- Amplitude, area and duration of the compound muscle action potential change in different ways over the length of the ulnar nerve
Department of Clinical Neurophysiology, Aarhus University Hospital, DK 8000 Aarhus, Denmark
Clin Neurophysiol 117:2085-92. 2006
..To study physiological changes of the compound muscle action potential (CMAP) obtained from stimulation at different sites over the full length of a motor nerve and to study possible effects of anthropometrical factors...
- Correlations of nerve conduction measures in axonal and demyelinating polyneuropathies
Department of Clinical Neurophysiology, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Aarhus C, Denmark
Clin Neurophysiol 118:2383-92. 2007
- Ascorbic acid for Charcot-Marie-Tooth disease type 1A in children: a randomised, double-blind, placebo-controlled, safety and efficacy trial
Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, and Institute for Neuromuscular Research, Children s Hospital at Westmead, Sydney, NSW, Australia
Lancet Neurol 8:537-44. 2009
..We tested the efficacy and safety of ascorbic acid supplementation in children with CMT1A...
- Neurophysiological and neuropathological characterization of new murine models of chemotherapy-induced chronic peripheral neuropathies
V A Carozzi
Department of Neuroscience and Biomedical Technologies, University of Milano Bicocca, Monza MI, Italy
Exp Neurol 226:301-9. 2010
..These results confirm the possibility to use our models to combine the study of the antineoplastic activity of anticancer drugs and of their toxic effects on the peripheral nervous system in the BALB/c mouse strain...
- Charcot-Marie-Tooth disease subtypes and genetic testing strategies
Anita S D Saporta
Department of Neurology, Wayne State University, Detroit, MI, USA
Ann Neurol 69:22-33. 2011
..Identifying the genetic cause of CMT is often necessary for family planning, natural history studies, and for entry into clinical trials. However genetic testing can be both expensive and confusing to patients and physicians...
- Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation
J D England
Neurology 64:199-207. 2005
..The inclusion of this formalized case definition in clinical and epidemiologic research studies will ensure greater consistency of case selection...
- Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial (DCCT) on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interventions and Complications (EDIC) Study
James W Albers
Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan, USA
Diabetes Care 33:1090-6. 2010
- Prevalence of carpal tunnel syndrome in a general population
Department of Orthopedics, Hässleholm Kristianstad Hospital, Sweden
JAMA 282:153-8. 1999
..Although high prevalence rates of CTS in certain occupations have been reported, little is known about its prevalence in the general population...
- The spectrum of neuropathy in diabetes and impaired glucose tolerance
C J Sumner
Department of Neurology, The Johns Hopkins University, Baltimore, MD, USA
Neurology 60:108-11. 2003
..To compare the neuropathy associated with impaired glucose tolerance (IGT) and diabetes mellitus (DM) determined by oral glucose tolerance testing (OGTT)...
- Increased prevalence of impaired glucose tolerance in patients with painful sensory neuropathy
J R Singleton
Division of Neuromuscular Disease, Department of Neurology, University of Utah, Salt Lake City, Utah 84132, USA
Diabetes Care 24:1448-53. 2001
- Signs and symptoms versus nerve conduction studies to diagnose diabetic sensorimotor polyneuropathy: Cl vs. NPhys trial
Peter J Dyck
Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Muscle Nerve 42:157-64. 2010
..Study physician dx from signs and symptoms were excessively variable, often overestimating DSPN. Specific approaches to improving clinical proficiency should be tested...
- Functional trade-offs in white matter axonal scaling
Samuel S H Wang
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
J Neurosci 28:4047-56. 2008
..The heterogeneous white matter composition found in large brains thus reflects a metabolically constrained trade-off that reduces both volume and conduction time...
- Maximum number of collaterals developed by one axon during peripheral nerve regeneration and the influence of that number on reinnervation effects
Bao Guo Jiang
Department of Orthopedics and Trauma, Peking University People s Hospital, Beijing, China
Eur Neurol 58:12-20. 2007
..7 and 18.6 +/- 4.3 m/s, -80.2 +/- 7.1 and 12.7 +/- 3.7 m/s, and -85.4 +/- 5.7 and 10.5 +/- 3.9 m/s, respectively. It has been suggested that 1 axon can regenerate and maintain up to 3 or 4 collaterals in regenerated rat peripheral nerve...
- Acrolein induces myelin damage in mammalian spinal cord
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA
J Neurochem 117:554-64. 2011
..From this data, it is clear that acrolein is capable of inflicting myelin damage as well as axonal degeneration, and may represent an important factor in the pathogenesis in multiple sclerosis and spinal cord injury...
- Neuregulin 1-erbB signaling is necessary for normal myelination and sensory function
Division of Neuroscience, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
J Neurosci 26:3079-86. 2006
..These results suggest that disruption of the NRG1-erbB signaling pathway could contribute to the pathogenesis of peripheral neuropathies with hypomyelination and neuropathic pain...
- Impaired neurovascular repair in subjects with diabetes following experimental intracutaneous axotomy
Gigi J Ebenezer
Department of Neurology, Johns Hopkins University, Baltimore, MD 21287 7609, USA
Brain 134:1853-63. 2011
..These models are useful tools for the efficient investigation of neurotrophic and regenerative drugs, and also to explore factors that may differentially affect axonal regeneration...
- Evaluation of atrophy of foot muscles in diabetic neuropathy -- a comparative study of nerve conduction studies and ultrasonography
Department of Neurology, Aarhus University Hospital, 8000 Aarhus C, Denmark
Clin Neurophysiol 118:2172-5. 2007
..To evaluate the relation between the findings at nerve conduction studies and the size of small foot muscles determined by ultrasonography...
- Nociceptors: a phylogenetic view
Ewan St John Smith
Department of Neuroscience, Max Delbruck Center for Molecular Medicine, 13125 Berlin Buch, Germany
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 195:1089-106. 2009
..This review will focus on what is known about nociceptors throughout the Animalia kingdom and what similarities exist across phyla; especially at the molecular level of ion channels...
- Modeling nerve conduction criteria for diagnosis of diabetic polyneuropathy
Peter J Dyck
Peripheral Neuropathy Research Laboratory, Department of Neurology Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Muscle Nerve 44:340-5. 2011
..In this study we aimed to determine which criteria are valid for nerve conduction (NC) diagnosis of typical diabetic sensorimotor polyneuropathy (DSPN)...
- Bridging small-gap peripheral nerve defects using biodegradable chitin conduits with cultured schwann and bone marrow stromal cells in rats
Department of Orthopaedics and Trauma, Peking University People s Hospital, Beijing, China
J Reconstr Microsurg 21:565-71. 2005
- Elevated glycosylated hemoglobin is associated with subclinical neuropathy in neurologically asymptomatic diabetic patients: a prospective study
Department of Neurosciences, Jordan University of Science and Technology, Irbid, Jordan
J Clin Neurophysiol 26:50-3. 2009
..Therapies for diabetic neuropathy should target the early stages of the disease...
- Information processing in the axon
Equipe INSERM AVENIR, Plasticité de l excitabilité neuronale, Neurobiologie des Canaux Ioniques INSERM U641, Institut Federatif de Recherche Jean Roche, Universite de la Mediterranee, Marseille, France
Nat Rev Neurosci 5:304-16. 2004
- Low peripheral nerve conduction velocities and amplitudes are strongly related to diabetic microvascular complications in type 1 diabetes: the EURODIAB Prospective Complications Study
School of Public Health, Aarhus University, Aarhus, Denmark
Diabetes Care 33:2648-53. 2010
..Because subjective or clinical indicators of neuropathy do not always match well with the presence of abnormal nerve physiology tests, we evaluated associations to nerve conduction in patients with type 1 diabetes...
- Aldose reductase inhibitors in the treatment of diabetic peripheral neuropathy: a review
Kate E Schemmel
Mercy Medical Center, Dubuque, IA 52001, USA
J Diabetes Complications 24:354-60. 2010
..The purpose of this article was to examine how aldose reductase (AR) inhibitors are used in the prevention and treatment of peripheral neuropathy in diabetes, specifically focusing on efficacy...
- Beneficial effects of exendin-4 on experimental polyneuropathy in diabetic mice
Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Japan
Diabetes 60:2397-406. 2011
..The therapeutic potential of exendin-4, an agonist of the glucagon-like peptide-1 receptor (GLP-1R), on diabetic polyneuropathy (DPN) in streptozotocin (STZ)-induced diabetic mice was investigated...
- A novel method of eliciting pain-related potentials by transcutaneous electrical stimulation
University of Essen, Department of Neurology, Germany
Headache 46:1511-7. 2006
..These methods are, however, partly invasive, expensive, and therefore not available for broad clinical use. We recently proposed a novel technique of noninvasive transcutaneous electrical stimulation...
- An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome
Department of Clinical Neurophysiology, Hospital Luterano, Universidade Luterana do Brasil, RS, Porto Alegre, Brazil
Clin Neurophysiol 113:1429-34. 2002
- Axonal ion channels from bench to bedside: a translational neuroscience perspective
Arun V Krishnan
Translational Neuroscience Facility, University of New South Wales, Randwick, Sydney, NSW, Australia
Prog Neurobiol 89:288-313. 2009
- Reliability and validity of the CMT neuropathy score as a measure of disability
M E Shy
Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Neurology 64:1209-14. 2005
..To determine the validity and reliability of the Charcot-Marie-Tooth disease (CMT) neuropathy score (CMTNS) in patients with inherited neuropathy...
- Carpal tunnel syndrome
Department of Surgery, Level 2, Belfast HSC Trust, Lisburn Road, Belfast BT9 7AB, United Kingdom
Ulster Med J 77:6-17. 2008
..Apart from early recovery and return to work there is no significant difference in terms of early and late complications and long-term pain relief between endoscopic and open carpal tunnel surgery...
- Motor unit recruitment strategies investigated by surface EMG variables
Centro di Bioingegneria, Department of Electronics, Politecnico di Torino, Torino 10129, Italy
J Appl Physiol (1985) 92:235-47. 2002
..Our results do not support the establishment of a general relationship between spectral EMG variables and torque or recruitment strategy...
- Acute tetrodotoxin-induced neurotoxicity after ingestion of puffer fish
Matthew C Kiernan
Prince of Wales Medical Research Institute, University of New South Wales, Barker Street, Randwick, Sydney NSW 2031, Australia
Ann Neurol 57:339-48. 2005
..It demonstrates the ability of noninvasive nerve excitability studies to detect Na(+) channel blockade in vivo and also the utility of mathematical modeling to aid interpretation of altered excitability properties in disease...
- A case-control study of obesity as a risk factor for carpal tunnel syndrome in a population of 600 patients presenting for independent medical examination
S P Stallings
Department of Surgery, University of Louisville School of Medicine, KY, USA
J Hand Surg Am 22:211-5. 1997
..A statistically significant association was found between obesity and median neuropathy. The implications of such a relationship are discussed in light of the contemporary debate over the etiology of cumulative trauma disorders...
- Simple screening tests for peripheral neuropathy in the diabetes clinic
B A Perkins
Beth Israel Deaconness Medical Center and Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 24:250-6. 2001
..The reported operating characteristics for each sensory modality can be applied to positive findings on the physical examination of individual patients to predict the likelihood of neuropathy...
- A neurophysiological grading scale for carpal tunnel syndrome
J D Bland
Kent and Canterbury Hospital, Canterbury, Kent, England
Muscle Nerve 23:1280-3. 2000
..5 ms; very severe (grade 5), terminal latency to APB > 6.5 ms; extremely severe (grade 6), sensory and motor potentials effectively unrecordable (surface motor potential from APB < 0.2 mV amplitude)...
- Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions
D G Flood
Department of Molecular Biology, Cephalon, Inc, West Chester, Pennsylvania, USA
Am J Pathol 155:663-72. 1999
..Therefore, Cu/Zn SOD is not required for normal motor neuron survival, but is necessary for the maintenance of normal neuromuscular junctions by hindlimb motor neurons...
- Hyper-responsivity in a subset of C-fiber nociceptors in a model of painful diabetic neuropathy in the rat
Departments of Anatomy, Medicine, and Oral and Maxillofacial Surgery, Division of Neuroscience, NIH Pain Center (UCSF, University of California, San Francisco 94143-0440, USA
Neuroscience 102:185-92. 2001
..The present findings suggest that study of individual neurons in vitro may allow elucidation of the ionic basis of enhanced nociception in diabetic neuropathy...
- Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications
Irina G Obrosova
Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
Diabetes 54:234-42. 2005
..These findings reveal the new beneficial properties of fidarestat, thus further justifying the ongoing clinical trials of this specific, potent, and low-toxic ARI...
- Detection of small-fiber neuropathy by sudomotor testing
Victoria A Low
Department of Neurology, Mayo Clinic, Guggenheim 811, 200 First Street SW, Rochester, Minnesota 55905, USA
Muscle Nerve 34:57-61. 2006
..Sudomotor examination is thus a highly sensitive detection tool in DSFN. Autonomic involvement is mainly distal, and additionally may involve adrenergic and the long cardiovagal fibers...
- Transplantation of olfactory ensheathing cells enhances peripheral nerve regeneration after microsurgical nerve repair
Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT 06510, USA
Brain Res 1254:10-7. 2009
..Even a modest improvement in nerve regeneration could have significant clinical implications for reconstructive nerve surgery...
- Direct measurement of somatic voltage clamp errors in central neurons
Stephen R Williams
Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
Nat Neurosci 11:790-8. 2008
..These errors question the use of the somatic voltage clamp as a quantitative tool in dendritic neurons...
- Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability
UNC Neuroscience Center, University of North Carolina at Chapel Hill 27599, USA
Cell 86:209-19. 1996
..These results indicate that GalC and sulfatide play important roles in myelin function and stability...
- The effects of normal aging on myelin and nerve fibers: a review
Department of Anatomy and Neurobiology, Boston University School of Medicine, 715, Albany Street, Boston, MA 02118, USA
J Neurocytol 31:581-93. 2002
..Degeneration of myelin itself does not seem to result in microglial cells undertaking phagocytosis. These cells are probably only activated when large numbers of nerve fibers are lost, as can occur in the optic nerve...
- The natural history of Charcot-Marie-Tooth type 1A in adults: a 5-year follow-up study
Department of Neurology and Clinical Neurophysiology, H2 222, Academic Medical Centre, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, The Netherlands
Brain 132:3252-62. 2009
..The slow increase in physical disability in adulthood may well be explained by decreased reserves and compensatory mechanisms together with progression of skeletal deformations due to muscle weakness...
- Diverse synaptic mechanisms generate direction selectivity in the rabbit retina
W Rowland Taylor
John Curtin School of Medical Research and Centre for Visual Sciences, Australian National University, Canberra, 2601 ACT, Australia
J Neurosci 22:7712-20. 2002
..The results indicate that, within a single neuron, different strategies are used within distinct dendritic arbors to accomplish the same neural computation...
- Multichannel surface EMG: basic aspects and clinical utility
Machiel J Zwarts
Department of Clinical Neurophysiology, Institute of Neurology, University Medical Center Nijmegen, PO Box 9101, NL 6500HB Nijmegen, The Netherlands
Muscle Nerve 28:1-17. 2003
..We conclude that multichannel sEMG adds unique, and sometimes indispensable, spatial information to our knowledge of the motor unit...
- Abeta-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals
Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom
Brain Res Brain Res Rev 46:131-45. 2004
..It is important that the existence of Abeta nociceptors is recognised, because assumptions that fast conducting, large diameter afferents are always low threshold mechanoreceptors might lead/have led to misinterpretations of data...
- Time-course changes in nerve conduction velocity (NCV) in type 2 diabetes
Saitama Social Insurance Hospital the Department of Internal Medicine, Saitama, Japan
J Diabetes Complications 26:237-40. 2012
..In addition, the natural course of diabetic sensorimotor polyneuropathy (DSPN) was discussed based on the findings...
- Progressive axonal dysfunction precedes development of neuropathy in type 2 diabetes
Jia Ying Sung
Department of Neurology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
Diabetes 61:1592-8. 2012
- Preparation and evaluation of NGF-microsphere conduits for regeneration of defective nerves
PLA General Hospital, Beijing, China
Neurol Res 34:491-7. 2012
..To fabricate nerve growth factor (NGF) microsphere conduits and evaluate their promotional effects on regeneration of defective nerves...
- The value added by electrodiagnostic testing in the diagnosis of carpal tunnel syndrome
Hand Program, Toronto Western Hospital, 399 Bathurst Street, East Wing 2 425, Toronto, ON M5T 2S8, Canada
J Bone Joint Surg Am 90:2587-93. 2008
- Distal degenerative sensory neuropathy in a long-term type 2 diabetes rat model
Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada
Diabetes 57:1664-73. 2008
..Peripheral neuropathy associated with type 2 diabetes (DPN) is not widely modeled. We describe unique features of DPN in type 2 diabetic Zucker diabetic fatty (ZDF) rats...
- Symptoms, signs and nerve conduction velocities in patients with suspected carpal tunnel syndrome
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton SO16 6YD, UK
BMC Musculoskelet Disord 14:242. 2013
- Differences in risk factors for neurophysiologically confirmed carpal tunnel syndrome and illness with similar symptoms but normal median nerve function: a case-control study
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton SO16 6YD, UK
BMC Musculoskelet Disord 14:240. 2013
- The dynamic clamp comes of age
Astrid A Prinz
Volen Center and Department of Biology, Brandeis University, Waltham, MA 02454 9110, USA
Trends Neurosci 27:218-24. 2004
- Dopamine modulation of Ih improves temporal fidelity of spike propagation in an unmyelinated axon
Aleksander W Ballo
The Whitney Laboratory for Marine Bioscience, University of Florida, St Augustine, Florida 32080, USA
J Neurosci 32:5106-19. 2012
..These results indicate that spike conduction can be extremely sensitive to the history of axonal activity and to the presence of neuromodulators, with potentially important consequences for temporal coding...
- Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial
Chubu Rosai Hospital, 1 10 6 Komei, Nagoya 455 8530, Japan
Diabetes Care 29:1538-44. 2006
..We sought to evaluate the long-term efficacy and safety of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy...
- Is surgical intervention more effective than non-surgical treatment for carpal tunnel syndrome? A systematic review
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, L8S 4L8, Canada
J Orthop Surg Res 6:17. 2011
..The purpose of this systematic review was to compare the efficacy of surgical treatment of carpal tunnel syndrome with conservative treatment...
- Effects of conduction delays on the existence and stability of one to one phase locking between two pulse-coupled oscillators
Michael Marmaduke Woodman
Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
J Comput Neurosci 31:401-18. 2011
..We successfully tested the predictions of our methods on networks of model neurons. The criteria can easily be extended to include the effect of an input on the cycle after the one in which it is received...
- Prediction of the neurophysiological diagnosis of carpal tunnel syndrome from the demographic and clinical data
Neurology Service, Hospital Sao Lucas da PUCRS, Porto Alegre, Brazil
Clin Neurophysiol 117:964-71. 2006
..To use demographic and clinical data to identify the clinical pattern that best predicts the diagnosis of carpal tunnel syndrome (CTS), as defined by neurophysiologic studies...
- Simulation in sensory neurons reveals a key role for delayed Na+ current in subthreshold oscillations and ectopic discharge: implications for neuropathic pain
Department of Cell and Developmental Biology, Institute of Life Sciences, Center for Research on Pain, Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel
J Neurophysiol 102:1430-42. 2009
..The model reveals the key conductances that underlie afferent ectopia, conductances that are potentially attractive targets in the search for more effective treatments of neuropathic pain...
- Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells
Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel
J Cell Biol 159:361-72. 2002
..The presence of these different tight junction proteins in regions of noncompact myelin may be required to maintain the intricate cytoarchitecture of myelinating Schwann cells...
- Inflammatory mediators enhance the excitability of chronically compressed dorsal root ganglion neurons
Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510, USA
J Neurophysiol 95:2098-107. 2006
..Inflammatory mediators, by increasing the excitability of DRG somata, may contribute to CCD-induced neuronal hyperexcitability and to hyperalgesia and tactile allodynia...
- Inactivation of sodium channels underlies reversible neuropathy during critical illness in rats
Kevin R Novak
Department of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, Ohio 45435, USA
J Clin Invest 119:1150-8. 2009
..Acquired sodium channelopathy may be the mechanism underlying acute neuropathy in critically ill patients...
- Effect of extracellular potassium accumulation on muscle fiber conduction velocity: a simulation study
School of Electrical, Electronic and Mechanical Engineering, University College Dublin, Dublin 4, Ireland
Ann Biomed Eng 37:2105-17. 2009
- A reassessment of stress-induced "analgesia" in the rat using an unbiased method
School of Medical Sciences, University of New South Wales, NSW 2052, Australia
Pain 152:676-86. 2011
..Less than two-thirds of the increase in tail-flick latency to noxious heat, evoked by conditioned fear, reflects true antinociception. The remaining is due to skin vasoconstriction...
- Nerve repair by end-to-side nerve coaptation: histologic and morphometric evaluation of axonal origin in a rat sciatic nerve model
Hannover Medical School, Institute of Neuroanatomy and Center for Systems Neuroscience, Hannover, Germany
Neurosurgery 66:567-76; discussion 576-7. 2010
..We compared the origin and quality of regenerating myelinated axons after end-to-side neurorrhaphy or end-to-end neurorrhaphy...
- Mutations in GDAP1: autosomal recessive CMT with demyelination and axonopathy
Molecular Genetics Department, Flanders Interuniversity Institute of Biotechnology, Belgium
Neurology 59:1865-72. 2002
- Muscle cramp in Machado-Joseph disease: altered motor axonal excitability properties and mexiletine treatment
Department of Neurology, Chiba University School of Medicine, Chiba, Japan
Brain 126:965-73. 2003
- Carpal tunnel syndrome with normal nerve conduction studies
John C Witt
Department of Neurology, Mayo Clinic, Scottsdale, Arizona, USA
Muscle Nerve 29:515-22. 2004
..We concluded that NCS provide independent information in the evaluation of suspected CTS, especially when fewer clinical criteria are present, but that NCS are not helpful in predicting the outcome of nonsurgical management...
- Ultrasonography versus nerve conduction study in patients with carpal tunnel syndrome: substantive or complementary tests?
Y M El Miedany
Darent Valley Hospital, Dartford, Kent DA2 8DA, UK
Rheumatology (Oxford) 43:887-95. 2004
- The value of the history in the diagnosis of carpal tunnel syndrome
J D Bland
EEG Department, Kent and Canterbury Hospital, Kent, UK
J Hand Surg Br 25:445-50. 2000
..A simple regression model for evaluating the history compares favourably with widely used clinical signs in its ability to predict the findings of nerve conduction studies...
- Small fibre impairment predicts neuropathic pain in Guillain-Barré syndrome
Université de Versailles St Quentin, AP HP, Hopital Raymond Poincare, Service d Anesthésie Réanimation Chirurgicale, 104 boulevard Raymond Poincaré, 92380 Garches, France
Pain 151:53-60. 2010
..These findings emphasize the importance of nociceptive fibre impairment in NP in GBS at both acute and chronic stages and suggest similarities between the mechanisms of NP in GBS and those of small fibre painful sensory polyneuropathies...
- Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy
University of Calgary, Department of Clinical Neurosciences, Room 155, 3330 Hospital Dr, N W, Calgary, Alberta T2N 4N1, Canada
Diabetes 57:1002-17. 2008
..We studied experimental diabetic neuropathy and its relationship with RAGE expression using streptozotocin-induced diabetic mice including a RAGE(-/-) cohort exposed to long-term diabetes compared with littermates without diabetes...
- Conduction velocity is regulated by sodium channel inactivation in unmyelinated axons innervating the rat cranial meninges
Roberto De Col
Institute for Physiology and Pathophysiology, University of Erlangen Nuremberg, Erlangen, Germany
J Physiol 586:1089-103. 2008
..Since the process is primarily dependent upon sodium channel availability, tracking conduction velocity provides a means of accessing relative changes in the excitability of nociceptive neurons...
- Allopregnanolone prevents and suppresses oxaliplatin-evoked painful neuropathy: multi-parametric assessment and direct evidence
Universite de Strasbourg, Bâtiment 3 de la Faculté de Médecine, Strasbourg, France
Pain 152:170-81. 2011
..Together, these results may be interesting for the development of natural or safe neurosteroid-based neuroprotective strategy against anticancer drug-evoked painful neuropathy...
- Neurofascins are required to establish axonal domains for saltatory conduction
Diane L Sherman
Centre for Neuroscience Research, University of Edinburgh, Edinburgh EH9 1QH, United Kingdom
Neuron 48:737-42. 2005
- C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Diabetes Care 30:71-6. 2007
..The present study was undertaken to examine whether C-peptide administration to patients with type 1 diabetes and peripheral neuropathy improves sensory nerve function...
- Activity-dependent excitability changes suggest Na+/K+ pump dysfunction in diabetic neuropathy
Arun V Krishnan
Prince of Wales Medical Research Institute, Prince of Wales Clinical School, University of New South Wales, Randwick, Sydney, NSW, Australia
Brain 131:1209-16. 2008
..Alteration in Na(+)/K(+) pump function, coupled with reductions in nodal Na(+) currents, may be sufficient to trigger conduction failure in DN patients and are likely to contribute to the clinical symptoms of weakness and fatigue...
- Relationship between the self-administered Boston questionnaire and electrophysiological findings in follow-up of surgically-treated carpal tunnel syndrome
Unit of Neurosurgery, Azienda Ospedialiera Senese and Department of Neurology, Catholic University, Rome, Italy
J Hand Surg Br 25:128-34. 2000
- Exploring a critical parameter of timing in the mouse cerebellar microcircuitry: the parallel fiber diameter
Sektion fur Visuelle Sensomotorik, Neurologische Universitätsklinik Tübingen, Germany
Neurosci Lett 280:41-4. 2000
- Electrical synapses and synchrony: the role of intrinsic currents
Laboratoire de Neurophysique et Physiologie du Système Moteur, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8119, Universite Rene Descartes, 75270 Paris Cedex 06, France
J Neurosci 23:6280-94. 2003
..It also suggests different synchronization properties for LTS and FS cells. Finally, we propose to further test our predictions in experiments using dynamic clamp techniques...
- Diagnostic utility of ultrasonography versus nerve conduction studies in mild carpal tunnel syndrome
EMG Service ASL 7, Siena, Italy
Arthritis Rheum 59:357-66. 2008
..To prospectively compare high-resolution ultrasonography (US) and nerve conduction velocity (NCV) in clinically diagnosed mild carpal tunnel syndrome (CTS)...
- Axonal neuregulin-1 regulates myelin sheath thickness
Galin V Michailov
Department of Neurogenetics, Max Planck Institute of Experimental Medicine, 37075 Gottingen, Germany
Science 304:700-3. 2004
..We suggest a model by which myelin-forming Schwann cells integrate axonal Nrg1 signals as a biochemical measure of axon size...
- Osteoarthritis: symptoms, signs and source of pain
W F Kean
Hamilton Health Sciences, McMaster University, Ontario, Canada
Inflammopharmacology 12:3-31. 2004
..This lack of correlation of clinical evaluation and imaging makes attempts at treatment difficult and compromises attempts to design studies and to evaluate the outcome of osteoarthritis in clinical trials...
- Conduction velocity of nerve and muscle fiber action potentials after a space mission or a bed rest
Dieter G Ruegg
Institute of Physiology, University of Fribourg, Rue du Musee 5, CH 1700, Fribourg, Switzerland
Clin Neurophysiol 114:86-93. 2003
..The purpose of the present investigation was to study the readaptation of a human muscle after a prolonged stay in microgravity and after a bed rest of several months...
- Caveolin-1 and altered neuregulin signaling contribute to the pathophysiological progression of diabetic peripheral neuropathy
James F McGuire
Department of Pharmacology and Toxicology, University of Kansas, Lawrence, Kansas, USA
Diabetes 58:2677-86. 2009
..Evaluate if Erb B2 activation and the loss of caveolin-1 (Cav1) contribute to the pathophysiological progression of diabetic peripheral neuropathy (DPN)...
- Carpal tunnel syndrome: diagnostic usefulness of sonography
Shiu Man Wong
Department of Medicine, Prince of Wales Hospital, Shatin, Hong Kong
Radiology 232:93-9. 2004
..To prospectively evaluate accuracy of sonography for diagnosis of carpal tunnel syndrome (CTS) in patients clinically suspected of having the disease in one or both hands...
- The acute effects of glycemic control on axonal excitability in human diabetic nerves
Department of Neurology, Chiba University School of Medicine
Intern Med 41:360-5. 2002
..It is known that voluntary contraction or compression ischemia alters nerve Na+/K+ pump activity, and axonal excitability changes due to the pump activity can be estimated by threshold tracking...
- Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy
M J Stevens
Division of Endocrinology and Metabolism, University of Michigan, Ann Arbor 48109 0678, USA
Diabetes 49:1006-15. 2000
..They reveal complex interrelationships among nerve perfusion, energy metabolism, osmolyte content, conduction velocity, and oxidative stress that may reflect the heterogeneous and compartmentalized composition of peripheral nerve...
- Effect of treating streptozotocin-induced diabetic rats with sorbinil, myo-inositol or aminoguanidine on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve
Lawrence J Coppey
Veterans Affairs Medical Center, Department of Internal Medicine, University of Iowa, Iowa City 52246, USA
Int J Exp Diabetes Res 3:21-36. 2002
..These studies suggest that sorbinil treatment may be more effective in preventing neural dysfunction in diabetes than either aminoguanidine or myo-inositol...
- Severity of Carpal tunnel syndrome assessed with high frequency ultrasonography
Yeşim Sücüllü Karadağ
1st Neurology Clinic, Ankara Numune Education and Research Hospital, Ankara, Turkey
Rheumatol Int 30:761-5. 2010
..In addition to CTS diagnosis, sonographic measurement of CSA could also give additional information about severity of median nerve involvement. Using of US may cost-effectively reduce the number of NCS in patients with suspected CTS...
- Effect of aging on sensory nerve conduction study parameters
Henry C Tong
Department of Physical Medicine and Rehabilitation, School of Medicine, University of Michigan, Ann Arbor, Michigan, USA
Muscle Nerve 29:716-20. 2004
..The rate of change seen with some of the median nerve parameters was significantly greater than that with the ulnar nerve...
- Action potentials contribute to neuronal signaling in C. elegans
Jerry E Mellem
Department of Biology, University of Utah, Salt Lake City, Utah 84112 0840, USA
Nat Neurosci 11:865-7. 2008
..These neurons resembled Schmitt triggers, as their potential state appears to be bistable. Transitions between up and down states could be triggered by application of the neurotransmitter glutamate or brief current pulses...
- Multifocal motor neuropathy: pathologic alterations at the site of conduction block
Bruce V Taylor
Department of Neurology, Royal Hobart Hospital, Hobart Tasmania, Australia
J Neuropathol Exp Neurol 63:129-37. 2004
- Follow-up study and response to treatment in 23 patients with Lewis-Sumner syndrome
Fédération de Neurophysiologie Clinique, Hopital de la Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
Brain 127:2010-7. 2004
..Overall, whatever the clinical course, LSS responded to immune-mediated treatment in a manner similar to CIDP...
- Neuropathy progression in Charcot-Marie-Tooth disease type 1A
M E Shy
Wayne State University, Department of Neurology, Center for Molecular Medicine and Genetics, 421 Ea Canfield, Detroit, MI 48201, USA
Neurology 70:378-83. 2008
..To determine the rate of disease progression in Charcot-Marie-Tooth disease type 1A (CMT1A)...
- Space-clamp problems when voltage clamping neurons expressing voltage-gated conductances
Mina and Everard Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
J Neurophysiol 99:1127-36. 2008
..Our results demonstrate that voltage-gated K(+) and Ca(2+) currents recorded from branching neurons are almost always severely distorted...
- A clinical, electrophysiological, and pathological study of neuropathy in rheumatoid arthritis
Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India
Clin Rheumatol 27:841-4. 2008
..Pathologically, neuropathy secondary to amyloid infiltration was second only to vasculitic neuropathy. Absence of deep tendon jerks and presence of vasculitis were more commonly observed in patients with neuropathy...
- A new method for the estimation of motor nerve conduction block
LISiN, Dipartimento di Elettronica, Politecnico di Torino, Corso Duca degli Abruzzi 24, Turin 10129, Italy
Clin Neurophysiol 118:730-40. 2007
- Impaired neural conduction in crossed visual pathways in patients with ocular hypertension
Ophthalmology Department, University of Roma Tor Vergata, Roma Italy
Eur J Ophthalmol 14:486-94. 2004
To evaluate the neural conduction along crossed and uncrossed visual pathways in patients with ocular hypertension (OHT).