tympanic membrane

Summary

Summary: An oval semitransparent membrane separating the external EAR CANAL from the tympanic cavity (EAR, MIDDLE). It contains three layers: the skin of the external ear canal; the core of radially and circularly arranged collagen fibers; and the MUCOSA of the middle ear.

Top Publications

  1. pmc Fever detection in under 5 children in a tertiary health facility using the infrared tympanic thermometer in the oral mode
    Benedict O Edelu
    Department of Pediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, Nigeria
    Ital J Pediatr 37:8. 2011
  2. ncbi Negative emotional valence is associated with non-right-handedness and increased imbalance of hemispheric activation as measured by tympanic membrane temperature
    Ruth E Propper
    Department of Psychology, Merrimack College, North Andover, MA 01845, USA
    J Nerv Ment Dis 198:691-4. 2010
  3. ncbi Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: a randomized trial
    Steven D Rauch
    Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    JAMA 305:2071-9. 2011
  4. ncbi Ototoxic effect of topical ciclopirox as an antimycotic preparation
    Serdar Baylancicek
    Sisli Etfal Teaching and Research Hospital, Department of Otorhinolaryngology, Marmara University School of Medicine, Istanbul, Turkey
    Otol Neurotol 29:910-3. 2008
  5. pmc Imaging high-frequency periodic motion in the mouse ear with coherently interleaved optical coherence tomography
    Brian E Applegate
    Department of Biomedical Engineering, Texas A and M University, 337 Zachry Engineering Center, College Station, Texas 77843, USA
    Opt Lett 36:4716-8. 2011
  6. ncbi Assembling a functional tympanic membrane: signals from the external acoustic meatus coordinate development of the malleal manubrium
    M Mallo
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Stubeweg 51, D 79108 Freiburg, Germany
    Development 127:4127-36. 2000
  7. ncbi Clinical comparison of tympanic membrane displacement with invasive intracranial pressure measurements
    S Shimbles
    Regional Medical Physics Department and Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK
    Physiol Meas 26:1085-92. 2005
  8. ncbi Measurement accuracy of fever by tympanic and axillary thermometry
    Ilker Devrim
    Pediatric Infectious Disease Unit, Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
    Pediatr Emerg Care 23:16-9. 2007
  9. ncbi Tympanic temperature comparison with oral mercury thermometer readings in an OPD setting
    Mohammad Zafar Rabbani
    Department of ENT, Shifa College of Medicine, Islamabad
    J Coll Physicians Surg Pak 20:33-6. 2010
  10. ncbi Capillary hemangioma of the tympanic membrane
    Harukazu Hiraumi
    Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto City, Japan
    Am J Otolaryngol 26:351-2. 2005

Research Grants

  1. Ultrasound Characterization of Otitis Media
    Arne Voie; Fiscal Year: 2004
  2. Human middle-ear imaging, physiology, and biomechanics
    CHARLES RICHARD STEELE; Fiscal Year: 2013
  3. Middle-ear Mechanics in Normal and Pathological Ears
    John J Rosowski; Fiscal Year: 2013
  4. Avian Middle Ear Development
    SUSAN CAROLINE CHAPMAN; Fiscal Year: 2012
  5. Ossicle vibration measurements in conductive hearing loss
    Steven L Jacques; Fiscal Year: 2013
  6. Biomechanical Measurement and Modeling of Normal and Diseased Middle Ears
    Rong Z Gan; Fiscal Year: 2013
  7. Molded Hydrogel Tympanic Membrane Repair Constructs
    WILSON CANNOY PRITCHARD; Fiscal Year: 2011
  8. Dx Ear: An automated tool for diagnosis of otitis media
    JELENA KOVACEVIC; Fiscal Year: 2010
  9. Computer-based holography and middle-ear function
    John J Rosowski; Fiscal Year: 2013
  10. Backward and Forward Driven Eardrum Motions
    Jeffrey Tao Cheng; Fiscal Year: 2013

Detail Information

Publications289 found, 100 shown here

  1. pmc Fever detection in under 5 children in a tertiary health facility using the infrared tympanic thermometer in the oral mode
    Benedict O Edelu
    Department of Pediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, Nigeria
    Ital J Pediatr 37:8. 2011
    ..The oral mercury-in-glass thermometer which has relatively good accuracy cannot be used in children less than 5 years because it requires their cooperation...
  2. ncbi Negative emotional valence is associated with non-right-handedness and increased imbalance of hemispheric activation as measured by tympanic membrane temperature
    Ruth E Propper
    Department of Psychology, Merrimack College, North Andover, MA 01845, USA
    J Nerv Ment Dis 198:691-4. 2010
    ..1983;47:305-306) as a measure of emotional valence and tympanic membrane temperature (TMT) as a measure of hemispheric activity...
  3. ncbi Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: a randomized trial
    Steven D Rauch
    Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    JAMA 305:2071-9. 2011
    ..Recently, many patients' symptoms have been managed with intratympanic steroid therapy. No satisfactory comparative effectiveness study to support this practice exists...
  4. ncbi Ototoxic effect of topical ciclopirox as an antimycotic preparation
    Serdar Baylancicek
    Sisli Etfal Teaching and Research Hospital, Department of Otorhinolaryngology, Marmara University School of Medicine, Istanbul, Turkey
    Otol Neurotol 29:910-3. 2008
    ..To evaluate the ototoxicity of ciclopirox-containing solution as an otologic preparation for the treatment of otomycosis...
  5. pmc Imaging high-frequency periodic motion in the mouse ear with coherently interleaved optical coherence tomography
    Brian E Applegate
    Department of Biomedical Engineering, Texas A and M University, 337 Zachry Engineering Center, College Station, Texas 77843, USA
    Opt Lett 36:4716-8. 2011
    ..The algorithm was evaluated by measuring the vibratory response of mouse tympanic membrane to a pure tone stimulus.
  6. ncbi Assembling a functional tympanic membrane: signals from the external acoustic meatus coordinate development of the malleal manubrium
    M Mallo
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Stubeweg 51, D 79108 Freiburg, Germany
    Development 127:4127-36. 2000
    In terrestrial mammals, hearing starts with the perception of acoustic pressure by the tympanic membrane. Vibrations in this membrane are then transduced into the inner ear by the ossicle chain of the middle ear, composed of the malleus, ..
  7. ncbi Clinical comparison of tympanic membrane displacement with invasive intracranial pressure measurements
    S Shimbles
    Regional Medical Physics Department and Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK
    Physiol Meas 26:1085-92. 2005
    ..This study evaluated a technique using tympanic membrane displacement (TMD) measurements, which has been reported to provide a reliable, non-invasive measure of ICP...
  8. ncbi Measurement accuracy of fever by tympanic and axillary thermometry
    Ilker Devrim
    Pediatric Infectious Disease Unit, Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
    Pediatr Emerg Care 23:16-9. 2007
    ..In this study, we aimed to compare tympanic infrared thermometers with the conventional temperature option, mercury-in-glass thermometer, which is historical standard in the clinical conditions...
  9. ncbi Tympanic temperature comparison with oral mercury thermometer readings in an OPD setting
    Mohammad Zafar Rabbani
    Department of ENT, Shifa College of Medicine, Islamabad
    J Coll Physicians Surg Pak 20:33-6. 2010
    ..To observe and compare the Tympanic Temperature (TT) readings with the Oral Mercury Thermometer (OMT) in an OPD setting...
  10. ncbi Capillary hemangioma of the tympanic membrane
    Harukazu Hiraumi
    Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto City, Japan
    Am J Otolaryngol 26:351-2. 2005
    We report a case of capillary hemangioma of the tympanic membrane in a 51-year-old man with conductive hearing loss, otalgia, and otorrhea...
  11. ncbi Lack of plasminogen does not alter the early inflammatory response following a tympanic membrane perforation: a study in plasminogen-deficient mice
    Annika Hansson Prestwich
    Department of Clinical Sciences, Otorhinolaryngology, Umea University, Umea, Sweden
    Acta Otolaryngol 128:1294-302. 2008
    ..These findings give further insight into the mechanisms resulting in a clinically seen chronic tympanic membrane (TM) perforation and thus possible therapeutic strategies to replace today's conventional surgical treatment ..
  12. ncbi An experimental study of tympanic membrane and manubrium vibrations in rats
    F Akache
    McGill Auditory Sciences Laboratory, McGill University, Montreal, Canada
    Audiol Neurootol 12:49-58. 2007
    ..characterize the mechanics of the rat middle ear by measuring frequency responses at multiple points on the tympanic membrane and manubrium. A laser Doppler vibrometer was used to measure the vibrations...
  13. ncbi The relationship between intracranial pressure and tympanic membrane displacement
    A Reid
    Institute of Sound and Vibration Research, University of Southampton, UK
    Br J Audiol 24:123-9. 1990
    ..Indirect measurement of perilymphatic pressure may be investigated by observing tympanic membrane (TM) displacement during stapedial reflex contraction...
  14. ncbi Cavernous hemangioma of the tympanic membrane and external ear canal
    Giuseppe Magliulo
    Department of Otorhinolaryngology, Audiology and Phoniatrics G Ferreri, University La Sapienza, Rome, Italy
    Am J Otolaryngol 28:180-3. 2007
    The aims of this study are to document the occurrence of a cavernous hemangioma of the tympanic membrane (TM) and external auditory canal (EAC) that invaded the middle ear spaces and to review the relevant literature.
  15. pmc Clinical utility of laser-Doppler vibrometer measurements in live normal and pathologic human ears
    John J Rosowski
    Eaton Peabody Lab, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ear Hear 29:3-19. 2008
    ..vibrometer (LDV) is a research tool that can be used to quickly measure the sound-induced velocity of the tympanic membrane near the umbo (the inferior tip of the malleus) in live human subjects and patients...
  16. ncbi Endoscopic intratympanic methylprednisolone injection for treatment of refractory sudden sensorineural hearing loss and one case in pregnancy
    Yang Chen
    Department of Otolaryngology Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi an, China
    J Otolaryngol Head Neck Surg 39:640-5. 2010
    ..to evaluate the effectiveness of transtympanic methylprednisolone injection in patients with refractory sudden sensorineural hearing loss via endoscopic diode laser myringotomy...
  17. pmc Cisplatin-induced ototoxicity: effect of intratympanic dexamethasone injections
    Gerhard W Hill
    Division of Otolaryngology, Departments of Surgery, University of Connecticut Health Center, Farmington, Connecticut, USA
    Otol Neurotol 29:1005-11. 2008
    ..Intratympanic (IT) application of dexamethasone will reduce ototoxicity associated with systemic cisplatin therapy...
  18. ncbi Can intratympanic dexamethasone protect against cisplatin ototoxicity in mice with age-related hearing loss?
    Kourosh Parham
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Otolaryngol Head Neck Surg 145:635-40. 2011
    ..To determine whether intratympanic (i.t.) dexamethasone ameliorates cisplatin-induced ototoxicity in a mouse model of presbycusis...
  19. ncbi Acoustic responses of the human middle ear
    S E Voss
    Eaton Peabody Laboratory of Auditory Physiology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Hear Res 150:43-69. 2000
    ..Four response variables were measured with acoustic stimulation at the tympanic membrane: stapes velocity, middle-ear cavity sound pressure, acoustic impedance at the tympanic membrane and acoustic ..
  20. ncbi Laser Doppler vibrometry of the middle ear in humans: derivation dependence, variability, and bilateral differences
    Irina Arechvo
    Department of Ear, Nose, and Throat Diseases, Vilnius University Emergency Hospital, Vilnius, Lithuania
    Medicina (Kaunas) 45:878-86. 2009
    ..Derivation dependence, inter- and intrasubject/intertest variability, bilateral differences of the eardrum vibration characteristics have been investigated using laser Doppler vibrometry (LDV)...
  21. ncbi Ototoxic effect of topical oxiconazole and terbinafine in rats
    Emine Aydin
    Department of Otorhinolaryngology, Ankara Training and Research Hospital, Ankara, Turkey
    J Otolaryngol Head Neck Surg 41:78-83. 2012
    ..To assess the ototoxic effects of topically applied oxiconazole and terbinafine by means of auditory brainstem responses in rats...
  22. ncbi New aspects in the clinical diagnosis of otosclerosis using laser Doppler vibrometry
    Andre Jakob
    TU Dresden, Department of Medicine, Clinic of Otorhinolaryngology, Dresden, Germany
    Otol Neurotol 30:1049-57. 2009
    ..Laser Doppler vibrometry (LDV) applied to umbo motion measurement in healthy and otosclerotic ears shows statistically tested differences...
  23. ncbi Effect of nystatin on Guinea Pigs' inner ear
    Owen Woods
    Department of Otolaryngology Head and Neck Surgery, Sainte Justine University Hospital Center, Montreal University, 3175 Cote Sainte Catherine, Montreal, QC H3T1C5, Canada
    Neurotox Res 20:301-6. 2011
    ..Though it is safe for external ear use, no study has proven its safety in cases of tympanic membrane perforation (TMP)...
  24. ncbi Ventriculoperitoneal shunt as treatment for perilymphatic fistula: a report of six cases
    Dudley J Weider
    Department of Otolaryngology, Dartmouth Medical School, Hanover, New Hampshire, USA
    Int Tinnitus J 11:137-45. 2005
    ..All but one had benign intracranial hypertension. All six felt better (less disequilibrium, tinnitus, and pressure and occasional hearing improvement) after LP with removal of 15-20 ml of cerebrospinal fluid...
  25. ncbi Tympanic membrane vessel revisited: a study in an animal model
    Sten Hellstrom
    Department of Clinical Science, Otorhinolaryngology, University Hospital of Umea, Sweden
    Otol Neurotol 24:494-9. 2003
    The present study aimed at elucidating whether there are blood vessels in the semitransparent portion of the tympanic membrane.
  26. ncbi Temperament, tympanum, and temperature: four provisional studies of the biobehavioral correlates of tympanic membrane temperature asymmetries
    W Thomas Boyce
    Institute of Human Development and School of Public Health, University of California, Berkeley 94720 1190, USA
    Child Dev 73:718-33. 2002
    Previous research in both humans and nonhuman primates suggests that subtle asymmetries in tympanic membrane (TM) temperatures may be related to aspects of cognition and socioaffective behavior...
  27. pmc Imaging the human tympanic membrane using optical coherence tomography in vivo
    Hamid R Djalilian
    Department of Otolaryngology Head and Neck Surgery, University of California Irvine, Orange, CA 92868, USA
    Otol Neurotol 29:1091-4. 2008
    ..Using this technology, we have imaged in vivo the human tympanic membrane (TM) in the office clinic setting and characterized TM microstructure in normal and pathologic conditions.
  28. ncbi The effect of local administration of N-acetylcysteine in perforated rat tympanic membrane: an experimental study in myringosclerosis
    Cengiz Ozcan
    Department of Otorhinolaryngology, Mersin University, School of Medicine, Mersin, Turkey
    Pharmacol Res 45:5-9. 2002
    ..lipid peroxidation and nitric oxide (NO) (nitrite/nitrate) levels in experimental myringotomized rat tympanic membrane. Thirty adult rats were used and the upper posterior quadrant of the tympanic membranes of rats was ..
  29. ncbi Direct application of keratinocyte growth factor, basic fibroblast growth factor and transforming growth factor-alpha during healing of tympanic membrane perforation in glucocorticoid-treated rats
    Shin Ichi Ishimoto
    Department of Otolaryngology, University of Tokyo, Japan
    Acta Otolaryngol 122:468-73. 2002
    ..application of growth factors in the form of ear drops may counteract impairment of wound healing in the tympanic membrane (TM)...
  30. ncbi The inhibitory effect of topical N-acetylcysteine application on myringosclerosis in perforated rat tympanic membrane
    Cengiz Ozcan
    Department of Otorhinolaryngology, School of Medicine, Mersin University, Mersin, Turkey
    Int J Pediatr Otorhinolaryngol 63:179-84. 2002
    ..N-acetylcysteine is a well-known anti-oxidant and anti-inflammatory agent. In this study, we aimed to investigate the preventive effect of N-acetylcysteine on myringosclerosis in myringotomized rat tympanic membranes...
  31. ncbi Mechanical filtering for narrow-band hearing in the weta
    Kathryn Lomas
    University of Auckland, School of Biological Sciences, Auckland, New Zealand
    J Exp Biol 214:778-85. 2011
    ..We present a new model showing how the thickened region might confer a mechanical gain onto the activation of the crista acustica sensory neurons during the sound-induced oscillations...
  32. ncbi Tympanic membrane perforation repair with acellular porcine submucosa
    Jeffrey H Spiegel
    Department of Otolaryngology Head and Neck Surgery, Boston University School of Medicine, Boston, Massachusetts, USA
    Otol Neurotol 26:563-6. 2005
    To evaluate the efficacy of acellular porcine small intestine submucosa in the repair of chronic tympanic membrane perforations...
  33. ncbi Is tympanic membrane thermometry the best method for recording temperature in children?
    Paula L Dew
    Children s Hospital at Home CHAH Team, George Eliot Hospital NHS Trust, Nuneaton, UK
    J Child Health Care 10:96-110. 2006
    b>Tympanic membrane thermometry has become increasingly popular for measuring temperature in children...
  34. pmc Computer-assisted time-averaged holograms of the motion of the surface of the mammalian tympanic membrane with sound stimuli of 0.4-25 kHz
    John J Rosowski
    Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Hear Res 253:83-96. 2009
    Time-averaged holograms describing the sound-induced motion of the tympanic membrane (TM) in cadaveric preparations from three mammalian species and one live ear were measured using opto-electronic holography...
  35. ncbi A review on the use of hyaluronic acid in tympanic membrane wound healing
    Bing Mei Teh
    Ear Sciences Centre, School of Surgery, The University of Western Australia, M507, 35 Stirling Highway, Nedlands, Western Australia, 6009, Australia
    Expert Opin Biol Ther 12:23-36. 2012
    b>Tympanic membrane perforation represents a significant morbidity, especially if it occurs during a child's speech and language development...
  36. ncbi Increased anger is associated with increased hemispheric asymmetry: support for anger-tympanic membrane relationships
    Ruth E Propper
    Psychology Department, Montclair State University, 1 Normal Avenue, Montclair, NJ 07043, USA
    J Nerv Ment Dis 199:716-20. 2011
    ..is more active (as indicated by increased absolute difference in temperature between the right and left tympanic membrane (ar-lTMT; Propper et al., J Nerv Ment Dis 198:691-694, 2010)...
  37. ncbi Tympanosclerosis and our surgical results
    Hale Aslan
    Department of Otorhinolaryngology and Head and Neck Surgery, Ataturk Research and Training Hospital, Ministry of Health, Izmir, Turkey
    Eur Arch Otorhinolaryngol 267:673-7. 2010
    ..by the deposition of calcareous plaques following hyaline degeneration in the fibrous layer of the tympanic membrane and inside middle ear mucosa. It usually results from prior middle ear infections...
  38. pmc Non-ossicular signal transmission in human middle ears: Experimental assessment of the "acoustic route" with perforated tympanic membranes
    Susan E Voss
    Picker Engineering Program, Smith College, 51 College Lane, Northampton, Massachusetts 01063, USA
    J Acoust Soc Am 122:2135-53. 2007
    ..Some features of the frequency dependence of H(P(CAV) ) and H(WPD) can be interpreted in terms of a structure-based lumped-element acoustic model of the perforation and middle-ear cavities...
  39. ncbi Infrared tympanic thermometry in comparison with other temperature measurement techniques in febrile children
    Marianne M Nimah
    Division of Critical Care Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Pediatr Crit Care Med 7:48-55. 2006
    ..To determine whether infrared tympanic thermometry (ITT) measurements more accurately reflect core body temperatures than axillary, forehead, or rectal measurements during fever cycles in children...
  40. ncbi Ultrasonographic evaluation of the external ear canal and tympanic membrane in dogs
    Jeongmin Lee
    Department of Veterinary Diagnostic Imaging, College of Veterinary Medicine, Kyungpook National University, 1370, Sangyeok dong, Buk Ku, Daegu, Korea
    Vet Radiol Ultrasound 47:94-8. 2006
    Ultrasonographic imaging of the canine external ear canal, tympanic membrane, and tympanic bulla was described in five healthy beagle dogs before and after infusion of saline into the ear canal. Saline served as an acoustic window...
  41. ncbi Cortical representation of tympanic membrane movements due to pressure variation: an fMRI study
    Agnes Job
    Institut de Recherche Biomédicale des Armées, antenne CRSSA, 24 Avenue des Maquis du Gresivaudan, La Tronche, France
    Hum Brain Mapp 32:744-9. 2011
    ..We applied small air pressure variations to the tympanic membrane while performing a 3T-fMRI study...
  42. pmc Diagnostic utility of laser-Doppler vibrometry in conductive hearing loss with normal tympanic membrane
    John J Rosowski
    Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA
    Otol Neurotol 24:165-75. 2003
    ..More generally, we hypothesize that laser-Doppler vibrometry measurements of umbo velocity can give information about how differences in the impedance that the ossicles work against affect middle-ear function...
  43. ncbi Tympanic membrane temperature and emotional dispositions in preschool-aged children: a methodological study
    Megan R Gunnar
    Institute of Child Development, University of Minnesota, Minneapolis, MN 55455, USA
    Child Dev 75:497-504. 2004
    b>Tympanic membrane (TM) temperature asymmetry has been proposed as a phenotypic marker of vulnerability to negative emotionality in children...
  44. ncbi Biomechanics of the tympanic membrane
    G Volandri
    Department of Mechanical, Nuclear and Production Engineering, University of Pisa, Largo Lucio Lazzarino, 1 56126 Pisa, Italy
    J Biomech 44:1219-36. 2011
    The tympanic membrane is a key component of the human auditory apparatus which is a complex biomechanical system, devoted to sound reception and perception...
  45. ncbi Increased attentiveness is associated with hemispheric asymmetry measured with lateral tympanic membrane temperature in humans and dogs
    William S Helton
    Department of Psychology, University of Canterbury, Christchurch, New Zealand
    Exp Brain Res 219:321-6. 2012
    ..There was no discernable relationship between hyperactivity and lateralized T(Ty). Differences in T(Ty) may be an useful tool for investigating species comparisons of cerebral lateralization...
  46. ncbi Tympanic membrane temperature, exposure to emotional stimuli and the sustained attention to response task
    William S Helton
    Michigan Technological University, Houghton, MI, USA
    J Clin Exp Neuropsychol 31:611-6. 2009
    In this study lateral differences in tympanic membrane temperature (TMT) were explored as an index of cerebral lateralization...
  47. ncbi Sustained attention to local and global target features is different: performance and tympanic membrane temperature
    William S Helton
    Department of Cognitive and Learning Sciences, Michigan Technological University, Houghton, MI 49931, USA
    Brain Cogn 71:9-13. 2009
    ..b>Tympanic membrane temperature (TMT) was utilized in this study as an index of cerebral activation...
  48. ncbi The effect of investigator gender on lateral tympanic membrane temperature
    William S Helton
    Department of Psychology, University of Canterbury, Christchurch, New Zealand
    Laterality 16:156-63. 2011
    The measurement of tympanic membrane temperature (TMT) using hand-held infrared devices is common in both clinical and experimental research. However, the role that measurement context has on TMT has been overlooked...
  49. ncbi Mechanical properties of human tympanic membrane in the quasi-static regime from in situ point indentation measurements
    Jef Aernouts
    Laboratory of Biomedical Physics, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Hear Res 290:45-54. 2012
    The tympanic membrane is a key component of the human auditory apparatus. Good estimates of tympanic membrane mechanical properties are important to obtain realistic models of middle ear mechanics...
  50. ncbi Tympanic membrane regeneration using a water-soluble chitosan patch
    Jang Ho Kim
    Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul, Republic of Korea
    Tissue Eng Part A 16:225-32. 2010
    Chronic otitis media or tympanic membrane (TM) perforation is one of the most common otologic diseases. Surgical tympanoplasty remains the best treatment option despite the fact that paper patches are frequently used...
  51. ncbi Collagen type distribution in the healthy human tympanic membrane
    Johan Knutsson
    Center for Hearing and Communication Research, Karolinska Institute, Stockholm, Sweden
    Otol Neurotol 30:1225-9. 2009
    A weakening of the collagen fibers of the lamina propria of the tympanic membrane is a prerequisite for the formation of a retraction pocket. The various collagen types differ in tensile strength...
  52. ncbi Fresh tympanic membrane perforations heal without significant loss of strength
    Anisur Rahman
    Center for Hearing and Communication Research and Department of Otorhinolaryngology, Karolinska University Hospital and Institute, Stockholm, Sweden
    Otol Neurotol 26:1100-6. 2005
    The mechanical and structural properties of the tympanic membrane change after a perforation has healed.
  53. ncbi Structural and functional properties of the healed tympanic membrane: a long-term follow-up after laser myringotomy
    Anisur Rahman
    Center for Hearing and Communication Research and Department of Otorhinolaryngology, Karolinska University Hospital and Institute, Stockholm, Sweden
    Otol Neurotol 28:685-91. 2007
    ..The short-term healing scar that forms after experimental laser myringotomy will revert to a normal lamina propria in the long run. The mechanical stiffness will stay normal...
  54. ncbi The relationship between lateral differences in tympanic membrane temperature and behavioral impulsivity
    William S Helton
    Department of Psychology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Brain Cogn 74:75-8. 2010
    In this study lateral differences in tympanic membrane temperature (T(Ty)) were explored as a correlate of either impulsive or cautious responding in Go-No-Go tasks...
  55. ncbi Tympanosclerosis: long-term hearing results after ossicular reconstruction
    Karen Borne Teufert
    House Ear Institute and University of Southern California, School of Medicine, Los Angeles 90057, USA
    Otolaryngol Head Neck Surg 126:264-72. 2002
    ..The study goal was to analyze long-term hearing results and factors likely to affect outcome after ossicular reconstruction in patients with tympanosclerosis, particularly tympanosclerotic stapes fixation...
  56. pmc The use of infrared ear thermometers in pediatric and family practice offices
    B G Silverman
    Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U S Food and Drug Administration, Rockville, MD 20850, USA
    Public Health Rep 113:268-72. 1998
    ..To describe the use of infrared (IR) ear thermometers in pediatric and family practice offices...
  57. ncbi Effects of posture and age on tympanic membrane displacement measurements
    A J Phillips
    MRC Institute of Hearing Research, Royal South Hants Hospital, Southampton
    Br J Audiol 23:279-84. 1989
    ..sitting upright and then at 63 degrees to the vertical, using a technique which measures displacement of the tympanic membrane in response to acoustic stimulation of the stapedial reflex...
  58. ncbi A comparison of different methods of temperature measurements in sick newborns
    Sinan Uslu
    Department of Pediatrics, Division of Neonatology, Sisli Etfal Children Hospital, Istanbul, Turkey
    J Trop Pediatr 57:418-23. 2011
    ..2°C) between both mean AGMT&DAT and AGMT&ITT measurements. Our study suggests that tympanic thermometer measurement could be used as an acceptable and practical method for sick newborn in neonatal units...
  59. ncbi Sensitivity of functional tympanic membrane thermometry (fTMT) as an index of hemispheric activation in cognition
    Nicolas Cherbuin
    School of Psychology, Building 39, Australian National University, Canberr, Australia
    Laterality 12:239-61. 2007
    ..The present study was conducted to determine whether infrared functional tympanic membrane thermometry (fTMT) is a measure of lateralised activation sensitive enough to be used in typical cognitive ..
  60. pmc Finite element modeling of sound transmission with perforations of tympanic membrane
    Rong Z Gan
    School of Aerospace and Mechanical Engineering, University of Oklahoma, Norman, Oklahoma 73019, USA
    J Acoust Soc Am 126:243-53. 2009
    ..In this paper, the FE model was used to predict the effect of tympanic membrane (TM) perforations on sound transmission through the middle ear...
  61. ncbi Accuracy and feasibility of daily infrared tympanic membrane temperature measurements in the identification of fever in children
    Birgit K van Staaij
    Julius Center for Health Sciences and Primary Care, University Medical Center stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Int J Pediatr Otorhinolaryngol 67:1091-7. 2003
    ..The infrared tympanic membrane thermometer (ITT) seems ideal for measuring central body temperature...
  62. ncbi Vibration characteristics and function of atelectatic segments in the tympanic membrane in fresh human cadaveric temporal bones
    D P Morris
    The Ear and Auditory Research Laboratory EAR Lab, Dalhousie University, Halifax, Nova Scotia, Canada
    Clin Otolaryngol Allied Sci 29:133-7. 2004
    ..They may be associated with a mild conductive hearing loss and often coexist with other tympanic membrane and middle ear abnormalities...
  63. ncbi Prognosis and outcome of the tympanic membrane flap at traumatic tympanic membrane perforation edge
    Zheng Cai Lou
    Department of Otorhinolaryngology, Yiwu Central Hospital, Zhejiang, China
    ORL J Otorhinolaryngol Relat Spec 73:212-8. 2011
    This study aimed to retrospectively evaluate the prognosis and outcome of tympanic membrane perforations with a particular focus on the fate of the perforation edge flaps...
  64. ncbi Eustachian tube function in adults with intact tympanic membrane
    Renata Rumy Makibara
    Federal University of Sao Paulo UNIFESP, Brazil
    Braz J Otorhinolaryngol 76:340-6. 2010
    ..The Eustachian tube has the function of equilibrating the environmental pressure with inner pressure, protecting the middle ear from abrupt pressure changes...
  65. ncbi Functional effects of repeated pressure loads upon the tympanic membrane: mechanical stiffness measurements after simulated habitual sniffing
    Magnus von Unge
    Department of ENT, Karolinska Hospital and Institute, Stockholm, Sweden
    Eur Arch Otorhinolaryngol 266:1219-24. 2009
    In experimental studies it was found that otitis media causes stiffness loss in the tympanic membrane, possible precursors to retraction pockets and cholesteatoma...
  66. ncbi Immunohistochemical study of cell proliferation using BrdU labelling on tympanic membrane, external auditory canal and induced cholesteatoma in Mongolian gerbils
    K Park
    Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea
    Acta Otolaryngol 119:874-9. 1999
    ..known whether keratin accumulation can increase the proliferative activity of the keratinizing epithelium in tympanic membrane and meatal skin...
  67. ncbi Cognition is cool: Can hemispheric activation be assessed by tympanic membrane thermometry?
    Nicolas Cherbuin
    Australian National University, School of Psychology, Building 39, Canberra, ACT 0200, Australia
    Brain Cogn 54:228-31. 2004
    ..This study investigated whether tympanic membrane thermometry could be used as a broad measure of hemispheric activation...
  68. ncbi Tympanic membrane abnormalities and hearing levels at the ages of 5 and 6 years in relation to persistent otitis media and tympanostomy tube insertion in the first 3 years of life: a prospective study incorporating a randomized clinical trial
    Lindsay C Johnston
    Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Pediatrics 114:e58-67. 2004
    ..Our objective in the present study was to examine the prevalence of various tympanic membrane (TM) abnormalities in otherwise healthy children at the age of 5 years and hearing levels at the age of 6 ..
  69. pmc Tympanic membrane boundary deformations derived from static displacements observed with computerized tomography in human and gerbil
    Stefan L R Gea
    Biomedical Physics, University of Antwerp, Groenenborgerlaan 171, 2020, Antwerp, Belgium
    J Assoc Res Otolaryngol 11:1-17. 2010
    ..We have, therefore, studied the deformation of the tympanic membrane (TM) at its boundaries using X-ray microscopic computed tomography in human and gerbil while static pressure ..
  70. pmc The use of infrared thermometry for the detection of fever
    Alastair D Hay
    Division of Primary Health Care, University of Bristol
    Br J Gen Pract 54:448-50. 2004
    ..Infrared thermometry is too insensitive to be used as a screening test for fever, but when fever is already suspected, for example by touch, it may be useful as a 'rule in' test...
  71. pmc Lateralized changes in tympanic membrane temperature in relation to different cognitive tasks in chimpanzees (Pan troglodytes)
    W D Hopkins
    Division of Psychobiology, Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia 30322, USA
    Behav Neurosci 112:83-8. 1998
    Lateralized changes in tympanic membrane (TM) temperature were assessed in chimpanzees. Subjects were engaged in 1 of 3 different cognitive tasks, including matching-to-sample, visual-spatial discrimination, and a motor task...
  72. ncbi Virtual biopsy of rat tympanic membrane using higher harmonic generation microscopy
    Wen Jeng Lee
    National Taiwan University, Department of Electrical Engineering, Taipei, Taiwan
    J Biomed Opt 15:046012. 2010
    ..back-propagating multiple optical harmonics, combining second and third harmonics, is applied in unfixed rat tympanic membrane. We show that third harmonic generation can provide morphologic information on the epithelial layers of rat ..
  73. ncbi Cholesterol granuloma in the tympanic membrane
    Shin Ichi Haginomori
    Department of Otolaryngology and Division of Surgical Pathology, Central Clinical Pathology, Osaka Medical College, Takatsuki, Japan
    Otol Neurotol 27:1201-2. 2006
  74. ncbi The tympanic membrane: a biochemical updating of structural components
    D Broekaert
    Laboratory of Physiological Chemistry, University of Ghent, Belgium
    Acta Otorhinolaryngol Belg 49:127-37. 1995
    A cross-section of the tympanic membrane is discussed at the molecular level. Actually, the tympanic membrane can be described as a continuation of a vast number of structural proteins and molecular interactions...
  75. pmc Human beta-defensin-1 mRNA is transcribed in tympanic membrane and adjacent auditory canal epithelium
    R Bøe
    Departments of Experimental Pathology, University of Tromso, Tromso, Norway
    Infect Immun 67:4843-6. 1999
    ..By reverse transcriptase PCR we demonstrate HBD-1 mRNA in the pars tensa and pars flaccida of the tympanic membrane and in the meatal skin...
  76. ncbi Oesophageal, rectal, axillary, tympanic and pulmonary artery temperatures during cardiac surgery
    J Robinson
    Department of Pediatrics, University of Alberta, Edmonton, Canada
    Can J Anaesth 45:317-23. 1998
    ..Measurement of this gradient was done in patients undergoing rapid changes in body temperature to establish the best site to measure temperature and to compare two brands of commercial tympanic thermometers...
  77. ncbi The overlooked importance of tympanic membrane bulging
    Hunter Hoover
    Pediatrics 115:513; author reply 513-4. 2005
  78. ncbi Sweet's syndrome affecting the external auditory canal and tympanic membrane
    Walid R Saliba
    Department of Medicine C, Ha Emeq Medical Center, Faculty of Medicine, Afula, Israel
    J Laryngol Otol 118:48-9. 2004
    ..Identical lesions developed also in the external auditory canal and the tympanic membrane of the affected ear...
  79. ncbi Calcium deposition and expression of bone modelling markers in the tympanic membrane following acute otitis media
    Giedre Raustyte
    Department of Ear, Nose and Throat Diseases, Kaunas University of Medicine, Lithuania
    Int J Pediatr Otorhinolaryngol 70:529-39. 2006
    ..process and the sclerotic plaques of the drum mimics features of bone tissue, this study explores tympanic membrane calcium deposition in association with the expression of three bone modelling markers: osteopontin (OPN), ..
  80. ncbi Vibrometric studies of the middle ear of the bullfrog Rana catesbeiana I. The extrastapes
    Matthew J Mason
    Department of Physiological Science, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095, USA
    J Exp Biol 205:3153-65. 2002
    ..The ratio of tympanic membrane to footplate vibration velocity is significantly greater in male frogs than in female frogs...
  81. ncbi Tympanic membrane metalloproteinase inflammatory response
    Jason G Wilmoth
    Department of Otolaryngology, University of Florida, Gainesville, FL 32610 0264, USA
    Otolaryngol Head Neck Surg 129:647-54. 2003
    ....
  82. ncbi Cholesterol granuloma
    Arun K Gadre
    Department of Otolaryngology, University of Texas Health Science Center at Houston, USA
    Ear Nose Throat J 84:264. 2005
  83. ncbi Comparison of the mechanical performance of ossiculoplasty using a prosthetic malleus-to-stapes head with a tympanic membrane-to-stapes head assembly in a human cadaveric middle ear model
    Manohar Bance
    The Ear and Auditory Research Laboratory, Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Otol Neurotol 25:903-9. 2004
    ..result in better transmission of vibrations from the eardrum to the stapes footplate than reconstruction with a tympanic membrane assembly to the stapes head. Both types of reconstruction will be affected by tension of the prosthesis.
  84. ncbi The effects of hyaluronic acid, epidermal growth factor, and mitomycin in an experimental model of acute traumatic tympanic membrane perforation
    Enis Alpin Guneri
    Department of Otolaryngology, Dokuz Eylul University Medical School, Izmir, Turkey
    Otol Neurotol 24:371-6. 2003
    The goal of this study was to evaluate the effects of hyaluronic acid, epidermal growth factor, and mitomycin C on the healing of acute experimental traumatic perforations of the tympanic membrane.
  85. ncbi Structure and function of the tympanic membrane: a review
    D J Lim
    Laboratory of Cellular Biology, National Institute on Deafness and Other Communication Disorders (NIDCD, National Institutes of Health (NIH, Rockville, MD 20850, USA
    Acta Otorhinolaryngol Belg 49:101-15. 1995
    ..in the last three decades of research on morphological, cell biological, and immunobiological aspects of the tympanic membrane of laboratory animals and humans are reviewed...
  86. ncbi Otoacoustic emissions at compensated middle ear pressure in children
    J R Hof
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Maastricht, The Netherlands
    Int J Audiol 44:317-20. 2005
    ..These results show that measuring OAEs at compensated middle ear pressure enhances the amplitude of TEOAEs, and thus improves the detectability...
  87. ncbi Anterior atticoantrostomy for cholesteatoma surgery
    Yavuz Uyar
    Department of Otolaryngology, Meram Faculty of Medicine, Selcuk University, Konya, Turkey
    Ann Otol Rhinol Laryngol 115:150-5. 2006
    ..We aimed to investigate the long-term results of anterior atticoantrostomy in adult patients with cholesteatoma...
  88. ncbi Does passive smoking affect the outcome of grommet insertion in children?
    C V Praveen
    Department of ENT, Princess Royal University Hospital, Kent, UK
    J Laryngol Otol 119:448-54. 2005
    ..infection rate, attic retraction, post-extrusion myringosclerosis and permanent perforations of tympanic membrane were more common in children exposed to passive smoking...
  89. ncbi Subannular ventilation tubes: retrospective study
    Jean François Cloutier
    Otolaryngology Program, University of Montreal, Montreal, QC
    J Otolaryngol 34:312-6. 2005
    To evaluate the efficiency of a subannular tube insertion technique in a group of pediatric patients with adhesive otitis or severe atelectasis of the tympanic membrane.
  90. ncbi Outcome of myringotomy with ventilation tube for otitis media with effusion in Thai children: Ramathibodi experiences
    Kunchitthape Tanpowpong
    Department of Otolaryngology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Rd, Ratchathevi, Bangkok 10400, Thailand
    J Med Assoc Thai 90:1866-71. 2007
    ..Study the otologic and audiologic outcome when using a ventilation tube (VT) for the treatment of otitis media with effusion (OME) in Thai children...
  91. ncbi The use of tympanometry and pneumatic otoscopy for predicting middle ear disease
    Paula K Harris
    Midwest Ear, Nose and Throat Clinic, Herrin, IL, USA
    Am J Audiol 14:3-13. 2005
    ..The goal of this study was to evaluate the effectiveness of otoscopy and multifrequency tympanometry (MFT) for diagnosis of otitis media in children...
  92. ncbi Cross-linked hydrogels for middle ear packing
    Albert H Park
    Division of Otolaryngology Head and Neck Surgery, University of Utah, School of Medicine, Salt Lake City, Utah 84132, USA
    Otol Neurotol 27:1170-5. 2006
    ..To develop an ideal supportive packing material for ossiculoplasty, tympanoplasty, or other otologic procedures...
  93. ncbi Natural course of tympanic membrane pathology related to otitis media and ventilation tubes between ages 8 and 18 years
    B A De Beer
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Otol Neurotol 26:1016-21. 2005
    To present the course of tympanic membrane pathology in childhood and young adulthood after otitis media (OM) in early life.
  94. ncbi Fistula of the cochlear labyrinth in noncholesteatomatous chronic otitis media
    Luca O Redaelli de Zinis
    Department of Otolaryngology, Head and Neck Surgery, University of Brescia, Brescia, Italy
    Otol Neurotol 26:830-3. 2005
    ..To discuss the clinical aspects and management of promontory fistula of the cochlear labyrinth...
  95. ncbi Evidence-based review of aetiopathogenic theories of congenital and acquired cholesteatoma
    R Persaud
    Department of Otolaryngology, Northwick Park Hospital, Harrow, UK
    J Laryngol Otol 121:1013-9. 2007
    ..Congenital cholesteatoma develops behind a normal, intact tympanic membrane, whilst acquired cholesteatoma is associated with a defect in the tympanic membrane...
  96. ncbi Fully implantable hearing aids in patients with congenital auricular atresia
    Ralf Siegert
    Prosper Hospital, Academic Teaching Hospital of Ruhr University Bochum, Recklinghausen, Germany
    Laryngoscope 117:336-40. 2007
    ..and modified by us into a three-step procedure with in vivo prefabrication of the external ear canal and the tympanic membrane. Although the results improved after inauguration of our modifications, there still remains an air-bone gap ..
  97. ncbi [Recommendations for treatment of retraction pockets]
    Andreas Neumann
    Laryngorhinootologie 86:92-4. 2007
  98. ncbi The middle ear of cleft palate patients in their early teens: a literature study and preliminary file study
    K Timmermans
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Belgium
    B-ENT 2:95-101. 2006
    ....
  99. ncbi Wheel-shaped cartilage-perichondrium composite graft for the prevention of retraction pocket development
    Seung Ho Shin
    Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea
    Acta Otolaryngol 127:25-8. 2007
    ..The wheel-shaped cartilage-perichondrium composite graft (Wheel CPCG) can be considered a good material for a drum graft, and it is easy to insert a ventilation tube, in case of initial drum retraction...
  100. ncbi [Results of treatment with tympanostomy tubes in children with otitis media with effusion]
    Beata Zielnik-Jurkiewicz
    Oddział Otolaryngologiczny, Szpital Dzieciecy SZPZOZ im prof J Bogdanowicza w Warszawie
    Otolaryngol Pol 60:181-5. 2006
    ..However some pathological changes of the tympanic membrane and middle ear few years after treatment are observed...
  101. ncbi Correlations between rapid maxillary expansion (RME) and the auditory apparatus
    Andrea Villano
    Department of Orthodontics, University of Pisa, Italy
    Angle Orthod 76:752-8. 2006
    ..To evaluate the effects of rapid maxillary expansion (RME) on conductive hearing loss and maxillary constriction...

Research Grants62

  1. Ultrasound Characterization of Otitis Media
    Arne Voie; Fiscal Year: 2004
    ..which can be inserted into the external ear canal and deliver a low-intensity burst of ultrasound to the tympanic membrane and the middle ear space...
  2. Human middle-ear imaging, physiology, and biomechanics
    CHARLES RICHARD STEELE; Fiscal Year: 2013
    ..will be used to understand how to improve high-frequency outcomes of middle-ear surgical treatments, such as tympanic membrane repair (myringoplasty) and ossicle replacement with a prosthesis (tympanoplasty)...
  3. Middle-ear Mechanics in Normal and Pathological Ears
    John J Rosowski; Fiscal Year: 2013
    ..methods and use new tools such as external-ear acoustic reflectance and laser holography of motion of the tympanic membrane in order to: a) investigate correlations between ear canal reflectance and umbo velocity in normal and ..
  4. Avian Middle Ear Development
    SUSAN CAROLINE CHAPMAN; Fiscal Year: 2012
    ..include, microtia, atresia, cholesteatoma, exostoses, otoschlerosis, glomus tumor, myringosclerosis of the tympanic membrane, otitis media and trauma...
  5. Ossicle vibration measurements in conductive hearing loss
    Steven L Jacques; Fiscal Year: 2013
    ..The proposal develops a hand-held otoscope that uses optical coherence tomography (OCT) to image the tympanic membrane and ossicles behind an intact tympanic membrane...
  6. Biomechanical Measurement and Modeling of Normal and Diseased Middle Ears
    Rong Z Gan; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The middle ear, composed of ossicles and soft tissues including the tympanic membrane, ligaments, and joints plays a vital role in the transmission of sound and the sense of hearing...
  7. Molded Hydrogel Tympanic Membrane Repair Constructs
    WILSON CANNOY PRITCHARD; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): Tympanic membrane perforations are commonly seen in otology practices and about 150,000 repair surgeries are performed each year in the United States...
  8. Dx Ear: An automated tool for diagnosis of otitis media
    JELENA KOVACEVIC; Fiscal Year: 2010
    ..into one of three stringent clinical diagnostic categories (AOM/OME/NOE), and validate the algorithm on tympanic membrane (TM) images...
  9. Computer-based holography and middle-ear function
    John J Rosowski; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The tympanic membrane (TM) (or eardrum) is the initial structure in the middle-ear's acoustic-mechanical transformation of environmental sounds to sound within the inner ear...
  10. Backward and Forward Driven Eardrum Motions
    Jeffrey Tao Cheng; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Sound-induced displacement of the Tympanic Membrane (TM) is the first stage in the forward transformation of environmental sound to sound within the cochlea, while displacement of the TM induced by ..
  11. Wide-bandwidth open canal hearing aid for better multitalker speech understanding
    Sunil Puria; Fiscal Year: 2009
    ..the current acoustic transducer with a non-acoustic mechanical output transducer that directly actuates the tympanic membrane. This transducer, called the EarLens, floats on the tympanic membrane in a manner similar to the way a ..
  12. Innovative therapy for diseases of the middle ear
    Allen F Ryan; Fiscal Year: 2013
    ..tympanostomy tubes which provide aeration and allow the penetration of topical medications through the tympanic membrane. Such local drug treatment has been found to be highly effective...
  13. OTITIS MEDIA RESEARCH CENTER
    Charles Bluestone; Fiscal Year: 1990
    ..for chronic OME indicate that M&T does provide children with less morbidity, but perforation of the tympanic membrane is a complication; final two years treatment/observation needed...
  14. Effects of aging on evoked otoacoustic emissions in the common marmoset
    Rama Ratnam; Fiscal Year: 2010
    ..e. emissions that are elicited in response to acoustic stimulation of the tympanic membrane)...
  15. Function of the human tympanic membrane
    JEFFREY CHENG; Fiscal Year: 2009
    Forty years ago, it was clearly demonstrated that the sound-induced motions of the surface of the tympanic membrane (the TM or eardrum) are complicated in both their spatial response and frequency dependence...
  16. ULTRASONIC MEASURMENT OF MIDDLE EAR FLUID VISCOSITY
    STEVEN AFRICK; Fiscal Year: 2000
    ..All acoustic excitation and measurements will be made through the tympanic membrane to minimize the invasiveness of the procedure making it suitable for a number of clinical settings...
  17. Wide-bandwidth open canal hearing aid for better multitalker speech understanding
    Sunil Puria; Fiscal Year: 2006
    ..the current acoustic transducer with a non-acoustic mechanical output transducer that directly actuates the tympanic membrane. This transducer, called the EarLens, floats on the tympanic membrane in a manner similar to the way a ..
  18. AGE EFFECTS IN MIDDLE EAR REFLECTANCE MEASUREMENT
    M Feeney; Fiscal Year: 2001
    Anatomical studies have shown that the ossicular joints and tympanic membrane stiffen with age...
  19. Crosslinkable Hydrogels for Tympanic Membrane Repair
    Glenn Prestwich; Fiscal Year: 2004
    b>Tympanic membrane perforation (TMP, or "ruptured eardrum") is a common occurrence caused by trauma, ear infections, or pressure equalization tube insertion...
  20. ULTRASONIC DETECTION OF MIDDLE EAR EFFUSION
    Jan Lewandowski; Fiscal Year: 2004
    ..noninvasive detection of middle ear effusion based on the analysis of ultrasonic echoes reflected from the tympanic membrane and the middle ear cavity. We achieved a statistically significant (P = 0...
  21. POSTNATAL AUDITORY FUNCTION DEVELOPMENT
    GEORGE STRAIN; Fiscal Year: 1991
    ..Auditory stimuli will be introduced through stimulus delivery tubing implanted on the tympanic membrane to bypass the sealed ear canal...
  22. MECHANISMS OF TISSUE DESTRUCTION IN CHOLESTEATOMA
    BRIAN FADDIS; Fiscal Year: 2007
    Cholesteatomas are epithelial tumor-like growths that arise from the tympanic membrane, typically as a sequela of chronic otitis media...
  23. COMPACT, FIBER OPTIC HOLOGRAHIC PROBE FOR OTOLARYNGOLOGY
    James Castracane; Fiscal Year: 1991
    ..a pressurizer tube, a clear channel for acoustic stimulation and lenses to focus the light reflected from the tympanic membrane upon the semi-transparent screen, creating the interference image in conjunction with the reference beam.
  24. EVALUATION OF A NON-INVASIVE GLUCOSE MONITOR
    JANUSZ BUCHERT; Fiscal Year: 2004
    ..The method and instrument are based on the discovery that natural mid-infrared emissions, from the tympanic membrane, consist of spectral information of blood analytes...
  25. CORE TEMPERATURE MEASUREMENT IN HYPOTHERMIA
    ROBERT TUCKETT; Fiscal Year: 1990
    ..In contrast, tympanic membrane temperatures have been reported to accurately reflect core temperatures in steady state conditions and to ..
  26. Ear Biomechanics for Restoration of Hearing
    RONG GAN; Fiscal Year: 2009
    ..to measure mechanical properties or viscoelasticity of middle ear tissues such as the ligaments and tympanic membrane;(3) to develop multi-field (i.e...
  27. Development of a laser holography otoscope for diagnosis in the clinic
    John J Rosowski; Fiscal Year: 2010
    ..are relatively easily diagnosed on otologic examination, the cause of conductive loss with an intact tympanic membrane (TM) and dry middle ear is not easily determined...
  28. Middle-ear assessment via reflectance measurements
    Susan Voss; Fiscal Year: 2005
    ..This work will both strengthen the research environment at Smith College and provide substantial research experiences for undergraduate students. ..
  29. Vestibular Recovery after Intratympanic Gentamicin
    John Carey; Fiscal Year: 2004
    ..Furthermore, the mechanisms of vestibular recovery may help us understand the potential for the inner ear to recover from a variety of injuries. ..
  30. Evalution of Vestibular Function in Meniere's Disease
    John Carey; Fiscal Year: 2009
    ..Comparisons of angular and translational VOR deficits after intratympanic gentamicin should demonstrate whether or not the utricle is less susceptible than the semicircular canals to intratympanic gentamicin. ..
  31. VESTIBULAR EFFECTS OF INTRATYMPANIC GENTAMICIN
    John Carey; Fiscal Year: 2005
    ..Johns Hopkins is uniquely suited to this training because it has a core group devoted to vestibular research, and the mentor's laboratory has successfully used all of the techniques required. ..
  32. Exploring otoacoustic emissions with intracochlear pressure measurements
    Wei Dong; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  33. The Effects of Resveratrol on Presbyacusis
    Michael Seidman; Fiscal Year: 2004
    ..Furthermore, these data will provide novel strategies to impart greater wellness in the elderly population and perhaps have a positive effect on health care expenses. ..
  34. Function of Vestibular-Nerve Afferent Types
    Timothy Hullar; Fiscal Year: 2008
    ..Findings from this study will allow better understanding of pathologies of the peripheral vestibular system. ..
  35. Development of Improved Earphone for Hearing Testing
    Robert Margolis; Fiscal Year: 2008
    ..In this project an earphone is being developed that can be used in both automated and manual testing and will significantly increase the efficiency, accuracy, and accessibility. [unreadable] [unreadable] [unreadable]..
  36. MEASUREMENT OF VESTIBULAR FUNCTION IN MENIERE'S DISEASE
    Steven Rauch; Fiscal Year: 2002
    ....
  37. From infra- to ultrasound: Diversity in acoustic processing by the vertebrate ear
    Peter M Narins; Fiscal Year: 2010
    ..Ultimately, our research may lead to new therapeutic approaches to treatment of hyperacusis and noise-induced tinnitus, two known syndromes in which efferent system malfunction has been implicated. ..
  38. Biomechanical Evaluation of Eustachian Tube Dysfunction
    Samir N Ghadiali; Fiscal Year: 2010
    ..This information is vital to the development of novel treatment therapies that seek to restore normal ET function in patients with OM. ..
  39. TROPHIC MANIPULATIONS OF THE OCULOMOTOR SYSTEM
    Christopher S von Bartheld; Fiscal Year: 2010
    ....
  40. Sudden Hearing Loss Multicenter Treatment Trial
    Steven Rauch; Fiscal Year: 2008
    ..Thus the results of this study will have significant impact on evidence-based clinical practice guidelines for management of SSNHL. This application is for the collaborating Clinical Coordinating Center (CCC). ..
  41. Differential Gene Expression in the Cochlear Nucleus
    David Friedland; Fiscal Year: 2008
    ..These data will also provide a powerful template upon which to test and design novel treatments for improving hearing, discrimination and tinnitus in a significant portion of the population. ..
  42. 5th Intn'l.Symp.:Meniere's Disease/Inner Ear Homeostasis
    David Lim; Fiscal Year: 2005
    ..abstract_text> ..
  43. CLINICAL MEASURES OF AUDITORY LINEAR/NONLINEAR PROCESSES
    MARK CHERTOFF; Fiscal Year: 2004
    ..abstract_text> ..
  44. OAE Group Delay Measurements Using Tone-Burst Stimuli
    ROBERT WITHNELL; Fiscal Year: 2004
    ....
  45. Recent Advancees in Otitis Media: Research Conference
    David Lim; Fiscal Year: 2003
    ..Additionally, we plan to post the panel reports on HEI's otitis media web page (with permission from the publisher). ..
  46. Aged Middle Ear
    MICHAELANNE GRATTON; Fiscal Year: 2002
    ..The comparison begins with i careful morphological assessment of the tympanic membrane using light and transmission electron microscopy in these two age groups...
  47. ADJUSTMENT OF INTERNATIONALLY ADOPTED CHILDREN
    Megan Gunnar; Fiscal Year: 2002
    ..This work will add significantly to our understanding of the health and behavioral sequelae of early adversity and th potential impact of early adversity on stress-sensitive limbic-hypothalamic processes. ..
  48. GENETICS OF A NEW MOUSE MODEL FOR DEAFNESS
    Qing Zheng; Fiscal Year: 2002
    ..Aim 2. Construct a physical contig of YACS and BACS clones across the minimal genetic region. Aim 3. Fully characterize the development and pathology of inner ears from hml/hml mice compared with hml/+ and +/+ controls. ..
  49. Non-Surgical Device for Treatment of Middle Ear Effusion
    Shlomo Silman; Fiscal Year: 2002
    ..Although the custom-made device costs $325 including product liability, when commercially produced, it will cost about $5.00. ..
  50. Psychobiological studies of stress in young children
    Megan Gunnar; Fiscal Year: 2005
    ..We argue that normative developmental research complements and provides basic data necessary for research and theory on developmental psychopathology. ..
  51. Early Experience, Stress Neurobiology & Prevention Sci
    Megan Gunnar; Fiscal Year: 2005
    ....
  52. Ninth Research Conference on Recent Advances in Otitis Media
    David Lim; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  53. Transcriptome and Proteome Analysis of Mouse Inner Ears
    Qing Zheng; Fiscal Year: 2007
    ..Genes, proteins and their molecular pathways identified in this proposed research are potential targets of drug therapies for hearing loss that affects more than 28 million Americans. ..
  54. Galvanic Effects on the Human Vestibuloocular Reflex
    Americo Migliaccio; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  55. Physiological Studies of Age-Related Hearing Loss
    RICHARD SCHMIEDT; Fiscal Year: 2007
    ..Taken together, the three aims explore the major causes and effects of metabolic presbyacusis and have direct application to future interventions to help restore age-related hearing loss. [unreadable] [unreadable]..
  56. Molecular biology of deafness in the Meniere's Model
    CLIFF MEGERIAN; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  57. COCHLEAR MECHANICS
    WILLIAM RHODE; Fiscal Year: 2007
    ..Mechanical measurements will be compared I to auditory nerve responses in the same species and using the same signals. ..
  58. Vestibular Pathology in Meniere's Disease
    Akira Ishiyama; Fiscal Year: 2007
    ..or with alterations in neuronal number or size? 6) What are the morphometric correlates to abnormalities on traditional vestibular testing: caloric paresis, and decreased gain and time constant on step rotational testing? ..
  59. Developmental Psychobiology of Stress in Children
    Megan Gunnar; Fiscal Year: 2006
    ..abstract_text> ..
  60. Automated Test of Word Recognition - Phase II
    Robert Margolis; Fiscal Year: 2006
    ..A pilot study will test the method on a Spanish-language speech-recognition test. [unreadable] [unreadable]..
  61. H. INFLUENZAE HMW ADHESION PROTEINS IN HOST IMMUNITY
    Stephen Barenkamp; Fiscal Year: 2002
    ..abstract_text> ..