herb drug interactions

Summary

Summary: The effect of herbs, other PLANTS, or PLANT EXTRACTS on the activity, metabolism, or toxicity of drugs.

Top Publications

  1. ncbi Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans
    Bill J Gurley
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, 72205, USA
    Clin Pharmacol Ther 72:276-87. 2002
  2. ncbi [Herbal medicines--evidence and drug interactions in clinical practice]
    Thomas Klint Kistorp
    Amtssygehuset i Gentofte, Anaestesiologisk afdeling, H S Frederiksberg Hospital, anaestesiklinikken
    Ugeskr Laeger 164:4161-5. 2002
  3. ncbi St John's wort: a systematic review of adverse effects and drug interactions for the consultation psychiatrist
    Paul Hammerness
    Harvard Medical School, Boston, Massachusetts, USA
    Psychosomatics 44:271-82. 2003
  4. ncbi Panax ginseng
    David Kiefer
    Program in Integrative Medicine, University of Arizona College of Medicine, Tucson, Arizona 85724, USA
    Am Fam Physician 68:1539-42. 2003
  5. ncbi Community identification of natural health product-drug interactions
    Theresa L Charrois
    CARE Program, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    Ann Pharmacother 41:1124-9. 2007
  6. ncbi Concise review: Clinical relevance of drug drug and herb drug interactions mediated by the ABC transporter ABCB1 (MDR1, P-glycoprotein)
    Serena Marchetti
    The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    Oncologist 12:927-41. 2007
  7. pmc St Johns wort increases expression of P-glycoprotein: implications for drug interactions
    Martina Hennessy
    Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, St James s Hospital, Trinity College, Dublin 8, Ireland, UK
    Br J Clin Pharmacol 53:75-82. 2002
  8. ncbi Potential interactions between alternative therapies and warfarin
    A M Heck
    School of Pharmacy and Pharmacal Sciences, Purdue University, Indianapolis, IN, USA
    Am J Health Syst Pharm 57:1221-7; quiz 1228-30. 2000
  9. pmc Effect of trikatu pretreatment on the pharmacokinetics of pefloxacin administered orally in mountain Gaddi goats
    Madhukar S Dama
    Department of Pharmacology and Toxicology, College of Veterinary and Animal Sciences, CSK Himachal Pradesh Agricultural University, Palampur 176 062, Himachal Pradesh, India
    J Vet Sci 9:25-9. 2008
  10. ncbi Pharmacokinetic and pharmacodynamic studies on interaction of "Trikatu" with diclofenac sodium
    L G Lala
    Department of Pharmacognosy and Phytochemistry, Prin K M Kundnani College of Pharmacy, Dr R G Thadani Marg, Worli, Mumbai 400 018, India
    J Ethnopharmacol 91:277-80. 2004

Detail Information

Publications224 found, 100 shown here

  1. ncbi Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans
    Bill J Gurley
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, 72205, USA
    Clin Pharmacol Ther 72:276-87. 2002
    ..Single-time point phenotypic metabolic ratios were used to determine whether long-term supplementation of St John's wort, garlic oil, Panax ginseng, and Ginkgo biloba affected CYP1A2, CYP2D6, CYP2E1, or CYP3A4 activity...
  2. ncbi [Herbal medicines--evidence and drug interactions in clinical practice]
    Thomas Klint Kistorp
    Amtssygehuset i Gentofte, Anaestesiologisk afdeling, H S Frederiksberg Hospital, anaestesiklinikken
    Ugeskr Laeger 164:4161-5. 2002
    ..Physicians should be aware of and report potential drug interactions and adverse effects, so as to throw more light on this subject...
  3. ncbi St John's wort: a systematic review of adverse effects and drug interactions for the consultation psychiatrist
    Paul Hammerness
    Harvard Medical School, Boston, Massachusetts, USA
    Psychosomatics 44:271-82. 2003
    ..This evidence-based presentation of the literature includes a brief description of pharmacodynamics and clinical applications, followed by a systematic review of adverse effects, toxicity, and drug interactions...
  4. ncbi Panax ginseng
    David Kiefer
    Program in Integrative Medicine, University of Arizona College of Medicine, Tucson, Arizona 85724, USA
    Am Fam Physician 68:1539-42. 2003
    ..Panax ginseng does not appear to enhance physical performance. Products with a standardized ginsenoside concentration are available...
  5. ncbi Community identification of natural health product-drug interactions
    Theresa L Charrois
    CARE Program, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    Ann Pharmacother 41:1124-9. 2007
    ..Community pharmacists regularly field inquiries regarding NHPs. As such, pharmacists are ideally placed to answer questions about NHP use and interactions with other medications...
  6. ncbi Concise review: Clinical relevance of drug drug and herb drug interactions mediated by the ABC transporter ABCB1 (MDR1, P-glycoprotein)
    Serena Marchetti
    The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    Oncologist 12:927-41. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  7. pmc St Johns wort increases expression of P-glycoprotein: implications for drug interactions
    Martina Hennessy
    Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, St James s Hospital, Trinity College, Dublin 8, Ireland, UK
    Br J Clin Pharmacol 53:75-82. 2002
    ....
  8. ncbi Potential interactions between alternative therapies and warfarin
    A M Heck
    School of Pharmacy and Pharmacal Sciences, Purdue University, Indianapolis, IN, USA
    Am J Health Syst Pharm 57:1221-7; quiz 1228-30. 2000
    ..Pharmacists and other health care professionals should question all patients about use of alternative therapies and report documented interactions to FDA's MedWatch program...
  9. pmc Effect of trikatu pretreatment on the pharmacokinetics of pefloxacin administered orally in mountain Gaddi goats
    Madhukar S Dama
    Department of Pharmacology and Toxicology, College of Veterinary and Animal Sciences, CSK Himachal Pradesh Agricultural University, Palampur 176 062, Himachal Pradesh, India
    J Vet Sci 9:25-9. 2008
    ..21 mg/kg is required to be administered at 8 h intervals. For practical purposes in goats this would mean a priming dose of 6 mg/kg and a maintenance dose of 2 mg/kg given by the oral route, to be repeated at 8 h intervals...
  10. ncbi Pharmacokinetic and pharmacodynamic studies on interaction of "Trikatu" with diclofenac sodium
    L G Lala
    Department of Pharmacognosy and Phytochemistry, Prin K M Kundnani College of Pharmacy, Dr R G Thadani Marg, Worli, Mumbai 400 018, India
    J Ethnopharmacol 91:277-80. 2004
    ..Thus, the experimental findings indicated that Trikatu pretreatment might decrease the bioavailability of certain drugs probably through a drug-herb interaction thereby adversely affecting the therapeutic efficacy of these drugs...
  11. ncbi Interactions between herbal medicines and prescribed drugs: a systematic review
    A A Izzo
    Department of Experimental Pharmacology, University of Naples 'Federico II, Naples, Italy
    Drugs 61:2163-75. 2001
    ..Healthcare professionals should ask their patients about the use of herbal products and consider the possibility of herb-drug interactions...
  12. ncbi Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens
    M Singh
    Department of Pharmacology and Toxicology, College of Veterinary and Animal Sciences, CSK Himachal Pradesh Agricultural University, Himachal Pradesh, India
    J Vet Sci 6:197-200. 2005
    ..The total body clearance (Cl(B)) reduced by 21%whereas total duration of pharmacological effect (t(d)) increased by 29%. The treatment with P. longum reduced loading and maintenance dose by 33.3 and 39%, respectively...
  13. ncbi Perioperative herbal supplement use in cancer patients: potential implications and recommendations for presurgical screening
    Nagi B Kumar
    Department of Nutrition, H Lee Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, Tampa, Florida 33612, USA
    Cancer Control 12:149-57. 2005
    ..The use of herbal supplements by cancer patients in the perioperative period is common and consistent with the substantial increase in the use of alternative medical therapies...
  14. pmc St John's wort (Hypericum perforatum): drug interactions and clinical outcomes
    L Henderson
    Pharmacovigilance Group, Medicines Control Agency, UK
    Br J Clin Pharmacol 54:349-56. 2002
    ..The aim of this work is to identify the medicines which interact with the herbal remedy St John's wort (SJW), and the mechanisms responsible...
  15. ncbi Herbal hepatotoxicity
    Leonard B Seeff
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 31 Center Drive, Room 9A27, Bethesda, MD 20892, USA
    Clin Liver Dis 11:577-96, vii. 2007
    ..Although many of them are clearly implicated, there are some, particularly those identified solely through an occasional case report, for which the relationship is uncertain...
  16. ncbi An examination of the bleeding complications associated with herbal supplements, antiplatelet and anticoagulant medications
    A E Spolarich
    Arizona School of Dentistry and Oral Health, USA
    J Dent Hyg 81:67. 2007
    ....
  17. ncbi Lack of pharmacokinetic interaction between St. John's wort and prednisone
    Edward C Bell
    College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA
    Ann Pharmacother 41:1819-24. 2007
    ..The supplement has been shown to affect the metabolism of various CYP3A4 substrates. The CYP3A4 pathway mediates the metabolism of a large number of drug entities, including the corticosteroids prednisone and prednisolone...
  18. ncbi Herbal medicine and epilepsy: proconvulsive effects and interactions with antiepileptic drugs
    Noah Samuels
    The Center for Integrative Complementary Medicine, Shaare Zadek Medical Center, Jerusalem, Israel
    Epilepsia 49:373-80. 2008
    ..At the same time, further research is required regarding the effect of herbs on seizure activity and interactions with AED treatment...
  19. pmc Potential interactions between complementary/alternative products and conventional medicines in a Medicare population
    Gary W Elmer
    Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA
    Ann Pharmacother 41:1617-24. 2007
    ..Despite the high prevalence of complementary and alternative medicine (CAM) product use among the elderly, little is known about the extent of concurrent CAM-conventional medicine use and the potential for adverse reactions...
  20. ncbi Herbal supplements in older adults. Consider interactions and adverse events that may result from supplement use
    Jennifer C Hoblyn
    Palo Alto Veterans Affairs Health Care System, California, USA
    Geriatrics 60:18, 22-3. 2005
  21. ncbi Pharmacokinetic interactions of drugs with St John's wort
    Shufeng Zhou
    Department of Pharmacy, Faculty of Science, National University of Singapore
    J Psychopharmacol 18:262-76. 2004
    ..Because the potential interaction of St John's wort with other drugs is a major safety concern, additional systematic research on herb-drug interactions and appropriate regulation in herbal safety and efficacy is needed...
  22. ncbi Herbal supplements and therapeutic drug monitoring: focus on digoxin immunoassays and interactions with St. John's wort
    Amitava Dasgupta
    Department of Pathology and Laboratory Medicine, University of Texas Health Sciences Center at Houston, Houston, Texas, USA
    Ther Drug Monit 30:212-7. 2008
    ..John's wort. Understanding the effect of herbal products on TDM methodologies and identification of interactions between herbal products and drugs by TDM are very important clinically...
  23. ncbi Complementary and alternative interventions in asthma, allergy, and immunology
    Leonard Bielory
    Department of Medicine, Pediatrics, and Ophthalmology, Division of Allergy, Immunology, and Rheumatology, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    Ann Allergy Asthma Immunol 93:S45-54. 2004
    ..To review which herbs are most commonly used as complementary and alternative medicine (CAM) for treatment of asthma, allergy, and immunologic conditions...
  24. ncbi Herbal medications in the perioperative orthopedic surgery patient
    Philip Trapskin
    University of Kentucky Chandler Medical Center, Lexington, KY 40536, USA
    Orthopedics 27:819-22. 2004
  25. ncbi Pharmacokinetic herb-drug interactions: are preventive screenings necessary and appropriate?
    Veronika Butterweck
    Department of Pharmaceutics, University of Florida, Gainesville, FL, USA
    Planta Med 70:784-91. 2004
    ..Efforts to identify all possible interactions will lead to limitless investigations and to inconsistent decisions...
  26. ncbi The case of the felonious foxglove: the dark side of natural cures
    Marjorie K Jeffcoat
    J Am Dent Assoc 135:1218, 1220. 2004
  27. ncbi [Potential risks, adverse effects and drug interactions associated with herbal medicine in dental patients]
    A Zlotogorski Hurvitz
    Dept of Oral Pathology and Oral Medicine, The Maurice and Gabriela Goldschlager School of Dental Medicine, Tel Aviv University, Tel Aviv
    Refuat Hapeh Vehashinayim 21:25-41, 97. 2004
    ..The purpose of this article was to review the literature on the potential risks of commonly used herbal medications: Ginkgo Biloba, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, Garlic, Kava and Ephedra...
  28. ncbi The effect of herbal medicines on platelet function: an in vivo experiment and review of the literature
    Benjamin W Beckert
    Division of Plastic Surgery and Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, MO 65201, USA
    Plast Reconstr Surg 120:2044-50. 2007
    ....
  29. ncbi Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interaction
    Angelo A Izzo
    Department of Experimental Pharmacology, University of Naples Federico II, via D Montesano 49, 80131 Naples, Italy
    Int J Cardiol 98:1-14. 2005
    ..John's wort. Interaction between herbal medicine and cardiovascular drugs is a potentially important safety issue. Patients taking anticoagulants are at the highest risk...
  30. pmc Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba
    Bill J Gurley
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Drugs Aging 22:525-39. 2005
    ....
  31. ncbi Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis
    Stephen Shalansky
    Pharmacy Department, Vancouver Coastal Health Providence Health Care Pharmacy Services, Vancouver, British Columbia, Canada
    Pharmacotherapy 27:1237-47. 2007
    ..To determine the risk of bleeding and supratherapeutic international normalized ratios (INRs) associated with use of complementary and alternative medicine (CAM) in patients receiving warfarin...
  32. ncbi Safety of St. John's Wort extract compared to synthetic antidepressants
    V Schulz
    Phytomedicine 13:199-204. 2006
    ..However, such cases are extremely rare and, with medical supervision, easily avoided. In conclusion, the safety of SWE must be considered more favourable than that of synthetic antidepressants...
  33. ncbi Herbs and dietary supplement use in patients with stage 5 chronic kidney disease
    Jerrilynn D Burrowes
    Long Island University, Department of Nutrition, School of Health Professions and Nursing, Brookville, NY, USA
    Nephrol Nurs J 33:85-8. 2006
    ..Information on the use, safety, efficacy, adverse effects, and recommended dosages in the nondialysis population are summarized in this article...
  34. ncbi Use of herbal supplements and vitamins in plastic surgery: a practical review
    George Broughton
    Department of Plastic Surgery, Nancy L and Perry Bass Advanced Wound Healing Laboratory, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9132, USA
    Plast Reconstr Surg 119:48e-66e. 2007
    ..4. Explain the preoperative management of patients using herbal supplements. 5. Know additional resources to consult when unanswered questions arise...
  35. pmc Herbal product-drug interactions mediated by induction
    Rommel G Tirona
    Division of Clinical Pharmacology, Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Br J Clin Pharmacol 61:677-81. 2006
    ..This type of interaction is likely to be relevant to other herbal products. Caregivers need to be aware of the issues and options for therapeutic management...
  36. ncbi Hypericum perforatum: which constituents may induce intestinal MDR1 and CYP3A4 mRNA expression?
    Heike Gutmann
    Department of Clinical Pharmacology and Toxicology, University Clinic Basel, Basel, Switzerland
    Planta Med 72:685-90. 2006
    ..These effects could be mimicked by "artificial extracts" containing the same compositions of hyperforin, hypericin and quercitrin as the plant extracts...
  37. ncbi [Anaesthetic preoperative assessment of chronic medications and herbal medicine use: a multicenter survey]
    C Baillard
    Départements d anesthésie réanimation, CHU Avicenne, EA 3409, 93009 Bobigny, France
    Ann Fr Anesth Reanim 26:132-5. 2007
    ..This study was undertaken to quantify the use of chronic medication and herbal remedies in the presurgical population...
  38. ncbi Herbal supplements: Facts and myths--talking to your patients about herbal supplements
    Barbara Ann M Messina
    School of Nursing, State University of New York at Stony Brook, Stony Brook, NY 11794 8240, USA
    J Perianesth Nurs 21:268-78; quiz 279-81. 2006
    ....
  39. ncbi Effects of Hypericum perforatum on ivabradine pharmacokinetics in healthy volunteers: an open-label, pharmacokinetic interaction clinical trial
    A Portoles
    Clinical Pharmacology Studies Unit, Clinical Pharmacology Service, Hospital Clinico San Carlos, Madrid, Spain
    J Clin Pharmacol 46:1188-94. 2006
    ..3 +/- 25.1 ng x h/mL, P < .01). Tendencies toward shorter time to C(max) and lower apparent terminal half-life values were found. Pharmacokinetic results are consistent with an induction of ivabradine metabolism by H perforatum...
  40. ncbi Unregulated herbal products: potential interactions and side effects in dental patients
    Roger E Alexander
    Department of Oral and Maxillofacial Surgery, Baylor College of Dentistry, Texas A and M University Health Science Center, Dallas, USA
    Tex Dent J 124:364-85. 2007
  41. ncbi Evolution of medical treatment for endometriosis: back to the roots?
    Fritz Wieser
    Division of Gynecological Endocrinology and Reproductive Medicine, University of Vienna, 1090 Vienna, Austria
    Hum Reprod Update 13:487-99. 2007
    ..We encourage the development of herbal analogues and establishment of special, simplified registration procedures for certain medicinal products, particularly herbal derivates with a long tradition of safe use...
  42. ncbi Interaction between a commercially available St. John's wort product (Movina) and atorvastatin in patients with hypercholesterolemia
    L Andrén
    Department of Medicine Clinical Pharmacology, Gothenburg University, Sahlgrenska University Hospital, Vita Stråket 11, S 413 45, Gothenburg, Sweden
    Eur J Clin Pharmacol 63:913-6. 2007
    ....
  43. ncbi Prediction of herb-drug metabolic interactions: a simulation study
    Shufeng Zhou
    Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore
    Phytother Res 19:464-71. 2005
    ..However, many herb- and drug-related factors may cause difficulties with the prediction, and thus in vivo animal and human studies are always necessary...
  44. ncbi An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constituents
    Amy S Etheridge
    Health Sciences Unit, Science and Engineering, RTI International, Research Triangle Park, NC 27709 2194, USA
    Planta Med 73:731-41. 2007
    ..The data suggest that the clearance of a variety of drugs may be diminished by concomitant use of these herbs via inhibition of P450 enzymes, but less so by Pgp-mediated effects...
  45. ncbi Herb digoxin interactions
    Tsung O Cheng
    Int J Cardiol 110:93. 2006
  46. ncbi Ginseng and other herbal medicines that interact with warfarin
    Tsung O Cheng
    Int J Cardiol 104:227. 2005
  47. ncbi Natural health product-drug interactions: a systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ther Drug Monit 27:549-57. 2005
    ..With the exception of St. John wort, clinicians and the public do not have information that permits strong inferences about interactions between NHPs and conventional medications...
  48. ncbi Complementary and alternative medicine (CAM) for the treatment of chronic hepatitis B and C: a review
    Apurva A Modi
    The National Institute of Diabetes and Digestive and Kidney Diseases, The National Institute of Health, Bethesda, MD, USA
    Antivir Ther 12:285-95. 2007
    ..Five herbals used in the past to treat viral hepatitis are reviewed and evaluated for the quality of their studies and mention is made of herbals known to have adverse effects...
  49. ncbi [Natural remedies--self care at your own risk! Danger of unknown adverse effects and interactions with "common" medications]
    Curt Peterson
    Universitetssjukhuset i Linköping
    Lakartidningen 102:3200-1. 2005
  50. ncbi Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach
    Xuemin Jiang
    Faculty of Pharmacy, The University of Sydney, NSW 2006, Australia
    J Clin Pharmacol 46:1370-8. 2006
    ..None of the herbs studied had a direct effect on warfarin pharmacodynamics. Studies in anticoagulated patients are warranted to assess the clinical significance of these herb-drug interactions...
  51. ncbi [Adverse drug effects and interactions. What is the current thinking about the use of St. John's wort?]
    Andreas Johne
    Institut für Klinische Pharmakologie Universitätsklinikum Charité Humboldt Universität zu Berlin Schumannstr, 20 21 D 10098 Berlin
    Pharm Unserer Zeit 32:242-6. 2003
  52. ncbi Toward optimal health: the experts discuss the use of botanicals by women. Interview by Jody Godfrey Meisler
    Stacie E Geller
    National Center of Excellence in Women s Health, University of Illinois, Chicago, IL, USA
    J Womens Health (Larchmt) 12:847-52. 2003
  53. ncbi [Drug interactions caused by phytopharmaceuticals. Don't underestimate herbs!]
    Peter Stiefelhagen
    MMW Fortschr Med 144:6-9. 2002
  54. ncbi Potential drug-herb interaction with antiplatelet/anticoagulant drugs
    Jun Tze Saw
    School of Pharmaceutical Sciences, University Science Malaysia, Minden, 11800 Penang, Malaysia
    Complement Ther Clin Pract 12:236-41. 2006
    ..It is thus prudent for all care givers to be aware of the possibility of drug-herb interaction and inquire about herbal use from patients...
  55. ncbi The use of herbs and complementary and alternative medicine in pediatric preoperative patients
    Yuan Chi Lin
    Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    J Clin Anesth 16:4-6. 2004
    ..To determine the use of herbs and complementary and alternative medicine among a pediatric preoperative population...
  56. ncbi Herbal therapies
    Robert H Howland
    University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    J Psychosoc Nurs Ment Health Serv 43:16-9. 2005
  57. ncbi Herbal medication: potential for adverse interactions with analgesic drugs
    W Abebe
    Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GA 30912 1128, USA
    J Clin Pharm Ther 27:391-401. 2002
    ..However, as most of the interaction information available is based on individual case reports, animal studies and in vitro data, further research is needed to confirm and assess the clinical significance of these potential interactions...
  58. ncbi Herbal interactions with cardiovascular drugs
    Dennis V C Awang
    MediPlant Consulting Inc, White Rock, British Columbia, Canada
    J Cardiovasc Nurs 16:64-70. 2002
    ..This can be especially important for drugs with narrow therapeutic windows and in sensitive patient populations such as older adults, the chronically ill, and those with compromised immune systems...
  59. ncbi Herb-drug interactions
    Lisa Cranwell-Bruce
    Byridine F Lewis School of Nursing, College of Health and Human Services, Georgia State University, Atlanta, GA, USA
    Medsurg Nurs 17:52-4. 2008
  60. ncbi The emerging recognition of herb-drug interactions with a focus on St. John's wort (Hypericum perforatum)
    J S Markowitz
    Department of Pharmaceutical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC, USA
    Psychopharmacol Bull 35:53-64. 2001
    ..Concomitant use of herbal agents and conventional medications should generally be discouraged until further information is available. Additional research is urgently needed in this area...
  61. ncbi [Metabolic effects and drug interactions provoked by certain vegetables: grapefruit, St. John's wort and garlic]
    Maur Neuman
    Presse Med 31:1416-22. 2002
    ..GARLIC: (Allium salivum) Originating from Asia, widespread and cultivated in Europe in kitchen gardens, garlic is used by herbalists for its diuretic, antiseptic, stimulating and sudorific properties...
  62. ncbi Herbal extracts used for upper respiratory tract infections: are there clinically relevant interactions with the cytochrome P450 enzyme system?
    Michael Heinrich
    Centre for Pharmacognosy and Phytotherapy, The School of Pharmacy, University of London, London, United Kingdom
    Planta Med 74:657-60. 2008
    ..The available evidence points to weak cytochrome P450 inhibition which is unlikely to be of clinical relevance...
  63. ncbi Drug interactions with St. John's Wort (Hypericum perforatum): a review of the clinical evidence
    A A Izzo
    Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
    Int J Clin Pharmacol Ther 42:139-48. 2004
    ..g. sertaline, paroxetine, nefazodone) or buspirone, SJW can cause serotonergic syndrome. SJW represents a herbal medicine with a high potential for drug interactions. Some of such interactions may have serious clinical consequences...
  64. ncbi Herb-drug interactions
    A Fugh-Berman
    George Washington University School of Medicine and Health Sciences, Department of Health Care Sciences, Washington, DC 20037, USA
    Lancet 355:134-8. 2000
    ..Many reports of herb-drug interactions are sketchy and lack laboratory analysis of suspect preparations. Health-care practitioners should caution patients against mixing herbs and pharmaceutical drugs...
  65. ncbi Metabolic activation of herbal and dietary constituents and its clinical and toxicological implications: an update
    Shu Feng Zhou
    Division of Pharmacy, School of Life Sciences, Faculty of Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Curr Drug Metab 8:526-53. 2007
    ..Due to the wide use and easy availability of herbal medicines, further research should be conducted to ensure the safety and quality of herbal medicine...
  66. ncbi Herbal medicines and perioperative care
    M K Ang-Lee
    Department of Anesthesia and Critical Care, University of Chicago, 5841 S Maryland Ave, MC 4028, Chicago, IL 60637, USA
    JAMA 286:208-16. 2001
    ..Widespread use of herbal medications among the presurgical population may have a negative impact on perioperative patient care...
  67. ncbi A review of the use of CAM therapy and the sources of accurate and reliable information
    Mary McHughes
    Department of Pharmacotherapy, College of Pharmacy, University of Utah, 30 South 2000 East Rm 258, Salt Lake City, UT 84112 5820, USA
    J Manag Care Pharm 11:695-703. 2005
    ....
  68. ncbi [Use of complementary and alternative medicine among the patients in primary health care]
    Tomislav Cizmesija
    National Railroad Health Center, University of Zagreb, Zagreb, Croatia
    Acta Med Croatica 62:15-22. 2008
    ..Use of complementary and alternative medicine (CAM) is widespread in western countries despite its unconfirmed effectiveness. The aim of the study was to show the use of CAM by patients in primary health care...
  69. ncbi Herbal bioactivation: the good, the bad and the ugly
    Shufeng Zhou
    Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, 117543
    Life Sci 74:935-68. 2004
    ..The safety and quality of herbal medicine should be ensured through greater research, pharmacovigilance, greater regulatory control and better communication between patients and health professionals...
  70. ncbi Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro
    Xin Wang
    School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
    Phytomedicine 17:868-75. 2010
    ....
  71. ncbi [Oral anticoagulants: a literature review of herb-drug interactions or food-drug interactions]
    S Bourget
    Département pharmacie, Centre Hospitalier Universitaire de Grenoble, Grenoble, France
    J Pharm Belg 62:69-75. 2007
    ..To identify herbal medicines and food products which can interact with anticoagulant therapy...
  72. ncbi Impact of traditional medicinal plant extracts on antiretroviral drug absorption
    L Brown
    Department of Pharmacy, University of Limpopo Medunsa Campus, P O Box 218, Ga Rankuwa 0204, South Africa
    J Ethnopharmacol 119:588-92. 2008
    ..Many patients infected with the human immunodeficiency virus are taking traditional herbal medicines in conjunction with their modern antiretroviral medication and drug-herb interactions can occur in these cases...
  73. ncbi Some commonly fed herbs and other functional foods in equine nutrition: a review
    Carey A Williams
    Department of Animal Sciences, Equine Science Center, Rutgers, The State University of New Jersey, School of Environmental and Biological Sciences, New Brunswick, NJ 08901, USA
    Vet J 178:21-31. 2008
    ..Horses fed garlic at >0.2g/kg per day developed Heinz body anaemia. Drug-herb interactions are common and caution needs to be taken when implementing 'natural product' usage...
  74. pmc A gap between acceptance and knowledge of herbal remedies by physicians: the need for educational intervention
    Yuri N Clement
    Faculty of Medical Sciences, The University of the West Indies, Trinidad and Tobago
    BMC Complement Altern Med 5:20. 2005
    ....
  75. ncbi Plant polyphenol curcumin significantly affects CYP1A2 and CYP2A6 activity in healthy, male Chinese volunteers
    Yao Chen
    Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, China
    Ann Pharmacother 44:1038-45. 2010
    ..Curcumin is a kind of plant polyphenol that is extracted from the rhizome of Curcuma longa. Studies about the effect of curcumin on the activity of drug-metabolizing enzymes in humans are lacking...
  76. ncbi 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions
    Jingwei Zhang
    Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, Jiangsu, 210009, People s Republic of China
    Drug Metab Dispos 38:2179-87. 2010
    ..It could increase the absorption of P-gp substrate drugs without long-term induction of P-gp expression in rats...
  77. ncbi Cardiovascular adverse effects of herbal medicines: a systematic review of the recent literature
    E Ernst
    Complementary Medicine, Peninsula Medical School, University of Exeter, Devon, United Kingdom
    Can J Cardiol 19:818-27. 2003
    ..In conclusion, herbal medicinal products are regularly associated with serious cardiovascular adverse events but the size of this problem cannot be estimated at present. Vigilance and research seem to be the best way forward...
  78. ncbi Intra-herb pharmacokinetics interaction between quercetin and isorhamentin
    Ke Lan
    Key Laboratory of Drug Targeting and Novel Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu 610041, China
    Acta Pharmacol Sin 29:1376-82. 2008
    ..The intra-herb pharmacokinetics interactions between isorhamnetin and quercetin were investigated in the present study...
  79. ncbi Effects of kava alkaloid, pipermethystine, and kavalactones on oxidative stress and cytochrome P450 in F-344 rats
    Steven T S Lim
    Laboratory of Metabolic Disorders and Alternative Medicine, Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA
    Toxicol Sci 97:214-21. 2007
    ....
  80. ncbi Effects of Evodia rutaecarpa and rutaecarpine on the pharmacokinetics of caffeine in rats
    Tung Hu Tsai
    National Research Institute of Chinese Medicine, Taipei, Taiwan
    Planta Med 71:640-5. 2005
    ..This finding should be very important whenever herb-drug interactions would be possible for a herbal remedy...
  81. ncbi In vitro effects of Mangifera indica and polyphenols derived on ABCB1/P-glycoprotein activity
    Elisabetta Chieli
    Dipartimento di Patologia Sperimentale, Universita degli Studi di Pisa, Via Roma 55, 56126 Pisa, Italy
    Food Chem Toxicol 47:2703-10. 2009
    ..Our results demonstrate, for the first time, that M. indica and polyphenols derived may affect the activity of the multidrug transporter P-gp ABCB1, suggesting the possibility of herb-drug interactions to be explored in depth...
  82. pmc Fukinolic acid derivatives and triterpene glycosides from black cohosh inhibit CYP isozymes, but are not cytotoxic to Hep-G2 cells in vitro
    Yue Huang
    Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, 833 S Wood St, Chicago, IL 60612, USA
    Curr Drug Saf 5:118-24. 2010
    ....
  83. ncbi Complementary and alternative approaches to the treatment of persistent musculoskeletal pain
    Debra K Weiner
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 3313, USA
    Clin J Pain 20:244-55. 2004
    ..To review common complementary and alternative treatment modalities for the treatment of persistent musculoskeletal pain in older adults...
  84. ncbi Prescription pattern of traditional Chinese medicine for climacteric women in Taiwan
    Y H Yang
    Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taipei
    Climacteric 12:541-7. 2009
    ..Traditional Chinese medicine (TCM) has become more popular as a therapy for symptom relief among menopause-aged women. The aim of this study was to analyze the utilization of TCM for climacteric women in Taiwan...
  85. ncbi Herb-drug interactions: in vivo and in vitro effect of Shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in rats
    Chun Hua Xia
    Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
    Planta Med 76:245-50. 2010
    ..9 %, respectively. These in vivo and in vitro results demonstrated that SMI had the potential to inhibit the activities of hepatic CYP3A1/2 and CYP2C6, but might not significantly affect CYP1A2 and CYP2E1-mediated metabolism in rats...
  86. pmc Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations
    Francesca Borrelli
    Department of Experimental Pharmacology, University of Naples Federico II, via D Montesano 49, 80131, Naples, Italy
    AAPS J 11:710-27. 2009
    ..e., irinotecan, imatinib) drugs. Hyperforin, which is believed to contribute to the antidepressant action of St John's wort, is also strongly suspected to be responsible of most of the described interactions...
  87. ncbi St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature
    J M Greeson
    Center for Integrative Medicine, Thomas Jefferson University Hospital, Jefferson Medical College, Philadelphia, PA 19107 6799, USA
    Psychopharmacology (Berl) 153:402-14. 2001
    ..Given the current widespread use of this herbal remedy, it is important for medical professionals to understand the potential pharmacological pathways through which Hypericum may exert an antidepressant effect...
  88. pmc 'They don't ask me so I don't tell them': patient-clinician communication about traditional, complementary, and alternative medicine
    Brian M Shelley
    First Choice Community Healthcare, Albuquerque, New Mexico 87105, USA
    Ann Fam Med 7:139-47. 2009
    ..Such communication can be important in anticipating possible drug-herb interactions and in assuring agreement about therapeutic plans...
  89. ncbi Effect of Danggui and Honghua on Cytochrome P450 1A2, 2C11, 2E1 and 3A1 mRNA Expression in Liver of Rats
    Yan Hong Li
    Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510406, China
    Am J Chin Med 36:1071-81. 2008
    ..Therefore, patients should be cautioned about the potential drug-herb interactions between Danggui or Honghua and prescription drugs that were metabolized by CYP1A2, 2E1 and 3A1 isoforms...
  90. ncbi The effect of standardized Echinacea purpurea extract on rat cytochrome P450 expression level
    P M Mrozikiewicz
    Laboratory of Experimental Pharmacogenetics, Department of Clinical Pharmacy and Biopharmacy, University of Medical Sciences, Poznan, Poland
    Phytomedicine 17:830-3. 2010
    ..These findings suggest that Echinacea extract may influence the P450-mediated metabolism of different drugs and may initiate chemical carcinogenesis by activation of some compounds to their carcinogenic metabolites...
  91. ncbi South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides--a review
    E Joubert
    Post Harvest and Wine Technology Division, ARC Infruitec Nietvoorbij, Private Bag X5026, Stellenbosch 7599, South Africa
    J Ethnopharmacol 119:376-412. 2008
    ....
  92. ncbi Physician knowledge of herbal toxicities and adverse herb-drug interactions
    Jeffrey R Suchard
    Department of Emergency Medicine, University of California Irvine Medical Center, Orange, CA, USA
    Eur J Emerg Med 11:193-7. 2004
    ..To determine how knowledgeable physicians are regarding the toxic effects and drug interactions of herbal remedies...
  93. ncbi Dietary supplements for the prevention and treatment of coronary artery disease
    Jeffrey Knox
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Altern Complement Med 13:83-95. 2007
    ..We set out to systematically review the dietary supplements available for the prevention and treatment of coronary artery disease...
  94. ncbi Herbal medicine use in parturients
    David L Hepner
    Department of Anaesthesia, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Anesth Analg 94:690-3; table of contents. 2002
    ..6% of parturients) were the most likely to use herbal remedies (17.1% rate of use in this age group). Many parturients who took herbal remedies (46%) did so on the recommendation of their health care provider...
  95. ncbi Sho-saiko-to and Saiko-keisi-to, the traditional Chinese and Japanese herbal medicines, altered hepatic drug-metabolizing enzymes in mice and rats when administered orally for a long time
    Mitsuhiko Nose
    Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    J Pharm Pharmacol 55:1419-26. 2003
    ..Sho-saiko-to and Saiko-keishi-to may potentially influence the drug-metabolizing enzymes in man, and would thus require much attention when used in the clinical situation...
  96. ncbi High use of complementary therapies in a New South Wales rural community
    J M Wilkinson
    School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia
    Aust J Rural Health 9:166-71. 2001
    ..Furthermore, these professionals should be alert to the potential for increased numbers of herb-drug interactions in rural communities...
  97. ncbi Use of traditional Chinese medicine in Singapore children: perceptions of parents and paediatricians
    C H Loh
    Medical School, Brookfield Health Sciences Complex, University College Cork, College Road, Cork, Ireland
    Singapore Med J 50:1162-8. 2009
    ..These are assessed in another arm of this study, with a set of predictive characteristics for their personal TCM use, their perceptions of herb/acupuncture safety, and their own referral to TCM eventually determined...
  98. ncbi Herbal medicine and cancer: an introductory overview
    Jonathan Treasure
    Centre for Natural Healing, Ashland, OR 97520, USA
    Semin Oncol Nurs 21:177-83. 2005
    ....
  99. ncbi Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure
    Mehmet Horoz
    Department of Internal Medicine, Division of Nephrology, Mersin Universitiy, School of Medicine, Mersin, Turkey
    Intern Med 47:2039-42. 2008
    ..We report a case of multisystem hypersensitivity reaction and progressive acute renal failure associated with the consumption of Crataegus orientalis...
  100. ncbi Herbal remedies for menopausal symptoms: are we cautious enough?
    Ronit Haimov-Kochman
    Division of Obstetrics and Gynaecology, Hadassah Hebrew University Hospital, Jerusalem, Israel
    Eur J Contracept Reprod Health Care 13:133-7. 2008
    ..To evaluate adverse effects of herbal remedies consumed by menopausal women for control of the climacteric syndrome...
  101. ncbi Emerging significance of P-glycoprotein in understanding drug disposition and drug interactions in psychopharmacology
    Stanley W Carson
    Department of Pharmacy, Department of Psychiatry, CB 7360, Beard Hall, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7360, USA
    Psychopharmacol Bull 36:67-81. 2002
    ..More research is needed in the field of psychopharmacology to classify central nervous system-active P-gp substrates and to characterize the utility of modulating P-gp activity at the blood-brain barrier...

Research Grants42

  1. Modulation of Opioid Effects by Garlic Supplements
    Danny Shen; Fiscal Year: 2007
    ..The results will guide further studies on the liability of adverse herb-drug interactions with garlic in chemotherapy and palliative treatment of cancer. [unreadable] [unreadable]..
  2. American Society of Pharmacognosy 47th Annual Meeting: Natural Products on Target
    John Cassady; Fiscal Year: 2007
    ..abstract_text> ..
  3. Early Identification of Adverse Reactions to Herbs
    Stephen Bent; Fiscal Year: 2007
    ..Ultimately, this research strives to identify improved methods for the early detection of adverse events, providing patients with a safer environment to achieve the potential benefits of herbal products. ..
  4. Ginkgo Biloba Extract & The Insulin Resistance Syndrome
    George Kudolo; Fiscal Year: 2004
    ..The results of this study should also provide valuable information for designing new therapeutic strategies for the treatment of diseases in the insulin resistance syndrome. ..
  5. CAM Curriculum at the University of Washington
    Ronald Schneeweiss; Fiscal Year: 2005
    ..abstract_text> ..
  6. Herb-Drug Glucuronidation Interactions
    Reginald F Frye; Fiscal Year: 2011
    ....
  7. Safety, Efficacy, and Mechanisms in American Ginseng in HIV-Related Fatigue
    Adriana S A Andrade; Fiscal Year: 2012
    ..This proposal will allow us to rigorously investigate a novel treatment for HIV- related fatigue and expand the current knowledge of herbal-ARV interactions. ..
  8. Computer-based Patient Provider Communication about CAM Use
    WILLIAM Z TAN; Fiscal Year: 2011
    ....
  9. A Data-mining Approach to CAM Medication Reconciliation
    WILLIAM Z TAN; Fiscal Year: 2012
    ....
  10. COMPOSITION, ACTIVITY AND DRUG INTERACTIONS OF ECHINACEA
    CYNTHIA WENNER; Fiscal Year: 2004
    ..By addressing these aims, Dr. Wenner will gain strong research skills in botanical medicine and the expertise necessary to significantly impact this field. ..
  11. Effects of Ginseng and Ginkgo on Drug Disposition in Man
    Aryeh Hurwitz; Fiscal Year: 2003
    ..Interactions of chronic ginseng and ginkgo with drug-metabolizing pathways and with cognitive function will thus be determined. ..
  12. AGING AND CYP-MEDIATED HERB-DRUG INTERACTIONS
    Bill Gurley; Fiscal Year: 1999
    ..John's wort modulate specific hepatic CYP activities (i.e. CYP1A2, CYP2D6, CYP2E1, and CYP3A4); and (2) whether aging potentiates the risk of CYP-mediated herb-drug interactions. ..
  13. Transcription Activation-Based Herb-Drug Interactions
    Jian Yang; Fiscal Year: 2009
    ....
  14. Herb Drug Interactions
    Gary Henderson; Fiscal Year: 2004
    ..abstract_text> ..
  15. Clinical Assessment of Herb-Drug Interactions
    Bill Gurley; Fiscal Year: 2005
    ..e. CYPIA2, CYP2D6 and CYP3A4); and (3) whether prolonged herb use can modulate P-gp-mediated drug absorption and elimination. ..
  16. International Center of TCM for Cancer
    Lorenzo Cohen; Fiscal Year: 2004
    ....
  17. Acupuncture treatment for post-thoracotomy pain syndrome
    Barrie Cassileth; Fiscal Year: 2007
    ..The research has the potential of leading to a new treatment option to improve the quality of life of cancer patients and cancer survivors. [unreadable] [unreadable] [unreadable]..
  18. THE PATHOGENESIS OF AUTOIMMUNITY IN A MURINE MODEL OF PRIMARY BILIARY CIRRHOSIS
    MERRILL E GERSHWIN; Fiscal Year: 2010
    ..abstract_text> ..
  19. Antipsychotics and Mortality in Older Patients
    HELEN KALES; Fiscal Year: 2009
    ..The results of this study will be of immediate relevance to clinicians and policymakers. ..
  20. Biobehavioral Effects of Yoga During Cancer Treatment
    Lorenzo Cohen; Fiscal Year: 2007
    ..abstract_text> ..
  21. Integrative Oncology Research Training Program at MSKCC
    Barrie Cassileth; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  22. Racial Differences in Geriatric Antidepressant Adherence
    HELEN KALES; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  23. Organic Anion Transporters 2 & 3 in Renal & Toxicity
    DOUGLAS SWEET; Fiscal Year: 2008
    ..abstract_text> ..
  24. Functional Impact of PENS for 65+ Chronic Low Back Pain
    Debra Weiner; Fiscal Year: 2006
    ....
  25. Screening Herbs for Drug Interactions
    JOHN MARKOWITZ; Fiscal Year: 2002
    ..Further, the proposed studies will complement existing and future NCCAM studies of agents such as St. John's wort and Gingko biloba. ..
  26. PRESURGICAL STRESS REDUCTION MENTAL HEALTH AND CANCER
    Lorenzo Cohen; Fiscal Year: 2002
    ..We hypothesize that pre-surgical stress management will reduce the negative impact of RP assessed by psychological, physiological, and quality of life measures. ..
  27. Acupuncture Treatment of Chronic Pain in Pancreatic Ca
    Barrie Cassileth; Fiscal Year: 2002
    ..Otherwise, an additional 19 patients will be accrued. A Phase III trial will be deemed warranted if there are 6 or more responses in total; this is consistent with a 30 percent response rate. ..
  28. Methodology of Phase I and II trials of anticancer CAM
    Andrew Vickers; Fiscal Year: 2004
    ....
  29. Acupuncture for hot flashes in cancer pts: pilot for RCT
    Barrie Cassileth; Fiscal Year: 2004
    ....
  30. Pharmacotherapy for Minor Depression
    Robert Howland; Fiscal Year: 2004
    ..The results of this study will have profound public health implications by improving our understanding of the efficacy of SJW and standard antidepressants for the treatment of MinorD. ..
  31. Society for Integrative Oncology
    Barrie Cassileth; Fiscal Year: 2004
    ..This application requests support from NIH to cover costs that remain after anticipated organizational/donor support and registration fees are taken into account. ..
  32. Massage for Treatment of Pain Advanced Cancer
    Barrie Cassileth; Fiscal Year: 2002
    ..trial could be completed in less than two years, and if the 95 percent confidence interval for the difference between group means includes at least a 20 percent lower mean post-treatment pain score on massage than sham treatment ..
  33. Osteopuncture for OA-Associated Knee Pain & Disability
    Debra Weiner; Fiscal Year: 2005
    ..In addition, mechanisms of action will be explored, and the impact of osteopuncture on health care costs determined. ..
  34. Biobehavioral Effects of Emotional Expression in Cancer
    Lorenzo Cohen; Fiscal Year: 2006
    ..The effects of the intervention should be evident throughout recovery and across indices of quality of life, mental health, subjective symptoms of stress, and immune function. ..
  35. Effects of Hypericum Perforatum on Oral Contraceptives
    Patricia Murphy; Fiscal Year: 2002
    ..A concurrent aim is the development and refinement of a methodology for evaluating the risk of ovulation and unintended pregnancy from use of other herbs or medications during oral contraceptive use. ..
  36. COMPUTER AIDED STRESS REDUCTION, MENTAL HEALTH & CANCER
    Lorenzo Cohen; Fiscal Year: 2002
    ....
  37. St. John's Wort Effects on Levonorgestrel
    Patricia Murphy; Fiscal Year: 2006
    ..The study protocol will be refined for use in future studies of levonorgestrel and other emergency contraceptive regimens. ..
  38. Ginkgo biloba for ECT-induced Memory Deficits
    JOHN MARKOWITZ; Fiscal Year: 2003
    ..will utilize larger groups and additional cognitive tests will be incorporated to provide more definitive conclusions regarding efficacy, optimal dose and duration, persistence of effects, and safety and tolerability ..
  39. Scientific Advances in CAM by Allied Health and Nursing
    Riva Touger Decker; Fiscal Year: 2003
    ..Intended outcomes of the annual conferences include electronically published proceedings, new and collaborative research and CAM research agendas and priorities for allied health and nursing that can be shared with the key associations. ..
  40. P-Glycoprotein and Disposition of Psychostimulants
    JOHN MARKOWITZ; Fiscal Year: 2005
    ....
  41. BORAGE OIL AND GINKGO BILOBA (EGb 761) IN ASTHMA
    MERRILL GERSHWIN; Fiscal Year: 2004
    ..It is hoped that findings from these studies will evolve relatively non-toxic therapeutic alternatives for attenuating bronchial hyperresponsiveness and inflammation in patients with asthma. ..