mouth floor

Summary

Top Publications

  1. ncbi Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock
    Vanina S Kanoore Edul
    Servicio de Terapia Intensiva, Sanatorio Otamendi y Miroli, Buenos Aires, Argentina
    Crit Care Med 40:1443-8. 2012
  2. ncbi Sublingual capnometry tracks microcirculatory changes in septic patients
    Jacques Creteur
    Department of Intensive Care, Erasme University Hospital, Route de Lennik 808, 1070, Brussels, Belgium
    Intensive Care Med 32:516-23. 2006
  3. pmc Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis
    J G G Dobbe
    Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Biol Eng Comput 46:659-70. 2008
  4. ncbi Changes in the sublingual microcirculation and endothelial adhesion molecules during the course of severe meningococcal disease treated in the paediatric intensive care unit
    Fauzia Paize
    Institute of Child Health, University of Liverpool, Alder Hey Children s NHS Foundation Trust, Liverpool, L12 2AP, UK
    Intensive Care Med 38:863-71. 2012
  5. ncbi Both passive leg raising and intravascular volume expansion improve sublingual microcirculatory perfusion in severe sepsis and septic shock patients
    Julien Pottecher
    Unité EA 3509, Departement d Anesthesie Reanimation, Centre Hospitalier Universitaire de Bicetre, Assistance Publique Hopitaux de Paris, Université Paris 11, 78 rue du General Leclerc, 94275, Le Kremlin Bicetre Cedex, France
    Intensive Care Med 36:1867-74. 2010
  6. ncbi Hypertonic fluid administration in patients with septic shock: a prospective randomized controlled pilot study
    Frank M P van Haren
    Intensive Care Department, The Canberra Hospital, Canberra, Australia
    Shock 37:268-75. 2012
  7. pmc Bedside sublingual video imaging of microcirculation in assessing bacterial infection in cirrhosis
    Muhammad Y Sheikh
    Division of Gastroenterology and Hepatology, University of California San Francisco Fresno Medical Education Program, Community Regional Medical Center, 2823 Fresno Street, 1st Floor, Endoscopy Suite, Fresno, CA 93721, USA
    Dig Dis Sci 54:2706-11. 2009
  8. ncbi Microvascular alterations in patients with acute severe heart failure and cardiogenic shock
    Daniel De Backer
    Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Brussels, Belgium
    Am Heart J 147:91-9. 2004
  9. ncbi Persistent villi hypoperfusion explains intramucosal acidosis in sheep endotoxemia
    Arnaldo Dubin
    Facultad de Ciencias Medicas, Universidad Nacional de La Plata, La Plata, Argentina
    Crit Care Med 36:535-42. 2008
  10. ncbi Comparative permeability of various chemical markers through human vaginal and buccal mucosa as well as porcine buccal and mouth floor mucosa
    Armorel D van Eyk
    Department of Pharmacology, Faculty of Health Sciences, University of Stellenbosch, Private Bag X1, Tygerberg 7505, South Africa
    Arch Oral Biol 49:387-92. 2004

Research Grants

  1. ORAL MUCOSA MICROBIOTA IN HEALTH, CANCER & MUCOSITIS
    Donna Mager; Fiscal Year: 2004
  2. Optical Imaging of Retinal Blood Circulation
    LEONARD WINCHESTER; Fiscal Year: 2005
  3. Raman Determination of Ligament Tension
    LEONARD WINCHESTER; Fiscal Year: 2006
  4. Realtime Monitoring of Sublingual Blood Velocity
    LEONARD WINCHESTER; Fiscal Year: 2006
  5. Noninvasive Methemoglobin Monitoring Technology
    LEONARD WINCHESTER; Fiscal Year: 2007
  6. OPTICAL DETECTION OF INTRAVENOUS INFILTRATION
    LEONARD WINCHESTER; Fiscal Year: 2008

Detail Information

Publications218 found, 100 shown here

  1. ncbi Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock
    Vanina S Kanoore Edul
    Servicio de Terapia Intensiva, Sanatorio Otamendi y Miroli, Buenos Aires, Argentina
    Crit Care Med 40:1443-8. 2012
    ..Our hypotheses were that 1) hyperdynamic blood flow is absent in septic shock; 2) nonsurvivors show more severe alterations than survivors; and 3) quantitative and semiquantitative microcirculatory parameters have a similar performance...
  2. ncbi Sublingual capnometry tracks microcirculatory changes in septic patients
    Jacques Creteur
    Department of Intensive Care, Erasme University Hospital, Route de Lennik 808, 1070, Brussels, Belgium
    Intensive Care Med 32:516-23. 2006
    ..To test the hypothesis that microcirculatory blood flow is the main determinant of sublingual carbon dioxide pressure in patients with septic shock...
  3. pmc Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis
    J G G Dobbe
    Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Biol Eng Comput 46:659-70. 2008
    ..RBC velocity was reduced by 70% during the first 10 s of cardiac luxation. The present method has been shown to be fast and accurate and provides increased insight into the functional properties of the microcirculation...
  4. ncbi Changes in the sublingual microcirculation and endothelial adhesion molecules during the course of severe meningococcal disease treated in the paediatric intensive care unit
    Fauzia Paize
    Institute of Child Health, University of Liverpool, Alder Hey Children s NHS Foundation Trust, Liverpool, L12 2AP, UK
    Intensive Care Med 38:863-71. 2012
    ..We studied sublingual microcirculatory disturbances in children with meningococcal disease (MCD) and simultaneously measured plasma levels of adhesion molecules...
  5. ncbi Both passive leg raising and intravascular volume expansion improve sublingual microcirculatory perfusion in severe sepsis and septic shock patients
    Julien Pottecher
    Unité EA 3509, Departement d Anesthesie Reanimation, Centre Hospitalier Universitaire de Bicetre, Assistance Publique Hopitaux de Paris, Université Paris 11, 78 rue du General Leclerc, 94275, Le Kremlin Bicetre Cedex, France
    Intensive Care Med 36:1867-74. 2010
    ..To assess sublingual microcirculatory changes following passive leg raising (PLR) and volume expansion (VE) in septic patients...
  6. ncbi Hypertonic fluid administration in patients with septic shock: a prospective randomized controlled pilot study
    Frank M P van Haren
    Intensive Care Department, The Canberra Hospital, Canberra, Australia
    Shock 37:268-75. 2012
    ..Independent of changes in preload or afterload, hypertonic fluid administration improved the cardiac contractility and vascular tone compared with isotonic fluid. The need for ongoing fluid resuscitation was also reduced...
  7. pmc Bedside sublingual video imaging of microcirculation in assessing bacterial infection in cirrhosis
    Muhammad Y Sheikh
    Division of Gastroenterology and Hepatology, University of California San Francisco Fresno Medical Education Program, Community Regional Medical Center, 2823 Fresno Street, 1st Floor, Endoscopy Suite, Fresno, CA 93721, USA
    Dig Dis Sci 54:2706-11. 2009
    ..5 was found to have highest sensitivity (100%) and specificity (100%) for infection in decompensated cirrhosis. SDF imaging of sublingual microcirculation can be a useful bedside diagnostic tool to assess bacterial infection in cirrhosis...
  8. ncbi Microvascular alterations in patients with acute severe heart failure and cardiogenic shock
    Daniel De Backer
    Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Brussels, Belgium
    Am Heart J 147:91-9. 2004
    ..We hypothesized that microvascular blood flow alterations are present in patients with severe heart failure and cardiogenic shock...
  9. ncbi Persistent villi hypoperfusion explains intramucosal acidosis in sheep endotoxemia
    Arnaldo Dubin
    Facultad de Ciencias Medicas, Universidad Nacional de La Plata, La Plata, Argentina
    Crit Care Med 36:535-42. 2008
    ..To test the hypothesis that persistent villi hypoperfusion explains intramucosal acidosis after endotoxemic shock resuscitation...
  10. ncbi Comparative permeability of various chemical markers through human vaginal and buccal mucosa as well as porcine buccal and mouth floor mucosa
    Armorel D van Eyk
    Department of Pharmacology, Faculty of Health Sciences, University of Stellenbosch, Private Bag X1, Tygerberg 7505, South Africa
    Arch Oral Biol 49:387-92. 2004
    ..is compared with the more recent human vaginal model and both these are in turn further compared to porcine mouth floor mucosa...
  11. ncbi Point-of-care assessment of microvascular blood flow in critically ill patients
    Ryan C Arnold
    Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, One Cooper Plaza, Camden, NJ 08103, USA
    Intensive Care Med 35:1761-6. 2009
    ..We hypothesized that a real-time point-of-care (POC) determination of the microcirculatory flow index (MFI), an established metric for assessing microcirculatory perfusion, agrees well with the conventional off-line analysis...
  12. ncbi Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
    Yasser Sakr
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
    Crit Care Med 32:1825-31. 2004
    ..To characterize the time course of microcirculatory alterations and their relation to outcome in patients with septic shock...
  13. ncbi The heterogeneity of the microcirculation in critical illness
    Eva Klijn
    Department of Intensive Care, Erasmus MC University Medical Center, PO Box 2040, Room H 627, 3000 CA Rotterdam, The Netherlands
    Clin Chest Med 29:643-54, viii. 2008
    ..The morphology of microvascular beds that have been visualized during surgery and intensive care at the bedside are also described, including those of the brain, sublingual region, skin, intestine, and eyes...
  14. pmc Reconstruction of the anterior floor of the mouth using a peroneal perforator free flap. A case report
    A Baj
    Department of Maxillo Facial Surgery, Istituto Ortopedico Galeazzi, University of Milan, Via Riccardo Galeazzi 4, Milan, Italy
    Acta Otorhinolaryngol Ital 30:47-51. 2010
    ....
  15. ncbi Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival
    Stephen Trzeciak
    Division of Cardiovascular Disease and Critical Care Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
    Ann Emerg Med 49:88-98, 98.e1-2. 2007
    ....
  16. pmc Mechanisms of critical illness--classifying microcirculatory flow abnormalities in distributive shock
    Paul W G Elbers
    Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 10:221. 2006
    ..It is hoped that this classification system will help in the identification of mechanisms underlying these abnormalities and indicate optimal therapies for resuscitating septic and other types of distributive shock...
  17. ncbi Comparison of 6% hydroxyethyl starch 130/0.4 and saline solution for resuscitation of the microcirculation during the early goal-directed therapy of septic patients
    Arnaldo Dubin
    Servicio de Terapia Intensiva, Sanatorio Otamendi y Miroli, Azcuenaga 870, Buenos Aires C1115AAB, Argentina
    J Crit Care 25:659.e1-8. 2010
    ..The aim of this study was to show that 6% hydroxyethyl starch (HES) 130/0.4 achieves a better resuscitation of the microcirculation than normal saline solution (SS), during early goal-directed therapy (EGDT) in septic patients...
  18. ncbi Effects of hydrocortisone on microcirculatory alterations in patients with septic shock
    Gustavo Luiz Büchele
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Belgium
    Crit Care Med 37:1341-7. 2009
    ..To evaluate the effects of hydrocortisone on microcirculatory blood flow alterations in patients with septic shock...
  19. ncbi Effect of vasopressin on sublingual microcirculation in a patient with distributive shock
    Marc J Dubois
    Department of Intensive Care Medicine, Erasme Hospital, Route de Lennik 808, 1070, Brussels, Belgium
    Intensive Care Med 29:1020-3. 2003
    ..To assess the sublingual microcirculation in a patient during vasopressin administration for a distributive shock after cardiopulmonary bypass...
  20. ncbi [Mouth floor and mobile tongue epidermoid carcinomas thickness: prognostic value]
    M El-Okeily
    Service de chirurgie maxillofaciale, Hopital Pellegrin, Centre Hospitalier Universitaire de Bordeaux, Place Amelie Raba Leon, 33076 Bordeaux Cedex, France
    Rev Stomatol Chir Maxillofac 109:81-5. 2008
    ..The aim of our retrospective study was to assess the prognostic value of tumor thickness in oral epidermoid carcinoma...
  21. ncbi Sublingual microcirculatory flow is impaired by the vasopressin-analogue terlipressin in a patient with catecholamine-resistant septic shock
    E C Boerma
    Department of Physiology, Academic Medical Centre, University of Amsterdam, The Netherlands
    Acta Anaesthesiol Scand 49:1387-90. 2005
    ..It indicates that much caution should be taken when considering such potent vasoconstrictor when correcting blood pressure during shock...
  22. ncbi Unilateral subcutaneous pedicled nasolabial island flap for anterior mouth floor reconstruction
    Nikolaos Lazaridis
    Department of Oral and Maxillofacial Sugery, G Papanikolaou General Hospital, Thessaloniki, Greece
    J Oral Maxillofac Surg 61:182-90. 2003
    ..This article describes the successful use of unilateral subcutaneous pedicled flaps in the reconstruction of defects of the anterior floor of the mouth by raising the flaps as skin islands, relying on a pedicle of subcutaneous tissue...
  23. ncbi Microcirculatory imaging in cardiac anesthesia: ketanserin reduces blood pressure but not perfused capillary density
    Paul W G Elbers
    Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Cardiothorac Vasc Anesth 23:95-101. 2009
    ..In order to introduce SDF imaging in cardiac anesthesia, the authors set out to directly observe the sublingual microcirculation in this setting...
  24. ncbi The effects of intra-aortic balloon pump support on macrocirculation and tissue microcirculation in patients with cardiogenic shock
    Corstiaan A den Uil
    Thoraxcenter, Departments of Cardiology and Intensive Care Medicine, Erasmus Medical Center, s Gravendijkwal 230, Rotterdam NL 3015 CE, The Netherlands
    Cardiology 114:42-6. 2009
    ..It was the aim of this study to evaluate the effects of intra-aortic balloon pump (IABP) counterpulsation on sublingual microcirculation as a model for tissue perfusion...
  25. ncbi The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects
    Daniel De Backer
    Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Belgium
    Crit Care Med 34:403-8. 2006
    ..To evaluate the effects of dobutamine on microcirculatory blood flow alterations in patients with septic shock...
  26. ncbi Effects of nitroglycerin on sublingual microcirculatory blood flow in patients with severe sepsis/septic shock after a strict resuscitation protocol: a double-blind randomized placebo controlled trial
    E Christiaan Boerma
    Department of Translational Physiology ECB, CI, Academic Medical Centre, Amsterdam, The Netherlands
    Crit Care Med 38:93-100. 2010
    ..We tested this concept after fulfillment of preset systemic hemodynamic resuscitation end points in the early phase of sepsis...
  27. pmc Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study
    Arnaldo Dubin
    Servicio de Terapia Intensiva, Sanatorio Otamendi y Miroli, Buenos Aires C1115AAB, Argentina
    Crit Care 13:R92. 2009
    ..Our goal was to assess the effects of titration of a norepinephrine infusion to increasing levels of mean arterial pressure (MAP) on sublingual microcirculation...
  28. ncbi Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis
    E Christiaan Boerma
    Department of Physiology, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care Med 35:1055-60. 2007
    ..To evaluate the relation between sublingual and intestinal microcirculatory alterations in patients with abdominal sepsis...
  29. ncbi [Apoptosis of human carcinoma of mouth floor KB cells and multidrug resistant KBv200 cells induced by azide methyl anthraquinone derivative]
    Yan Ding
    Cancer Center, Sun Yat Sen University, Guangzhou 510060, China
    Yao Xue Xue Bao 40:22-6. 2005
    ..To determine the effects of azide methyl anthraquinone derivative (AMAD) on growth inhibition and inducing apoptosis of multidrug resistant (MDR) KBv200 cells and parental drug-sensitive KB cells...
  30. ncbi Detection of HPV in mouth floor squamous cell carcinoma and its correlation with clinicopathologic variables, risk factors and survival
    L E Simonato
    Post Graduation Program, School of Dentistry, UNESP Sao Paulo State University, Aracatuba, Sao Paulo, Brazil
    J Oral Pathol Med 37:593-8. 2008
    ..The purpose of this study was to investigate the prevalence of HPV in mouth floor squamous cell carcinoma and correlate it with clinicopathologic variables, risk factors and survival...
  31. ncbi Microvascular blood flow is altered in patients with sepsis
    Daniel De Backer
    Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Belgium
    Am J Respir Crit Care Med 166:98-104. 2002
    ..The topical application of acetylcholine totally reversed these alterations. In conclusion, microvascular blood flow alterations are frequent in patients with sepsis and are more severe in patients with a worse outcome...
  32. ncbi Effects of drotrecogin alfa activated on microcirculatory alterations in patients with severe sepsis
    Daniel De Backer
    Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Brussels, Belgium
    Crit Care Med 34:1918-24. 2006
    ..We investigated whether DAA can influence microcirculatory alterations in patients with severe sepsis...
  33. ncbi Tremor of the mouth floor and anti-glutamic acid decarboxylase autoantibodies
    M Vianello
    Department of Neurological and Psychiatric Sciences Second Clinic, University of Padua, Padua, Italy
    Eur J Neurol 10:513-4. 2003
    ..The correlation between the tremor and antibody positivity is unclear although an alteration of the gabaergic system mediated by the antibodies may be hypothesised on the basis of an inflammatory CSF profile...
  34. ncbi Microvascular response to red blood cell transfusion in patients with severe sepsis
    Yasser Sakr
    Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Brussels, Belgium
    Crit Care Med 35:1639-44. 2007
    ..The effects of red blood cell transfusions on microvascular perfusion are not well defined. We investigated the effects of red blood cell transfusion on sublingual microvascular perfusion in patients with sepsis...
  35. ncbi Evaluation of sublingual and gut mucosal microcirculation in sepsis: a quantitative analysis
    Colin L Verdant
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Crit Care Med 37:2875-81. 2009
    ..To determine the relationship between sublingual and intestinal mucosal microcirculatory perfusion...
  36. ncbi Short-term effects of terlipressin bolus infusion on sublingual microcirculatory blood flow during septic shock
    Andrea Morelli
    Department of Anesthesiology and Intensive Care, University of Rome, Sapienza, Viale del Policlinico 155, 00161 Rome, Italy
    Intensive Care Med 37:963-9. 2011
    ..The objective of the present study was, therefore, to elucidate the effects of a single terlipressin bolus dose of 0.5 mg on microcirculatory perfusion in patients with catecholamine-dependent septic shock...
  37. pmc Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study
    Andrea Morelli
    Department of Anesthesiology and Intensive Care, University of Rome, La Sapienza, Viale del Policlinico 155, Rome 00161, Italy
    Crit Care 14:R232. 2010
    ..e. dobutamine). The primary end point was a difference of ≥ 20% in the microvascular flow index of small vessels (MFIs) among groups...
  38. ncbi Microcirculatory parameters after isotonic and hypertonic colloidal fluid resuscitation in acute hemorrhagic shock
    Stephan Maier
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    J Trauma 66:337-45. 2009
    ..We investigated sublingual mucosal microcirculatory parameters during hemorrhage and after fluid resuscitation with gelatin, hydroxyethyl starch, or hypertonic saline and hydroxyethyl starch in pigs...
  39. ncbi Effects of phenylephrine on the sublingual microcirculation during cardiopulmonary bypass
    S Maier
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Br J Anaesth 102:485-91. 2009
    ....
  40. ncbi Effects of fluids on microvascular perfusion in patients with severe sepsis
    Gustavo Ospina-Tascon
    Department of Intensive Care, Erasme University Hospital, Universite Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium
    Intensive Care Med 36:949-55. 2010
    ..To evaluate the effects of fluid administration on microcirculatory alterations in sepsis...
  41. ncbi Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications
    Shaman Jhanji
    William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
    Intensive Care Med 35:671-7. 2009
    ..To evaluate the relationship between global oxygen delivery (DO(2)I), microvascular flow and tissue oxygenation in patients who did and did not develop complications following major abdominal surgery...
  42. ncbi Oral pathology quiz #17: incidental red and white lesion
    Howard Gross
    Department of Periodontology and Dental Hygiene, University of Detroit Mercy School of Dentistry, USA
    J Mich Dent Assoc 88:34, 52-3. 2006
  43. ncbi [Anterolateral thigh perforator flaps for facial reconstruction after tumour surgery]
    Alexander Gaggl
    Abteilung für Mund, Kiefer und Gesichtschirurgie, Landeskrankenhaus Klagenfurt, St Veiterstrasse 47, A 9020, Klagenfurt, Osterreich
    Mund Kiefer Gesichtschir 10:315-23. 2006
    ..In the following study our experiences with microvascular anterolateral thigh perforator flaps (ALTPF) in reconstruction of the face following ablative tumour surgery are described and discussed in comparison to the present literature...
  44. ncbi Oral cancer in Enugu, Nigeria, 1998-2003
    Chima Oji
    Department of Oral and Maxillofacial Surgery, University of Nigeria Teaching Hospital, Enugu, Nigeria
    Br J Oral Maxillofac Surg 45:298-301. 2007
    ..We need an urgent awareness campaign, and programmes for the prevention and early detection of oral cancer, in Nigeria...
  45. ncbi Oral squamous cell carcinoma incidence by subsite among diverse racial and ethnic populations in California
    Lihua Liu
    Los Angeles Cancer Surveillance Program, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:470-80. 2008
    ..The aim of this report was to examine the oral cancer incidence by sex, race/ethnicity, and anatomical subsite...
  46. ncbi Relevance of skip metastases for squamous cell carcinoma of the oral tongue and the floor of the mouth
    Fernando L Dias
    Department of Head and Neck Surgery, Brazilian National Cancer Institute, Av Alexandre Ferreira 190, Rio de Janeiro, RJ 22470 220, Brazil
    Otolaryngol Head Neck Surg 134:460-5. 2006
    ..To analyze the therapeutic implications of the distribution of neck metastases (NM) in patients with squamous cell carcinoma (SCC) of the tongue and the floor of the mouth (FOM)...
  47. ncbi Chondroradionecrosis of larynx following radiotherapy for metastatic neck disease originating from oral carcinoma
    F Bekiroglu
    Maxillofacial Department, New Cross Hospital, Wolverhampton, United Kingdom
    Int J Oral Maxillofac Surg 36:459-61. 2007
    ..This resulted in preservation of laryngeal function, and avoided further exploration of the irradiated neck and possible further skin loss...
  48. ncbi Cancer of the oral cavity- a growing concern in the Micronesia: a case report from the Marshall Islands
    Sangita Bhandary
    Head and Neck Surgery, Majuro Hospital, Marshall Islands
    Pac Health Dialog 10:76-8. 2003
    ..The epidemiology, etiology and recent approaches in the management of oral cavity cancer has been discussed along with a case report of advanced cancer of the floor of the mouth from the Marshall Islands...
  49. ncbi [About surgical treatment of mucous membrane of mouth floor and tongue cancer]
    P V Svetitskiĭ
    Stomatologiia (Mosk) 84:55-7. 2005
    In the department of head and neck tumors of Rostov Research Oncological Institute the operation on advanced mouth floor and tongue cancer is proposed comprising removement of the regional lymph nodes and resection of the tongue and ..
  50. ncbi Effectiveness of routine follow-up of patients treated for T1-2N0 oral squamous cell carcinomas of the floor of mouth and tongue
    Matthias Adrianus Wilhelmus Merkx
    Department of Oral and Maxillofacial Surgery, University Medical Center St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Head Neck 28:1-7. 2006
    ..The purpose of this study was to determine the benefit of our 10-year follow-up program in patients with stage I and II squamous cell carcinoma (SCC) of the floor of mouth and tongue...
  51. ncbi p53 mutations and human papillomavirus infection in oral squamous cell carcinomas: correlation with overall survival
    Ruzica Kozomara
    Clinic of Maxillofacial Surgery, Military Medical Academy, Belgrade, Sebia and Montenegro
    J Craniomaxillofac Surg 33:342-8. 2005
    ..The study investigated the pattern of p53 gene mutations and human papillomavirus (HPV) infection concerning their relation to overall survival in patients with oral squamous cell carcinomas of the tongue and floor of the mouth...
  52. ncbi Composite reconstruction in advanced cancer of the mouth floor: autogenous frozen-thawed mandibular bone and free flaps
    Luca Calabrese
    Division of Head and Neck Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Microsurgery 27:21-6. 2007
    ..The free forearm flap is effective in sealing the oral cavity, though further clinical and experimental studies are necessary to reduce late local complications...
  53. ncbi [The central island tongue flap for the reconstruction of the anterior floor of the mouth]
    J D Raguse
    Charite Universitatsmedizin Berlin, CVK, Klinik fur Mund, Kiefer und Gesichtschirurgie, Klinische Navigation und Robotik, Plastische Operationen, Augustenburgerplatz 1, 13353 Berlin, Germany
    Mund Kiefer Gesichtschir 11:53-7. 2007
    ..There are several techniques described for the reconstruction of the anterior floor of mouth after tumour surgery. Here, we point out the advantages of the central island tongue flap for this indication...
  54. ncbi [Cancer of the floor of the mouth in a ninety-four year old female patient: a record and its justification]
    H Reychler
    Service de stomatologie et chirurgie maxillofaciale, clinique de cancérologie cervicomaxillofaciale, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, 1200 Bruxelles, Belgique
    Rev Stomatol Chir Maxillofac 108:143-5. 2007
    ..Patient's age is known to have no influence on either treatment or prognosis of oral squamous cell carcinoma...
  55. ncbi Prosthetic rehabilitation of orofacial donor site fistula following surgical reconstruction: a clinical report
    T Pavan Kumar
    Department of Prosthodontics, Ragas Dental College and Hospital, Chennai, India
    J Prosthodont 17:336-9. 2008
    ..This clinical report describes a simple, economical, and effective technique for the prosthetic rehabilitation of a patient with oro-cutaneous fistula due to donor site dehiscence following tumor defect reconstruction...
  56. ncbi Does tumor depth affect nodal upstaging in squamous cell carcinoma of the head and neck?
    Lee W T Alkureishi
    Plastic Surgery Unit, Canniesburn Hospital, Glasgow, United Kingdom
    Laryngoscope 118:629-34. 2008
    ....
  57. ncbi [In vivo diagnosis of epithelial changes of the oropharynx using confocal microscopy]
    T Just
    Klinik und Poliklinik für Hals Nasen Ohrenheilkunde, Kopf und Halschirurgie Otto Körner der Universität Rostock, Rostock
    Laryngorhinootologie 87:174-80. 2008
    ..The specific aim of this investigation was to evaluate whether this in vivo tool supplies essential information for the surgeon prior to operation or not...
  58. ncbi [Outcome of surgical and adjuvant radiotherapy treatment of T3-T4 squamous cell carcinoma of the floor of the mouth: evaluation of oncological control and treatment related morbidity]
    A Hitter
    CHU A Michallon, Clinique ORL, Pôle tête et cou et Chirurgie réparatrice, 38043 Grenoble 09, France
    Rev Laryngol Otol Rhinol (Bord) 128:155-62. 2007
    ..The aims of this study were to evaluate the therapeutic outcome and morbidity associated with management of squamous cell carcinoma (SCC) T3-T4 of the floor of the mouth...
  59. ncbi Free flaps in oral cavity reconstruction: when you need them and when you don't
    Gregory K Hartig
    Otolaryngology Head and Neck Surgery, University of Wisconsin, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 69:S19-21. 2007
  60. ncbi Additional use of DNA-image cytometry improves the assessment of resection margins
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University, Dusseldorf, Germany
    J Oral Pathol Med 36:472-5. 2007
    ..The purpose of this study was to determine the prognostic value of DNA-image cytometry in the assessment of resection margins...
  61. ncbi Oral rehabilitation of a mandibular discontinuity defect: a clinical report
    Peter J Gerngross
    Michael E DeBakey V A Medical Center, Houston, USA
    Tex Dent J 125:438-41. 2008
    ..It is important to inform them that prosthetic reconstruction may restore structures and continuity, but it may not restore function...
  62. ncbi Diagnostic delay of oral squamous cell carcinoma in two diagnosis centers in Córdoba Argentina
    R A Morelatto
    Department of Oral Pathology, Clinical Stomatology I and II B, Faculty of Dentistry, National University of Cordoba, Cordoba, Argentina
    J Oral Pathol Med 36:405-8. 2007
    ..The aim of the present study was to investigate diagnostic delay in oral cancer (OC) in two diagnosis centers in Córdoba, Argentina. Special attention was paid to the role of the patient and the professional in the diagnostic delay...
  63. doi Buccinator myomucosal island flap for reconstruction of the floor of the mouth
    Silvano Ferrari
    Department of Maxillo Facial Surgery, University and Hospital of Parma, Parma, Italy
    J Oral Maxillofac Surg 66:394-400. 2008
  64. ncbi Tumor-specific genetic expression profile of metastatic oral squamous cell carcinoma
    Eduardo Mendez
    Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, Washington 98195, USA
    Head Neck 29:803-14. 2007
    ..Metastasis is the most important predictor of survival in patients with oral squamous cell carcinoma (OSCC). We tested the hypothesis that there is a genetic expression profile associated with OSCC metastasis...
  65. ncbi Oral squamous cell carcinoma: a clinicopathologic review of 233 cases in Lagos, Nigeria
    Olajumoke Ajibola Effiom
    Department of Oral Pathology and Biology, College of Medicine, University of Lagos, Lagos, Nigeria
    J Oral Maxillofac Surg 66:1595-9. 2008
    ....
  66. ncbi Oral medicine case book 6. Two cases of oral squamous cell carcinomas (OSC)
    J de Waal
    Division of Oral Medicine and Periodontology, University of Western Cape
    SADJ 63:170-1. 2008
  67. ncbi Epidemiological and histopathological data and E-cadherin-like prognostic factors in early carcinomas of the tongue and floor of mouth
    Marcelo B Menezes
    Head and Neck Section of Surgery Department, Santa Casa de Sao Paulo, School of Medicine, Rua Cesario Mota Jr, 112, CEP 01221 020 Vila Buarque, Sao Paulo, SP, Brazil
    Oral Oncol 43:656-61. 2007
    ..advances in diagnosis and treatment, overall survival of people with squamous cell carcinomas of the tongue and mouth floor continues to be low. Prognostic information is essential for improved evaluation and treatment...
  68. ncbi Medial sural artery perforator flap for intraoral reconstruction following cancer ablation
    Shao Liang Chen
    Division of Plastic Surgery, Department of Surgery, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC
    Ann Plast Surg 61:274-9. 2008
    ..Other advantages of minimizing donor site morbidity include maintaining the function of the medial gastrocnemius muscle, avoiding the need to sacrifice major arteries of the leg, and possible primary closure of the donor defect...
  69. ncbi Expression of E-cadherin in cervical lymph nodes from primary oral squamous cell carcinoma patients
    Lai ping Zhong
    Department of Oral and Maxillofacial Surgery, Ninth People s Hospital, School of Medicine, Shanghai Jiao Tong University, No 639 Zhizaoju Road, Shanghai 200011, China
    Arch Oral Biol 52:740-7. 2007
    ..E-cadherin plays a key role in cell-to-cell adhesion. E-cadherin expression in the metastatic cervical lymph node, especially in the micrometastatic cervical lymph node has seldom been reported in OSCC patients...
  70. ncbi Epithelioid hemangioendothelioma of the oral cavity
    Z J Sun
    Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 237 Luo Yu Road, Wuhan 430079, Hubei, China
    Oral Dis 13:244-50. 2007
    ..To investigate the clinicopathological characteristics and biologic behaviour of epithelioid hemangioendothelioma in the oral cavity...
  71. ncbi Two designs of platysma myocutaneous flap for reconstruction of oral and facial defects following cancer surgery
    L W Peng
    Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, PR China
    Int J Oral Maxillofac Surg 34:507-13. 2005
    ..It is recommended that the vertical design be used for reconstruction of buccal mucosa defects, and the transverse design for mouth-floor and facial defects...
  72. ncbi The clinical relevance of epithelial dysplasia in the surgical margins of tongue and floor of mouth squamous cell carcinoma: an analysis of 37 patients
    M Weijers
    Department of Oral and Maxillofacial Surgery Pathology, University Hospital Vrije Universiteit ACTA, Amsterdam, The Netherlands
    J Oral Pathol Med 31:11-5. 2002
    ..The clinical relevance of the presence of epithelial dysplasia in the margins of surgically removed oral squamous cell carcinoma is still unclear...
  73. ncbi Tobacco smoking history and presentation of oral squamous cell carcinoma
    Brian L Schmidt
    Legacy Hospital System, Portland, OR, USA
    J Oral Maxillofac Surg 62:1055-8. 2004
    ..The purpose of this study was to examine the relationship between smoking versus never-smoking history and the stage and site of presentation of oral squamous cell carcinoma...
  74. ncbi [Palliative surgery in squamous cell carcinoma of the anterior floor of the mouth]
    G Bachmann
    Øre nese hals avdelingen, Universitetssykehuset i Nord Norge, Tromsø, Norwegen
    HNO 52:627-30. 2004
    ..Using a combination of palliative procedures, it is possible not only to achieve a full local remission but also to provide a high quality of life...
  75. ncbi Predictive factors of occult metastasis and prognosis of clinical stages I and II squamous cell carcinoma of the tongue and floor of the mouth
    Tânia Mara Pimenta Amaral
    Department of Semiology and Pathology, School of Dentistry, Federal University of Minas Gerais, Rua Juiz de Fora, 1090 102, 30180 061 Belo Horizonte, Brazil
    Oral Oncol 40:780-6. 2004
    ....
  76. ncbi Axillary nodal metastasis from oral and maxillofacial cancers: a report of 3 cases
    Aung Lwin Oo
    Maxillofacial Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Oral Maxillofac Surg 62:1019-24. 2004
  77. ncbi Smokeless tobacco (shamma) and oral cancer in Saudi Arabia
    W F Allard
    Department of Dentistry, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia
    Community Dent Oral Epidemiol 27:398-405. 1999
    ..These data suggest that there is a relationship between the factors smokeless tobacco product (shamma), frequency of oral cancer, and Jizan province: oral cancer appears to be more common in this province where shamma is also common...
  78. ncbi The status of the deep surgical margins in tongue and floor of mouth squamous cell carcinoma and risk of local recurrence; an analysis of 68 patients
    M Weijers
    Department of Oral and Maxillofacial Surgery Pathology, Vu University Medical Center ACTA, Amsterdam, The Netherlands
    Int J Oral Maxillofac Surg 33:146-9. 2004
    ..5 cm, but not into the deep surgical margin, does not necessarily seem to require additional treatment. The pattern of invasion and the presence or absence of perineural spread were not significantly related with local recurrence either...
  79. ncbi [Contribution of the semi-free radial forearm flap for head and neck reconstruction]
    H Benateau
    Service de Stomatologie et Chirurgie Maxillo Faciale, CHU Cote de Nacre, 14033 Caen Cedex
    Rev Stomatol Chir Maxillofac 103:74-8. 2002
    ..This version of the radial forearm flap can be a method of choice for some complex microvascular reconstruction in the head and neck region...
  80. ncbi Lipomas of the oral cavity: clinical findings, histological classification and proliferative activity of 46 cases
    E R Fregnani
    Oral Pathology and Semiology, University of Campinas Dental School, Av Limeira, 901, Caixa Postal 52, CEP 13414 900, Piracicaba SP, Brazil
    Int J Oral Maxillofac Surg 32:49-53. 2003
    ..All lesions were removed surgically and none showed recurrence, regardless of the various proliferative activities...
  81. ncbi [Functional results succeeding primary combined external radiotherapy and brachytherapy for head and neck tumors]
    M Scheithauer
    Universitätsklinik und Poliklinik für Hals Nasen Ohrenheilkunde der Universität Ulm, Germany
    Laryngorhinootologie 81:712-7. 2002
    ..The functional results and the complication rate in stage III and IV tumors of the oral tongue, floor of mouth and oropharynx are described in a patients series...
  82. ncbi Assessment of perfusion of facial microvascular transplants and early detection of ischemia by perfusion-CT scan
    Alexander Gaggl
    Department of Oral and Maxillofacial Surgery, University Hospital Graz, Austria
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:425-31. 2002
    ..In this study, the use of perfusion-CT scans to predict ischemia in microvascular transplants of the face was examined...
  83. ncbi Lining the mouth floor with prelaminated fascio-mucosal free flaps: clinical experience
    L Chiarini
    Section of Dentistry, Department of Neurosciences, Head and Neck and Rehabilitation, Faculty of Medicine, University of Modena and Reggio Emilia, Italy
    Microsurgery 22:177-86. 2002
    Soft-tissue defects of the mouth floor need thin, foldable, and pliable tissues able to preserve local anatomy as well as chewing, phonation, and deglutition...
  84. ncbi [Reconstruction of the anterior floor of the mouth with nasolabial flaps. Report of 10 years' experience]
    Peter Maurer
    Klinik und Poliklinik fur Mund, Kiefer und Plastische Gesichtschirurgie der Martin Luther Universität Halle Wittenberg, D 06097 Halle
    Schweiz Monatsschr Zahnmed 112:463-6. 2002
    ..to represent a functionally and aesthetically satisfactory alternative to reconstruction by microsurgery, in cases of small to medium-sized defects, especially in older, medically compromised patients with an enhanced surgical risk..
  85. ncbi Primary ectopic thyroid papillary carcinoma in the floor of the mouth and tongue: a case report
    S Y Kao
    Department of Dentistry, Oral and Maxillofacial Surgery, Veterans General Hospital Taipei and School of Dentistry, National Yang Ming University Taipei, Taiwan, ROC
    Br J Oral Maxillofac Surg 40:213-5. 2002
    ..Pathological examination of the thyroid gland showed no primary cancer. We review publications about ectopic thyroid and the value of antithyroglobulin immunostaining for diagnosis and treatment of the tumour...
  86. ncbi Cathepsin expression in oral squamous cell carcinoma: relationship with clinicopathologic factors
    Goro Kawasaki
    The First Department of Oral and Maxillofacial Surgery, Nagasaki University, Japan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93:446-54. 2002
    ....
  87. ncbi Clinicopathological factors in early squamous cell carcinoma of the tongue and floor of the mouth, in Biscay (the Basque Country, Spain)
    R Martinez-Conde
    Departamento de Estomatología Universidad del País Vasco E H U Leioa 48940 Vizcaya
    Med Oral 6:87-94. 2001
    ..A study is made of the main clinicopathological factors in squamous cell carcinoma (SCC) of the tongue and floor of the mouth in the province of Vizcaya (Biscay) (The Basque Country, Spain), and their relation to patient prognosis...
  88. ncbi Expression of telomerase RNA in oesophageal and oral cancer
    M G Downey
    University Departments of Medical Oncology, Pathology and Surgery, University of Glasgow, UK
    J Oral Pathol Med 30:577-81. 2001
    ..Generally concordant hTR status between biopsy and resection suggest that biopsy may have a role in selecting candidates for telomerase inhibition therapy...
  89. ncbi Metastatic cancer to the floor of mouth: the lingual lymph nodes
    Jay M Dutton
    Department of Otolaryngology and Bronchoesophagology, Rush Medical College, 1725 W Harrison, Suite 340, Chicago, Illinois 60612, USA
    Head Neck 24:401-5. 2002
    ..Traditional discontinuous neck dissections do not provide for removal of floor of mouth tissue along with the primary and neck specimens...
  90. ncbi Influence of marginal and segmental mandibular resection on the survival rate in patients with squamous cell carcinoma of the inferior parts of the oral cavity
    Diana Wolff
    Department of Oral and Cranio Maxillofacial Surgery, University of Heidelberg Medical School, Germany
    J Craniomaxillofac Surg 32:318-23. 2004
    ..The aim of this retrospective study was to investigate whether radical (segmental resection) or conservative (marginal) resection of mandibular bone influenced patients, survival...
  91. ncbi [Occult metastases of oral cavity cancers]
    M Dimitrijevic
    Institut za otorinolaringologiju i maksilofacijalnu hirurgiju, Klinicki centar Srbije, Beograd
    Acta Chir Iugosl 51:77-81. 2004
    ..2% of the time. Malignant tumors of the oral cavity are always the indication for neck dissection, even in N0 category, on account of high proportion of occult metastases...
  92. ncbi [On the indications for and morbidity of segmental resection of the mandible for squamous cell carcinoma in the lower oral cavity]
    A Abler
    Klinik fur Kiefer und Gesichtschirurgie, Plastische Operationen, Klinikum Stuttgart Katharinenhospital
    Mund Kiefer Gesichtschir 9:137-42. 2005
    ..Consequently, based on the rules of safety margins to all planes that are recommended for soft tissues, each lesion that is closer than 10 mm to the mandible needs resection of the bone...
  93. ncbi [Evaluation of local and regional spread of malignant tumors of the tongue and floor of the mouth]
    Milovan Dimitrijevic
    Klinicki centar Srbije, Institut za otorinolaringologiju i maksilofacijalnu hirurgiju, Beograd, Srbija i Crna Gora
    Vojnosanit Pregl 61:507-12. 2004
    ..Clinically observed regional spread (cN) and intraoperatively and histopathologically confirmed regional spread (pN) was lower, amounting to 56.8% in comparison to the corresponding T categories...
  94. ncbi Oral cancer at a Tasmanian tertiary referral clinic, the Royal Hobart Hospital 1996-2002
    L C Hogan
    Oral and Maxillofacial Surgery Registrar 2003, The Royal Hobart Hospital, Tasmania
    Aust Dent J 50:31-6. 2005
    ....
  95. ncbi Effect of induction chemotherapy on changes of laminin and syndecan expression in oral squamous cell carcinomas: a prospective, randomized, clinicopathologic and immunohistochemical study
    Zsolt Németh
    Department of Oral, Dental and Maxillofacial Surgery, Dental Faculty, Semmelweis University Budapest, H 1085 Budapest, Mária u 52, Hungary
    J Craniofac Surg 16:205-12. 2005
    ..The increase or stagnation of these clearly forecast a good prognosis, whereas their decrease was a definite indication of poor prognosis...
  96. ncbi Clinico-pathological features of squamous cell carcinoma of the oral cavity in patients <40 years of age
    T Sasaki
    Department of Oral and Maxillofacial Surgery, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
    J Oral Pathol Med 34:129-33. 2005
    ..The purpose of this study was to evaluate the clinico-pathological features of oral SCC among young people...
  97. ncbi Natural orifice surgery on thyroid gland: totally transoral video-assisted thyroidectomy (TOVAT): report of first experimental results of a new surgical method
    T Benhidjeb
    Department of General, Visceral, Vascular and Thoracic Surgery, Charite Universitatsmedizin Berlin, Berlin, Germany
    Surg Endosc 23:1119-20. 2009
    ..The main goal of our project was the investigation and introduction of a technique of totally endoscopic thyroid resection that is minimally invasive and safe for the patient and at the same time cosmetically optimal (scarless)...
  98. ncbi Sensitivity of direct immunofluorescence in oral diseases. Study of 125 cases
    Susana Mariela Sano
    Facultad de Odontología Universidad de Buenos Aires, Buenos Aires, Argentina
    Med Oral Patol Oral Cir Bucal 13:E287-91. 2008
    ....
  99. ncbi [Modified sternocleidomastoid myocutaneous flap for reconstruction of soft tissue defects following tumorectomy of maxillofacial region]
    Yi Lin
    Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou Zhejiang, 310006, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 24:452-4. 2010
    ..To investigate clinical effect and prognosis of the modified sternocleidomastoid (MSCM) myocutaneous flap for reconstruction of tissue defects in patients with oral carcinomas undergoing tumorectomy...
  100. ncbi [Cervicofacial cellulitis of dental origin and tracheal intubation]
    H Reyford
    , , CHRU Lille
    Ann Fr Anesth Reanim 14:256-60. 1995
    ..clinical and radiological control of localisation and extension of the cellulitis (mandibular, maxillar or mouth floor). In case of a foreseen difficult intubation, a fibrescope was used in the awake patient...
  101. ncbi Short-term chloral hydrate administration and cancer in humans
    Tmirah Haselkorn
    Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA
    Drug Saf 29:67-77. 2006
    ..Chloral hydrate, used as a hypnosedative in adults and children, has been shown to be genotoxic and carcinogenic in animal studies. We investigated the potential causal association between chloral hydrate exposure and cancer risk in humans...

Research Grants6

  1. ORAL MUCOSA MICROBIOTA IN HEALTH, CANCER & MUCOSITIS
    Donna Mager; Fiscal Year: 2004
    ..Detection on unusual microbial shifts in mucositis might suggest possible routes to minimizing this condition. ..
  2. Optical Imaging of Retinal Blood Circulation
    LEONARD WINCHESTER; Fiscal Year: 2005
    ..A noninvasive, realtime retinal imager allows the physicians to record and keep track of patients' retinal hemodynamics to detect early signs of ocular disorders. ..
  3. Raman Determination of Ligament Tension
    LEONARD WINCHESTER; Fiscal Year: 2006
    ..Measurements of MCL and ACL ligaments as functions of applied stress will be used to demonstrate the feasibility of the proposed technique. [unreadable] [unreadable] [unreadable] [unreadable]..
  4. Realtime Monitoring of Sublingual Blood Velocity
    LEONARD WINCHESTER; Fiscal Year: 2006
    ..This research is to investigate the utility of a new imaging technique for real-time measurements of blood velocity of the patient's tongue in the intensive care units. [unreadable] [unreadable] [unreadable]..
  5. Noninvasive Methemoglobin Monitoring Technology
    LEONARD WINCHESTER; Fiscal Year: 2007
    ..A noninvasive and reliable methemoglobin sensor will have great impact on therapeutic decision time. [unreadable] [unreadable] [unreadable]..
  6. OPTICAL DETECTION OF INTRAVENOUS INFILTRATION
    LEONARD WINCHESTER; Fiscal Year: 2008
    ..Specific aims of the Competing Continuation effort are: to refine the IV infiltration detection device, to conduct a clinical trial, and to submit a 510 (k) application to the U.S. Food and Drug Administration. ..