gastric emptying

Summary

Summary: The evacuation of food from the stomach into the duodenum.

Top Publications

  1. ncbi Does postprandial coffee intake enhance gastric emptying?: a crossover study using continuous real time 13C breath test (BreathID system)
    Keiko Akimoto
    Gastroenterology Division, Yokohama City University School of Medicine, Yokohama, Japan
    Hepatogastroenterology 56:918-20. 2009
  2. ncbi Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)
    Moritz N Wente
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany
    Surgery 142:761-8. 2007
  3. pmc Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying
    Sara Janssen
    Department of Pathophysiology, Translational Research Center for Gastrointestinal Disorders, Catholic University of Leuven, 3000 Leuven, Belgium
    Proc Natl Acad Sci U S A 108:2094-9. 2011
  4. pmc Clinical features of idiopathic gastroparesis vary with sex, body mass, symptom onset, delay in gastric emptying, and gastroparesis severity
    Henry P Parkman
    Gastroenterology Section, Temple University, Philadelphia, Pennsylvania 19140, USA
    Gastroenterology 140:101-15. 2011
  5. ncbi Postoperative ileus is maintained by intestinal immune infiltrates that activate inhibitory neural pathways in mice
    Wouter J de Jonge
    Department of Gastroenterology and Hepatology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Gastroenterology 125:1137-47. 2003
  6. pmc Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects
    Jing Ma
    University of Adelaide, Discipline of Medicine, Royal Adelaide Hospital, North Terr, Adelaide SA 5000, Australia
    Am J Physiol Gastrointest Liver Physiol 296:G735-9. 2009
  7. pmc Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
    Michael A Nauck
    Diabeteszentrum Bad Lauterberg, Bad Lauterberg, Germany
    Diabetes 60:1561-5. 2011
  8. ncbi Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes
    Michael Horowitz
    University of Adelaide Discipline of Medicine, Royal Adelaide Hospital, Adelaide, Australia
    Diabetes Res Clin Pract 97:258-66. 2012
  9. ncbi Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans
    Tongzhi Wu
    Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Australia
    Am J Clin Nutr 95:78-83. 2012
  10. ncbi Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia
    Giovanni Sarnelli
    Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    Am J Gastroenterol 98:783-8. 2003

Detail Information

Publications348 found, 100 shown here

  1. ncbi Does postprandial coffee intake enhance gastric emptying?: a crossover study using continuous real time 13C breath test (BreathID system)
    Keiko Akimoto
    Gastroenterology Division, Yokohama City University School of Medicine, Yokohama, Japan
    Hepatogastroenterology 56:918-20. 2009
    ..The aim of this study was to determine whether there was a correlation between coffee intake and gastric emptying using a novel non-invasive technique for measuring gastric emptying with a continuous real time 13C breath ..
  2. ncbi Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)
    Moritz N Wente
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany
    Surgery 142:761-8. 2007
    Delayed gastric emptying (DGE) is one of the most common complications after pancreatic resection...
  3. pmc Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying
    Sara Janssen
    Department of Pathophysiology, Translational Research Center for Gastrointestinal Disorders, Catholic University of Leuven, 3000 Leuven, Belgium
    Proc Natl Acad Sci U S A 108:2094-9. 2011
    ..to investigate whether T2R-agonists affect (i) ghrelin release via α-gustducin and (ii) food intake and gastric emptying via the release of ghrelin...
  4. pmc Clinical features of idiopathic gastroparesis vary with sex, body mass, symptom onset, delay in gastric emptying, and gastroparesis severity
    Henry P Parkman
    Gastroenterology Section, Temple University, Philadelphia, Pennsylvania 19140, USA
    Gastroenterology 140:101-15. 2011
    ..We studied characteristics of patients with IG enrolled in the National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Clinical Research Consortium Registry...
  5. ncbi Postoperative ileus is maintained by intestinal immune infiltrates that activate inhibitory neural pathways in mice
    Wouter J de Jonge
    Department of Gastroenterology and Hepatology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Gastroenterology 125:1137-47. 2003
    ..We aimed to study its pathophysiology in a murine model by determining gastric emptying after manipulation of the small intestine.
  6. pmc Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects
    Jing Ma
    University of Adelaide, Discipline of Medicine, Royal Adelaide Hospital, North Terr, Adelaide SA 5000, Australia
    Am J Physiol Gastrointest Liver Physiol 296:G735-9. 2009
    ..We studied blood glucose, plasma levels of insulin, GLP-1, and GIP, and gastric emptying (by a breath test) in 7 healthy humans after intragastric infusions of 1) 50 g sucrose in water to a total ..
  7. pmc Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
    Michael A Nauck
    Diabeteszentrum Bad Lauterberg, Bad Lauterberg, Germany
    Diabetes 60:1561-5. 2011
    Glucagon-like peptide (GLP)-1 lowers postprandial glycemia primarily through inhibition of gastric emptying. We addressed whether the GLP-1-induced deceleration of gastric emptying is subject to rapid tachyphylaxis and if so, how this ..
  8. ncbi Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes
    Michael Horowitz
    University of Adelaide Discipline of Medicine, Royal Adelaide Hospital, Adelaide, Australia
    Diabetes Res Clin Pract 97:258-66. 2012
    ..Liraglutide reduces bodyweight in patients with type 2 diabetes mellitus (T2DM). This study aimed to investigate the mechanisms underlying this effect...
  9. ncbi Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans
    Tongzhi Wu
    Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Australia
    Am J Clin Nutr 95:78-83. 2012
    ..can stimulate glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), slow gastric emptying, and reduce postprandial glycemic excursions...
  10. ncbi Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia
    Giovanni Sarnelli
    Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    Am J Gastroenterol 98:783-8. 2003
    The relationship between functional dyspepsia and delayed gastric emptying of solids or liquids is still unclear...
  11. ncbi Comparison of gastric emptying and plasma ghrelin levels in patients with functional dyspepsia and non-erosive reflux disease
    Tomotaka Shindo
    Department of Internal Medicine, Division of Gastroenterology, Nippon Medical School, Tokyo 113 8602, Japan
    Digestion 79:65-72. 2009
    ..Thus, this study aims to evaluate the correlation between gastric emptying and ghrelin levels as possible candidate factors for gastric motility in these diseases.
  12. ncbi Effects of fat on gastric emptying of and the glycemic, insulin, and incretin responses to a carbohydrate meal in type 2 diabetes
    Diana Gentilcore
    University of Adelaide, Department of Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia 5000, Australia
    J Clin Endocrinol Metab 91:2062-7. 2006
    b>Gastric emptying (GE) is a major determinant of postprandial glycemia. Because the presence of fat in the small intestine inhibits GE, ingestion of fat may attenuate the glycemic response to carbohydrate.
  13. ncbi JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses food intake and gastric emptying with the elevation of plasma peptide YY and glucagon-like peptide-1 in a dietary fat-dependent manner
    Takahiro Hata
    Japan Tobacco Inc, Central Pharmaceutical Research Institute, Takatsuki, Osaka 569 1125, Japan
    J Pharmacol Exp Ther 336:850-6. 2011
    ..phenyl}acetyloxymethyl)-2-phenylmalonate (JTT-130), a novel intestine-specific MTP inhibitor, on food intake, gastric emptying, and gut peptides using Sprague-Dawley rats fed 3.1% fat, 13% fat, or 35% fat diets...
  14. pmc Intragastric infusion of denatonium conditions flavor aversions and delays gastric emptying in rodents
    John I Glendinning
    Department of Biological Sciences, Barnard College, Columbia University, 3009 Broadway, New York, NY 10027, USA
    Physiol Behav 93:757-65. 2008
    ..IG) infusion of denatonium (a ligand for T2R receptors) would condition a flavor aversion and/or delay gastric emptying. Four experiments tested for post-oral responses to denatonium in rodents...
  15. ncbi How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study
    M Willems
    Julius Centre for General Practice and Patient Oriented Research, University Medical Centre, Utrecht, The Netherlands
    Dig Dis Sci 46:2256-62. 2001
    ..Delayed gastric emptying is present in nearly 40% of patients...
  16. ncbi Pathophysiology and treatment of functional dyspepsia
    Jan Tack
    Division of Gastroenterology, Department of Internal Medicine, University Hospital Gasthuisberg, University of Leuven, Belgium
    Gastroenterology 127:1239-55. 2004
  17. ncbi Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice
    Gabriella Aviello
    Endocannabinoid Research Group, Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
    J Mol Med (Berl) 86:413-22. 2008
    b>Gastric emptying regulates food intake. Oleoylethanolamide (OEA), an endogenous acylethanolamide chemically related to the endocannabinoid anandamide, inhibits food intake, but its effect on gastric emptying is unknown...
  18. ncbi Delayed gastric emptying is related to cardiovascular autonomic neuropathy in Chinese patients with type 2 diabetes
    R W Bian
    Diabetes Care and Research Center, Jiangsu Province Institute of Geriatrics, Nanjing, China
    Acta Gastroenterol Belg 74:28-33. 2011
    Delayed gastric emptying (DGE) is the commonest gastrointestinal (GI) complication in type 2 diabetes. We aimed to evaluate the association between DGE and cardiovascular autonomic neuropathy (CAN) in type 2 diabetes.
  19. pmc The impact of food viscosity on eating rate, subjective appetite, glycemic response and gastric emptying rate
    Yong Zhu
    Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA
    PLoS ONE 8:e67482. 2013
    ..001), higher plasma concentration of glucose (P<0.001) and delayed gastric emptying as revealed by the acetaminophen absorption test (P<0.001)...
  20. ncbi Fast pouch emptying, delayed small intestinal transit, and exaggerated gut hormone responses after Roux-en-Y gastric bypass
    C Dirksen
    Department of Endocrinology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark
    Neurogastroenterol Motil 25:346-e255. 2013
    ..Roux-en-Y gastric bypass (RYGB) causes extensive changes in gastrointestinal anatomy and leads to reduced appetite and large weight loss, which partly is due to an exaggerated release of anorexigenic gut hormones...
  21. ncbi Measurement of gastric emptying by radiopaque markers in patients with diabetes: correlation with scintigraphy and upper gastrointestinal symptoms
    E A Olausson
    Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    Neurogastroenterol Motil 25:e224-32. 2013
    Scintigraphy, the gold standard to measure gastric emptying, is expensive and not widely available...
  22. ncbi Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients
    Dorit Samocha-Bonet
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Sydney 2010, Australia
    J Nutr 141:1233-8. 2011
    ..These findings suggest that glutamine may be a novel agent for stimulating GLP-1 concentration and limiting postprandial glycemia in type 2 diabetes...
  23. ncbi Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy: a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomy
    Manabu Kawai
    Second Department of Surgery, Wakayama Medical University School of Medicine, Wakayama, Japan
    Ann Surg 253:495-501. 2011
    ..trial (RCT) whether pylorus-resecting pancreatoduodenectomy (PrPD) with preservation of nearly the entire stomach reduces the incidence of delayed gastric emptying (DGE) compared with pylorus-preserving pancreatoduodenectomy (PpPD).
  24. ncbi Impact of rikkunshito, an herbal medicine, on delayed gastric emptying in profoundly handicapped patients
    Hisayoshi Kawahara
    Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, 840 Murodo cho Izumi, Osaka, 594 1101, Japan
    Pediatr Surg Int 25:987-90. 2009
    Rikkunshito is used to treat functional dyspepsia in adults. This study investigated the effects of rikkunshito on delayed gastric emptying in handicapped patients.
  25. pmc Cold ambient temperature reverses abdominal surgery-induced delayed gastric emptying and decreased plasma ghrelin levels in rats
    Andreas Stengel
    CURE Digestive Diseases Research Center, Center for Neurobiology of Stress, Department of Medicine, Digestive Diseases Division at the University of California Los Angeles, and VA Greater Los Angeles Health Care System, CA 90073, USA
    Peptides 31:2229-35. 2010
    ..through brainstem thyrotropin-releasing hormone (TRH) signaling influences abdominal surgery-induced delayed gastric emptying (GE) in fasted rats...
  26. ncbi Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia?
    N J Talley
    Department of Medicine, University of Sydney, Nepean Hospital, Penrith, Australia
    Am J Gastroenterol 96:1422-8. 2001
    ..sex and severe fullness and vomiting have been reported to be strong independent predictors of slow solid gastric emptying. We aimed to determine if symptom patterns or severity could identify those with abnormal gastric emptying ..
  27. ncbi Etiology of portal hypertension may influence gastrointestinal transit
    R Sadik
    Division of Gastroenterology, Institute of Internal Medicine, Sahlgrenska University Hospital, University of Goteborg, Goteborg, Sweden
    Scand J Gastroenterol 38:1039-44. 2003
    ..We have studied gastric emptying. small-bowel transit and colonic transit in patients with portal hypertension...
  28. ncbi Electroacupuncture accelerates gastric emptying in association with changes in vagal activity
    Hui Ouyang
    Division of Gastroenterology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0632, USA
    Am J Physiol Gastrointest Liver Physiol 282:G390-6. 2002
    ..a disorder with a lack of treatment options and this study investigated the effect of electroacupuncture on gastric emptying and involved mechanisms...
  29. ncbi Electroacupuncture improves restraint stress-induced delay of gastric emptying via central glutaminergic pathways in conscious rats
    Masahiro Iwa
    Department of Surgery, Duke University and Durham Veterans Affairs Medical Center, Surgical Service 112, 508 Fulton Street, NC 27705, USA
    Neurosci Lett 399:6-10. 2006
    ..investigated the effects of electroacupuncture (EA) at ST-36 (Zusanli; lower limb) on stress-induced delay of gastric emptying. Solid food gastric emptying in 90 min was significantly delayed by restraint stress (27.3 +/- 2...
  30. ncbi Effects of body positions on gastric emptying with enteral nutrition: a crossover study using a continuous real time 13C breath test (BreathID system)
    Tamon Ikeda
    Gastroenterology Division, Yokohama City University Hospital, 3 9 Fukuura, Kanazawa Ku, Yokohama, 236 0004, Japan
    Hepatogastroenterology 55:1905-7. 2008
    The aim of this study was to determine whether there was a correlation between body positions and gastric emptying, using a novel non-invasive technique for measuring gastric emptying with a continuous real time 13C breath test (BreathID ..
  31. ncbi Early effects of peppermint oil on gastric emptying: a crossover study using a continuous real-time 13C breath test (BreathID system)
    Masahiko Inamori
    Gastroenterology Division, Yokohama City University, 3 9 Fukuura, Kanazawa Ku, Yokohama, 236 0004, Japan
    J Gastroenterol 42:539-42. 2007
    The aim of this study was to determine whether there was a correlation between peppermint oil and gastric emptying by using a novel noninvasive technique for measuring gastric emptying with a continuous real-time (13)C breath test (..
  32. ncbi Aperitif effects on gastric emptying: a crossover study using continuous real-time 13C breath test (BreathID System)
    M Inamori
    Gastroenterology Division, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, 236 0004, Japan
    Dig Dis Sci 54:816-8. 2009
    The aim of this study was to determine whether there is a correlation between aperitif and gastric emptying. Ten healthy male volunteers participated in this randomized, two-way crossover study...
  33. pmc Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease
    James G Greene
    Department of Neurology, Emory University School of Medicine, 505H Whitehead Biomedical Research Bldg, 615 Michael St, Atlanta, GA 30322, USA
    Exp Neurol 218:154-61. 2009
    ..Symptoms of GI dysmotility in PD include early satiety and weight loss from delayed gastric emptying and constipation from impaired colonic transit...
  34. ncbi Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans
    Kristiina R Juvonen
    Department of Clinical Nutrition, Food and Health Research Centre, School of Public Health and Clinical Nutrition, University of Kuopio, 70211 Kuopio, Finland
    J Nutr 139:461-6. 2009
    ..009) than the beverage with high-viscosity oat bran. Gastric emptying as measured by paracetamol absorption was also faster (P = 0...
  35. pmc Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia
    J Tack
    Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    Gut 52:1271-7. 2003
    ..Impaired gastric accommodation is a major pathophysiological mechanism in functional dyspepsia. The aim of the present work was to assess a satiety drinking test in the evaluation of accommodation in health and dyspepsia...
  36. ncbi High-viscosity liquid meal accelerates gastric emptying
    Y Shimoyama
    Department of Endoscopy and Endoscopic Surgery, Gunma University Hospital, Gunma, Japan
    Neurogastroenterol Motil 19:879-86. 2007
    ..We investigated the influence of the viscosity of an elemental formula on gastric emptying. Eleven healthy volunteers underwent three tests at intervals of >1 week...
  37. ncbi Endogenous glucagon-like peptide-1 slows gastric emptying in healthy subjects, attenuating postprandial glycemia
    Adam M Deane
    Disciplines of Anaesthesia and Intensive Care, University of Adelaide, Adelaide, South Australia 5005 Australia
    J Clin Endocrinol Metab 95:215-21. 2010
    The role of glucagon-like peptide-1 (GLP-1) in the regulation of gastric emptying is uncertain. The aim of this study was to determine the effects of endogenous GLP-1 on gastric emptying, glucose absorption, and glycemia in health.
  38. pmc Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors
    Khe T C Tran
    Department of General Surgery, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Surg 240:738-45. 2004
    ..the results of pylorus-preserving pancreaticoduodenectomy (PPPD) equal those of the standard Whipple (SW) operation, especially with respect to duration of surgery, blood loss, hospital stay, delayed gastric emptying (DGE), and survival.
  39. pmc Effects of a protein preload on gastric emptying, glycemia, and gut hormones after a carbohydrate meal in diet-controlled type 2 diabetes
    Jing Ma
    Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia
    Diabetes Care 32:1600-2. 2009
    We evaluated whether a whey preload could slow gastric emptying, stimulate incretin hormones, and attenuate postprandial glycemia in type 2 diabetes.
  40. ncbi Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
    Juris J Meier
    Department of Medicine I, St Josef Hospital, Ruhr University, Bochum, Germany
    Gastroenterology 130:44-54. 2006
    ..However, the acute effects of GLP-2 on gastric functions as well as on glucose and lipid homeostasis in humans are less well characterized...
  41. ncbi Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men
    E Naslund
    Department of Surgery, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden
    Am J Clin Nutr 68:525-30. 1998
    ..As a marker for gastric emptying, 1.5 g acetaminophen was given at the start of the meal...
  42. ncbi Gastric emptying, gastric secretion and enterogastrone response after administration of milk proteins or their peptide hydrolysates in humans
    Jose A L Calbet
    Copenhagen Muscle Research Center, Rigshospitalet, Copenhagen, Denmark
    Eur J Nutr 43:127-39. 2004
    The influence of protein fractionation on gastric emptying and rate of appearance of their constituent amino acids in peripheral blood remains unknown.
  43. ncbi Electroacupuncture accelerates solid gastric emptying and improves dyspeptic symptoms in patients with functional dyspepsia
    Sanping Xu
    Division of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Dig Dis Sci 51:2154-9. 2006
    ..aims of this study were to investigate the effects of electroacupuncture (EA) at ST36 and PC6 points on solid gastric emptying and dyspeptic symptoms in patients with functional dyspepsia...
  44. ncbi Tests of gastric neuromuscular function
    Henry P Parkman
    Gastroenterology Section, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Gastroenterology 136:1526-43. 2009
    ..These symptoms can be associated with alterations in the rates of gastric emptying, impaired accommodation, heightened gastric sensation, or alterations in gastric myoelectrical function and ..
  45. ncbi Gastric sensorimotor functions and hormone profile in normal weight, overweight, and obese people
    Maria I Vazquez Roque
    Clinical Enteric Neuroscience Translational and Epidemiological Research Program, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Gastroenterology 131:1717-24. 2006
    ..The aim of this study was to compare gastric volumes, emptying, maximum tolerated volumes, postchallenge symptoms, and selected gut hormones in normal, overweight, or obese healthy volunteers...
  46. ncbi An extensively hydrolysed cow's milk formula improves clinical symptoms of gastroesophageal reflux and reduces the gastric emptying time in infants
    A Garzi
    Pediatric Surgery Medicine and Surgery Department Siena University, Siena, Italy
    Allergol Immunopathol (Madr) 30:36-41. 2002
    ..About 20 % of infants fed with breast-milk substitutes suffer from Gastro Esophageal Reflux (GER) and 1/3 of them also show Cow's Milk Allergy (CMA) symptoms...
  47. ncbi Postoperative evaluation of function-preserving gastrectomy for early gastric cancer
    Eiji Nomura
    Department of General and Gastroenterological Surgery, Osaka Medical College, 2 7, Daigaku machi, Takatsuki, Osaka 569 8686, Japan
    Hepatogastroenterology 50:2246-50. 2003
    ..We evaluated the efficacy of the following three surgical options in gastrectomy for early gastric cancer; 1) reduction of the extent of gastrectomy, 2) preservation of the vagal nerve, and 3) preservation of the pylorus...
  48. ncbi Measurements of gastric emptying of low- and high-nutrient liquids using 3D ultrasonography and scintigraphy in healthy subjects
    D Gentilcore
    Royal Adelaide Hospital, University of Adelaide, Adelaide, SA, Australia
    Neurogastroenterol Motil 18:1062-8. 2006
    Scintigraphy represents the 'gold standard' for the measurement of gastric emptying. Recent studies suggest that three-dimensional (3D) ultrasonography may allow a precise measure of gastric emptying, given the capacity for accurate ..
  49. ncbi Electroacupuncture elicits dual effects: stimulation of delayed gastric emptying and inhibition of accelerated colonic transit induced by restraint stress in rats
    Masahiro Iwa
    Department of Surgery, Duke University and Durham Veterans Affairs Medical Center, Durham, North Carolina 27705, USA
    Dig Dis Sci 51:1493-500. 2006
    ..Solid gastric emptying was significantly delayed by restraint stress (29.6+/-2.4%; n=7) compared to that of controls (60.0+/-2...
  50. pmc Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual β-cell function
    Urd Kielgast
    Department of Endocrinology, Hvidovre University Hospital, Copenhagen, Denmark
    Diabetes 60:1599-607. 2011
    ....
  51. ncbi Muscarinic-dependent inhibition of gastric emptying and intestinal motility by fractions of Maytenus ilicifolia Mart ex. Reissek
    Cristiane Hatsuko Baggio
    Department of Pharmacology, Sector of Biological Sciences, Universidade Federal do Parana, Curitiba, PR, Brazil
    J Ethnopharmacol 123:385-91. 2009
    ..Maytenus ilicifolia Mart. ex. Reissek (Celastraceae) is widely used in Brazilian folk medicine to treat gastric disturbances...
  52. ncbi Effects of retrograde gastric electrical stimulation with pulse trains on gastric emptying of solids and plasma hormones in dogs
    Geng Qing Song
    Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1307 Luoyu Road, Wuhan, P R 430074, China
    Am J Surg 194:122-7. 2007
    ..The aim of this study was to investigate the effects of RGES with trains of pulses on gastric slow waves, gastric emptying of solids, and plasma concentrations of satiety-related peptides and glucose.
  53. ncbi Scintigraphic evaluation of gastric emptying in obese patients submitted to sleeve gastrectomy compared to normal subjects
    Italo Braghetto
    Department of Surgery, Hospital Clinico Universidad de Chile, Santos Dumont 999, Santiago, Chile
    Obes Surg 19:1515-21. 2009
    ..This operation could be associated with motor gastric dysfunction and abnormal gastric emptying. The purpose of this prospective study is to present the results of gastric emptying to liquids and solids ..
  54. ncbi The role of postprandial releases of insulin and incretin hormones in meal-induced satiety--effect of obesity and weight reduction
    C Verdich
    Research Department of Human Nutrition, Centre for Advanced Food Studies, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    Int J Obes Relat Metab Disord 25:1206-14. 2001
    ..Previous studies have indicated that the secretion of the intestinal satiety hormone glucagon-like peptide-1 (GLP-1) is attenuated in obese subjects...
  55. ncbi Effect of restraint and footshock stress and norepinephrine treatment on gastric emptying in rats
    Fumitake Tsukada
    Department of Radiopharmacy, Tohoku Pharmaceutical University, Aoba ku, Sendai, Japan
    Biol Pharm Bull 26:368-70. 2003
    We investigated the effects of restraint and footshock stress and norepinephrine treatment on gastric emptying. The gastric emptying was significantly inhibited by restraint stress...
  56. pmc Gastric transit and small intestinal transit time and motility assessed by a magnet tracking system
    Jonas Worsøe
    Department of Surgery P, Aarhus University Hospital, Aarhus, Denmark
    BMC Gastroenterol 11:145. 2011
    ..The aim was to test the validity of MTS-1 for assessment of gastric transit time and small intestinal transit time, and to illustrate transit patterns detected by the system...
  57. ncbi Energy homeostasis and gastric emptying in ghrelin knockout mice
    B De Smet
    Centre for Gastroenterological Research, Catholic University of Leuven, Gasthuisberg, 3000 Leuven, Belgium
    J Pharmacol Exp Ther 316:431-9. 2006
    To elucidate the role of endogenous ghrelin in the regulation of energy homeostasis and gastric emptying, ghrelin knockout mice (ghrelin(-/-)) were generated...
  58. ncbi Urocortin reduces food intake and gastric emptying in lean and ob/ob obese mice
    A Asakawa
    Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan
    Gastroenterology 116:1287-92. 1999
    b>Gastric emptying plays an important role in regulating food intake. This study was designed to investigate whether intraperitoneally injected urocortin reduces gastric emptying, feeding, and body weight in lean and ob/ob obese mice.
  59. ncbi Retrograde gastric pacing reduces food intake and delays gastric emptying in humans: a potential therapy for obesity?
    Shukun Yao
    Department of Gastroenterology, Peking Union Medical College Hospital, PUMC, Beijing, China
    Dig Dis Sci 50:1569-75. 2005
    ..of this study was to investigate the effects of retrograde gastric pacing (RGP) on food and water intake, and gastric emptying in humans...
  60. pmc Gastric emptying in hereditary transthyretin amyloidosis: the impact of autonomic neuropathy
    J Wixner
    Departments of Public Health and Clinical Medicine, Umea University, Umea, Sweden
    Neurogastroenterol Motil 24:1111-e568. 2012
    ..The aim of this study was to investigate the impact of autonomic neuropathy on gastric emptying in hereditary transthyretin amyloidosis and to relate these findings to nutritional status, GI symptoms, ..
  61. ncbi Subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) prevents postoperative delayed gastric emptying
    Hiroshi Kurahara
    Department of Surgical Oncology and Digestive Surgery, Graduate School of Medical Sciences, Kagoshima University, Japan
    J Surg Oncol 102:615-9. 2010
    Delayed gastric emptying (DGE) is one of main complications after pylorus-preserving pancreaticoduodenectomy (PPPD) with regional lymph node dissection (RLND)...
  62. ncbi Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice
    Pieter Jan Verhulst
    Centre for Gastroenterological Research, Catholic University of Leuven, Leuven, Belgium
    Gastroenterology 135:1267-76. 2008
    ..Mice with streptozotocin (STZ)-induced diabetes exhibit hyperphagia, altered gastric emptying, and increased plasma ghrelin levels...
  63. ncbi Peptide YY(3-36) inhibits gastric emptying and produces acute reductions in food intake in rhesus monkeys
    Timothy H Moran
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Ross 618, 720 Rutland Ave, Baltimore, MD 21205, USA
    Am J Physiol Regul Integr Comp Physiol 288:R384-8. 2005
    ..3-3.0 nmol/kg) to affect liquid gastric emptying and daily 6-h food intake in male rhesus monkeys...
  64. ncbi The effect of different dosages of guar gum on gastric emptying and small intestinal transit of a consumed semisolid meal
    M A van Nieuwenhoven
    Department of Gastroenterology, Maastricht University, The Netherlands
    J Am Coll Nutr 20:87-91. 2001
    There is no consensus about the effect of guar gum supplementation on gastrointestinal transit. It has been suggested that guar gum slows gastric emptying and intestinal transit, thus inducing an increased feeling of satiety.
  65. ncbi Cholecystokinin
    Graham J Dockray
    Physiological Laboratory, Institute of Translational Medicine, University of Liverpool, Liverpool, UK
    Curr Opin Endocrinol Diabetes Obes 19:8-12. 2012
    Cholecystokinin (CCK) controls nutrient delivery to the small intestine by inhibiting food intake and gastric emptying. This review deals with recent work shedding new light on how and when.
  66. ncbi The dorsal vagal complex as a site for cocaine- and amphetamine-regulated transcript peptide to suppress gastric emptying
    Ulrika Smedh
    Department of Psychiatry and Behavioural Science, John Hopkins University School of Medecine, Baltimore, Maryland, USA
    Am J Physiol Regul Integr Comp Physiol 291:R124-30. 2006
    ..We hypothesized that dorsal hindbrain effects of CARTp on gastric emptying are mediated by the vagus nerve and that the dorsal vagal complex (DVC) is a site of action for the gastric ..
  67. ncbi Gastric emptying and intragastric distribution of a solid meal in functional dyspepsia: influence of gender and anxiety
    Sônia Letícia Silva Lorena
    Disciplina de Gastroenterologia, Departamento de Clinica Medica, Universidade Estadual de Campinas, Sao Paulo, Brazil
    J Clin Gastroenterol 38:230-6. 2004
    ..Gastric dysmotility and psychological factors have been implicated in the pathophysiology of functional dyspepsia...
  68. ncbi Gastric emptying of a carbohydrate-electrolyte drink during a soccer match
    J B Leiper
    Department of Biomedical Sciences, University Medical School, Foresterhill, Aberdeen AB25 2ZD, UK
    Med Sci Sports Exerc 33:1932-8. 2001
    To investigate the effect on gastric emptying of intermittent exercise at varying intensities such as occurs during a soccer match.
  69. pmc Low-dose erythromycin reduces delayed gastric emptying and improves gastric motility after Billroth I pylorus-preserving pancreaticoduodenectomy
    S Ohwada
    Second Department of Surgery, Gunma University Faculty of Medicine, Maebashi, Japan
    Ann Surg 234:668-74. 2001
    To test the hypothesis that early and low doses of erythromycin reduce the incidence of early delayed gastric emptying (DGE) and induce phase 3 of the migratory motor complex in the stomach after Billroth I pylorus-preserving ..
  70. ncbi Delay in gastric emptying in patients with chronic renal failure
    H Strid
    Dept of Internal Medicine, Sahlgrenska University Hosptial, Goteborg, Sweden
    Scand J Gastroenterol 39:516-20. 2004
    Gastrointestinal (GI) symptoms are common in patients with chronic renal failure (CRF). Delayed gastric emptying might be a possible pathophysiological mechanism...
  71. pmc Effect of cinnamon on gastric emptying, arterial stiffness, postprandial lipemia, glycemia, and appetite responses to high-fat breakfast
    Oonagh Markey
    Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland
    Cardiovasc Diabetol 10:78. 2011
    Cinnamon has been shown to delay gastric emptying of a high-carbohydrate meal and reduce postprandial glycemia in healthy adults...
  72. ncbi Gastric emptying: the validity of the paracetamol absorption test adjusted for individual pharmacokinetics
    A W Medhus
    Department of Medicine, Ulleval University Hospital, Oslo, Norway
    Neurogastroenterol Motil 13:179-85. 2001
    An algorithm for the paracetamol absorption test for gastric emptying, adjusting for individual pharmacokinetics, was recently developed. The aim of the present study was to validate the use of this algorithm...
  73. ncbi Effect of distal subtotal gastrectomy with preservation of the celiac branch of the vagus nerve to gastrointestinal function: an experimental study in conscious dogs
    Hiroyuki Ando
    Department of General Surgical Science and the 21st Century COE Program, Gunma University Graduate School of Medicine 3 39 22, Japan
    Ann Surg 247:976-86. 2008
    ..To evaluate the effects of distal subtotal gastrectomy with preservation of the celiac branch of the vagus nerve on gastrointestinal function...
  74. ncbi Paradoxical impact of body positioning on gastroesophageal reflux and gastric emptying in the premature neonate
    Taher I Omari
    Department of Paediatrics, University of Adelaide, Center for Paediatric and Adolescent Gastroenterology, Neonatal Medicine Unit, Women s and Children s Hospital, North Adelaide Australia
    J Pediatr 145:194-200. 2004
    To combine manometry and impedance to characterize the mechanisms of gastroesophageal reflux (GER) and to explore their relation to the rate of gastric emptying (GE) and body position.
  75. ncbi Association of the predominant symptom with clinical characteristics and pathophysiological mechanisms in functional dyspepsia
    George Karamanolis
    Center for Gastroenterological Research, University Hospital Gasthuisberg, Leuven, Belgium
    Gastroenterology 130:296-303. 2006
    ..The aim of this study was to analyze the relationship of predominant pain or discomfort with pathophysiological mechanisms and to evaluate whether considering individual predominant symptoms yields better results...
  76. ncbi Incidence of pancreatic anastomotic failure and delayed gastric emptying after pancreatoduodenectomy in 507 consecutive patients: use of a web-based calculator to improve homogeneity of definition
    Yasushi Hashimoto
    Section of General, Vascular, and Thoracic Surgery, Virginia Mason Medical Center, Seattle, WA 98111, USA
    Surgery 147:503-15. 2010
    Many definitions are used in the literature for pancreatic anastomotic failure (PAF) and delayed gastric emptying (DGE) after pancreatoduodenectomy (PD)...
  77. ncbi Effects of rikkunshi-to, a traditional Japanese medicine, on the delay of gastric emptying induced by N(G)-nitro-L-arginine
    Toshitaka Kido
    Department of Medicinal Informatics, Graduate School of Medicine, Kanazawa University, Japan
    J Pharmacol Sci 98:161-7. 2005
    We evaluated the effects of Rikkunshi-to and several of its ingredients on the delay of gastric emptying induced by a nitric oxide (NO) synthase inhibitor, N(G)-nitro-L-arginine (L-NNA)...
  78. ncbi Gastric emptying before and after liver transplantation for familial amyloidotic polyneuropathy, Portuguese type (Val30Met)
    Ole B Suhr
    Department of Medicine, Umea University Hospital, SE 901 85 Umea, Sweden
    Amyloid 10:121-6. 2003
    ..the frequency of gastric retention in FAP patients and to evaluate the impact liver transplantation has on gastric emptying. Twenty-two patients, who had undergone liver transplantation, and had been re-examined for gastric retention ..
  79. pmc Acupuncture in critically ill patients improves delayed gastric emptying: a randomized controlled trial
    Florian Pfab
    Department of Anesthesiology, University Hospital Regensburg, Regensburg, Germany
    Anesth Analg 112:150-5. 2011
    ..patient outcomes in the intensive care unit (ICU), tubefeed administration is often complicated by delayed gastric emptying and gastroesophageal reflux...
  80. ncbi Inhibition of gastric emptying by acarbose is correlated with GLP-1 response and accompanied by CCK release
    F Y Enç
    Division of Gastroenterology, Department of Internal Medicine, University of Marmara Medical School, Istanbul 81326
    Am J Physiol Gastrointest Liver Physiol 281:G752-63. 2001
    We investigated the effect of acarbose, an alpha-glucosidase and pancreatic alpha-amylase inhibitor, on gastric emptying of solid meals of varying nutrient composition and plasma responses of gut hormones...
  81. pmc Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats
    A Stengel
    CURE Digestive Diseases Research Center, Center for Neurobiology of Stress, Department of Medicine, Digestive Diseases Division at the University of California Los Angeles, and VA Greater Los Angeles Health Care System, Los Angeles, CA 90073, USA
    Neurogastroenterol Motil 23:e294-308. 2011
    ..Brain CRF signaling is involved in delaying gastric emptying (GE) immediately post surgery...
  82. ncbi Ghrelin accelerates gastric emptying via early manifestation of antro-pyloric coordination in conscious rats
    Hajime Ariga
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Regul Pept 146:112-6. 2008
    Ghrelin is known to enhance gastric motility and accelerate gastric emptying of liquid and solid food in rats...
  83. ncbi The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesity
    A Flint
    Research Department of Human Nutrition, Center for Food Research, The Royal Veterinary and Agricultural University, Rolighedsvej 30, DK 1958 Frederiksberg C, Denmark
    Int J Obes Relat Metab Disord 25:781-92. 2001
    ..The objective of this study was to investigate the effects of a GLP-1 infusion in a physiological dose on appetite sensations, energy intake, gastric emptying, energy and substrate metabolism.
  84. ncbi Interactions between gastric emptying and satiety, with special reference to glucagon-like peptide-1
    P M Hellstrom
    Department of Internal Medicine, Unit of Gastroenterology Karolinska Hospital, Karolinska Institutet, SE 171 76, Stockholm, Sweden
    Physiol Behav 74:735-41. 2001
    The slowing of gastric emptying is an important mechanism for the satiating effect of gut peptide signaling...
  85. ncbi Risk factors of pancreatic fistula and delayed gastric emptying after pancreaticoduodenectomy with pancreaticogastrostomy
    Emilie Lermite
    Department of Digestive Surgery, University Hospital, Angers, France
    J Am Coll Surg 204:588-96. 2007
    Pancreatic fistula (PF) and delayed gastric emptying (DGE) are, respectively, the most frightening and most frequent complications after pancreaticoduodenectomy (PD)...
  86. pmc The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet
    V Di Marzo
    Endocannabinoid Research Group, Institute of Biomolecular Chemistry, National Research Council, Pozzuoli, Naples, Italy
    Br J Pharmacol 153:1272-80. 2008
    ..However, their role in the regulation of gastric emptying is largely unexplored...
  87. ncbi Gastric emptying of a non-digestible solid: assessment with simultaneous SmartPill pH and pressure capsule, antroduodenal manometry, gastric emptying scintigraphy
    D Cassilly
    Gastroenterology Section, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Neurogastroenterol Motil 20:311-9. 2008
    b>Gastric emptying of digestible solids occurs after trituration of food particles. Non-digestible solids are thought to empty with phase III of the migrating motor complex (MMC)...
  88. ncbi Ob/ob mice as a model of delayed gastric emptying
    Akihiro Asakawa
    Department of Clinical Molecular Medicine, Division of Diabetes, Digestive and Kidney Diseases, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Japan
    J Diabetes Complications 17:27-8. 2003
    Diabetic gastroparesis is a well-recognized delay of gastric emptying in diabetic patients. We assessed the gastric emptying rate in ob/ob mice, a genetic model of obesity and diabetes...
  89. ncbi Acotiamide hydrochloride (Z-338), a novel prokinetic agent, restores delayed gastric emptying and feeding inhibition induced by restraint stress in rats
    K Seto
    Central Research Laboratories, Zeria Pharmaceutical Co Ltd, Saitama, Japan
    Neurogastroenterol Motil 20:1051-9. 2008
    ..Therefore, effects of acotiamide on stress-related symptoms, delayed gastric emptying and feeding inhibition, in rats were examined...
  90. ncbi Pharmacological effects of oxytocin on gastric emptying and intestinal transit of a non-nutritive liquid meal in female rats
    Chiu Lung Wu
    Department of Physiology, School of Medicine, National Yang Ming University, Shih Pai, Taipei 11221, Taiwan, Republic of China
    Naunyn Schmiedebergs Arch Pharmacol 367:406-13. 2003
    The effects of oxytocin (OT) on gastric emptying, gastrointestinal transit, and plasma levels of cholecystokinin (CCK) were studied in female rats...
  91. ncbi Cholecystokinin affects gastric emptying and stomach motility in the rainbow trout Oncorhynchus mykiss
    C Olsson
    Department of Zoophysiology, University of Goteborg, Box 463, S 405 30 Goteborg, Sweden and Department of Radiation Physics, Sahlgrenska Hospital, Goteborg, Sweden
    J Exp Biol 202:161-70. 1999
    In this study, we describe new methods for recording gastric emptying and in vivo measurements of intragastric pressure in fish...
  92. ncbi Role of gastric sensorimotor dysfunction in gastrointestinal symptoms and energy intake in liver cirrhosis
    Evangelos Kalaitzakis
    Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    Scand J Gastroenterol 42:237-46. 2007
    ..The aim of this study was to investigate gastric accommodation to a meal and sensitivity to gastric distension with reference to energy intake, nutritional status and gastrointestinal symptoms in liver cirrhosis...
  93. ncbi Functional dyspepsia: mechanisms of symptom generation and appropriate management of patients
    Michael Camilleri
    Clinical Enteric Neuroscience Translational and Epidemiological Research Group, Mayo Clinic College of Medicine, Charlton 8 110, 200 First Street, SW, Rochester, MN 55905, USA
    Gastroenterol Clin North Am 36:649-64, xi-x. 2007
    ..To achieve greater therapeutic efficacy, it may be necessary to target the therapeutic approach to a specific pathophysiology, such as impaired gastric emptying.
  94. ncbi Comparison of gastric emptying of a nondigestible capsule to a radio-labelled meal in healthy and gastroparetic subjects
    B Kuo
    Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Aliment Pharmacol Ther 27:186-96. 2008
    b>Gastric emptying scintigraphy (GES) using a radio-labelled meal is used to measure gastric emptying...
  95. pmc Delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: validation of International Study Group of Pancreatic Surgery classification and analysis of risk factors
    Giuseppe Malleo
    Department of Surgery, General Surgery B Unit, G B Rossi Hospital, University of Verona, Verona, Italy
    HPB (Oxford) 12:610-8. 2010
    This study evaluates the incidence and clinical features and associated risk factors of delayed gastric emptying (DGE) after pancreaticoduodenectomy, employing the International Study Group of Pancreatic Surgery (ISGPS) consensus ..
  96. ncbi Evaluation of gastric emptying measured with the 13C-octanoic acid breath test in patients with functional dyspepsia: comparison with ultrasonography
    S Aoki
    First Dept of Intestinal Medicine, Hiroshima University School of Medicine, Japan
    Scand J Gastroenterol 37:662-6. 2002
    As a non-invasive modality by which to evaluate the gastric emptying of a solid meal, the 13C-octanoic acid breath test has recently become more widely used...
  97. ncbi Effect of inhibition of inducible nitric oxide synthase and guanylyl cyclase on endotoxin-induced delay in gastric emptying and intestinal transit in mice
    Benedicte Y De Winter
    Division of Gastroenterology, Faculty of Medical and Pharmaceutical Sciences, University of Antwerp, Belgium
    Shock 18:125-31. 2002
    ..After 18 h, general well being deteriorated and the mice developed hypothermia and a significant delay in gastric emptying and intestinal transit as measured by Evans blue...
  98. ncbi Muscarinic blockade inhibits gastric emptying of mixed-nutrient meal: effects of weight and gender
    K L Teff
    Monell Chemical Senses Center, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Physiol 276:R707-14. 1999
    We compared the vagal contribution to gastric emptying in lean and obese subjects by monitoring gastric emptying of a meal during muscarinic blockade...
  99. ncbi Effect of muesli with 4 g oat beta-glucan on postprandial blood glucose, gastric emptying and satiety in healthy subjects: a randomized crossover trial
    Joanna Hlebowicz
    Department of Medicine, Malmo University Hospital, University of Lund, Malmo, Sweden
    J Am Coll Nutr 27:470-5. 2008
    ..The aim of this study was to evaluate the effect of an extruded muesli product based on oat beta-glucan on the rate of gastric emptying, postprandial blood glucose and satiety in healthy subjects.
  100. ncbi Rabeprazole delays gastric emptying of a nutrient liquid
    Masaki Sanaka
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    J Gastroenterol Hepatol 22:1806-9. 2007
    It is generally considered that gastric acid suppression delays gastric emptying of solid meals because gastric hypoacidity impairs peptic digestion and antral triturition. Rabeprazole is one of the most potent acid suppressants...
  101. ncbi Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2
    L Wang
    Center for Ulcer Research and Education, Veterans Affairs Greater Los Angeles Healthcare System, Department of Medicine, Division of Digestive Diseases and Brain Research Institute, University of California at Los Angeles, Los Angeles 90073, USA
    Am J Physiol Regul Integr Comp Physiol 281:R1401-10. 2001
    Intraperitoneal urocortin inhibits gastric emptying and food intake in mice. We investigated corticotropin-releasing factor receptor (CRF-R) subtypes involved in intraperitoneal urocortin actions using selective CRF-R antagonists...

Research Grants65

  1. Dual-pulse electrical stimulation for gastroparesis
    Jiande Chen; Fiscal Year: 2004
    ..It is hypothesized that GES with such a stimulus improves both gastric emptying (via long pulses) and symptoms of gastroparesis (via short pulses)...
  2. A MULTI-CHANNEL GASTRIC PACER FOR TREATING GASTROPARESIS
    Robert Ross; Fiscal Year: 2004
    In a new therapeutic approach for delayed gastric emptying and gastroparesis, Virginia Technologies, Inc...
  3. Nitric Oxide and gastric motility in female diabetics
    Pandu R Gangula; Fiscal Year: 2010
    ..Our preliminary data suggests that a significant impairment of nitrergic relaxation and delayed gastric emptying for solids was demonstrated selectively in females after diabetes induction with streptozotocin (STZ)...
  4. The effects of glucose on central vagal brainstem circuits
    KIRSTEEN NAIRN BROWNING; Fiscal Year: 2013
    ..By decreasing gastric tone and motility, the receptive relaxation reflex delays gastric emptying, slows the rate at which chyme is transported to the intestine and, by consequence, regulates the rate of ..
  5. Sweet taste receptors and glucose metabolism in healthy and T2DM humans
    Karen L Teff; Fiscal Year: 2012
    ..interest as GLP plays a critical role in glucose homeostasis by stimulating insulin release, delaying gastric emptying and inhibiting hepatic glucose production...
  6. Physiological Role of CNS GLP-2 Receptor in Energy Homeostasis
    Xinfu Guan; Fiscal Year: 2010
    ..crypt cell proliferation and mucosal blood flow to promote nutrient absorption, while it also decreases gastric emptying and gut motility to inhibit food intake...
  7. Pharmacogenomics of Gastric Function &Weight in Obesity
    MICHAEL L CAMILLERI; Fiscal Year: 2013
    ..research proposal seeks to further examine the association of candidate genes with stomach functions (rate of gastric emptying, gastric volume and maximum tolerated volume as a marker of sensitivity) that are associated with fullness ..
  8. Role of Parabrachial Nucleus Neuropeptides in Feeding
    John Paul Baird; Fiscal Year: 2011
    ..such as obesity, anorexia, bulimia, failure to thrive, gastric reflux, cachexia, early satiety, delayed gastric emptying, dysgeusia, and anosmia contribute to diseases including hypertension, stroke, diabetes, and heart disease, ..
  9. Receptor Regulation of CCK Cell Function
    Rodger A Liddle; Fiscal Year: 2013
    ..Specifically CCK regulates gallbladder contraction, pancreatic enzyme secretion, delays gastric emptying, and induces satiety...
  10. Developmental Origins of Functional Dyspepsia
    Sushil K Sarna; Fiscal Year: 2013
    ..of Functional Dyspepsia are upper abdominal pain that is exaggerated by ingestion of a meal, and delayed gastric emptying. The etiology of these symptoms is not known, which has hampered efforts to develop effective therapeutic ..
  11. GASTROINTESTINAL INTEGRATION AND FEEDING
    Timothy H Moran; Fiscal Year: 2013
    ..nonhuman primate model that has been successful in elucidating feedback controls on food intake and gastric emptying that have direct relevance to man...
  12. Antidepressant Therapy for Functional Dyspepsia
    YURI ANN SAITO LOFTUS; Fiscal Year: 2011
    ..2) Acceleration of solid gastric emptying, reduction of postprandial satiation and enhanced gastric volume change with a meal on antidepressant therapy ..
  13. Role of Renal Dipeptidyl Peptidase IV
    EDWIN KERRY JACKSON; Fiscal Year: 2013
    ..thereby exert antidiabetic actions by increasing insulin release, inhibiting glucagon secretion and retarding gastric emptying. However, DPPIV metabolizes at least 35 endogenous substrates, and the pharmacological consequences of ..
  14. Automated Intestinal Electrical Stimulation for Diabetes
    Jiande Chen; Fiscal Year: 2013
    ..the hypothesis that IES-induced reduction in postprandial blood glucose is mediated mechanically by delayed gastric emptying and accelerated intestinal transit, and hormonally by reduced ghrelin and increased release of GLP-1...
  15. Mechanisms Regulating Gastrointestinal Hormone Secretion
    Rodger A Liddle; Fiscal Year: 2013
    ..gastrointestinal hormone that regulates gallbladder contraction, pancreatic enzyme secretion, delays gastric emptying, and induces satiety...
  16. Type A CCK Receptor Structure, Function &Regulation
    Laurence J Miller; Fiscal Year: 2013
    ..including the stimulation of pancreatic exocrine secretion and gallbladder emptying, the regulation of gastric emptying and bowel transit, and the modification of appetite...
  17. Effects of hyperglycemia on gastric emptying
    Toku Takahashi; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Abstract Gastroparesis (delayed gastric emptying) occurs in the absence of mechanical obstruction. Although associated with many diseases, the most frequent cause of gastroparesis is diabetes...
  18. Advancing Science for the Diagnosis and Treatment of Gastroparesis
    Pankaj J Pasricha; Fiscal Year: 2013
    ..DESCRIPTION (provided by applicant): Gastroparesis is a disorder of gastric function characterized by delay in gastric emptying, frequently associated with chronic nausea and vomiting, early satiety, postprandial fullness, abdominal pain,..
  19. Gastric dysreflexia after spinal cord injury
    Gregory M Holmes; Fiscal Year: 2013
    ..In the present proposal we will use an animal model of T3-SCI combined with in vivo physiological (gastric emptying or motility and vagus nerve) recording, and molecular (RT-PCR and ELISA) approaches with the aim of defining ..
  20. Continuation of the NIDDK Gastroparesis Consortium
    Irene Sarosiek; Fiscal Year: 2013
    ..by applicant): Gastroparesis (GP) is a disorder of gastric motilityfunction characterized by a delay in gastric emptying, frequently associated with chronic nausea and vomiting, early satiety, postprandial fullness, abdominal pain,..
  21. Integrated approaches to close the loop in type 1 diabetes
    Yogish C Kudva; Fiscal Year: 2013
    ..2) We will explore if gastric emptying rate can predict post prandial meal glucose appearance, insulin action and 24 hour glucose variability in ..
  22. Transcutaneous electroacupuncture for gastroparesis
    Jiande Chen; Fiscal Year: 2010
    ..Improvement has been observed with EA or TEA in gastric emptying as well as dyspeptic symptoms...
  23. Novel Glucagon Modulators and the Closed Loop System
    Rubina A Heptulla; Fiscal Year: 2012
    ..in the postprandial period reduces immediate postprandial hyperglycemia by suppressing glucagon and delaying gastric emptying. The hormone GLP-1 has similar actions to amylin and may also be beneficial in T1DM...
  24. ORAL DRUG DELIVERY AND BIOAVAILABILITY--AIDS
    Gordon Amidon; Fiscal Year: 1993
    ..intersubject variation based on the measured variation of the underlying physiological parameters, such as gastric emptying rate, intestinal transit rate, intestinal pH and permeability, in both the fasted and fed-states...
  25. Feeding and Pancreatic Rest in Acute Pancreatitis
    DAVID CLEMENT WHITCOMB; Fiscal Year: 2012
    ..with the same dietary formula and does not increase the risk of aspiration despite the known impairmrnt of gastric emptying. This led to the recommendation that NG feeding should be used preferentially as it does not require ..
  26. Gastroparesis Clinical Research Consortium-University of Michigan Clinical Center
    William L Hasler; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Gastroparesis is characterized by delayed gastric emptying in association with nausea, vomiting, fullness, early satiety, and pain that has devastating impacts on quality of life...
  27. Physiologic Effects of High-Dose Gastric Antral Botulinum Toxin Injections
    Mark D Topazian; Fiscal Year: 2010
    ..Delayed gastric emptying occurred in the group that received 300 U BTA. Body weight loss (mean -4...
  28. Pathobiology of the Enteric System
    Joseph H Szurszewski; Fiscal Year: 2013
    Disorders of gastric emptying in patients with diabetes, eating disorders and in idiopathic conditions are a significant cause of morbidity. Current approaches for effectively managing gastric emptying disorders are ineffective...
  29. Reduction of Dietary Oxalate
    Qingshan Li; Fiscal Year: 2013
    ..with cell walls, and capable to degrade most available ingested oxalate in the human stomach within the gastric emptying time. Captozyme was successful at finding two enzymes with more than ideal properties...
  30. NEUROENDOCRINE ETIOLOGY OF DIABETIC GASTROPATHY
    Thomas Nowak; Fiscal Year: 1999
    ..The aim of this research proposal is to study the neural and endocrine controls of gastric emptying in experimental diabetes...
  31. Effects of Acupuncture on Gastric Motility in Rats
    Toku Takahashi; Fiscal Year: 2004
    ..study demonstrated that acupuncture to the hind limb potentiates gastric contractions and accelerates solid gastric emptying in conscious rats...
  32. CHOLECYSTOKININ--ROLE IN POSTPRANDIAL GASTRIC MOTILITY
    Helen Raybould; Fiscal Year: 1993
    ..Changes in gastroduodenal motility and gastric emptying in response to duodenal perfusion with protein, soya bean trypsin inhibitor, acid and glucose and duodenal ..
  33. EFFECT OF GINSENG ON CISPLATIN-INDUCED EMESIS
    Chun Su Yuan; Fiscal Year: 2006
    ..Cisplatin-induced delayed gastric emptying could also contribute to the pathogenesis of nausea/vomiting...
  34. MOTILITY OF THE DIGESTIVE TRACT IN HEALTH AND DISEASE
    KEITH KELLY; Fiscal Year: 1993
    ..whether distention of a canine ileal puch will release neurotensin and enteroglucagon, slow the rate of gastric emptying and intestinal transit and enhance intestinal absorption of liquids and solids after ileal pouch-anal ..
  35. Reduction of Dietary Oxalate
    Qingshan Li; Fiscal Year: 2010
    ..with cell walls, and capable to degrade most available ingested oxalate in the human stomach within the gastric emptying time. This product will ideally be taken with meals and oxalate containing snacks...
  36. BIOSYNTHESIS OF GASTROINTESTINAL HORMONES
    Andrew Leiter; Fiscal Year: 1990
    ..Other effects of PYY include inhibition of intestinal motility, gastric emptying, and gastric secretion of pepsin as well as reduction of intestinal blood flow...
  37. Dual Pulse Electrical Stimulation for Gastroparesis
    Jiande Chen; Fiscal Year: 2007
    ..fundic relaxation, visceral hypersensitivity, gastric dysrhythmia, gastric antral hypomotility, and delayed gastric emptying. The electrical stimulus is composed of long pulses (which will normalize dysrhythmia and enhance fundic ..
  38. Function of Nkx homeobox genes in enteroendocrine cell differentiation
    TRACY EDIGER; Fiscal Year: 2009
    ..gut epithelium comprise the largest endocrine organ in the body and serve vital physiologic functions such as gastric emptying and motility, pancreatic and biliary secretion, and growth and repair of gut epithelium...
  39. Continuation: UMMC's Clinical Center in NIDDK's Gastroparesis Research
    THOMAS LYMAN ABELL; Fiscal Year: 2013
    ..can reduce Gl symptoms by at least 50% for individual patients, to assess the impact of temporary GES on gastric emptying times, EGG values, neuro-hormonal and autonomic status markers, and HRQOL measures, and to evaluate EGG ..
  40. DUODENOGASTRIC REFLUX IN HEALTH AND DISEASE
    Ronald Hinder; Fiscal Year: 1991
    ..The pH environment is probably influenced by eating, changes in posture, DGR, gastric emptying and acid secretion, therefore the intraluminal pH environment will be mapped at different sites in the ..
  41. ETHANOL MODULATION OF ENTERIC NEUROTRANSMISSION
    Terence Smith; Fiscal Year: 2000
    ..GI) tract are particularly common, including decreased esophageal peristalsis, esophageal reflux, abnormal gastric emptying, hyperactive bowel and diarrhea...
  42. Novel Evaluation & Treatment of Gastric Dysmotility
    HENRY PAUL PARKMAN; Fiscal Year: 2010
    ..These include electrogastrography, a scintigraphic test to simultaneously assess gastric emptying and volume, and a capsule that records both pH and pressure to provide an assessment of gastric residence ..
  43. Intermedin / AM2 in Human Pregnancy
    MADHU LATA CHAUHAN; Fiscal Year: 2009
    ..to lower blood pressure in normal and hypertensive rats, exhibits cardioprotective effects and suppress gastric emptying and food intake and is regulated by estrogen...
  44. ADAPTIVE ELECTRIC CURRENT COMPUTED TOMOGRAPHY SYSTEM
    JONATHAN NEWELL; Fiscal Year: 1990
    ..Gastric secretion and gastric emptying are of interest in several pathological states, and preliminary studies suggest the use of impedance ..
  45. SPINAL & BRAIN MODULATION OF GASTROINTESTINAL MOTILITY
    Frank Porreca; Fiscal Year: 1992
    ..The endpoints to be studied are all standard in our laboratory and include determination of gastric emptying and small and large bowel transit, stomach and intestinal intraluminal pressure in the rat as will as GI ..
  46. UPPER GI TRACT MEDIATION OF THE SATIETY EFFECTS OF FATS
    James Gibbs; Fiscal Year: 1999
    ..This will be accomplished by: (1) Determining the gastric emptying rates and the compositions of the various lipid moieties that enter the intestine when fats of different ..
  47. TOPICAL DRUG DELIVERY FOR GASTRIC H. PYLORI INFECTION
    Catherine Woods; Fiscal Year: 2000
    ..profile, the degree of gelation, gelation temperature, and effect of excipients will be correlated with gastric emptying times in human volunteers as determined by scintography...
  48. ELECTRICAL CONTROL OF GASTRODUODENAL MOTILITY
    KENTON SANDERS; Fiscal Year: 2003
    b>Gastric emptying is regulated by pressures and resistances across the gastroduodenal junction (GDJ). These factors are produced by the muscular activities of the stomach, pyloric sphincter and proximal small intestine...
  49. NON-INVASIVE BREATH TEST FOR MEASURING GASTRIC EMPTYING
    KEITH GOODMAN; Fiscal Year: 2000
    ..The test will be used to identify patients with gastroparesis (impaired gastric emptying) and monitor the effectiveness of their treatment...
  50. Novel direct vago-vagal recording of i.v. ghrelin action
    David Adelson; Fiscal Year: 2007
    ..Increased circulating levels of ghrelin are associated with increased hunger, food intake, and gastric emptying. This latter function is of interest due to the clinical importance of postoperative gastric ileus and the ..
  51. Treatment of diabetic gastroparesis with nitric oxide
    Robert Raulli; Fiscal Year: 2007
    ..a currently used but problematic treatment), and a study of how NO affects the physiological mechanisms of gastric emptying. Successful completion of the specific aims of the proposal will definitively determine the feasibility of ..
  52. THERAPEUTIC POTENTIAL OF INTESTINAL PACING FOR OBESITY
    Jiande Chen; Fiscal Year: 2003
    ..aims are: 1) to study the effect of intestinal electrical stimulation on gastric tone/contractions as well as gastric emptying and to derive the most effective stimulation method that inhibits gastric motility; 2) to investigate the ..
  53. ELECTRICAL STIMULATION FOR TREATMENT OF GASTROPARESIS
    Jiande Chen; Fiscal Year: 1999
    ..The second sets of experiments will be performed to investigate the effect of the proposed method on gastric emptying. Delayed gastric emptying of liquid and solid in dogs will be induced using duodenal distension and clonidine,..
  54. Treatment of Gastroparesis with Multi-Channel Pacing
    Zhiyue Lin; Fiscal Year: 2005
    ..It is hypothesized that MGS will result in accelerated gastric emptying of solids and improved symptoms of gastroparesis and quality of life...
  55. EFFECT OF ALCOHOL ON GASTRIC MOTOR FUNCTION
    LINDA KNIGHT; Fiscal Year: 1991
    ..It has not been shown, however, how the electrical/mechanical activity of gastric muscle ex vivo relates to gastric emptying in vivo...
  56. GASTRIC MOTILITY IN THE NEWBORN
    James Ryan; Fiscal Year: 1991
    ..Furthermore, it is not known how (or if) the postnatal changes in contractility affect gastric emptying. Therefore, the purpose of this study is to: 1) define the biochemical, contractile, and electrical ..
  57. WASTING IN AIDS--ROLE OF MONOKINES
    Bruce Bistrian; Fiscal Year: 1993
    ..whole body and individual tissue protein kinetics, fat and glucose metabolism, and, most recently, gastric emptying. We have also shown that some of these changes (fever and leucine oxidation in response to IL-1, shock and ..
  58. ORAL, GASTRIC AND POSTGASTRIC CONTRIBUTIONS TO SATIETY
    Joel Kaplan; Fiscal Year: 2005
    ..Analysis of gastric emptying is central to this research program insofar as emptying determines the proportion of the ingested load that ..
  59. Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory Functions
    MICHAEL L CAMILLERI; Fiscal Year: 2010
    ..These actions may be relevant to develop new treatments for IBS. The studies will also provide further understanding of the potential of medications like medical marijuana on stomach function that may be relevant to appetite control. ..
  60. ALPHA 2 ADRENERGIC CONTROL IN IRRITABLE BOWEL SYNDROME
    Michael Camilleri; Fiscal Year: 2008
    ..Significance: This project will characterize pharmacogenetic mechanisms determining the response to clonidine through studies of candidate genes that control alpha2-adrenoreceptor function and norepinephrine transport in IBS. ..
  61. ALPHA-2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBS
    Michael Camilleri; Fiscal Year: 2007
    ..abstract_text> ..
  62. POSTNATAL DEVELOPMENT OF HOMEOSTATIC NEURAL CONTROLS
    Linda Rinaman; Fiscal Year: 1999
    ..use physiological and behavioral methods to analyze the ontogeny of "dehydration anorexia" and inhibition of gastric emptying following stimulation of osmoreceptors in the basal forebrain that communicate through oxytocinergic ..
  63. NEUROTENSIN AND ENTEROHEPATIC BILE ACID REGULATION
    Robert Carraway; Fiscal Year: 1999
    ..from the applicant's abstract): Neurotensin (NT), released from the intestine by ingestion of fat, slows gastric emptying, stimulates pancreatic secretion, and enhances the uptake of fatty acids...
  64. REGULATION OF FOOD INTAKE--BRAIN AND GUT MEDIATORS
    Theodore Pappas; Fiscal Year: 1993
    ..4. Determine whether there is a relationship between the central effect of CCK/NPY on feeding and gastric emptying. 5...
  65. RAPID PORTABLE DETECTION OF DELAYED GASTRIC EMPTYING
    Hansen Mansy; Fiscal Year: 1999
    The proposed research is to develop an innovative technology for the rapid diagnosis of delayed gastric emptying. The new technology is expected to overcome limitations of the current methods which may include radiation exposure, accuracy,..