Genomes and Genes
Summary: Nonsusceptibility of a microbe to the action of ampicillin, a penicillin derivative that interferes with cell wall synthesis.
Publications219 found, 100 shown here
- Two different mechanisms of ampicillin resistance operating in strains of Vibrio cholerae O1 independent of resistance genesDong Tu Nguyen
Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
FEMS Microbiol Lett 298:37-43. 2009..The twitching motility in the fimbriate Bgd17 strain disappeared depending on the production of cpxP protein, suggesting that fimbriation of V. cholerae O1 is controlled by a two-component signal transduction system...
- Genome-wide identification of ampicillin resistance determinants in Enterococcus faeciumXinglin Zhang
Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
PLoS Genet 8:e1002804. 2012..in the low-affinity penicillin binding protein PBP5 have previously been shown to be important for ampicillin resistance in E. faecium, but the existence of additional resistance determinants has been suggested...
- Multidrug resistance is mediated by large plasmids carrying a class 1 integron in the emergent Salmonella enterica serotype [4,5,12:i:-]B Guerra
, , Universidad de Oviedo, 33006 Oviedo, Principado de Asturias, Spain
Antimicrob Agents Chemother 45:1305-8. 2001..The genes mediating resistance to ampicillin, chloramphenicol, and tetracycline in the [4,5,12:i:-] clone are different from those found in the pentadrug-resistant serotype Typhimurium DT104 clone...
- Spread of ampicillin/vancomycin-resistant Enterococcus faecium of the epidemic-virulent clonal complex-17 carrying the genes esp and hyl in German hospitalsI Klare
Robert Koch Institute, Wernigerode Branch, Burgstr 37, 38855, Wernigerode, Germany
Eur J Clin Microbiol Infect Dis 24:815-25. 2005..In conclusion, it is very important to monitor the occurrence of epidemic-virulent clonal complex-17 strains of E. faecium to prevent their spread in hospitals, especially if they are resistant to glycopeptides and linezolid...
- Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in KoreaIn Suk Kim
Department of Laboratory Medicine, Gyeong Sang University College of Medicine, Jinju, Korea
Antimicrob Agents Chemother 51:453-60. 2007..influenzae strains in Korea...
- Polymorphisms of the pbp5 gene and correlation with ampicillin resistance in Enterococcus faecium isolates of animal originPatricia Poeta
Departamento de Ciências Veterinárias, Universidade de Tras os Montes e Alto Douro, Vila Real, Portugal
J Med Microbiol 56:236-40. 2007..The other two alleles presented the amino acid changes 496N-->K and 629E-->V (allele D), and 470H-->Q (allele F). A correlation between deduced amino acid changes in PBP5 and ampicillin MICs was detected in animal E. faecium isolates...
- Risk factors associated with ampicillin resistance in patients with bacteraemia caused by Enterococcus faeciumJesus Fortun
Department of Infectious Diseases, Ramon y Cajal Hospital, University of Alcala, Crtra Colmenar Km 9 1, Madrid 28034, Spain
J Antimicrob Chemother 50:1003-9. 2002..12-20.0) and urinary catheterization (OR:4.2; 95% CI: 1.3-30.0) were identified as predictors of ampicillin resistance in enterococcal bacteraemic patients...
- vanA and vanB incorporate into an endemic ampicillin-resistant vancomycin-sensitive Enterococcus faecium strain: effect on interpretation of clonalityJ P Suppola
Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, 00014 Helsinki, Finland
J Clin Microbiol 37:3934-9. 1999..None of the differences was specific to or determinative for any of the groups. Our material suggests that vanA and vanB incorporate into an endemic ampicillin-resistant VSE strain...
- Trends in antimicrobial resistance in 3469 enterococci isolated from blood (EARSS experience 2001-06, Spain): increasing ampicillin resistance in Enterococcus faeciumJesús Oteo
J Antimicrob Chemother 59:1044-5. 2007
- Biomonitoring marine habitats in reference to antibiotic resistant bacteria and ampicillin resistance determinants from oviductal fluid of the nesting green sea turtle, Chelonia mydasS N al-Bahry
Department of Biology, College of Science, Sultan Qaboos University, PC 123, Al Khodh, Muscat, Oman
Chemosphere 87:1308-15. 2012..This data can be of value in understanding the decline of this endangered species as a result of exposure to marine pollution which is threatening their survival...
- Importance of amino acid alterations and expression of penicillin-binding protein 5 to ampicillin resistance of Enterococcus faecium in TaiwanSue Er Hsieh
Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, no 11, Buzih Lane, Beitun District, Taichung City 40601, Taiwan, Republic of China
Int J Antimicrob Agents 28:514-9. 2006..in the C-terminal domain of penicillin-binding protein 5 (PBP5) and the levels of PBP5 expression to ampicillin resistance of Taiwan clinical isolates of Enterococcus faecium were studied...
- Role of penicillin-binding protein 5 in expression of ampicillin resistance and peptidoglycan structure in Enterococcus faeciumF Sifaoui
INSERM E0004, , 75270 Paris Cedex 06, France
Antimicrob Agents Chemother 45:2594-7. 2001..These results indicate that pbp5 is a nonessential gene responsible for intrinsic resistance to moderate levels of ampicillin and by itself cannot confer high-level resistance...
- Transfer of ampicillin resistance from Salmonella Typhimurium DT104 to Escherichia coli K12 in foodC Walsh
The Ashtown Food Research Centre, Teagasc, Ashtown, Dublin, Ireland
Lett Appl Microbiol 46:210-5. 2008..To investigate the transfer of antibiotic resistance from a donor Salmonella Typhimurium DT104 strain to a recipient Escherichia coli K12 strain...
- Analysis of clonality and antibiotic resistance among early clinical isolates of Enterococcus faecium in the United StatesJessica R Galloway-Peña
Department of Internal Medicine, Division of Infectious Diseases, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA
J Infect Dis 200:1566-73. 2009..The Enterococcus faecium genogroup, referred to as clonal complex 17 (CC17), seems to possess multiple determinants that increase its ability to survive and cause disease in nosocomial environments...
- Identification of high-risk enterococcal clonal complexes: global dispersion and antibiotic resistanceHelen L Leavis
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Curr Opin Microbiol 9:454-60. 2006..This complex is correlated with ampicillin and quinolone resistance and with the presence of a putative pathogenicity island. Preliminary MLST data suggest that similar hospital-adapted complexes might also exist in E. faecalis...
- Molecular characterisation of bovine faecal Escherichia coli shows persistence of defined ampicillin resistant strains and the presence of class 1 integrons on an organic beef farmD V Hoyle
Medical Microbiology, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG, UK
Vet Microbiol 115:250-7. 2006..coli. The prevalence of ampicillin resistance ranged from 27.3 to 40...
- Ecological replacement of Enterococcus faecalis by multiresistant clonal complex 17 Enterococcus faeciumJ Top
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Centre Utrecht, Utrecht, The Netherlands
Clin Microbiol Infect 13:316-9. 2007..This ecological change mimics events preceding the emergence of vancomycin-resistant E. faecium (VREF) in the USA and may presage the emergence of CC17 VREF in European hospitals...
- Analysis of PBP5 of early U.S. isolates of Enterococcus faecium: sequence variation alone does not explain increasing ampicillin resistance over timeJessica R Galloway-Peña
Division of Infectious Disease, Department of Medicine, Center for the Study of Emerging and Re Emerging Pathogens, University of Texas Medical School, Houston, Texas 77030, USA
Antimicrob Agents Chemother 55:3272-7. 2011Recent studies have shown that ampicillin resistance has increased steadily over the past 3 decades within U.S. Enterococcus faecium isolates...
- Penicillin-binding protein 5 and expression of ampicillin resistance in Enterococcus faeciumL B Rice
Medical and Research Services, VA Medical Center, Cleveland, Ohio 44106, USA
Antimicrob Agents Chemother 45:1480-6. 2001..transcripts varied between strains and did not always correlate with quantities of PBP5 or levels of ampicillin resistance. Since the psr of C68 is presumably nonfunctional due to an insertion of an extra nucleotide in the codon ..
- Acquisition and epidemiology of antibiotic-resistant Escherichia coli in a cohort of newborn calvesDeborah V Hoyle
Centre for Tropical Veterinary Medicine, Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG
J Antimicrob Chemother 53:867-71. 2004..The acquisition of antibiotic-resistant commensal Escherichia coli was examined in a cohort of newborn calves...
- Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genesThithiwat May
Graduate School of Engineering, Hokkaido University, Kita 13, Nishi 8, Kita ku, Sapporo 060 8628, Japan
Antimicrob Agents Chemother 53:4628-39. 2009..Here we showed the interplay between the tetracycline resistance efflux pump TetA(C) and the ampicillin resistance gene (bla(TEM-1)) in biofilms of Escherichia coli harboring pBR322 in the presence of the mixture of ..
- Natural transfer of sulphonamide and ampicillin resistance between Escherichia coli residing in the human intestineMargarita Trobos
National Center for Antimicrobials and Infection Control, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
J Antimicrob Chemother 63:80-6. 2009..The aim of this study was to investigate whether the sulphonamide resistance gene sul2 could be transferred between Escherichia coli in the human gut...
- [The trend and susceptibility to antibacterial agents of enterococcus species from urinary tract infections]Kiyohito Ishikawa
Department of Urology, School of Medicine, Fujita Health University
Nihon Hinyokika Gakkai Zasshi 95:25-34. 2004..To determine the extent of drug-resistance among Enterococcus species we investigated in vitro experiments...
- High acquisition and environmental contamination rates of CC17 ampicillin-resistant Enterococcus faecium in a Dutch hospitalMarieke J A de Regt
Department of Medical Microbiology, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
J Antimicrob Chemother 62:1401-6. 2008..In Europe, CC17 isolates are usually ampicillin-resistant, but most are still vancomycin-sensitive. We aimed to study ampicillin-resistant E. faecium (ARE) epidemiology in our hospital...
- Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of blaTEM genes in swine fecesD Bibbal
UMR181 Physiopathologie et Toxicologie Expérimentales, INRA, ENVT, Ecole Nationale Veterinaire de Toulouse, 23 Chemin des Capelles, BP 87 614, Toulouse Cedex 3, France
Appl Environ Microbiol 73:4785-90. 2007The aim of this study was to assess the impact of three ampicillin dosage regimens on ampicillin resistance among Enterobacteriaceae recovered from swine feces by use of phenotypic and genotypic approaches...
- Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNAHong Ming Shen
Department of Molecular Genetics and Cell Biology, University of Chicago, IL 60637, USA
Mol Cell Biol 25:10815-21. 2005..On the other hand, the lack of mutations in the first approximately 100 nucleotides and beyond about 1 to 2 kb from the promoter of immunoglobulin genes during SHM must be due to special conditions of transcription and chromatin in vivo...
- Changing patterns in neonatal Escherichia coli sepsis and ampicillin resistance in the era of intrapartum antibiotic prophylaxisMatthew J Bizzarro
Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520 8064, USA
Pediatrics 121:689-96. 2008The goal was to determine current trends in Escherichia coli-related early- and late-onset sepsis and patterns of ampicillin resistance in relation to institutional changes in the use of intrapartum antibiotic prophylaxis.
- Longer intestinal persistence of Enterococcus faecalis compared to Enterococcus faecium clones in intensive-care-unit patientsPatricia Ruiz-Garbajosa
Servicio de Microbiologia, Hospital Universitario Ramon y Cajal, Madrid, Spain
J Clin Microbiol 47:345-51. 2009..faecalis showed a cumulative increase in CDPD, whereas E. faecium did not. CDPD and CPR were useful for measuring the dynamics of intestinal colonization with enterococcal clones...
- Ampicillin-resistant Escherichia coli in gestational pyelonephritis: increased occurrence and association with the colonization factor Dr adhesinA Hart
Departments of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA
J Infect Dis 183:1526-9. 2001The pattern of ampicillin resistance and possible association with virulence factors of 78 Escherichia coli isolates taken from 78 pregnant women with pyelonephritis were evaluated...
- High occurrence of esp among ampicillin-resistant and vancomycin-susceptible Enterococcus faecium clones from hospitalized patientsTeresa M Coque
Servicio de Microbiologia, Hospital Ramon y Cajal, Carretera de Colmenar, Km 9 1, Madrid 28034, Spain
J Antimicrob Chemother 50:1035-8. 2002..faecium clones. This observation indicates that antibiotic-resistant variants may frequently arise under antibiotic selective pressure among esp-positive clones reaching ecological abundance in the nosocomial habitat...
- Impact of specific pbp5 mutations on expression of beta-lactam resistance in Enterococcus faeciumLouis B Rice
Medical and Research Services, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio 44106, USA
Antimicrob Agents Chemother 48:3028-32. 2004We tested the impact of individual PBP 5 mutations on expression of ampicillin resistance in Enterococcus faecium using a shuttle plasmid designed to facilitate expression of cloned pbp5 in ampicillin-susceptible E. faecium D344SRF...
- Transformation of Coxiella burnetii to ampicillin resistanceM L Suhan
Department of Microbiology and Immunology, Health Sciences Center, West Virginia University, Morgantown, 26506 9177, USA
J Bacteriol 178:2701-8. 1996..176:5233-5243, 1994). In the present study, an ars replicon was used to transform C. burnetii to ampicillin resistance. Plasmid pSKO(+)1000 contained the C...
- Lack of detection of ampicillin resistance gene transfer from Bt176 transgenic corn to culturable bacteria under field conditionsEsther Badosa
Institute of Food and Agricultural Technology, CIDSAV CeRTA, University of Girona, , Girona Spain
FEMS Microbiol Ecol 48:169-78. 2004..9%. Specific detection of putative bacteria harbouring bla TEM-1 ampicillin resistance genes acquired from Bt176 corn was performed with a method based on the extraction of DNA from the ..
- Photoactivatable antisense DNA: suppression of ampicillin resistance in normally resistant Escherichia coliF P Gasparro
Department of Dermatology, Yale University, New Haven, CT 06510
Antisense Res Dev 1:117-40. 1991..Bacteria treated in a similar manner but in the presence of tetracycline instead of ampicillin were not affected. The activity of beta-galactosidase, whose gene is located on the same plasmid as beta-lactamase, was not affected...
- Ampicillin-resistant enterococci in a Swedish university hospital: nosocomial spread and risk factors for infectionE Torell
Department of Medical Sciences, Uppsala University Hospital, Sweden
Scand J Infect Dis 33:182-7. 2001..Infection control measures focusing on protecting patients at high risk for ARE infections and further efforts to optimize antimicrobial use are proposed...
- Outbreak of ampicillin-resistant Enterococcus faecium--risk factors for faecal colonisationS C Mohn
Department for Infection Control, Haukeland Hospital and University of Bergen, Norway
APMIS 108:296-302. 2000..Prolonged antimicrobial therapy and broad-spectrum antibiotics seem to facilitate nosocomial ARE colonisation...
- Worldwide variation in the incidence of Haemophilus influenzae type b meningitis and its association with ampicillin resistanceB D Gessner
Association pour l Aide a la Medecine Preventive, Institut Pasteur, Paris, France
Eur J Clin Microbiol Infect Dis 21:79-87. 2002..In contrast, antibiotic use may contribute to the observed differences in incidence...
- [Profile of antimicrobial resistance of agents causing urinary tract infections in children]Leila Ghedira Besbes
Service de Pediatrie, Hopital Fattouma Bourguiba, Monastir, Tunisie
Tunis Med 82:299-305. 2004..The management of urinary tract infection in children faces the problem of the emergence of resistant strains to antibiotics. The aim of this study is to precise the frequency of the different germs and their susceptibility to antibiotics...
- [Isolation of beta-lactamase non-producing ampicillin-resistant Haemophilus influenzae (BLNAR) and analysis of its PBP3 gene]Fumihiro Yamaguchi
Department of Clinical Pathology, Showa University, School of Medicine, Shinagawa ku, Tokyo 142 8666
Rinsho Byori 56:662-70. 2008..5 or microg/ml. When a noticeable MIC increase of ABPC or other beta-lactams in the routine clinical laboratory practice, gene analysis of ftsI gene of the isolates displaying increased MIC is required to measure the spreading of BLNAR...
- Invasive Haemophilus influenzae disease in adults in TaiwanChien Chun Wang
Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, and National Yang Ming University, Taipei, Taiwan
J Microbiol Immunol Infect 41:209-14. 2008..We conducted a retrospective survey of invasive H. influenzae disease in adults in order to better understand the characteristics of clinical presentation and microbiology...
- [Surveillance of antimicrobial susceptibility of Haemophilus influenzae isolates from children in Beijing, Shanghai, and Guangzhou 2000 - 2002]Xu zhuang Shen
Beijing Children s Hospital, Capital University of Medical Sciences, Beijing 100045, China
Zhonghua Yi Xue Za Zhi 84:1335-9. 2004..To investigate the situation of antibiotic resistance of Haemophilus influenzae isolates from Chinese children...
- [In vitro combined effect of meropenem and various antimicrobial agents against beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae and penicillin-resistant Streptococcus pneumoniae]Katsunori Kanazawa
Discovery Research Laboratories II, Research Division, Sumitomo Pharmaceuticals Co, Ltd, 3 1 98, Kasugade Naka, Konohana ku, Osaka 554 0022, Japan
Jpn J Antibiot 58:168-78. 2005..These findings suggest that combination therapy with MEPM and various antimicrobial agents tested in this study are useful in treating bacterial meningitis caused by BLNAR and PRSP...
- [The prevalence of beta-lactamase negative ampicillin resistant Haemophilus influenzae in Mie Prefecture]Tokuyoshi Maruyama
Division of Blood Transfusion, Mie University Hospital
Kansenshogaku Zasshi 78:891-7. 2004..In this study, six (8.1%) of 74 isolates were found to be BLNAR, and all of these six isolates were derived from patients of 5 year-old or younger...
- Population structure of Enterococcus faecium causing bacteremia in a Spanish university hospital: setting the scene for a future increase in vancomycin resistance?Teresa M Coque
Departamento de Microbiologíca, Servicio de Microbiologia, Hospital Universitario Ramon y Cajal, Carretera de Colmenar, Km 9 1, Madrid 28034, Spain
Antimicrob Agents Chemother 49:2693-700. 2005..in Spain, a country characterized by a near-absence of resistance to vancomycin and very high rates of ampicillin resistance among enterococci...
- Resistance to beta-lactamase inhibitor protein does not parallel resistance to clavulanic acid in TEM beta-lactamase mutantsWilliam A Schroeder
Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada
Antimicrob Agents Chemother 46:3568-73. 2002..The slight increases in resistance to inhibition by BLIP seen in the mutants may have been related to the fact that all of the mutations effected changes in the net charge on the TEM protein that could impede interactions with BLIP...
- Occurrence of plasmid-mediated ampicillin resistance among enterobacteria from the ovine rumenR Malik
Institute of Animal Physiology, Slovak Academy of Sciences, 040 01 Kosice, Slovakia
Folia Microbiol (Praha) 49:187-90. 2004..The small tem1 carrying plasmid and its transfer (mobilization) was detected and partially characterized after conjugation to laboratory Escherichia coli strain...
- Genetic and molecular characterization of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae with unusually high resistance to ampicillinFrank S Kaczmarek
Department of Immunology and Infectious Disease, Pfizer Global Research and Development, Groton, Connecticut 06340, USA
Antimicrob Agents Chemother 48:1630-9. 2004..In an effort to determine the presence of additional mechanism(s) of ampicillin resistance, sequencing of the transpeptidase regions of pbp1a, -1b, and -2 was performed...
- Rapidly increasing prevalence of beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae type b in patients with meningitisKeiko Hasegawa
Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5 9 1 Shirokane, Minato ku, Japan
Antimicrob Agents Chemother 48:1509-14. 2004..Pulsed-field gel electrophoresis suggested the rapid spread of specific H. influenzae type b strains throughout Japan. Expedited vaccination, rapid identification, and judicious antibiotic use could slow their spread...
- Hypermutable Haemophilus influenzae with mutations in mutS are found in cystic fibrosis sputumMichael E Watson
Seattle Biomedical Research Institute, 307 Westlake Ave N, Suite 500, Seattle, WA 98109, USA
Microbiology 150:2947-58. 2004..Hypermutable H. influenzae with mutations in mutS are prevalent, particularly in the CF lung environment, and may be selected for and maintained by antibiotic pressure...
- Self-transmissible antibiotic resistance to ampicillin, streptomycin, and tetracyclin found in Escherichia coli isolates from contaminated drinking waterSatish K Walia
Department of Biological Sciences, Oakland University, Rochester, Michigan 48309, USA
J Environ Sci Health A Tox Hazard Subst Environ Eng 39:651-62. 2004..These data raise an important question about the impact of E. coli containing self-transmissible R-plasmids as a potential reservoir of virulence genes in drinking water...
- Comparative analysis of amplified fragment length polymorphism and pulsed field gel electrophoresis in a hospital outbreak and subsequent endemicity of ampicillin-resistant Enterococcus faeciumRoland Jureen
Institute of Medicine, University of Bergen, 5021 Bergen, Norway
FEMS Immunol Med Microbiol 40:33-9. 2004..The findings indicate that PFGE and AFLP are equally discriminative and could in this setting be used for typing purposes over the whole 5-year period...
- Epidemiology of nalidixic acid resistance and TEM-1- and TEM-52-mediated ampicillin resistance of Shigella sonnei isolates obtained in Korea between 1980 and 2000Young Sook Jeong
Department of Microbiology, Kyungpook National University School of Medicine, Taegu 700 422, Korea
Antimicrob Agents Chemother 47:3719-23. 2003..Ampicillin and nalidixic acid resistance was found in 30 and 86% of the isolates, respectively. The ampicillin resistance was mediated by a TEM-1 beta-lactamase, and TEM-52 extended-spectrum beta-lactamase was identified in one ..
- In vitro and in vivo activities of novel 2-(thiazol-2-ylthio)-1beta-methylcarbapenems with potent activities against multiresistant gram-positive bacteriaYutaka Ueda
Discovery Research Laboratories II, Sumitomo Pharmaceuticals, Research Division, Konohana, Osaka 554 0022, Japan
Antimicrob Agents Chemother 47:2471-80. 2003....
- Molecular characterisation and mechanisms of resistance of multidrug-resistant human Salmonella enterica serovar Typhimurium isolated in Amiens (France)Maurice Biendo
Laboratoire de Bactériologie et Hygiène, CHU Nord, Place Victor Pauchet, 80054 Amiens, Cedex 1, France
Int J Antimicrob Agents 26:219-29. 2005..3%) and IF (27.4%) were considered as epidemic patterns. The dendrogram obtained from S. Typhimurium pulsotypes allowed five clones (S1-S5) to be identified, with two prevalent clones comprising 47.8% (S2) and 27.3% (S4) of the isolates...
- In vitro effect of the presence of human albumin or human serum on the bactericidal activity of daptomycin against strains with the main resistance phenotypes in Gram-positivesF Cafini
Microbiology Department, School of Medicine, Universidad Complutense, Avda Complutense s n, Madrid, Spain
J Antimicrob Chemother 59:1185-9. 2007..5 mg/L), protein binding (91.7% versus 36.9%) and thus theoretical free-drug fractions (4.7 versus 16.1 mg/L)...
- Influence of Haemophilus influenzae beta-lactamase production and/or ftsI gene mutations on in vitro activity of and susceptibility rates to aminopenicillins and second- and third-generation cephalosporinsJ Garcia-de-Lomas
Int J Antimicrob Agents 30:190-2. 2007
- Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefiximeSilvia García-Cobos
Antibiotic Laboratory, Bacteriology Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
Antimicrob Agents Chemother 51:2564-73. 2007..BLNAR H. influenzae strains have arisen by vertical and horizontal spread and have evolved to adapt rapidly to the increased selective pressures posed by the use of oral penicillins and cephalosporins...
- Evaluation of ceftobiprole medocaril against Enterococcus faecalis in a mouse peritonitis modelCesar A Arias
Center for the Study of Emerging and Reemerging Pathogens, Division of Infectious Diseases, University of Texas Medical School at Houston, 6431 Fannin Street, MSB 2 112, Houston, TX 77030, USA
J Antimicrob Chemother 60:594-8. 2007..The objective of this study was to assess the in vivo activity of ceftobiprole against four strains of E. faecalis, including beta-lactamase- producing (Bla+) and vancomycin-resistant strains...
- Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae?Dewan Sakhawat Billal
Antimicrob Agents Chemother 51:3463-4. 2007
- Are beta-lactam breakpoints adequate to define non-susceptibility for all Haemophilus influenzae resistance phenotypes from a pharmacodynamic point of view?L Alou
Microbiology Department, School of Medicine, Universidad Complutense, Avda Complutense s n, 28040 Madrid, Spain
J Antimicrob Chemother 59:652-7. 2007....
- Antimicrobial susceptibility and coagulase gene typing of Staphylococcus aureus isolated from bovine clinical mastitis cases in TurkeyL Guler
Veterinary Control and Research Institute, Konya, Turkey
J Dairy Sci 88:3149-54. 2005..8% of the isolates typed. The results indicate that a few coagulase gene types of S. aureus are responsible for the majority of bovine clinical mastitis cases in one province of Central Anatolia region, Turkey...
- Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in JapanMuneki Hotomi
Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, 811 1 Kimiidera, Wakayama Shi, Wakayama, 641 8509, Japan
Antimicrob Agents Chemother 51:3969-76. 2007..influenzae among medical centers in Japan. The gBLNAR strains show a remarkable prevalence among H. influenzae isolates, with the prevalence increasing with time. This fact should be taken into account when treating URT infections...
- Antibacterial activity and PK/PD of ceftriaxone against penicillin-resistant Streptococcus pneumoniae and beta-lactamase-negative ampicillin-resistant Haemophilus influenzae isolates from patients with community-acquired pneumoniaAkira Ohno
Departments of Microbiology and Infectious Disease, Faculty of Medicine, Toho University, 5 21 16 Omorinishi, Ota ku, Tokyo 143 8540, Japan
J Infect Chemother 13:296-301. 2007..Ceftriaxone has an excellent balance between in vitro antimicrobial activities and pharmacokinetic profiles; and therefore remains effective as a therapeutic agent against PRSP and BLNAR H. influenzae in CAP...
- Presence of vancomycin and ampicillin-resistant Enterococcus faecium of epidemic clonal complex-17 in wastewaters from the south coast of EnglandJonathan L Caplin
Schools of Environment and Technology, University of Brighton, Brighton BN2 4GJ, UK
Environ Microbiol 10:885-92. 2008....
- Proteomic analysis of ampicillin-resistant oral Fusobacterium nucleatumM Al-Haroni
Department of Oral Sciences Oral Microbiology, Faculty of Dentistry, and Centre of International Health, University of Bergen, Bergen, Norway
Oral Microbiol Immunol 23:36-42. 2008..Penicillin-resistant F. nucleatum have been isolated from intra- and extraoral infections. This study aimed to assess ampicillin resistance in F. nucleatum by investigating the synthesis of resistance-associated proteins.
- Antimicrobial resistance of Haemophilus influenzae isolated from the nasopharynx of Japanese children with acute otitis mediaMuneki Hotomi
Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan
Acta Otolaryngol 126:240-7. 2006..A high prevalence of penicillin-binding protein gene-mutated (PGM) strains of Haemophilus influenzae should be taken into account when treating otitis media in children...
- High prevalence of type b beta-lactamase-non-producing ampicillin-resistant Haemophilus influenzae in meningitis: the situation in Japan where Hib vaccine has not been introducedKeiko Hasegawa
Laboratory of Infectious Agents Surveillance, Kitasato Institute for Life Sciences, Kitasato University 5 9 1, Shirokane, Minato ku, Tokyo, Japan
J Antimicrob Chemother 57:1077-82. 2006....
- Genetic analyses of beta-lactamase negative ampicillin-resistant strains of Haemophilus influenzae isolated in Okinawa, JapanToru Kubota
First Department of Internal Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa 903 0215, Japan
Jpn J Infect Dis 59:36-41. 2006....
- Antibiotic susceptibility of invasive Haemophilus influenzae strains in CanadaMichelle L Sill
Vaccine Preventable Bacterial Diseases, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
Antimicrob Agents Chemother 52:1551-2. 2008..5% were beta-lactamase negative ampicillin intermediate, and 2.5% were intermediate to only the 2-microg ampicillin disk. An increase in beta-lactamase-negative ampicillin-intermediate strains has been found...
- Antimicrobial effect of fluoroquinolones for the eradication of nontypeable Haemophilus influenzae isolates within biofilmsChiharu Kaji
Department of Internal Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan
Tohoku J Exp Med 214:121-8. 2008..The results of this study suggest that fluoroquinolones potentially have a role in therapy against diseases caused by both BLNAS and BLNAR NTHi isolates within biofilms...
- High nasopharyngeal carriage of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae in north Indian school-going childrenAmita Jain
Department of Microbiology, King George s Medical University, Lucknow, U P India
J Infect Chemother 14:72-4. 2008Development of ampicillin resistance in Haemophilus influenzae is a cause of serious concern. Ampicillin resistance in H influenzae is beta-lactamase mediated except in some isolates...
- [Current status of PRSP and BLNAR]Muneki Hotomi
Department of Otolaryngology Head and Neck Surgery, Wakayama Medical University
Nihon Rinsho 65:441-7. 2007
- Species prevalence and antibacterial resistance of enterococci isolated in Kuwait hospitalsEdet E Udo
Department of Microbiology, Faculty of Medicine, Kuwait University, PO Box 24923, Safat 13110, Kuwait
J Med Microbiol 52:163-8. 2003..All of the vancomycin-resistant strains carried the vanA phenotype and genotype. There was no evidence of clonal spread of the vancomycin-resistant isolates...
- [Haemophilus influenzae: phenotype characteristics of strains isolated in 12 Catalan hospitals over one year]Cristina Latorre
Servicio de Microbiologia, Hospital universitario Sant Joan de Déu Barcelona España
Enferm Infecc Microbiol Clin 21:126-30. 2003....
- Prevalence of resistance to ampicillin, gentamicin and vancomycin in Enterococcus faecalis and Enterococcus faecium isolates from clinical specimens and use of antimicrobials in five Nordic hospitalsG S Simonsen
University of Tromsø and University Hospital of North Norway UNN, Norway
J Antimicrob Chemother 51:323-31. 2003We determined the species distribution and prevalence of ampicillin resistance, high-level gentamicin resistance (HLGR) and vancomycin resistance among clinical enterococcal isolates from five Nordic laboratories (Bergen, Tromsø, ..
- Beta-lactamase genes of the penicillin-susceptible Bacillus anthracis Sterne strainYahua Chen
Department of Microbiology and Molecular Genetics, The University of Texas Houston Health Science Center Medical School, 6431 Fannin Street, Houston, TX 77030, USA
J Bacteriol 185:823-30. 2003..cereus type II enzyme. The bla1 and bla2 genes confer ampicillin resistance to E. coli and Bacillus subtilis when cloned individually in these species...
- [Antimicrobial susceptibility of Streptococcus pneumoniae and Haemophilus influenzae isolated in major hospitals in Nagano Prefecture]Yoshitaka Yamazaki
Department of Endoscopy, Shinshu University Hospital
Jpn J Antibiot 55:524-36. 2002..The isolation rates of resistant strains were lower than those reported in a nationwide survey...
- Inhibition, resistance development, and increased antibiotic and antimicrobial resistance caused by nutraceuticalsPaulaMarieL Ward
Department of Biochemistry and Microbiology, Cook College, New Jersey Agricultural Experiment Station, Rutgers The State University of New Jersey, New Brunswick 08901 8525, USA
J Food Prot 65:528-33. 2002..coli ATCC 25922 as the indicator organism, the greatest product-antibiotic marker interaction was with the ampicillin marker. Garlic, Echinacea, and zinc products all caused large increases in the MIC to ampicillin over baseline values...
- [Surveillance for antimicrobial resistance: VIRA Study]Juan J Picazo
Servicio de Microbiología Clínica Hospital Clínico San Carlos Madrid España
Enferm Infecc Microbiol Clin 20:503-10. 2002..The aim of this multicenter study was to determine the current situation in Spain regarding the resistance patterns of the most common infectious agents to antimicrobial drugs...
- Antimicrobial resistance among invasive Haemophilus influenzae strains: results of a Brazilian study carried out from 1996 through 2000S T Casagrande
Departamento de Bacteriologia, Instituto Adolfo Lutz, Sao Paulo, SP, Brasil
Braz J Med Biol Res 35:1293-300. 2002..6 to 57.7%, with an overall prevalence of 18.4%. High frequency of beta-lactamase-mediated ampicillin resistance was observed in Distrito Federal (25%), São Paulo (21.7%) and Paraná (18.5%)...
- Antibiotic resistance of enterococci isolated at a teaching hospital in KuwaitE E Udo
Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
Diagn Microbiol Infect Dis 43:233-8. 2002..The results demonstrated a low prevalence of vancomycin resistance among Enterococci in this hospital...
- Detection of antimicrobial resistance and extended-spectrum beta-lactamase production in Klebsiella pneumoniae strains from infected neonatesE Aktas
Faculty of Medicine, Department of Microbiology and Clinical Microbiology, Ataturk University, Erzurum, Turkey
J Int Med Res 30:445-8. 2002....
- Diversity of ampicillin-resistance genes in Haemophilus influenzae in Japan and the United StatesKeiko Hasegawa
Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, Tokyo, 108 8641, Japan
Microb Drug Resist 9:39-46. 2003..Differences in proportions of respective AMP-resistant genes in H. influenzae isolates between the two countries might reflect differences in antibiotic agents ordinarily given to outpatients with community-acquired bacterial infections...
- Differentiation of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae from other H. influenzae strains by a disc methodKimiko Ubukata
Center for Epideniology and Clinical Microbiology, Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd, 760 Morookacho, Kohoku Ku, Yokohama 222 8567, Japan
J Infect Chemother 8:50-8. 2002....
- [Standardization of the Neisseria meningitidis antibiogram. Detection of strains relatively resistant to penicillin]P Nicolas
Bull World Health Organ 76:393-400. 1998..Based on our results and literature data on pharmacokinetics, we propose critical concentrations for these various antibiotics as well as critical diameters for chloramphenicol and rifampicin discs...
- Mutants carrying conditionally lethal mutations in outer membrane genes omsA and firA (ssc) are phenotypically similar, and omsA is allelic to firAR Vuorio
Department of Bacteriology and Immunology, University of Helsinki, Finland
J Bacteriol 174:7090-7. 1992..All of these findings are consistent with our concept that firA is an essential gene involved in generation of the outer membrane...
- Molecular characterization of ampicillin-resistant Enterococcus faecium isolates from hospitalized patients in NorwayRoland Jureen
Institute of Medicine, University of Bergen, Bergen, Norway
J Clin Microbiol 41:2330-6. 2003..protein 5 gene (pbp5) was determined, and sequence differences were associated with the level of ampicillin resistance. This study indicates that the majority of ampicillin-resistant E...
- A secondary drug resistance mutation of TEM-1 beta-lactamase that suppresses misfolding and aggregationV Sideraki
Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Proc Natl Acad Sci U S A 98:283-8. 2001..Thus, the M182T substitution is an example of a naturally occurring mutation that has evolved to alter the folding pathway of a protein and confer a selective advantage during the evolution of drug resistance...
- Molecular characterization of multidrug-resistant Salmonella enterica subsp. enterica serovar Typhimurium isolates from swineWondwossen Abebe Gebreyes
Department of Farm Animal Health Resources Management, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
J Clin Microbiol 40:2813-22. 2002..Two strains (strains UT08 and UT12) had a single, identical plasmid carrying bla(TEM) (which encodes ampicillin resistance), aphA1-Iab (which encodes kanamycin resistance), strA and strB (which encode streptomycin resistance), ..
- Antimicrobial activity of a novel peptide deformylase inhibitor, LBM415, tested against respiratory tract and cutaneous infection pathogens: a global surveillance report (2003-2004)Amy A Watters
JMI Laboratories, 345 Beaver Kreek Centre, Suite A, North Liberty, IA 52317, USA
J Antimicrob Chemother 57:914-23. 2006....
- Study of mechanisms of electric field-induced DNA transfection. I. DNA entry by surface binding and diffusion through membrane poresT D Xie
Department of Biochemistry, University of Minnesota College of Biological Sciences, St Paul 55108
Biophys J 58:13-9. 1990..pBR322 DNA carries an ampicillin resistance gene: E...
- Comparative study of Vibrio cholerae non-O1 isolated from 2 rivers according to antibiotics and metals susceptibilityH Uchiyama
Department of Public Health, School of Hygienic Sciences, Kitasato University
Kansenshogaku Zasshi 65:1541-9. 1991..2) 64.3% (74/115) of the strains isolated from the two rivers showed ampicillin resistance and produced beta-lactamase. 3) 67...
- Changes in antibiotic resistance rates of invasive Haemophilus influenzae isolates in England and Wales over the last 20 yearsShamez Ladhani
Immunisation Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
J Antimicrob Chemother 62:776-9. 2008..The aim of this study was to determine trends in antibiotic resistance profiles of invasive clinical Haemophilus influenzae isolates over the last 20 years...
- High ampicillin resistance in different biotypes and serotypes of Haemophilus influenzae colonizing the nasopharynx of healthy school-going Indian childrenAmita Jain
Department of Microbiology, King George s Medical University, Lucknow, UP, 226003, India
J Med Microbiol 55:133-7. 2006..of otitis media, sinusitis, meningitis, pneumonia and septicaemia in children, and the development of ampicillin resistance in H. influenzae is a cause of serious concern...
- Physical linkage of Tn3 and part of Tn1721 in a tetracycline and ampicillin resistance plasmid from Salmonella TyphimuriumFrédérique Pasquali
Department of Food Science, Alma Mater Studiorum, University of Bologna, via San Giacomo 9, 40126 Bologna, Italy
J Antimicrob Chemother 55:562-5. 2005..enterica serovar Typhimurium, which mediates resistance to tetracyclines and ampicillin, was determined. The plasmid was analysed for potential reading frames and structural features indicative of transposons and transposon relics...
- The presence of antibiotic resistance and integrons in Escherichia coli isolated from compostSpencer Heringa
Department of Food Science and Human Nutrition, Clemson University, Clemson, South Carolina 29634, USA
Foodborne Pathog Dis 7:1297-304. 2010..Resistance phenotypes comprised various combinations of seven antibiotics with a prevalence of ampicillin resistance in 63% of isolates (n = 56) from California, and tetracycline resistance in 37% of isolates (n = 62) from ..
- Apparent plateau in beta-lactamase production among clinical isolates of Haemophilus influenzae and Moraxella catarrhalis in the United States: results from the LIBRA Surveillance initiativeMark E Jones
Focus Technologies, Koninginneweg 11, 1217 KP, Hilversum, The Netherlands
Int J Antimicrob Agents 19:119-23. 2002..5 mg/l and < or =0.25 mg/l, respectively. beta-Lactamase production was found to confer ampicillin resistance in nearly all isolates. For M. catarrhalis, beta-lactamase-negative isolates had MICs < or =0.12-0...
- Antibiotic resistance in food-borne bacterial contaminants in VietnamThi Thu Hao Van
School of Applied Sciences, RMIT University, Building 3, Level 1, Room 2, City Campus, Melbourne, Victoria 3001, Australia
Appl Environ Microbiol 73:7906-11. 2007..gene cassettes dhfrXII, dfrA1, and dhfrA17 (trimethoprim resistance), the beta-lactamase gene bla(PSE1) (ampicillin resistance), and catB3 (chloramphenicol resistance)...
- Combination of altered PBPs and expression of cloned extended-spectrum beta-lactamases confers cefotaxime resistance in Haemophilus influenzaeBulent Bozdogan
Mikrobiyoloji ve Klinik Mikrobiyoloji, Adnan Menderes Universitesi Hastanesi, Aydin, Turkey
J Antimicrob Chemother 57:747-9. 2006..beta-Lactamase-negative ampicillin resistance (BLNAR) also occurs as a result of PBP3 modifications...
- Antibiotic resistance in Campylobacter jejuni and Campylobacter coli isolated from poultry in the South-East Queensland regionJeanette K Miflin
Department of Primary Industries and Fisheries, Animal Research Institute, Yeerongpilly, Queensland 4105, Australia
J Antimicrob Chemother 59:775-8. 2007..The aim of this study was to determine the antimicrobial resistance patterns of 125 Campylobacter jejuni and 27 Campylobacter coli isolates from 39 Queensland broiler farms...
- Occurrence of integrons and antimicrobial resistance genes among Salmonella enterica from BrazilGisele Peirano
Oswaldo Cruz Institute Avenida Brasil 4365, 21045 900 Rio de Janeiro, Brazil
J Antimicrob Chemother 58:305-9. 2006..To determine the occurrence of antimicrobial resistance genes and role of integrons among 135 antimicrobial-resistant Salmonella enterica from Brazil...
- POSITIVE SELECTION SYSTEMS USING MARKER GENESJohn Naleway; Fiscal Year: 2005..for administration to animal cells or bacteria that contain either the beta-galactosidase (lacZ) or ampicillin resistance (Beta-lactamase, amp) genes as gene fusion markers...
- Does ampicillin resistance or clade type determine GI colonization by E. faecium?KAVINDRA SINGH; Fiscal Year: 2013..We also found that pbp5 is a core gene that encodes, in HA-clade strains, PBP5-R (ampicillin resistance) and varies from PBP5-S (ampicillin MICs <4) of CA-clade isolates by ~5%...
- VIRULENCE IN COXIELLA BURNETTIIHERBERT THOMPSON; Fiscal Year: 1999..In aim 1, organisms will be transformed to ampicillin resistance using a mixture of plasmids en masse via electroporation. These plasmids carry the C...
- A Unified Reporter Gene for Multi-Modality ImagingJianghong Rao; Fiscal Year: 2005..An ampicillin resistance gene (encoding a bacterial enzyme, beta-lactamase) is an outstanding reporter for optical measurement of ..
- GENETIC STRATEGIES FOR DRUG TARGETINGJohn Naleway; Fiscal Year: 1999..for administration to animal cells or bacteria that contain either the beta- galactosidase (lac Z) or ampicillin resistance (beta-lactamase, amp) genes as gene fusion markers...
- In vivo regulation of M. tuberculosis cell wall lipidsLee W Riley; Fiscal Year: 2010..tuberculosis and granulomas may contribute to our understanding of the mechanism of persistence of M. tuberculosis that could lead to new tests to differentiate active TB from latent TB infection. ..
- Orgin of multidrug resistant uropathogenic E. coliLee Riley; Fiscal Year: 2008..This knowledge should lead to the implementation of improved control of drug-resistant infectious diseases. ..
- Therapeutic vaccine against tuberculosisLee Riley; Fiscal Year: 2006..Therapeutic vaccines against TB is a major priority in TB control, and we have an opportunity to identify such products by a novel approach using a simple, inexpensive, and reproducible animal model. ..
- Mechanisms of Tandem Repeat Deletion in Group B StrepKAREN PUOPOLO; Fiscal Year: 2006..The training goal of this project is to prepare the applicant for a career in bacterial genetic research by providing didactic education and the opportunity to develop laboratory expertise in this rapidly evolving field. ..
- ANTIOXIDANT GENES OF MYCOBACERIUM TUBERCULOSISLee Riley; Fiscal Year: 2001....
- Epidemiology of an uropathogenic E coli clonal groupLee Riley; Fiscal Year: 2003..coli can be spread by contaminated ingestible vehicles, and use the data generated from this project to design long-term studies to better characterize risk factors associated with CgA infection. ..
- MOLECULAR BIOLOGY OF INFECTION WITH M TUBERCULOSISLee Riley; Fiscal Year: 2002..In addition, these studies may identify several potential targets for new chemotherapeutic agents or vaccine candidates. ..
- FREE SOLUTION MOBILITY AS A PROBE OF DNA ELECTROSTATICSNancy Stellwagen; Fiscal Year: 2004..Further work entails an examination of the interaction between DNA and commonly used buffers in electrophoresis experiments. ..