anaerobic threshold

Summary

Summary: The oxygen consumption level above which aerobic energy production is supplemented by anaerobic mechanisms during exercise, resulting in a sustained increase in lactate concentration and metabolic acidosis. The anaerobic threshold is affected by factors that modify oxygen delivery to the tissues; it is low in patients with heart disease. Methods of measurement include direct measure of lactate concentration, direct measurement of bicarbonate concentration, and gas exchange measurements.

Top Publications

  1. ncbi Anaerobic threshold: the concept and methods of measurement
    Krista Svedahl
    Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, 2500 University Dr NW, Calgary, AB, T2N 1N4
    Can J Appl Physiol 28:299-323. 2003
  2. ncbi Cardiopulmonary exercise testing as a screening test for perioperative management of major surgery in the elderly
    P Older
    Western Hospital, Footscray, Victoria, Australia
    Chest 116:355-62. 1999
  3. ncbi Effect of endurance training program based on anaerobic threshold (AT) for lower limb amputees
    T Chin
    Hyogo Rehabilitation Center, Kobe, Japan
    J Rehabil Res Dev 38:7-11. 2001
  4. ncbi Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early death
    Anselm K Gitt
    Herzzentrum Ludwigshafen, Department of Cardiology, Ludwigshafen, Germany
    Circulation 106:3079-84. 2002
  5. ncbi Controversies in the physiological basis of the 'anaerobic threshold' and their implications for clinical cardiopulmonary exercise testing
    J G Hopker
    Centre for Sports Studies, University of Kent, Chatham Maritime, Chatham, Kent, UK
    Anaesthesia 66:111-23. 2011
  6. ncbi Inverse relationship between VO2max and economy/efficiency in world-class cyclists
    Alejandro Lucia
    Departamento de Ciencias Morfológicas y Fisiología, Universidad Europea de Madrid, E 28670 Villaviciosa de Odón, Madrid, Spain
    Med Sci Sports Exerc 34:2079-84. 2002
  7. ncbi Step length and individual anaerobic threshold assessment in swimming
    R J Fernandes
    Faculty of Sport, CIFI2D, University of Porto, Portugal
    Int J Sports Med 32:940-6. 2011
  8. ncbi Determination of the anaerobic threshold and maximal lactate steady state speed in equines using the lactate minimum speed protocol
    Fernando José Gondim
    Laboratório de Imunopatologia Experimental, Universidade Federal de Goias, Goiania, Brasil
    Comp Biochem Physiol A Mol Integr Physiol 146:375-80. 2007
  9. ncbi Pain threshold is achieved at intensity above anaerobic threshold in patients with intermittent claudication
    Raphael Mendes Ritti-Dias
    Department of Nutrition, School of Public Health, Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
    J Cardiopulm Rehabil Prev 29:396-401. 2009
  10. ncbi Comparison of anaerobic threshold determined by visual and mathematical methods in healthy women
    M N Higa
    Departamento de Ginecologia e Obstetricia, Hospital das Clinicas, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Brasil
    Braz J Med Biol Res 40:501-8. 2007

Detail Information

Publications191 found, 100 shown here

  1. ncbi Anaerobic threshold: the concept and methods of measurement
    Krista Svedahl
    Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, 2500 University Dr NW, Calgary, AB, T2N 1N4
    Can J Appl Physiol 28:299-323. 2003
    The anaerobic threshold (AnT) is defined as the highest sustained intensity of exercise for which measurement of oxygen uptake can account for the entire energy requirement...
  2. ncbi Cardiopulmonary exercise testing as a screening test for perioperative management of major surgery in the elderly
    P Older
    Western Hospital, Footscray, Victoria, Australia
    Chest 116:355-62. 1999
    ..To develop an integrated strategy for the identification and subsequent management of high-risk patients in order to reduce both morbidity and mortality...
  3. ncbi Effect of endurance training program based on anaerobic threshold (AT) for lower limb amputees
    T Chin
    Hyogo Rehabilitation Center, Kobe, Japan
    J Rehabil Res Dev 38:7-11. 2001
    ..cycling test driven by the subject's sound leg as the exercise load test is effective in measuring the anaerobic threshold (AT) of unilateral lower limb amputees...
  4. ncbi Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early death
    Anselm K Gitt
    Herzzentrum Ludwigshafen, Department of Cardiology, Ludwigshafen, Germany
    Circulation 106:3079-84. 2002
    ..In contrast, the anaerobic threshold (VO2AT) and the ventilatory efficiency (VE versus VCO2 slope) are less subject to these influences...
  5. ncbi Controversies in the physiological basis of the 'anaerobic threshold' and their implications for clinical cardiopulmonary exercise testing
    J G Hopker
    Centre for Sports Studies, University of Kent, Chatham Maritime, Chatham, Kent, UK
    Anaesthesia 66:111-23. 2011
    This article reviews the notion of the 'anaerobic threshold' in the context of cardiopulmonary exercise testing...
  6. ncbi Inverse relationship between VO2max and economy/efficiency in world-class cyclists
    Alejandro Lucia
    Departamento de Ciencias Morfológicas y Fisiología, Universidad Europea de Madrid, E 28670 Villaviciosa de Odón, Madrid, Spain
    Med Sci Sports Exerc 34:2079-84. 2002
    ..Cycling economy (CE) and gross mechanical efficiency (GE) were calculated during the constant-load tests...
  7. ncbi Step length and individual anaerobic threshold assessment in swimming
    R J Fernandes
    Faculty of Sport, CIFI2D, University of Porto, Portugal
    Int J Sports Med 32:940-6. 2011
    b>Anaerobic threshold is widely used for diagnosis of swimming aerobic endurance but the precise incremental protocols step duration for its assessment is controversial...
  8. ncbi Determination of the anaerobic threshold and maximal lactate steady state speed in equines using the lactate minimum speed protocol
    Fernando José Gondim
    Laboratório de Imunopatologia Experimental, Universidade Federal de Goias, Goiania, Brasil
    Comp Biochem Physiol A Mol Integr Physiol 146:375-80. 2007
    Maximal blood lactate steady state concentration (MLSS) and anaerobic threshold (AT) have been shown to accurately predict long distance events performance and training loads, as well, in human athletes...
  9. ncbi Pain threshold is achieved at intensity above anaerobic threshold in patients with intermittent claudication
    Raphael Mendes Ritti-Dias
    Department of Nutrition, School of Public Health, Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
    J Cardiopulm Rehabil Prev 29:396-401. 2009
    ..However, the relationship between these methods and anaerobic threshold (AT), which is considered one of the best metabolic markers for establishing training intensity, has not ..
  10. ncbi Comparison of anaerobic threshold determined by visual and mathematical methods in healthy women
    M N Higa
    Departamento de Ginecologia e Obstetricia, Hospital das Clinicas, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Brasil
    Braz J Med Biol Res 40:501-8. 2007
    Several methods are used to estimate anaerobic threshold (AT) during exercise...
  11. ncbi Plasma adiponectin response to sculling exercise at individual anaerobic threshold in college level male rowers
    J Jurimae
    Institute of Sport Pedagogy and Coaching Sciences, Centre of Behavioural and Health Sciences, University of Tartu, Tartu, Estonia
    Int J Sports Med 27:272-7. 2006
    ..5 km (approximately 30 min) at the individual anaerobic threshold (75.2+/-2.9% of VO2max). Adiponectin was unchanged (p>0.05) immediately after the exercise...
  12. ncbi Total protein of whole saliva as a biomarker of anaerobic threshold
    Miguel Junior Sordi Bortolini
    Laboratory of Biomechanics and Molecular Biology, Federal University of Uberlandia, Brazil
    Res Q Exerc Sport 80:604-10. 2009
    ..We investigated whether the total protein concentration of whole saliva (TPWS) would reflect the anaerobic threshold during an incremental exercise test...
  13. ncbi [Methods to identify the anaerobic threshold for type-2 diabetic and non-diabetic subjects]
    Herbert G Simões
    Universidade Catolica de Brasilia, Brasilia, DF, Brasil
    Arq Bras Cardiol 94:71-8. 2010
    In spite of Anaerobic Threshold (AT) to be widely used on exercise evaluation for different populations, there are few studies comparing methods to identify AT for individuals with type-2 diabetes.
  14. ncbi Venous saturation and the anaerobic threshold in neonates after the Norwood procedure for hypoplastic left heart syndrome
    G M Hoffman
    Department of Anesthesiology, Children s Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee 53226, USA
    Ann Thorac Surg 70:1515-20; discussion 1521. 2000
    ..detectable by progressive (mixed) venous oxyhemoglobin desaturation until extraction is limited at the anaerobic threshold. We sought to determine the critical level of venous oxygen saturation to maintain aerobic metabolism in ..
  15. ncbi Effect of the aerobic capacity on the validity of the anaerobic threshold for determination of the maximal lactate steady state in cycling
    B S Denadai
    Laboratório da Avaliação da Performance Humana, Instituto de Biociencias, Universidade Estadual Paulista, 13506 900 Rio Claro, Sao Paulo, Brazil
    Braz J Med Biol Res 37:1551-6. 2004
    ..The objective of the present study was to analyze the influence of the aerobic capacity on the validity of anaerobic threshold (AT) to estimate the exercise intensity at MLSS (MLSS intensity) during cycling...
  16. ncbi The ventilatory anaerobic threshold in heart failure: a multicenter evaluation of reliability
    Jonathan Myers
    VA Palo Alto Health Care System Stanford University, Palo Alto CA 94304, USA
    J Card Fail 16:76-83. 2010
    ..We quantified the reliability of VT determination using data from a multicenter study in patients with heart failure...
  17. ncbi Acute exercise performed close to the anaerobic threshold improves cognitive performance in elderly females
    C Cordova
    Programa de Pós Graduação stricto sensu em Educação Física e Saúde, Laboratório de Estudos em Educação Física e Saúde, Universidade Catolica de Brasilia, Brasilia, DF, Brasil
    Braz J Med Biol Res 42:458-64. 2009
    ..study was to compare the effect of acute exercise performed at different intensities in relation to the anaerobic threshold (AT) on abilities requiring control of executive functions or alertness in physically active elderly ..
  18. ncbi Anaerobic threshold and random venous lactate levels among HIV-positive patients on antiretroviral therapy
    Alicja M Tesiorowski
    J Acquir Immune Defic Syndr 31:250-1. 2002
  19. ncbi Determination of anaerobic threshold in rats using the lactate minimum test
    F A Voltarelli
    Departamento de Educacao Fisica, Instituto de Biologia, Universidade Estadual Paulista, Rio Claro, SP, Brasil
    Braz J Med Biol Res 35:1389-94. 2002
    The break point of the curve of blood lactate vs exercise load has been called anaerobic threshold (AT) and is considered to be an important indicator of endurance exercise capacity in human subjects...
  20. ncbi Comparison of W(peak), VO2(peak) and the ventilation threshold from two different incremental exercise tests: relationship to endurance performance
    D J Bentley
    Department of Human and Health Science, University of Westminster, United Kingdom
    J Sci Med Sport 6:422-35. 2003
    ..Furthermore, the W(peak) obtained from a test incorporating 3 min stage increments represents the best indicator of 90 min cycle performance in well-trained triathletes...
  21. ncbi Aerobic fitness effects in fibromyalgia
    Valeria Valim
    Department of Medicine, Sao Paulo Federal University, Sao Paulo, Brazil
    J Rheumatol 30:1060-9. 2003
    ....
  22. ncbi Peak oxygen uptake and ventilatory anaerobic threshold in fibromyalgia
    Valeria Valim
    Department of Medicine and Sports and Physic al Medical Center, Sao Paulo Federal University, Sao Paulo, Brazil
    J Rheumatol 29:353-7. 2002
    To compare maximum oxygen uptake and anaerobic threshold in patients with fibromyalgia (FM) and healthy sedentary controls matched by sex, age, weight, and body mass index.
  23. ncbi The body weight-walking distance product as related to lung function, anaerobic threshold and peak VO2 in COPD patients
    M L Chuang
    Division of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC
    Respir Med 95:618-26. 2001
    ..hypothesized the superiority of D x W to walking distance (D) alone in any correlation with lung function, anaerobic threshold (AT) and maximal oxygen uptake (VO2max)...
  24. ncbi A randomized controlled trial of deep water running: clinical effectiveness of aquatic exercise to treat fibromyalgia
    Marcos Renato Assis
    Division of Rheumatology, Sao Paulo Federal University, Rua Botucatu 740, 04023 900 São Paulo, Brazil
    Arthritis Rheum 55:57-65. 2006
    ..To compare the clinical effectiveness of aerobic exercise in the water with walking/jogging for women with fibromyalgia (FM)...
  25. ncbi Lactate threshold concepts: how valid are they?
    Oliver Faude
    Institute of Sports Medicine, University Paderborn, Paderborn, Germany
    Sports Med 39:469-90. 2009
    ..The presented framework may help to clarify some aspects of the controversy and may give a rationale for performance diagnosis and training prescription in future research as well as in sports practice...
  26. ncbi Blood coagulation and fibrinolysis after long-duration treadmill exercise controlled by individual anaerobic threshold
    Thomas Hilberg
    Department of Sports Medicine, Friedrich Schiller University Jena, Wöllnitzerstrasse 42, 07749, Jena, Germany
    Eur J Appl Physiol 90:639-42. 2003
    ..training it is recommended that the intensity of exercise should be clearly below the individual anaerobic threshold (IAT)...
  27. ncbi Pattern of energy expenditure during simulated competition
    Carl Foster
    Department of Exercise and Sport Science, University of Wisconsin La Crosse, La Crosse, WI 54601, USA
    Med Sci Sports Exerc 35:826-31. 2003
    ..To determine how athletes spontaneously use their energetic reserves when the only instruction was to finish in minimal time, and whether experience from repeated performance changes the strategy of recreational athletes...
  28. ncbi Cardiovascular testing in Fabry disease: exercise capacity reduction, chronotropic incompetence and improved anaerobic threshold after enzyme replacement
    T Lobo
    Department of Nephrology, Royal Melbourne Hospital, Melbourne, Victoria, Australia
    Intern Med J 38:407-14. 2008
    ..The aim of this study was to document exercise capacity and serial electrocardiogram and echocardiograph findings in a cohort of Australian patients with Fabry disease, in relation to their history of enzyme replacement therapy (ERT)...
  29. ncbi Comparison of pulmonary gas exchange measurements between incremental and constant work exercise above the anaerobic threshold
    R J Zeballos
    Department of Clinical Investigation, William Beaumont Army Medical Center, El Paso 79920 5001, USA
    Chest 113:602-11. 1998
    ....
  30. ncbi Assessment of the chronotropic response at the anaerobic threshold: an objective measure of chronotropic function
    M Meine
    Department of Cardiology and Angiology, Marienhospital, Herne, Germany
    Pacing Clin Electrophysiol 23:1457-67. 2000
    ..The heart rate at the anaerobic threshold was significantly lower in the chronotropically incompetent subgroup than in the chronotropically competent ..
  31. ncbi Exercise efficiency of girls with idiopathic scoliosis based on the ventilatory anaerobic threshold
    Jacek Durmala
    Department of Rehabilitation, Medical University of Silesiaa, Katowice, Poland 40 635 Katowice, Ul Ziolowa 45 47 POLAND
    Stud Health Technol Inform 91:357-60. 2002
    The aim of the study was to estimate the exercise efficiency in the group of girls with idiopathic scoliosis based on the ventilatory anaerobic threshold (VAT).
  32. ncbi L -Carnitine and the recovery from exhaustive endurance exercise: a randomised, double-blind, placebo-controlled trial
    Christoph Stuessi
    Exercise Physiology, Institute of Human Movement Sciences, Swiss Federal Institute of Technology of Zurich, Zurich, Switzerland
    Eur J Appl Physiol 95:431-5. 2005
    ..administration, the subjects performed a constant-load exercise test (CET(1)) cycling at their individual anaerobic threshold to exhaustion. Three hours later this test was repeated (CET(2))...
  33. ncbi [Effects of swimming with a wet suit on energy expenditure during subsequent cycling]
    Anne Delextrat
    Laboratoire Ergonomie Sportive et Performance, EA 3162, Université de ToulonVar, Avenue de l Universite, BP 132, 83957 LaGarde, France
    Can J Appl Physiol 28:356-69. 2003
    ..1% difference, p < 0.05). The lower relative intensity observed during swimming with a wetsuit suggest the relative importance of swimming condition on the total performance in a sprint triathlon...
  34. ncbi The effects of creatine supplementation on performance during the repeated bouts of supramaximal exercise
    N Okudan
    Department of Physiology, Meram Faculty of Medicine, Selcuk University, Konya, Turkey
    J Sports Med Phys Fitness 45:507-11. 2005
    ..The aim of this study was to investigate the effects of creatine supplementation on performance during the repeated bouts of supramaximal exercise...
  35. ncbi Facial cooling-induced bradycardia does not slow pulmonary V.O2 kinetics at the onset of high-intensity exercise
    Masako Endo
    Dept of Exercise Science and Physiology, School of Health Sciences, Hiroshima Prefectural Women s Univ, 1 1 71, Ujina higashi, Minamiku, Hiroshima 734 8558, Japan
    J Appl Physiol 95:1623-31. 2003
    ..As the facilitation of Vo2 subsequent to prior heavy leg cycling exercise is not attenuated by slowing the central circulation, it seems unlikely that this facilitation is exclusively determined by a blood flow-related mechanism...
  36. ncbi RPE-lactate dissociation during extended cycling
    J M Green
    Department of Kinesiology, University of Alabama, Tuscaloosa, 35487 0312, USA
    Eur J Appl Physiol 94:145-50. 2005
    ..06) were weak and non-significant. There is a dissociation of RPE and [LA] owing to RPE drift and lactate kinetics in longer duration sub-maximal exercise. Apparently, [LA] is not a strong RPE mediator during extended cycling...
  37. ncbi Assessment of maximal aerobic velocity in soccer players by means of an adapted Probst field test
    Z Labsy
    Research Centre of Sport Science, UFR STAPS d Orsay, Orsay, France
    J Sports Med Phys Fitness 44:375-82. 2004
    ..4 km x h(-1) and a 0.6 km x h(-1) increment at each stage. The adapted version was carried out with the same protocol but constant stages of 2-minute durations and a 1.2 km x h(-1) increment at each stage...
  38. ncbi No effect of menstrual cycle phase on lactate threshold
    Teresa M Dean
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Appl Physiol 95:2537-43. 2003
    ..Data suggest that the onset of the steep increase in epinephrine determines the LT during graded exercise...
  39. ncbi Physiological responses using 2 high-speed resistance training protocols
    Carla Werlang Coelho
    Physical Education Graduate Program, Gama Filho University, Rio de Janeiro, Brazil
    J Strength Cond Res 17:334-7. 2003
    ..These findings may help foster long-term adherence to RT in untrained individuals. However, future studies are needed to compare physiological adaptations induced by these 2 RT protocols...
  40. ncbi Oxygen uptake kinetics during supra VO2max treadmill running in humans
    H Carter
    Chelsea School Research Centre, University of Brighton, Eastbourne, UK
    Int J Sports Med 27:149-57. 2006
    ..This suggests the need for a reappraisal of the VO2/work rate relationship in running exercise...
  41. pmc Endurance training and testing with the ball in young elite soccer players
    K Chamari
    Unité de Recherche Evaluation, Sport, santé, National Centre of Medicine and Sciences in Sport CNMSS, El Menzah, Tunisia
    Br J Sports Med 39:24-8. 2005
    ..We further determined whether improvement in maximal oxygen uptake was reflected in increased distance covered in the Hoff test...
  42. ncbi Exercise with the intensity of the individual anaerobic threshold in acute hypoxia
    Birgit Friedmann
    Department of Sports Medicine, Medical Clinic and Policlinic, University of Heidelberg, Germany
    Med Sci Sports Exerc 36:1737-42. 2004
    The aim of the present study was to find out if the determination of the individual anaerobic threshold (IAT) during incremental treadmill tests in normoxia and acute normobaric hypoxia (FiO2 0...
  43. pmc Assessment of ventilatory thresholds during graded and maximal exercise test using time varying analysis of respiratory sinus arrhythmia
    G Blain
    Département Ergonomie Sportive et Performances, Universite de Toulon Var, Nice, France
    Br J Sports Med 39:448-52; discussion 448-52. 2005
    ..To test whether ventilatory thresholds, measured during an exercise test, could be assessed using time varying analysis of respiratory sinus arrhythmia frequency (f(RSA))...
  44. ncbi Individual variation in the reduction of heart rate and performance at lactate thresholds in acute normobaric hypoxia
    B Friedmann
    Department of Sports Medicine, Medical Clinic and Policlinic, University of Heidelberg, Heidelberg, Germany
    Int J Sports Med 26:531-6. 2005
    ..In conclusion, heart rate and performance have to be reduced individually to a varying extent during exercise in a hypoxic environment in order to achieve an equivalent intensity compared to exercise in normoxia...
  45. ncbi A comparison of methods for estimating the lactate threshold
    James C McGehee
    Department of Exercise and Sport Science, East Carolina University, Greenville, NC 27858, USA
    J Strength Cond Res 19:553-8. 2005
    ..These findings suggest that the 30-minute time-trial method should be considered by coaches and distance runners/triathletes as a method for estimating both the running velocity and heart rate at the lactate threshold...
  46. ncbi Effects of human pregnancy and aerobic conditioning on alveolar gas exchange during exercise
    Sonja E McAuley
    School of Physical and Health Education, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Can J Physiol Pharmacol 83:625-33. 2005
    ..Training-induced increases in T(vent) and peak oxygen pulse support the efficacy of prenatal fitness programs to improve maternal work capacity...
  47. ncbi Effect of a 15% increase in preferred pedal rate on time to exhaustion during heavy exercise
    Xavier Nesi
    Faculte des Sciences du Sport et de l Education Physique, Universite de Lille, France
    Can J Appl Physiol 29:146-56. 2004
    ....
  48. ncbi Physiological and biomechanical responses while running with and without a stroller
    J D Smith
    Department of Health and Physical Education, Texas A and M University, Kingsville, TX, USA
    J Sports Med Phys Fitness 45:270-6. 2005
    ..The hypothesis was that running with a stroller for 30 minutes would shorten stride length and increase physiological indices of exercise...
  49. ncbi Leg tourniquets modify the on-kinetics of oxygen uptake during cycle exercise
    Douglas R Knight
    College of Medicine and Public Health, The Ohio State University, Columbus, USA
    J Cardiopulm Rehabil 24:128-35. 2004
    ..This study sought to determine whether obstructed blood flow decelerates the on-kinetics of VO2 by reducing O2 delivery...
  50. ncbi Effects of body mass index on maximal work production capacity and aerobic fitness during incremental exercise
    O Ozcelik
    Department of Physiology, Faculty of Medicine TIP, Firat University 23119, Elazig Turkey
    Physiol Res 53:165-70. 2004
    ....
  51. ncbi Relationships and significance of lactate minimum, critical velocity, heart rate deflection and 3 000 m track-tests for running
    H G Simoes
    Catholic University of Brasilia, Brasilia DF, Brazil
    J Sports Med Phys Fitness 45:441-51. 2005
    ..000 m (V(3000)) and 10 000 m performance (V10km) were compared. Additionally the ability of V(lm) and V(HRd) on identifying sustainable velocities was investigated...
  52. ncbi Circadian rhythms in blood lactate concentration during incremental ergometer rowing
    J J Forsyth
    Sport and Exercise Sciences, North East Wales Institute of Higher Education, Plas Coch, Mold Road, Wrexham, Wales, LL20 7UR, UK
    Eur J Appl Physiol 92:69-74. 2004
    ..The conclusion is that tests should be completed at the same time of day at which the athlete usually trains, to ensure precision of Th(lac) determination, especially when the D(max )method is used to determine Th(lac)...
  53. ncbi Residual effects of prior exercise and recovery on subsequent exercise-induced metabolic responses
    Ola Ronsen
    Norwegian Olympic Sports Center, Ullevaal Stadion, Box 4004, 0806 Oslo, Norway
    Eur J Appl Physiol 92:498-507. 2004
    ..Thus, augmented metabolic stress was observed when strenuous exercise was repeated after only 3 h of recovery, but this was attenuated when a longer recovery period including an additional meal was provided between the exercise sessions...
  54. ncbi Injections of recombinant human erythropoietin increases lactate influx into erythrocytes
    Philippe Connes
    Faculte des Sciences du Sport et de l Education Physique, F 34090 Montpellier, France
    J Appl Physiol 97:326-32. 2004
    ..The increase in MCT-1 maximal velocity suggests that rHuEPO may stimulate MCT-1 synthesis during erythrocyte formation in bone marrow...
  55. ncbi Endurance training improves skeletal muscle electrical activity in active COPD patients
    Nadège Gosselin
    Sport, Performance, Health Laboratory, Faculty of Sport Sciences, 700 Av du Pic St Loup, 34090 Montpellier, France
    Muscle Nerve 28:744-53. 2003
    ..Pulmonary rehabilitation in active COPD patients may normalize the electrical activity of skeletal muscles during incremental dynamic exercise. The electromyographic signal confirms neuromuscular changes after endurance training...
  56. ncbi Blood lactate removal during recovery at various intensities below the individual anaerobic threshold in triathletes
    C Baldari
    University Institute of Motor Sciences IUSM, Rome, Italy
    J Sports Med Phys Fitness 45:460-6. 2005
    ..not in percentage of VO2max but in relation to validated metabolic reference points such as the individual anaerobic threshold (IAT) and the individual ventilatory threshold (IVT)...
  57. ncbi Oxygen uptake kinetics during moderate, heavy and severe intensity "submaximal" exercise in humans: the influence of muscle fibre type and capillarisation
    Jamie S M Pringle
    Department of Exercise and Sport Science, Manchester Metropolitan University, Hassall Road, Alsager ST7 2HL, UK
    Eur J Appl Physiol 89:289-300. 2003
    ..VO(2) response at the onset of constant-load sub-maximal exercise. Differences in contraction efficiency and oxidative enzyme activity between type I and type II muscle fibres may be responsible for the differences observed...
  58. ncbi Maximal lactate steady state, respiratory compensation threshold and critical power
    J Dekerle
    Laboratoire d Etudes de la Motricite Humaine, Faculté des Sciences du Sport et de l EP, Lille 2, 9 Rue de l Université, 59790 Ronchin, France
    Eur J Appl Physiol 89:281-8. 2003
    ..93, respectively). VT(2) overestimated MLSS by 10.9 (6.3)% .VO(2max), which was significantly higher than VT(1) [+21.4 (5.6)% .VO(2max); p<0.01]. CP calculated from a given range of exhaustion times does not correspond to MLSS...
  59. ncbi Effects of 28 days of beta-alanine and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion
    R F Zoeller
    Department of Exercise Science and Health Promotion, Florida Atlantic University, Davie, FL, USA
    Amino Acids 33:505-10. 2007
    ..No significant group effects were found. However, within groups, a significant time effect was observed for CrBa on 5 of the 8 parameters measured. These data suggest that CrBA may potentially enhance endurance performance...
  60. ncbi Reproducibility of ventilation of thresholds in trained cyclists during ramp cycle exercise
    S B Weston
    Exercise Science Research Laboratory, School of Physiotherapy and Exercise Science, Griffith University, Queensland, Australia
    J Sci Med Sport 4:357-66. 2001
    ..However, determinations of VT1 are less reliable. Additionally, ventilation thresholds are more reliably described using absolute rather than relative VO2 values...
  61. ncbi Exercise can be pyrogenic in humans
    Carl D Bradford
    School of Physical Education, University of Otago, P O Box 56, Dunedin, New Zealand
    Am J Physiol Regul Integr Comp Physiol 292:R143-9. 2007
    ....
  62. ncbi Effect of high-intensity interval training and detraining on extra VO2 and on the VO2 slow component
    A Marles
    EA 3608 Physical activity, Sport and Health, Faculty of Sport Sciences and Physical Education, University of Lille 2, Lille, France
    Eur J Appl Physiol 99:633-40. 2007
    ..Moreover, the fact that extra VO2 did not change after detraining could indicate that this improvement may remain after the loss of other adaptations...
  63. ncbi Relationship between %HRmax, %HR reserve, %VO2max, and %VO2 reserve in elite cyclists
    Joseph Lounana
    Unit for Exercise Biology and Sports Medicine, University Hospital Center, Amiens, France
    Med Sci Sports Exerc 39:350-7. 2007
    ..To evaluate the relations between %HRmax, %HRR, %VO2max, and %VO2R in elite cyclists and to check whether the intensity scale recommended by ACSM in its 1998 position stand is also applicable to this specific population...
  64. ncbi Determinants of maximal oxygen uptake in moderate acute hypoxia in endurance athletes
    Pascal Mollard
    Laboratoire Réponses Cellulaires et Fonctionnelles à l Hypoxie, Universite Paris 13, 74 rue Marcel Cachin, EA2363, ARPE, 93017 Bobigny Cedex, France
    Eur J Appl Physiol 100:663-73. 2007
    ..VEmax at 4,500 m (2) the greater.QaO2max decrement in TS due to a lower Sa'O2max and unchanged .Qmax 3) the smaller increase in O2ERmax in TS, insufficient to compensate the decrease in .QaO2max...
  65. ncbi The development of rating of perceived exertion-based tests of physical working capacity
    Michelle Mielke
    Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska Lincoln, Lincoln, Nebraska, USA
    J Strength Cond Res 22:293-302. 2008
    ..Furthermore, the power outputs at the PWC(BORG) and PWC(OMNI) may be useful to estimate the VT noninvasively and without the need for expired gas analysis...
  66. ncbi Practical tests for monitoring performance, fatigue and recovery in triathletes
    Aaron J Coutts
    School of Leisure, Sport and Tourism, University of Technology, Sydney, Australia
    J Sci Med Sport 10:372-81. 2007
    ..There were weak significant correlations between weekly changes in 3 kmTT and 5BT (r=-0.37, p<0.01). The DALDA and 5BT may be practical tests for assessing changes in performance, fatigue and recovery of endurance athletes...
  67. ncbi Effects of acute moderate hypoxia on anaerobic capacity in endurance-trained runners
    Birgit Friedmann
    Department of Internal Medicine VII Sports Medicine, University Hospital, Im Neuenheimer Feld 710, 69120, Heidelberg, Germany
    Eur J Appl Physiol 101:67-73. 2007
    ..The performance reduction during all-out exercise of short duration has to be attributed to the decrement in aerobic capacity...
  68. ncbi Plasma lactate accumulation is reduced during incremental exercise in untrained women compared with untrained men
    Charli Sargent
    Exercise Physiology Research Unit, Department of Physiology, University of Adelaide, Adelaide, SA, Australia
    Eur J Appl Physiol 101:91-6. 2007
    ..While the basis of this sex difference is unknown, reduced plasma [La(-1)] during submaximal exercise in women may offset to some degree the endurance performance disadvantage of their lower VO2peak...
  69. ncbi Neuromuscular and circulatory adaptation during combined arm and leg exercise with different maximal work loads
    Thibault Brink-Elfegoun
    Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden
    Eur J Appl Physiol 101:603-11. 2007
    ..In conclusion, these findings do not support the theory of the existence of a central governor (CG) that regulates circulation and neuronal output of skeletal muscles during maximal exercise...
  70. ncbi Endurance training guided individually by daily heart rate variability measurements
    Antti M Kiviniemi
    Department of Exercise and Medical Physiology, Verve Research, Kasarmintie 13, P O Box 404, 90101, Oulu, Finland
    Eur J Appl Physiol 101:743-51. 2007
    ..No significant differences were observed in the changes of VO(2peak) between the groups. We concluded that cardiorespiratory fitness can be improved effectively by using HRV for daily training prescription...
  71. ncbi The relationship between ventilatory and lactate thresholds in boys and men
    Cindy S Anderson
    Human Performance Laboratory, Ball State University, Muncie, Indiana, USA
    Res Sports Med 15:189-200. 2007
    ..min(-1)) and r = 0.82 for % peak VO(2) (P < 0.05) in boys and r = 0.87 (P < 0.05) and r = 0.60 (P > 0.05), respectively, in men. The mechanisms mediating VT and LT in children are not established fully and warrant further study...
  72. ncbi The talk test as a marker of exercise training intensity
    Carl Foster
    Department of Exercise and Sport Science, University of Wisconsin La Crosse, La Crosse, WI 54601, USA
    J Cardiopulm Rehabil Prev 28:24-30; quiz 31-2. 2008
    ..This study examined manipulations of either the VT or exercise protocol to test the hypothesis that the TT and VT are related in a robust way, adequate for exercise prescription...
  73. ncbi Critical velocity during continuous and intermittent exercises in children
    Serge Berthoin
    Laboratory of Human Movement Studies EA3608, Faculty of Sports Sciences and Physical Education, Lille 2 University, 9, rue de l université, Ronchin, France
    Eur J Appl Physiol 98:132-8. 2006
    ..CVc was significantly related to peakVO2, while a significant lower relationship was found between peakVO2 and CVi...
  74. ncbi Effect of different pedal rates on oxygen uptake slow component during constant-load cycling exercise
    T Migita
    Institute of Health and Sports Science, Kurume University, Kurume, Japan
    J Sports Med Phys Fitness 46:189-96. 2006
    ....
  75. ncbi Effect of ramp slope on ventilation thresholds and VO2peak in male cyclists
    S B Weston
    School of Physiotherapy and Exercise Science, Griffith University, Gold Coast, Queensland, Australia
    Int J Sports Med 23:22-7. 2002
    ..In addition, the WR measured at VT1, VT2 and VO(2)peak varies with the ramp slope and should be utilized cautiously when prescribing training or evaluating performance...
  76. ncbi Relationship between oxygenation in inactive biceps brachii muscle and hyperventilation during leg cycling
    H Ogata
    Laboratory of Exercise Physiology, Graduate School of Education, Hokkaido University, Kita ku, Sapporo City, Japan
    Physiol Res 56:57-65. 2007
    ..Thus, we concluded that decrease in oxygenation in inactive arm muscle is closely coupled with increase in the amount of hyperventilation...
  77. ncbi Physical activity patterns and exercise performance in cardiac transplant recipients
    Jonathan Myers
    Cardiovascular Division, Veterans Affairs Palo Alto Health Care System, Calif 94304, USA
    J Cardiopulm Rehabil 23:100-6. 2003
    ..Among the factors suggested to explain the reduced exercise tolerance in CTX recipients is deconditioning. Little is known about the relation between physical activity patterns and exercise test responses in CTX patients...
  78. ncbi Effects of ribose supplementation prior to and during intense exercise on anaerobic capacity and metabolic markers
    C Kerksick
    Exercise and Sport Nutrition Laboratory, Center for Exercise, Nutrition and Preventive Health Research, Dept of Health, Human Performance and Recreation, Baylor University, Waco, TX 76798 7313, USA
    Int J Sport Nutr Exerc Metab 15:653-64. 2005
    ..No significant interactions were observed for any performance or blood variables. D-ribose supplementation has no impact on anaerobic exercise capacity and metabolic markers after high-intensity cycling exercise...
  79. ncbi Prediction of time to exhaustion from blood lactate response during submaximal exercise in competitive cyclists
    A Sassi
    Human Performance Laboratory, S S Mapei, Via Don Minzoni, 34, 21053, Castellanza Varese, Italy
    Eur J Appl Physiol 97:174-80. 2006
    ..In conclusion, this study demonstrates that pTE is a valid and practical alternative to incremental tests and direct measures of endurance capacity requiring exhaustive efforts for the evaluation of competitive cyclists...
  80. ncbi Physiological predictors of performance in cross-country skiing from treadmill tests in male and female subjects
    P Larsson
    Department of Surgical and Perioperative Science, Sports Medicine, Department of Clinical Physiology, Umea University, Umea, Sweden
    Scand J Med Sci Sports 12:347-53. 2002
    ..Parameters measured or computed by metabolic gas measurements were the anaerobic threshold (AT), threshold of decompensated metabolic acidosis (TDMA), the exercise intensity where the Respiratory ..
  81. ncbi The ventilatory anaerobic threshold is related to, but is lower than, the critical power, but does not explain exercise tolerance at this workrate
    N Okudan
    Department of Physiology, Meram Faculty of Medicine, Selcuk University, Konya, Turkey
    J Sports Med Phys Fitness 46:15-9. 2006
    ..study was to investigate the relationships between critical power (CP), maximal aerobic power and the anaerobic threshold and whether exercise time to exhaustion and work at the CP can be used as an index in the determination of ..
  82. ncbi Calculation of additional (XS) V0(2) during incremental exercise
    Andrew M Jones
    Med Sci Sports Exerc 34:1859; author reply 1860. 2002
  83. ncbi A new pedaling design: the Rotor--effects on cycling performance
    Alfredo Santalla
    Universidad Alfonso X El Sabio, Madrid, Spain
    Med Sci Sports Exerc 34:1854-8. 2002
    ..To assess the effects of the Rotor (ROT), a new pedaling system that makes each pedal independent from the other so that cranks are no longer fixed at 180 degrees, on endurance cycling performance...
  84. ncbi Exercise intensity during off-road cycling competitions
    Franco Impellizzeri
    Laboratorio di Fisologia, Sport Service MAPEI, Castellanza, Varese, Italy
    Med Sci Sports Exerc 34:1808-13. 2002
    ..This study was designed to quantify and describe the intensity profile of cross-country mountain-biking races using heart rate (HR) recorded during competitions...
  85. ncbi Method of lactate elevation does not affect the determination of the lactate minimum
    Mark F Smith
    Department of Sport and Exercise Science, Canterbury Christ Church University College, United Kingdom
    Med Sci Sports Exerc 34:1744-9. 2002
    ..The aim of the study was to examine the effects of different lactate elevation protocols on the determination of the lactate minimum (Lac(min)) point...
  86. ncbi Physiological variables at lactate threshold under-represent cycling time-trial intensity
    R W Kenefick
    University of New Hampshire, Department of Kinesiology, Exercise Physiology Laboratory, Durham, New Hampshire 03824, USA
    J Sports Med Phys Fitness 42:396-402. 2002
    ..Prior work indicates however, that this may not be true during a cycling time-trial (TT). This investigation sought to compare physiological variables during a 20-k TT with those corresponding to the athlete's LT...
  87. ncbi Relationship of exercise test variables to cycling performance in an Ironman triathlon
    Paul B Laursen
    School of Human Moement Studies, The University of Queensland, Brisbane, Australia
    Eur J Appl Physiol 87:433-40. 2002
    ..triathletes during the cycling portion of an Ironman triathlon, and, secondly, to examine the anaerobic threshold and its relationship to this performance...
  88. ncbi Adaptations to endurance training in the healthy elderly: arm cranking versus leg cycling
    S Pogliaghi
    Laboratorio di Fisiologia dell esercizio, Facoltà di Scienze Motorie, Universita degli Studi di Verona, Via Casorati, 43, 37131 Verona, VR, Italy
    Eur J Appl Physiol 97:723-31. 2006
    ..The other half is non-specific since it influences also the alternative exercise modality, and is probably due to central adaptations...
  89. pmc Lactic acidosis, potassium, and the heart rate deflection point in professional road cyclists
    A Lucia
    Departamento de Ciencias Morfológicas y Fisiología, Universidad Europea de Madrid, Madrid, Spain
    Br J Sports Med 36:113-7. 2002
    ..To determine the influence of lactic acidosis, the Bohr effect, and exercise induced hyperkalaemia on the occurrence of the heart rate deflection point (HRDP) in elite (professional) cyclists...
  90. ncbi Estimation of the exercise ventilatory compensation point by the analysis of the relationship between minute ventilation and heart rate
    Paolo Onorati
    Dipartimento di Medicina Clinica, Servizio di Fisiopatologia Respiratoria, Universita La Sapienza, Viale dell Universita 37, Rome, Italy
    Eur J Appl Physiol 104:87-94. 2008
    ..VCP occurred at the same percentage of peak V'O(2) in both protocols. The changes in the V'(E) versus HR slope during incremental exercise can be used to detect the VCP as alternative to the ventilatory equivalents method...
  91. ncbi Significant ventilatory functional restriction in adolescents with mild or moderate scoliosis during maximal exercise tolerance test
    Carlos Barrios
    Department of Surgery, Valencia University Medical School, Valencia, Spain
    Spine (Phila Pa 1976) 30:1610-5. 2005
    ..A prospective evaluation of cardiopulmonary tolerance to maximal exercise in adolescent idiopathic scoliosis...
  92. ncbi [The effect of controlled and uncontrolled dynamic lower extremity training in the rehabilitation of patients with chronic obstructive pulmonary disease]
    Janos Varga
    Szegedi Tudomanyegyetem, Szent Györgyi Albert Orvos es Gógyszerésztudományi Centrum, Általános Orvostudományi Kar, Tüdogyógyászati Tanszék, Csongrád Megyei Onkormányzat Mellkasi Betegségek Szakkórháza, I Tüdoosztály, Deszk
    Orv Hetil 146:2249-55. 2005
    ..Pulmonary rehabilitation has become a part of the integrated management of patients with chronic obstructive pulmonary disease (COPD). The lower extremity dynamic training has been proved to be the most effective element of the program...
  93. ncbi Erythropoietin improves anemia exercise tolerance and renal function and reduces B-type natriuretic peptide and hospitalization in patients with heart failure and anemia
    Alberto Palazzuoli
    Cardiology Section, Department of Internal Medicine and Metabolic Diseases, Le Scotte Hospital, University of Siena, Siena, Italy
    Am Heart J 152:1096.e9-15. 2006
    ..We report a randomized, double-blind, placebo-controlled study of the combination of s.c. EPO and oral iron versus oral iron alone in patients with anemia and resistant CHF...
  94. ncbi Homograft insertion for pulmonary regurgitation after repair of tetralogy of fallot improves cardiorespiratory exercise performance
    B Eyskens
    Department of Pediatric and Congenital Cardiology, University Hospital Gasthuisberg, Leuven, Belgium
    Am J Cardiol 85:221-5. 2000
    ..Cardiopulmonary exercise performance was evaluated by determination of the ventilatory anaerobic threshold (VAT) and by the steepness of the slope of oxygen uptake versus exercise intensity (SVO2)...
  95. ncbi [Cardiopulmonary exercise capacity increases after interventional ASD-closure]
    M Weber
    Kerckhoff Klinik, Abteilung fur Kardiologie, Benekestrasse 2 8, 61231 Bad Nauheim, Germany
    Z Kardiol 93:209-15. 2004
    ..The aim of this study was to evaluate exercise capacity as achieved by ergospirometry in adult patients with an ASD at baseline and in the long-term following transcatheter closure...
  96. ncbi Effects of antecedent hypoglycemia on subsequent counterregulatory responses to exercise
    S N Davis
    Department of Medicine, Vanderbilt University School of Medicine and Nashville Veteran Affairs Medical Center, Tennessee 37232, USA
    Diabetes 49:73-81. 2000
    ..On day 2, subjects underwent 90 min of exercise on a static cycle ergometer at 80% of their anaerobic threshold (approximately 50% VO2max)...
  97. ncbi [Atrial septal defect associated with mitral valve prolapse--prevalence and clinical significance]
    Elzbieta Suchon
    Klinika Chorób Serca i Naczyń, Instytutu Kardiologii Collegium Medicum, Uniwersytetu Jagiellonskiego w Krakowie
    Przegl Lek 61:636-9. 2004
    ..High incidence of mitral valve prolapse (MVP) associated with atrial septal defect (ASD) has been reported. The study aimed to evaluate the prevalence, etiology and clinical significance of MVP in patients with ASD...
  98. ncbi [Cardiopulmonary exercise capacity in adult patients with atrial septal defect]
    Elzbieta Suchon
    Klinika Chorób Serca i Naczyń IK CMUJ ul Pradnicka 80, 31 202 Krakow
    Przegl Lek 59:747-51. 2002
    ..analysed: peak oxygen uptake--(VO2 peak; ml/kg/min), VO2 peak expressed as % of predicted value--(VO2 %N), anaerobic threshold--(AT; % VO2 max), ventilatory equivalent for carbon dioxide--(VE/VCO2), end-tidal carbon dioxide pressure--(..
  99. ncbi Regional distribution of lung perfusion and ventilation at rest and during steady-state exercise after unilateral lung transplantation
    D J Ross
    Division of Pulmonary Medicine, Cedars Sinai Medical Center UCLA School of Medicine 90048
    Chest 104:130-5. 1993
    Cardiopulmonary exercise testing has previously demonstrated a reduced maximum oxygen uptake and anaerobic threshold, as well as abnormal wasted ventilation fraction and gas exchange after unilateral lung transplantation...
  100. ncbi Airflow limitation and breathing strategy in congestive heart failure patients during exercise
    C Andrew Schroeder
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Respiration 70:137-42. 2003
    ..Congestive heart failure (CHF) patients experience dyspnea on exertion and therefore have decreased exercise tolerance...
  101. pmc Intensity level for exercise training in fibromyalgia by using mathematical models
    Maria Carolina D Lemos
    Federal University of Sao Paulo, Sao Paulo, Brazil
    BMC Musculoskelet Disord 11:54. 2010
    ..The objective of this paper was to determine how age-predicted heart rate formulas can be used with fibromyalgia syndrome populations as well as to find out which mathematical models are more accurate to control exercise intensity...

Research Grants23

  1. Weight-loss, Exercise, and Oxidative Capacity in Obesity
    Matthew Harber; Fiscal Year: 2005
    ..lean subjects. The obese women will then be reevaluated following 12% weight loss (through diet only or diet plus exercise) to examine the influence of weight-loss with or without exercise on these parameters. ..
  2. Pathophysiology of Heart Failure with a Normal Ejection Fraction in the Elderly
    Mathew S Maurer; Fiscal Year: 2010
    ..Principle measurements will include six minute walk, maximal oxygen consumption and ventilatory anaerobic threshold by expired gas analysis;blood volume analysis, mesaures of renal function, health status by standardized ..
  3. GROWTH HORMONE FOR PEDIATRIC DILATED CARDIOMYOPATHY
    Jane Newburger; Fiscal Year: 2001
    ..b) Measures of functional status, including anaerobic threshold, assessed by exercise testing, and parent perception of functional status, assessed by score on the parent ..
  4. Exercise for Mental Health: Does Exercise Make People Feel Better?
    Panteleimon Ekkekakis; Fiscal Year: 2003
    ..The immediate anticipated benefit of this research is the development of physical activity public health recommendations that incorporate affect as a fundamental consideration. ..
  5. Regulation of lipolysis by nitric oxide and adenosine
    Robert Hickner; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  6. EXERCISE INTOLERANCE IN ELDERLY DIASTOLIC HEART FAILURE
    Dalane Kitzman; Fiscal Year: 2004
    ..phase-contrast gradient-echo magnetic resonance imaging (MRI); maximal oxygen consumption and ventilatory anaerobic threshold by expired gas analysis; and quality of life by standardized questionnaires, and LV volumes and mass by MR1...
  7. Exercise, muscle nutritive blood flow and eNOS in aging
    Robert Hickner; Fiscal Year: 2003
    ..abstract_text> ..
  8. Reduction in CVD risk in children by physical activity
    Robert C Hickner; Fiscal Year: 2010
    ....
  9. Age, VEGF, and skeletal muscle capillarization in humans
    TIMOTHY GAVIN; Fiscal Year: 2003
    ..Data obtained from these studies will provide necessary information for future R01 funding. Findings will be important as little is known concerning the effects of aging on neovascularization potential in humans. ..
  10. CHF TRIAL INVESTIGATING OUTCOMES OF EXERCISE TRAINING
    Dalane Kitzman; Fiscal Year: 2007
    ..abstract_text> ..
  11. VESTIBULOSYMPATHETIC REFLEXES IN HUMANS
    CHESTER RAY; Fiscal Year: 2001
    ....
  12. WAGES: Workplace Activity for Employee Goal Setting
    RODNEY DISHMAN; Fiscal Year: 2006
    ..The project will implement and rigorously evaluate a multilevel physical activity intervention that has potential for broad application to workplace health promotion. ..
  13. Proteomics: Inactivity-induced muscle insulin resistance
    Frank Booth; Fiscal Year: 2002
    ..Outcomes of this proposal will better establish that healthy active skeletal muscles interact with other organ systems to prevent the metabolic disorders of type 2 diabetes, atherosclerosis, and obesity. ..
  14. Ginger Control of Chemotherapy Induced Nausea and Emesis
    Suzanna Zick; Fiscal Year: 2004
    ..Participants will be followed for 48 hours after infusion in order to assess frequency and severity of nausea and vomiting. Baseline and 48 hour post chemotherapy labs will be used to assess safety profile of ginger. ..
  15. Failed rescue of old skeletal muscle from atrophy
    Frank Booth; Fiscal Year: 2004
    ..Identifying the inappropriately expressed mRNAs associated with failed muscle regrowth of old muscles will permit a more scientifically-based growth factor rescue of old atrophied muscle. ..
  16. Disability and Aerobic Capacity in SLE
    RANDALL KEYSER; Fiscal Year: 2002
    ..Excessive fatigue is disabling in up to 80 percent of those with SLE. This research holds promise for improved evaluation and treatment of SLE fatigue and may have implications for adherence to the Americans with Disabilities Act. ..
  17. SATELLITE STEM CELL BIOLOGY
    Frank Booth; Fiscal Year: 2008
    ..The outcomes of the research will provide a more scientific basis to devise therapies to prevent and treat sarcopenia and physical frailty. ..
  18. Exercise, amenorrhea, stress & bone health in adolescent
    JOSEPHINE KASA VUBU; Fiscal Year: 2007
    ..Our goal will be to identify early markers of declining gonadotropin function and bone health in postpubertal young women as they improve cardiovascular capacity ..
  19. Post Coronary Bypass Atrial Arrhythmic Prediction Rule
    Rod Passman; Fiscal Year: 2006
    ..This project will be an integral part of the candidate?s career development plan and his maturation as an epidemiologist, cardiac electrophysiologist, and clinical investigator. ..
  20. VESTIBULOSYMPATHETIC REFLEXES IN HUMANS
    CHESTER RAY; Fiscal Year: 2005
    ..The design of these studies will increase our understanding of how the vestibular system contributes to orthostatic blood pressure regulation in humans. ..
  21. Diet and Exercise: Race, Postmenopause and Metabolism
    ALICE RYAN; Fiscal Year: 2005
    ..These findings may provide a rationale for targeting specific populations of women who might improve glucose and fat metabolism more from the addition of exercise to hypocaloric weight loss than weight loss alone. ..
  22. EXERCISE INDUCED GROWTH OF SKELETAL MUSCLE
    Frank Booth; Fiscal Year: 2003
    ..Elucidation of the mechanisms signaling skeletal muscle growth may lead to drugs, gene therapy, or other countermeasures against skeletal muscle wasting in individuals for whom exercise is perhaps impossible. ..