deglutition

Summary

Top Publications

  1. ncbi Acoustic signature of the normal swallow: characterization by age, gender, and bolus volume
    Julie A Y Cichero
    Department of Speech Pathology and Audiology, University of Queensland, Brisbane, Australia
    Ann Otol Rhinol Laryngol 111:623-32. 2002
  2. ncbi The effects of lingual exercise on swallowing in older adults
    Joanne Robbins
    Department of Medicine, University of Wisconsin Madison, Madison, Wisconsin, USA
    J Am Geriatr Soc 53:1483-9. 2005
  3. ncbi Electrical stimulation for swallowing disorders caused by stroke
    M L Freed
    Respiratory Care Department, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland OH 44106, USA
    Respir Care 46:466-74. 2001
  4. ncbi Reduced tongue pressure against the hard palate on the paralyzed side during swallowing predicts Dysphagia in patients with acute stroke
    Nobuko Hirota
    Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
    Stroke 41:2982-4. 2010
  5. ncbi Interrelationship of oral health status, swallowing function, nutritional status, and cognitive ability with activities of daily living in Japanese elderly people receiving home care services due to physical disabilities
    Michiko Furuta
    Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka, Japan
    Community Dent Oral Epidemiol 41:173-81. 2013
  6. ncbi An acoustic profile of normal swallowing
    Scott R Youmans
    Department of Communication Sciences and Disorders, Long Island University, Brooklyn Campus, 1 University Plaza, Brooklyn, NY 11201, USA
    Dysphagia 20:195-209. 2005
  7. ncbi Dysphagia following chemoradiation for locally advanced head and neck cancer
    N P Nguyen
    Radiation Oncology, VA North Texas Health Care System, Dallas 75216, USA
    Ann Oncol 15:383-8. 2004
  8. ncbi Oral and oropharyngeal perceptions of fluid viscosity across the age span
    Christina H Smith
    Department of Human Communication Science, University College London, London, England
    Dysphagia 21:209-17. 2006
  9. pmc Temporal variability in the deglutition literature
    Sonja M Molfenter
    Swallowing Rehabilitation Research Laboratory, Toronto Rehabilitation Institute, University Health Network, 550 University Avenue, Toronto, ON, Canada
    Dysphagia 27:162-77. 2012
  10. ncbi Real time balanced turbo field echo Cine-MRI in the analysis of deglutition events and transit times
    S Karacay
    Department of Orthodontics, Dental Sciences Center, Gulhane, Military Medical Academy, Ankara, Turkey
    J Oral Rehabil 33:646-53. 2006

Research Grants

  1. COORDINATION OF RESPIRATION AND DEGLUTITION
    ADRIENNE PERLMAN; Fiscal Year: 2003
  2. Lingual and Laryngeal Muscle Plasticity
    NADINE PATTAKOS CONNOR; Fiscal Year: 2013
  3. CHD1, Chromatin Dynamics, and Salivary Gland Differentiation
    JOSEPH ADAM HALL; Fiscal Year: 2010
  4. Manual Control of the Upper Esophageal Sphincter
    Peter Belafsky; Fiscal Year: 2013
  5. Effects of Aging on Anticipatory Functional Synergies Activated in Deglutition
    SAMANTHA EVE SHUNE; Fiscal Year: 2013
  6. Exercise as a Treatment for Tongue Weakness
    NADINE PATTAKOS CONNOR; Fiscal Year: 2013
  7. Neuromuscular control of the human tongue
    E Fiona Bailey; Fiscal Year: 2013
  8. RESPIRATORY SYSTEM INTEGRATION BY THE BRAINSTEM
    ALBERT BERGER; Fiscal Year: 2002
  9. PROLINE-RICH GLYCOPROTEIN MASTICATORY LUBRICATION
    Lawrence Tabak; Fiscal Year: 1991
  10. Lingual Mechanical Function During Swallowing
    Richard Gilbert; Fiscal Year: 2005

Detail Information

Publications291 found, 100 shown here

  1. ncbi Acoustic signature of the normal swallow: characterization by age, gender, and bolus volume
    Julie A Y Cichero
    Department of Speech Pathology and Audiology, University of Queensland, Brisbane, Australia
    Ann Otol Rhinol Laryngol 111:623-32. 2002
    ..There were also some gender-specific differences in the acoustic profile of the swallowing sound. It is anticipated that the results will provide a catalyst for further research into cervical auscultation...
  2. ncbi The effects of lingual exercise on swallowing in older adults
    Joanne Robbins
    Department of Medicine, University of Wisconsin Madison, Madison, Wisconsin, USA
    J Am Geriatr Soc 53:1483-9. 2005
    ..To determine the effects of an 8-week progressive lingual resistance exercise program on swallowing in older individuals, the most "at risk" group for dysphagia...
  3. ncbi Electrical stimulation for swallowing disorders caused by stroke
    M L Freed
    Respiratory Care Department, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland OH 44106, USA
    Respir Care 46:466-74. 2001
    ..We describe an alternative treatment consisting of transcutaneous electrical stimulation (ES) applied through electrodes placed on the neck...
  4. ncbi Reduced tongue pressure against the hard palate on the paralyzed side during swallowing predicts Dysphagia in patients with acute stroke
    Nobuko Hirota
    Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan
    Stroke 41:2982-4. 2010
    ..The present study investigated the relationship between tongue motor deficits and dysphagia in patients with acute stroke...
  5. ncbi Interrelationship of oral health status, swallowing function, nutritional status, and cognitive ability with activities of daily living in Japanese elderly people receiving home care services due to physical disabilities
    Michiko Furuta
    Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka, Japan
    Community Dent Oral Epidemiol 41:173-81. 2013
    ....
  6. ncbi An acoustic profile of normal swallowing
    Scott R Youmans
    Department of Communication Sciences and Disorders, Long Island University, Brooklyn Campus, 1 University Plaza, Brooklyn, NY 11201, USA
    Dysphagia 20:195-209. 2005
    ..These results could serve as a reference point for future studies into normal swallowing across multiple bolus consistencies and volumes and eventually be compared with disordered swallowing...
  7. ncbi Dysphagia following chemoradiation for locally advanced head and neck cancer
    N P Nguyen
    Radiation Oncology, VA North Texas Health Care System, Dallas 75216, USA
    Ann Oncol 15:383-8. 2004
    ..To assess the prevalence, severity and morbidity of dysphagia following concurrent chemoradiation for head and neck cancer...
  8. ncbi Oral and oropharyngeal perceptions of fluid viscosity across the age span
    Christina H Smith
    Department of Human Communication Science, University College London, London, England
    Dysphagia 21:209-17. 2006
    ..Men exhibited a more marked deterioration in sensitivity than women. This study contributes to the literature on oral and oropharyngeal perceptions and on aging. The results provide a basis for work with individuals with dysphagia...
  9. pmc Temporal variability in the deglutition literature
    Sonja M Molfenter
    Swallowing Rehabilitation Research Laboratory, Toronto Rehabilitation Institute, University Health Network, 550 University Avenue, Toronto, ON, Canada
    Dysphagia 27:162-77. 2012
    ..Trends emerged for factors of bolus size and participant age for some variables. Other potential sources of variability are discussed...
  10. ncbi Real time balanced turbo field echo Cine-MRI in the analysis of deglutition events and transit times
    S Karacay
    Department of Orthodontics, Dental Sciences Center, Gulhane, Military Medical Academy, Ankara, Turkey
    J Oral Rehabil 33:646-53. 2006
    ..In recent years, the movements of the anatomical structures that participate in deglutition have been investigated by several methods such as cineradiography, electromyography, electropalatography, ..
  11. pmc Aspiration and swallowing in Parkinson disease and rehabilitation with EMST: a randomized trial
    M S Troche
    PO Box 117420, University of Florida, Gainesville, FL 32611, USA
    Neurology 75:1912-9. 2010
    ..The current study's objective was to test the treatment outcome of a 4-week device-driven EMST program on swallow safety and define the physiologic mechanisms through measures of swallow timing and hyoid displacement...
  12. ncbi Aspiration rate following chemoradiation for head and neck cancer: an underreported occurrence
    Nam P Nguyen
    Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75216, USA
    Radiother Oncol 80:302-6. 2006
    ..We would like to assess the prevalence of aspiration before and following chemoradiation for head and neck cancer...
  13. ncbi Food transport and bolus formation during complete feeding sequences on foods of different initial consistency
    K M Hiiemae
    Department of Bioengineering and Neuroscience, and Institute for Sensory Research, Syracuse University, Syracuse, New York 13244 5290, USA
    Dysphagia 14:31-42. 1999
    ..There was no predictable tongue-palate contact at any time in the sequence. A new model for bolus formation and deglutition is proposed.
  14. ncbi Tongue movements during water swallowing in healthy young and older adults
    Catriona M Steele
    Toronto Rehabilitation Institute, Toronto, Ontario, Canada
    J Speech Lang Hear Res 52:1255-67. 2009
    ..In addition, changes were quantified in healthy tongue movements in response to specific differences in the nature of the swallowing task (discrete vs. sequential swallows)...
  15. ncbi The influence of chemical gustatory stimuli and oral anaesthesia on healthy human pharyngeal swallowing
    Carolyn Chee
    Manchester Medical School, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Chem Senses 30:393-400. 2005
    ..By 15 min all measures except sensory thresholds had returned to baseline values. Thus, swallowing function is highly influenced by chemosensory input, providing insight into how oral sensation regulates pharyngeal swallowing...
  16. ncbi Pattern of tongue pressure on hard palate during swallowing
    Takahiro Ono
    Osaka University Graduate School of Dentistry, Osaka, Japan
    Dysphagia 19:259-64. 2004
    ..These findings could aid assessment of the tongue movement of dysphagic patients during rehabilitation...
  17. ncbi Pharyngoesophageal reconstruction with the anterolateral thigh flap after total laryngopharyngectomy
    Peirong Yu
    Department of Plastic Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 116:1718-24. 2010
    ..The purpose of this study was to analyze the clinical and functional outcomes achieved using this technique...
  18. ncbi Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion
    A M Pedersen
    Copenhagen Gerodontological Oral Health Research Centre, Department of Clinical Oral Physiology, Anatomy, Pathology and Medicine, School of Dentistry, Denmark
    Oral Dis 8:117-29. 2002
    ..Finally, pathophysiological considerations of salivary dysfunction in relation to some GI functions are considered...
  19. ncbi Cerebral cortical representation of automatic and volitional swallowing in humans
    R E Martin
    School of Communication Sciences and Disorders, Faculty of Health Sciences, University of Western Ontario, London, Canada
    J Neurophysiol 85:938-50. 2001
    ..Activation of the insula was significantly lateralized to the right hemisphere for the voluntary saliva swallow, suggesting a functional hemispheric dominance of the insula for the processing of swallowing...
  20. ncbi Effect of citric acid and citric acid-sucrose mixtures on swallowing in neurogenic oropharyngeal dysphagia
    Cathy A Pelletier
    Department of Food Science and Technology, Cornell University, Ithaca, New York, USA
    Dysphagia 18:231-41. 2003
    ..The mechanisms for improved swallowing due to citric acid are not understood but may be due to increased gustatory and trigeminal stimulation of acid to the brainstem in neurologically impaired subjects...
  21. pmc Anatomy and physiology of feeding and swallowing: normal and abnormal
    Koichiro Matsuo
    Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Phipps 160 600 North Wolfe Street, Baltimore, MD 21287, USA
    Phys Med Rehabil Clin N Am 19:691-707, vii. 2008
    ..The goal of dysphagia rehabilitation is to identify and treat abnormalities of feeding and swallowing while maintaining safe and efficient alimentation and hydration...
  22. ncbi Reliability and validity of cervical auscultation: a controlled comparison using videofluoroscopy
    Paula Leslie
    School of Surgical and Reproductive Sciences, The Medical School, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Dysphagia 19:231-40. 2004
    ..The group consensus correctly identified 17 of the 20 clips so we may speculate that the swallow sound contains audible cues that should in principle permit reliable classification...
  23. pmc Physiological variability in the deglutition literature: hyoid and laryngeal kinematics
    Sonja M Molfenter
    Toronto Rehabilitation Institute, 550 University Avenue, Rm 12019, Toronto, ON M5G 2A2, Canada
    Dysphagia 26:67-74. 2011
    ..Potential sources of variation were identified, including statistical, methodological, stimulus-related, and participant-related sources...
  24. ncbi Hyoid and tongue surface movements in speaking and eating
    Karen M Hiiemae
    Department of Bioengineering and Neuroscience, Institute for Sensory Research, Syracuse University, Syracuse, NY 13244 5290, USA
    Arch Oral Biol 47:11-27. 2002
    ..These findings raise questions about the neuromotor control of hyoid position in the two behaviours and the biomechanics of the supralaryngeal vocal tract...
  25. ncbi Cervical auscultation synchronized with images from endoscopy swallow evaluations
    Paula Leslie
    Communication Science and Disorders, University of Pittsburgh, Pittsburgh, PA, USA
    Dysphagia 22:290-8. 2007
    ..More evaluation using imaging methods such as videofluoroscopy is required before this subjective technique is validated for clinical use by those assessing swallowing outside of a research context...
  26. ncbi Accuracy of the volume-viscosity swallow test for clinical screening of oropharyngeal dysphagia and aspiration
    Pere Clave
    Unitat d Exploracions Funcionals Digestives, Department of Surgery, Hospital de Mataro, Universitat Autonoma de Barcelona, Carretera de Cirera s n, 08304 Mataró, Spain
    Clin Nutr 27:806-15. 2008
    To determine the accuracy of the bedside volume-viscosity swallow test (V-VST) for clinical screening of impaired safety and efficacy of deglutition.
  27. ncbi Dynamic imaging of swallowing in a seated position using open-configuration MRI
    Yasutoshi Honda
    Department of Oral and Maxillofacial Radiology, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan
    J Magn Reson Imaging 26:172-6. 2007
    ..To assess the feasibility of dynamic MRI of swallowing in a seated position using an open-configuration MRI scanner, and to compare its capacity for motion analysis around the pharyngeal wall with that of videofluorography...
  28. ncbi Pressure profile similarities between tongue resistance training tasks and liquid swallows
    Catriona M Steele
    Toronto Rehabilitation Institute, 550 University Avenue, 12030, Toronto, ON, M5G 2A2, Canada
    J Rehabil Res Dev 47:651-60. 2010
    ..We propose that future research should explore the degree to which swallowing improvements are obtained from treatment protocols that emphasize these tasks...
  29. ncbi Influence of chin-down posture on tongue pressure during dry swallow and bolus swallows in healthy subjects
    Kazuhiro Hori
    Division of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, 2 5274 Gakkocho dori, Chuo Ku, Niigata 951 8514, Japan
    Dysphagia 26:238-45. 2011
    ..These results suggest that chin-down posture increases the tongue driving force for small boluses in healthy subjects, which can be interpreted to mean that oropharyngeal swallowing in a chin-down posture requires more effort...
  30. ncbi Real-time magnetic resonance imaging of normal swallowing
    Shuo Zhang
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, Gottingen, Germany
    J Magn Reson Imaging 35:1372-9. 2012
    ..To evaluate the use of a novel real-time magnetic resonance imaging (MRI) technique for the assessment of normal swallowing dynamics...
  31. ncbi Developmental patterns of rhythmic suck and swallow in preterm infants
    I H Gewolb
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore 21201, USA
    Dev Med Child Neurol 43:22-7. 2001
    ....
  32. pmc A randomized study of three interventions for aspiration of thin liquids in patients with dementia or Parkinson's disease
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, 3 358, Evanston, IL 60208, USA
    J Speech Lang Hear Res 51:173-83. 2008
    ....
  33. ncbi Brain stem control of swallowing: neuronal network and cellular mechanisms
    A Jean
    Laboratoire de Neurobiologie des Fonctions Vegetatives, Departement de Physiologie et Neurophysiologie, Faculté des Sciences et Techniques Saint Jérôme, Marseille, France
    Physiol Rev 81:929-69. 2001
    ..The mechanisms possibly involved in pattern generation and the possible flexibility of the swallowing central pattern generator are discussed...
  34. ncbi Dysphagia and aspiration in children
    James D Tutor
    Program in Pediatric Pulmonary Medicine, University of Tennessee Health Science Center, LeBonheur Children s Hospital, St Jude Children s Research Hospital, Memphis, Tennessee 38103, USA
    Pediatr Pulmonol 47:321-37. 2012
    ..Various disease processes that can result in dysphagia and aspiration in children are discussed. Finally, the various methods for diagnosis and treatment of dysphagia in children are reviewed...
  35. ncbi Dynamic MRI analysis of tumor and organ motion during rest and deglutition and margin assessment for radiotherapy of head-and-neck cancer
    Julie A Bradley
    Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI 53045, USA
    Int J Radiat Oncol Biol Phys 81:e803-12. 2011
    To quantify swallowing frequency and tumor and normal structure displacements during deglutition using dynamic magnetic resonance imaging (MRI) and to determine planning target volume (PTV) margins to account for resting and deglutition-..
  36. ncbi The influence of orolingual pressure on the timing of pharyngeal pressure events
    Catriona M Steele
    Toronto Rehabilitation Institute, Toronto, Canada
    Dysphagia 22:30-6. 2007
    ....
  37. ncbi Handy measurement for tongue motion and coordination with laryngeal elevation at swallowing
    K Tsuga
    Department of Removable Prosthodontics, Faculty of Dentistry, Hiroshima University, Hiroshima, Japan
    J Oral Rehabil 30:985-9. 2003
    ..There was considerable variation in these parameters between subjects. Though the data is limited, the device successfully and easily revealed certain aspects of tongue motion and coordination with laryngeal elevation...
  38. ncbi Pediatric dysphagia
    Maureen A Lefton-Greif
    Department of Pediatrics, Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins University School of Medicine, The David M Rubenstein Child Health Building, Baltimore, MD 21287, USA
    Phys Med Rehabil Clin N Am 19:837-51, ix. 2008
    ....
  39. ncbi Observation of the swallowing process by application of videofluoroscopy and real-time magnetic resonance imaging-consequences for retronasal aroma stimulation
    A Buettner
    Deutsche Forschungsanstalt fur Lebensmittelchemie, Lichtenbergstrasse 4, D 85748 Garching, Germany
    Chem Senses 26:1211-9. 2001
    ..Their effectiveness is related to the texture of the food as well as the amount of food material present in the oral cavity and, thereby, directly influences retronasal aroma perception...
  40. ncbi Tongue pressure patterns during water swallowing
    Daniel Kennedy
    Department of Oral Sciences, University of Otago, Dunedin, New Zealand
    Dysphagia 25:11-9. 2010
    ....
  41. ncbi Aspiration with dysphagia: the interaction between oropharyngeal and respiratory impairments
    Richard Morton
    Department of Paediatrics, Ronnie MacKeith Child Development Centre, Derbyshire Children s Hospital, Derby, United Kingdom
    Dysphagia 17:192-6. 2002
    ..Aspiration results from oropharyngeal impairments with inadequate respiratory integration. Further research is needed to investigate whether intervention to improve respiratory control can reduce aspiration in people with dysphagia...
  42. ncbi Rhombencephalic pathways and neurotransmitters controlling deglutition
    D Bieger
    Department of Medicine, Memorial University of Newfoundland, St John's, Newfoundland A1B 3V6, Canada
    Am J Med 111:85S-89S. 2001
    ..still incomplete, picture of the brain stem circuitry responsible for generating the motor patterns underlying deglutition and esophageal peristalsis in the rat...
  43. ncbi Simultaneous real-time measurements of mastication, swallowing, nasal airflow, and aroma release
    M Hodgson
    Division of Food Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leics, LE12 5RD, UK
    J Agric Food Chem 51:5052-7. 2003
    ..The volume of the retronasal route was estimated at 48 mL when swallowing and 72 mL when samples were chewed. The combination of techniques shows the effects of physiological processes on aroma release...
  44. ncbi Measures of tongue function related to normal swallowing
    Scott R Youmans
    Department of Communication Sciences and Disorders, Long Island University, Brooklyn, New York, USA
    Dysphagia 21:102-11. 2006
    ..In addition, maximum isometric pressures were correlated with mean swallowing pressures, and mean swallowing pressures and percentage of maximum isometric pressures used during swallowing were correlated between consistencies...
  45. ncbi Vocalization removal for improved automatic segmentation of dual-axis swallowing accelerometry signals
    Ervin Sejdic
    Bloorview Research Institute, Bloorview Kids Rehab and the Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada
    Med Eng Phys 32:668-72. 2010
    ..These results encourage further development of medical devices for the detection of swallowing difficulties...
  46. ncbi Evaluation and management of oropharyngeal Dysphagia in head and neck cancer
    Joy E Gaziano
    Speech Pathology Department, H Lee Moffitt Cancer Center Research Institute, Tampa, Florida 33612, USA
    Cancer Control 9:400-9. 2002
    ..Dysphagia can profoundly affect posttreatment recovery as it may contribute to aspiration pneumonia, dehydration, malnutrition, poor wound healing, and reduced tolerance to medical treatments...
  47. ncbi Neuroimaging evidence for cortical involvement in the preparation and in the act of swallowing
    R Dziewas
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Toronto, Ontario, M6A 2E1, Canada
    Neuroimage 20:135-44. 2003
    ..These new findings suggest a left hemispheric dominance for the cortical control of swallowing in humans...
  48. ncbi Primary closure versus radial forearm flap reconstruction after hemiglossectomy: functional assessment of swallowing and speech
    Hung Tao Hsiao
    Department of Plastic and Reconstructive Surgery, Mackay Memorial Hospital, 92 Chung San North Road, Section 2, Taipei, Taiwan
    Ann Plast Surg 49:612-6. 2002
    ..Evaluation of swallowing included the duration of deglutition, bolus volume, and ingestion rate...
  49. ncbi Temporal measurements of pharyngeal swallowing in normal populations
    Youngsun Kim
    School of Hearing, Speech and Language Sciences, College of Health and Human Services, Ohio University, Athens, Ohio 45701 2979, USA
    Dysphagia 20:290-6. 2005
    ..No gender differences were observed. These data on normal subjects will be used for comparisons with stroke patients in future research...
  50. ncbi Chemoradiation for patients with advanced oral cavity cancer
    Kerstin M Stenson
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Chicago, Chicago, Illinois, USA
    Laryngoscope 120:93-9. 2010
    ..The purpose of this study was to analyze survival, swallowing function, and incidence of osteoradionecrosis (ORN) of patients with stage III/IV OCC who have undergone primary concomitant chemoradiotherapy (CRT)...
  51. ncbi Particle size distribution of food boluses after mastication of six natural foods
    M A Peyron
    Institut National de la Recherche Agronomique, Theix, Station de Recherches sur la Viande, Saint Genes Champanelle, France
    J Dent Res 83:578-82. 2004
    ..A need for a bolus to be prepared with a precisely determined texture before it can be swallowed may explain the inter-subject variability of the masticatory function...
  52. ncbi Neuroleptic-induced dysphagia: case report and literature review
    Rainer Dziewas
    Department of Neurology, University Hospital of Munster, Munster, Germany
    Dysphagia 22:63-7. 2007
    ..After changing medication to fluphenazin, dysphagic symptoms resolved. The literature on EPS-related dysphagia, its demographic features, typical symptoms, diagnostic modalities, clinical course, and treatment options is reviewed...
  53. ncbi The challenge of mastication: preparing a bolus suitable for deglutition
    Anne Mishellany
    Déficiences, Incapacités et Désavantages en Santé Orale, DIDO, Faculté Dentaire, Clermont Ferrand, France
    Dysphagia 21:87-94. 2006
    ..particles size or cohesiveness, are continuously sensed during mastication and they are important in initiating deglutition. This study examined the following question: What is the condition of the bolus just before swallowing? Ten ..
  54. ncbi Chewing and food consistency: effects on bolus transport and swallow initiation
    Eiichi Saitoh
    Department of Rehabilitation Medicine, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan
    Dysphagia 22:100-7. 2007
    ..Consuming two-phase foods with both solid and liquid phases may increase the risk of aspiration in dysphagic individuals with impaired airway protective reflexes...
  55. ncbi Pretreatment, preoperative swallowing exercises may improve dysphagia quality of life
    Brian Daniel Kulbersh
    University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Laryngoscope 116:883-6. 2006
    ..Traditional dysphagia management strategies focus on post-treatment therapy. This study evaluated the utility of pretreatment swallowing exercises in improving post-treatment swallowing quality of life (QOL)...
  56. ncbi Pretreatment swallowing exercises improve swallow function after chemoradiation
    William R Carroll
    Division of Otolaryngology Head and Neck Surgery, Department of Radiology, University of Alabama at Birmingham UAB, BDB 1530 3rd Avenue, Birmingham, AL 35294, U S A
    Laryngoscope 118:39-43. 2008
    ..This study evaluates the effect of pretreatment swallowing exercises on posttreatment swallow function as measured by videofluoroscopy...
  57. pmc Tactile thermal oral stimulation increases the cortical representation of swallowing
    Inga K Teismann
    Department of Neurology, University of Muenster, 48149 Muenster, Germany
    BMC Neurosci 10:71. 2009
    ..Data were analyzed by means of synthetic aperture magnetometry (SAM) and the group analysis of individual SAM data was performed using a permutation test...
  58. ncbi Measuring intraoral pressure: adaptation of a dental appliance allows measurement during function
    Jules Kieser
    Department of Oral Sciences, University of Otago, Dunedin, New Zealand
    Dysphagia 23:237-43. 2008
    ..We also showed that there were significant negative pressures in the mouth during function, and that pressure profiles varied markedly between individuals...
  59. ncbi Standard values of maximum tongue pressure taken using newly developed disposable tongue pressure measurement device
    Yuri Utanohara
    Department of Advanced Prosthodontics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, 734 8553, Japan
    Dysphagia 23:286-90. 2008
    ..It may be concluded that maximum tongue pressures were reduced with primary aging. Males may become weaker with age at a faster rate than females; however, further decreases in strength were in parallel for male and female subjects...
  60. ncbi Thickened liquids: practice patterns of speech-language pathologists
    Jane Mertz Garcia
    Program in Communication Science and Disorders, Kansas State University, Manhattan 66506 1403, USA
    Am J Speech Lang Pathol 14:4-13. 2005
    ..Results highlight issues related to products and staff training, as well as perceptions concerning the factors that might affect patients' acceptance of and compliance with use of the products...
  61. pmc Swallowing and voice effects of Lee Silverman Voice Treatment (LSVT): a pilot study
    A el Sharkawi
    Northwestern University, Evanston, Illinois 60208, USA
    J Neurol Neurosurg Psychiatry 72:31-6. 2002
    ..To define the effects of Lee Silverman Voice Treatment (LSVT on swallowing and voice in eight patients with idiopathic Parkinson's disease...
  62. ncbi Comparison of effortful and noneffortful swallows in healthy middle-aged and older adults
    J A Hind
    Department of Medicine, University of Wisconsin Madison, USA
    Arch Phys Med Rehabil 82:1661-5. 2001
    ..To assess the effects of effortful swallowing, a common compensatory strategy for dysphagia, on the bolus and swallowing mechanism of middle-aged and older men and women...
  63. ncbi Screening for dysphagia and aspiration in acute stroke: a systematic review
    L Perry
    Mayday Healthcare, Faculty of Health and Social Care Sciences, Kingston University and St George s Hospital Medical School, Kingston upon Thames, Surrey, England
    Dysphagia 16:7-18. 2001
    ..While studies indicate current "best practice," in this important area of patient care further work is urgently required...
  64. pmc Effects of liquid stimuli on dual-axis swallowing accelerometry signals in a healthy population
    Joon Lee
    Bloorview Research Institute, 150 Kilgour Road, Toronto, Ontario, Canada
    Biomed Eng Online 9:7. 2010
    ..A variety of features were extracted in the time and time-frequency domains after swallow segmentation and pre-processing. A separate Friedman test was conducted for each feature and for each swallowing task...
  65. ncbi Hyoid motion during swallowing: factors affecting forward and upward displacement
    Ryo Ishida
    Department of Physical Medicine and Rehabilitation, Good Samaritan Hospital, Johns Hopkins University, Baltimore, Maryland 21239, USA
    Dysphagia 17:262-72. 2002
    ....
  66. ncbi A procedure for denoising dual-axis swallowing accelerometry signals
    Ervin Sejdic
    Bloorview Research Institute, Bloorview Kids Rehab and the Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada
    Physiol Meas 31:N1-9. 2010
    ..These results are important for the further development of medical devices based on dual-axis swallowing accelerometry signals...
  67. ncbi Brain stem control of the phases of swallowing
    Ivan M Lang
    Department of Medicine, Division of Gastroenterology and Hepatology, Dysphagia Institute Animal Research Laboratory, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Dysphagia 24:333-48. 2009
    ..The ventromedial nucleus of the NTS may govern the coupling of the pharyngeal phase to the esophageal phase of swallowing...
  68. ncbi Neuromuscular electrical stimulation (NMES) in stroke patients with oral and pharyngeal dysfunction
    Margareta Bülow
    Diagnostic Centre of Imaging and Functional Medicine, Malmo University Hospital, Malmo, Sweden
    Dysphagia 23:302-9. 2008
    ..The correlations between measurements were low. The patient's subjective experience of improvement had low correlation with the outcome from the objective evaluation...
  69. ncbi Time-dependent hemispheric shift of the cortical control of volitional swallowing
    Inga K Teismann
    Institute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149 Muenster, Germany
    Hum Brain Mapp 30:92-100. 2009
    ..However, until now, only deglutition related brain activation with low time resolution exceeding a time interval of 1 s has been reported...
  70. ncbi Hyoid movement during swallowing in older patients with dysphagia
    K A Kendall
    Department of Otolaryngology, University of California Davis, Medical Center, 2521 Stockton Blvd, Suite 7200, Sacramento, CA 95817, USA
    Arch Otolaryngol Head Neck Surg 127:1224-9. 2001
    ..To describe the timing, coordination, and extent of hyoid movement in a population of older adults with dysphagia and to evaluate the effect of hyoid movement on upper esophageal sphincter opening...
  71. ncbi Movement of the hyoid bone and the epiglottis during swallowing in patients with dysphagia from different etiologies
    Nam Jong Paik
    Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 300 Gumi dong Bundang gu, Seongnam 463 707, Republic of Korea
    J Electromyogr Kinesiol 18:329-35. 2008
    ....
  72. ncbi Effects of age, gender, bolus condition, viscosity, and volume on pharyngeal and upper esophageal sphincter pressure and temporal measurements during swallowing
    Susan G Butler
    Wake Forest University School of Medicine, Department of Otolaryngology Center for Voice and Swallowing Disorders, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Speech Lang Hear Res 52:240-53. 2009
    ..e., upper and lower) and upper esophageal sphincter (UES) pressures, durations, and onsets (i.e., onset of upper pharyngeal pressures relative to onsets of UES relaxations and onset of lower relative to upper pharyngeal pressures)...
  73. ncbi Effects of bolus consistency on timing and safety of swallow in patients with Parkinson's disease
    Michelle S Troche
    Department of Communication Sciences and Disorders, University of Florida, Gainesville, PO Box 117420, Florida 32611, USA
    Dysphagia 23:26-32. 2008
    ..The results demonstrated various significant differences and relationships among the dependent variables. Implications for further research and clinical practice are discussed...
  74. ncbi Laryngeal elevation achieved by neuromuscular stimulation at rest
    Theresa A Burnett
    Laryngeal and Speech Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1416, USA
    J Appl Physiol (1985) 94:128-34. 2003
    ..Paired muscle stimulation produced significantly greater elevation than single muscle stimulation and could assist with laryngeal elevation in dysphagic patients with reduced or delayed laryngeal elevation...
  75. ncbi Hyolaryngeal excursion as the physiological source of swallowing accelerometry signals
    D C B Zoratto
    Toronto Rehabilitation Institute, 500 University Avenue, Toronto, Ontario, M5G 2A2, Canada
    Physiol Meas 31:843-55. 2010
    ....
  76. pmc Sensory input pathways and mechanisms in swallowing: a review
    Catriona M Steele
    Toronto Rehabilitation Institute, 550 University Avenue, 12030, Toronto, ON, M5G 2A2, Canada
    Dysphagia 25:323-33. 2010
    ..By synthesizing the current state of research evidence and knowledge, we identify continuing gaps in our knowledge of these mechanisms and pose questions for future research...
  77. ncbi Evaluation of the anatomical and functional properties of deglutition with various kinetic high-speed MRI sequences
    A Anagnostara
    Institute of Neuroradiology, University Hospital of Zurich, Zurich, Switzerland
    J Magn Reson Imaging 14:194-9. 2001
    We evaluated various fast MR sequences for obtaining anatomical and dynamic functional information during deglutition. Seven healthy volunteers underwent MRI of the oropharynx during swallowing of an oral positive-contrast agent...
  78. ncbi Anthropometric and demographic correlates of dual-axis swallowing accelerometry signal characteristics: a canonical correlation analysis
    Fady Hanna
    Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada
    Dysphagia 25:94-103. 2010
    ..Given the limited sample size, our results should be interpreted with caution and replication studies with larger sample sizes are warranted...
  79. ncbi Maximum hyoid displacement in normal swallowing
    Youngsun Kim
    College of Health and Human Services, Ohio University, Grover Center, Athens, Ohio 45701 2979, USA
    Dysphagia 23:274-9. 2008
    ..Anterior displacement of the hyoid bone decreased with increasing age. This reduction may be related to muscle weakness. However, older people may adapt to preserve airway protection...
  80. ncbi Comparison of functional outcomes after endoscopic versus open-neck supraglottic laryngectomies
    Giorgio Peretti
    Department of Otolaryngology, University of Brescia, Brescia, Italy
    Ann Otol Rhinol Laryngol 115:827-32. 2006
    ..The aim of this study was to retrospectively evaluate functional outcomes after ESL in comparison with ONSL...
  81. ncbi Morphologic parameters of normal swallowing events using single-shot fast spin echo dynamic MRI
    Dana M Hartl
    Department of Otolaryngology Head and Neck Surgery, Institut Gustave Roussy, Villejuif, France
    Dysphagia 18:255-62. 2003
    ..The oral preparatory, oral, and oropharyngeal phases of deglutition were visible in all cases. No aspiration, reflux, or abnormal residue was observed...
  82. ncbi A novel handy probe for tongue pressure measurement
    Ryo Hayashi
    Department of Removable Prosthodontics, Faculty of Dentistry, Hiroshima University, Japan
    Int J Prosthodont 15:385-8. 2002
    ..The purpose of this study was to develop a handy probe to measure tongue pressure without fear of radiation or infection...
  83. ncbi Oropharyngeal swallow in younger and older women: videofluoroscopic analysis
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208, USA
    J Speech Lang Hear Res 45:434-45. 2002
    ..Older women also exhibited an increased range of motion relative to the old men. This increase may indicate a compensation for aging effects not seen in older men...
  84. ncbi Neural activation of swallowing and swallowing-related tasks in healthy young adults: an attempt to separate the components of deglutition
    Georgia A Malandraki
    Department of Speech and Hearing Science, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Hum Brain Mapp 30:3209-26. 2009
    ..The aim of the present investigation was to identify the neural activations of the different components of deglutition in healthy young adults using functional magnetic resonance imaging (fMRI)...
  85. pmc Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation
    Jeri A Logemann
    Department of Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA
    Head Neck 28:64-73. 2006
    ..The relationship between type of chemoradiation treatment, site of disease, and swallowing function has not been sufficiently examined in patients with head and neck cancer treated primarily with chemoradiation...
  86. ncbi Functional brain imaging of swallowing: an activation likelihood estimation meta-analysis
    Peter Soros
    School of Communication Sciences and Disorders, The University of Western Ontario, London, Ontario, Canada
    Hum Brain Mapp 30:2426-39. 2009
    ..Saliva swallowing more strongly involves premotor areas, which are crucial for the initiation and control of movements...
  87. pmc Volitional control of food transport and bolus formation during feeding
    Jeffrey B Palmer
    Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD 21287, United States
    Physiol Behav 91:66-70. 2007
    ..06). Under the command condition, stage II transport was delayed, and transport to the valleculae was inhibited. Volition alters swallow initiation in both the timing and location of the food bolus relative to the airway...
  88. ncbi Age-related changes in cortical swallowing processing
    Inga K Teismann
    Institute for Biomagnetism and Biosignalanalysis, University of Muenster, Muenster, Germany
    Neurobiol Aging 31:1044-50. 2010
    ..Aging effects on human deglutition have been found in several behavioral studies and are known to affect both the oral and pharyngeal phases of ..
  89. ncbi Correspondence between food consistency and suprahyoid muscle activity, tongue pressure, and bolus transit times during the oropharyngeal phase of swallowing
    Hiroshige Taniguchi
    Div of Dysphagia Rehabilitation, Niigata Univ Graduate School of Medical and Dental Sciences, Chuo Ku, Niigata 951 8514, Japan
    J Appl Physiol (1985) 105:791-9. 2008
    ..In addition, pharyngeal bolus transit is not dependent on the hardness of food but on its viscosity...
  90. pmc Cortical recovery of swallowing function in wound botulism
    Inga K Teismann
    Institute for Biomagnetism and Biosignalanalysis, University of Muenster, Muenster, Germany
    BMC Neurol 8:13. 2008
    ..However, little is known about cortical changes and compensation mechanisms accompanying swallowing pathology...
  91. ncbi Observation on the attachment of muscles onto the hyoid bone in human adults
    Naohiro Sonoda
    Department of Neurology, Gross Anatomy Section, Kagoshima University Graduate School of Medical and Dental Sciences 8 35 1 Sakuragaoka, Kagoshima 890 8544
    Okajimas Folia Anat Jpn 85:79-90. 2008
    ..From the aforementioned results, the following muscles were found attached to the hyoid bone in a further developed state: mylohyoid muscles, geniohyoid muscles, hyoglossal muscles, thyrohyoid muscles and hyoglossal muscles...
  92. ncbi Laryngeal penetration and aspiration during swallowing after the treatment of advanced oropharyngeal cancer
    M Boyd Gillespie
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston 29425, USA
    Arch Otolaryngol Head Neck Surg 131:615-9. 2005
    ..To determine whether laryngeal penetration and aspiration in oropharyngeal cancer survivors differ by treatment group...
  93. ncbi Effect of gender on swallow event duration assessed by videofluoroscopy
    Roberto Oliveira Dantas
    Department of Medicine, Medical School of Ribeirao Preto, University of Sao Paulo, 14049 900 Ribeirao Preto, SP, Brazil
    Dysphagia 24:280-4. 2009
    ..42 (0.25) s, women, 0.56 (0.27) s] compared with men (p < 0.05). We conclude that there are differences in swallowing between men and women, with women having a longer oropharyngeal transit than men for a 5-ml bolus...
  94. ncbi Neuroplasticity and swallowing
    Ruth E Martin
    Orofacial Neuroscience Laboratory, The School of Communication Sciences and Disorders, Elborn College, Department of Physiology and Pharmacology, The University of Western Ontario, London, ON, Canada
    Dysphagia 24:218-29. 2009
    ....
  95. ncbi Sonographic assessment of hyoid bone movement during swallowing: a study of normal adults with advancing age
    Koichi Yabunaka
    Department of Radiology, Katsuragi Hospital, 250 1 Makami Cho, Kishiwada, Osaka, 596 0842, Japan
    Radiol Phys Technol 4:73-7. 2011
    ..The movement of the hyoid bone during swallowing can be visualized by US. The trajectory of the hyoid bone in sagittal section indicated the capability of swallowing, and may detect some anomalies in swallowing...
  96. pmc Swallowing-related activities of respiratory and non-respiratory neurons in the nucleus of solitary tract in the rat
    Yoshiaki Saito
    Department of Neurobiology, Tokyo Metropolitan Institute for Neuroscience, Tokyo Women s Medical University, Japan
    J Physiol 540:1047-60. 2002
    ....
  97. ncbi Variability of swallow-associated sounds in adults and infants
    Eric W Reynolds
    Division of Neonatology, Department of Pediatrics, University of Kentucky School of Medicine, Lexington, KY 40536, USA
    Dysphagia 24:13-9. 2009
    ..Because successful feeding in infants is often used as a surrogate for normal development, the stability of swallow-associated sounds deserves more investigation as a potential marker for neurologic well-being...
  98. ncbi Impairment of deglutition reflex by acid-induced esophageal mucosal injury
    R J White
    Gastrointestinal Diseases Research Unit, Queen's University, Kingston, Ontario, Canada
    Dig Dis Sci 46:802-7. 2001
    ..The purpose of the present study was to examine the effect of esophagitis on the deglutition reflex in anesthetized opossums...
  99. pmc Intra-oral compartment pressures: a biofunctional model and experimental measurements under different conditions of posture
    Wilfried Engelke
    Dentistry Centre, Department of Maxillofacial Surgery, University of Gottingen, Gottingen, Germany
    Clin Oral Investig 15:165-76. 2011
    ....
  100. pmc Sensory regulation of swallowing and airway protection: a role for the internal superior laryngeal nerve in humans
    Samah Jafari
    Department of Neurology, University of Massachusetts Medical School, Worcester 01655, USA
    J Physiol 550:287-304. 2003
    ..This study was designed to evaluate the hypothesis that the ISLN afferent signal is necessary for normal deglutition and airway protection in humans...
  101. ncbi Morpho-functional patterns of physiologic oropharyngeal swallowing evaluated with dynamic fast MRI
    V Panebianco
    Department of Radiological Sciences, La Sapienza University, Rome, Italy
    Eur Arch Otorhinolaryngol 267:1461-6. 2010
    With the advent of dynamic fast MRI sequences the act of deglutition can be dynamically visualized in cine-mode...

Research Grants62

  1. COORDINATION OF RESPIRATION AND DEGLUTITION
    ADRIENNE PERLMAN; Fiscal Year: 2003
    ..and for each swallow, the direction of respiration preceding and following the swallow, the duration of deglutition apnea, and five additional RDT temporal measures will be obtained...
  2. Lingual and Laryngeal Muscle Plasticity
    NADINE PATTAKOS CONNOR; Fiscal Year: 2013
    ..lifespan and that age-related cranial musculoplasticity contributes to deficits observed in vocalization and deglutition. We hypothesize that mechanisms are alterations in lingual and laryngeal muscle regenerative capacity, ..
  3. CHD1, Chromatin Dynamics, and Salivary Gland Differentiation
    JOSEPH ADAM HALL; Fiscal Year: 2010
    ..Hyposecretion of mucins by the SLGs results in xerostomia, characterized by difficulty in phonation and deglutition, mucosal ulcerations, and an increase in the frequency of dental caries...
  4. Manual Control of the Upper Esophageal Sphincter
    Peter Belafsky; Fiscal Year: 2013
    ..in medical devices for other organ systems, there is currently no device available to assist with the act of deglutition. Current therapeutic options include swallowing therapy, diet modification, non-oral feeding and invasive ..
  5. Effects of Aging on Anticipatory Functional Synergies Activated in Deglutition
    SAMANTHA EVE SHUNE; Fiscal Year: 2013
    ..synergistic muscle patterns involving the hand/arm, lips, and jaw that are present during the pre-oral stage of deglutition in younger and older adults;and (2) to determine the influence of modifications in non-oropharyngeal sensory ..
  6. Exercise as a Treatment for Tongue Weakness
    NADINE PATTAKOS CONNOR; Fiscal Year: 2013
    ..in 3 extrinsic tongue muscles of old and middle-aged rats that will facilitate improvements in measures in deglutition. We will test this hypothesis in a rat model by comparing physiological, behavioral, biochemical, molecular and ..
  7. Neuromuscular control of the human tongue
    E Fiona Bailey; Fiscal Year: 2013
    ..Until recently, almost all studies of lingual muscle function whether in speech, respiration or deglutition have concerned themselves with the study of whole muscle electromyographic (EMG) activities...
  8. RESPIRATORY SYSTEM INTEGRATION BY THE BRAINSTEM
    ALBERT BERGER; Fiscal Year: 2002
    ..Also, HMs are important in other behaviors including mastication, swallowing (deglutition), sucking, licking, and vocalization...
  9. PROLINE-RICH GLYCOPROTEIN MASTICATORY LUBRICATION
    Lawrence Tabak; Fiscal Year: 1991
    ..surfaces in relation to the soft tissues of the mouth leads to difficulty in phonation, mastication and deglutition. Moreover, the absence of a lubricating interface between soft and hard (natural or prosthetic) surfaces of the ..
  10. Lingual Mechanical Function During Swallowing
    Richard Gilbert; Fiscal Year: 2005
    ..During normal deglutition, the tongue first configures, then propels the ingested bolus from the oral cavity retrograde to the pharynx...
  11. MOLECULAR BASIS OF IDIOPATHIC DRY MOUTH
    JAMES MELVIN; Fiscal Year: 2004
    ..of salivary function comprises the sensation of oral dryness, difficulties in speech, mastication and deglutition, increased susceptibilities to oral microbial diseases such as caries and fungal infections, and reduced ..
  12. ESOPHAGEAL MOTILITY AND AIRWAY DEFENSES AMONG INFANTS
    SUDARSHAN JADCHERLA; Fiscal Year: 2003
    ..Specific Aim 1 will determine maturational changes in the relationship between deglutition and airway safety...
  13. Detection of chewing and swallowing to estimate eating patterns and energy intake
    Edward Sazonov; Fiscal Year: 2006
    ..investigation which will provide preliminary data that objective observations of mastication (chewing) and deglutition (swallowing) by a wearable, non-intrusive monitoring device can provide statistically reliable estimates of ..
  14. DIFFERENCES IN SWALLOW MECHANICS IN INFANTS
    Rebecca German; Fiscal Year: 2005
    ..funding period, we added to the understanding of muscle activity and oropharyngeal kinematics in infant deglutition. However, the role of the majority of muscles during emptying of the valleculae and in the transport of the ..
  15. Dysphagia in Induced Parkinson's Disease
    Rebecca German; Fiscal Year: 2005
    ..g. Wintzen et al., 1994). Synchronous electromyographic data from the muscles critical for normal deglutition, while essential for characterizing the motor patterns, and ultimately the neural control of swallowing, are ..
  16. Oropharyngeal Function After Radiotherapy with IMRT
    Jerilyn A Logemann; Fiscal Year: 2010
    ..This project attempts to quantify the swallow problems associated with this specific treatment and the effects of interventions for these swallow problems. ..
  17. Effects of LSVT on Dysphagia in Parkinson's Disease
    Jerilyn Logemann; Fiscal Year: 2003
    ..This application proposes to generate pilot data on the effects of LSVT on aspiration, a potentially dangerous and costly side effect of dysphagia in Parkinson's disease. ..
  18. Effects of Swallowing Therapy in Head and Neck Cancer
    Jerilyn Logemann; Fiscal Year: 2006
    ....
  19. Anatomic and Mechanical Variables of the EGJ in GERD
    John Pandolfino; Fiscal Year: 2006
    ..These changes will improve diagnostic accuracy of pH monitoring and also help determine the relationship between anatomical and mechanical variants and acid reflux. ..
  20. Measurement model for respiratory-swallowing impairment
    Bonnie Martin Harris; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  21. Stadardized Assesment of Swallowing Impairment
    Bonnie Martin Harris; Fiscal Year: 2007
    ..abstract_text> ..
  22. RESPIRATORY AND LARYNGEAL DYNAMICS DURING SWALLOW
    Bonnie Martin Harris; Fiscal Year: 2002
    ..Cluster analysis will be applied to identify critical clusters of respiratory-swallowing dynamics. Mixed- effects analysis of variance will estimate the key study parameters of age group specific durations and variability. ..
  23. Comparison of Two Therapies for UES Dysphagia
    Reza Shaker; Fiscal Year: 2004
    ..anteroposterior and lateral diameter of maximum deglutitive UES opening, and b. maximum deglutitive laryngeal anterior and superior excursions. ..
  24. Tongue-Jaw Linkages in Feeding
    Jeffrey Palmer; Fiscal Year: 2005
    ....
  25. CONTROL OF BREATHING IN RECOVERY FROM APNEA
    Bradley Thach; Fiscal Year: 2008
    ..Louis, MO.) of infants dying suddenly and unexpectedly to determine if post mortem body temperature indicates involvement of overheating or disorders of thermoregulation in SIDS. [unreadable] [unreadable]..
  26. Oral Feeding in Infants
    Chantal Lau; Fiscal Year: 2009
    ..The secondary outcomes will be attainment of specific feeding milestones at 3, 6, 12, 18, and 24 months corrected age. ..
  27. LEPTIN & NEUROPEPTIDE-Y ALTERS FETAL SWALLOWING ACTIVITY
    Michael Ross; Fiscal Year: 2002
    ..In addition, these studies represent a model to examine the development and function of neuronal pathways and mechanisms which regulate fetal physiology. ..
  28. Fetal Swallowing: Central Dipsogenic Mechanisms
    Michael Ross; Fiscal Year: 2007
    ..Furthermore, these studies represent a model to examine the development and function of neuronal pathways and mechanisms regulating fetal physiology. ..
  29. MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 2002
    ..The goal of this project is to determine critical efficacy and fetal safety issues central to maternal DDAVP treatment, prior to widespread clinical use in human pregnancies with oligohydramnios. ..
  30. Coordination of Respiration with Deglutition & Phonation in Ataxia-Telangiectasia
    Maureen Lefton Greif; Fiscal Year: 2007
    ..We will use Respirodeglutometric (RDT) instrumentation to characterize the respiration during deglutition in patients with A-T...
  31. PREVENTION AND TREATMENT OF HUMAN OLIGOHYDRAMNIOS
    Michael Ross; Fiscal Year: 2001
    ..e., failure to reset osmolality threshold). This proposal will aid in the development of markers of prediction and therapeutic approaches to the prevention and treatment of human oligohydramnios. ..
  32. Realtime Internet Evaluation of Oropharyngeal Swallowing
    ADRIENNE PERLMAN; Fiscal Year: 2007
    ..Confirmation of the reliability of the telefluoroscopic evaluation can result in equity of access for underserved groups for whom SLPs with expertise in dysphagia diagnosis are locally unavailable. [unreadable] [unreadable] [unreadable]..
  33. Fetal Membrane AQP Expression/Amniotic Fluid Regulation
    Michael Ross; Fiscal Year: 2004
    ..Our objective is to determine the regulatory mechanisms of fetal membrane AQP expression and delineate the role of AQPs in AF homeostasis. ..
  34. Biomechanical Evaluation of Eustachian Tube Dysfunction
    Samir N Ghadiali; Fiscal Year: 2010
    ..This information is vital to the development of novel treatment therapies that seek to restore normal ET function in patients with OM. ..
  35. Eating Disorder Prevention Program Effectiveness Trial
    Eric Stice; Fiscal Year: 2009
    ..g. will use random assignment, an attention control condition, blinded diagnostic interviews, multiple-reporter data, and a long-term follow-up). ..
  36. Evaluating Nicotine Lozenges for Treatment of Smokeless Tobacco Addiction
    Jon Ebbert; Fiscal Year: 2009
    ..No drug therapies have been shown to be effective for helping smokeless tobacco users quit for good. The purpose of this study is to test drugs that can be used to help smokeless tobacco users quit for good. ..
  37. Neural basis of learned food aversion and nausea
    CHARLES HORN; Fiscal Year: 2009
    ..Effective treatment of nausea may substantially improve the quality of life for patients with chronic disease. ..
  38. Oxidative Stress and the Pathogenesis of Sarcopenia and Disability in Older Women
    Richard Semba; Fiscal Year: 2008
    ..AGEs are a potentially modifiable risk factor, as circulating AGEs can be lowered by dietary modification and by pharmacological intervention. ..
  39. Reinnervation of Paralyzed Muscle by Nerve-Muscle-Endplate Band Grafting
    Liancai Mu; Fiscal Year: 2011
    ..Our preliminary work showed that this technique results in better outcomes than currently used methods. The data obtained from this research is useful for future clinical application to treat muscle paralysis. ..
  40. NEURAL BASIS OF TASTE ELICITED INGESTION AND REJECTION
    JOSEPH TRAVERS; Fiscal Year: 2009
    ..Understanding the neurological basis of the fundamental biological decision ingest or reject food will contribute to the eventual solution of these chronic debilitating disorders. ..
  41. Neurobiological Circuits of Gain and Loss During Risky Decision Making
    Gregory S Berns; Fiscal Year: 2010
    ....
  42. Hepcidin and the pathogenesis of anemia in older adults.
    Richard D Semba; Fiscal Year: 2010
    ..This study should provide new insight into the epidemiology and biological mechanisms of anemia among older adults and help identify strategies aimed at the prevention and treatment of anemia. ..
  43. Peripheral Nerve Implementation of Functional Neuroprostheses
    DUSTIN TYLER; Fiscal Year: 2008
    ..We expect this work will make a significant impact in upper extremity FES applications and pave the path to other applications, such as neural interfaces for amputee prosthetics. [unreadable] [unreadable] [unreadable]..
  44. NEUROMUSCULAR STRATEGIES FOR HUMAN TONGUE MOVEMENT
    ALAN SOKOLOFF; Fiscal Year: 2007
    ..These studies will provide important information on the neurobiology of the tongue motor system and will provide the first direct tests of the molecular and physiological bases of aging of the human tongue motor system. ..
  45. CONTROL OF FEEDING BEHAVIOR--HEPATIC AFFERENT SIGNALING
    CHARLES HORN; Fiscal Year: 2002
    ..Results from this project may contribute to a better understanding of metabolic stimuli that are sensed by the nervous system, and may elucidate neural controls that are involved in obesity, anorexia, and diabetes. ..
  46. ETIOLOGY OF BULIMIC PATHOLOGY--MULTIMETHOD INVESTIGATION
    Eric Stice; Fiscal Year: 2002
    ..Agras' and Taylor's labs, (2) learn state-of- the-art treatments for eating pathology and other adolescent psychopathology, (3) take courses in quantitative techniques, methodology, and ethics, and (4) receive training in grant writing. ..
  47. Estrogen, Inflammation and Cardiovascular Risk
    David Reuben; Fiscal Year: 2003
    ..These findings may provide substantial insight into why CEE appears to promote early but protect against late cardiovascular effects. ..
  48. NEUROIMAGING OG NOVELTY DETECTION IN COCAINE DEPENDENCE
    Gregory Berns; Fiscal Year: 2003
    ..abstract_text> ..
  49. ADJUNCT VITAMIN A THERAPY FOR TUBERCULOSIS AND HIV/AIDS
    Richard Semba; Fiscal Year: 2005
    ....
  50. Brief Dental Office Intervention with Tobacco Quitline
    Jon Ebbert; Fiscal Year: 2005
    ..S. adult population smoking; and 3) 75% of smokers quitting for at least one day or longer because they are trying to quit. ..
  51. METHYLPHENIDATE STUDY IN YOUNG CHILDREN WITH PDD
    Jaswinder Ghuman; Fiscal Year: 2005
    ..The proposed training program will allow the candidate to acquire sufficient expertise to carry out future treatment intervention studies in a very specialized area. ..
  52. Expiratory muscle training in patients with Parkinson's
    Christine Sapienza; Fiscal Year: 2006
    ..The goals of the grant meet the mission of the R21. Its potential impact is high due to the therapy program's innovative nature and potential cost-effectiveness as a treatment approach. ..
  53. Iron Deficiency and Anemia in HIV and HCV-Infected Women
    Richard Semba; Fiscal Year: 2005
    ..S. and elsewhere. ..
  54. PERIPHERAL NMDA RECEPTORS AND TMD PAIN MECHANISMS
    Barry Sessle; Fiscal Year: 2006
    ..abstract_text> ..
  55. Regulation of the Cough Reflex
    Donald Bolser; Fiscal Year: 2006
    ..Furthermore, this project will test the proposed roles of medullary and spinal cellular elements that contribute to the generation and control of expiratory motor discharge during cough. ..
  56. Physiology of Swallowing and Airway Protection
    David Paydarfar; Fiscal Year: 2006
    ..We will stimulate the ISLN (using optimum parameters from Aim 3) in patients with neurogenic dysphagia caused by focal cerebral damage, and we will test for improvement in swallowing and decrease in aspiration. ..
  57. Bioengineering Analysis of Muscle Mechanics & Metabolism
    SRBOLJUB MIJAILOVICH; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  58. Attention, Memory, and Executive Function in Fragile X
    Donald Bailey; Fiscal Year: 2006
    ..abstract_text> ..
  59. Feeding of the ELBW and VLBW Preterm Infants After Hospital Discharge
    ALICE HILL; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  60. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
    ..The relationship between mastitis and breastmilk HIV load and the epidemiology and microbiology of mastitis will be examined in a new cohort of HIV-infected lactating women. ..