    Theodore Krupin; Fiscal Year: 1993
    ..Noninvasive measurements of outflow facility, episcleral venous pressure and aqueous humor flow will be performed...
  25. CAPILLARY & INTERSTITIAL FLUID & SOLUTE EXCHANGE
    Donald Bell; Fiscal Year: 1991
    ..Data obtained following plasmapheresis will be compared to data obtained after increased venous pressure to test the hypothesis that decreasing plasma oncotic pressure effects the restrictive compartment while ..
  26. REGULATION OF CIRCULATION TO BRAIN STEM
    Frank Faraci; Fiscal Year: 1991
    ..acute hypertension, but the blood-brain barrier is protected in the brain stem because increases in pial venous pressure are attenuated...
  27. REGULATION OF VENOUS MUSCLE K+ CHANNELS
    NANCY RUSCH; Fiscal Year: 1993
    ..For the chronic, non- invasive elevation of venous pressure we propose to use the tilt technique, that was developed by our group...
  28. THERMODILUTION RIGHT VENTRICULAR EJECTION FRACTION
    WILLIAM SANTAMORE; Fiscal Year: 1999
    ..A catheter (tube) is placed in the right heart through a vein. From this catheter, central venous pressure and pulmonary artery pressure can be measured...
  29. EFFECT OF ATRIAL NATRIURETIC FACTOR IN HUMANS
    Thomas Ebert; Fiscal Year: 1992
    ..of previous studies has been the lack of control of cardiac filling pressures during ANF infusions: central venous pressure and pulmonary capillary wedge pressure decline significantly during infusions...
  30. Real Time Risk of Mortality in Critically III Children
    DANIEL KOCIS; Fiscal Year: 2005
    ..e. temperature, heart rate, blood pressure, central venous pressure, pulsed oximetry, and end tidal carbon dioxide concentrations); b...
  31. VENOUS SOURCE FOR BLEEDING IN GERMINAL MATRIX HEMORRHAGE
    DIXON MOODY; Fiscal Year: 2002
    ..predisposing to GMH concern unstable arterial blood pressure, ischemic brain injury, and wide swings in venous pressure. Certain large, fragile germinal matrix (GM) periventricular vascular "channels" from which bleeding often ..
  32. MICROVASCULAR CONTROL OF CAPILLARY HYDROSTATIC PRESSURE
    Michael Davis; Fiscal Year: 1991
    ..in the entire microcirculation will be measured as arterial pressure (Pa) is lowered, and as Pa and venous pressure are raised. Possible disruption of normal control mechanisms by micropressure pipettes will be evaluated...
  33. Basis of Post-Fontan Protein Losing Enteropathy
    Hudson Freeze; Fiscal Year: 2006
    ..of HSPG, plus a general systemic pro-inflammatory condition within the Fontan-induced setting of increased venous pressure cause PLE. Our preliminary in vitro data supports a robust synergism of these factors...
  34. REGULATORY REFLEXES FROM ISOLATED PULMONARY
    JERRY GREEN; Fiscal Year: 1991
    ..In particular, we shall examine the response of lung C-fibers to CO2, elevations of pulmonary venous pressure and varying concentrations of ozone...
  35. FLUOROPHOTOMETRIC DETERMINATION--AQUEOUS HUMOR DYNAMICS
    MICHAEL YABLONSKI; Fiscal Year: 1992
    ..the fluorophotometric method, that acetazolamide and timolol do not affect uveoscleral outflow and episcleral venous pressure will also be tested...
  36. PRESSURE VENTILATION AND NEONATAL CEREBRAL HEMODYNAMICS
    CHARLES LEFFLER; Fiscal Year: 1992
    Positive pressure ventilation causes increases and fluctuations in cerebral venous pressure. Preliminary studies suggest that pressure ventilation selectively disrupts the blood-brain barrier in newborn pigs...
  37. PRESSURE VENTILATION AND NEONATAL CEREBRAL HEMODYNAMICS
    ROBERT MIRRO; Fiscal Year: 1991
    Positive pressure ventilation causes increases and fluctuations in cerebral venous pressure. Preliminary studies suggest that pressure ventilation selectively disrupts the blood-brain barrier in newborn pigs...
  38. CAPILLARY MORPHOLOGY IN PULMONARY EDEMA
    ROBERT MAZZONE; Fiscal Year: 1980
    ..Dog lungs will be ventilated and perfused in situ and edema will be induced by increasing pulmonary venous pressure. Lungs will then be frozen under the following conditions: (1) alveolar pressure exceeds pulmonary artery ..
  39. MARIJUANA AND GLAUCOMA
    Walter Jay; Fiscal Year: 1980
    ..application of marijuana derivatives on intraocular pressure, outflow facility, scleral rigidity, episcleral venous pressure, pseudofacility, and aqueous flow in human eyes; 3) to evaluate these compounds in normal eyes, in eyes with ..
  40. Building an Artificial Trabecular Meshwork
    DONNA PETERS; Fiscal Year: 2007
    ..Fluid pressure in each chamber and across cells can be controlled to mimic intraocular pressure, episcleral venous pressure and the tissue's transcellular pressure gradient respectively, allowing fluid flow across the cell-..
  41. LUNG MICROCIRCULATION WITH HIGH VASCULAR PRESSURES
    Mary Townsley; Fiscal Year: 1999
    As a result of congestive heart failure or mitral stenosis, venous pressure in the pulmonary circulation is chronically elevated. Despite the venous hypertension, alveolar flooding and respiratory distress do not always occur...
  42. INTESTINAL SECRETION: CAPILLARY AND TISSUE FORCES
    D Granger; Fiscal Year: 1980
    ..induced by various agents (humoral and pharmacological) and physiological maneuvers (plasma dilution, venous pressure elevation)...
  43. Improving Flow Dynamics in Fontan Surgeries
    Ajit Yoganathan; Fiscal Year: 2006
    ..improvements in post-TCPC hemodynamics achieved by treating congenital abnormalities associated with the ascending aorta; (vi) determine the feasibility of reducing post-TCPC central venous pressure using a pressure regulator/pump.
  44. Detecting Endothelial Dysfunction in Renal Failure
    Julian Stewart; Fiscal Year: 2007
    ..These data will form the basis of future noninvasive prognostic testing and treatment of patients at risk for ECD and can provide a means to follow treatment modalities. [unreadable] [unreadable] [unreadable]..
  45. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2004
    ..by impedance plethysmography, and limb blood flow, arterial flow, venous volume-pressure relation, and venous pressure will be measured by venous occlusion strain gauge plethysmography...
  46. Skin Blood Flow in Diabetes: Local and Reflex Control
    Nisha Charkoudian; Fiscal Year: 2007
    ....
  47. SARCOPENIA--UNDERLYING MECHANISMS
    Barry Dworkin; Fiscal Year: 2003
    ..abstract_text> ..
  48. CONTROL OF VASCULAR TONE BY CONTINGENT CNS STIMULATION
    Barry Dworkin; Fiscal Year: 2006
    ....
  49. Pathophysiological Interpretations of Dynamic PET/CT of Molecular Liver Biology
    Susanne Keiding; Fiscal Year: 2010
    ..This will lead to improved diagnosis and treatment of the large groups of patients with liver disease and cancer in the liver. ..
  50. ESOPHAGEAL VARICES BY B-ADRENERGIC BLOCKERS
    Roberto Groszmann; Fiscal Year: 2003
    ....
  51. Integrity of the Pulmonary Blood-Gas Barrier
    John West; Fiscal Year: 2007
    ..In addition, at the more basic level, this research is devoted to a fundamental biological dilemma of the lung, namely how the blood-gas barrier combines extreme thinness with immense strength. [unreadable] [unreadable]..
  52. Thrombus resolution is CXC chemokine dependent
    Peter Henke; Fiscal Year: 2006
    ..abstract_text> ..
  53. Evaluation of New Imaging Methodologies at 7T
    EWART HAACKE; Fiscal Year: 2007
    ..Many of the approaches developed and applied on this animal system are expected to have important clinical impact. All of these projects will substantially benefit from the proposed acquisition. [unreadable] [unreadable] [unreadable]..
  54. Heart Failure and Beta-Blocker Use in Older Adults
    Ali Ahmed; Fiscal Year: 2006
    ..abstract_text> ..
  55. Novel Strategies Targeting Acute Exacerbation of COPD
    Richard Albert; Fiscal Year: 2007
    ..This information will, at the same time, also provide information regarding the pathobiology of COPD exacerbations. ..
  56. US Prostate Cancer Detection with Dutasteride Pretreatment
    Ethan Halpern; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  57. Neural and non-neural modulators of skin blood flow and sweating in humans
    CRAIG CRANDALL; Fiscal Year: 2009
    ..e. diabetes, heart failure, etc) and non-disease (i.e. aging) conditions. ..
  58. Heart failure, chronic kidney disease, and renin-angiotensin system inhibition
    Ali Ahmed; Fiscal Year: 2009
    ....
  59. Integrative Cardiovascular Control During Exercise in Hypertension
    DONAL S O apos LEARY; Fiscal Year: 2010
    ....
  60. Estrogen & Progesterone Effects on Orthostatic Tolerance
    NINA STACHENFELD; Fiscal Year: 2010
    ..We also expect that the data in these studies will provide a basis to study the impact of sex hormones on diseases related to compromised peripheral circulation, such as hypertension, Raynaud's phenomenon and diabetes ..
  61. MRS Detects Metabolic Dysfunction after Brain Injury
    Paul Vespa; Fiscal Year: 2009
    ..The knowledge from the proposed studies will have widespread application to critical care of neurotrauma patients. ..
  62. Short-term mesenteric lymphatic adaptation to trauma-related intestinal edema
    Emily Wilson; Fiscal Year: 2010
    ..When interstitial pressure exceeds central venous pressure, lymphatic vessels can act as conduit vessels, passively transporting lymph down a pressure gradient...
  63. Post Traumatic Nonconvulsive Epileptiform Activity
    Paul Vespa; Fiscal Year: 2005
    ..The hypothesis and unique approach come at a crucial time of failed clinical trials and address an important new therapeutic target. ..