neurobiology

Summary

Top Publications

  1. ncbi Neurobiology of the structure of personality: dopamine, facilitation of incentive motivation, and extraversion
    R A Depue
    Department of Human Development, Laboratory of Neurobiology of Personality and Emotion, Cornell University, Ithaca, NY 14853, USA
    Behav Brain Sci 22:491-517; discussion 518-69. 1999
  2. ncbi Neurobiology, pharmacology, and medicinal chemistry of neuropeptide S and its receptor
    Remo Guerrini
    Department of Pharmaceutical Sciences and Biotechnology Center, University of Ferrara, Ferrara, Italy
    Med Res Rev 30:751-77. 2010
  3. pmc The molecular neurobiology of depression
    Vaishnav Krishnan
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Nature 455:894-902. 2008
  4. pmc The neurobiology of semantic memory
    Jeffrey R Binder
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Trends Cogn Sci 15:527-36. 2011
  5. pmc The neurobiology of decision: consensus and controversy
    Joseph W Kable
    Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuron 63:733-45. 2009
  6. ncbi The neuropathology and neurobiology of traumatic brain injury
    Kaj Blennow
    Clinical Neurochemistry Laboratory, Institue of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Molndal, SE 431 80 Molndal, Sweden
    Neuron 76:886-99. 2012
  7. pmc Apolipoprotein E: from lipid transport to neurobiology
    Paul S Hauser
    Center for Prevention of Obesity, Cardiovascular Disease and Diabetes, Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Prog Lipid Res 50:62-74. 2011
  8. ncbi Structural neurobiology: missing link to a mechanistic understanding of neural computation
    Winfried Denk
    Max Planck Institute for Medical Research, Heidelberg 69120, Germany
    Nat Rev Neurosci 13:351-8. 2012
  9. pmc The novel object recognition memory: neurobiology, test procedure, and its modifications
    M Antunes
    Department of Pharmacology and Pharmacodynamics, Medical University of Lublin, 4A Chodzki St, 20 093, Lublin, Poland
    Cogn Process 13:93-110. 2012
  10. ncbi The neurobiology of Meditation and its clinical effectiveness in psychiatric disorders
    Katya Rubia
    Institute of Psychiatry, Department of Child and Adolescent Psychiatry, King s College University London, UK
    Biol Psychol 82:1-11. 2009

Detail Information

Publications318 found, 100 shown here

  1. ncbi Neurobiology of the structure of personality: dopamine, facilitation of incentive motivation, and extraversion
    R A Depue
    Department of Human Development, Laboratory of Neurobiology of Personality and Emotion, Cornell University, Ithaca, NY 14853, USA
    Behav Brain Sci 22:491-517; discussion 518-69. 1999
    ..Our psychobiological threshold model explains the effects of individual differences in dopamine transmission on behavior, and their relation to personality traits is discussed...
  2. ncbi Neurobiology, pharmacology, and medicinal chemistry of neuropeptide S and its receptor
    Remo Guerrini
    Department of Pharmaceutical Sciences and Biotechnology Center, University of Ferrara, Ferrara, Italy
    Med Res Rev 30:751-77. 2010
    ..The use in future studies of NPSR antagonists will be of paramount importance for understanding which biological functions are controlled by the NPS/NPSR system and for defining the therapeutic potential of selective NPSR ligands...
  3. pmc The molecular neurobiology of depression
    Vaishnav Krishnan
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Nature 455:894-902. 2008
    ..symptoms have been accurately modelled, and these, together with clinical data, are providing insight into the neurobiology of depression...
  4. pmc The neurobiology of semantic memory
    Jeffrey R Binder
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Trends Cogn Sci 15:527-36. 2011
    ....
  5. pmc The neurobiology of decision: consensus and controversy
    Joseph W Kable
    Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuron 63:733-45. 2009
    ..Neurobiological studies of decision making are beginning to enhance our understanding of economic and social behavior as well as our understanding of significant health disorders where people's behavior plays a key role...
  6. ncbi The neuropathology and neurobiology of traumatic brain injury
    Kaj Blennow
    Clinical Neurochemistry Laboratory, Institue of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Molndal, SE 431 80 Molndal, Sweden
    Neuron 76:886-99. 2012
    ..We also consider how the neuropathology and neurobiology of CTE in many ways resembles other neurodegenerative illnesses such as Alzheimer's disease, particularly with ..
  7. pmc Apolipoprotein E: from lipid transport to neurobiology
    Paul S Hauser
    Center for Prevention of Obesity, Cardiovascular Disease and Diabetes, Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Prog Lipid Res 50:62-74. 2011
    ..of apoE as a structural component of circulating plasma lipoproteins has evolved, exciting developments in neurobiology have revitalized interest in apoE...
  8. ncbi Structural neurobiology: missing link to a mechanistic understanding of neural computation
    Winfried Denk
    Max Planck Institute for Medical Research, Heidelberg 69120, Germany
    Nat Rev Neurosci 13:351-8. 2012
    ..Given that the brain's algorithms are ultimately encoded by this network, knowing where all of these connections are should, at the very least, provide the data needed to distinguish between models of neural computation...
  9. pmc The novel object recognition memory: neurobiology, test procedure, and its modifications
    M Antunes
    Department of Pharmacology and Pharmacodynamics, Medical University of Lublin, 4A Chodzki St, 20 093, Lublin, Poland
    Cogn Process 13:93-110. 2012
    ..The purpose of this work was to review the neurobiology and methodological modifications of the test commonly used in behavioral pharmacology.
  10. ncbi The neurobiology of Meditation and its clinical effectiveness in psychiatric disorders
    Katya Rubia
    Institute of Psychiatry, Department of Child and Adolescent Psychiatry, King s College University London, UK
    Biol Psychol 82:1-11. 2009
    ....
  11. ncbi Toward a neurobiology of temporal cognition: advances and challenges
    J Gibbon
    Department of Biopsychology, New York State Psychiatric Institute, Box 50, 722 West 168th Street, New York, NY 10032, USA
    Curr Opin Neurobiol 7:170-84. 1997
    ..Finding the neural substrate of these properties is a major challenge for neurobiology. Recently, advances have been made in our understanding of the brain structures important for timing, ..
  12. pmc Neurobiology of resilience
    Scott J Russo
    Department of Neuroscience, Friedman Brain Institute, Mount Sinai School of Medicine, New York, New York, USA
    Nat Neurosci 15:1475-84. 2012
    ..The therapeutic implications of these findings are important and can pave the way for an innovative approach to drug development for a range of stress-related syndromes...
  13. ncbi Neurobiology of depression
    Eric J Nestler
    Department of Psychiatry and Center for Basic Neuroscience, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Neuron 34:13-25. 2002
    Current treatments for depression are inadequate for many individuals, and progress in understanding the neurobiology of depression is slow...
  14. ncbi A framework for studying the neurobiology of value-based decision making
    Antonio Rangel
    Division of the Humanities and Social Sciences HSS and Computational and Neural Systems Program, California Institute of Technology, Pasadena, California 91125, USA
    Nat Rev Neurosci 9:545-56. 2008
    ..This Review proposes a framework to investigate different aspects of the neurobiology of decision making...
  15. doi Metals in neurobiology: probing their chemistry and biology with molecular imaging
    Emily L Que
    Department of Chemistry, University of California, Berkeley, California 94720, USA
    Chem Rev 108:1517-49. 2008
  16. ncbi The neurobiology of social cognition
    R Adolphs
    The University of Iowa, Department of Neurology, Division of Cognitive Neuroscience, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Opin Neurobiol 11:231-9. 2001
    ..Open questions remain about the domain-specificity of social cognition, about its overlap with emotion and with communication, and about the methods best suited for its investigation...
  17. pmc Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology
    Richard M Ransohoff
    Neuroinflammation Research Center Lerner Research Institute and Mellen Center for MS Treatment and Research Neurological Institute, Cleveland Clinic, Mail Code NC30, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Immunity 31:711-21. 2009
    ..them are the chemokines and their receptors, which play remarkably varied and potent roles in immunobiology and neurobiology. This review limns several illustrative examples and presents general principles of chemokine action that are ..
  18. ncbi Towards the neurobiology of emotional body language
    Beatrice de Gelder
    Cognitive and Affective Neurosciences Laboratory, Tilburg University, 5000 LE Tilburg, The Netherlands
    Nat Rev Neurosci 7:242-9. 2006
    ..This article reviews how whole-body signals are automatically perceived and understood, and their role in emotional communication and decision-making...
  19. ncbi The psychology and neurobiology of addiction: an incentive-sensitization view
    T E Robinson
    Department of Psychology Biopsychology Program, University of Michigan, Ann Arbor 48109, USA
    Addiction 95:S91-117. 2000
    ....
  20. ncbi The physics and neurobiology of magnetoreception
    Sonke Johnsen
    Department of Biology, Duke University, Durham, North Carolina 27708, USA
    Nat Rev Neurosci 6:703-12. 2005
    ..Despite recent advances, however, magnetoreceptors have not been identified with certainty in any animal, and the mode of transduction for the magnetic sense remains unknown...
  21. ncbi Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology
    Christian Grillon
    National Institute of Mental Health, Bethesda, Maryland, USA
    Biol Psychiatry 52:958-75. 2002
    ..Following a brief description of the neurobiology of cued fear and context conditioning, evidence is presented showing that anxious patients are overly sensitive ..
  22. ncbi A common neurobiology for pain and pleasure
    Siri Leknes
    Oxford Centre for Functional MRI of the Brain, Department of Clinical Neurology, Oxford University, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Nat Rev Neurosci 9:314-20. 2008
    ..Understanding the mutually inhibitory effects that pain and reward processing have on each other, and the neural mechanisms that underpin such modulation, is important for alleviating unnecessary suffering and improving well-being...
  23. pmc Neurobiology of economic choice: a good-based model
    Camillo Padoa-Schioppa
    Department of Anatomy and Neurobiology, Washington University in St Louis, St Louis, Missouri 63110, USA
    Annu Rev Neurosci 34:333-59. 2011
    ..The computation and comparison of values may thus take place within these regions...
  24. pmc Speech perception at the interface of neurobiology and linguistics
    David Poeppel
    Department of Linguistics, University of Maryland, College Park, MD 20742, USA
    Philos Trans R Soc Lond B Biol Sci 363:1071-86. 2008
    ..g. temporal primitives) and those primitives derived from linguistic inquiry, to arrive ultimately at a biologically sensible and theoretically satisfying model of representation and computation in speech...
  25. pmc The neurobiology of binge-like ethanol drinking: evidence from rodent models
    Gretchen M Sprow
    Department of Psychology, University of North Carolina, Chapel Hill, NC 27599 3270, USA
    Physiol Behav 106:325-31. 2012
    ..Finally, recent evidence shows that corticotropin-releasing factor (CRF), agouti-related protein (AgRP), neuropeptide Y (NPY), and ghrelin are also implicated as impacting this pattern of ethanol consumption...
  26. ncbi The developmental neurobiology of autism spectrum disorder
    Emanuel DiCicco-Bloom
    Department of Neuroscience, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
    J Neurosci 26:6897-906. 2006
  27. ncbi The neurobiology of aggression and rage: role of cytokines
    Steven S Zalcman
    Department of Psychiatry, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
    Brain Behav Immun 20:507-14. 2006
    ..Present research is designed to further delineate the roles of cytokines in aggressive behavior and to begin to unravel the possible signaling pathways involved this process...
  28. ncbi Drug addiction: the neurobiology of disrupted self-control
    Ruben D Baler
    National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
    Trends Mol Med 12:559-66. 2006
    ..We posit that the time has come to recognize that the process of addiction erodes the same neural scaffolds that enable self-control and appropriate decision making...
  29. ncbi The neurobiology of isoprostanes and Alzheimer's disease
    Domenico Pratico
    Department of Pharmacology, Temple University, School of Medicine, Philadelphia, PA 19140, USA
    Biochim Biophys Acta 1801:930-3. 2010
    ....
  30. pmc Biological sex affects the neurobiology of autism
    Meng Chuan Lai
    Autism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18B, Trumpington Road, Cambridge CB2 8AH, UK
    Brain 136:2799-815. 2013
    ..with autism have thus been relatively overlooked, and have generally been assumed to have the same underlying neurobiology as males with autism...
  31. pmc Further developments in the neurobiology of food and addiction: update on the state of the science
    Nicole M Avena
    Department of Psychiatry, University of Florida, College of Medicine, Gainesville, Florida, USA
    Nutrition 28:341-3. 2012
    ....
  32. pmc The neurobiology of the stress-resistant brain
    Monika Fleshner
    Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    Stress 14:498-502. 2011
    The 2010 Neurobiology of Stress Workshop brought together scientists from all over the world to share and discuss their results from studies examining the consequences of acute, repeated, and chronic stressor exposure on health and ..
  33. pmc The neurobiology of pair bonding: insights from a socially monogamous rodent
    Kimberly A Young
    Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, FL 32306, USA
    Front Neuroendocrinol 32:53-69. 2011
    ..with which they are formed in other mammalian species, we know surprisingly little about their underlying neurobiology. Over the past few decades, the prairie vole (Microtus ochrogaster) has emerged as an animal model of pair ..
  34. pmc Social influences on neurobiology and behavior: epigenetic effects during development
    J P Curley
    Columbia University, Department of Psychology, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Psychoneuroendocrinology 36:352-71. 2011
    ....
  35. ncbi The neurobiology of zinc in health and disease
    Christopher J Frederickson
    NeuroBio Tex, Inc, 101 Christopher Columbus Blvd, Galveston, Texas 77550, USA
    Nat Rev Neurosci 6:449-62. 2005
    ..However, the number of biological functions, health implications and pharmacological targets that are emerging for zinc indicate that it might turn out to be 'the calcium of the twenty-first century'...
  36. pmc Toward a neurobiology of delusions
    P R Corlett
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Centre, Abraham Ribicoff Research Facility, 34 Park Street, New Haven, CT 06519, USA
    Prog Neurobiol 92:345-69. 2010
    ..The present model attempts to provide a framework through which we can build a mechanistic and translational understanding of these puzzling symptoms...
  37. ncbi Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology
    Paul J Harrison
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
    Biol Psychiatry 60:132-40. 2006
    ..Understanding the neurobiology of NRG1 and its involvement in schizophrenia is challenged by the complexity of the gene, which gives rise to ..
  38. ncbi Neurobiology of nicotine addiction: implications for smoking cessation treatment
    Neal L Benowitz
    Division of Clinical Pharmacology and Experimental Therapeutics, Medical Service, San Francisco General Hospital Medical Center, San Francisco, California, USA
    Am J Med 121:S3-10. 2008
    ..Further, given the important role of sensory effects of smoking and psychoactive effects of nicotine, counseling and behavioral therapies are important adjuncts to and substantially augment the benefits of pharmacotherapy...
  39. pmc The neurobiology of anhedonia and other reward-related deficits
    Andre Der-Avakian
    Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA 92093 0603, USA
    Trends Neurosci 35:68-77. 2012
    ..An understanding of anhedonia and other reward-related constructs will facilitate the diagnosis and treatment of disorders that include reward deficits as key symptoms...
  40. ncbi The neurobiology of punishment
    Ben Seymour
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, 12 Queen Square, London WC1X 3BG, UK
    Nat Rev Neurosci 8:300-11. 2007
    ..Here, we review the proximate neurobiological basis of punishment, considering the motivational processes that underlie punishing actions...
  41. ncbi Invertebrate preparations and their contribution to neurobiology in the second half of the 20th century
    Francois Clarac
    P3M, CNRS, Universite de la Mediterranee, Marseille, France
    Brain Res Rev 54:113-61. 2007
    This review summarized the contribution to neurobiology achieved through the use of invertebrate preparations in the second half of the 20th century...
  42. ncbi Counting on neurons: the neurobiology of numerical competence
    Andreas Nieder
    Primate NeuroCognition Laboratory, Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Nat Rev Neurosci 6:177-90. 2005
    ..Neural representations of numerical information can engage extensive cerebral networks, but the posterior parietal cortex and the prefrontal cortex are the key structures in primates...
  43. ncbi Neurobiology of addiction. An integrative review
    Aviel Goodman
    Minnesota Institute of Psychiatry, 1347 Summit Avenue, St Paul, MN 55105, USA
    Biochem Pharmacol 75:266-322. 2008
    ..An integrative review of the literature that addresses the neurobiology of addiction is then presented, organized according to the three functional systems that constitute the ..
  44. ncbi Addiction and the brain: the neurobiology of compulsion and its persistence
    S E Hyman
    National Institute of Mental Health, 6001 Executive Boulevard, Bethesda, Maryland 20892 9669, USA
    Nat Rev Neurosci 2:695-703. 2001
    ..Here we review evidence for the possibility that compulsion and its persistence are based on a pathological usurpation of molecular mechanisms that are normally involved in memory...
  45. ncbi The neurobiology of repetitive behavior: of mice…
    Marieke Langen
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Neurosci Biobehav Rev 35:345-55. 2011
    ..Although the exact nature of these imbalances are not yet fully understood, synthesizing the literature in this area provides a framework for studying the neurobiological systems involved in repetitive behavior...
  46. ncbi Neurobiology of hyperactivity and reward: agreeable restlessness in anorexia nervosa
    Anton J W Scheurink
    Department of Neuroendocrinology, University of Groningen, The Netherlands
    Physiol Behav 100:490-5. 2010
    ..The paper represents an invited review by a symposium, award winner or keynote speaker at the Society for the Study of Ingestive Behavior [SSIB] Annual Meeting in Portland, July 2009...
  47. pmc Neurobiology of rehabilitation
    Bruce H Dobkin
    Department of Neurology, Geffen School of Medicine, University of California Los Angeles, Reed Neurologic Research Center, 710 Westwood Plaza Los Angeles, California 90095 1769, USA
    Ann N Y Acad Sci 1038:148-70. 2004
    ..As clinicians digest the finer details of the neurobiology of rehabilitation, they will translate laboratory data into controlled clinical trials...
  48. ncbi The primate amygdala and the neurobiology of social behavior: implications for understanding social anxiety
    David G Amaral
    Department of Psychiatry, Center for Neuroscience, California Regional Primate Research Center, University of California, 1544 Newton Court, Davis, CA 95616, USA
    Biol Psychiatry 51:11-7. 2002
    ..Finally, recent data from developmental studies raise the possibility that, at least at some developmental stages, fear in social contexts may be subserved by different brain regions than fear of inanimate objects...
  49. pmc Neurobiology of gambling behaviors
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Curr Opin Neurobiol 23:660-7. 2013
    ..Considerations for future directions in gambling research, with a view towards translating neurobiological advances into more effective prevention and treatment strategies, are discussed. ..
  50. pmc Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment
    Christopher Pittenger
    Department of Psychiatry, Yale University School of Medicine, USA
    Pharmacol Ther 132:314-32. 2011
    ....
  51. ncbi Gut memories: towards a cognitive neurobiology of irritable bowel syndrome
    Paul J Kennedy
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Neurosci Biobehav Rev 36:310-40. 2012
    ..With recent advances in neuroimaging technologies, insights into the neurobiology of IBS are beginning to emerge...
  52. pmc Review. Neurobiological mechanisms for opponent motivational processes in addiction
    George F Koob
    Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Philos Trans R Soc Lond B Biol Sci 363:3113-23. 2008
    ....
  53. pmc Fluorescence applications in molecular neurobiology
    Justin W Taraska
    Laboratory of Molecular Biophysics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 66:170-89. 2010
    ..We present the principles of these methods, highlight recent work that uses the methods, and discuss a framework for interpreting results as they apply to molecular neurobiology.
  54. ncbi Understanding the neurobiology of emotion perception: implications for psychiatry
    M L Phillips
    Br J Psychiatry 182:190-2. 2003
  55. ncbi Drosophila melanogaster neurobiology, neuropharmacology, and how the fly can inform central nervous system drug discovery
    Charles D Nichols
    Department of Pharmacology and Experimental Therapeutics, LSU Health Sciences Center, 1901 Perdido St, New Orleans, LA 70112, USA
    Pharmacol Ther 112:677-700. 2006
    ..The promise that the use of model organisms such as the fly offers is speed, high throughput, and dramatically reduced overall costs that together should result in an enhanced rate of discovery...
  56. pmc An interactive visualization tool for multi-channel confocal microscopy data in neurobiology research
    Yong Wan
    Scientific and Imaging Institute, University of Utah, USA
    IEEE Trans Vis Comput Graph 15:1489-96. 2009
    Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure of the nervous system...
  57. ncbi Estrogen receptor neurobiology and its potential for translation into broad spectrum therapeutics for CNS disorders
    Zoe A Hughes
    Wyeth Research, Discovery Neuroscience, Princeton, New Jersey 08543, USA
    Curr Mol Pharmacol 2:215-36. 2009
    ..In particular we will highlight the molecular mechanisms and signal transduction pathways most likely underlying the effects of estrogen in the CNS...
  58. doi Neurobiology with caged calcium
    Graham C R Ellis-Davies
    Department of Pharmacology and Physiology, Drexel University College of Medicine, 245 North 15th Street, Philadelphia, Pennsylvania 19102, USA
    Chem Rev 108:1603-13. 2008
  59. ncbi The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration
    Stephen L Hauser
    Department of Neurology, School of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    Neuron 52:61-76. 2006
    ..Together, these advances have set the stage for the development of therapeutic approaches designed to target the demyelinating and neurodegenerative components of the disease and promote repair...
  60. ncbi Neurobiology of posttraumatic stress disorder
    Christine Heim
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    CNS Spectr 14:13-24. 2009
    ..On the basis of these findings, important hypotheses for developing novel strategies to identify subjects at risk, promote resilience, and devise targets for the prevention or treatment of PTSD can be derived...
  61. ncbi Research review: the neurobiology and genetics of maltreatment and adversity
    Eamon McCrory
    University College London UCL, London, UK The Anna Freud Centre, London, UK
    J Child Psychol Psychiatry 51:1079-95. 2010
    ..Finally we consider several ways in which the neurobiological and genetic research may be relevant to clinical practice and intervention...
  62. ncbi Genetic control of sex differences in C. elegans neurobiology and behavior
    Douglas S Portman
    Department of Biomedical Genetics and Center for Aging and Developmental Biology, University of Rochester, Rochester, New York 14642, USA
    Adv Genet 59:1-37. 2007
    ..Continuing research into the genetic control of neural sex differences in C. elegans is likely to yield insight into conserved mechanisms of cell-autonomous cross talk between cell fate patterning and sexual differentiation pathways...
  63. ncbi Neurobiology of song learning
    Richard Mooney
    Department of Neurobiology, Box 3209, Duke University Medical Center, Durham, NC 27710, United States
    Curr Opin Neurobiol 19:654-60. 2009
    ..This review focuses on recent studies that illuminate the neurobiological mechanisms for singing and song learning...
  64. ncbi Suicide neurobiology
    Carl Ernst
    McGill Group for Suicide Studies, McGill University, Montreal, Quebec, Canada
    Prog Neurobiol 89:315-33. 2009
    In this review, we examine the history of the neurobiology of suicide, as well as the genetics, molecular and neurochemical findings in suicide research...
  65. ncbi Neurobiology of a simple memory
    Donald A Wilson
    Neurobehavioral Institute, Department of Zoology, University of Oklahoma, Norman, Oklahoma 73019, USA
    J Neurophysiol 100:2-7. 2008
    ..This review summarizes recent multidisciplinary analyses of the neurobiology of mammalian odor habituation including in vitro and in vivo synaptic physiology, sensory physiology, ..
  66. pmc Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    Philos Trans R Soc Lond B Biol Sci 363:3181-9. 2008
    ..This paper will review data on the neurobiology of PG, consider its conceptualization as a behavioural addiction, discuss impulsivity as an underlying ..
  67. ncbi The neurobiology of consolidations, or, how stable is the engram?
    Yadin Dudai
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    Annu Rev Psychol 55:51-86. 2004
    ..This debate focuses attention on fundamental issues concerning the nature of the memory trace, its maturation, persistence, retrievability, and modifiability...
  68. pmc Neurobiology of escalated aggression and violence
    Klaus A Miczek
    Department of Psychology, Tufts University, Medford, Massachusetts 02155, USA
    J Neurosci 27:11803-6. 2007
    ....
  69. ncbi Analog versus digital: extrapolating from electronics to neurobiology
    R Sarpeshkar
    Department of Biological Computation, Bell Laboratories, Murray Hill, NJ 07974, USA
    Neural Comput 10:1601-38. 1998
    ....
  70. ncbi Neurobiology of antidepressant withdrawal: implications for the longitudinal outcome of depression
    Brian H Harvey
    Division of Pharmacology, School of Pharmacy, Potchefstroom University for Christian Higher Education, Potchefstroom, South Africa
    Biol Psychiatry 54:1105-17. 2003
    ..Drawing from both clinical and preclinical studies, this article proposes a preliminary molecular perspective and hypothesis on the neuronal implications of adherence to and discontinuation of antidepressant medication...
  71. ncbi Neurobiology in public and private discourse: the case of adults with ADHD
    Christian Bröer
    Department of Sociology and Cultural Anthropology, University of Amsterdam, The Netherlands
    Sociol Health Illn 35:49-65. 2013
    ..b>Neurobiology resonates among adults with ADHD but does not dominate their thinking...
  72. pmc Electrophysiological methods for Caenorhabditis elegans neurobiology
    Miriam B Goodman
    Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California, USA
    Methods Cell Biol 107:409-36. 2012
    ..We also present samples of the cell-intrinsic and postsynaptic ionic currents that can be measured in C. elegans nerves and muscles...
  73. ncbi The neurobiology of temporal lobe epilepsy: too much information, not enough knowledge
    Robert S Sloviter
    Departments of Pharmacology and Neurology, University of Arizona College of Medicine, 1501 N Campbell Avenue, Tucson, AZ 85724, USA
    C R Biol 328:143-53. 2005
    ....
  74. pmc The evolution and comparative neurobiology of endocannabinoid signalling
    Maurice R Elphick
    School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK
    Philos Trans R Soc Lond B Biol Sci 367:3201-15. 2012
    ..Thus, postsynaptic synthesis of 2-AG or anandamide may be a phylogenetically widespread phenomenon, and a variety of proteins may have evolved as presynaptic (or postsynaptic) receptors for endocannabinoids...
  75. ncbi The rhythmic, transverse medullary slice preparation in respiratory neurobiology: contributions and caveats
    Gregory D Funk
    Department of Physiology, 3 020 Katz Bldg, University of Alberta, Edmonton, Alberta, Canada
    Respir Physiol Neurobiol 186:236-53. 2013
    ..precision but more obvious physiological relevance, have clearly established the significance for respiratory neurobiology of the rhythmic slice preparation...
  76. ncbi The neurobiology of social decision-making
    James K Rilling
    Department of Anthropology, Emory University, Atlanta, GA, USA
    Curr Opin Neurobiol 18:159-65. 2008
    ..These studies have begun to elucidate a set of brain regions and neurotransmitter systems involved in decision-making in social interactions...
  77. pmc Clinical progression in Parkinson disease and the neurobiology of axons
    Hsiao Chun Cheng
    Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
    Ann Neurol 67:715-25. 2010
    ..of early involvement of axons in PD has not been adequately emphasized as a rationale to explore the neurobiology of axons for novel therapeutic targets...
  78. ncbi Emotional modulation of multiple memory systems: implications for the neurobiology of post-traumatic stress disorder
    Jarid Goodman
    Department of Psychology, Texas A and M University, College Station, TX 77843, USA
    Rev Neurosci 23:627-43. 2012
    ..We briefly consider the potential role of a stress/anxiety induced habit bias with regard to other psychopathologies,including obsessive-compulsive disorder and drug addiction...
  79. pmc Rationale and consequences of reclassifying obesity as an addictive disorder: neurobiology, food environment and social policy perspectives
    Patricia J Allen
    Department of Psychology, Tufts University, Medford, MA 02155, USA
    Physiol Behav 107:126-37. 2012
    ....
  80. ncbi Research progress on neurobiology of neuronal nitric oxide synthase
    Chun Xia Luo
    Department of Pharmacology, School of Pharmacy, Laboratory of Cerebrovascular Disease, Nanjing Medical University, Nanjing 210029, China
    Neurosci Bull 27:23-35. 2011
    ..nNOS-derived NO is implicated in synapse loss-mediated early cognitive/motor deficits in several neuropathological states, and negatively regulates neurogenesis under physiological and pathological conditions...
  81. ncbi Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia
    Matthijs G Bossong
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Prog Neurobiol 92:370-85. 2010
    ..comprising various neurobiological disciplines, ultimately converging into a model that might explain the neurobiology of cannabis-induced schizophrenia...
  82. ncbi Neurobiology of overeating and obesity: the role of melanocortins and beyond
    Rahul Pandit
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Eur J Pharmacol 660:28-42. 2011
    ..and reward circuitry (the ventral tegmental area and nucleus accumbens) will be evaluated and scrutinized...
  83. ncbi Neurobiology of addiction versus drug use driven by lack of choice
    Serge H Ahmed
    Universite de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, 146 rue Leo Saignat, F 33000 Bordeaux, France
    Curr Opin Neurobiol 23:581-7. 2013
    Research on the neurobiology of addiction often involves nonhuman animals that are given ready access to drugs for self-administration but without other choices...
  84. ncbi Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia
    Jiri Horacek
    Prague Psychiatric Centre, Prague, Czech Republic
    CNS Drugs 20:389-409. 2006
    ..This article summarises the hypothetical mechanisms of action of atypical antipsychotics with respect to the neurobiology of schizophrenia...
  85. ncbi The neurobiology of amyotrophic lateral sclerosis
    André Bento-Abreu
    Laboratory for Neurobiology, Experimental Neurology, K U Leuven, Herestraat, 3000 Leuven, Belgium
    Eur J Neurosci 31:2247-65. 2010
    ....
  86. ncbi Recent advances in stem cell neurobiology
    T Ostenfeld
    MRC Centre for Brain Repair, University of Cambridge, Cambridge, UK
    Adv Tech Stand Neurosurg 28:3-89. 2003
    ..The present chapter aims to review some recent aspects of stem cell research applicable to developmental neurobiology and the potential applications in clinical neuroscience.
  87. ncbi Further insights into the neurobiology of melanin-concentrating hormone in energy and mood balances
    Guillaume J Hervieu
    GlaxoSmithKline R and D, Neurology Centre of Excellence for Drug Discovery, NFSP North, HW1713 Building H17, L1 130 C06 Third Avenue, Harlow, Essex CM19 5AW, UK
    Expert Opin Ther Targets 10:211-29. 2006
    ....
  88. ncbi A microarray gene expression study of the molecular pharmacology of lithium carbonate on mouse brain mRNA to understand the neurobiology of mood stabilization and treatment of bipolar affective disorder
    Andrew McQuillin
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, London, UK
    Pharmacogenet Genomics 17:605-17. 2007
    ..To understand how lithium produces changes in the brain, we studied brain mRNA from 10 mice after treatment with lithium and compared them with 10 untreated controls...
  89. ncbi The neurobiology of repetitive behavior: …and men
    Marieke Langen
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Neurosci Biobehav Rev 35:356-65. 2011
    ..However, studies on the neurobiology of human repetitive behavior have often been limited to distinct conditions and generalization has been ..
  90. ncbi The neurobiology of lipid metabolism in autism spectrum disorders
    Javaneh Tamiji
    Department of Biology, York University, Toronto, Ont, Canada
    Neurosignals 18:98-112. 2010
    ..The existing evidence for the involvement of lipid neurobiology in the pathology of neurodevelopmental disorders such as autism is compelling and opens up an interesting ..
  91. ncbi Neurobiology of decision making: a selective review from a neurocognitive and clinical perspective
    Monique Ernst
    Section of Developmental and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health, 15K North Drive, Bethesda, MD 20892, USA
    Biol Psychiatry 58:597-604. 2005
    ..This approach can be used to follow developmental trajectories of the different stages of decision making and to identify unique deficits associated with distinct psychiatric disorders...
  92. ncbi The molecular and cellular neurobiology of nicotine abuse in schizophrenia
    A Mobascher
    Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
    Pharmacopsychiatry 41:S51-9. 2008
    ....
  93. ncbi Role of inflammation in the neurobiology of stem cells
    Alain R Simard
    Laboratory of Molecular Endocrinology, CHUL Research Center and Department of Anatomy and Physiology, Laval University, 2705 Laurier Blvd, Quebec, Canada G1V 4G2
    Neuroreport 15:2305-10. 2004
    ..It is therefore very important to better understand the role of these newly differentiated microglia before devising therapeutic strategies to either inhibit or improve their recruitment at diseased and injured sites...
  94. ncbi Advances in multidisciplinary and cross-species approaches to examine the neurobiology of psychiatric disorders
    Martien J H Kas
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Eur Neuropsychopharmacol 21:532-44. 2011
    Current approaches to dissect the molecular neurobiology of complex neuropsychiatric disorders such as schizophrenia and major depression have been rightly criticized for failing to provide benefits to patients...
  95. ncbi Studying the neurobiology of social interaction with transcranial direct current stimulation--the example of punishing unfairness
    Daria Knoch
    Institute for Empirical Research in Economics, University of Zurich, 8006 Zurich, Switzerland
    Cereb Cortex 18:1987-90. 2008
    ..Here we show that transcranial direct current stimulation (tDCS) can overcome these limits. We apply right prefrontal cathodal tDCS and show that subjects' propensity to punish unfair behavior is reduced significantly...
  96. ncbi Neurobiology of bipolar disorder
    Andrew R Newberg
    National Institute of Mental Health, 10 Center Drive, MSC 1282, Building 10 CRC, Room 7 5545, Bethesda, MD 20892 1282, USA
    Expert Rev Neurother 8:93-110. 2008
    ....
  97. pmc Alzheimer disease: new concepts on its neurobiology and the clinical role imaging will play
    Clifford R Jack
    Department of Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Radiology 263:344-61. 2012
    ..This presents an important opportunity that, if widely embraced, could greatly expand the application of imaging to improve clinical diagnosis and the quality and efficiency of clinical trials...
  98. pmc Too much of a good thing: neurobiology of non-homeostatic eating and drug abuse
    Rebecca L Corwin
    The Pennsylvania State University, College of Health and Human Development, Nutritional Sciences Department, University Park, 16802, USA
    Physiol Behav 86:5-8. 2005
    ..The various talks illustrated that boundaries need not exist among research fields, and that communication among the various areas enhances the research effort...
  99. pmc Artificial dirt: microfluidic substrates for nematode neurobiology and behavior
    S R Lockery
    Department of Biology, University of Oregon, Eugene, Oregon 97403 1210, USA
    J Neurophysiol 99:3136-43. 2008
    ..of only 302 neurons, the free-living nematode Caenorhabditis elegans is a powerful experimental organism for neurobiology. However, the laboratory substrate commonly used in C...
  100. ncbi Brain iron metabolism: neurobiology and neurochemistry
    Ya Ke
    Department of Physiology, Faculty of Medicine, The Chinese University of Hong Kong, NT, Hong Kong
    Prog Neurobiol 83:149-73. 2007
    ..In the article, the recent advances in studies on neurochemistry and neuropathophysiology of brain iron metabolism were reviewed...
  101. ncbi The neurobiology of social recognition, approach, and avoidance
    Larry J Young
    Department of Psychiatry, Center for Behavioral Neuroscience, Emory University, Atlanta, GA 30322, USA
    Biol Psychiatry 51:18-26. 2002
    ..Here I discuss several rodent models that have been particularly useful in understanding the neurobiology of the discrimination of social verses nonsocial stimuli, affiliative behavior, and social avoidance...

Research Grants75

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  2. NIH Director's Pioneer Award
    Junying Yuan; Fiscal Year: 2009
    ..No Abstract provided ..
  3. NIH Director's Pioneer Award
    ERICH JARVIS; Fiscal Year: 2009
    ..Repairing the pathway in vocal learners, when damaged, would have profound impact for correcting neurological disorders of speech. ..
  4. CRF-Oxytocin Interaction in the Regulation of Stress and Affect
    Joanna Dabrowska; Fiscal Year: 2013
    ..Dr. Young, a world-renowned expert in the neurobiology of oxytocin and social behavior, will provide training in the pharmacology of oxytocin and the oxytocin ..
  5. Neuroimaging abnormalities in major depressive disorder: effect of inflammation
    Jonathan Savitz; Fiscal Year: 2013
    ..c) Under the mentorship of Dr. Drevets, I will deepen my knowledge of the neurobiology of mood disorders and will obtain further training in neuroanatomy, enabling me to better interpret imaging ..
  6. Remodeling Neuronal Chromatin in Mouse Models for Depression
    Schahram Akbarian; Fiscal Year: 2013
    ..that chromatin remodeling mechanisms, including histone modification changes, play an important role for the neurobiology of depressive disorders...
  7. Sex Steroid Hormone Regulation of Drug Reinforcement
    Diane Lebesgue; Fiscal Year: 2012
    ..Over the past 4 years, I investigated the neurobiology of estrogen action in the control of female reproductive function and in neuroprotection following brain insult...
  8. Adenosine and the Basal Forebrain in the Control of Behavioral State
    Robert E Strecker; Fiscal Year: 2012
    ..The overall goal of this proposal is to understand the neurobiology underlying the behavioral/physiological consequences of CSR using a rat model...
  9. Functional Neuroimaging of Individual Differences in Affect and Motivation
    BRIAN JAMES MICKEY; Fiscal Year: 2013
    ..and fellowship at the University of Michigan, during which he was introduced to functional neuroimaging and the neurobiology of mood disorders. He was recently appointed Assistant Professor of Psychiatry at the University of Michigan...
  10. The Role of Astrocytes in Cortical Interneuron Development
    KAREN MULLER SMITH; Fiscal Year: 2013
    ..Smith for an independent research career by providing her with theoretical and knowledge-based training in the neurobiology of psychiatric disorders through formal course work in neuroscience, neurodevelopmental disorders and ..
  11. Epigenetic Analysis of iPS Cell Models of Aging and Alzheimer's Disease
    Bruce A Yankner; Fiscal Year: 2010
    ..This project will bring together a multidisciplinary team with broad expertise in neurobiology, disease biology and genomics from Harvard Medical School, the Dana Farber Cancer Institute and the Broad ..
  12. A Computational Framework for Mapping Long Range Genetic Circuits
    Tolga Tasdizen; Fiscal Year: 2010
    ..nih.gov Establishing a network diagram of the brain is one of the major challenges of modern neurobiology and medicine, particularly a diagram of genetic connectivity...
  13. The function of ATM protein in the biology of the adult neuron CNS:
    Karl Herrup; Fiscal Year: 2013
    ..its intimate association with proteins involved in synaptic vesicle behavior argue that there are facets of the neurobiology of ataxia-telangiectasia that remain to be discovered...
  14. Roles of RhoA/Rho-kinase Signaling in Cavernous Neurons Following Axonal Injury
    TRINITY JUDE BIVALACQUA; Fiscal Year: 2013
    ..to succeed as an independent surgeon scientist integrating the fields of neuroscience, cell signaling, and neurobiology of disease pathogenesis...
  15. MECHANISMS OF DENDRITE MORPHOGENESIS BY THE ANAPHASE-PROMOTING COMPLEX
    ALBERT HONG JAE KIM; Fiscal Year: 2013
    ..as well as academic medical leadership and will be supplemented with seminars in Genetics, Anatomy and Neurobiology, and the Hope Center for Neurological Disorders, as well as presentation of the candidate's research at ..
  16. Research Training in Cardiovascular and Pulmonary Diseases
    S Jamal Mustafa; Fiscal Year: 2012
    ..investigators trained in various disciplines including: Physiology, Pharmacology, Biochemistry, Cell Biology, Neurobiology, Microbiology, Immunology, Exercise Science, Genetics, Molecular Biology, Internal Medicine, Cardiology and ..
  17. Multiple Mechanisms of Nasal Chemoreception
    Diego Restrepo; Fiscal Year: 2012
    ..Am. J. Psychiatry 162, 616-618. Rawson,N.E. (2000). Human olfaction. In The neurobiology of taste and smell, T.E. Finger, W.L. Silver, and D. Restrepo, eds. (New York: Wiley-Liss), pp. 257-284...
  18. Neuroendocrine Mechanisms and Therapeutics in an Animal Model of PTSD
    DAVID MARK DIAMOND; Fiscal Year: 2013
    ..This research will enhance our understanding of the neurobiology of traumatic memory processing and aid in the development of therapeutic treatments for PTSD.
  19. Modulation of Colonic Epithelial Permeability by Sex Hormones
    Muriel Larauche; Fiscal Year: 2013
    ..The candidate will be mentored by Dr. Paul Micevych, Professor in the Department of Neurobiology at UCLA and expert in the sex steroids field, in particular in the cellular and molecular events underlying ..
  20. Genomics of RNA Editing: Identification and Regulation
    Jin Billy Li; Fiscal Year: 2013
    ..depression, suicide, glioma, and cancers, and may have contributed to the evolutionary development of human neurobiology and cognition...
  21. Perinatal Programming of Infant Stress Reactivity and the Atopic Phenotype
    Rosalind J Wright; Fiscal Year: 2013
    ..grown with our increased understanding of the natural history and pathophysiology of atopic disorders and the neurobiology of stress. However, the specific pathways involved remain to be elucidated in human studies...
  22. Vision Sciences Training Grant
    Carol A Mason; Fiscal Year: 2013
    ..will be recruited from several selective graduate programs such as the MD-PhD program, Doctoral Program in Neurobiology and Behavior, and Integrated Program in Cellular, Molecular and Biomedical studies, and by advertisement...
  23. Monoamine Contributions to Neurocircuitry in Eating Disorders
    Walter H Kaye; Fiscal Year: 2013
    ..replicate preliminary data showing that striatal [11C]raclopride and [11C]DASB binding may help to explain the neurobiology responsible for an elevated harm avoidance (a measure of anxiety and inhibition) trait in ED...
  24. Function and Structure Adaptations in Forebrain Development
    PAT R LEVITT; Fiscal Year: 2013
    ..The convergence of the human genetic and biochemical studies in ASD and basic developmental neurobiology suggests that MET signaling is important for the proper assembly of forebrain circuits, with dysregulation ..
  25. Developing Novel Dual CRF-R1/Orexin-1 Receptor Antagonists for Tobacco Dependence
    Belew Mekonnen; Fiscal Year: 2011
    ..the significant roles that Orexin-1 (OX-R1) and Corticotropin-releasing factor receptor-1 (CRF-R1) play in the neurobiology of tobacco addiction and relapse...
  26. Age-dependent microglial responses in hypoxia-ischemia
    PETER A FERRAZZANO; Fiscal Year: 2013
    ..Institute for Clinical and Translational Research in statistics, imaging methods, immunology, and developmental neurobiology. Externships to the Vexler Lab at UCSF and the Clark Lab at the Safar Center for Resuscitation Research will ..
  27. REACTIVE OXYGEN SPECIES: STRESS AND DAMAGE IN OLD MUSCLE
    Susan V Brooks; Fiscal Year: 2012
    ..The addition of Eva Feldman to Project 1 adds a further dimension in the fields of neurobiology and neurology for studies of the timing and interactions among age-related changes motor neurons, muscle fibers,..
  28. Mechanisms and Therapeutics for Rett Syndrome
    Mriganka Sur; Fiscal Year: 2013
    ..Mutations in the X-linked MECP2 (methyl-CpG binding protein 2) gene account for 90% of RTT cases. The neurobiology of MECP2 is fundamental to understanding the mechanisms of RTT and to the identification of therapeutics for ..
  29. Cathepsin L in the Biosynthesis of Enkephalins and beta-Endorphin Opioid Peptides
    Steven J Bark; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): This application will provide training for Dr. Steven Bark in the neurobiology and neurochemistry of peptide neurotransmission using analytical and chemical technologies. With Dr...
  30. Genetic Mapping Of Novel Molecular Players in Itch
    RACHEL BETH BREM; Fiscal Year: 2013
    ..We are two biologists with experience and expertise in sensory neurobiology, genetics, and genomics who seek to identify the genes that drive itch behaviors...
  31. Cerebrospinal fluid proteome mediated signaling in the developing CNS
    Maria Lehtinen; Fiscal Year: 2013
    ..Chris Walsh's lab for my second postdoc, in hopes that comprehensive training in developmental neurobiology during the mentored phase of this award would complement my training in molecular neuroscience, and provide ..
  32. Cerebrospinal fluid proteome mediated signaling in the developing CNS
    Maria Lehtinen; Fiscal Year: 2011
    ..Chris Walsh's lab for my second postdoc, in hopes that comprehensive training in developmental neurobiology during the mentored phase of this award would complement my training in molecular neuroscience, and provide ..
  33. A novel and powerful C. elegans behavioral model of addiction
    Eric A Engleman; Fiscal Year: 2013
    ..Although animal models have begun to provide important information about some aspects of the neurobiology of addiction, an understanding of the basic molecular foundations of addiction remains elusive...
  34. MOLECULAR NEUROBIOLOGY OF DRUG ADDICTION
    Eric J Nestler; Fiscal Year: 2013
    ..requesting funds for the competitive renewal of our Program Project Grant (PPG) from NIDA, entitled Molecular Neurobiology of Drug Addiction...
  35. Modulating Secondary Damage Following Traumatic Brain Injury in the Child
    Stuart H Friess; Fiscal Year: 2013
    ..Margulies, Dr. Friess has developed a comprehensive career development plan of graduate coursework in neurobiology and statistical analysis, as well as workshops, seminars, and journal clubs to ensure his transition to an ..
  36. Effect of Baclofen on Alcohol Cue-Elicited Urges to Drink and Smoke
    GEORGE ANTHONY KENNA; Fiscal Year: 2011
    ..Recent research evidence suggests the involvement of the GABAB receptor in the neurobiology of addictions...
  37. Physiology and structure of prefrontal projections to memory and motor circuits
    Maria Medalla; Fiscal Year: 2013
    ..In particular, the Department of Anatomy and Neurobiology at the School of Medicine is a collaborative scientific environment with a long- standing history of seminal ..
  38. Gastointestinal Hormone Research Core Center
    Chung Owyang; Fiscal Year: 2013
    ..These include 1) Neurobiology in Appetite Control and Visceral Pain, 2) Molecular and Cellular Mechanisms of Inflammation, and 3) Cell Growth ..
  39. Label-Free Chemical Imaging for Biological Applications
    Wei Min; Fiscal Year: 2012
    ..We are applying stimulated radiation to tackle two compelling problems in lipid biology and neurobiology: (1) Genetic screening for fat-regulating genes by chemical imaging...
  40. Molecular-Genetic Dissection of Basal Forebrain Circuitry Regulating Arousal
    PATRICK MICHAEL FULLER; Fiscal Year: 2013
    ..Much of the difficulty in understanding the neurobiology of the BF is related to its high cellular heterogeneity and complex anatomical organization...
  41. CRCNS: Theory and experiment of neural circuit mapping by DNA sequencing
    Anthony M Zador; Fiscal Year: 2013
    ..the synergy between theoretical sciences, novel computational methods, and cutting-edge experiments in cellular neurobiology. The award will provide a unique cross-disciplinary environment for training of young neuroscientists...
  42. NEUROBIOLOGY OF VARICELLA ZOSTER VIRUS
    Donald Gilden; Fiscal Year: 2013
    ....
  43. Role of complement in alpha-synuclein based models of Parkinson disease
    HEATHER ELIZABETH ALLEN; Fiscal Year: 2013
    ..the training plan are experiences that help the PI: 1) gain competence in a variety of techniques integrating neurobiology and immunology, 2) collaborate with other scientists, 3) develop hypothesis-driven research, 4) present data in ..
  44. Examination of Reward Processing in the Treatment of Adolescent Major Depression
    Randy Patrick Auerbach; Fiscal Year: 2013
    ..Further, I will complete a Neurobiology course offered through Harvard Medical School in order to develop a strong foundation regarding neuroanatomy ..
  45. Thrombospondins and other matricellular proteins in tissue organization and homeo
    Joanne E Murphy Ullrich; Fiscal Year: 2010
    ..and genetics and their roles in tissue remodeling, fibrosis, injury and stress responses, development, neurobiology, metabolic regulation, angiogenesis, inflammation, and immunity...
  46. WHOLE SLIDE IMAGING SYSTEM FOR TRANSLATIONAL NEUROSCIENCE
    Jin Moo Lee; Fiscal Year: 2010
    ..and online atlas management will be provided by co-investigators David Van Essen (Department of Anatomy and Neurobiology) and Tao Ju (Department of Computer Science and Engineering)...
  47. Signal transduction in TRPM5-expressing olfactory sensory neurons
    Diego Restrepo; Fiscal Year: 2010
    ..Indeed, there already are close ties between the two groups due to common interests on different aspects of neurobiology. Thus, this FIRCA project would strengthen basic science research and training and therefore will provide a ..
  48. Phosphodiesterase-3B signaling in the Hypothalamus and Obesity
    Abhiram Sahu; Fiscal Year: 2013
    ..Thus understanding the mechanisms behind the development of DIO in rodents may have direct relevance to the neurobiology of human obesity...
  49. Identification of Central Targets of Ghrelin
    Jeffrey M Zigman; Fiscal Year: 2010
    ..An increased understanding of the basic physiology and neurobiology of body weight homeostasis is critical in the prevention and treatment of obesity and related co-morbidities ..
  50. HORMONES: BIOCHEMISTRY AND MOLECULAR BIOLOGY
    MAX ELLIOT GOTTESMAN; Fiscal Year: 2013
    ..and Development, Medicine, Microbiology, Pathology, Pediatrics and Pharmacology as well as the Center for Neurobiology, Institute of Human Nutrition, Naomi Berrie Diabetes Center and the Integrated Program in Cellular, Molecular ..
  51. Functional genetic evolution of human brain and behavior
    Eric J Vallender; Fiscal Year: 2013
    ..This proposal is focused on integrating comparative genetics and molecular evolution with functional neurobiology as a means of generating a better understanding of human neuropsychiatric and addiction disorders and ..
  52. Function of Microtubule Plus-End-Tracking Proteins in the Neuronal Growth Cone
    Laura Anne Lowery; Fiscal Year: 2013
    ..elegans behavior. This work resulted in two papers (including first-author in Journal of Neurobiology). She received her PhD in Biology at MIT under the mentorship of Dr. Hazel Sive...
  53. Placebo Effects in the Treatment of Depression: Cognitive and Neural Mechanisms
    Bret R Rutherford; Fiscal Year: 2013
    ..In addition, investigating the neurobiology of placebo effects has the potential to elucidate the pathophysiology of MDD and the mechanisms of action of ..
  54. CSHL Cell Death Conference
    David J Stewart; Fiscal Year: 2013
    ..field of cell death are a diverse group whose interests span invertebrate to mammalian developmental biology, neurobiology, tumorigenesis, immunology, infectious diseases, biochemistry, cell biology, structural biology, cell cycle ..
  55. Phosphoproteomics of Extinction and Reconsolidation of Drug Memories
    Mary M Torregrossa; Fiscal Year: 2013
    ..The candidate has also published several papers investigating the neurobiology of both drug memory extinction and reconsolidation...
  56. Predictors of Treatment Response Relapse and Recurrence in Major Depression
    W Edward Craighead; Fiscal Year: 2012
    ..At the same time, individuals live and grow within an environment that influences developmental neurobiology, neurochemistry, and patterns of thought, feeling and behavior that further impact their vulnerability to the ..
  57. MENOPAUSAL CHANGES IN HYPOTHALAMUS AND HYPERTENSION SUSCEPTIBILITY
    Teresa A Milner; Fiscal Year: 2013
    ..The proposed studies will provide novel information about the neurobiology of a cardiovascular hypothalamic circuit that is particularly sensitive to fluctuations in hormone levels that ..
  58. Translational Research on Addiction to Palatable Food
    Nicole M Avena; Fiscal Year: 2013
    ..term, I hope to have my own teaching and research laboratory in which I can continue to conduct research on the neurobiology of aberrant feeding behavior using both preclinical and clinical models...
  59. Octopamine Neuroanatomy and Functioning in Fruit Fly Social Behavior
    KYLE LYNN GOBROGGE; Fiscal Year: 2013
    ..Basic research in understanding the neurobiology of aggression has been performed using both invertebrate and vertebrate model systems...
  60. Dendritic Spines on AgRP Neurons as Communication Hubs Controlling Feeding
    Dong Kong; Fiscal Year: 2013
    ..Toward these ends, the candidate is now trained by Dr. Bernardo Sabatini (Prof of Neurobiology, HHMI, Dept...
  61. Neurobiology of Social Support
    CAROL SUE CARTER; Fiscal Year: 2010
    ..In addition, these studies may help us understand neuroendocrine mechanisms underlying child neglect or abuse and why these may differ in males and females. ..
  62. Neuroimmune Factors and Co-Morbid Fear, Depression and Alcohol Consumption
    Michael S Fanselow; Fiscal Year: 2010
    ..in emotion related behavior (Fanselow), stress-induced neuroimmune function (Bradesi &Mayer), and the neurobiology of alcohol (Spigelman)...
  63. A Caribbean Project for Clinical and Basic Neuroscience Research
    EDMUNDO NELSON KRAISELBURD; Fiscal Year: 2011
    ..clinical and basic research development given the pre-existing strengths of programs such as the Institute of Neurobiology, the RCMI Clinical Research Center (CRC), and the Specialized Neuroscience Research Program (SNRP)...
  64. Predictive Smoking Cessation Preclinical Battery
    Daniela Brunner; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Despite great advances in both the understanding of the neurobiology of addiction and the development and approval of smoking cessation therapies, a significant need remains for better smoking ..
  65. MOLECULAR NEUROBIOLOGY OF THE CIRCADIAN CLOCK
    Vincent Cassone; Fiscal Year: 2000
    ..They will provide an excellent model for the study of the molecular mechanisms of melatonin action, which is important in many species of vertebrates including humans. ..
  66. MENTAL HEALTH RESEARCH TRAINING
    Stanley Watson; Fiscal Year: 2003
    The goal of the present application is to provide continued support for training postdoctoral fellows in neurobiology and biological psychiatry with particular emphasis on the biology of mood disorders...
  67. FASEB Summer Research Conference on Retinal Neurobiology and Visual Processing
    Maureen A McCall; Fiscal Year: 2010
    ..by applicant): Summary/Abstract This application requests partial funding for the conference on "Retinal Neurobiology and Visual Processing", administered by the Federation of American Societies for Experimental Biology (FASEB), ..
  68. CSHL Conference on Mouse Development, Genetics and Genomics
    David J Stewart; Fiscal Year: 2010
    ..fields using the mouse as a model system, in particular, in developmental biology, immunology, hematology, neurobiology, and oncology...
  69. Paternal Care, Affiliation and Vasopressin: Mechanisms of Monogamy
    Alexander G Ophir; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): The long-term goal of this research program is to understand the neurobiology of monogamy and the social behaviors that comprise this unique mating system...
  70. BIORAD 2-PHOTON LASER SCANNING MICROSCOPY SYSTEM
    Arnold Kriegstein; Fiscal Year: 1999
    ..of the complex relationship between neural structure and function is central to a wide range of problems in neurobiology research...
  71. NEUROBIOLOGY OF DROSOPHILA CONFERENCE
    David Stewart; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): The planned conference on the "Neurobiology of Drosophila" will convene a group of junior and senior scientists to discuss the latest advances in neurobiology research that are being made ..
  72. 2009 Neurobiology of Drosophila Conference
    David Stewart; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): The planned conference on the "Neurobiology of Drosophila" will convene a group of junior and senior scientists to discuss the latest advances in the neurobiology research that are being made in the ..
  73. CYTOSKELETAL PROTEINS & TROPHIC FACTORS IN AGING
    EDWIN GROLLMAN; Fiscal Year: 1991
    ..the development of research skills needed to become a successful, productive independent investigator in the neurobiology of aging in an academic medicine setting...
  74. MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES
    ROBERT DESNICK; Fiscal Year: 2007
    ..The training is primarily in the fields of genetics and neurobiology as related to MRDD...
  75. Systems and Integrative Neurobiology Training Grant
    William Kristan; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): The purpose of the Systems and Integrative Neurobiology (SAIN) Training Grant is to provide a coherent and diverse training program for students interested in the neuronal basis of ..