plant diseases

Summary

Summary: Diseases of plants.

Top Publications

  1. ncbi The plant immune system
    Jonathan D G Jones
    The Sainsbury Laboratory, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK
    Nature 444:323-9. 2006
  2. ncbi Reactive oxygen species: metabolism, oxidative stress, and signal transduction
    Klaus Apel
    Institute of Plant Sciences, Swiss Federal Institute of Technology, Universitätstr 2, 8092 Zurich, Switzerland
    Annu Rev Plant Biol 55:373-99. 2004
  3. ncbi Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens
    Jane Glazebrook
    Department of Plant Biology, University of Minnesota, St Paul, Minnesota 55108, USA
    Annu Rev Phytopathol 43:205-27. 2005
  4. ncbi Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans
    Brian J Haas
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02141, USA
    Nature 461:393-8. 2009
  5. ncbi MAP kinase signalling cascade in Arabidopsis innate immunity
    Tsuneaki Asai
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 415:977-83. 2002
  6. ncbi Role of plant hormones in plant defence responses
    Rajendra Bari
    The Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Plant Mol Biol 69:473-88. 2009
  7. ncbi Plant pathogens and integrated defence responses to infection
    J L Dangl
    Department of Biology and Curriculum in Genetics, University of North Carolina at Chapel Hill, 27599 3280, USA
    Nature 411:826-33. 2001
  8. ncbi Plant immunity: towards an integrated view of plant-pathogen interactions
    Peter N Dodds
    Commonwealth Scientific and Industrial Research Organisation, Division of Plant Industry, GPO Box 1600, Canberra, Australian Capital Territory 2601, Australia
    Nat Rev Genet 11:539-48. 2010
  9. ncbi Plant stomata function in innate immunity against bacterial invasion
    Maeli Melotto
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Cell 126:969-80. 2006
  10. ncbi The genome sequence of the rice blast fungus Magnaporthe grisea
    Ralph A Dean
    Center for Integrated Fungal Research, North Carolina State University, Raleigh, North Carolina 27695, USA
    Nature 434:980-6. 2005

Research Grants

  1. Ecological dynamics of facultative bacterial pathogens
    JAMES DAVID BEVER; Fiscal Year: 2013
  2. Request for support for the Second International Symposium: Facing the Challenges
    ALEXANDER SIMEON RAIKHEL; Fiscal Year: 2012
  3. ADP-ribosylation in plant-bacteria interactions
    Lori Adams Phillips; Fiscal Year: 2007
  4. MICROBIAL PATHOGENESIS AND HOST DEFENSE CONFERENCE
    TERRI GRODZICKER; Fiscal Year: 1999
  5. Identifying targets for diagnosing oral candidiasis
    David Schofield; Fiscal Year: 2005
  6. Genetics of Programmed Cell Death in Arabidoposis
    Jeffery L Dangl; Fiscal Year: 2010
  7. DISEASE ON NEW HOSTS: MICROBOTRYUM AS A MODEL SYSTEM
    Janis Antonovics; Fiscal Year: 2002
  8. Spiroplasma 16S rDNA in TSE Brain Tissues
    Frank Bastian; Fiscal Year: 2006
  9. Novel Approaches to the Inhibition of Anthrax Toxin
    ANDREW ARTENSTEIN; Fiscal Year: 2003
  10. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010

Detail Information

Publications372 found, 100 shown here

  1. ncbi The plant immune system
    Jonathan D G Jones
    The Sainsbury Laboratory, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK
    Nature 444:323-9. 2006
    ..A detailed understanding of plant immune function will underpin crop improvement for food, fibre and biofuels production...
  2. ncbi Reactive oxygen species: metabolism, oxidative stress, and signal transduction
    Klaus Apel
    Institute of Plant Sciences, Swiss Federal Institute of Technology, Universitätstr 2, 8092 Zurich, Switzerland
    Annu Rev Plant Biol 55:373-99. 2004
    ..Considering recent ROS-induced genome-wide expression analyses, the possible functions and mechanisms for ROS sensing and signaling in plants are compared with those in animals and yeast...
  3. ncbi Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens
    Jane Glazebrook
    Department of Plant Biology, University of Minnesota, St Paul, Minnesota 55108, USA
    Annu Rev Phytopathol 43:205-27. 2005
    ..While the model above seems generally correct, there are exceptions and additional complexities...
  4. ncbi Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans
    Brian J Haas
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02141, USA
    Nature 461:393-8. 2009
    ..infestans genome. This probably plays a crucial part in the rapid adaptability of the pathogen to host plants and underpins its evolutionary potential...
  5. ncbi MAP kinase signalling cascade in Arabidopsis innate immunity
    Tsuneaki Asai
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 415:977-83. 2002
    ..Activation of this MAPK cascade confers resistance to both bacterial and fungal pathogens, suggesting that signalling events initiated by diverse pathogens converge into a conserved MAPK cascade...
  6. ncbi Role of plant hormones in plant defence responses
    Rajendra Bari
    The Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Plant Mol Biol 69:473-88. 2009
    ..Here, we review recent advances made in understanding the role of these hormones in modulating plant defence responses against various diseases and pests...
  7. ncbi Plant pathogens and integrated defence responses to infection
    J L Dangl
    Department of Biology and Curriculum in Genetics, University of North Carolina at Chapel Hill, 27599 3280, USA
    Nature 411:826-33. 2001
    ..We include a few crucial concepts to compare and contrast plant innate immunity with that more commonly associated with animals. There are appreciable differences, but also surprising parallels...
  8. ncbi Plant immunity: towards an integrated view of plant-pathogen interactions
    Peter N Dodds
    Commonwealth Scientific and Industrial Research Organisation, Division of Plant Industry, GPO Box 1600, Canberra, Australian Capital Territory 2601, Australia
    Nat Rev Genet 11:539-48. 2010
    ..These insights suggest novel biotechnological approaches to crop protection...
  9. ncbi Plant stomata function in innate immunity against bacterial invasion
    Maeli Melotto
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Cell 126:969-80. 2006
    ..We provide evidence that supports a model in which stomata, as part of an integral innate immune system, act as a barrier against bacterial infection...
  10. ncbi The genome sequence of the rice blast fungus Magnaporthe grisea
    Ralph A Dean
    Center for Integrated Fungal Research, North Carolina State University, Raleigh, North Carolina 27695, USA
    Nature 434:980-6. 2005
    ..The M. grisea genome has been subject to invasion and proliferation of active transposable elements, reflecting the clonal nature of this fungus imposed by widespread rice cultivation...
  11. ncbi A plant miRNA contributes to antibacterial resistance by repressing auxin signaling
    Lionel Navarro
    Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Science 312:436-9. 2006
    ..Repression of auxin signaling restricts P. syringae growth, implicating auxin in disease susceptibility and miRNA-mediated suppression of auxin signaling in resistance...
  12. ncbi The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization
    Christina A Cuomo
    Broad Institute of the Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA
    Science 317:1400-2. 2007
    ..These regions of genome innovation may result from selection due to interactions of F. graminearum with its plant hosts...
  13. ncbi Housekeeping gene selection for real-time RT-PCR normalization in potato during biotic and abiotic stress
    Nathalie Nicot
    Centre de Recherche Public Gabriel Lippmann, Environment and Biotechnologies Research Unit, 41 rue du Brill, L 4422 Belvaux, Luxembourg
    J Exp Bot 56:2907-14. 2005
    ..The relative quantification of the hsp20.2 gene varied according to the internal control and the number of internal controls used, thus highlighting the importance of the choice of internal controls in such experiments...
  14. ncbi Salicylic Acid, a multifaceted hormone to combat disease
    A Corina Vlot
    Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany
    Annu Rev Phytopathol 47:177-206. 2009
    ..The interaction between the SA signaling pathway and those regulated by other plant hormones and/or defense signals is also discussed...
  15. ncbi Crosstalk between abiotic and biotic stress responses: a current view from the points of convergence in the stress signaling networks
    Miki Fujita
    Gene Discovery Research Group, RIKEN Plant Science Center, 1 7 22 Suehiro cho, Yokohama, Kanagawa 203 0045, Japan
    Curr Opin Plant Biol 9:436-42. 2006
    ....
  16. pmc Independently evolved virulence effectors converge onto hubs in a plant immune system network
    M Shahid Mukhtar
    Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Science 333:596-601. 2011
    ..Thus, pathogens from different kingdoms deploy independently evolved virulence proteins that interact with a limited set of highly connected cellular hubs to facilitate their diverse life-cycle strategies...
  17. ncbi Bacterial disease resistance in Arabidopsis through flagellin perception
    Cyril Zipfel
    Friedrich Miescher Institute for Biomedical Research, PO Box 2543, CH 4002 Basel, Switzerland
    Nature 428:764-7. 2004
    ..tomato DC3000 when it is sprayed on the leaf surface. Thus, flagellin perception restricts bacterial invasion, probably at an early step, and contributes to the plant's disease resistance...
  18. ncbi Plant immunity to insect herbivores
    Gregg A Howe
    Department of Energy Plant Research Laboratory and Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Annu Rev Plant Biol 59:41-66. 2008
    ....
  19. pmc Dynamic evolution of pathogenicity revealed by sequencing and comparative genomics of 19 Pseudomonas syringae isolates
    David A Baltrus
    Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    PLoS Pathog 7:e1002132. 2011
    ..This megaplasmid encodes a type IV secretion system and a diverse set of unknown proteins, which dramatically increases both the genomic content of these strains and the pan-genome of the species...
  20. pmc Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea
    Joelle Amselem
    Unité de Recherche Génomique Info, UR1164, INRA, Versailles, France
    PLoS Genet 7:e1002230. 2011
    ..This resource should facilitate the functional studies designed to better understand what makes these fungi such successful and persistent pathogens of agronomic crops...
  21. ncbi Transcription factors in plant defense and stress responses
    Karam Singh
    CSIRO Plant Industry, Centre for Environmental and Life Sciences, Private Bag 5, Wembly WA 6913, Australia
    Curr Opin Plant Biol 5:430-6. 2002
    ..These studies have also revealed some of the complexity and overlap in the responses to different stresses, and are likely to lead to new ways to enhance crop tolerance to disease and environmental stress...
  22. ncbi Significance of inducible defense-related proteins in infected plants
    L C Van Loon
    Phytopathology, Institute of Environmental Biology, Science Faculty, Utrecht University, 3508 TB Utrecht, The Netherlands
    Annu Rev Phytopathol 44:135-62. 2006
    ....
  23. ncbi Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism
    Pietro D Spanu
    Department of Life Sciences, Imperial College London, London, UK
    Science 330:1543-6. 2010
    ..Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting that most effectors represent species-specific adaptations...
  24. pmc A microRNA superfamily regulates nucleotide binding site-leucine-rich repeats and other mRNAs
    Padubidri V Shivaprasad
    Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom
    Plant Cell 24:859-74. 2012
    ..We propose that this process allows pathogen-inducible expression of NBS-LRR proteins and that it contributes to a novel layer of defense against pathogen attack...
  25. ncbi Networks of WRKY transcription factors in defense signaling
    Thomas Eulgem
    Center for Plant Cell Biology, Department of Botany and Plant Sciences, University of California at Riverside, CA 92521, USA
    Curr Opin Plant Biol 10:366-71. 2007
    ..A key mechanism triggering strong immune responses appears to be based on the inactivation of defense-suppressing WRKY proteins...
  26. pmc Of PAMPs and effectors: the blurred PTI-ETI dichotomy
    Bart P H J Thomma
    Laboratory of Phytopathology, Wageningen University, 6708 PB Wageningen, The Netherlands
    Plant Cell 23:4-15. 2011
    ..We argue that plant resistance is determined by immune receptors that recognize appropriate ligands to activate defense, the amplitude of which is likely determined by the level required for effective immunity...
  27. pmc Antagonistic interaction between abscisic acid and jasmonate-ethylene signaling pathways modulates defense gene expression and disease resistance in Arabidopsis
    Jonathan P Anderson
    Cooperative Research Centre for Tropical Plant Protection, University of Queensland, St Lucia, Queensland, 4072, Australia
    Plant Cell 16:3460-79. 2004
    ....
  28. pmc ABA is an essential signal for plant resistance to pathogens affecting JA biosynthesis and the activation of defenses in Arabidopsis
    Bruce A T Adie
    Departamento de Genética Molecular de Plantas, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Campus Universidad Autonoma, 28049 Madrid, Spain
    Plant Cell 19:1665-81. 2007
    ..The results support a model for ABA affecting JA biosynthesis in the activation of defenses against this oomycete...
  29. pmc Plant immunity requires conformational changes [corrected] of NPR1 via S-nitrosylation and thioredoxins
    Yasuomi Tada
    Department of Biology, Post Office Box 90338, Duke University, Durham, NC 27708, USA
    Science 321:952-6. 2008
    ..Thus, the regulation of NPR1 is through the opposing action of GSNO and TRX. These findings suggest a link between pathogen-triggered redox changes and gene regulation in plant immunity...
  30. pmc Differential innate immune signalling via Ca(2+) sensor protein kinases
    Marie Boudsocq
    Department of Genetics, Harvard Medical School, Center for Computational and Integrative Biology, Massachusetts General Hospital, Massachusetts 02114, USA
    Nature 464:418-22. 2010
    ....
  31. pmc Comparative genomics yields insights into niche adaptation of plant vascular wilt pathogens
    Steven J Klosterman
    USDA ARS, Salinas, California, United States of America
    PLoS Pathog 7:e1002137. 2011
    ....
  32. pmc The predicted secretome of the plant pathogenic fungus Fusarium graminearum: a refined comparative analysis
    Neil A Brown
    Centre for Sustainable Pest and Disease Management, Department of Plant Pathology and Microbiology, Rothamsted Research, Harpenden, Hertfordshire, United Kingdom
    PLoS ONE 7:e33731. 2012
    ..graminearum secreted proteins can be considered to be either species or sequenced strain specific...
  33. ncbi A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence
    Delphine Chinchilla
    Zurich Basel Plant Science Center, Botanical Institute, University of Basel, Hebelstrasse 1, 4056 Basel, Switzerland
    Nature 448:497-500. 2007
    ..Thus, BAK1 is not only associated with developmental regulation through the plant hormone receptor BRI1 (refs 6,7), but also has a functional role in PRR-dependent signalling, which initiates innate immunity...
  34. ncbi Oomycetes, effectors, and all that jazz
    Tolga O Bozkurt
    The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom
    Curr Opin Plant Biol 15:483-92. 2012
    ..In this review, we discuss these and other recent advances and highlight the most important open questions in oomycete effector biology...
  35. pmc ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense
    Oscar Lorenzo
    Departamento de Genética Molecular de Plantas, Centro Nacional de Biotecnología Consejo Superior de Investigaciones Científicas, Campus Universidad Autonoma, 28049 Madrid, Spain
    Plant Cell 15:165-78. 2003
    ....
  36. pmc Translocation of Magnaporthe oryzae effectors into rice cells and their subsequent cell-to-cell movement
    Chang Hyun Khang
    Department of Plant Pathology, Kansas State University, Manhattan, Kansas 66506, USA
    Plant Cell 22:1388-403. 2010
    ..We report robust assays for elucidating the molecular mechanisms that underpin effector secretion into BICs, translocation to the rice cytoplasm, and cell-to-cell movement in rice...
  37. ncbi Regulation and secretion of Xanthomonas virulence factors
    Daniela Büttner
    Genetics Department, Institute of Biology, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    FEMS Microbiol Rev 34:107-33. 2010
    ..In this review, we summarize the current knowledge on the infection strategies and regulatory networks controlling secreted virulence factors from Xanthomonas species...
  38. pmc Finished genome of the fungal wheat pathogen Mycosphaerella graminicola reveals dispensome structure, chromosome plasticity, and stealth pathogenesis
    Stephen B Goodwin
    USDA Agricultural Research Service, Purdue University, West Lafayette, Indiana, United States of America
    PLoS Genet 7:e1002070. 2011
    ..The stealth pathogenesis of M. graminicola probably involves degradation of proteins rather than carbohydrates to evade host defenses during the biotrophic stage of infection and may have evolved from endophytic ancestors...
  39. pmc Obligate biotrophy features unraveled by the genomic analysis of rust fungi
    Sebastien Duplessis
    Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique Nancy Université, Interactions Arbres Micro organismes, Centre de Nancy, 54280 Champenoux, France
    Proc Natl Acad Sci U S A 108:9166-71. 2011
    ..Some of these genomic hallmarks are mirrored in the genomes of other microbial eukaryotes that have independently evolved to infect plants, indicating convergent adaptation to a biotrophic existence inside plant cells...
  40. ncbi The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats
    H Cao
    Department of Botany, Duke University, Durham, North Carolina 27708 1000, USA
    Cell 88:57-63. 1997
    ..syringae in the absence of SAR induction...
  41. ncbi Signal signature and transcriptome changes of Arabidopsis during pathogen and insect attack
    Martin De Vos
    Graduate School Experimental Plant Sciences, Section Phytopathology, Department of Biology, Utrecht Faculty of Science, Utrecht University, P O Box 800 84, 3508 TB Utrecht, The Netherlands
    Mol Plant Microbe Interact 18:923-37. 2005
    ....
  42. ncbi Pathogenicity determinants in smut fungi revealed by genome comparison
    Jan Schirawski
    Department of Organismic Interactions, Max Planck Institute for Terrestrial Microbiology, Karl von Frisch Straße 10, 35043 Marburg, Germany
    Science 330:1546-8. 2010
    ..maydis, we demonstrate a role in virulence for four previously unknown diversity regions. This highlights the power of comparative genomics of closely related species for identification of virulence determinants...
  43. ncbi Pathogenomics of Xanthomonas: understanding bacterium-plant interactions
    Robert P Ryan
    BIOMERIT Research Centre, Department of Microbiology, Biosciences Institute, University College Cork, Ireland
    Nat Rev Microbiol 9:344-55. 2011
    ..In this Review, we discuss the insights that functional and comparative genomic studies are providing into the adaptation of this group of bacteria to exploit the extraordinary diversity of plant hosts and different host tissues...
  44. pmc Signatures of adaptation to obligate biotrophy in the Hyaloperonospora arabidopsidis genome
    Laura Baxter
    School of Life Sciences, Warwick University, Wellesbourne, CV35 9EF, UK
    Science 330:1549-51. 2010
    ..These attributes comprise a genomic signature of evolution toward obligate biotrophy...
  45. pmc Transcriptional profiling reveals novel interactions between wounding, pathogen, abiotic stress, and hormonal responses in Arabidopsis
    Yong Hwa Cheong
    Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720, USA
    Plant Physiol 129:661-77. 2002
    ..These results further dissected the nature of mechanical wounding as a stress signal and identified new genes that may play a role in wounding and other signal transduction pathways...
  46. ncbi How do plants achieve immunity? Defence without specialized immune cells
    Steven H Spoel
    Institute of Molecular Plant Sciences, University of Edinburgh, Edinburgh, EH9 3JR, UK
    Nat Rev Immunol 12:89-100. 2012
    ....
  47. ncbi Biological control of soil-borne pathogens by fluorescent pseudomonads
    Dieter Haas
    Department of Fundamental Microbiology, University of Lausanne, CH 1015 Lausanne, Switzerland
    Nat Rev Microbiol 3:307-19. 2005
    ..Before engaging in these activities, biocontrol bacteria go through several regulatory processes at the transcriptional and post-transcriptional levels...
  48. pmc Phosphorylation of the Nicotiana benthamiana WRKY8 transcription factor by MAPK functions in the defense response
    Nobuaki Ishihama
    Laboratory of Defense in Plant Pathogen Interactions, Graduate School of Bioagricultural Sciences, Nagoya University, Aichi 464 8601, Japan
    Plant Cell 23:1153-70. 2011
    ..Thus, MAPK-mediated phosphorylation of WRKY8 has an important role in the defense response through activation of downstream genes...
  49. pmc Tomato immune receptor Ve1 recognizes effector of multiple fungal pathogens uncovered by genome and RNA sequencing
    Ronnie de Jonge
    Laboratory of Phytopathology, Wageningen University, 6708 PB Wageningen, The Netherlands
    Proc Natl Acad Sci U S A 109:5110-5. 2012
    ..In line with this observation, Ve1 was found to mediate resistance toward F. oxysporum in tomato, showing that this immune receptor is involved in resistance against multiple fungal pathogens...
  50. ncbi Fungal effector proteins
    Ioannis Stergiopoulos
    Wageningen University and Research Center http www php wur nl uk, Laboratory of Phytopathology, 6709 PD Wageningen, The Netherlands
    Annu Rev Phytopathol 47:233-63. 2009
    ..Direct interactions seem to favor point mutations in effector genes, leading to amino acid substitutions, whereas indirect interactions seem to favor jettison of effector genes...
  51. pmc Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense
    Xiuren Zhang
    Laboratory of Plant Molecular Biology, Rockefeller University, New York, New York 10021, USA
    Genes Dev 20:3255-68. 2006
    ..These findings provide insight on the molecular arms race between host antiviral RNA silencing and virus counterdefense...
  52. ncbi Hierarchical action and inhibition of plant Dicer-like proteins in antiviral defense
    Angelique Deleris
    Institut de Biologie Moleculaire des Plantes, CNRS Unité Propre de Recherche UPR 2357, 12, rue du Général Zimmer, 67084 Strasbourg Cedex, France
    Science 313:68-71. 2006
    ..These findings define a molecular framework for studying antiviral silencing and defense in plants...
  53. ncbi Tobacco Rar1, EDS1 and NPR1/NIM1 like genes are required for N-mediated resistance to tobacco mosaic virus
    Yule Liu
    Department of Molecular, Cellular and Developmental Biology, OML 451, Yale University, PO Box 208104, New Haven, CT 06520 8104, USA
    Plant J 30:415-29. 2002
    ....
  54. ncbi The role of abscisic acid in plant-pathogen interactions
    Brigitte Mauch-Mani
    University of Neuchatel, Faculty of Science, Institute of Botany, Biochemistry and Molecular Biology Laboratory, Rue Emile Argand 11, BP 2, 2007 Neuchatel, Switzerland
    Curr Opin Plant Biol 8:409-14. 2005
    ..However, recent research shows that abscisic acid can also be implicated in increasing the resistance of plants towards pathogens via its positive effect on callose deposition...
  55. ncbi A putative ABC transporter confers durable resistance to multiple fungal pathogens in wheat
    Simon G Krattinger
    Institute of Plant Biology, University of Zurich, Zollikerstrasse 107, 8008 Zurich, Switzerland
    Science 323:1360-3. 2009
    ..Alleles of Lr34 conferring resistance or susceptibility differ by three genetic polymorphisms. The Lr34 gene, which functions in the adult plant, stimulates senescence-like processes in the flag leaf tips and edges...
  56. ncbi Catch me if you can: bacterial effectors and plant targets
    Laurent Deslandes
    INRA, Laboratoire des Interactions Plantes Microorganismes, UMR441, F 31326 Castanet Tolosan, France
    Trends Plant Sci 17:644-55. 2012
    ....
  57. ncbi Arabidopsis EDS1 connects pathogen effector recognition to cell compartment-specific immune responses
    Katharina Heidrich
    Max Planck Institute for Plant Breeding Research, Department of Plant Microbe Interactions, D 50829 Cologne, Germany
    Science 334:1401-4. 2011
    ..Thus, EDS1 behaves as an effector target and activated TIR-NB-LRR signal transducer for defenses across cell compartments...
  58. pmc The plant pathogen Pseudomonas syringae pv. tomato is genetically monomorphic and under strong selection to evade tomato immunity
    Rongman Cai
    Department of Plant Pathology, Physiology, and Weed Science, Virginia Tech, Blacksburg, Virginia, United States of America
    PLoS Pathog 7:e1002130. 2011
    ..An additional non-synonymous mutation was identified in flg22 in South American isolates. Therefore, MAMPs are more variable than expected differing even between otherwise almost identical isolates of the same pathogen strain...
  59. ncbi Understanding the functions of plant disease resistance proteins
    Gregory B Martin
    Boyce Thompson Institute for Plant Research and Department of Plant Pathology, Cornell University, Ithaca, New York 14853, USA
    Annu Rev Plant Biol 54:23-61. 2003
    ..New technologies arising from the genomics and proteomics revolution will greatly expand our ability to investigate the role of R proteins in plant disease resistance...
  60. ncbi Resistance gene complexes: evolution and utilization
    S H Hulbert
    Department of Plant Pathology, Kansas State University, Manhattan, Kansas 66506, USA
    Annu Rev Phytopathol 39:285-312. 2001
    ..Genes with durable resistance may interact with conserved pathogen elicitors or condition resistance responses that are independent of specific Avr gene interactions...
  61. ncbi RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis
    David Mackey
    Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA
    Cell 108:743-54. 2002
    ..This may enhance RIN4 activity as a negative regulator of plant defense, facilitating pathogen growth. RPM1 may "guard" against pathogens that use AvrRpm1 and AvrB to manipulate RIN4 activity...
  62. ncbi Complete viral genome sequence and discovery of novel viruses by deep sequencing of small RNAs: a generic method for diagnosis, discovery and sequencing of viruses
    Jan F Kreuze
    Germplasm Enhancement and Crop Improved Division, Applied Biotechnology Laboratory, International Potato Center, Apartado, Lima 12, Peru
    Virology 388:1-7. 2009
    ..The results present a novel approach which cannot only identify known viral pathogens, occurring at extremely low titers, but also novel viruses, without the necessity of any prior knowledge...
  63. ncbi Conserved fungal LysM effector Ecp6 prevents chitin-triggered immunity in plants
    Ronnie de Jonge
    Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, Netherlands
    Science 329:953-5. 2010
    ..This may represent a common strategy of host immune suppression by fungal pathogens, because LysM effectors are widely conserved in the fungal kingdom...
  64. ncbi Cross talk between signaling pathways in pathogen defense
    Barbara N Kunkel
    Department of Biology, Washington University, Campus Box 1137, 1 Brookings Drive, St Louis, Missouri 63130, USA
    Curr Opin Plant Biol 5:325-31. 2002
    ..The SA and JA signaling pathways are mutually antagonistic. This regulatory cross talk may have evolved to allow plants to fine-tune the induction of their defenses in response to different plant pathogens...
  65. ncbi The multifaceted role of ABA in disease resistance
    Jurriaan Ton
    Rothamsted Research, West Common, Harpenden, Herts, AL5 2JQ, UK
    Trends Plant Sci 14:310-7. 2009
    ..Here, we discuss the controversial evidence pointing to either a repression or a promotion of resistance by ABA. Furthermore, we propose a model in which both possibilities are integrated...
  66. pmc The tomato homolog of CORONATINE-INSENSITIVE1 is required for the maternal control of seed maturation, jasmonate-signaled defense responses, and glandular trichome development
    Lei Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 16:126-43. 2004
    ..These findings indicate that the JA/COI1 signaling pathway regulates distinct developmental processes in different plants and suggest a role for JA in the promotion of glandular trichome-based defenses...
  67. ncbi Exploiting knowledge of R/Avr genes to rapidly clone a new LZ-NBS-LRR family of late blight resistance genes from potato linkage group IV
    Anoma A Lokossou
    Wageningen UR Plant Breeding, 6700 AJ Wageningen, The Netherlands
    Mol Plant Microbe Interact 22:630-41. 2009
    ..All four Rpi genes recognize the recently identified RXLR effector PiAVR2...
  68. pmc The WRKY70 transcription factor: a node of convergence for jasmonate-mediated and salicylate-mediated signals in plant defense
    Jing Li
    Department of Biosciences, Division of Genetics, University of Helsinki, FIN 00014 Helsinki, Finland
    Plant Cell 16:319-31. 2004
    ..We suggest that WRKY70 acts as an activator of SA-induced genes and a repressor of JA-responsive genes, integrating signals from these mutually antagonistic pathways...
  69. ncbi Evolving disease resistance genes
    Blake C Meyers
    Delaware Biotechnology Institute, University of Delaware, Newark, Delaware 19714, USA
    Curr Opin Plant Biol 8:129-34. 2005
    ..Diversity within populations is maintained by balancing selection. Analyses of whole-genome sequences have and will continue to provide new insight into the dynamics of resistance gene evolution...
  70. ncbi Priming in systemic plant immunity
    Ho Won Jung
    Department of Molecular Genetics and Cell Biology, University of Chicago, 1103 East 57th Street EBC410, Chicago, IL 60637, USA
    Science 324:89-91. 2009
    ..Furthermore, the predicted secreted protein AZI1 is also important for generating vascular sap that confers disease resistance. Thus, azelaic acid and AZI1 are components of plant systemic immunity involved in priming defenses...
  71. pmc Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens
    Thomas Boller
    Zurich Basel Plant Science Center, Botanical Institute, University of Basel, Hebelstrasse 1, 4056 Basel, Switzerland
    Science 324:742-4. 2009
    ..It turns out that the important contribution of PTI to disease resistance is masked by pathogen virulence effectors that have evolved to suppress it...
  72. ncbi Roles of plant small RNAs in biotic stress responses
    Virginia Ruiz-Ferrer
    Institut de Biologie Moleculaire des Plantes du CNRS, UPR2357, 67084 Strasbourg Cedex, France
    Annu Rev Plant Biol 60:485-510. 2009
    ....
  73. ncbi Varied movement strategies employed by triple gene block-encoding viruses
    Jeanmarie Verchot-Lubicz
    Oklahoma State University, Department of Entomology and Plant Pathology, Stillwater, OK 74078, USA
    Mol Plant Microbe Interact 23:1231-47. 2010
    ..We also suggest areas that might profit from future research on viruses harboring this intriguing arrangement of movement proteins...
  74. ncbi SNARE-protein-mediated disease resistance at the plant cell wall
    Nicholas C Collins
    Sainsbury Laboratory John Innes Centre, Norwich, Norfolk NR4 7UH, UK
    Nature 425:973-7. 2003
    ..Functions associated with SNARE-dependent penetration resistance are dispensable for immunity mediated by race-specific resistance (R) genes, highlighting fundamental differences between these two resistance forms...
  75. pmc Bacteria-responsive microRNAs regulate plant innate immunity by modulating plant hormone networks
    Weixiong Zhang
    Department of Computer Science and Engineering, Washington University in Saint Louis, Campus Box 1045, Saint Louis, MO 63130, USA
    Plant Mol Biol 75:93-105. 2011
    ..We discussed the procedural differences between these techniques that may cause the inconsistency...
  76. ncbi Pathogen effectors target Arabidopsis EDS1 and alter its interactions with immune regulators
    Saikat Bhattacharjee
    Division of Plant Sciences, Christopher S Bond Life Sciences Center and Interdisciplinary Plant Group, University of Missouri, Columbia, MO 65211, USA
    Science 334:1405-8. 2011
    ....
  77. pmc Interaction transcriptome analysis identifies Magnaporthe oryzae BAS1-4 as Biotrophy-associated secreted proteins in rice blast disease
    Gloria Mosquera
    Department of Plant Pathology, Kansas State University, Manhattan, Kansas 66506, USA
    Plant Cell 21:1273-90. 2009
    ....
  78. pmc Multiple plant surface signals are sensed by different mechanisms in the rice blast fungus for appressorium formation
    Wende Liu
    Purdue NWAFU Joint Research Center, Northwest A and F University, Yangling, Shaanxi, China
    PLoS Pathog 7:e1001261. 2011
    ..While MoMsb2 is critical for sensing surface hydrophobicity and cutin monomers, MoSho1 may play a more important role in recognizing rice leaf waxes...
  79. pmc Identification and characterization of MPG1, a gene involved in pathogenicity from the rice blast fungus Magnaporthe grisea
    N J Talbot
    Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907 1392
    Plant Cell 5:1575-90. 1993
    ..Our results suggest that hydrophobins may have a role in the elaboration of infective structures by fungi and may fulfill other functions in fungal phytopathogenesis...
  80. pmc The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense
    Martial Pré
    Institute of Biology Leiden, Clusius Laboratory, Leiden University, 2333 AL Leiden, The Netherlands
    Plant Physiol 147:1347-57. 2008
    ....
  81. ncbi Resistance proteins: molecular switches of plant defence
    Frank Lw Takken
    Plant Pathology, Swammerdam Institute for Life Sciences, University of Amsterdam, PO Box 94062, 1090 GB Amsterdam, The Netherlands
    Curr Opin Plant Biol 9:383-90. 2006
    ..Pathogen recognition triggers nucleotide-dependent conformational changes that might induce oligomerisation, thereby providing a scaffold for activation of downstream signalling components...
  82. ncbi Plant disease resistance genes encode members of an ancient and diverse protein family within the nucleotide-binding superfamily
    B C Meyers
    Department of Vegetable Crops, University of California, Davis 95616, USA
    Plant J 20:317-32. 1999
    ..Sequence inferences suggest that these genes encode a novel class of nucleotide-binding proteins...
  83. pmc Diverse set of microRNAs are responsive to powdery mildew infection and heat stress in wheat (Triticum aestivum L.)
    Mingming Xin
    State Key Laboratory for Agrobiotechnology and Key Laboratory of Crop Heterosis and Utilization MOE and Key Laboratory of Crop Genomics and Genetic Improvement MOA, Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100094, China
    BMC Plant Biol 10:123. 2010
    ..MiRNAs can have large-scale regulatory effects on development and stress response in plants...
  84. ncbi Making sense of hormone crosstalk during plant immune responses
    Steven H Spoel
    Department of Biology, P O Box 90338, Duke University, Durham, NC 27708, USA
    Cell Host Microbe 3:348-51. 2008
    ..Here we discuss the various roles that crosstalk may play in response to pathogens with different infection strategies...
  85. ncbi Licensed to kill: the lifestyle of a necrotrophic plant pathogen
    Jan A L van Kan
    Wageningen University, Laboratory of Phytopathology, Binnenhaven 5, 6709 PD Wageningen, The Netherlands
    Trends Plant Sci 11:247-53. 2006
    ..Our increasing understanding of the tools used by a necrotrophic fungal pathogen to invade plants will be instrumental to designing rational strategies for disease control...
  86. ncbi Under pressure: investigating the biology of plant infection by Magnaporthe oryzae
    Richard A Wilson
    School of Biosciences, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter, United Kingdom
    Nat Rev Microbiol 7:185-95. 2009
    ..oryzae. We also look ahead to the key questions that need to be addressed to provide a better understanding of the molecular processes that lead to plant disease and the prospects for sustainable control of rice blast...
  87. ncbi Plant pathogenesis-related (PR) proteins: a focus on PR peptides
    Jan Sels
    Centre of Microbial and Plant Genetics, Katholieke Universiteit Leuven, Kasteelpark Arenberg 20, B 3001 Heverlee, Belgium
    Plant Physiol Biochem 46:941-50. 2008
    ..Finally an update is provided on the potential role of these PR peptides in A. thaliana, with a focus on their possible involvement in plant defense...
  88. pmc Effector genomics accelerates discovery and functional profiling of potato disease resistance and phytophthora infestans avirulence genes
    Vivianne G A A Vleeshouwers
    Wageningen UR Plant Breeding, Wageningen, The Netherlands
    PLoS ONE 3:e2875. 2008
    ..Our findings indicate that effector genomics enables discovery and functional profiling of late blight R genes and Avr genes at an unprecedented rate and promises to accelerate the engineering of late blight resistant potato varieties...
  89. ncbi Transcriptional reprogramming regulated by WRKY18 and WRKY40 facilitates powdery mildew infection of Arabidopsis
    Shree P Pandey
    Department of Plant Microbe Interaction, Max Planck Institute for Plant Breeding Research, Carl von Linne Weg 10, Cologne 50829, Germany
    Plant J 64:912-23. 2010
    ....
  90. pmc Effector-mediated suppression of chitin-triggered immunity by magnaporthe oryzae is necessary for rice blast disease
    Thomas A Mentlak
    School of Biosciences, University of Exeter, Geoffrey Pope Building, Exeter EX4 4QD, United Kingdom
    Plant Cell 24:322-35. 2012
    ..oryzae to cause rice blast disease in the absence of Slp1. We propose that Slp1 sequesters chitin oligosaccharides to prevent PAMP-triggered immunity in rice, thereby facilitating rapid spread of the fungus within host tissue...
  91. pmc Microbiology of the phyllosphere
    Steven E Lindow
    Department of Plant and Microbial Biology, University of California, Berkeley 94720, USA
    Appl Environ Microbiol 69:1875-83. 2003
  92. ncbi A bacterial virulence protein suppresses host innate immunity to cause plant disease
    Kinya Nomura
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA
    Science 313:220-3. 2006
    ..HopM1 mediates the destruction of AtMIN7 via the host proteasome. Our results illustrate a strategy by which a bacterial pathogen exploits the host proteasome to subvert host immunity and causes infection in plants...
  93. pmc Internalization of flax rust avirulence proteins into flax and tobacco cells can occur in the absence of the pathogen
    Maryam Rafiqi
    Division of Plant Science, Research School of Biology, College of Medicine, Biology, and Environment, Australian National University, Canberra, Australian Capital Territory 0200, Australia
    Plant Cell 22:2017-32. 2010
    ..Uptake of these proteins is dependent on signals in their N-terminal regions, but the primary sequence features of these uptake regions are not conserved between different rust effectors...
  94. pmc Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein
    Jacinthe Azevedo
    Institut de Biologie Moleculaire des Plantes du CNRS, Universite de Strasbourg, 67084 Strasbourg Cedex, France
    Genes Dev 24:904-15. 2010
    ..The likely widespread occurrence and expected consequences of GW protein mimicry on host silencing pathways are discussed in the context of innate and adaptive immunity in plants and metazoans...
  95. pmc NB-LRR proteins: pairs, pieces, perception, partners, and pathways
    Timothy K Eitas
    Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA
    Curr Opin Plant Biol 13:472-7. 2010
    ..Importantly, distinct fragments of different NB-LRRs are sufficient for function. Finally, we describe the new roles of accessory proteins and downstream host genes in NB-LRR signaling...
  96. pmc A unique wheat disease resistance-like gene governs effector-triggered susceptibility to necrotrophic pathogens
    Justin D Faris
    Cereal Crops Research Unit, Northern Crop Science Laboratory, US Department of Agriculture Agricultural Research Service, Fargo, ND 58102, USA
    Proc Natl Acad Sci U S A 107:13544-9. 2010
    ..This work suggests that these necrotrophic pathogens may thrive by subverting the resistance mechanisms acquired by plants to combat other pathogens...
  97. pmc The transmission efficiency of tomato yellow leaf curl virus by the whitefly Bemisia tabaci is correlated with the presence of a specific symbiotic bacterium species
    Yuval Gottlieb
    Agricultural Research Organization, Institute of Plant Protection, Department of Entomology, Volcani Center, Bet Dagan 50250, Israel
    J Virol 84:9310-7. 2010
    ..The other symbionts from both biotypes do not seem to be involved in transmission of this virus...
  98. pmc From Guard to Decoy: a new model for perception of plant pathogen effectors
    Renier A L van der Hoorn
    Plant Chemetics Lab, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany
    Plant Cell 20:2009-17. 2008
    ..We discuss the differences between the Guard and Decoy Models and their variants, hypothesize how decoys might have evolved, and suggest ways to challenge the Decoy Model...
  99. ncbi Shades of gray: the world of quantitative disease resistance
    Jesse A Poland
    Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA
    Trends Plant Sci 14:21-9. 2009
    ..We propose that a new generation of genetic resources, complemented by careful phenotypic analysis, will produce a deeper understanding of plant defense and more effective utilization of natural resistance alleles...
  100. pmc Activation of the indole-3-acetic acid-amido synthetase GH3-8 suppresses expansin expression and promotes salicylate- and jasmonate-independent basal immunity in rice
    Xinhua Ding
    National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research Wuhan, Huazhong Agricultural University, Wuhan 430070, China
    Plant Cell 20:228-40. 2008
    ..Both enhanced resistance and abnormal development may be caused by inhibition of the expression of expansins via suppressed auxin signaling...
  101. pmc A germin-like protein gene family functions as a complex quantitative trait locus conferring broad-spectrum disease resistance in rice
    Patricia M Manosalva
    Bioagricultural Sciences and Pest Management, Colorado State University, Fort Collins, Colorado 80523 1177, USA
    Plant Physiol 149:286-96. 2009
    ..Natural selection may have preserved a whole gene family to provide a stepwise, flexible defense response to pathogen invasion...

Research Grants16

  1. Ecological dynamics of facultative bacterial pathogens
    JAMES DAVID BEVER; Fiscal Year: 2013
    Many animal and plant diseases, such as the human diseases cholera, typhoid fever, and legionelliosis, are caused by facultative bacterial pathogens, that exist and proliferate outside the host environment...
  2. Request for support for the Second International Symposium: Facing the Challenges
    ALEXANDER SIMEON RAIKHEL; Fiscal Year: 2012
    ..symposium is that it combines, at a single venue, vector biologists who work on arthropod vectors of human and plant diseases (funding for the latter coming from a separate NSF proposal) thereby allowing participants to find ..
  3. ADP-ribosylation in plant-bacteria interactions
    Lori Adams Phillips; Fiscal Year: 2007
    ..3) The role of endogenous poly(ADP-ribosyl)ation in plant defense and HR cell death will be investigated. Plant diseases threaten human sustenance and serve as an informative model for host-pathogen interactions research...
  4. MICROBIAL PATHOGENESIS AND HOST DEFENSE CONFERENCE
    TERRI GRODZICKER; Fiscal Year: 1999
    ..The integration of a wide variety of aspects of bacterial and fungal pathogenesis, animal and plant diseases, and the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved ..
  5. Identifying targets for diagnosing oral candidiasis
    David Schofield; Fiscal Year: 2005
    ..Since Candida species are the most important fungal pathogen of the oral cavity, the rapid and accurate diagnosis of oral candidiasis using novel disease biomarkers will significantly improve oral health. ..
  6. Genetics of Programmed Cell Death in Arabidoposis
    Jeffery L Dangl; Fiscal Year: 2010
    ..This is the first definition of a function for these proteins, and allows us to propose a detailed characterization of their action as positive cell death regulators. ..
  7. DISEASE ON NEW HOSTS: MICROBOTRYUM AS A MODEL SYSTEM
    Janis Antonovics; Fiscal Year: 2002
    ..Determine the role of genetic factors in the transmission of a pathogen to a new host, c. Determine the role of pathogen specialization in persistence on new hosts. ..
  8. Spiroplasma 16S rDNA in TSE Brain Tissues
    Frank Bastian; Fiscal Year: 2006
    ..involved. Although the role of Spiroplasma in TSE cannot be determined from these experiments, the presence of this microbe in all cases of TSE and not in controls would provide the basis for developing a test for TSE ..
  9. Novel Approaches to the Inhibition of Anthrax Toxin
    ANDREW ARTENSTEIN; Fiscal Year: 2003
    ....
  10. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  11. P. Aeruginosa Biofilms and Burn Wound Infections
    Karin Sauer; Fiscal Year: 2006
    ..aeruginosa pathogenesis and by identifying virulence factors that may be targeted for therapeutic intervention. ..
  12. Rhabdovirus phosphoproteins: RNA silencing and complex formation
    Michael Goodin; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  13. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  14. The molecular basis of morphological evolution
    David L Stern; Fiscal Year: 2010
    ..This detailed analysis of gene regulation promises to provide new insights into how gene regulation functions and evolves in natural species to cause possibly adaptive changes in morphology. ..
  15. P. aeruginosa biofilm specific proteins and regulators
    Karin Sauer; Fiscal Year: 2007
    ..Findings from this research are intended to lead to novel and more effective approaches for the treatment of such biofilm infections. [unreadable] [unreadable] [unreadable] [unreadable]..
  16. GPCR signaling cascades in Cryptococcus neoformans
    Joseph Heitman; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..