somatosensory evoked potentials

Summary

Summary: The electric response evoked in the cerebral cortex by stimulation of afferent pathways from peripheral nerves to cerebrum.

Top Publications

  1. ncbi Somatosensory evoked potentials as a marker of disease burden in type 3 Gaucher disease
    M A Garvey
    Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
    Neurology 56:391-4. 2001
  2. pmc Bilateral somatosensory evoked potentials following intermittent theta-burst repetitive transcranial magnetic stimulation
    Azra Premji
    Department of Kinesiology, University of Waterloo, Waterloo, Canada
    BMC Neurosci 11:91. 2010
  3. ncbi Objective examination for two-point stimulation using a somatosensory oddball paradigm: an MEG study
    Kosuke Akatsuka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Clin Neurophysiol 118:403-11. 2007
  4. ncbi The somatotopic organization of cytoarchitectonic areas on the human parietal operculum
    Simon B Eickhoff
    Institut fur Medizin, Forschungszentrum Julich, Julich, Germany
    Cereb Cortex 17:1800-11. 2007
  5. ncbi Predictability of the target stimulus for sensory-guided movement modulates early somatosensory cortical potentials
    Wynn Legon
    Department of Kinesiology and Health Science, York University, Toronto, Ont, Canada
    Clin Neurophysiol 117:1345-53. 2006
  6. ncbi Accuracy of cerebral monitoring in detecting cerebral ischemia during carotid endarterectomy: a comparison of transcranial Doppler sonography, near-infrared spectroscopy, stump pressure, and somatosensory evoked potentials
    Stefan Moritz
    Department of Anesthesiology, University of Regensburg, Regensburg, Germany
    Anesthesiology 107:563-9. 2007
  7. ncbi Abnormalities of cortical excitability and cortical inhibition in cervical dystonia Evidence from somatosensory evoked potentials and paired transcranial magnetic stimulation recordings
    Petr Kanovsky
    1st Department of Neurology, Masaryk University, St Anne Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    J Neurol 250:42-50. 2003
  8. ncbi Cortical neurophysiology of anticipatory anxiety: an investigation utilizing steady state probe topography (SSPT)
    M Gray
    Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, 400 Burwood Road Hawthorn 3122, Victoria, Australia
    Neuroimage 20:975-86. 2003
  9. ncbi Early neural correlates of conscious somatosensory perception
    Satu Palva
    BioMag Laboratory, Engineering Centre, Helsinki University Central Hospital, FIN 00029 Helsinki, Finland
    J Neurosci 25:5248-58. 2005
  10. ncbi Somatosensory evoked potentials during a rubber-hand illusion in schizophrenia
    Avi Peled
    Institute for Psychiatric Studies, Sha ar Menashe Mental Health Center, Mobile Post Hefer 38814, Hadera, Israel
    Schizophr Res 64:157-63. 2003

Research Grants

Detail Information

Publications249 found, 100 shown here

  1. ncbi Somatosensory evoked potentials as a marker of disease burden in type 3 Gaucher disease
    M A Garvey
    Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
    Neurology 56:391-4. 2001
    The authors compared stretch-evoked somatosensory evoked potentials (SEP) of 18 type 3 Gaucher disease (GD3) patients (two with progressive myoclonus epilepsy [PME]) with 22 age-matched normal controls and six patients with type 1 (..
  2. pmc Bilateral somatosensory evoked potentials following intermittent theta-burst repetitive transcranial magnetic stimulation
    Azra Premji
    Department of Kinesiology, University of Waterloo, Waterloo, Canada
    BMC Neurosci 11:91. 2010
    ..The present study investigated the effects of iTBS on subcortical and early cortical somatosensory evoked potentials (SEPs) recorded over left, iTBS stimulated SI and the right-hemisphere non-stimulated SI...
  3. ncbi Objective examination for two-point stimulation using a somatosensory oddball paradigm: an MEG study
    Kosuke Akatsuka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Clin Neurophysiol 118:403-11. 2007
    ..To establish an objective two-point discrimination test using magnetoencephalography (MEG)...
  4. ncbi The somatotopic organization of cytoarchitectonic areas on the human parietal operculum
    Simon B Eickhoff
    Institut fur Medizin, Forschungszentrum Julich, Julich, Germany
    Cereb Cortex 17:1800-11. 2007
    ....
  5. ncbi Predictability of the target stimulus for sensory-guided movement modulates early somatosensory cortical potentials
    Wynn Legon
    Department of Kinesiology and Health Science, York University, Toronto, Ont, Canada
    Clin Neurophysiol 117:1345-53. 2006
    ..Specifically, we hypothesized that early somatosensory evoked potentials (SEPs) would be facilitated during performance of continuous sensory-guided movement requiring ..
  6. ncbi Accuracy of cerebral monitoring in detecting cerebral ischemia during carotid endarterectomy: a comparison of transcranial Doppler sonography, near-infrared spectroscopy, stump pressure, and somatosensory evoked potentials
    Stefan Moritz
    Department of Anesthesiology, University of Regensburg, Regensburg, Germany
    Anesthesiology 107:563-9. 2007
    ..This study compares the accuracy of cerebral monitoring systems in detecting cerebral ischemia during carotid endarterectomy...
  7. ncbi Abnormalities of cortical excitability and cortical inhibition in cervical dystonia Evidence from somatosensory evoked potentials and paired transcranial magnetic stimulation recordings
    Petr Kanovsky
    1st Department of Neurology, Masaryk University, St Anne Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    J Neurol 250:42-50. 2003
    ..e. it is located within the hemisphere contralateral to the direction of head deviation...
  8. ncbi Cortical neurophysiology of anticipatory anxiety: an investigation utilizing steady state probe topography (SSPT)
    M Gray
    Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, 400 Burwood Road Hawthorn 3122, Victoria, Australia
    Neuroimage 20:975-86. 2003
    ....
  9. ncbi Early neural correlates of conscious somatosensory perception
    Satu Palva
    BioMag Laboratory, Engineering Centre, Helsinki University Central Hospital, FIN 00029 Helsinki, Finland
    J Neurosci 25:5248-58. 2005
    ....
  10. ncbi Somatosensory evoked potentials during a rubber-hand illusion in schizophrenia
    Avi Peled
    Institute for Psychiatric Studies, Sha ar Menashe Mental Health Center, Mobile Post Hefer 38814, Hadera, Israel
    Schizophr Res 64:157-63. 2003
    ..These findings support the hypothesis of alterations in associative higher-level neuronal activity in schizophrenia. The findings support previous results pointing to alterations in associative brain regions in schizophrenia...
  11. ncbi Task-relevant modulation of contralateral and ipsilateral primary somatosensory cortex and the role of a prefrontal-cortical sensory gating system
    W Richard Staines
    Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario M4N 3M5, Canada
    Neuroimage 15:190-9. 2002
    ..We conclude that SI modulation is dependent on task relevancy and that this modulation may be regulated, at least in part, by the prefrontal cortex...
  12. ncbi Functional relevance of cross-modal plasticity in blind humans
    L G Cohen
    Human Cortical Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1428, USA
    Nature 389:180-3. 1997
    ..We propose that this cross-modal plasticity may account in part for the superior tactile perceptual abilities of blind subjects...
  13. ncbi Impaired tactile acuity in old age is accompanied by enlarged hand representations in somatosensory cortex
    Tobias Kalisch
    Department of Theoretical Biology, Institute for Neuroinformatics, Ruhr University Bochum, Bochum, Germany
    Cereb Cortex 19:1530-8. 2009
    ..Whereas learning-related map changes are assumed to result from specific strengthening of synaptic connections, we suggest that the age-related map changes are related to the reduction of intracortical inhibition developing with age...
  14. ncbi Serial processing in the human somatosensory system
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Cereb Cortex 14:851-7. 2004
    ..5, 18.0, 22.4 and 21.7 ms, respectively. The differences of onset latencies among these activations indicated the serial mode of processing both through the postcentral gyrus and through the primary and secondary somatosensory cortices...
  15. ncbi Somatosensory evoked potentials and high frequency oscillations are differently modulated by theta burst stimulation over primary somatosensory cortex in humans
    Takayuki Katayama
    Sobell Department of Motor Neuroscience and Movement Disorders, University College London, London WC1N 3BG, UK
    Clin Neurophysiol 121:2097-103. 2010
    ..This study aimed to extend these observations to sensory cortex...
  16. ncbi Temporal analysis of cortical mechanisms for pain relief by tactile stimuli in humans
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Cereb Cortex 16:355-65. 2006
    ....
  17. ncbi Somatosensory processing during movement observation in humans
    S Rossi
    Dipartimento di Neuroscienze, Sezione Neurologia, UO Neurofisiopatologia, Universita di Siena, Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy
    Clin Neurophysiol 113:16-24. 2002
    ..A neural system matching action observation and execution seems to operate in the human brain, but its possible role in processing sensory inputs reaching the cortex during movement observation is unknown...
  18. ncbi Pain-Related somatosensory evoked potentials
    R Kakigi
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    J Clin Neurophysiol 17:295-308. 2000
    The authors reviewed basic and clinical reports of pain-related somatosensory evoked potentials (SSEP) after high-intensity electrical stimulation [pain SSEP(E)] and painful laser stimulation [pain SSEP(L)]...
  19. ncbi Anticipatory electroencephalography alpha rhythm predicts subjective perception of pain intensity
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Universita La Sapienza, Rome, Italy
    J Pain 7:709-17. 2006
    ....
  20. ncbi Distinct effects of attention and affect on pain perception and somatosensory evoked potentials
    Ramona Kenntner-Mabiala
    Department of Psychology Biological Psychology, Clinical Psychology, and Psychotherapy, University of Wurzburg, Marcusstrasse 9 11, D 97070 Wurzburg, Germany
    Biol Psychol 78:114-22. 2008
    The influence of affect and attention on sensory and affective pain as well as on somatosensory evoked potentials in response to painful and nonpainful electrical stimuli was investigated in a single experimental design...
  21. ncbi Monitoring of motor evoked potentials compared with somatosensory evoked potentials and microvascular Doppler ultrasonography in cerebral aneurysm surgery
    Georg Neuloh
    Klinik und Poliklinik fur Neurochirurgie, Rheinische Friedrich Wilhelms Universitat, Bonn, Germany
    J Neurosurg 100:389-99. 2004
    The aims of this study were to compare the efficiency of motor evoked potentials (MEPs), somatosensory evoked potentials (SSEPs), and microvascular Doppler ultrasonography (MDU) in the detection of impending motor impairment from ..
  22. ncbi Laminar and columnar organization of ascending excitatory projections to layer 2/3 pyramidal neurons in rat barrel cortex
    Gordon M G Shepherd
    Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA
    J Neurosci 25:5670-9. 2005
    ....
  23. ncbi Effect of transcranial DC sensorimotor cortex stimulation on somatosensory evoked potentials in humans
    Kaoru Matsunaga
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, 8 11 Queen Square, London WC1N 3BG, UK
    Clin Neurophysiol 115:456-60. 2004
    To study the after-effect of transcranial direct current stimulation (tDCS) over the sensorimotor cortex on the size of somatosensory evoked potentials (SEPs) in humans.
  24. pmc Sustained increase of somatosensory cortex excitability by tactile coactivation studied by paired median nerve stimulation in humans correlates with perceptual gain
    Oliver Höffken
    Department of Neurology, BG Kliniken Bergmannsheil, Buerkle de la Camp Platz 1, 44789 Bochum, Germany
    J Physiol 584:463-71. 2007
    ..Conceivably, changes of cortical excitability seem to constitute an additional important marker and mechanism underlying plastic reorganization...
  25. ncbi Differential modulation of the short- and long-latency somatosensory evoked potentials in a forewarned reaction time task
    Tetsuo Kida
    Doctoral Program in Health and Sports Sciences, University of Tsukuba, Tsukuba, Japan
    Clin Neurophysiol 115:2223-30. 2004
    We investigated modulation of the short- and long-latency somatosensory evoked potentials (SEPs) in a forewarned reaction time task.
  26. ncbi Load- and cadence-dependent modulation of somatosensory evoked potentials and Soleus H-reflexes during active leg pedaling in humans
    Masanori Sakamoto
    Division of Health and Sport Education, United Graduate School of Education, Tokyo Gakugei University, 1 33 Yayoi cho, Inage Ku, Chiba City 263 8522, Japan
    Brain Res 1029:272-85. 2004
    ..Cerebral somatosensory evoked potentials (SEPs) and Soleus (Sol) H-reflexes following posterior tibial nerve stimulation were recorded at four ..
  27. ncbi Somatosensory evoked potentials and EEG findings in siblings of juvenile myoclonic epilepsy patients
    D Atakli
    Bakirköy State Hospital for Neurologic and Psychiatric Diseases, Istanbul, Turkey
    Epileptic Disord 1:173-7. 1999
    ....
  28. ncbi Different neuronal contribution to N20 somatosensory evoked potential and to CO2 laser evoked potentials: an intracerebral recording study
    Massimiliano Valeriani
    Department of Neurology, Universita Cattolica del Sacro Cuore, L go A Gemelli 8, 00168 Rome, Italy
    Clin Neurophysiol 115:211-6. 2004
    ..To investigate the possible contribution of the primary somatosensory area (SI) to pain sensation...
  29. ncbi Upper limb H reflexes and somatosensory evoked potentials modulated by movement
    J D Brooke
    Human Neurophysiology Laboratory, Department of Human Biology and Nutritional Sciences, University of Guelph, Ontario, Guelph, Canada
    J Electromyogr Kinesiol 10:211-5. 2000
    In the human lower limb, the magnitudes of both Hoffmann (H) reflexes and primary somatosensory evoked potentials (SEPs) from scalp electrodes, are reduced by active and/or passive movement...
  30. ncbi Somatosensory evoked potentials in severe traumatic brain injury: a blinded study
    J W Sleigh
    Department of Intensive Care, Waikato Hospital, Hamilton, New Zealand
    J Neurosurg 91:577-80. 1999
    ..The aims of this study were to correlate the results of SSEP recordings with the outcome in a prospectively blinded manner and to assess whether monitoring of SSEPs was a useful adjunct to clinical judgment in the prediction of outcome...
  31. ncbi Somatosensory evoked potentials in the telencephalon of Atlantic salmon (Salmo salar) following galvanic stimulation of the tail
    Janicke Nordgreen
    Department of Pharmacology and Toxicology, Norwegian School of Veterinary Science, Oslo, Norway
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 193:1235-42. 2007
    ..The results added to the body of literature indicates that the exteroceptive senses are represented by processing within the telencephalon of the fish...
  32. ncbi fMRI reflects functional connectivity of human somatosensory cortex
    Maria Blatow
    Division of Neuroradiology, Department of Neurology, University of Heidelberg Medical School, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Neuroimage 37:927-36. 2007
    ..Thus, the assessment of human somatosensory function with fMRI may permit in the future investigations of pathological conditions...
  33. ncbi Tibial nerve somatosensory evoked potentials in dogs with degenerative lumbosacral stenosis
    Björn P Meij
    Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Vet Surg 35:168-75. 2006
    To determine somatosensory evoked potentials (SEPs) in dogs with degenerative lumbosacral stenosis (DLS) and in healthy dogs.
  34. ncbi Motor and somatosensory evoked potentials in Autosomal Dominant Hereditary Spastic Paraparesis (ADHSP) linked to chromosome 2p, SPG4
    F Sartucci
    Department of Neurosciences, Clinical Neurology, Pisa University Medical School, Pisa, Italy
    Brain Res Bull 74:243-9. 2007
    ..and cortical excitability, using Transcranial Magnetic Stimulation (TMS) as well as short latency Somatosensory Evoked Potentials (SEPs) in Autosomal Dominant Hereditary Spastic Paraparesis (ADHSP) patients...
  35. ncbi Premovement gating of somatosensory evoked potentials after tibial nerve stimulation
    Kotaro Asanuma
    Department of Neurology, Graduate School of Medicine, Kyoto University, Syogoin Sakyo Ku, Kyoto 606 8503, Japan
    Neuroreport 14:375-9. 2003
    b>Somatosensory evoked potentials (SEPs) are attenuated or gated during movement. The mechanism for this includes both centrifugal gating of afferent input and competition with other afferents caused by the movement (peripheral gating)...
  36. ncbi Contrasting behavior of beta event-related synchronization and somatosensory evoked potential after median nerve stimulation during finger manipulation in man
    G Pfurtscheller
    Department of Medical Informatics, Institute of Biomedical Engineering, University of Technology Graz, Inffeldgasse 16a, A 8010 Graz, Austria
    Neurosci Lett 323:113-6. 2002
    ..The results suggest that both phenomena can be interpreted as responses of different neuronal structures in sensorimotor areas...
  37. ncbi Median nerve somatosensory evoked potentials and upper limb motor function in hemiparesis
    B K Park
    Department of Physical Medicine and Rehabilitation, Case Western Reserve University, Cleveland, OH, USA
    Electromyogr Clin Neurophysiol 43:169-79. 2003
    ..Contrary to prior reports, median nerve SEP appears to have a weak correlational relationship with clinical measures of upper limb function in hemiparesis...
  38. ncbi Two psychophysical channels of whisker deflection in rats align with two neuronal classes of primary afferents
    Maik C Stüttgen
    Abteilung für Kognitive Neurologie, Hertie Institut für Klinische Hirnforschung, Universitat Tubingen, 72076 Tubingen, Germany
    J Neurosci 26:7933-41. 2006
    ..This suggests that detection performance in both channels is based on the assessment of very few spikes in their corresponding groups of primary afferents...
  39. ncbi Parametric modeling of somatosensory evoked potentials using discrete cosine transform
    O Bai
    Department of Advanced Systems Control Engineering, Graduate School of Science and Engineering, Saga University, Honjomachi, Japan
    IEEE Trans Biomed Eng 48:1347-51. 2001
    This paper introduces a parametric method for identifying the somatosensory evoked potentials (SEPs). The identification was carried out by using pole-zero modeling of the SEPs in the discrete cosine transform (DCT) domain...
  40. ncbi A comparative magnetoencephalographic study of cortical activations evoked by noxious and innocuous somatosensory stimulations
    K Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroscience 120:235-48. 2003
    ..Our data also implied that activities in the amygdala/hippocampal formation represented common effects of noxious and tactile stimulations...
  41. ncbi Activation of a distributed somatosensory cortical network in the human brain. A dipole modelling study of magnetic fields evoked by median nerve stimulation. Part I: Location and activation timing of SEF sources
    F Mauguiere
    Department of Functional Neurology and Epileptology, Hopital Neurologique, Lyon, France
    Electroencephalogr Clin Neurophysiol 104:281-9. 1997
    ..However the long-lasting activations of all sources and their overlap in time is also compatible with a top-down control mediated via backward projections...
  42. ncbi Transcranial direct current stimulation disrupts tactile perception
    Andreas Rogalewski
    Department of Neurology, University of Muenster, Albert Schweitzer Strasse 33, 48129 Muenster, Germany
    Eur J Neurosci 20:313-6. 2004
    ..This finding offers a new perspective for the treatment of conditions characterized by alterations of cortical excitability...
  43. ncbi Excitability of the Adelta nociceptive pathways as assessed by the recovery cycle of laser evoked potentials in humans
    A Truini
    Department of Neurological Sciences, University La Sapienza, Viale Università 30, 00185, Rome, Italy
    Exp Brain Res 155:120-3. 2004
    ....
  44. ncbi Effect of spinal transcutaneous direct current stimulation on somatosensory evoked potentials in humans
    Filippo Cogiamanian
    Dipartimento di Scienze Neurologiche, Universita di Milano, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Padiglione Ponti, Via F Sforza 35, Milano 20122, Italy
    Clin Neurophysiol 119:2636-40. 2008
    ..Aiming to modulate human spinal cord function non-invasively, we evaluated whether transcutaneous direct current (DC) stimulation induces long-lasting changes in conduction along the sensory spinal pathways...
  45. ncbi Somatosensory evoked potentials associated with thermal activation of type II Adelta mechanoheat nociceptive afferents
    S W Harkins
    Department of Gerontology, Phychiatry and Biomedical Engineering, Virginia Commonnealth University, Richmond 23298 0266, USA
    Int J Neurosci 104:93-111. 2000
    ..EPs to painful contact thermal stimuli may be of value in the evaluation of small fiber peripheral neuropathies and assessment of altered pain states...
  46. ncbi Sensory and motor interfering influences on somatosensory evoked potentials
    G Cheron
    Laboratory of Physiology, ISEPK, Free University of Brussels, Belgium
    J Clin Neurophysiol 17:280-94. 2000
    The interfering influences by which the different components of the early somatosensory evoked potentials are modified are reviewed from both neurophysiologic and clinical perspectives...
  47. ncbi Plasticity and stability of somatosensory maps in thalamus and cortex
    K Fox
    Cardiff School of Biosciences, Cardiff University, Wales, UK
    Curr Opin Neurobiol 10:494-7. 2000
    ....
  48. ncbi Percutaneous tibial nerve stimulation produces effects on brain activity: study on the modifications of the long latency somatosensory evoked potentials
    Enrico Finazzi-Agrò
    Department of Surgery, Chair of Urology, Tor Vergata University, Tor Vergata University Hospital, Rome, Italy
    Neurourol Urodyn 28:320-4. 2009
    Long-latency somatosensory evoked potentials (LL-SEP) provide information on the function of somatosensory cortical structures. Percutaneous tibial nerve stimulation (PTNS) is indicated in the treatment of lower urinary tract dysfunction...
  49. ncbi Somatosensory evoked potentials reflect the upper limb motor performance in multiple sclerosis
    Viviana Nociti
    Institute of Neurology, Catholic University, Roma, Italy
    J Neurol Sci 273:99-102. 2008
    The aim of this multicentric study was to multidimensionally evaluate the relationship among somatosensory evoked potentials (SEPs) parameters, patient's perspective and clinical measures of the upper limb impairment in patients with ..
  50. pmc Time-frequency component analysis of somatosensory evoked potentials in rats
    Zhi Guo Zhang
    Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong, PR China
    Biomed Eng Online 8:4. 2009
    ..The purpose of this study is to measure and identify detailed time-frequency components in normal SEP using time-frequency analysis (TFA) methods and to obtain their distribution pattern in the time-frequency domain...
  51. ncbi Contact heat evoked potentials to painful and non-painful stimuli: effect of attention towards stimulus properties
    Domenica Le Pera
    Laboratory for Experimental Pain Research, Center for Sensory Motor Interaction, Aalborg University, Aalborg, Denmark
    Brain Topogr 15:115-23. 2002
    ..The high activation level of each of these area or their spatial neighbouring might explain the strong similarity of CHEP components recorded during different attentional manipulations...
  52. ncbi Passive enhancement of the somatosensory P100 and N140 in an active attention task using deviant alone condition
    Tetsuo Kida
    Doctoral Program in Health and Sports Sciences, University of Tsukuba, Tennoudai 1 1 1, Tsukuba City, Japan
    Clin Neurophysiol 115:871-9. 2004
    ..We investigated the changes in the somatosensory P100 and N140 during passive (reading) versus active tasks (counting, button pressing) and oddball (target=20%, standard=80%) versus deviant alone conditions (standards were omitted)...
  53. ncbi Somatosensory evoked potentials during mild hypothermia after cardiopulmonary resuscitation
    A Bouwes
    Department of Intensive Care, C3 423, Academic Medical Center, P O Box 22660, 1100 DD, Amsterdam, The Netherlands
    Neurology 73:1457-61. 2009
    ..cardiopulmonary resuscitation (CPR), the bilateral absence of cortical N20 responses of median nerve somatosensory evoked potentials (SSEP) 24 hours after admission invariably correlates with a poor neurologic outcome...
  54. ncbi Intraoperative monitoring using somatosensory evoked potentials. A position statement by the American Society of Neurophysiological Monitoring
    J Richard Toleikis
    IONM, Department of Anesthesiology, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    J Clin Monit Comput 19:241-58. 2005
    ..American Society of Neurophysiological Monitoring on the recommended appropriate and correct use of somatosensory evoked potentials as an intraoperative neurophysiological monitoring tool to protect patient well-being during surgery...
  55. ncbi Predictive value of somatosensory evoked potentials for long-lasting pain relief after spinal cord stimulation: practical use for patient selection
    Marc P Sindou
    Department of Neurosurgery and UPRES EA 1880, University of Lyon, Hôpital Neurologique P Wertheimer, 59 Boulevard Pinel, F 69003 Lyon, France
    Neurosurgery 52:1374-83; discussion 1383-4. 2003
    ..electrodes-specifically, assessment of neural conduction in the dorsal columns with the use of somatosensory evoked potentials (SSEPs)...
  56. ncbi Value of dermatomal somatosensory evoked potentials in detecting acute nerve root injury: an experimental study with special emphasis on stimulus intensity
    Tse Min Tsai
    Department of Orthopedics, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Spine (Phila Pa 1976) 30:E540-6. 2005
    ..Pre- and post-transection patterns and rates of change of corresponding nerve roots were compared to determine accuracy...
  57. ncbi The diagnostic value of dermatomal somatosensory evoked potentials in lumbosacral disc herniations: a critical approach
    K Yazicioglu
    Gulhane Military Medical Academy, Ankara, Turkey
    Electromyogr Clin Neurophysiol 39:175-81. 1999
    In this study, we examined scalp recorded dermatomal somatosensory evoked potentials (DSEPs) to electrical stimulation of L4, L5 and S1 dermatomes in 55 patients with proven lumbosacral radiculopathy and in 22 healthy subjects...
  58. ncbi The effect of sleep deprivation on median nerve somatosensory evoked potentials
    Daniella Terney
    Clinical Neurophysiology Laboratory, Department of Neurology, Albert Szent Gyorgyi Medical and Pharmaceutical Center, University of Szeged, Hungary
    Neurosci Lett 383:82-6. 2005
    ..the effect of one night's sleep deprivation on the early and middle-latency median nerve (MN) somatosensory evoked potentials (SEPs)...
  59. pmc BOLD fMRI and somatosensory evoked potentials are well correlated over a broad range of frequency content of somatosensory stimulation of the rat forepaw
    Artem G Goloshevsky
    Laboratory of Functional and Molecular Imaging, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Brain Res 1195:67-76. 2008
    ..have reported good correlation between the blood oxygenation level-dependent (BOLD) fMRI signal and somatosensory evoked potentials (SEPs) using short, typically 300 micros, square stimulation pulses...
  60. ncbi Spatial coincidence modulates interaction between visual and somatosensory evoked potentials
    Martin Schürmann
    Institute of Physiology, Medical University Lubeck, 23538 Lubeck, Germany
    Neuroreport 13:779-83. 2002
    ..These interaction effects hint at a temporo-spatial pattern of multiple brain areas participating in the process of multimodal integration...
  61. ncbi Multilevel somatosensory evoked potentials and cerebrospinal proteins: indicators of spinal cord injury in thoracoabdominal aortic aneurysm surgery
    Anders Winnerkvist
    Department of Cardiothoracic Surgery and Anaesthesiology, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
    Eur J Cardiothorac Surg 31:637-42. 2007
    Multilevel somatosensory evoked potentials (SSEP) and the release of biochemical markers in cerebrospinal fluid (CSF) were investigated to identify patients with spinal cord ischemia during thoracoabdominal aortic repair and/or a ..
  62. ncbi Median nerve somatosensory evoked potentials and their high-frequency oscillations in amyotrophic lateral sclerosis
    Masashi Hamada
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 118:877-86. 2007
    To investigate sensory cortical changes in amyotrophic lateral sclerosis (ALS), we studied somatosensory evoked potentials (SEPs) and their high-frequency oscillation potentials.
  63. ncbi Comparative source localization of electrically and pressure-stimulated multichannel somatosensory evoked potentials
    Wolfram Kawohl
    Psychiatric University Hospital, Zurich, Switzerland
    J Clin Neurophysiol 24:257-62. 2007
    ..The somatosensory evoked potentials after electrical stimulation showed sharper peaks and higher amplitudes than the pressure stimulated ..
  64. ncbi Hypohydration and muscular fatigue of the thumb alter median nerve somatosensory evoked potentials
    Scott J Montain
    Military Nutrition Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Appl Physiol Nutr Metab 35:456-63. 2010
    ..The purpose of this study was to determine the effect of hypohydration on somatosensory evoked potentials (SEPs) at rest and during recovery from fatiguing exercise...
  65. ncbi Motor and somatosensory evoked potentials are well maintained in patients given dexmedetomidine during spine surgery
    Endrit Bala
    Department of Outcomes Research, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio 44195, USA
    Anesthesiology 109:417-25. 2008
    ..Therefore, the authors tested the hypothesis that dexmedetomidine does not have a clinically important effect on somatosensory and transcranial motor evoked responses...
  66. ncbi Short and middle-latency Median Nerve (MN) SEPs recorded by depth electrodes in human pre-SMA and SMA-proper
    C Barba
    Fondazione Santa Lucia, IRCCS, Rome, Italy
    Clin Neurophysiol 116:2664-74. 2005
    ....
  67. ncbi Itching-related somatosensory evoked potentials
    Hideki Mochizuki
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Pain 138:598-603. 2008
    ..When the right wrist was stimulated, the reaction time (RT) and latency of the positive component of somatosensory evoked potentials (P1) were 1215 ms and 963 ms, respectively...
  68. ncbi Sustained attention modulates the immediate effect of de-afferentation on the cortical representation of the digits: source localization of somatosensory evoked potentials in humans
    H Buchner
    Department of Neurology, University Clinic, Aachen, Germany
    Neurosci Lett 260:57-60. 1999
    ..We present a source localization study using somatosensory evoked potentials (SEP) following electric stimulation of digits one and five before and during anaesthesia of digits ..
  69. ncbi Immediate cortical reorganization after local anesthetic block of the thumb: source localization of somatosensory evoked potentials in human subjects
    T D Waberski
    Department of Neurology, University Hospital Aachen, Pauwelsstrasse 30, D 52057, Aachen, Germany
    Neurosci Lett 347:151-4. 2003
    ..We present a source localization study using equivalent current dipole modeling of somatosensory evoked potentials (SEPs) following mechanical air-puff stimulation of the first, second and third digits before and ..
  70. ncbi Heterotopic ischemic pain attenuates somatosensory evoked potentials induced by electrical tooth stimulation: diffuse noxious inhibitory controls in the trigeminal nerve territory
    Keiko Fujii
    Anesthesiology and Clinical Physiology, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Yushima, Bunkyo ku, Japan
    Eur J Pain 10:495-504. 2006
    The purpose of this study was to determine whether the late component of somatosensory evoked potentials (SEP) induced by electrical tooth stimulation and pain intensity are inhibited by heterotopic ischemic stimulation...
  71. ncbi Abnormal somatosensory evoked potentials indicate compressive cervical myelopathy in mucopolysaccharidoses
    R Boor
    University Children s Hospital, Johannes Gutenberg University, Mainz, Germany
    Neuropediatrics 31:122-7. 2000
    ..However, we feel that the SEP analysis is useful to detect functional impairment of the cervical cord in patients with MPS...
  72. ncbi Human brain oscillatory activity phase-locked to painful electrical stimulations: a multi-channel EEG study
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Universita di Roma La Sapienza, Rome, Italy
    Hum Brain Mapp 15:112-23. 2002
    ..This enriches the actual debate on the mapping of event-related oscillatory activity of human brain...
  73. ncbi Somatosensory evoked potentials by median nerve stimulation in children during thiopental/sevoflurane anesthesia and the additive effects of ketoprofen and fentanyl
    Susanna Westerén-Punnonen
    Department of Clinical Neurophysiology, Kuopio University Hospital, P O Box 1777, FI 70211 Kuopio, Finland
    Anesth Analg 107:799-805. 2008
    b>Somatosensory evoked potentials (SEPs) are used to determine the spinal cord and brain function during surgical procedures...
  74. ncbi Effects of spinal cord stimulation on the cortical somatosensory evoked potentials in failed back surgery syndrome patients
    Hubert Polacek
    Charles University Prague, Department of Normal, Pathological and Clinical Physiology, Third Faculty of Medicine, Ke Karlovu 4, Prague 2, Czech Republic
    Clin Neurophysiol 118:1291-302. 2007
    ..To evaluate the functional activation of the somatosensory cortical regions in neuropathic pain patients during therapeutic spinal cord stimulation (SCS)...
  75. ncbi Cerebral oximetry does not correlate with electroencephalography and somatosensory evoked potentials in determining the need for shunting during carotid endarterectomy
    Mark L Friedell
    Department of Surgical Education, Orlando Regional Healthcare, Orlando, Florida, USA
    J Vasc Surg 48:601-6. 2008
    ..This study was performed to compare the efficacy of rSO(2) with electroencephalography (EEG) and median nerve somatosensory evoked potentials (SSEP) in determining when to place a shunt during CEA.
  76. ncbi Comparative study between gadobenate dimeglumine and gadobutrol in rats with brain ischemia: evaluation of somatosensory evoked potentials
    V Frigeni
    Milano Research Centre, Bracco Imaging SpA, Milan, Italy
    Invest Radiol 36:561-72. 2001
    The present study had two main objectives: to validate a rat model of brain ischemia in terms of somatosensory evoked potentials (SEPs) and to compare, using the validated model, the potential activity on the somatosensory function of ..
  77. ncbi Utility of somatosensory evoked potentials in chronic acquired demyelinating neuropathy
    Con Yiannikas
    Department of Neurology, Concord Hospital, Hospital Road, Concord, 2139 Sydney, Australia
    Muscle Nerve 38:1447-54. 2008
    ..b>Somatosensory evoked potentials (SSEPs) assess proximal segments of sensory nerves, inadequately assessed by routine nerve conduction ..
  78. ncbi Brain volume analyses and somatosensory evoked potentials in multiple system atrophy
    Satoko Miyatake
    Department of Neurology, Higashi Saitama National Hospital, Hasuda, Saitama, Japan
    J Neurol 257:419-25. 2010
    ..The median nerve somatosensory evoked potentials (SEPs) were recorded, and the latencies and amplitudes of N9, N11, P13/14, N20 and P25 components ..
  79. ncbi Electrophysiologic intraoperative monitoring for spine procedures
    Jefferson C Slimp
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Box 356490, Seattle, WA 98195, USA
    Phys Med Rehabil Clin N Am 15:85-105. 2004
    ..MEPs and reflex monitoring, which address the descending pathways and the interneuronal connections, is efficacious in detecting abnormalities that may be missed by SEPs...
  80. ncbi Quantifying interhemispheric symmetry of somatosensory evoked potentials with the intraclass correlation coefficient
    Wilma J G van de Wassenberg
    Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Clin Neurophysiol 25:139-46. 2008
    Although large intersubject variability is reported for cortical somatosensory evoked potentials (SEPs), variability between hemispheres within one subject is thought to be small...
  81. ncbi Effects of temporary clips on somatosensory evoked potentials in aneurysm surgery
    Uta Schick
    Clinic of Neurological Surgery, University of Leipzig, Germany
    Neurocrit Care 2:141-9. 2005
    Changes in somatosensory evoked potentials (SEPs) were used to identify cerebral ischemia and to predict neurological outcome during the application of temporary clips in aneurysm surgery.
  82. ncbi Combined motor and somatosensory evoked potentials for intraoperative monitoring: intra- and postoperative data in a series of 69 operations
    M R Weinzierl
    Department of Neurosurgery, University of Aachen, Aachen, Germany
    Neurosurg Rev 30:109-16; discussion 116. 2007
    ..Stable SSEP/MEP recordings reassure the surgeon that motor function is still intact and surgery can be continued safely. The combined SSEP/ MEP monitoring becomes advantageous, if one modality is not recordable...
  83. pmc A clinical and EEG scoring system that predicts early cortical response (N20) to somatosensory evoked potentials and outcome after cardiac arrest
    Cedric Daubin
    Department of Medical Intensive Care, Caen University Hospital, Caen, France
    BMC Cardiovasc Disord 8:35. 2008
    ..The aim of the current research was to construct a clinical and EEG scoring system that predicts early cortical response (N20) to somatosensory evoked potentials and 6-months outcome in comatose patients after cardiac arrest.
  84. ncbi Analysis of motor and somatosensory evoked potentials during thoracic and thoracoabdominal aortic aneurysm repair
    Kourosh Keyhani
    Cardiothoracic and Vascular Surgery, University of Texas Medical School Houston, Houston, Texas, USA
    J Vasc Surg 49:36-41. 2009
    Use of motor evoked potentials (MEP) and somatosensory evoked potentials (SSEP) monitoring during thoracic and thoracoabdominal aortic surgery is controversial...
  85. ncbi Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions
    Carl C H Petersen
    Department of Cell Physiology, Max Planck Institute for Medical Research, Heidelberg D 69120, Germany
    J Neurosci 23:1298-309. 2003
    ....
  86. pmc Layer- and cell-type-specific suprathreshold stimulus representation in rat primary somatosensory cortex
    C P J de Kock
    Department of Cell Physiology, Max Planck Institute for Medical Research, Jahnstrasse 29, D 69120 Heidelberg, Germany
    J Physiol 581:139-54. 2007
    ..Finally, L5 thick-tufted cells dominated the cortical AP output following sensory stimulation, suggesting that these cells could direct sensory guided behaviours...
  87. pmc Improvement of tactile discrimination performance and enlargement of cortical somatosensory maps after 5 Hz rTMS
    Martin Tegenthoff
    Department of Neurology, Ruhr University Bochum, BG Kliniken Bergmannsheil, Bochum, Germany
    PLoS Biol 3:e362. 2005
    ..The underlying properties and processes that allow cortical networks, after being modified through TMS pulses, to reach new organized stable states that mediate better performance remain to be clarified...
  88. ncbi Effect of theta burst stimulation over the human sensorimotor cortex on motor and somatosensory evoked potentials
    Seiko Ishikawa
    Department of Rehabilitation and Physical Medicine, Kagoshima University, Kagoshima, Japan
    Clin Neurophysiol 118:1033-43. 2007
    ..To study the after-effect of theta burst stimulation (TBS) over the left sensorimotor cortex on the size of somatosensory as well as motor evoked potentials evoked from both hemispheres in healthy human subjects...
  89. ncbi Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex
    Dori Derdikman
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Neurosci 23:3100-5. 2003
    ..By using new, improved VSD, the present findings shed new light on the spatial parameters of the intricate spatiotemporal cortical interplay of inhibition and excitation...
  90. ncbi Deciphering the spike train of a sensory neuron: counts and temporal patterns in the rat whisker pathway
    Ehsan Arabzadeh
    Cognitive Neuroscience Sector, International School for Advanced Studies, 34014 Trieste, Italy
    J Neurosci 26:9216-26. 2006
    ..In some cases, patterns permitted discriminations not supported by spike counts alone...
  91. ncbi Clinical usefulness of laser-evoked potentials
    Rolf Detlef Treede
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Saarstr 21, 55099 Mainz, Germany
    Neurophysiol Clin 33:303-14. 2003
    ..evoked potentials, the somatosensory pathway cannot be investigated as a whole by conventional somatosensory evoked potentials (SEP), because these only reflect function of large fibers, dorsal columns, medial lemniscus and ..
  92. pmc Attenuation of N2 amplitude of laser-evoked potentials by theta burst stimulation of primary somatosensory cortex
    Csaba Poreisz
    Department of Clinical Neurophysiology, Georg August University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Exp Brain Res 185:611-21. 2008
    ..Furthermore, imTBS produced responses similar to those observed by other forms of TBS induced excitability changes in the SI...
  93. pmc Shifts in cortical representations predict human discrimination improvement
    B Pleger
    Department of Neurology, Ruhr-University Bochum, BG-Kliniken Bergmannsheil, Buerkle-de-la-Camp-Platz 1, D-44789 Bochum, Germany
    Proc Natl Acad Sci U S A 98:12255-60. 2001
    ..Plastic processes related to the improvement were localized in primary somatosensory cortex and were scaled with the degree of the individual perceptual improvement...
  94. ncbi Prediction of poor outcome within the first 3 days of postanoxic coma
    E G J Zandbergen
    Department of Neurology and Clinical Neurophysiology, Academic Medical Centre, University of Amsterdam, Nijmegen, The Netherlands
    Neurology 66:62-8. 2006
    ....
  95. ncbi EFNS guidelines on neuropathic pain assessment
    G Cruccu
    EFNS Panel on Neuropathic Pain Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Eur J Neurol 11:153-62. 2004
    ..A laboratory measure of pain that by-passes the subjective report, and thus cognitive influences, is a hopeful aim for the future...
  96. ncbi Modulated activation of the human SI and SII cortices during observation of hand actions
    Sari Avikainen
    Brain Research Unit, Low Temoerature Laboratory, Helsinki University of Technology, Otakaari 3A, FIN 02015 HUT, Espoo, Finland
    Neuroimage 15:640-6. 2002
    ..Our results suggest that the SI and SII cortices contribute to the human mirror-neuron system, possibly providing information necessary for preserving the sense of self during action observation...
  97. ncbi Use of intraoperative monitoring of somatosensory evoked potentials to prevent ischaemic stroke after surgical exclusion of middle cerebral artery aneurysms
    G Penchet
    Service de Neurochirurgie, Centre Hospitalier Pellegrin, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Acta Neurochir (Wien) 149:357-64. 2007
    The aim of this study was to assess the value of monitoring somatosensory evoked potentials (SEP) in the prevention of ischaemic stroke occurring during surgical exclusion of middle cerebral artery aneurysms.
  98. pmc Coupling between somatosensory evoked potentials and hemodynamic response in the rat
    Maria Angela Franceschini
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 13th Street Bldg 149 room 2301, Charlestown, MA 02129, USA
    Neuroimage 41:189-203. 2008
    We studied the relationship between somatosensory evoked potentials (SEP) recorded with scalp electroencephalography (EEG) and hemoglobin responses recorded non-invasively with diffuse optical imaging (DOI) during parametrically varied ..
  99. ncbi Characteristics of mid- to long-latency spinal somatosensory evoked potentials following spinal trauma in the rat
    Benjamin M Ellingson
    Department of Biomedical Engineering, Marquette University, Milwaukee, Wisconsin 53201 1881, USA
    J Neurotrauma 25:1323-34. 2008
    ..was to develop and implement a new technique for repeated monitoring of spinal mid- to long-latency somatosensory evoked potentials (SpSEPs) during sciatic nerve stimulation following recovery from spinal cord injury (SCI) in rats...
  100. ncbi Impaired dynamic balance control in adolescents with idiopathic scoliosis and abnormal somatosensory evoked potentials
    Miko L M Lao
    Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong, China
    J Pediatr Orthop 28:846-9. 2008
    ..An intergroup comparative study was conducted to investigate the effect of abnormal somatosensory function on the dynamic balance parameters of girls with AIS...
  101. ncbi Steady-state somatosensory evoked potentials: suitable brain signals for brain-computer interfaces?
    Gernot R Müller-Putz
    Laboratory of Brain Computer Interfaces, Institute for Computer Graphics and Vision, Graz University of Technology, 8010 Graz, Austria
    IEEE Trans Neural Syst Rehabil Eng 14:30-7. 2006
    ..In this work, a BCI system is introduced based on steady-state somatosensory evoked potentials (SSSEPs)...

Research Grants62

  1. ESPRIT Evoked Potential Monitoring of Acute Intracranial Mass Lesions
    David Sherman; Fiscal Year: 2006
    ..by developing technology for real-time objective assessment of brain function at the bedside, using somatosensory evoked potentials (SEP)...
  2. Consequences of Cardiac Arrest: Brain Injury
    NITISH VYOMESH THAKOR; Fiscal Year: 2013
    ..marked by abnormal coupling of thalamic and cortical potentials, b) quantitative analysis of cortical somatosensory evoked potentials (SSEP) will track recovery of normal thalamocortical coupling, and c) entropy-based quantitative EEG (..
  3. Diffusion tensor imaging of the injured spinal cord
    Shekar N Kurpad; Fiscal Year: 2013
    ..are related to functional connectivity of the spinal cord, evidenced by correlations with spinal somatosensory evoked potentials (SSEPs)...
  4. Training-Induced Plasticity in Human Motor and Sensory Systems
    David J Ostry; Fiscal Year: 2013
    ..Imaging the sensory and motor networks of the brain that are associated with both somatosensory and motor learning may also lead to better diagnoses and tracking of brain neuroplasticity during therapy. ..
  5. CONTROLLED STUDY OF INFANT HIV ENCEPHALOPATHY
    David Coulter; Fiscal Year: 1992
    ..Electrodiagnostic testing (EEG and visual, auditory and somatosensory evoked potentials) and psychological testing (Bayley, Farran, Stein) will be obtained at 6, 12 and 24 months...
  6. POTENTIATION OF OPIATE ANALGESIA BY ELECTROSTIMULATION
    MALCOLM SKOLNICK; Fiscal Year: 1992
    ..proposal requests support for measurement of the effect of analgesic agents, TE and/or morphine on somatosensory evoked potentials (SEP's) transduced from single recording electrodes in nociceptively responsive nuclei...
  7. EVOKED POTENTIALS IN CONGENITAL HIV INFECTION
    RON EMERSON; Fiscal Year: 1991
    The overall goal if this study is to evaluate median nerve somatosensory evoked potentials as an objective measure of HIV encephalopathy in children...
  8. BIOBEHAVIORAL CORRELATES OF ADDED LOADS IN LUNG DISEASE
    Andrew Harver; Fiscal Year: 1991
    ..Both exogenous (i.e., short-latency, somatosensory evoked potentials) and endogenous potentials (i.e...
  9. COMMUNICATION DISORDERS IN CHILDREN
    Walt Jesteadt; Fiscal Year: 1991
    ..fine force control and evoked perioral muscle response, perioral mechano-sensitivity, and trigeminal somatosensory evoked potentials. Project V deals with the genetics of sensorineural hearing loss, applying recombinant DNA marker ..
  10. TREATMENT OUTCOMES IN MODERATELY LEAD TOXIC CHILDREN
    John Rosen; Fiscal Year: 1993
    ..osteocalcin concentrations in serum; 2) central nervous system dysfunction as indexed by auditory and somatosensory evoked potentials; and 3) behavioral deficits as reflected by global measures of intelligence in addition to specific ..
  11. SENSORY AND MOTOR PROCESSING
    Colum MacKinnon; Fiscal Year: 2000
    ..Transcortical feedback loop times will be further examined by recording somatosensory evoked potentials to median nerve stimulation, and muscle contractions evoked by transcranial magnetic stimulation over ..
  12. INTRAOPARATIVE NEUROLOGICAL MONITOR (INM)
    ANANTH NATARAJAN; Fiscal Year: 2001
    ..We strongly agree with this sentiment. Our collaborative group has been studying somatosensory evoked potentials (SEPs) from a basic science viewpoint for the past decade...
  13. PROPOSAL FOR AN AIDS DEMENTIA CENTER
    Colin Hall; Fiscal Year: 1992
    ..two cohorts, to include: routine and quantitative EEG; visual, brainstem auditory, P3 cognitive and somatosensory evoked potentials; in the adults, nerve conduction and fiber density studies...
  14. NON-INVASIVE OPTICAL IMAGING OF THE HUMAN BRAIN
    MARIA FRANCESCHINI; Fiscal Year: 2002
    ..abstract_text> ..
  15. A NEW PEDIATRIC MODEL OF ISCHEMIC STROKE IN PIGLETS
    John Kuluz; Fiscal Year: 2005
    ....
  16. Corticospinal development after cortical inactivation
    KATHLEEN FRIEL; Fiscal Year: 2005
    ....
  17. Depression and Altered Pain Perception
    LAURA SYMONDS; Fiscal Year: 2004
    ..The methods to be used are psychological mood scales, delivery of phasic electric shock and tonic cold pressor pain, and functional magnetic resonance imaging during delivery of pain stimuli in different mood states. ..
  18. Dendritic Processing in the Olfactory Bulb
    Jason Christie; Fiscal Year: 2003
    ..The specific aims are: (1) to determine the function of autoexcitation in mitral cell processing and (2) to determine how dendritic compartmentalization effects mitral cell processing. ..
  19. Ischemic Spasticity: Modulation by GAD65 Gene Delivery
    Martin Marsala; Fiscal Year: 2010
    ....
  20. Epidermal Innervation as an Outcome Measure
    David Herrmann; Fiscal Year: 2006
    ..Dr. Herrmann will also examine a method to simplify the analysis of skin biopsy specimens, for easier application in large clinical trials. ..
  21. Deep Brain Stimulation Using Microactuated Microprobes
    Jit Muthuswamy; Fiscal Year: 2006
    ..Future developments of this technology could lead to an efficient delivery vehicle for drug or gene therapy. ..
  22. Restoring Conduction in Chronically Injured Spinal Cord
    Daniel Smith; Fiscal Year: 2006
    ..The results generated by the proposed study will serve as the foundation for additional pre-clinical development that will advance novel treatments of chronic SCI toward the human clinic. [unreadable] [unreadable]..
  23. Spatial aspects of coding in piriform cortex
    KURT ILLIG; Fiscal Year: 2007
    ..abstract_text> ..
  24. Non-viral controllable gene delivery for neuroprotection
    JAMES HECKER; Fiscal Year: 2007
    ..Neuroprotection strategies designed for pre-operative use will also have significant application for attenuation of secondary injury following stroke, brain or spinal cord trauma, or neurodegenerative diseases. ..
  25. Neurophysiology of Multisensory Integration
    John Foxe; Fiscal Year: 2007
    ..Through these studies, we will begin to explore the neural mechanisms underlying the process of "binding," related inputs across the separate sensory modalities. ..
  26. STIMULUS-SPECIFIC SI CORTICOCORTICAL INTERACTIONS
    Barry Whitsel; Fiscal Year: 2007
    ..abstract_text> ..
  27. Trauma to Immature Brain: Response Repair & Treatment
    Ann Christine Duhaime; Fiscal Year: 2008
    ..recovery of the piglet somatosensory cortex using serial functional magnetic resonance imaging and somatosensory evoked potentials. The overall goal of this research is to use these data to develop a stratified treatment trial ..
  28. PHYSIOLOGICAL BASES OF MAGNETOENCEPHALOGRAPHY
    Yoshio Okada; Fiscal Year: 2008
    ..The role of calcium-mediated current in evoked response will be determined by a combination of optical measurements of intracellular calcium concentration, intra- and extracellular potentials. ..
  29. Cortical current imaging in human infants with babySQUID
    Yoshio Okada; Fiscal Year: 2008
    ..We believe that this project, if successful, will open new windows into brain development in healthy infants as well as infants with various neurological disorders. [unreadable] [unreadable] [unreadable]..
  30. Genetics of Familial Episodic Ataxia
    Joanna C Jen; Fiscal Year: 2010
    ..Insights gained from the study will lead to improved diagnosis and treatment of familial episodic ataxia and the more common episodic vertigo syndromes. ..
  31. Pathobiology of Retinal Vasculopathy with Cerebal Leukodystrophy (RVCL)
    Joanna C Jen; Fiscal Year: 2010
    ..abstract_text> ..
  32. Single neuronal recordings using movable mircrophobes
    JITENDRAN MUTHUSWAMY; Fiscal Year: 2010
    ....
  33. Control of Repetitive Movement in Parkinson's Disease
    Colum MacKinnon; Fiscal Year: 2009
    ..This project is relevant to public health because the findings will provide a better understanding of the human basal ganglia and its role in the production of disordered movement and help to develop improved treatments. ..
  34. SPINAL MOTOR CONDUCTION AND RECOVERY AFTER HUMAN SCI
    Blair Calancie; Fiscal Year: 2009
    ..A slow-release formulation the K-channel blocker 4-aminopyridine will be tested for its effects on conduction in some cases. ..
  35. Development of semicircular canal prostheses for studies of vestibular plasticity
    DANIEL MERFELD; Fiscal Year: 2009
    ..abstract_text> ..
  36. Adolescent Neurodevelopment and Alcohol
    Robert Thoma; Fiscal Year: 2008
    ..abstract_text> ..
  37. Dynamic Magnetic Resonance Inverse Imaging of the Human Brain
    Fa Hsuan Lin; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  38. THE GENETIC & FUNCTIONAL ANATOMICAL BASIS OF HGPPS
    Joanna Jen; Fiscal Year: 2009
    ..Understanding the anatomical and molecular basis of HGPPS will provide insight into the genetically programmed neurodevelopment of the conjugate horizontal gaze center and other cranial nuclei in the brainstem. ..
  39. fMRI BOLD contrast relationship to cerebrovascular tone
    Todd Parrish; Fiscal Year: 2006
    ..The theme of this proposal is to investigate the impact of physiologic mechanisms (reactivity, flow, hematocrit, neuronal activity) on the generation of BOLD signal and more importantly BOLD contrast. ..
  40. REGULATION OF SEROTONERGIC NEUROTRANSMISSION
    Donald Edwards; Fiscal Year: 2004
    ..The use to which serotonin is put by the HGNs will be determined, as will the effects of serotonin uptake on other adjacent and well-studied serotonergic systems, including those that modulate posture and escape. ..
  41. Cognitive Control in Aging
    John Foxe; Fiscal Year: 2004
    ..High-density ERP recordings and topographic mapping will permit us to assess the relative contributions of frontal, parietal and earlier sensory areas to these processes. ..
  42. REPAIRING SENSORY PATHWAYS AFTER SPINAL CORD INJURY
    STEPHEN ONIFER; Fiscal Year: 2004
    ....
  43. EVALUATION OF MEG AS A CURRENT SOURCE IMAGING TECHNIQUE
    Yoshio Okada; Fiscal Year: 2004
    ..We hope to use these results as the basis for planning an infant study which will be started as soon as the babySQUID becomes available. ..
  44. BODY WEIGHT SUPPORTED AMBULATION TRAINING AFTER SCI
    Blair Calancie; Fiscal Year: 2004
    ..abstract_text> ..
  45. Neural Mechanisms of Selectively Biasing Attentional Set
    John Foxe; Fiscal Year: 2003
    ....
  46. TRAUMA TO THE DEVELOPING BRAIN--RESPONSE AND TREATMENT
    Ann Christine Duhaime; Fiscal Year: 2002
    ..This important information will be useful in the development and testing of head injury therapies appropriate for infants and children. ..
  47. ACUTE REPAIR OF SPINAL INJURY WITH FUSOGENS
    Richard Borgens; Fiscal Year: 2002
    ..An anatomical evaluation of the degree of axonal repair between control and PEG treated spinal cords using a horseradish peroxidase dye exclusion test and conventional histology. ..
  48. Whole-Head MEG System for Brain Research
    Martin Reite; Fiscal Year: 2002
    ..The instrument will be located in the Biomagnetic Imaging Lab in the Department of Psychiatry. Instrument management and scheduling will be supervised by an Advisory Committee established for this purpose. ..
  49. FUNCTIONAL MRI OF REAL AND SHAM ACUPUNCTURE
    Todd Parrish; Fiscal Year: 2002
    ....
  50. Online MRI Positioning and Real-Time Motion Correction
    Andre van der Kouwe; Fiscal Year: 2004
    ..The technology will be evaluated in a group of healthy volunteers. ..
  51. Ischemic Paraplegia: Modulation by Stem Cell Implant
    Martin Marsala; Fiscal Year: 2005
    ....
  52. Neurofeedback functional MRI
    Seung Schik Yoo; Fiscal Year: 2006
    ....
  53. International Conference on Episodic Ataxia Syndromes
    Joanna Jen; Fiscal Year: 2005
    ..abstract_text> ..
  54. FAST ELECTRICAL OSCILLATIONS IN SOMATOSENSORY CORTEX
    DANIEL BARTH; Fiscal Year: 2006
    ..abstract_text> ..
  55. Adaptation to controlled vestibular stimulation
    DANIEL MERFELD; Fiscal Year: 2005
    ..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
  56. CENTRAL GUSTATORY ELECTROPHYSIOLOGY IN MICE
    Stuart McCaughey; Fiscal Year: 2005
    ..abstract_text> ..
  57. Prevention of Postraumatic Neocortical Epileptogenesis
    Kevin Graber; Fiscal Year: 2005
    ....
  58. Cognitive Function After Intracranial Aneurysm Surgery
    Satwant Samra; Fiscal Year: 2005
    ..Information gained from this investigation will be important in giving a prognosis for returning back to work as well as planning rehabilitation of patients suffering from aneurysmal SAH in future. ..
  59. SYNAPTIC INTEGRATION AND PLASTICITY IN COMMAND NEURONS
    Donald Edwards; Fiscal Year: 2005
    ..This will be studied with standard electrophyiological techniques. ..
  60. SPINAL NEURAL ACTIVITY--ROLE IN POST ISCHEMIC INJURY
    Martin Marsala; Fiscal Year: 2001
    ..The role of HSP72 expression in protection will be tested by examining the effects of antisense pretreatment on HSP72 expression and the same three measures of ischemic damage. ..
  61. In-Vivo Confocal Imaging of Meissner's Corpuscles as a Measure of HIV Neuropathy
    David Herrmann; Fiscal Year: 2008
    ..In-vivo RCM of MCs may prove to have wide application for early identification of sensory peripheral neuropathies, and to assess effectiveness of therapy. [unreadable] [unreadable] [unreadable]..
  62. Calculating Dynamic CMRO2 Changes Using CBF & BOLD fMRI
    Alberto Vazquez; Fiscal Year: 2008
    ..These methods can be used in the clinical setting to assess tissue viability and function in the brain as well as other organs. [unreadable] [unreadable] [unreadable]..