contingent negative variation

Summary

Summary: An increasing negative shift of the cortical electrical potentials associated with an anticipated response to an expected stimulus. It is an electrical event indicative of a state of readiness or expectancy.

Top Publications

  1. ncbi Mismatch negativity in schizophrenia: a meta-analysis
    Daniel Umbricht
    University of Zurich, Department of Psychiatric Research, Psychiatric University Hospital Zurich, Switzerland
    Schizophr Res 76:1-23. 2005
  2. ncbi Wait and see
    C H Brunia
    Department of Psychonomics, Tilburg University, 5000 LE Tilburg, The Netherlands
    Int J Psychophysiol 43:59-75. 2001
  3. ncbi Deviant matters: duration, frequency, and intensity deviants reveal different patterns of mismatch negativity reduction in early and late schizophrenia
    Juanita Todd
    School of Psychology, University of Newcastle, Callaghan, Australia
    Biol Psychiatry 63:58-64. 2008
  4. ncbi Cortical plasticity induced by short-term unimodal and multimodal musical training
    Claudia Lappe
    Institute for Biomagnetism and Biosignalanalysis, University of Munster, 48149 Munster, Germany
    J Neurosci 28:9632-9. 2008
  5. ncbi Mismatch negativity: different water in the same river
    T W Picton
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Canada
    Audiol Neurootol 5:111-39. 2000
  6. pmc Are auditory-evoked frequency and duration mismatch negativity deficits endophenotypic for schizophrenia? High-density electrical mapping in clinically unaffected first-degree relatives and first-episode and chronic schizophrenia
    Elena Magno
    The Cognitive Neurophysiology Laboratory, St Vincent s Hospital, Dublin, Ireland
    Biol Psychiatry 64:385-91. 2008
  7. ncbi Acute dopamine D(1) and D(2) receptor stimulation does not modulate mismatch negativity (MMN) in healthy human subjects
    Sumie Leung
    Biological Psychiatry Research Unit, Brain Sciences Institute, Faculty of Life and Social Sciences, Swinburne University of Technology, Melbourne, Australia
    Psychopharmacology (Berl) 194:443-51. 2007
  8. ncbi Planning of visually guided reach-to-grasp movements: inference from reaction time and contingent negative variation (CNV)
    Manuel Zaepffel
    Institut de Neurosciences Cognitives de la Mediterranee, UMR 6193, CNRS, Universite de la Mediterranee, Marseille, France
    Psychophysiology 49:17-30. 2012
  9. ncbi The CNV peak: an index of decision making and temporal memory
    Francoise Macar
    Laboratoire de Neurobiologie de la Cognition, Centre National de la Recherche Scientifique, Marseille, France
    Psychophysiology 40:950-4. 2003
  10. ncbi Electrophysiological indices of automatic and controlled auditory information processing in first-episode, recent-onset and chronic schizophrenia
    Daniel S G Umbricht
    Exploratory Clinical Development, Translational Medicine, Novartis Pharma AG, Basel, Switzerland
    Biol Psychiatry 59:762-72. 2006

Detail Information

Publications232 found, 100 shown here

  1. ncbi Mismatch negativity in schizophrenia: a meta-analysis
    Daniel Umbricht
    University of Zurich, Department of Psychiatric Research, Psychiatric University Hospital Zurich, Switzerland
    Schizophr Res 76:1-23. 2005
    ..Many studies have reported abnormalities in the generation of MMN in schizophrenia. The objective of this study was to assess the magnitude of this deficit and associated factors...
  2. ncbi Wait and see
    C H Brunia
    Department of Psychonomics, Tilburg University, 5000 LE Tilburg, The Netherlands
    Int J Psychophysiol 43:59-75. 2001
    ..They are known as the readiness potential (RP), the contingent negative variation (CNV) and the stimulus preceding negativity (SPN)...
  3. ncbi Deviant matters: duration, frequency, and intensity deviants reveal different patterns of mismatch negativity reduction in early and late schizophrenia
    Juanita Todd
    School of Psychology, University of Newcastle, Callaghan, Australia
    Biol Psychiatry 63:58-64. 2008
    ....
  4. ncbi Cortical plasticity induced by short-term unimodal and multimodal musical training
    Claudia Lappe
    Institute for Biomagnetism and Biosignalanalysis, University of Munster, 48149 Munster, Germany
    J Neurosci 28:9632-9. 2008
    ....
  5. ncbi Mismatch negativity: different water in the same river
    T W Picton
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Canada
    Audiol Neurootol 5:111-39. 2000
    ..Improvements in the techniques for measuring the MMN and in the paradigms for eliciting it will be needed before the MMN can become clinically useful as an objective measurement of such disorders in individual patients...
  6. pmc Are auditory-evoked frequency and duration mismatch negativity deficits endophenotypic for schizophrenia? High-density electrical mapping in clinically unaffected first-degree relatives and first-episode and chronic schizophrenia
    Elena Magno
    The Cognitive Neurophysiology Laboratory, St Vincent s Hospital, Dublin, Ireland
    Biol Psychiatry 64:385-91. 2008
    ..The aim of this study was to investigate the extent to which dysfunction in MMN generation might represent an endophenotypic marker for schizophrenia...
  7. ncbi Acute dopamine D(1) and D(2) receptor stimulation does not modulate mismatch negativity (MMN) in healthy human subjects
    Sumie Leung
    Biological Psychiatry Research Unit, Brain Sciences Institute, Faculty of Life and Social Sciences, Swinburne University of Technology, Melbourne, Australia
    Psychopharmacology (Berl) 194:443-51. 2007
    ....
  8. ncbi Planning of visually guided reach-to-grasp movements: inference from reaction time and contingent negative variation (CNV)
    Manuel Zaepffel
    Institut de Neurosciences Cognitives de la Mediterranee, UMR 6193, CNRS, Universite de la Mediterranee, Marseille, France
    Psychophysiology 49:17-30. 2012
    ..show that reach-to-grasp movements generate differences in the topographic distribution of the late Contingent Negative Variation (ICNV) amplitude between the 4 precuing conditions...
  9. ncbi The CNV peak: an index of decision making and temporal memory
    Francoise Macar
    Laboratoire de Neurobiologie de la Cognition, Centre National de la Recherche Scientifique, Marseille, France
    Psychophysiology 40:950-4. 2003
    A slow brain potential change, the contingent negative variation (CNV), was recorded in a temporal generalization schedule. The task was to judge the duration of a signal (1.250 to 3...
  10. ncbi Electrophysiological indices of automatic and controlled auditory information processing in first-episode, recent-onset and chronic schizophrenia
    Daniel S G Umbricht
    Exploratory Clinical Development, Translational Medicine, Novartis Pharma AG, Basel, Switzerland
    Biol Psychiatry 59:762-72. 2006
    ....
  11. ncbi Error and feedback processing in children with ADHD and children with Autistic Spectrum Disorder: an EEG event-related potential study
    Yvonne Groen
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, P O Box 660, 9700 AR Groningen, The Netherlands
    Clin Neurophysiol 119:2476-93. 2008
    ....
  12. pmc Looking for a pattern: an MEG study on the abstract mismatch negativity in musicians and nonmusicians
    Sibylle C Herholz
    Institute for Biomagnetism and Biosignalanalysis, University of Munster, Malmedyweg 15, D 48149 Munster, Germany
    BMC Neurosci 10:42. 2009
    ....
  13. ncbi How do children prepare to react? Imaging maturation of motor preparation and stimulus anticipation by late contingent negative variation
    Stephan Bender
    Department for Child and Adolescent Psychiatry, University of Heidelberg, Blumenstrasse 8, 69115 Heidelberg, Germany
    Neuroimage 27:737-52. 2005
    ..healthy right-handed children aged 6 to 18 years and analyzed the topography of the late component of contingent negative variation (lCNV) in a 64-electrode high density sensor array...
  14. pmc Changes in the activity of the cerebral cortex relate to postural response modification when warned of a perturbation
    Jesse V Jacobs
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, OR, USA
    Clin Neurophysiol 119:1431-42. 2008
    ..To determine whether the cerebral cortex contributes to modifying upcoming postural responses to external perturbations when provided with prior warning of the perturbation...
  15. ncbi Fronto-parietal networks activation during the contingent negative variation period
    Carlos M Gomez
    Dept de Psicologia Experimental, Universidad de Sevilla, Facultad de Psicologia, C Camilo José Cela S N, Sevilla 41018, Spain
    Brain Res Bull 73:40-7. 2007
    ....
  16. ncbi Effects of neck flexion on contingent negative variation and anticipatory postural control during arm movement while standing
    Katsuo Fujiwara
    Department of Human Movement and Health, Graduate School of Medical Science, Kanazawa University, 13 1 Takara machi, Kanazawa 920 8640, Japan
    J Electromyogr Kinesiol 19:113-21. 2009
    We investigated the effects of neck flexion on contingent negative variation (CNV) and anticipatory postural control using an arm flexion task in standing...
  17. pmc Developmental changes of the contingent negative variation in migraine and healthy children
    Michael Siniatchkin
    Department of Child Neurology, Christian Albrechts University of Kiel, Schwanenweg 20, Kiel, Germany
    J Headache Pain 11:105-13. 2010
    ..We performed a longitudinal study and recorded contingent negative variation (CNV), an event-related slow cortical potential, in migraine children (n = 27) and age-matched healthy ..
  18. ncbi Behavioural treatment programme contributes to normalization of contingent negative variation in children with migraine
    Michael Siniatchkin
    Neuropaediatric Department, Paediatric Hospital, Christian Albrechts University, Schwanenweg 20, Kiel, Germany
    Cephalalgia 31:562-72. 2011
    ..In this pilot study, special behavioural training of habituation to aversive stimuli (MIPAS-Family = Migraine Patient Seminar for Families) was developed and proven effective in children suffering from migraine without aura...
  19. ncbi Contingent negative variation to emotional in- and out-group stimuli differentiates high- and low-prejudiced individuals
    Pearl Chiu
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    J Cogn Neurosci 16:1830-9. 2004
    ..The contingent negative variation (CNV ) component of the event-related potential in response to the pending presentation of in- and out-..
  20. ncbi Sensory memory during physiological aging indexed by mismatch negativity (MMN)
    Manuela Ruzzoli
    Cognitive Neuroscience Section, IRCCS San Giovanni di Dio Fatebenefratelli, Brescia, Italy
    Neurobiol Aging 33:625.e21-30. 2012
    ..Considering the advantage offered by the MMN paradigm used here, these data might be a useful reference point for the assessment of auditory sensory memory in pathological aging (e.g., in neurodegenerative diseases)...
  21. ncbi Making decisions about time: event-related potentials and judgements about the equality of durations
    Isabelle Paul
    Faculte des Sciences, Laboratoire de Psychologie et Neurosciences de la Cognition et de l Affectivité EA 4306, Universite de Rouen, 76 821 Mont Saint Aignan Rouen Cedex, France
    Biol Psychol 88:94-103. 2011
    ..Component of Timing) measured after the stimulus presentations and by a change in the P1, the CNV (Contingent Negative Variation), and its positive counterpart during the presentation of the stimulus, which were larger when the ..
  22. ncbi Differential contribution of frontal and temporal cortices to auditory change detection: fMRI and ERP results
    Bertram Opitz
    Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany
    Neuroimage 15:167-74. 2002
    ..These results suggest that the right fronto-opercular cortex is part of the neural network generating the MMN. Three alternative explanations of these findings are discussed...
  23. ncbi Mismatch negativity potentials and cognitive impairment in schizophrenia
    Torsten Baldeweg
    Institute of Child Health and Great Ormond Street Hospital, Wolfson Centre, Mecklenburgh Square, London WC1N 2AP, UK
    Schizophr Res 69:203-17. 2004
    ..This suggests that ERP measures of auditory system adaptability more appropriately characterise the pathophysiological processes underlying cognitive impairment in schizophrenia than static measures of ERP magnitude...
  24. ncbi Is there pre-attentive memory-based comparison of pitch?
    T Jacobsen
    Institut für Allgemeine Psychologie, Universitat Leipzig, Germany
    Psychophysiology 38:723-7. 2001
    ..An experimental protocol controlling for refractoriness effects was developed and a true memory-comparison-based brain response to pitch change was demonstrated...
  25. ncbi Slow cortical potentials in migraine families
    M Siniatchkin
    Institute of Medical Psychology, University of Kiel, Germany
    Cephalalgia 20:881-92. 2000
    ..influences of age, sex and familial contribution on the variance of amplitude and habituation of the contingent negative variation (CNV). Analysis of individual differences in relation to the CNV habituation was performed...
  26. ncbi Timing processes: an outline of behavioural and neural indices not systematically considered in timing models
    Francoise Macar
    Laboratoire de Neurobiologie de la Cognition, CNRS UMR 6155, Marseille, France
    Can J Exp Psychol 63:227-39. 2009
    ..of activation and attention, and on data drawn from an important electrophysiological indice, the Contingent Negative Variation (CNV)...
  27. pmc Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures
    Bruce I Turetsky
    Department of Psychiatry, 10th Floor, Gates Building, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Schizophr Bull 33:69-94. 2007
    ..We conclude with a discussion of the few studies thus far that have employed a multivariate approach with these candidates...
  28. ncbi Stereotyped topography of different elevated contingent negative variation components in children with migraine without aura points towards a subcortical dysfunction
    Stephan Bender
    Department for Child and Adolescent Psychiatry, University of Heidelberg, Blumenstrasse 8, D 69115 Heidelberg, Germany
    Pain 127:221-33. 2007
    Increased negativity during contingent negative variation (CNV) is thought to reflect abnormal neural activation in adult migraineurs' attention related processing. Findings in childhood and adolescence have yielded less clear results...
  29. ncbi The difference in Mismatch negativity between the acute and post-acute phase of schizophrenia
    Naoko Shinozaki
    Department of Neuropsychiatry, Hirosaki University School of Medicine, Zaifu cho 5, Hirosaki 036 8563, Japan
    Biol Psychol 59:105-19. 2002
    ....
  30. ncbi Adaptive control deficits in attention-deficit/hyperactivity disorder (ADHD): the role of error processing
    Catharina S Van Meel
    Department of Clinical Neuropsychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1 1081 BT Amsterdam, The Netherlands
    Psychiatry Res 151:211-20. 2007
    ..Findings are discussed in terms of anterior cingulate cortex (ACC) dysfunction, leading to a failure to predict the likelihood that an error occurs in a given context...
  31. ncbi Electroencephalographic characterization of brain dopaminergic stimulation by apomorphine in healthy volunteers
    R Luthringer
    Service du Docteur Jean Paul Macher, centre hospitalier spécialisé, FORENAP Institute for Research in Neurosciences and Psychiatry, Rouffach, France
    Neuropsychobiology 39:49-56. 1999
    ..Finally, these EEG approaches could lead to better characterization of drugs acting on dopaminergic pathways, such as antipsychotics...
  32. ncbi Current source density analysis of CNV during temporal gap paradigm
    C M Gomez
    Lab Psicobiología Dpto Psicología Experimental, Universidad de Sevilla, Spain
    Brain Topogr 13:149-59. 2001
    The present report studied the contingent negative variation during Gap and Non-Gap conditions using visual stimulation and manual responses...
  33. ncbi Processes involved in tempo perception: a CNV analysis
    Micha Pfeuty
    Neurosciences Cognitives et Imagerie Cerebrale, LENA CNRS, Hopital Salpetriere, 75651 Paris Cedex 13, France
    Psychophysiology 40:69-76. 2003
    ..b>Contingent negative variation (CNV), known to be linked to the judgment of a single interval, kept increasing in amplitude for three ..
  34. ncbi Motor programming of response force and movement direction
    R Ulrich
    University of Wuppertal, Germany
    Psychophysiology 35:721-8. 1998
    ..were assessed on the prestimulus amplitude of the lateralized readiness potential (LRP), on the contingent negative variation (CNV), and on reaction time (RT)...
  35. pmc Cluster analysis of behavioural and event-related potentials during a contingent negative variation paradigm in remitting-relapsing and benign forms of multiple sclerosis
    Javier J Gonzalez-Rosa
    Department of Experimental Psychology, University of Seville, Seville, Spain
    BMC Neurol 11:64. 2011
    ..Furthermore, we subjected our data to a cluster analysis to determine whether MS patients and healthy controls could be differentiated in terms of their psychophysiological profile...
  36. ncbi Effects of spatial separation and stimulus probability on the event-related potentials elicited by occasional changes in sound location
    Ranil R Sonnadara
    Department of Psychology, McMaster University, Hamilton, Ontario, Canada L8S 4K1
    Brain Res 1071:175-85. 2006
    ..The early latency of MMN for changes in sound location is interpreted in the context of an early-warning system to alert the organism to new sound sources in the environment...
  37. ncbi Spectral characteristics and linear-nonlinear synchronization changes of different EEG frequency bands during the CNV
    Márk Molnár
    Institute of Psychology, Hungarian Academy of Sciences, Budapest, Hungary
    Psychophysiology 45:412-9. 2008
    ....
  38. ncbi Tone duration mismatch negativity deficits predict impairment of executive function in schizophrenia
    Atsuhito Toyomaki
    Department of Psychiatry, Graduate School of Medicine, Hokkaido University N15, W7, Sapporo 060 8638, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:95-9. 2008
    ..Our finding suggests MMN deficits in schizophrenia predict deficits of executive function and might reflect ongoing functional abnormality of fronto-temporal interaction...
  39. ncbi Location of brain rhythms and their modulation by preparatory attention estimated by current density
    C M Gomez
    Psychobiology Laboratory, Department of Experimental Psychology, University of Sevilla, Spain
    Brain Res 1107:151-60. 2006
    ..find the brain areas with maximal rhythmic activity before warning and imperative stimuli in a classic contingent negative variation (CNV) paradigm, and, second, to study the modulation of the EEG rhythms of these areas during the ..
  40. ncbi Planning of rapid aiming movements and the contingent negative variation: are movement duration and extent specified independently?
    Hartmut Leuthold
    Centre for Cognitive Neuroimaging, Department of Psychology, University of Glasgow, Scotland, UK
    Psychophysiology 46:539-50. 2009
    ..Reaction time (RT) decreased and late Contingent Negative Variation (CNV) amplitude increased with the amount of advance information...
  41. ncbi Contingent negative variation elicited before jaw and tongue movements
    K Yoshida
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Sakyoku, Kyoto, Japan
    J Oral Rehabil 32:871-9. 2005
    b>Contingent negative variation (CNV) is a negative brain potential occurring between two successive stimuli when the first stimulus is a warning and the second stimulus requires a motor response...
  42. ncbi Event-related potentials accompanying motor preparation and stimulus expectancy in the young, young-old and oldest-old
    Edward J Golob
    Department of Neurology, Institute for Brain Aging and Dementia, University of California, Irvine, CA, USA
    Neurobiol Aging 26:531-42. 2005
    ..were assessed by recording brain potentials associated with motor preparation and stimulus expectancy (contingent negative variation, CNV) in young-old (60-69), oldest-old (85-98), and young (17-23) subjects...
  43. ncbi Effects of NMDA receptor antagonist memantine on mismatch negativity
    Milena Korostenskaja
    BioMag Laboratory, Helsinki University Central Hospital, Finland
    Brain Res Bull 72:275-83. 2007
    ..As memantine-induced changes in MMN were detected only in EEG, we suggest that the effect is mostly related to the frontal cortex...
  44. ncbi Effects of topiramate and levetiracetam vs placebo on habituation of contingent negative variation in migraine patients
    Marina de Tommaso
    Department of Neurological and Psychiatric Sciences, University of Bari, Italy
    Neurosci Lett 442:81-5. 2008
    ..We assessed the effects of a 2-month treatment with topiramate or levetiracetam vs placebo on contingent negative variation (CNV) habituation and amplitude in a cohort of migraine without aura (MO) patients...
  45. ncbi Effects of preparatory period on anticipatory postural control and contingent negative variation associated with rapid arm movement in standing posture
    Kaoru Maeda
    Department of Human Movement and Health, Graduate School of Medical Science, Kanazawa University, Japan
    Gait Posture 25:78-85. 2007
    ..Motor preparation state was evaluated by integrated values of the late components of the contingent negative variation (late CNV), obtained by averaging electroencephalograms during the last 100ms of the preparatory ..
  46. ncbi Lie detection with contingent negative variation
    Fang Fang
    National Laboratory on Machine Perception, Department of Psychology, Peking University, Beijing 100871, PR China
    Int J Psychophysiol 50:247-55. 2003
    topographies of contingent negative variation (CNV) were recorded in a paradigm of delayed response with feedback for three kinds of faces: familiar, strange and target...
  47. ncbi Contingent negative variation and activation of postural preparation before postural perturbation by backward floor translation at different initial standing positions
    Katsuo Fujiwara
    Department of Human Movement and Health, Graduate School of Medical Science, Kanazawa University, 13 1 Takara machi, Kanazawa 920 8640, Japan
    Neurosci Lett 490:135-9. 2011
    We investigated the effects of balance difficulty on contingent negative variation (CNV) and postural preparation against perturbation...
  48. ncbi Influence of MTHFR genotype on contingent negative variation and MRI abnormalities in migraine
    Marina de Tommaso
    Neurologic and Psychiatric Sciences, Neurological Clinical Section, University of Bari, Italy
    Headache 47:253-65. 2007
    ..The hyper-homocysteinemia may favor the vascular and neuronal mechanism underlying migraine, and the risk of stroke...
  49. ncbi Contingent negative variation before and after hemodialysis among patients with end-stage renal disease
    Jong Seok Bae
    Department of Neurology, Inje University, College of Medicine, 633 165 Gaegeum dong, Busanjin Gu, Busan 614 735, South Korea
    J Neurol Sci 267:70-5. 2008
    To investigate changes in contingent negative variation (CNV) induced by uremia and to study the effects of hemodialysis.
  50. ncbi Event-related potentials in patients with total locked-in state due to fulminant Guillain-Barré syndrome
    A Ragazzoni
    Neurology Unit, Ospedale S Maria Nuova, Florence, Italy
    Int J Psychophysiol 37:99-109. 2000
    ..ERPs allow monitoring the level of alertness and attention and appear more specific than EEG in identifying a state of awareness in patients in which communication is severely impaired as a consequence of neurological disorders...
  51. ncbi The effects on auditory neurocognitive evoked responses and contingent negative variation activity of frontal cortex lesions or ablations in man: three new case studies
    R Zappoli
    Department of Neurological and Psychiatric Sciences, University of Florence, Viale Morgagni 85, 50134, Florence, Italy
    Int J Psychophysiol 38:109-44. 2000
    ..74-1.28 ms, mean approximately 1 cm/1.02 ms ( approximately 9.8 ms)...
  52. pmc Differential effects of age and executive functions on the resolution of the contingent negative variation: a reexamination of the frontal aging theory
    Georg Dirnberger
    Department of Neurology, Medical University of Vienna, Vienna, Austria
    Age (Dordr) 32:323-35. 2010
    ..The contingent negative variation resolution (CNV-R) is an electroencephalographic potential elicited after the second (informative) ..
  53. pmc Differential Go/NoGo activity in both contingent negative variation and spectral power
    Ingrid Funderud
    Department of Neuropsychiatry and Psychosomatic Medicine, Division of Surgery and Clinical Neuroscience, Oslo University Hospital Rikshospitalet, Norway
    PLoS ONE 7:e48504. 2012
    We investigated whether both the contingent negative variation (CNV), an event-related potential index of preparatory brain activity, and event-related oscillatory EEG activity differentiated Go and NoGo trials in a delayed response task...
  54. ncbi Contingent negative variation in children with anorexia nervosa
    K Torigoe
    Department of Pediatrics, Nagaoka Red Cross Hospital, Niigata, Japan
    Pediatr Int 41:285-91. 1999
    ..The purpose of this study is to distinguish the characteristics of contingent negative variation (CNV) and postimperative negative variation (PINV), which may reflect the level of catecholamine in ..
  55. ncbi Contingent negative variation (CNV) and determinants of the post-imperative negative variation (PINV) in schizophrenic patients and healthy controls
    C Klein
    Department of Psychology, University of Konstanz, Germany
    Schizophr Res 21:97-110. 1996
    ..This result is compatible with the hypothesis of prefrontal cortical dysfunctions in schizophrenia...
  56. ncbi Topographic differences in CNV amplitude reflect different preparatory processes
    P A Leynes
    Department of Psychology, College of New Jersey, Ewing 08628 0718, USA
    Int J Psychophysiol 31:33-44. 1998
    Topographic differences in Contingent Negative Variation (CNV) were recorded while people were preparing for cognitive versus motor tasks in an S1-S2 paradigm...
  57. ncbi Anticipated action consequences as a nexus between action and perception: evidence from event-related potentials
    Andrey R Nikolaev
    Laboratory for Perceptual Dynamics, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    Biol Psychol 78:53-65. 2008
    ..These results show that anticipating action consequences involves brain systems ranging from perceptual to executive; anticipated action effects constitute a link between perception and action...
  58. ncbi ERPs and PET analysis of time perception: spatial and temporal brain mapping during visual discrimination tasks
    V Pouthas
    Unité de Neurosciences Cognitives et Imagerie Cérébrale, UPR 640 CNRS, LENA, Hopital de la Salpetriere, Paris, France
    Hum Brain Mapp 10:49-60. 2000
    ..We assume that the right frontal area plays a specific role in the formation of temporal judgments...
  59. ncbi CNV and temporal uncertainty with 'ageing' and 'non-ageing' S1-S2 intervals
    P Trillenberg
    Department of Neurology, Medical University of Lubeck, Lubeck, Germany
    Clin Neurophysiol 111:1216-26. 2000
    ..We studied how the amplitude of the contingent negative variation (CNV) is affected by temporal variation of S2 presentation...
  60. ncbi Mismatch negativity in aging and in Alzheimer's and Parkinson's diseases
    E Pekkonen
    Department of Neurology, Helsinki University Central Hospital, Finland
    Audiol Neurootol 5:216-24. 2000
    ..The MMN appears to offer an objective tool for studying auditory processing and memory trace decay in different neurological disorders...
  61. ncbi Neurophysiological reactivity before a migraine attack
    Michael Siniatchkin
    Pediatric Neurology, University of Kiel, Schwanenweg 20, 24105 Kiel, Germany
    Neurosci Lett 400:121-4. 2006
    Migraine patients are characterized by increased amplitudes and reduced habituation of the contingent negative variation (CNV) response, especially before a migraine attack...
  62. ncbi Slow EEG potentials (contingent negative variation and post-imperative negative variation) in schizophrenia: their association to the present state and to Parkinsonian medication effects
    R Verleger
    Department of Neurology, Medical University of Lubeck, Germany
    Clin Neurophysiol 110:1175-92. 1999
    Between warning signal (S1) and imperative signal (S2), the EEG shifts negatively (contingent negative variation, CNV) reflecting preparation and expectancy...
  63. ncbi Are the periodic changes of neurophysiological parameters during the pain-free interval in migraine related to abnormal orienting activity?
    M Siniatchkin
    I M Sechenov Moscow Medical Academy, Russian Autonomic Pathology Center, Russian Headache Center
    Cephalalgia 20:20-9. 2000
    Migraine patients are characterized by increased amplitude and reduced habituation of contingent negative variation (CNV). Furthermore, the CNV underlies periodic changes during the pain-free interval, being maximal before attack...
  64. ncbi Phonetic mismatch negativity predicts verbal memory deficits in schizophrenia
    Yuki Kawakubo
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Neuroreport 17:1043-6. 2006
    ..These results suggest that electrophysiological auditory sensory memory dysfunction underlies the basis for neuropsychological auditory verbal memory deficits in schizophrenia...
  65. ncbi Specific task anticipation versus unspecific orienting reaction during early contingent negative variation
    Stephan Bender
    Department for Child and Adolescent Psychiatry, Psychiatric Clinic, University of Heidelberg, Blumenstrasse 8, D 69115 Heidelberg, Germany
    Clin Neurophysiol 115:1836-45. 2004
    ..To investigate whether a warning stimulus in a forewarned reaction time task elicits only an unspecific orienting reaction or task specific motor cortex activity...
  66. ncbi Slow cortical potentials in migraine families are associated with psychosocial factors
    Wolf Dieter Gerber
    Institute of Medical Psychology, University of Kiel, Neimannsweg 147, Germany
    J Psychosom Res 52:215-22. 2002
    ..The aim of the study was the determination of the relationships between neurophysiological and psychosocial factors within the pathogenesis of migraine...
  67. ncbi Basal ganglia involvement in sensory and cognitive processing. A depth electrode CNV study in human subjects
    M Bares
    1st Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91, Brno, Czech Republic
    Clin Neurophysiol 112:2022-30. 2001
    ..Intracranial recordings were taken from the basal ganglia (BG) in order to explore the possible role of the BG in the cognitive processing of sensory information...
  68. ncbi Relationship between precipitating agents and neurophysiological abnormalities in migraine
    M Siniatchkin
    Paediatric Neurology, University of Kiel, Kiel, Germany
    Cephalalgia 26:457-65. 2006
    ..The contingent negative variation (CNV) was recorded in the premenstrual and ovulation phases of the cycle in both rest and stress ..
  69. pmc Contingent negative variation as a dopaminergic biomarker: evidence from dose-related effects of methylphenidate
    Anke M W Linssen
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Psychopharmacology (Berl) 218:533-42. 2011
    ..Preparation of a motor response has been associated with dopamine release in the basal ganglia, and response readiness may therefore serve as a pharmacodynamic marker of dopamine activity...
  70. ncbi Topography of CNV and PINV in schizotypal personality
    C Klein
    Department of Psychology, University of Freiburg, Germany
    Psychophysiology 35:272-82. 1998
    ..Scalp amplitude and Laplacian maps of the terminal contingent negative variation (tCNV) and PINV and the time course of the PINV were compared between the two groups...
  71. ncbi Motor processing after movement execution as revealed by evoked and induced activity
    Stephan Bender
    Department for Child and Adolescent Psychiatry, University of Heidelberg, Blumenstrasse 8, D 69115, Germany
    Brain Res Cogn Brain Res 21:49-58. 2004
    ..variation (PINV) in 39 healthy right-handed adolescents in an acoustic forewarned reaction time (contingent negative variation, CNV) task using a 64-electrode high-density sensor array...
  72. ncbi Cortical and subcortical distribution of middle and long latency auditory and visual evoked potentials in a cognitive (CNV) paradigm
    Martin Bares
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Clin Neurophysiol 114:2447-60. 2003
    ..different parts of the human brain as related to a motor task (hand movement) in a cognitive paradigm (Contingent Negative Variation)...
  73. ncbi Migraine--evidence for a disturbance of cerebral maturation in man?
    P Kropp
    Department of Medical Psychology, Center of Nervous Diseases, University of Kiel, Germany
    Neurosci Lett 276:181-4. 1999
    The contingent negative variation (CNV), a slow cortical potential between two defined stimuli, was used to record the effect of age in 162 migraine patients and 320 healthy controls aged between 8 and 59 years...
  74. ncbi Development of preparatory activity indexed by the contingent negative variation in children
    Angélica B Flores
    Human Psychobiology Lab, Departamento de Psicologia Experimental, Facultad de Psicologia, Universidad de Sevilla, C Camilo José Cela S N, Seville, Spain
    Brain Cogn 71:129-40. 2009
    ..The behavioral responses and the contingent negative variation (CNV) generated between S1 (the warning stimulus) and S2 (the imperative stimulus) were compared ..
  75. ncbi Relationship between CNV and timing of an upcoming event
    Micha Pfeuty
    Unité de Neurosciences Cognitives et Imagerie Cérébrale, CNRS UPR 640 LENA Hôpital Pitié Salpêtrière, 47, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Neurosci Lett 382:106-11. 2005
    This study reports an analysis of the Contingent Negative Variation (CNV) recorded on the human scalp during the comparison of a test duration with a previously memorized duration...
  76. ncbi Brain activity relating to the contingent negative variation: an fMRI investigation
    Y Nagai
    Institute of Neurology, Department of Clinical and Experimental Epilepsy, London WC1N 3BG, UK
    Neuroimage 21:1232-41. 2004
    The contingent negative variation (CNV) is a long-latency electroencephalography (EEG) surface negative potential with cognitive and motor components, observed during response anticipation...
  77. ncbi Mismatch negativity (MMN) in multiple sclerosis: an event-related potentials study in 46 patients
    Julien Jung
    Department of Clinical Neurophysiology, Hopital Neurologique, Lyon, France
    Clin Neurophysiol 117:85-93. 2006
    ..To assess pre-attentive detection mechanisms indexed by MMN component of auditory Event-Related Potentials (ERPs) in Multiple Sclerosis (MS) patients...
  78. ncbi Charting the maturation of the frontal lobe: an electrophysiological strategy
    S J Segalowitz
    Brock University, St Catharines, Ont, Canada
    Brain Cogn 55:116-33. 2004
    ..Our analysis of contingent negative variation, error-related negativity, and novelty P300 data show that the ERPs associated with these regions are ..
  79. ncbi Mismatch negativity and N100 in comatose patients
    C Fischer
    Clinical Neurophysiology Unit, EA1880, Neurological Hospital, Mental Process and Brain Activation, Lyon, France
    Audiol Neurootol 5:192-7. 2000
    ..The amplitudes of MMN and N100 in comatose patients were smaller than those of healthy subjects. It is concluded that MMN and N100 can be very useful in predicting whether or not a comatose patient will regain consciousness...
  80. ncbi Dissociation between contingent negative variation (CNV) and Bereitschaftspotential (BP) in patients with parkinsonism
    A Ikeda
    Department of Brain Pathophysiology, Kyoto University School of Medicine, Japan
    Electroencephalogr Clin Neurophysiol 102:142-51. 1997
    In order to clarify the generator mechanism of the late component of contingent negative variation (CNV), we compared the late CNV with Bereitschaftspotential (BP) in patients with parkinsonism (Parkinson's disease and progressive ..
  81. ncbi Reduced sensory anticipation in migraine
    Elles J C M Mulder
    Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Psychophysiology 39:166-74. 2002
    ..This might explain the reduced anticipation, as well as the slow responses during selective attention that we previously reported in these patients...
  82. ncbi Cognitive potentials in the basal ganglia-frontocortical circuits. An intracerebral recording study
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Exp Brain Res 158:289-301. 2004
    ..related to cognitive activities linked with movement preparation: BP (Bereitschaftspotential) and CNV (contingent negative variation)...
  83. ncbi Migraine in childhood--are periodically occurring migraine attacks related to dynamic changes of cortical information processing?
    M Siniatchkin
    Institute of Medical Psychology, Center of Nervous Diseases, University of Kiel, Germany
    Neurosci Lett 279:1-4. 2000
    Amplitudes and habituation of contingent negative variation (CNV) were analyzed in relation to spontaneously occurring migraine attacks in ten children suffering from migraine without aura...
  84. ncbi Implicit, intuitive, and explicit knowledge of abstract regularities in a sound sequence: an event-related brain potential study
    Titia L van Zuijen
    Cognitive Brain Research Unit, University of Helsinki, Finland
    J Cogn Neurosci 18:1292-303. 2006
    ..Intuitive deviant detection was not accompanied by P3 elicitation whereas subjects who developed explicit knowledge of the sound sequence during the training did show a P3 to the detected deviants...
  85. ncbi [Mismatch negativity in schizophrenia research. An indicator of early processing disorders of acoustic information]
    T Rosburg
    Klinik fur Psychiatrie, Friedrich Schiller Universitat Jena, Jena, Deutschland
    Nervenarzt 75:633-41. 2004
    ..Clear evidence for a hemispheric lateralization of the MMN reduction in schizophrenic patients is lacking. A hypofunction of the N-methyl-D-aspartate (NMDA) receptor is discussed as a possible explanation of this deficit...
  86. ncbi Perimenstrual migraine: effect of Estraderm TTS and the value of contingent negative variation and exteroceptive temporalis muscle suppression test
    M G Smits
    Hospital De Gelderse Vallei, Ede, The Netherlands
    Headache 34:103-6. 1994
    ..Clinical neurophysiological tests, contingent negative variation (CNV) and exteroceptive temporalis muscle suppression test (ETST) were performed before treatment...
  87. ncbi Automatic encoding of polyphonic melodies in musicians and nonmusicians
    Takako Fujioka
    Baycrest Centre for Geriatric Care, Canada
    J Cogn Neurosci 17:1578-92. 2005
    ....
  88. ncbi Attention capture by auditory significant stimuli: semantic analysis follows attention switching
    Carles Escera
    Neurodynamics Laboratory, Department of Psychiatry and Clinical Psychobiology, University of Barcelona, P Vall d Hebron 171, 08035 Barcelona, Spain
    Eur J Neurosci 18:2408-12. 2003
    ....
  89. ncbi Contingent negative variation and cognitive performance in hypotension
    M Costa
    Department of Psychology, University of Bologna, Italy
    Psychophysiology 35:737-44. 1998
    ..Attention was examined with contingent negative variation (CNV) recorded using light and tone as S1 and S2...
  90. ncbi High resolution spatiotemporal analysis of the contingent negative variation in simple or complex motor tasks and a non-motor task
    R Q Cui
    Department of Clinical Neurology, University of Vienna, Wahringer Gurtel 18 20, A 1090, Vienna, Austria
    Clin Neurophysiol 111:1847-59. 2000
    ..resolution DC-EEG techniques, it was of great interest to apply similar techniques to the other slow brain potential--contingent negative variation (CNV) of externally-cued movements--with the same motor tasks using the same subjects.
  91. ncbi Prediction of migraine attacks using a slow cortical potential, the contingent negative variation
    P Kropp
    Institute of Medical Psychology, Center of Nervous Diseases, Kiel, Germany
    Neurosci Lett 257:73-6. 1998
    Amplitudes of contingent negative variation (CNV) as a slow cortical potential in migraine patients were recorded before and after migraine attacks...
  92. ncbi Motor circuitry re-organization after pallidotomy in Parkinson disease: a neurophysiological study of the bereitschaftspotential, contingent negative variation, and N30
    A Gironell
    Servei de Neurologia, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Catalonia, Spain
    J Clin Neurophysiol 19:553-61. 2002
    ..Bereitschaftspotential (BP) and N30 were recorded for each hand alternately. Contingent negative variation (CNV) was obtained using a visual Go/no-Go paradigm...
  93. ncbi Preparatory visuo-motor cortical network of the contingent negative variation estimated by current density
    C M Gomez
    Psychobiology Laboratory, Department of Experimental Psychology, University of Sevilla, Spain
    Neuroimage 20:216-24. 2003
    The present report studied the intracerebral current density of the contingent negative variation (CNV) during a visuo-manual task using the gap paradigm. The CNV is usually obtained during preparatory periods for perception and action...
  94. ncbi Event-related potentials to pitch and rise time change in children with reading disabilities and typically reading children
    J A Hämäläinen
    Department of Psychology, University of Jyvaskyla, PO Box 35, Agora, 40014 Jyvaskyla, Finland
    Clin Neurophysiol 119:100-15. 2008
    ..The purpose of the present study was to investigate whether children with reading disabilities (RD) process rise time and pitch changes differently to control children as a function of the interval between two tones...
  95. ncbi Deviance-elicited changes in event-related potentials are attenuated by ketamine in mice
    Richard S Ehrlichman
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cogn Neurosci 20:1403-14. 2008
    ..This study examines a novel rodent model of impaired pitch deviance detection in mice using the NMDA receptor antagonist ketamine...
  96. pmc Brain potentials to sexually suggestive whistles show meaning modulates the mismatch negativity
    Jason Frangos
    Cognitive Electrophysiology Laboratory, NYS Psychiatric Institute, New York, New York, USA
    Neuroreport 16:1313-7. 2005
    ..These data suggest that enhanced mismatch negativity magnitude was due to the semantic valence of the eliciting deviant...
  97. pmc Detecting violations of sensory expectancies following cerebellar degeneration: a mismatch negativity study
    Torgeir Moberget
    Institute of Psychology, University of Oslo, Norway
    Neuropsychologia 46:2569-79. 2008
    ..Periodicity had limited and somewhat inconsistent effects. The present results are at odds with a general role for the cerebellum in sensory prediction and provide partial support for the timing hypothesis...
  98. ncbi Electrophysiological correlates of encoding and retrieving emotional events
    Stefanie Koenig
    Department of Psychology, Saarland University, Saarbruecken, Germany
    Emotion 8:162-73. 2008
    ....
  99. ncbi Effects of visual attentional load on low-level auditory scene analysis
    Benjamin J Dyson
    Department of Psychology, University of Sussex, Falmer, Brighton, England
    Cogn Affect Behav Neurosci 5:319-38. 2005
    ..In Experiment 3, we investigated auditory ERP generation under conditions of no visual task. The results are discussed with respect to a distinction between process-general (N1 and P2) and process-specific (MMN and ORN) auditory ERPs...
  100. pmc The neural organization of semantic memory: Electrophysiological activity suggests feature-based segregation
    Tatiana Sitnikova
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Biol Psychol 71:326-40. 2006
    ..The high temporal resolution of ERPs allowed us to demonstrate that differences in processing animals and tools occurred specifically within the time-window encompassing semantic analysis...
  101. ncbi Movement-related potentials in the Go/NoGo task: the P3 reflects both cognitive and motor inhibition
    Janette L Smith
    School of Psychology, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia
    Clin Neurophysiol 119:704-14. 2008
    ..The contribution of movement-related potentials (MRPs) to the Go/NoGo N2 and P3 'inhibitory' effects is controversial. This study examined these components in overt and covert response inhibition tasks...

Research Grants40

  1. Cortical Preparation for Postural Responses in Parkinson's Disease
    Beth A Smith; Fiscal Year: 2011
    ..More specifically, electroencephalography (EEG) will be used to measure contingent negative variation (CNV), a slow, negative shift in EEG amplitude that occurs prior to cued voluntary movements...
  2. Reliability of Cognitive ERPs in Children and Adults
    Patricia Davies; Fiscal Year: 2006
    ..while performing 3 ERP paradigms: the novelty auditory oddball (an auditory discrimination task), contingent negative variation (a sustained attention task), and the error-related negativity (error-monitoring in simple visual ..
  3. Phencyclidine Abuse & Psychosis: Biomedical Mechanisms
    Daniel C Javitt; Fiscal Year: 2010
    ....
  4. NEUROPHYSIOLOGICAL NMDA DYSFUNCTION IN SCHIZOPHRENIA
    Daniel Javitt; Fiscal Year: 2006
    ..The research will build upon studies currently supported by NIH research and career development awards to the candidate, and will permit the candidate to continue to devote >75 percent effort to research. ..
  5. MECHANISMS OF COGNITIVE DYSFUNCTION IN SCHIZOPHRENIA
    Daniel Javitt; Fiscal Year: 2005
    ..This study will evaluate neurophysiological and neurochemical hypotheses concerning potential etiology of early sensory processing dysfunction in schizophrenia. ..
  6. TREATMENT OF NEGATIVE SYMPTOMS AND COGNITIVE IMPAIRMENTS
    Daniel Javitt; Fiscal Year: 2003
    ..The study will provide new information on the efficacy of d-cycloserine and glycine for both persistent primary and secondary negative symptoms and its effect on cognitive functioning. ..
  7. High-Density ERP mapping & FMRI
    Daniel Javitt; Fiscal Year: 2002
    ..The equipment will also permit monitoring of background EEG during both human and animal studies. Software is requested for state-of-the-art ERP dipole mapping and ERP/MRI co-registration. ..
  8. NEUROIMAGING OF HIV AND COMORBID DISORDERS
    Lance Bauer; Fiscal Year: 2003
    ..An analysis of change scores across groups will permit a formal test of the effects of antiviral treatment on neurophysiological status. ..
  9. Genetic Versus Phenotypic Markers of Relapse Risk
    Lance Bauer; Fiscal Year: 2009
    ....
  10. The Neurodevelopmental Basis of Speech Discrimination
    Valerie Shafer; Fiscal Year: 2009
    ..bilingual) on speech discrimination using brain and behavioral indices of processing of these stimuli. ..
  11. Simultaneous fMRI/ERP of Auditory Change Detection
    Merav Sabri; Fiscal Year: 2005
    ....
  12. Language Systems in Schizophrenia: Behavioral & ERP Data
    Margaret Niznikiewicz; Fiscal Year: 2006
    ..Correlational analyses among the four data sets will seek to characterize the relationships among the four domains of analysis.We predict that females will show less impairment than males on all these measures. ..
  13. Impulsivity and Neural Processing of Rewards
    Laura Martin; Fiscal Year: 2006
    ..abstract_text> ..
  14. Behavioral correlates of fMRI response in cocaine users
    Rita Goldstein; Fiscal Year: 2006
    ..abstract_text> ..
  15. Attentional Bias & Affect in Stress-Vulnerable Smokers
    David Gilbert; Fiscal Year: 2007
    ..An EEG stress response index (alpha asymmetry) will be used in a subgroup of subjects during each of the 3 proposed studies. ..
  16. Sleep and Sleep Disorders in Children
    Dennis Molfese; Fiscal Year: 2007
    ..This is an important first step in minimizing potential negative risks of sleep restriction on cognitive development during the childhood years. ..
  17. MATURATION OF COGNITIVE-RELATED BRAIN POTENTIALS
    David Friedman; Fiscal Year: 2008
    ..The data will be relevant to developmental improvements in cognitive control mechanisms, prefrontal functioning, and episodic memory, and their physiological underpinnings. ..
  18. Complex Sound Processing in the Human Temporal Lobe
    Dana Boatman; Fiscal Year: 2008
    ..Clinical implications include elucidating the relationship between temporal lobe representations of complex sound processing and individual auditory processing abilities. ..
  19. Nicotine Addiction and Reward Processing: An fMRI Investigation
    Laura Martin; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  20. NRT & Bupropion Mechanisms of Efficacy in Smokers
    David G Gilbert; Fiscal Year: 2010
    ..Note,* To avoid final-session mood and arousal effects subjects will actually quit for 67 days, but biobehavioral measures will be collected on the 66 day of abstinence ..
  21. MOLECULAR GENETICS OF OBSESSIVE COMPULSIVE DISORDER
    GREGORY HANNA; Fiscal Year: 2001
    ..Parametric and nonparametric linkage analyses will be performed. Once evidence for linkage between early-onset OCD and a genetic marker is found, more precise gene localization will be pursued. ..
  22. Infant hearing for modulated tones
    Barbara Cone Wesson; Fiscal Year: 2003
    ..This research will also result in methods for assessing threshold sensitivity and sound discrimination in infants that can be applied to those at risk for hearing loss or other auditory dysfunction. ..
  23. Assessment of right hemisphere auditory speech function
    Dana Boatman; Fiscal Year: 2006
    ..Completion of this initial research project will provide the basis for future investigations. ..
  24. DYNAMICS OF BRAIN ACTIVATION DURING MOTOR IMAGERY
    Allen Osman; Fiscal Year: 2004
    ..Further information concerning its less known covert side may lead to unexpected insights about the motor system in general, including its possible roles in cognition. ..
  25. Neonatal Dyslexia Screening Device for Clinical Use
    Dennis Molfese; Fiscal Year: 2004
    ....
  26. Adaptive Regulation of Cognitive Control
    Clay Holroyd; Fiscal Year: 2003
    ..abstract_text> ..
  27. Electrophysiology and Neurocognition in Schizophrenia
    Peter Bachman; Fiscal Year: 2004
    ..abstract_text> ..
  28. Nicotine: Cognition-Affect Interactions
    David Gilbert; Fiscal Year: 2005
    ..The new knowledge derived from these studies will be useful in developing empirical model-based treatment strategies aimed at increasing smoking abstinence. ..
  29. Attentional Mechanisms in Perception and Working Memory
    STEVEN LUCK; Fiscal Year: 2005
    ..abstract_text> ..
  30. NEONATAL PREDICTORS OF LANGUAGE PERFORMANCE
    Dennis Molfese; Fiscal Year: 2001
    ..The goal is to match AER and other assessment data to template data obtained from children with known outcomes so that predictions for referrals can be made and actual outcomes observed. ..
  31. Simultaneous fMRI/ERP measures of Speech Perception
    Einat Liebenthal; Fiscal Year: 2002
    ..Revealing the spatial- temporal organization of speech and nonspeech perception is important for understanding dysfunction underlying specific language impairments. ..
  32. Exercise, Executive Processes and the Aging Brain
    CHARLES HILLMAN; Fiscal Year: 2005
    ....
  33. Error-related brain activity and pediatric anxiety
    Greg Hajcak; Fiscal Year: 2005
    ..It is hypothesized that only the error-related brain activity in pediatric OCD will change over the course of CBT reflecting the post-treatment alteration in the fronto-striatal-thalamic circuitry that underlies OCD. ..
  34. Semantic knowledge and its underlying structures in schizophrenia-an fMRI study
    Margaret Niznikiewicz; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  35. Brain Damage and Recovery of Function in the Adult System
    Mei Fang Cheng; Fiscal Year: 2009
    ..In sum, the present proposal seeks to determine the role of lesion-induced neurogenesis in the context of the recovery of function in the mature dove brain. ..
  36. DEVELOPMENT OF SUSTAINED ATTENTION IN INFANTS
    John Richards; Fiscal Year: 2006
    ....
  37. COGNITIVE AND CEREBROVASCULAR SEQUELAE OF HYPERTENSION
    J Jennings; Fiscal Year: 2004
    ..Successful completion will clarify a) how one major disease of aging reduces intellectual functioning and b) permit a rational choice of clinical regimen to treat this disease while minimizing neuropsychological side effects. ..
  38. AGE-RELATED ERP MEASURES IN ALZHEIMER'S DISEASE
    David Friedman; Fiscal Year: 2004
    ..The data will be relevant to preattentive processing, selective attention based on complex features, age-related pathological changes in these mechanisms, and their physiological underpinnings. ..
  39. DA-NE INTERACTION IN DRUG ABUSE
    Wei Xing Shi; Fiscal Year: 2004
    ..abstract_text> ..