symbiosis

Summary

Summary: The living together of organisms of different species.

Top Publications

  1. ncbi A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium
    Luciano A Moreira
    School of Biological Sciences, The University of Queensland, Brisbane QLD 4072, Australia
    Cell 139:1268-78. 2009
  2. ncbi Wolbachia: master manipulators of invertebrate biology
    John H Werren
    Biology Department, University of Rochester, Rochester, New York, New York 14627, USA
    Nat Rev Microbiol 6:741-51. 2008
  3. ncbi Extreme genome reduction in symbiotic bacteria
    John P McCutcheon
    University of Montana, Division of Biological Sciences, 32 Campus Drive, HS104, Missoula, Montana 59812, USA
    Nat Rev Microbiol 10:13-26. 2012
  4. ncbi The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism
    E Virginia Armbrust
    School of Oceanography, University of Washington, Seattle, WA 98195, USA
    Science 306:79-86. 2004
  5. ncbi Horizontal gene transfer in eukaryotic evolution
    Patrick J Keeling
    Department of Botany, University of British Columbia, Vancouver, British Columbia V6T 1Z, Canada
    Nat Rev Genet 9:605-18. 2008
  6. ncbi Genomics and evolution of heritable bacterial symbionts
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Annu Rev Genet 42:165-90. 2008
  7. ncbi The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis
    F Martin
    UMR 1136, INRA Nancy Université, Interactions Arbres Microorganismes, INRA Nancy, 54280 Champenoux, France
    Nature 452:88-92. 2008
  8. ncbi The gut bacteria of insects: nonpathogenic interactions
    R J Dillon
    Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom
    Annu Rev Entomol 49:71-92. 2004
  9. ncbi Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes
    Julie C Dunning Hotopp
    Institute for Genomic Research, J Craig Venter Institute, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 317:1753-6. 2007
  10. pmc A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids
    Jan Janouskovec
    Department of Botany, University of British Columbia, Vancouver, BC, Canada
    Proc Natl Acad Sci U S A 107:10949-54. 2010

Detail Information

Publications386 found, 100 shown here

  1. ncbi A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium
    Luciano A Moreira
    School of Biological Sciences, The University of Queensland, Brisbane QLD 4072, Australia
    Cell 139:1268-78. 2009
    ..We suggest that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases...
  2. ncbi Wolbachia: master manipulators of invertebrate biology
    John H Werren
    Biology Department, University of Rochester, Rochester, New York, New York 14627, USA
    Nat Rev Microbiol 6:741-51. 2008
    ..Here, we review the basic biology of Wolbachia, with emphasis on recent advances in our understanding of these fascinating endosymbionts...
  3. ncbi Extreme genome reduction in symbiotic bacteria
    John P McCutcheon
    University of Montana, Division of Biological Sciences, 32 Campus Drive, HS104, Missoula, Montana 59812, USA
    Nat Rev Microbiol 10:13-26. 2012
    ..These discoveries have implications for the concept of minimal genomes, the origins of cellular organelles, and studies of symbiosis and host-associated microbiota.
  4. ncbi The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism
    E Virginia Armbrust
    School of Oceanography, University of Washington, Seattle, WA 98195, USA
    Science 306:79-86. 2004
    ....
  5. ncbi Horizontal gene transfer in eukaryotic evolution
    Patrick J Keeling
    Department of Botany, University of British Columbia, Vancouver, British Columbia V6T 1Z, Canada
    Nat Rev Genet 9:605-18. 2008
    ..Major recent trends include the important role of HGT in adaptation to certain specialized niches and the highly variable impact of HGT in different lineages...
  6. ncbi Genomics and evolution of heritable bacterial symbionts
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Annu Rev Genet 42:165-90. 2008
    ..Among the most far-reaching impacts of widespread heritable symbiosis is that it may promote speciation by increasing reproductive and ecological isolation of host populations, and ..
  7. ncbi The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis
    F Martin
    UMR 1136, INRA Nancy Université, Interactions Arbres Microorganismes, INRA Nancy, 54280 Champenoux, France
    Nature 452:88-92. 2008
    ..role of ectomycorrhizae in plant development and physiology, allowing the full ecological significance of this symbiosis to be explored. Here we report the genome sequence of the ectomycorrhizal basidiomycete Laccaria bicolor (Fig...
  8. ncbi The gut bacteria of insects: nonpathogenic interactions
    R J Dillon
    Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom
    Annu Rev Entomol 49:71-92. 2004
    ....
  9. ncbi Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes
    Julie C Dunning Hotopp
    Institute for Genomic Research, J Craig Venter Institute, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 317:1753-6. 2007
    ..Therefore, heritable lateral gene transfer occurs into eukaryotic hosts from their prokaryote symbionts, potentially providing a mechanism for acquisition of new genes and functions...
  10. pmc A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids
    Jan Janouskovec
    Department of Botany, University of British Columbia, Vancouver, BC, Canada
    Proc Natl Acad Sci U S A 107:10949-54. 2010
    ..g., ciliates, Cryptosporidium, and Phytophthora)...
  11. ncbi Rapid spread of a bacterial symbiont in an invasive whitefly is driven by fitness benefits and female bias
    Anna G Himler
    Center for Insect Science, The University of Arizona, Post Office Box 210106, Tucson, AZ 85721 0106, USA
    Science 332:254-6. 2011
    ..Symbiont invasions such as this represent a sudden evolutionary shift for the host, with potentially large impacts on its ecology and invasiveness...
  12. pmc Sponge-associated microorganisms: evolution, ecology, and biotechnological potential
    Michael W Taylor
    Department of Microbial Ecology, University of Vienna, Althanstr 14, A 1090 Vienna, Austria
    Microbiol Mol Biol Rev 71:295-347. 2007
    ..We review the status of this important field, outlining the various approaches (e.g., cultivation, cell separation, and metagenomics) which have been employed to access the chemical wealth of sponge-microbe associations...
  13. ncbi Phylogenetic validation of the genera Angomonas and Strigomonas of trypanosomatids harboring bacterial endosymbionts with the description of new species of trypanosomatids and of proteobacterial symbionts
    Marta M G Teixeira
    Department of Parasitology, ICB, University of Sao Paulo USP, Sao Paulo, 05508 000, SP, Brazil
    Protist 162:503-24. 2011
    ..The congruence of the phylogenetic trees of trypanosomatids and their symbionts support a co-divergent host-symbiont evolutionary history...
  14. pmc Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis
    Alistair C Darby
    Institute of Integrative Biology and the Centre for Genomic Research, Biosciences Building, University of Liverpool, Liverpool, Merseyside L69 7ZB, United Kingdom
    Genome Res 22:2467-77. 2012
    ..The symbiosis between filariae and Wolbachia is obligate, although the basis of this dependency is not fully understood...
  15. ncbi A gene expression atlas of the model legume Medicago truncatula
    Vagner A Benedito
    Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK 73401, USA
    Plant J 55:504-13. 2008
    ..The data presented here represent an unparalleled resource for legume functional genomics, which will accelerate discoveries in legume biology...
  16. ncbi Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite
    Falk Warnecke
    DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, California 94598, USA
    Nature 450:560-5. 2007
    ..Our results underscore how complex even a 1-microl environment can be...
  17. ncbi Cyanophora paradoxa genome elucidates origin of photosynthesis in algae and plants
    Dana C Price
    Department of Ecology, Evolution, and Natural Resources, Rutgers University, New Brunswick, NJ 08901, USA
    Science 335:843-7. 2012
    ..paradoxa and other Plantae. Apparently, Chlamydia-like bacteria donated genes that allow export of photosynthate from the plastid and its polymerization into storage polysaccharide in the cytosol...
  18. ncbi How host-microbial interactions shape the nutrient environment of the mammalian intestine
    Lora V Hooper
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Annu Rev Nutr 22:283-307. 2002
    ..These and other studies underscore the importance of understanding precisely how nutrient metabolism serves to establish and sustain symbiotic relationships between mammals and their bacterial partners...
  19. pmc The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine
    Shipra Vaishnava
    Department of Immunology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
    Science 334:255-8. 2011
    ..Together, our findings reveal that RegIIIγ is a fundamental immune mechanism that promotes host-bacterial mutualism by regulating the spatial relationships between microbiota and host...
  20. pmc Multilocus sequence typing system for the endosymbiont Wolbachia pipientis
    Laura Baldo
    Department of Biology, University of California, 900 University Avenue, Riverside, CA 92521, USA
    Appl Environ Microbiol 72:7098-110. 2006
    ..The central database for storing and organizing Wolbachia bacterial and host information can be accessed at http://pubmlst.org/wolbachia/...
  21. pmc The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster
    Luis Teixeira
    Department of Genetics, University of Cambridge, Cambridge, United Kingdom
    PLoS Biol 6:e2. 2008
    ..melanogaster. The induced resistance to natural viral pathogens may explain Wolbachia prevalence in natural populations and represents a novel Wolbachia-host interaction...
  22. ncbi Horizontal gene transfer from diverse bacteria to an insect genome enables a tripartite nested mealybug symbiosis
    Filip Husník
    Faculty of Science, University of South Bohemia and Institute of Parasitology, Biology Centre ASCR, České Budějovice 370 05, Czech Republic
    Cell 153:1567-78. 2013
    ..Our results thus indicate that the functioning of this three-way symbiosis is dependent on genes from at least six lineages of organisms and reveal a path to intimate endosymbiosis ..
  23. ncbi Evolutionary microbial genomics: insights into bacterial host adaptation
    Christina Toft
    Department of Molecular Evolution, Uppsala University, 752 36 Uppsala, Sweden
    Nat Rev Genet 11:465-75. 2010
    ....
  24. ncbi Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti
    Conor J McMeniman
    School of Integrative Biology, University of Queensland, Brisbane 4072, Australia
    Science 323:141-4. 2009
    ..Our data suggest that targeting mosquito age with inherited Wolbachia infections may be a viable strategy to reduce the transmission of pathogens such as dengue viruses...
  25. pmc How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model
    Kathryn M Jones
    Department of Biology, Massachusetts Institute of Technology, Building 68, Room 633, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Nat Rev Microbiol 5:619-33. 2007
    ....
  26. ncbi Antimicrobial peptides keep insect endosymbionts under control
    Frédéric H Login
    INSA Lyon, INRA, UMR203 BF2I, Biologie Fonctionnelle Insectes et Interactions, F 69621 Villeurbanne, France
    Science 334:362-5. 2011
    ....
  27. ncbi Commensal host-bacterial relationships in the gut
    L V Hooper
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 63110, USA
    Science 292:1115-8. 2001
    ....
  28. ncbi Fungal endophytes: diversity and functional roles
    R J Rodriguez
    US Geological Survey, Seattle, WA, USA
    New Phytol 182:314-30. 2009
    ..Using this framework, we contrast the life histories, interactions with hosts and potential roles in plant ecophysiology of C- and NC-endophytes, and highlight several key questions for future work in endophyte biology...
  29. ncbi An ecological and evolutionary perspective on human-microbe mutualism and disease
    Les Dethlefsen
    Department of Microbiology and Immunology, Stanford University, Stanford, California 94305, USA
    Nature 449:811-8. 2007
    ..In this way, looking to ecological and evolutionary principles might provide new strategies for restoring and maintaining human health...
  30. pmc Facultative bacterial symbionts in aphids confer resistance to parasitic wasps
    Kerry M Oliver
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 100:1803-7. 2003
    ..This strong interaction between a symbiotic bacterium and a host natural enemy provides a mechanism for the persistence and spread of symbiotic bacteria...
  31. pmc The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions
    Malin E V Johansson
    Department of Medical Biochemistry, University of Gothenburg, 405 30 Gothenburg, Sweden
    Proc Natl Acad Sci U S A 108:4659-65. 2011
    ..This observation that normal human individuals carry a uniform MUC2 mucin glycan array in colon may indicate such a specific selection...
  32. ncbi Algae acquire vitamin B12 through a symbiotic relationship with bacteria
    Martin T Croft
    Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, UK
    Nature 438:90-3. 2005
    ..The source of cobalamin seems to be bacteria, indicating an important and unsuspected symbiosis.
  33. ncbi Périgord black truffle genome uncovers evolutionary origins and mechanisms of symbiosis
    Francis Martin
    INRA, UMR 1136, INRA Nancy Université, Interactions Arbres Microorganismes, 54280 Champenoux, France
    Nature 464:1033-8. 2010
    ..Identification of processes that condition and trigger fruit body and symbiosis formation, ultimately leading to efficient crop production, will be facilitated by a thorough analysis of ..
  34. ncbi Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila
    Ji Hwan Ryu
    Division of Molecular Life Science, Ewha Woman s University and National Creative Research Initiative Center for Symbiosystem, Seoul 120 750, South Korea
    Science 319:777-82. 2008
    ..These results reveal that a specific genetic deficiency within a host can profoundly influence the gut commensal microbial community and host physiology...
  35. ncbi The role of microorganisms in coral health, disease and evolution
    Eugene Rosenberg
    Department of Molecular Microbiology, Tel Aviv University, Ramat Aviv, Israel 69978
    Nat Rev Microbiol 5:355-62. 2007
    ..Generalization of the coral probiotic hypothesis has led us to propose the hologenome theory of evolution...
  36. ncbi The unseen majority: soil microbes as drivers of plant diversity and productivity in terrestrial ecosystems
    Marcel G A van der Heijden
    Department of Animal Ecology, Faculty of Earth and Life Sciences, Institute of Ecological Science, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
    Ecol Lett 11:296-310. 2008
    ..Overall, this review shows that soil microbes must be considered as important drivers of plant diversity and productivity in terrestrial ecosystems...
  37. pmc Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle
    Ewen F Kirkness
    J Craig Venter Institute, Rockville, MD 20850, USA
    Proc Natl Acad Sci U S A 107:12168-73. 2010
    ..Thus, the body louse genome project offers unique information and tools to use in advancing understanding of coevolution among vectors, symbionts, and pathogens...
  38. pmc Wolbachia symbiont infections induce strong cytoplasmic incompatibility in the tsetse fly Glossina morsitans
    Uzma Alam
    Yale University, School of Public Health, Division of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America
    PLoS Pathog 7:e1002415. 2011
    ..Alternatively, the availability of males that are reproductively incompatible with natural populations can enhance the efficacy of the ongoing sterile insect technique (SIT) applications by eliminating the need for chemical irradiation...
  39. pmc Obligate symbionts activate immune system development in the tsetse fly
    Brian L Weiss
    Division of Epidemiology of Microbial Diseases, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    J Immunol 188:3395-403. 2012
    ..Our finding that molecular components of Wigglesworthia exhibit immunostimulatory activity within tsetse is representative of a novel evolutionary adaptation that steadfastly links an obligate symbiont with its host...
  40. ncbi Lymphatic filariasis and onchocerciasis
    Mark J Taylor
    Liverpool School of Tropical Medicine, Liverpool, UK
    Lancet 376:1175-85. 2010
    ..Most filarial species that infect people co-exist in mutualistic symbiosis with Wolbachia bacteria, which are essential for growth, development, and survival of their nematode hosts...
  41. ncbi A microbial symbiosis factor prevents intestinal inflammatory disease
    Sarkis K Mazmanian
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Nature 453:620-5. 2008
    ..Harnessing the immunomodulatory capacity of symbiosis factors such as PSA might potentially provide therapeutics for human inflammatory disorders on the basis of ..
  42. pmc Genome evolution of Wolbachia strain wPip from the Culex pipiens group
    Lisa Klasson
    Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, Oxford, United Kingdom
    Mol Biol Evol 25:1877-87. 2008
    ..This host-Wolbachia system, with its complex patterns of sterility induced between populations, now provides an excellent model for unraveling the molecular systems underlying host reproductive manipulation...
  43. pmc The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti
    Guowu Bian
    Department of Entomology and Genetics Program, Michigan State University, East Lansing, Michigan, United States of America
    PLoS Pathog 6:e1000833. 2010
    ..These results underscore the potential usefulness of Wolbachia-based control strategies for population replacement...
  44. ncbi The composite genome of the legume symbiont Sinorhizobium meliloti
    F Galibert
    UMR6061-CNRS, , , , F-35043 Rennes Cedex, France
    Science 293:668-72. 2001
    ..Genome sequence analysis indicates that all three elements contribute, in varying degrees, to symbiosis and reveals how this genome may have emerged during evolution...
  45. ncbi Plant peptides govern terminal differentiation of bacteria in symbiosis
    Willem Van de Velde
    Institut des Sciences du Vegetal, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette Cedex, France
    Science 327:1122-6. 2010
    ..Because NCRs resemble antimicrobial peptides, our findings reveal a previously unknown innovation of the host plant, which adopts effectors of the innate immune system for symbiosis to manipulate the cell fate of endosymbiotic bacteria.
  46. pmc Deep sequencing reveals exceptional diversity and modes of transmission for bacterial sponge symbionts
    Nicole S Webster
    Australian Institute of Marine Science, PMB 3, Townsville Mail Centre, Qld 4810, Australia
    Environ Microbiol 12:2070-82. 2010
    ..Thus, members of the rare seawater biosphere may serve as seed organisms for widely occurring symbiont populations in sponges and their host association might have evolved much more recently than previously thought...
  47. ncbi Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi
    Kohki Akiyama
    Division of Applied Biological Chemistry, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    Nature 435:824-7. 2005
    ..The natural strigolactones 5-deoxy-strigol, sorgolactone and strigol, and a synthetic analogue, GR24, induced extensive hyphal branching in germinating spores of the AM fungus Gigaspora margarita at very low concentrations...
  48. ncbi Biology bacteriocyte-associated endosymbionts of plant sap-sucking insects
    Paul Baumann
    Microbiology Section, University of California, Davis, California 95616, USA
    Annu Rev Microbiol 59:155-89. 2005
    ....
  49. ncbi A genomic view of the human-Bacteroides thetaiotaomicron symbiosis
    Jian Xu
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, MO 63110, USA
    Science 299:2074-6. 2003
    ..These and other expanded paralogous groups shed light on the molecular mechanisms underlying symbiotic host-bacterial relationships in our intestine...
  50. pmc The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode
    Jeremy Foster
    Molecular Parasitology Division, New England Biolabs, Beverly, Massachusetts, USA
    PLoS Biol 3:e121. 2005
    ..Analysis of this first sequenced endosymbiont genome from a filarial nematode provides insight into endosymbiont evolution and additionally provides new potential targets for elimination of cutaneous and lymphatic human filarial disease...
  51. pmc Immunity and other defenses in pea aphids, Acyrthosiphon pisum
    Nicole M Gerardo
    Department of Biology, Emory University, O Wayne Rollins Research Center, 1510 E, Clifton Road NE, Atlanta, GA 30322, USA
    Genome Biol 11:R21. 2010
    ....
  52. pmc Stars and symbiosis: microRNA- and microRNA*-mediated transcript cleavage involved in arbuscular mycorrhizal symbiosis
    Emanuel A Devers
    Max Planck Institute of Molecular Plant Physiology, 14476 Potsdam Golm, Germany
    Plant Physiol 156:1990-2010. 2011
    The majority of plants are able to form the arbuscular mycorrhizal (AM) symbiosis in association with AM fungi...
  53. pmc Host-bacterial symbiosis in health and disease
    Janet Chow
    Division of Biology, California Institute of Technology, Pasadena, California, USA
    Adv Immunol 107:243-74. 2010
    All animals live in symbiosis. Shaped by eons of co-evolution, host-bacterial associations have developed into prosperous relationships creating mechanisms for mutual benefits to both microbe and host...
  54. pmc Co-infection and localization of secondary symbionts in two whitefly species
    Marisa Skaljac
    Department of Entomology, Institute Plant Protection, Agricultural Research Organization, The Volcani Center, Bet Dagan, Israel
    BMC Microbiol 10:142. 2010
    ..We conducted a study to survey the distribution of whitefly species in Croatia, their infection status by secondary symbionts, and the spatial distribution of these symbionts in the developmental stages of the two whitefly species...
  55. ncbi Aphid protected from pathogen by endosymbiont
    Claire L Scarborough
    Natural Environment Research Council Centre for Population Biology, Division of Biology, Imperial College London, Silwood Park Campus, Ascot, Berks, SL5 7PY, UK
    Science 310:1781. 2005
    ....
  56. ncbi Wolbachia: more than just a bug in insects genitals
    Aggeliki Saridaki
    Department of Environmental and Natural Resources Management, University of Ioannina, Agrinio, Greece
    Curr Opin Microbiol 13:67-72. 2010
    ..The mutualistic relationship of Wolbachia strains with disease vectors remains among the top research priorities with new insights having an impact on putative anti-filarial strategies...
  57. pmc An interdependent metabolic patchwork in the nested symbiosis of mealybugs
    John P McCutcheon
    Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Curr Biol 21:1366-72. 2011
    ....
  58. ncbi Legumes symbioses: absence of Nod genes in photosynthetic bradyrhizobia
    Eric Giraud
    Institut de Recherche pour le Developpement, Centre de Coopération International en Recherche Agronomique pour le Développement, Institut National de la Recherche Agronomique, Universite Montpellier 2, France
    Science 316:1307-12. 2007
    ..and ORS278, that canonical nodABC genes and typical lipochito-oligosaccharidic Nod factors are not required for symbiosis in some legumes...
  59. ncbi Fungal lipochitooligosaccharide symbiotic signals in arbuscular mycorrhiza
    Fabienne Maillet
    Laboratoire des Interactions Plantes Microorganismes, UMR 441 2594 INRA CNRS, B P 52627, F 31326 Castanet Tolosan Cedex, France
    Nature 469:58-63. 2011
    ..It is the most widespread terrestrial plant symbiosis, improving plant uptake of water and mineral nutrients...
  60. ncbi Molecular interactions between bacterial symbionts and their hosts
    Colin Dale
    Department of Biology, University of Utah, Salt Lake City, UT 84112, USA
    Cell 126:453-65. 2006
    ..Furthermore, some symbionts use many of the same mechanisms as pathogens to infect hosts and evade immune responses. Here we discuss what is currently known about the interactions between bacterial symbionts and their hosts...
  61. ncbi The architecture of mutualistic networks minimizes competition and increases biodiversity
    Ugo Bastolla
    Centro de Biologia Molecular, Universidad Autonoma de Madrid CSIC, Madrid 28049, Spain
    Nature 458:1018-20. 2009
    ..Nested networks seem to occur in many biological and social contexts, suggesting that our results are relevant in a wide range of fields...
  62. pmc Variation in antiviral protection mediated by different Wolbachia strains in Drosophila simulans
    Sheree E Osborne
    School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
    PLoS Pathog 5:e1000656. 2009
    ..These results indicate that Wolbachia-mediated antiviral protection is not ubiquitous, a finding that is important for understanding the distribution of Wolbachia and virus in natural insect populations...
  63. ncbi Coral reefs: corals' adaptive response to climate change
    Andrew C Baker
    Marine Program, Wildlife Conservation Society, Bronx, New York 10460, USA
    Nature 430:741. 2004
    ..This adaptive shift in symbiont communities indicates that these devastated reefs could be more resistant to future thermal stress, resulting in significantly longer extinction times for surviving corals than had been previously assumed...
  64. ncbi Adaptation via symbiosis: recent spread of a Drosophila defensive symbiont
    John Jaenike
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Science 329:212-5. 2010
    ..These findings demonstrate the profound and potentially rapid effects of defensive symbionts, which are increasingly recognized as major players in the ecology of species interactions...
  65. pmc The endosymbiotic origin, diversification and fate of plastids
    Patrick J Keeling
    Botany Department, Canadian Institute for Advanced Research, University of British Columbia, 3529 6270 University Boulevard, Vancouver, BC, Canada V6T 1Z4
    Philos Trans R Soc Lond B Biol Sci 365:729-48. 2010
    ..The many twists and turns of plastid evolution each represent major evolutionary transitions, and each offers a glimpse into how genomes evolve and how cells integrate through gene transfers and protein trafficking...
  66. ncbi Establishing nitrogen-fixing symbiosis with legumes: how many rhizobium recipes?
    Catherine Masson-Boivin
    Laboratoire des Interactions Plantes Micro organismes LIPM, UMR CNRS INRA 2594 441, BP 52627, 31326 Castanet Tolosan Cedex, France
    Trends Microbiol 17:458-66. 2009
    ..that have achieved the environmentally essential function of fixing atmospheric nitrogen (N(2)) in symbiosis with legumes...
  67. pmc Cell biology of cnidarian-dinoflagellate symbiosis
    Simon K Davy
    School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand
    Microbiol Mol Biol Rev 76:229-61. 2012
    The symbiosis between cnidarians (e.g., corals or sea anemones) and intracellular dinoflagellate algae of the genus Symbiodinium is of immense ecological importance...
  68. ncbi Reciprocal rewards stabilize cooperation in the mycorrhizal symbiosis
    E Toby Kiers
    Institute of Ecological Science, Vrije Universiteit, 1081 HV Amsterdam, Netherlands
    Science 333:880-2. 2011
    ..Rather, the mutualism is evolutionarily stable because control is bidirectional, and partners offering the best rate of exchange are rewarded...
  69. pmc PGRP-LB is a maternally transmitted immune milk protein that influences symbiosis and parasitism in tsetse's offspring
    Jingwen Wang
    Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 109:10552-7. 2012
    ..We show that recPGRP-LB has antimicrobial and antitrypanosomal activities that may regulate symbiosis and impact immunity...
  70. ncbi The rules of engagement in the legume-rhizobial symbiosis
    Giles E D Oldroyd
    John Innes Center, Norwich Research Park, Norwich NR4 7UH, United Kingdom
    Annu Rev Genet 45:119-44. 2011
    ....
  71. pmc The transmission efficiency of tomato yellow leaf curl virus by the whitefly Bemisia tabaci is correlated with the presence of a specific symbiotic bacterium species
    Yuval Gottlieb
    Agricultural Research Organization, Institute of Plant Protection, Department of Entomology, Volcani Center, Bet Dagan 50250, Israel
    J Virol 84:9310-7. 2010
    ..The other symbionts from both biotypes do not seem to be involved in transmission of this virus...
  72. ncbi Arbuscule-containing and non-colonized cortical cells of mycorrhizal roots undergo extensive and specific reprogramming during arbuscular mycorrhizal development
    Nicole Gaude
    Max Planck Institute of Molecular Plant Physiology, Am Muhlenberg 1, 14476 Potsdam, Germany
    Plant J 69:510-28. 2012
    Most vascular plants form a mutualistic association with arbuscular mycorrhizal (AM) fungi, known as AM symbiosis. The development of AM symbiosis is an asynchronous process, and mycorrhizal roots therefore typically contain several ..
  73. ncbi Diversity and infection prevalence of endosymbionts in natural populations of the chestnut weevil: relevance of local climate and host plants
    Hirokazu Toju
    National Institute of Advanced Industrial Science and Technology AIST, Tsukuba 305 8566, Japan
    Mol Ecol 20:853-68. 2011
    ..These patterns are discussed in relation to potential host-endosymbiont co-evolution via local adaptation across geographical populations...
  74. pmc Evidence for metabolic provisioning by a common invertebrate endosymbiont, Wolbachia pipientis, during periods of nutritional stress
    Jeremy C Brownlie
    School of Biological Sciences, The University of Queensland, St Lucia, Queensland, Australia
    PLoS Pathog 5:e1000368. 2009
    ..These data suggest that Wolbachia may play a previously unrecognized role as nutritional mutualists in insects...
  75. pmc Evolution of symbiotic bacteria in the distal human intestine
    Jian Xu
    Center for Genome Sciences, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS Biol 5:e156. 2007
    ....
  76. pmc Functional convergence in reduced genomes of bacterial symbionts spanning 200 My of evolution
    John P McCutcheon
    Center for Insect Science, University of Arizona, Arizona, USA
    Genome Biol Evol 2:708-18. 2010
    ....
  77. pmc Membrane lipids of symbiotic algae are diagnostic of sensitivity to thermal bleaching in corals
    Dan Tchernov
    Environmental Biophysics and Molecular Ecology Program, Institute of Marine and Coastal Sciences, Rutgers, The State University of New Jersey, 71 Dudley Road, New Brunswick, NJ 08901, USA
    Proc Natl Acad Sci U S A 101:13531-5. 2004
    ..A clocked molecular phylogenetic analysis suggests that the evolutionary history of symbiotic algae in cnidarians selected for a reduced tolerance to elevated temperatures in the latter portion of the Cenozoic...
  78. ncbi Coral bleaching: thermal adaptation in reef coral symbionts
    Rob Rowan
    University of Guam Marine Laboratory, Mangilao, Guam 96923, USA
    Nature 430:742. 2004
    ..If other coral species can host these or similar Symbiodinium taxa, they might adapt to warmer habitats relatively easily...
  79. pmc Massive genomic decay in Serratia symbiotica, a recently evolved symbiont of aphids
    Gaelen R Burke
    Department of Ecology and Evolutionary Biology, The University of Arizona, USA
    Genome Biol Evol 3:195-208. 2011
    ..Analysis of mutational patterns showed that deletions are more common in neutral DNA. The S. symbiotica genome provides a rare opportunity to study genome evolution in a recently derived heritable symbiont...
  80. ncbi Cellular mechanisms of Cnidarian bleaching: stress causes the collapse of symbiosis
    Virginia M Weis
    Department of Zoology, Oregon State University, Corvallis, OR 97331, USA
    J Exp Biol 211:3059-66. 2008
    Cnidarian bleaching is a breakdown in the mutualistic symbiosis between host Cnidarians, such as reef building corals, and their unicellular photosynthetic dinoflagellate symbionts...
  81. ncbi Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    Seth Rakoff-Nahoum
    Howard Hughes Medical Institute and Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Cell 118:229-41. 2004
    ..These findings reveal a novel function of TLRs-control of intestinal epithelial homeostasis and protection from injury-and provide a new perspective on the evolution of host-microbial interactions...
  82. pmc Increased fitness of rice plants to abiotic stress via habitat adapted symbiosis: a strategy for mitigating impacts of climate change
    Regina S Redman
    Western Fisheries Research Center, United States Geological Survey, Seattle, Washington, United States of America
    PLoS ONE 6:e14823. 2011
    ..These findings indicate that rice plants can exhibit enhanced stress tolerance via symbiosis with Class 2 endophytes, and suggest that symbiotic technology may be useful in mitigating impacts of climate ..
  83. ncbi Facultative symbionts in aphids and the horizontal transfer of ecologically important traits
    Kerry M Oliver
    Department of Entomology, University of Georgia, Athens, GA 30602, USA
    Annu Rev Entomol 55:247-66. 2010
    ..Although transmitted maternally with high fidelity, facultative symbionts occasionally move horizontally within and between species, resulting in the instantaneous acquisition of ecologically important traits, such as parasitoid defense...
  84. pmc Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont
    Araceli Lamelas
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Valencia, Spain
    PLoS Genet 7:e1002357. 2011
    ..aphidicola BCc or taken over by S. symbiotica. In addition, there are several cases of metabolic complementation giving functional stability to the whole consortium and evolutionary preservation of the actors involved...
  85. ncbi Further insights into the strange role of bacterial endosymbionts in whitefly, Bemisia tabaci: comparison of secondary symbionts from biotypes B and Q in China
    D Chu
    High Tech Research Center, Shandong Academy of Agricultural Sciences, Key Laboratory for Genetic Improvement of Crop Animal and Poultry of Shandong Province, Jinan, China
    Bull Entomol Res 101:477-86. 2011
    ..Furthermore, within biotype Q, two distinct subgroups were identified which differ from each other in terms of their SS complement. We discuss these results in the light of the potentially influential factors and roles of the SS...
  86. ncbi Plastid evolution
    Sven B Gould
    School of Botany, University of Melbourne, Parkville VIC 3010, Australia
    Annu Rev Plant Biol 59:491-517. 2008
    ..We review the origins, integration, and functions of the different plastid types with special emphasis on their biochemical abilities, transfer of genes to the host, and the back supply of proteins to the endosymbiont...
  87. ncbi Functional genomic signatures of sponge bacteria reveal unique and shared features of symbiosis
    Torsten Thomas
    Centre for Marine Bio Innovation, The University of New South Wales, Sydney, Australia
    ISME J 4:1557-67. 2010
    ..These data provide new insight into the evolution of symbiotic diversity, microbial metabolism and host-microbe interactions in sponges...
  88. pmc Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer
    Samantha N McNulty
    Infectious Diseases Division, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    PLoS ONE 5:e11029. 2010
    ..The mechanisms behind this interdependence are not understood. Interestingly, a minority of filarial species examined to date are naturally Wolbachia-free...
  89. pmc Convergent evolution of metabolic roles in bacterial co-symbionts of insects
    John P McCutcheon
    Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 106:15394-9. 2009
    ....
  90. ncbi Diversity and occurrence of Burkholderia spp. in the natural environment
    Stéphane Compant
    Unité de Recherche Vignes et Vins de Champagne, UFR Sciences, Universite de Reims Champagne Ardenne, Reims, France
    FEMS Microbiol Rev 32:607-26. 2008
    ..with special emphasis on beneficial plant-Burkholderia interactions. A discussion of the potential for utilization of stable plant-Burkholderia spp. associations in the development of low-input cropping systems is also provided...
  91. ncbi Learning how to live together: genomic insights into prokaryote-animal symbioses
    Andres Moya
    Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de Valencia, Apartado de correos 22085 46071 València and CIBER de Epidemiología y Salud Pública, Spain
    Nat Rev Genet 9:218-29. 2008
    ..of the evolutionary process that starts with host invasion then progresses from facultative to obligate symbiosis and ends with replacement by, or coexistence with, new symbionts...
  92. ncbi The energetics of genome complexity
    Nick Lane
    Department of Genetics, Evolution and Environment, University College London, Gower Street, London W1E 6BT, UK
    Nature 467:929-34. 2010
    ..This vast leap in genomic capacity was strictly dependent on mitochondrial power, and prerequisite to eukaryote complexity: the key innovation en route to multicellular life...
  93. ncbi Genomic footprints of a cryptic plastid endosymbiosis in diatoms
    Ahmed Moustafa
    Interdisciplinary Program in Genetics, University of Iowa, Iowa City, IA 52242, USA
    Science 324:1724-6. 2009
    ..Chromalveolates appear to have recruited genes from the two major existing algal groups to forge a highly successful, species-rich protist lineage...
  94. ncbi The puzzle of plastid evolution
    John M Archibald
    The Canadian Institute for Advanced Research, Program in Integrated Microbial Biodiversity, Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, B3H 1X5, Canada
    Curr Biol 19:R81-8. 2009
    ..Consequently, new models of plastid evolution involving ancient secondary and tertiary endosymbioses are needed to explain the full spectrum of photosynthetic eukaryotes...
  95. ncbi Testing congruence in phylogenomic analysis
    Jessica W Leigh
    Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, Canada
    Syst Biol 57:104-15. 2008
    ..Investigating phylogenomic data sets for conflicting signals has the potential to both improve phylogenetic accuracy and inform our understanding of genome evolution...
  96. pmc The genome of the amoeba symbiont "Candidatus Amoebophilus asiaticus" reveals common mechanisms for host cell interaction among amoeba-associated bacteria
    Stephan Schmitz-Esser
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    J Bacteriol 192:1045-57. 2010
    ....
  97. pmc Origin and evolution of the mitochondrial proteome
    C G Kurland
    Department of Molecular Evolution, Evolutionary Biology Centre, University of Uppsala, Uppsala SE 752 36, Lund University, Lund SE 223 62, Sweden
    Microbiol Mol Biol Rev 64:786-820. 2000
    ..There are no indications of a specific alpha-proteobacterial origin to genes for glycolysis. In the absence of data to the contrary, it is assumed that the ancestral host cell was a heterotroph...
  98. ncbi Systemic analysis of the symbiotic function of Buchnera aphidicola, the primary endosymbiont of the pea aphid Acyrthosiphon pisum
    Lilia Brinza
    UMR203 BF2I, Biologie Fonctionnelle Insectes et Interactions, Universite de Lyon, INRA, INSA Lyon, IFR41, 20, avenue A Einstein, 69621 Villeurbanne, France
    C R Biol 332:1034-49. 2009
    ..aphidicola from the pea aphid Acyrthosiphon pisum, by analyzing their structural genomic properties, as well as their genetic and metabolic networks...
  99. pmc Trading molecules and tracking targets in symbiotic interactions
    Eric W Schmidt
    Department of Medicinal Chemistry, University of Utah, 30 South 2000 East, Salt Lake City, Utah 84112, USA
    Nat Chem Biol 4:466-73. 2008
    It is probable that nearly every natural product structure results from interactions between organisms. Symbiosis, a subset of inter-organism interactions involving closely associated partners, has recently provided new and interesting ..
  100. ncbi Complex diel cycles of gene expression in coral-algal symbiosis
    O Levy
    Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
    Science 331:175. 2011
    ..Conversely, central metabolism appears to be regulated by the hypoxia-inducible factor system in coral. These results reveal the complexity of endosymbiosis as well as the plasticity regulation downstream of the circadian clock...
  101. pmc Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Arizona Genomics Institute, University of Arizona, Tucson, AZ 85721 USA
    Proc Natl Acad Sci U S A 106:9063-8. 2009
    ..The genome is also littered with mobile DNA, including phage-derived genes, plasmids, and insertion-sequence elements, highlighting its dynamic nature and the continued role horizontal gene transfer plays in shaping it...

Research Grants65

  1. Quorum Sensing in Sinorhizobium meliloti
    Juan Gonzalez; Fiscal Year: 2009
    ..meliloti/alfalfa symbiosis. This study will provide a better understanding of the symbiotic/pathogenic relationships between prokaryotes ..
  2. Ca2+ and ROS Crosstalk Signaling in Cardiac Mitochondria
    Shey Shing Sheu; Fiscal Year: 2013
    ..g. cyclophilin D (CypD) knockout mice and mt-cpYFP transgenic mice) to elucidate the mechanisms of ROS and Ca2+ symbiosis with an unique emphasis on mitochondrial fission protein DLP1 and mitochondrial permeability transition (MPT)...
  3. Regulation of vitamin A metabolism during Schistosoma mansoni infection
    PNG LOKE; Fiscal Year: 2013
    ..mansoni infection. Perhaps the balance between pathogenesis and symbiosis is dependent on the nutritional status of infected individuals...
  4. Ecological triggers to exploit antibiotic and virulence factor regulation
    JASON MICHAEL CRAWFORD; Fiscal Year: 2013
    ..little about their ecological niches, Photorhabdus and Xenorhabdus species are at the center of a trilateral symbiosis with nematodes and insects that provides an ecological framework for laboratory investigation...
  5. Metabolic Engineering Studies of Extreme Thermoacidophily
    Robert M Kelly; Fiscal Year: 2010
    ..These organisms play an expanding role in global carbon cycling, nitrogen cycling, symbiosis and eukaryotic interactions...
  6. Identifying cellular and molecular interactions along the pathway to symbiosis
    Elizabeth A Vallen; Fiscal Year: 2012
    ..she will also utilize the techniques learned during this training period to address the cell biology of symbiosis in the naturally-symbiotic anemone, Aiptasia pallida...
  7. MOLECULAR GENETICS OF RHIZOBIUM NODULATION PLASMIDS
    Graham C Walker; Fiscal Year: 2013
    ..meliloti establishes the chronic intracellular infection that underlies its symbiosis and to use these findings to gain insights into the molecular strategies used by certain chronic intracellular ..
  8. Symbiosis of E. coli and the Intestinal Microbiota in a Mouse Model
    Tyrrell Conway; Fiscal Year: 2013
    ..Our research represents an unprecedented step forward in the effort to characterize the functional roles of individual microbes in the human microbiome. ..
  9. Cell-cell signaling, gene expression, and horizontal gene transfer in Bacillus
    Alan D Grossman; Fiscal Year: 2013
    ..Mobile genetic elements play significant roles in evolution, genome plasticity, symbiosis, pathogenesis, and the spread of antibiotic resistance...
  10. A Feeding Tube Model for Bacterial Cell-Cell Communication
    AMY HITCHCOCK CAMP; Fiscal Year: 2012
    ..multi- cellular"" behaviors such as antibiotic production, toxin secretion, motility, biofilm formation, symbiosis, and de- velopment...
  11. Control of Symbiotic Gene Expression in Sinorhizobium meliloti
    Sharon R Long; Fiscal Year: 2013
    ..Bacteria also use host molecules as signals. These signal exchanges are critical to pathogenesis and to symbiosis. We study Sinorhizobium meliloti, an alpha- proteobacterium, which establishes a beneficial nitrogen fixing ..
  12. Parvovirus-Cell Interactions
    David J Pintel; Fiscal Year: 2013
    ..AAV replication, our studies will help explain how sharing a viral E3 ubiquitin-ligase can help optimize the symbiosis of two co-infecting DNA viruses, and how a novel PKR- activating element within an mRNA of a DNA virus might ..
  13. The role of PhoP-PhoQ in an insect-bacterial symbiosis
    Colin Dale; Fiscal Year: 2013
    ..tsetse fly endosymbiont, Sodalis glossinidius, which controls the expression of a number of essential symbiosis determinants in vivo...
  14. Genomic and metabolomic foundations of human-microbial symbiosis in the gut
    JEFFREY IVAN GORDON; Fiscal Year: 2013
    ..M. smithii, and E. rectale/E. eligens. These studies should provide new approaches for monitoring and manipulating the functions of the microbiota to promote human health. ..
  15. Sodalis glossinidius iron acquisition
    LAURA JANE RUNYEN-JANECKY; Fiscal Year: 2012
    ..Studying the tsetse fly-Sodalis symbiosis will have significance to public health...
  16. Developing Hydra as a Model Organism for Viral Symbioses
    Juris A Grasis; Fiscal Year: 2012
    ..gene knockdown, to determine which genes are vital in either limiting viral pathogenesis or promoting viral symbiosis. PUBLIC HEALTH RELEVANCE: Viruses are the most abundant entities on Earth and all cellular organisms have ..
  17. Regulatory network of a conserved polar factor in Sinorhizobium meliloti
    JOSEPH CHIUNG CHU CHEN; Fiscal Year: 2013
    ..in the alpha- proteobacterium Sinorhizobium meliloti, which infects the roots of legume plants to form symbiosis. Specifically, the PodJ1 protein (SMc02230) localizes to the newer cell pole and deletion of the podJ1 gene ..
  18. Functional analysis of a symbiotic polydnavirus
    Gaelen R Burke; Fiscal Year: 2013
    ..provided by applicant): Many microorganisms have evolved associations with metazoans that range from beneficial symbiosis to pathogenic...
  19. Anaplasma phagocytophilum induce Ixodes scapularis antifreeze glycoprotein gene e
    Girish Neelakanta; Fiscal Year: 2012
    ..scapularis. These data define a molecular basis for symbiosis between A. phagocytophilum and I. scapularis. The mechanism by which A...
  20. Analysis of quorum-signaling crosstalk within the squid-vibrio symbiosis
    TIMOTHY MIYASHIRO; Fiscal Year: 2012
    ..chronic infections of host epithelial tissue by beneficial microbes, I have been studying the mutualistic symbiosis between the marine bacterium Vibrio fischeri and the Hawaiian squid Euprymna scolopes...
  21. REQUIREMENTS FOR BACTERIAL COLONIZATION OF ANIMAL TISSUE
    Karen L Visick; Fiscal Year: 2013
    ..One of these is our model, the symbiosis between Vibrio fischeri and its squid host, which has revealed a clear correlation between biofilms in lab and ..
  22. 2010 Cell and Molecular Fungal Biology; Gordon Research Conference
    John W Taylor; Fiscal Year: 2010
    ..g., systems biology, small RNA, population genomics, with topics of enduring significance, e.g., pathogenesis, symbiosis, membrane trafficking, and cytoskeleton and motors...
  23. Analysis of quorum-signaling crosstalk within the squid-vibrio symbiosis
    TIMOTHY MIYASHIRO; Fiscal Year: 2013
    ..chronic infections of host epithelial tissue by beneficial microbes, I have been studying the mutualistic symbiosis between the marine bacterium Vibrio fischeri and the Hawaiian squid Euprymna scolopes...
  24. Regulated Assembly of Subcellular Structures in alpha-Proteobacteria
    JOSEPH CHIUNG CHU CHEN; Fiscal Year: 2010
    ..are conserved in Sinorhizobium meliloti, a related bacterium that induces nodule formation in plant roots during symbiosis. However, S. meliloti cells are morphologically symmetric compared to C. crescentus...
  25. Genetics and biosynthesis of an O antigen essential for symbiosis
    KENNETH D NOEL; Fiscal Year: 2010
    ..The importance of its O-antigen in the symbiosis with Phaseolus vulgaris (bean) has been established, the structure of the entire LPS is almost completely solved,..
  26. Natural Products from Under-explored Microorganisms
    Ben Shen; Fiscal Year: 2012
    ..The criteria for strain selection are: (i) the uniqueness and richness of biodiversity, (ii) symbiosis with traditional Chinese medicinal plants, (iii) morphological and taxonomical distinctiveness, and (iv) bias ..
  27. Symbiosis and Immunity in the Tsetse Fly
    Brian L Weiss; Fiscal Year: 2013
    ..Furthermore, basic concepts related to the genetics that underlie symbiont-induced immunity in tsetse may be of fundamental importance to mammalian immunology. ..
  28. Protection from Mucosal Pathology by Gut Microbiota during Colitis
    Sarkis K Mazmanian; Fiscal Year: 2013
    ..Our laboratory has described a leading model system for studying beneficial host-bacterial symbiosis. Bacteroides fragilis, a common member of the human microbiome, ameliorates gut inflammation and treats ..
  29. 4th ASM Conference on Cell-Cell Communication in Bacteria
    Gary M Dunny; Fiscal Year: 2011
    ..communication in bacterial development and antibiotic production;host-microbe signaling and pathogenesis;symbiosis, mutualism, and microbe-microbe communication;ecology and evolution;advancements in the technological tool-kit ..
  30. The protein nutrition of the symbiotic system between /Drosophila/and its gut mic
    ANGELA E SEARLE; Fiscal Year: 2013
    ..The basis of this proposal is that the nutritional physiology and symbiosis of animals are interdependent, such that animal protein nutrition can only be understood fully when considered ..
  31. 2012 Cellular and Molecular Fungal Biology Gordon Research Conference
    Judith G Berman; Fiscal Year: 2012
    ..and core topics to this conference such as systems biology, population and evolutionary genomics, pathogenesis, symbiosis, cell biology and gene expression including RNA control...
  32. Significance of Bacteroides fragilis polysaccharide phase variation
    Laurie E Comstock; Fiscal Year: 2013
    ..analyze polysaccharide expression profiles from bacteria isolated from different environments representing both symbiosis and disease. For these analyses, we will obtain human fecal and clinical samples containing B...
  33. Flagellin regulation by Vibrio fischeri during colonization and presistence
    TIMOTHY MIYASHIRO; Fiscal Year: 2010
    ..By taking advantage of the natural symbiosis between the Hawaiian squid Euprymna scolopes and its bacterial symbiont Vibrio fischeri, the proposed ..
  34. Vibrio fischeri as a model of bacterial colonization
    Edward G Ruby; Fiscal Year: 2013
    ..One such model is the binary symbiosis between the bioluminescent Gram-negative bacterium, Vibrio fischeri, and its squid host, Euprymna scolopes...
  35. The genetic determinants of symbiotic host-microbial interaction in the human gut
    Andrew Goodman; Fiscal Year: 2009
    ..Identifying these genetic determinants of symbiosis in single- and multi-species gut microbial communities will facilitate efforts to manipulate these communities ..
  36. VIBRIO VIRULENCE DETERMINANTS IN A BENIGN COLONIZATION
    Edward G Ruby; Fiscal Year: 2013
    ..One such model system is the light- organ symbiosis between the bioluminescent bacterium, Vibrio fischeri, and its squid host, Euprymna scolopes...
  37. The effect of coinheritance on host-symbiont coevolution
    Michael J Wade; Fiscal Year: 2013
    ..determines whether a host-symbiont association evolves toward enhanced virulence or toward benign mutualistic symbiosis. When applied to nuclear and mitochondrial gene combinations, we successfully predicted that the frequency of ..
  38. Algorithmically-Tuned Protein Families, Rule_Base and Characterized Proteins
    Daniel H Haft; Fiscal Year: 2010
    ..communities present in or on the human body holds promise for explaining the dynamic basis of host-microbiome symbiosis and the contribution of these communities (the human microbiome) to health and disease...
  39. Resistance and resiliency in a natural host-microbe symbiosis
    Edward G Ruby; Fiscal Year: 2013
    ..One such model system is the light-organ symbiosis between a bioluminescent marine bacterium and its squid host...
  40. Elucidation of colonization and virulence through a novel comparative approach
    CHERYL WHISTLER; Fiscal Year: 2009
    ..regulators conserved throughout the genus including the symbiotic bacterium, Vibrio fischeri, 2) GacA regulates symbiosis factors and host-colonization in V...
  41. Biosynthesis and Physiology of Vitamin B12 in Prokaryotes
    MICHIKO TAGA; Fiscal Year: 2009
    ..The bluB mutant of S. meliloti is severely impaired in establishing a nitrogen-fixing symbiosis with its legume host, alfalfa...
  42. Investigation of microbial factors required for integrated functions of the Droso
    Peter D Newell; Fiscal Year: 2013
    ..To elucidate the mechanistic basis of symbiosis, the final aim will identify specific genes and metabolic pathways required for the persistence of a prominent ..
  43. Regulation of the multiple polysaccharides of Bacteroides fragilis
    Laurie E Comstock; Fiscal Year: 2010
    ..fragilis is regulated to better appreciate their contributions to symbiosis and virulence...
  44. Pathogenesis to cooperation in the microbiome of a soil amoeba
    SUSANNE DISALVO; Fiscal Year: 2013
    ..in-depth analysis of the molecular mechanisms involved in the amoeba-bacterial interface, thereby allowing for greater resolution of the dynamic causes and consequences of trans- kingdom interactions along the wider symbiosis continuum.
  45. REGULATION OF NODULATION GENES IN RHIZOBIUM MELILOTI
    Sharon Long; Fiscal Year: 2002
    ..concerns the regulation of gene expression in a prokaryote, Rhizobium meliloti, that infects and establishes symbiosis with eukaryotic plant hosts such as alfalfa (Medicago sativa)...
  46. Vector Population Modification Using Wolbachia Symbionts
    Stephen Dobson; Fiscal Year: 2006
    ..implementation, and evaluation, aims will include better defining the infection dynamics of the Culex/Wolbachia symbiosis (e.g...
  47. Adaptive evolution of pathogenesis towards symbiosis
    Serap Aksoy; Fiscal Year: 2009
    ..have been sequenced, which will facilitate in observing symbiosis at the genetic and functional level...
  48. TRIFOLIIN A & ITS RECEPTORS ON RHIZOBIUM TRIFOLII
    Frank Dazzo; Fiscal Year: 1990
    ..trifolii is a gram-negative bacterium which specifically infects clover root hairs and forms a root nodule symbiosis which fixes atmospheric nitrogen into ammonia...
  49. Genome Evolution, Innovation and Adaptation in the Apicomplexa
    Jessica C Kissinger; Fiscal Year: 2010
    ..However, apicomplexan parasites have had an eventful evolutionary history involving endo-symbiosis of a red alga and numerous gene transfers from the alga and other bacteria...
  50. OXYGEN REGULATION OF SYMBIOTIC GENES IN RHIZOBIUM
    Gary Ditta; Fiscal Year: 1993
    ..goal of our research is to try and understand how the bacterium Rhizobium meliloti establishes a nitrogen-fixing symbiosis with its legume host alfalfa. During symbiosis, a complex developmental program governs the progression of R...
  51. STRUCTURE-FUNCTION RELATIONSHIPS OF LECTINS
    MARILYNN ETZLER; Fiscal Year: 2003
    ..and have been found to play a role in the oligosaccharide recognition events that initiate the nitrogen-fixing symbiosis that occurs between rhizobia and legumes...
  52. Identifying human genes required by tick-borne pathogens
    Ulrike Munderloh; Fiscal Year: 2007
    ..This proposal will address the symbiosis of parasite and host at the molecular level using human cells and a human pathogen...
  53. 6th International Society for Symbiosis Congress
    Heidi Goodrich Blair; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): The International Symbiosis Society (ISS) Congress, held every third year, is a forum to communicate recent advances in the field of beneficial host-microbe interactions...
  54. Investigation of iron acquisition genes in Sodalis glossinidius using new tools.
    Laura Runyen Janecky; Fiscal Year: 2009
    ..PUBLIC HEALTH RELEVANCE: Studying the tsetse fly-Sodalis symbiosis will have significance to public health because the presence of Sodalis in the tsetse fly may increase tsetse-..
  55. AUTO SPECTRAL TOPOGRAPHY FOR CERVICAL TISSUE SCREENING
    Jeremy Lerner; Fiscal Year: 1999
    ..AutoCerSpex is a logical symbiosis of techniques known to be effective and will greatly enhance the scope of standard Pap tests...
  56. HOST RECOGNITION AND INFECTION OF SOYBEAN BY RHIZOBIUM
    Gary Stacey; Fiscal Year: 1990
    ..research is to elucidate the molecular mechanism of host recognition in the Bardyrhizobium japonicum-soybean symbiosis. It is hoped that this research will add to the general knowledge of the mechanism of specific cell-cell ..
  57. PATHOGENESIS OF PEDIATRIC HIV INFECTION
    William Borkowsky; Fiscal Year: 2000
    ..occurs, a spectrum of clinical outcomes is seen, from rapid disease progression on one end to a process of symbiosis on the other...
  58. Intracellular Epithelial Sensors of Intestinal Bacteria
    Daniel Podolsky; Fiscal Year: 2009
    ..broad hypotheses: 1) Nod proteins monitor for the presence of intracellular bacteria 2) That commensalism and symbiosis reflects the nature of the epithelial response to the bacteria as much as the intrinsic invasive properties of ..
  59. Signal transduction through RscS in symbiosis
    KATHERINE GESZVAIN; Fiscal Year: 2007
    ..a model system to study the signal exchange between a prokaryote and a eukaryote during establishment of symbiosis. The hybrid sensor kinase RscS of V. fischeri is required for the initiation of symbiosis...
  60. 2nd ASM Conference on Beneficial Microbes - Host-Microbe Interactions in Health a
    MARGARET MC FALL NGAI; Fiscal Year: 2008
    ..The aim of this conference is to provide a forum for discussion and exchange of ideas, and for the development of new approaches and a conceptual synthesis. [unreadable] [unreadable] [unreadable]..
  61. Gene expression in commensal tsetse symbionts
    Brian Weiss; Fiscal Year: 2007
    ..These 'paratransgenic' flies and their offspring will then be monitored for changes in fitness, stability of recombinant protein expression and trypanosome vectorial capacity. ..